EP0690727A4 - Hexadentate ligands useful in radiographic imaging agents - Google Patents

Hexadentate ligands useful in radiographic imaging agents

Info

Publication number
EP0690727A4
EP0690727A4 EP94907172A EP94907172A EP0690727A4 EP 0690727 A4 EP0690727 A4 EP 0690727A4 EP 94907172 A EP94907172 A EP 94907172A EP 94907172 A EP94907172 A EP 94907172A EP 0690727 A4 EP0690727 A4 EP 0690727A4
Authority
EP
European Patent Office
Prior art keywords
radiographic imaging
imaging agents
ligands useful
hexadentate ligands
hexadentate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94907172A
Other languages
German (de)
French (fr)
Other versions
EP0690727A1 (en
Inventor
William L Neumann
Raghavan Rajagopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of EP0690727A1 publication Critical patent/EP0690727A1/en
Publication of EP0690727A4 publication Critical patent/EP0690727A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5027—Polyphosphines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
EP94907172A 1993-01-06 1994-01-04 Hexadentate ligands useful in radiographic imaging agents Withdrawn EP0690727A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1132 1987-01-05
US113293A 1993-01-06 1993-01-06
PCT/US1994/000281 WO1994015647A1 (en) 1993-01-06 1994-01-04 Hexadentate ligands useful in radiographic imaging agents

Publications (2)

Publication Number Publication Date
EP0690727A1 EP0690727A1 (en) 1996-01-10
EP0690727A4 true EP0690727A4 (en) 1996-03-06

Family

ID=21694536

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94907172A Withdrawn EP0690727A4 (en) 1993-01-06 1994-01-04 Hexadentate ligands useful in radiographic imaging agents

Country Status (4)

Country Link
EP (1) EP0690727A4 (en)
JP (1) JPH08505398A (en)
AU (1) AU6085294A (en)
WO (1) WO1994015647A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338864A (en) * 1992-07-06 1994-08-16 Mallinckrodt Medical, Inc. Hexadentate ligands useful in radiographic imaging agents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010466A1 (en) * 1990-12-14 1992-06-25 Mallinckrodt Medical, Inc. Hexadentate ligands useful in radiographic imaging agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3048480A (en) * 1959-06-09 1962-08-07 Gulf Research Development Co Aviation turbine fuels
US4795626A (en) * 1985-05-10 1989-01-03 University Of Cincinnati 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
US4917879A (en) * 1989-05-19 1990-04-17 University Of Cincinnati 99MTC(III) myocardial imaging agents that are effective in humans
US5112594A (en) * 1991-04-04 1992-05-12 Mallinckrodt Medical, Inc. Kit for preparing a technetium-99m myocardial imaging agent
US5112595A (en) * 1990-12-21 1992-05-12 Mallinckrodt Medical, Inc. 99MTC(III) myocardial imaging agents and method of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992010466A1 (en) * 1990-12-14 1992-06-25 Mallinckrodt Medical, Inc. Hexadentate ligands useful in radiographic imaging agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9415647A1 *

Also Published As

Publication number Publication date
WO1994015647A1 (en) 1994-07-21
JPH08505398A (en) 1996-06-11
EP0690727A1 (en) 1996-01-10
AU6085294A (en) 1994-08-15

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950725

AK Designated contracting states

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Designated state(s): DE FR

RHK1 Main classification (correction)

Ipc: C07F 9/50

A4 Supplementary search report drawn up and despatched

Effective date: 19960118

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Withdrawal date: 19960724