EP0302228A3 - Probe for measuring the activity of ions and use thereof - Google Patents

Probe for measuring the activity of ions and use thereof Download PDF

Info

Publication number
EP0302228A3
EP0302228A3 EP19880110465 EP88110465A EP0302228A3 EP 0302228 A3 EP0302228 A3 EP 0302228A3 EP 19880110465 EP19880110465 EP 19880110465 EP 88110465 A EP88110465 A EP 88110465A EP 0302228 A3 EP0302228 A3 EP 0302228A3
Authority
EP
European Patent Office
Prior art keywords
probe
activity
measuring
ions
membranes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19880110465
Other languages
German (de)
French (fr)
Other versions
EP0302228B1 (en
EP0302228A2 (en
Inventor
Werner Pfab
Michael Bergmann
Paul-Gerhard Fenzlein
Wolfgang Anderer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIEGERT ELECTRONIC GMBH
Original Assignee
SIEGERT electronic GmbH
Siegert GmbH Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873725597 external-priority patent/DE3725597A1/en
Application filed by SIEGERT electronic GmbH, Siegert GmbH Co filed Critical SIEGERT electronic GmbH
Publication of EP0302228A2 publication Critical patent/EP0302228A2/en
Publication of EP0302228A3 publication Critical patent/EP0302228A3/en
Application granted granted Critical
Publication of EP0302228B1 publication Critical patent/EP0302228B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495Calibrating or testing of in-vivo probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/333Ion-selective electrodes or membranes
    • G01N27/3335Ion-selective electrodes or membranes the membrane containing at least one organic component

Abstract

A probe for measuring the activity of ions employs ion-selective membranes (4). To improve the measurement possibilities and reduce the size of such a probe, a plurality of such membranes (4) are held in a common carrier (3) and insulated both electrically and against the ingress of moisture. Take-off terminals (2) are furthermore provided in a probe body (1), carrier (3) and probe body (1) being interconnected. A process is also provided for producing such a probe, and the invention also includes probes and associated apparatus for haemodialysis. <IMAGE>
EP88110465A 1987-08-01 1988-06-30 Probe for measuring the activity of ions and use thereof Expired - Lifetime EP0302228B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3725597 1987-08-01
DE19873725597 DE3725597A1 (en) 1987-08-01 1987-08-01 Ionometric sensor
DE3810186 1988-03-25
DE3810186A DE3810186A1 (en) 1987-08-01 1988-03-25 SENSOR FOR MEASURING THE ACTIVITY OF IONS AND METHOD FOR THE PRODUCTION THEREOF

Publications (3)

Publication Number Publication Date
EP0302228A2 EP0302228A2 (en) 1989-02-08
EP0302228A3 true EP0302228A3 (en) 1990-09-05
EP0302228B1 EP0302228B1 (en) 1997-03-12

Family

ID=25858205

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88110465A Expired - Lifetime EP0302228B1 (en) 1987-08-01 1988-06-30 Probe for measuring the activity of ions and use thereof

Country Status (6)

Country Link
US (1) US5018527A (en)
EP (1) EP0302228B1 (en)
JP (1) JPS6450948A (en)
CN (1) CN1031280A (en)
AT (1) ATE150174T1 (en)
DE (2) DE3810186A1 (en)

Families Citing this family (23)

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US6246894B1 (en) * 1993-02-01 2001-06-12 In-Line Diagnostics Corporation System and method for measuring blood urea nitrogen, blood osmolarity, plasma free hemoglobin and tissue water content
US5284568A (en) * 1992-07-17 1994-02-08 E. I. Du Pont De Nemours And Company Disposable cartridge for ion selective electrode sensors
US6241947B1 (en) * 1998-01-27 2001-06-05 Fuji Photo Film Co., Ltd. Chemical analysis system and blood filtering unit
US5992211A (en) * 1998-04-23 1999-11-30 Medtronic, Inc. Calibrated medical sensing catheter system
US6767440B1 (en) * 2001-04-24 2004-07-27 Roche Diagnostics Corporation Biosensor
JP2001178817A (en) 1999-12-24 2001-07-03 Terumo Corp Device for artificial kidney, quality evaluating device using the same and fluid circuit
US6849168B2 (en) * 2000-11-13 2005-02-01 Kval, Inc. Electrochemical microsensor package
US6780307B2 (en) * 2001-10-12 2004-08-24 The United States Of America As Represented By The Secretary Of The Navy Ion selective electrodes for direct organic drug analysis in saliva, sweat, and surface wipes
DE10229210A1 (en) * 2002-06-28 2004-01-29 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Device for the detection of an analyte
US20050059105A1 (en) * 2003-07-25 2005-03-17 Board Of Trustees Of Michigan State University Impedimetric biosensor and its use for rapid detection of bacterial pathogens in solution
CN1614404A (en) * 2003-11-07 2005-05-11 华广生技股份有限公司 Electrochemcial sensor
DE10353938A1 (en) * 2003-11-18 2005-06-23 Fresenius Medical Care Deutschland Gmbh Sensor card for the determination of analytes in liquid or gas samples and method for producing such a sensor card
GB2441784A (en) * 2006-09-13 2008-03-19 Rtc North Ltd Device for obtaining and analysing a biological fluid
EP1936365B1 (en) * 2006-12-22 2014-03-05 Metroglas AG Method of determining a reference electrode on an ion-selective electrode having a solid contact
WO2011034168A1 (en) * 2009-09-18 2011-03-24 日立化成工業株式会社 Ion selective electrode cartridge
JP2011112405A (en) * 2009-11-24 2011-06-09 Toshiba Corp Electronic device
DE102010015551A1 (en) * 2010-04-13 2011-10-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Ion-sensitive sensor element
CN102455310B (en) * 2010-10-14 2013-10-16 中国科学院过程工程研究所 Device for measuring surface resistance of ion exchange membrane through AC (alternating current) method
CN102590312B (en) * 2012-02-08 2014-09-10 张关池 Method for preparing ion selective film electrode by solid melting method
FI20126315L (en) 2012-12-14 2014-06-15 Bo Akademi Reference electrode and arrangement for electrochemical measurement
ES2571755B1 (en) 2014-11-26 2017-03-10 Universitat Autònoma De Barcelona Continuous and real-time monitoring probe of chemical parameters of interest directly on land and system for continuous and real-time monitoring of said chemical parameters of interest
US11519788B2 (en) * 2017-03-06 2022-12-06 President And Fellows Of Harvard College Elastomeric temperature sensor
US11175544B2 (en) 2017-03-07 2021-11-16 President And Fellows Of Harvard College Stretchable electrooptical and mechanooptical devices comprising a liquid crystal cell disposed between first and second ionic conducting gel layers

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1560716A (en) * 1967-03-09 1969-03-21
FR2428839A1 (en) * 1978-06-16 1980-01-11 Sclavo Inst Sieroterapeut ELECTRODES SYSTEM HAVING A REFERENCE ELECTRODE WITHOUT LIQUID JUNCTION FOR VOLTAMETRIC MEASUREMENTS
FR2445525A1 (en) * 1978-12-27 1980-07-25 Orion Research ELECTROCHEMICAL ELECTRODE SENSITIVE TO THE PRESENCE OF AN X- HALIDE ION IN SOLUTION, AND ITS MANUFACTURING METHOD
EP0021626A1 (en) * 1979-06-27 1981-01-07 Beckman Instruments, Inc. Salts of phosphoric acid diesters, their preparation and use in membranes, the membranes and their use in calcium ion determination, and the electrodes containing them
EP0061810A2 (en) * 1981-03-31 1982-10-06 Philippe Bogard Measuring apparatus comprising an electrode with a solid-state sensitive element, and method of manufacturing
US4370983A (en) * 1971-01-20 1983-02-01 Lichtenstein Eric Stefan Computer-control medical care system
EP0102042A2 (en) * 1982-08-28 1984-03-07 Kabushiki Kaisha Toshiba Ion selective electrode device and ion analyzing apparatus
EP0115346A1 (en) * 1983-01-28 1984-08-08 Hitachi, Ltd. Liquid film type, anion-selective electrode
DD221368A1 (en) * 1983-12-22 1985-04-24 Messgeraetewerk Zwonitz Veb K APPARATUS FOR AUTOMATIC EFFECTIVITY DETERMINATION IN HAEMODIALYSIS
EP0155068A1 (en) * 1984-01-19 1985-09-18 Integrated Ionics, Inc. Ambient sensing devices
EP0186286A1 (en) * 1984-10-31 1986-07-02 Unilever N.V. Apparatus for use in electrical, e.g. electrochemical, measurement procedures, and its production and use and composite assemblies incorporating the apparatus
EP0193676A1 (en) * 1985-02-07 1986-09-10 Spectramed, Inc. Solid state electrode
EP0204260A2 (en) * 1985-06-04 1986-12-10 Gambro AB A monitor for the control and/or checking of two or more functions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2726450C3 (en) * 1977-06-11 1982-01-14 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg Catheter measuring arrangement for electrochemical analysis
US4340457A (en) * 1980-01-28 1982-07-20 Kater John A R Ion selective electrodes
CA1183461A (en) * 1981-05-01 1985-03-05 Russell L. Jeffery Dialysate preparation apparatus
DE3216791A1 (en) * 1981-05-15 1982-12-02 Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt Method and system for measuring ion concentrations
DE3223051C2 (en) * 1982-06-21 1984-09-13 Fresenius AG, 6380 Bad Homburg Dialysis device with regulated dialysis solution
US4600495A (en) * 1983-08-03 1986-07-15 Medtronic, Inc. Flow through ion selective electrode

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1560716A (en) * 1967-03-09 1969-03-21
US4370983A (en) * 1971-01-20 1983-02-01 Lichtenstein Eric Stefan Computer-control medical care system
FR2428839A1 (en) * 1978-06-16 1980-01-11 Sclavo Inst Sieroterapeut ELECTRODES SYSTEM HAVING A REFERENCE ELECTRODE WITHOUT LIQUID JUNCTION FOR VOLTAMETRIC MEASUREMENTS
FR2445525A1 (en) * 1978-12-27 1980-07-25 Orion Research ELECTROCHEMICAL ELECTRODE SENSITIVE TO THE PRESENCE OF AN X- HALIDE ION IN SOLUTION, AND ITS MANUFACTURING METHOD
EP0021626A1 (en) * 1979-06-27 1981-01-07 Beckman Instruments, Inc. Salts of phosphoric acid diesters, their preparation and use in membranes, the membranes and their use in calcium ion determination, and the electrodes containing them
EP0061810A2 (en) * 1981-03-31 1982-10-06 Philippe Bogard Measuring apparatus comprising an electrode with a solid-state sensitive element, and method of manufacturing
EP0102042A2 (en) * 1982-08-28 1984-03-07 Kabushiki Kaisha Toshiba Ion selective electrode device and ion analyzing apparatus
EP0115346A1 (en) * 1983-01-28 1984-08-08 Hitachi, Ltd. Liquid film type, anion-selective electrode
DD221368A1 (en) * 1983-12-22 1985-04-24 Messgeraetewerk Zwonitz Veb K APPARATUS FOR AUTOMATIC EFFECTIVITY DETERMINATION IN HAEMODIALYSIS
EP0155068A1 (en) * 1984-01-19 1985-09-18 Integrated Ionics, Inc. Ambient sensing devices
EP0186286A1 (en) * 1984-10-31 1986-07-02 Unilever N.V. Apparatus for use in electrical, e.g. electrochemical, measurement procedures, and its production and use and composite assemblies incorporating the apparatus
EP0193676A1 (en) * 1985-02-07 1986-09-10 Spectramed, Inc. Solid state electrode
EP0204260A2 (en) * 1985-06-04 1986-12-10 Gambro AB A monitor for the control and/or checking of two or more functions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biomedizinische Technik, Band 22, Nr. 9, Seiten 209-211, 1977; J.G. SCHINDLER et al.: "Ionselektive Multi-Disk-Elektrode" *

Also Published As

Publication number Publication date
JPS6450948A (en) 1989-02-27
US5018527A (en) 1991-05-28
DE3810186A1 (en) 1989-10-05
EP0302228B1 (en) 1997-03-12
ATE150174T1 (en) 1997-03-15
CN1031280A (en) 1989-02-22
DE3855817D1 (en) 1997-04-17
EP0302228A2 (en) 1989-02-08

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