EP0166325A3 - Process and device for the selective separation of pathological and/or toxic species from blood or plasma with the use of filter candles - Google Patents

Process and device for the selective separation of pathological and/or toxic species from blood or plasma with the use of filter candles Download PDF

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Publication number
EP0166325A3
EP0166325A3 EP85107364A EP85107364A EP0166325A3 EP 0166325 A3 EP0166325 A3 EP 0166325A3 EP 85107364 A EP85107364 A EP 85107364A EP 85107364 A EP85107364 A EP 85107364A EP 0166325 A3 EP0166325 A3 EP 0166325A3
Authority
EP
European Patent Office
Prior art keywords
plasma
pathological
blood
filter candles
toxic species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP85107364A
Other versions
EP0166325A2 (en
EP0166325B1 (en
Inventor
Gerhard Dr. Rosskopf
Dietrich Dr. Seidel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B Braun Surgical AG
Original Assignee
Intermedicat GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermedicat GmbH filed Critical Intermedicat GmbH
Priority to AT85107364T priority Critical patent/ATE48087T1/en
Publication of EP0166325A2 publication Critical patent/EP0166325A2/en
Publication of EP0166325A3 publication Critical patent/EP0166325A3/en
Application granted granted Critical
Publication of EP0166325B1 publication Critical patent/EP0166325B1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3482—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B01D61/146—Ultrafiltration comprising multiple ultrafiltration steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/06—Tubular membrane modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption

Abstract

A process and device for the selective separation of pathological and/or toxic species from blood, plasma or serum wherein a plasma or serum fraction is passed through a container containing one or more filter candles of decreasing mean pore diameter and which may contain a sterilizable spacing disc between the filter candles. In accordance with the invention, macromolecular phatological and/or toxic species with molecular weight exclusion limits between about 20,000 and 3,000,000 D may be selectively separated from a fraction of plasma or serum.
EP85107364A 1984-06-16 1985-06-14 Process and device for the selective separation of pathological and/or toxic species from blood or plasma with the use of filter candles Expired EP0166325B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT85107364T ATE48087T1 (en) 1984-06-16 1985-06-14 METHOD AND DEVICE FOR THE SELECTIVE SEPARATION OF PATHOLOGICAL AND/OR TOXIC PARTS FROM BLOOD OR PLASMA USING FILTER CARTRIDGES.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843422435 DE3422435A1 (en) 1984-06-16 1984-06-16 METHOD AND DEVICE FOR SELECTIVELY SEPARATING PATHOLOGICAL AND / OR TOXIC SPECIES FROM BLOOD OR BLOOD PLASMA USING FILTER CANDLES
DE3422435 1984-06-16

Publications (3)

Publication Number Publication Date
EP0166325A2 EP0166325A2 (en) 1986-01-02
EP0166325A3 true EP0166325A3 (en) 1987-04-08
EP0166325B1 EP0166325B1 (en) 1989-11-23

Family

ID=6238537

Family Applications (1)

Application Number Title Priority Date Filing Date
EP85107364A Expired EP0166325B1 (en) 1984-06-16 1985-06-14 Process and device for the selective separation of pathological and/or toxic species from blood or plasma with the use of filter candles

Country Status (7)

Country Link
US (1) US4816162A (en)
EP (1) EP0166325B1 (en)
JP (1) JPS6171063A (en)
AT (1) ATE48087T1 (en)
DE (2) DE3422435A1 (en)
ES (2) ES8608877A1 (en)
ZA (1) ZA854507B (en)

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DE4004794A1 (en) * 1990-02-16 1991-08-22 Bayer Ag Cartridge filter for high viscosity materials - which has replaceable sleeve
GB9218239D0 (en) * 1992-08-27 1992-10-14 Pall Corp Processing of protein-containing body fluids
GB9302043D0 (en) * 1993-02-03 1993-03-24 Optokem Instr Ltd Size exclusion chromatography
US5424265A (en) * 1993-06-15 1995-06-13 Safetec Of America Capsule for absorbing liquid waste in a suction canister
US6322697B1 (en) 1999-07-19 2001-11-27 Donaldson Company, Inc. Oil filter assembly
WO2002065125A1 (en) * 2001-02-13 2002-08-22 Invitrogen Corporation Methods and compositions for isolation of biological macromolecules
US6706008B2 (en) 2001-03-06 2004-03-16 Baxter International Inc. Automated system and method for withdrawing compounds from blood
US6582386B2 (en) 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
US6884228B2 (en) 2001-03-06 2005-04-26 Baxter International Inc. Automated system adaptable for use with different fluid circuits
DE10118446A1 (en) * 2001-04-12 2002-10-17 Thomas Hartung Test for microbiological toxins, e.g. for testing gases, comprises using a flow vessel with a separator, to incubate separated toxins similar to whole blood incubation, for study on a mediator
WO2005012487A2 (en) * 2003-08-01 2005-02-10 Invitrogen Corporation Compositions and methods for preparing short rna molecules and other nucleic acids
EP1611907A1 (en) * 2004-06-29 2006-01-04 Herbener, Heinz-Gerd Blood processing apparatus
US7481910B2 (en) * 2004-06-30 2009-01-27 Taiwan Semiconductor Manufacturing Co., Ltd. Method and apparatus for stabilizing plating film impurities
WO2006017284A2 (en) * 2004-07-12 2006-02-16 Schroeder Industries, Llc Replaceable filter element with integral annular trap
WO2013103906A1 (en) * 2012-01-04 2013-07-11 Medtronic, Inc. Multi-staged filtration system for blood fluid removal
US10850016B2 (en) 2013-02-01 2020-12-01 Medtronic, Inc. Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection
US9623164B2 (en) 2013-02-01 2017-04-18 Medtronic, Inc. Systems and methods for multifunctional volumetric fluid control
US10010663B2 (en) 2013-02-01 2018-07-03 Medtronic, Inc. Fluid circuit for delivery of renal replacement therapies
US9827361B2 (en) 2013-02-02 2017-11-28 Medtronic, Inc. pH buffer measurement system for hemodialysis systems
US9144640B2 (en) 2013-02-02 2015-09-29 Medtronic, Inc. Sorbent cartridge configurations for improved dialysate regeneration
CN103251994B (en) * 2013-04-02 2016-03-30 周春华 A kind of for the blood kettle device under swing vibration condition
US9713665B2 (en) 2014-12-10 2017-07-25 Medtronic, Inc. Degassing system for dialysis
US10874787B2 (en) 2014-12-10 2020-12-29 Medtronic, Inc. Degassing system for dialysis
US10098993B2 (en) 2014-12-10 2018-10-16 Medtronic, Inc. Sensing and storage system for fluid balance
DE102015216241A1 (en) * 2015-08-25 2017-03-02 Bbi-Biotech Gmbh Container and method for filtering a suspension
DE102016107024A1 (en) * 2016-04-15 2017-10-19 B. Braun Avitum Ag Method and device for extracorporeal blood treatment
DE102017116923A1 (en) * 2017-07-26 2019-01-31 Sartorius Stedim Biotech Gmbh Disposable filter capsules for a filtration device
US11278654B2 (en) 2017-12-07 2022-03-22 Medtronic, Inc. Pneumatic manifold for a dialysis system
US11033667B2 (en) 2018-02-02 2021-06-15 Medtronic, Inc. Sorbent manifold for a dialysis system
US11110215B2 (en) 2018-02-23 2021-09-07 Medtronic, Inc. Degasser and vent manifolds for dialysis
US20210308604A1 (en) * 2020-04-01 2021-10-07 Stonehouse Innovations, LLC Fluid treatment system having concentric chambers

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US4209392A (en) * 1978-05-15 1980-06-24 Wallace Richard A Portable hepatic-assist method and apparatus for same
DE8030211U1 (en) * 1980-11-12 1981-03-19 F.A.S. Fabrik automatischer Schaltapparate Hans Jörgensen GmbH & Co, 2000 Hamburg REPLACEMENT INSERTS FOR FILTER AND CLEANING DEVICES
EP0041350A2 (en) * 1980-05-29 1981-12-09 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
EP0079221A2 (en) * 1981-11-06 1983-05-18 Baylor College of Medicine Immune complex removal and tumor specific antibody generation by immobilized protein a perfusion and postperfusion drug infusion
DE3310727A1 (en) * 1983-03-24 1984-10-04 B. Braun Melsungen Ag, 3508 Melsungen METHOD AND DEVICE FOR SELECTIVE, EXTRACORPORAL SEPARATION OF PATHOLOGICAL AND / OR TOXIC BLOOD COMPONENTS

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EP0041350A2 (en) * 1980-05-29 1981-12-09 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
DE8030211U1 (en) * 1980-11-12 1981-03-19 F.A.S. Fabrik automatischer Schaltapparate Hans Jörgensen GmbH & Co, 2000 Hamburg REPLACEMENT INSERTS FOR FILTER AND CLEANING DEVICES
EP0079221A2 (en) * 1981-11-06 1983-05-18 Baylor College of Medicine Immune complex removal and tumor specific antibody generation by immobilized protein a perfusion and postperfusion drug infusion
DE3310727A1 (en) * 1983-03-24 1984-10-04 B. Braun Melsungen Ag, 3508 Melsungen METHOD AND DEVICE FOR SELECTIVE, EXTRACORPORAL SEPARATION OF PATHOLOGICAL AND / OR TOXIC BLOOD COMPONENTS

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MEDIZINAL-MARKT/ACTA MEDICOTECHNICA, vol. 24, no. 1, 1976, pages 3-7, Munich; H. PERL et al.: "Membranen für biochemische Methoden" *

Also Published As

Publication number Publication date
ES544161A0 (en) 1986-08-01
DE3574342D1 (en) 1989-12-28
ZA854507B (en) 1986-02-26
JPS6171063A (en) 1986-04-11
ES8608877A1 (en) 1986-08-01
DE3422435A1 (en) 1986-01-16
ATE48087T1 (en) 1989-12-15
EP0166325A2 (en) 1986-01-02
US4816162A (en) 1989-03-28
ES8704083A1 (en) 1987-03-16
EP0166325B1 (en) 1989-11-23
ES553015A0 (en) 1987-03-16

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