EP0751752B1 - Aufweitbarer stent - Google Patents

Aufweitbarer stent Download PDF

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Publication number
EP0751752B1
EP0751752B1 EP95935320A EP95935320A EP0751752B1 EP 0751752 B1 EP0751752 B1 EP 0751752B1 EP 95935320 A EP95935320 A EP 95935320A EP 95935320 A EP95935320 A EP 95935320A EP 0751752 B1 EP0751752 B1 EP 0751752B1
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EP
European Patent Office
Prior art keywords
stent
shaped wall
repeating pattern
wall
longitudinal axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP95935320A
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English (en)
French (fr)
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EP0751752A1 (de
Inventor
Ian M. Penn
Donald R. Ricci
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Divysio Solutions ULC
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Divysio Solutions ULC
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Priority to EP98103164A priority Critical patent/EP0847734B1/de
Publication of EP0751752A1 publication Critical patent/EP0751752A1/de
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Publication of EP0751752B1 publication Critical patent/EP0751752B1/de
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/954—Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2002/065—Y-shaped blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/828—Means for connecting a plurality of stents allowing flexibility of the whole structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91525—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91575—Adjacent bands being connected to each other connected peak to trough

Definitions

  • the present invention relates to an expandable stent as specified in the preamble of Claim 1.
  • a stent is e.g. known from EP-A-0 566 807.
  • Stents are generally known. Indeed, the term “stent” has been used interchangeably with terms such as “intraluminal vascular graft” and “expansible prosthesis”. As used throughout this specification the term “stent” is intended to have a broad meaning and encompasses any expandable prosthetic device for implantation in a body passageway (e.g. a lumen or artery).
  • a body passageway e.g. a lumen or artery
  • body passageway is intended to have a broad meaning and encompasses any duct (e.g. natural or iatrogenic) within the human body and can include a member selected from the group comprising: blood vessels, respiratory ducts, gastrointestinal ducts and the like.
  • a stent in association with a balloon, is delivered to the target area of the body passageway by a catheter system.
  • the target area of the body passageway can be filled with a contrast medium to facilitate visualization during fluoroscopy
  • the balloon is expanded thereby expanding the stent so that the latter is urged in place against the body passageway.
  • the amount of force applied is at least that necessary to maintain the patency of the body passageway.
  • the balloon is deflated and withdrawn within the catheter, and subsequently removed.
  • the stent will remain in place and maintain the target area of the body passageway substantially free of blockage (or narrowing).
  • Palmaz-SchatzTM Balloon Expandable Stent hereinafter referred to as "the Palmaz-Schatz stent"
  • Palmaz-Schatz stent This stent is discussed in a number of patents including United States patents 4,733,665, 4,739,762, 5,102,417 and 5,316,023.
  • Gianturco-Roubin Flex-StentTM Another stent which has gained some notoriety in the art is known as Gianturco-Roubin Flex-StentTM (hereinafter referred to as “the Gianturco-Roubin stent”). This stent is discussed in a number of patents including United States patents 4,800,882, 4,907,336 and 5,041,126.
  • a stent having a porous surface including a repeating pattern made of up a polygon having three parallel side walls (and parallel to the longitudinal axis of the stent) connected by a concave-shaped wall and a convex-shaped wall.
  • Each of the concave-shaped wall and the convex-shaped wall of the polygon in the subject stent are characterised by a pointed apex.
  • a stent having the provision of such a repeating pattern is fraught with the following deficiencies: the stent will not open properly upon application of an expansive force; upon expansion, the stent is susceptible to improper lifting at the intersection point (i.e., in a two-dimensional representation of the stent design, such lifting would be in a third dimension); the stent is relatively inflexible; the stent will not expand in a symmetrical fashion; and the stent can not be opened to a consistent degree using a consistent pressure.
  • stents described in the above-identified patents share the common design of being mono-tubular and thus, are best suited to be delivered and implanted in-line in the body passageway.
  • stents are inappropriate for use in a bifurcated body passageway (e.g. a body passageway comprising a parent passageway that splits into a pair of passageways).
  • stents are inappropriate for use in a body passageway having side branches since: (i) accurate placement of the stent substantially increases the risk to the patient, (ii) the risk of passageway closure in the side branches is increased, and (iii) the side branches will be substantially inaccessible.
  • bifurcation lesions within the coronary circulation.
  • these legions may be classified as follows: Type Characteristic A Prebranch stenosis not involving the ostium of the side branch; B Postbranch stenosis of the parent vessel not involving the origin of the side branch; C Stenosis encompassing the side branch but not involving the ostium; D Stenosis involving the parent vessel and ostium of the side branch; E Stenosis involving the ostium of the side branch only; and F Stenosis discretely involving the parent vessel and ostium of the side branch.
  • Atlas of Interventional Cardiology (Popma et al.), 1994, pages 77-79.
  • the presence of bifurcation lesions is predictive of increased procedural complications including acute vessel closure.
  • the present invention provides an expandable stent comprising a proximal end and a distal end in communication with one another, a tubular wall disposed between the proximal end and the distal end, the tubular wall having a longitudinal axis and a porous surface defined by a plurality of intersecting members integrally connected to one another at their points of intersection, the plurality of intersecting members defining a first repeating pattern which, in two dimensions and the unexpanded state of the stent, is a polygon having a pair of side walls substantially parallel to the longitudinal axis, a first concave-shaped wall and a second convex-shaped wall connecting the side walls, the stent comprising at least two circumferentially disposed rings of first repeating pattern, the stent being expandable from a first, contracted position in which the tubular wall is not folded along the longitudinal axis to a second, expanded position upon the application of a radially outward force on the stent, characterised in that both of the
  • the repeating pattern is a polygon having a pair of side walls substantially parallel to the longitudinal axis of the stent passageway in question, a first concave-shaped wall and a second convex-shaped wall connecting the side walls, the first wall and the second wall being equidistant along an axis which is parallel to the longitudinal axis of the stent passageway in question.
  • the terms "concave-shaped” and “convex-shaped” are intended to have a broad meaning and a shape having apex. The important point is that the apex of the concave-shaped wall is directed into the polygon whereas the apex of the convex-shaped wall is directed away from the polygon.
  • a preferred aspect of the present invention relates to the provision of an expandable bifurcated stent comprising the specific repeating pattern.
  • an expandable bifurcated stent comprising the specific repeating pattern.
  • the term "biffurcated stent” is intended to have a broad meaning and encompasses any stent having a primary passageway to which is connected at least two secondary passageways.
  • trifurcated stents are encompassed herein.
  • one of the secondary passageways can he a continuation of the primary passageway with the result that the other secondary passageway is essentially a side branch to the primary passageway.
  • this repeating pattern is useful in both the novel bifurcated stent described herein and conventional mono-tubular stents.
  • the advantages associated with the use of such a repeating pattern include the following:
  • the stent of the present invention can further comprise coating material therein.
  • the coating material can be one or more of a biologically inert material (i.e. to reduce the thrombogenicity of the stent), a medicinal composition which leaches in the wall of the body passageway after implantation (e.g. to provide anticoagulant action and the like).
  • Stent 10 comprises a proximal end 15 and a distal end 20.
  • Proximal end 15 comprises a primary passageway 25.
  • Distal end 20 comprises a pair of secondary passageways 30,35 .
  • Secondary passageways 30,35 are connected to primary passageway 25 at an intersection point 40.
  • the length of primary passageway 25 and secondary passageways 30,35 is particularly restricted and is select to optimize both deliverability of the stent (shorten) and vessel coverage (lengthen).
  • FIG 2 there is illustrated an enlarged perspective view of the bifurcated stent illustrated in Figure 1 in a second, expanded position.
  • secondary passageways 30,35 are split apart more than they are when the bifurcated stent is in the first, contracted position ( Figure 1).
  • primary passageway 25 and secondary passageways 30,35 are porous.
  • the porosity of these passageways is defined by a plurality of intersecting members 45.
  • Intersecting members 45 define a first repeating pattern designated A and a second repeating pattern designated B in Figure 2. The nature of first repeating pattern A and second repeating pattern B will be discussed in more detail hereinbelow with reference to Figure 4.
  • Stent 100 comprises a proximal end 105 and a distal end 110. Disposed between proximal end 105 and distal end 110 is a tubular wall 115. Tubular wall 115 is porous. The porosity of tubular wall 115 is defined by a plurality of intersecting members 120 which define a first repeating pattern A and second repeating pattern B.
  • first repeating pattern A and second repeating pattern B are illustrated with respect to a longitudinal axis 50 which is representative of the longitudinal axis which would be present in each of primary passageway 25, secondary passageways 30,35 and tubular wall 115 discussed above with reference to Figures 1, 2 and 3.
  • repeating pattern A is a polygon comprising a pair of side walls 55,60. Side walls 55,60 are substantially parallel to longitudinal axis 50. Side walls 55,60 are connected by a concave-shaped wall 65 and a convex-shaped wall 70.
  • concave-shaped wall 65 is made up of a trio of segments 66,67,68.
  • segment 67 is the apex of concave-shaped wall 65.
  • Convex-shaped wall 70 is made up of a trio of segments 71,72,73.
  • segment 72 is the apex of convex-shaped wall 70.
  • first repeating pattern A necessarily defines and provides for second repeating pattern B.
  • second repeating pattern B is a mirror image of first repeating pattern A taken along an axis (not shown) substantially normal to longitude general axis 50.
  • concave-shaped wall 65 and/or convex-shaped wall 70 can be modified without departing from the scope of the appended claims For example, more than three segments can be used to define concave-shaped wall 65 and/or convex-shaped wall 70.
  • intersection point 40 is an annular arrangement of second repeating pattern B which has been modified. Specifically, the modification is in two areas. First, a reinforcing bar 75 has been disposed between side walls 55,60 to connect segments 67 and 72. Second, a reinforcing segment 80 is provided midway between and has a similar shape to concave-shaped wall 65 and convex-shaped wall 70. These two areas of modification serve to reinforce intersection point 40. This facilitates alleviation of stresses under which this area of stent 10 is placed when it is expanded. It will of course be appreciated by those of skill in the art that modifications can be made to the design of intersection point 40. For example, the flexibility of stent 10 at intersection point 40 can be modified by judicious addition or omission of further reinforcing bars 75 and/or reinforcing segments 80.
  • bifurcated body passageway 150 comprised of a proximal passageway 155 and a pair of distal passageways 160,165.
  • bifurcated body passageway 150 comprises a Type "D" Bifurcation lesion having characteristic blockages 170,175,180.
  • Stent 10 is delivered to bifurcated body passageway 150 in the following manner. Initially, a pair of guidewires 185,190 are inserted into proximal passageway 155 such that guidewire 185 enters distal passageway 160 and guidewire 190 enters distal passageway 165.
  • the manner by which the guidewires are inserted is conventional and within the purview of a person skilled in the art.
  • stent 10 is positioned in association with a pair of catheters 195,200 (for clarity, the interior of stent 10 is not shown).
  • Catheter 195 has associated with it a balloon 205.
  • Catheter 200 has associated with it a balloon 210.
  • Balloons 205,210 substantially fill primary passageway 25 of stent 10.
  • Balloon 205 substantially fills secondary passageway 30 of stent 10.
  • Balloon 210 substantially fills secondary passageway 35 of stent 10.
  • the stent/catheter/balloon combination is delivered through proximal passageway 155 with the aid of guidewires 185,190.
  • predisposition of guidewires 185,190 serves to separate secondary passageways 30,35 to be disposed in distal passageways 160,165, respectively.
  • stent 10 is positioned in place.
  • balloons 205,210 are expanded resulting in implantation of stent 10 in the corresponding interior surfaces of proximal passageway 155 and distal passageways 160,165.
  • balloons 205,210 are collapsed.
  • catheters 195,200 and guidewires 185,190 have been removed leaving the implanted stent 10 shown in Figure 7.
  • blockages 170,175,180 are bulged radially outwardly in combination with the appropriate portions of proximal passageway 155 and distal passageways 160,165 resulting in a reduction in the overall blockage in bifurcated body passage 150.
  • implantation of stent 10 can be accomplished by various other means.
  • the balloon and guidewire would be design to mimic the bifuracted design of the stent.
  • the stent can be made of a suitable material which will expand when bifurcated body passageway 150 is flushed with a liquid having an elevated temperature (e.g. 65,6°C-71,1°C (150°F-160°F)).
  • stent 10 can be designed to expand upon the application of mechanical forces other than those applied by a balloon/catheter. Still further, stent 10 can be designed self-expanding to be implanted as described above. In this embodiment, the radially outward force exerted on the stent would be generated within the stent itself.
  • mono-tubular stent 100 depicted in Figure 3 this stent can be implanted using a system similar to the one described above with reference to bifurcated stent 10 ( Figures 5-7).
  • a single guidewire, catheter and balloon can be used to position and expand the stent.
  • Implantation of mono-tubular stents such as stent 100 is conventional and within the purview of a person skilled in the art.
  • mono-tubular stent 100 can be modified to provided localized reinforcement at certain points by judicious use of bars and segments similar to reinforcing bar 75 and reinforcing segment 80, respectively, used to reinforce intersection point 40 of stent 10 ( Figure 2).
  • the stent depicted in Figures 1-3 can be modified to omit, on a selected basis, first repeating pattern A and/or second repeating B with a view to improve flexibility of the stent and to allow access to other structures (e.g. side branches/arteries) outside the bounds of the stent.
  • first repeating pattern A and/or second repeating B with a view to improve flexibility of the stent and to allow access to other structures (e.g. side branches/arteries) outside the bounds of the stent.

Claims (9)

  1. Aufweitbarer Stent (10, 100) mit einem proximalen Ende (15, 105) und einem distalen Ende (20, 110), die miteinander in Verbindung stehen, mit einer hülsenförmigen Wand, die zwischen dem proximalen und dem distalen Ende angeordnet ist und eine Längsachse (50) aufweist sowie eine poröse Fläche, gebildet aus einer Mehrzahl von sich schneidenden Elementen (45, 120), die an ihren Schnittstellen integral miteinander verbunden sind und die ein erstes, sich wiederholendes Muster (A) bilden, das in zwei Dimensionen und bei nicht expandiertem Zustand des Stent ein Polygon mit einem Paar Seitenwänden (55, 60) ist, die im wesentlichen parallel zur Längsachse verlaufen, mit einer ersten konkaven Wand (65) und einer zweiten konvexen Wand (70), die die Seitenwände miteinander verbinden, ferner mit wenigstens zwei in Umfangsrichtung angeordneten Ringen des ersten sich wiederholenden Musters (A), so daß der Stent expandierbar ist zwischen einer ersten, kontrahierten Position, in welcher die hülsenförmige Wand entlang der Längsachse nicht gefaltet ist, und einer zweiten, expandierten Position nach dem Aufbringen einer radial auswärtigen Kraft auf den Stent, dadurch gekennzeichnet, daß die erste konkave Wand (65) und die zweite konvexe Wand (70) einen flachen Scheitel in Gestalt eines Segmentes (67, 72) aufweisen, das zur Längsachse senkrecht verläuft.
  2. Stent nach Anspruch 1, dadurch gekennzeichnet, daß die sich schneidenden Elemente ein zweites, sich wiederholendes Muster (B) bilden.
  3. Stent nach Anspruch 2, dadurch gekennzeichnet, daß das zweite sich wiederholende Muster im wesentlichen ein Spiegelbild des ersten sich wiederholenden Musters entlang einer zur Längsachse im wesentlichen senkrechten Linie gesehen ist.
  4. Stent nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß die erste und die zweite Wand im wesentlichen bogenförmig sind.
  5. Stent nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß die erste konkave Wand drei Segmente umfaßt.
  6. Stent nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß die zweite konvexe Wand drei Segmente umfaßt.
  7. Stent nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß die erste konkave und die zweite konvexe Wand jeweils drei Segmente umfassen.
  8. Stent nach einem der Ansprüche 1 bis 7, weiterhin umfassend eine hierauf befindliche Beschichtung.
  9. Stent nach Anspruch 8, dadurch gekennzeichnet, daß das Beschichtungsmaterial ausgewählt ist aus der Gruppe, umfassend ein biologisch inertes Material, eine medizinische Verbindung sowie Gemische hiervon.
EP95935320A 1994-11-03 1995-11-03 Aufweitbarer stent Expired - Lifetime EP0751752B1 (de)

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CA002134997A CA2134997C (en) 1994-11-03 1994-11-03 Stent
CA2134997 1994-11-03
PCT/CA1995/000628 WO1996014028A1 (en) 1994-11-03 1995-11-03 Expandable bifurcated stent and method for delivery of same

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Also Published As

Publication number Publication date
RU2180198C2 (ru) 2002-03-10
KR970706766A (ko) 1997-12-01
DK0751752T3 (da) 1999-03-22
ATE166783T1 (de) 1998-06-15
US5755771A (en) 1998-05-26
DE69529480T2 (de) 2003-11-27
DE69529480D1 (de) 2003-02-27
AU3739795A (en) 1996-05-31
CA2134997A1 (en) 1996-05-04
AU3678599A (en) 1999-10-28
HK1009322A1 (en) 1999-05-28
CZ297296B6 (cs) 2006-11-15
MX9703222A (es) 1998-03-31
CZ132997A3 (en) 1997-12-17
DE69502817D1 (de) 1998-07-09
KR100386784B1 (ko) 2004-02-19
ES2119487T3 (es) 1998-10-01
EP0847734B1 (de) 2003-01-22
EP0751752A1 (de) 1997-01-08
EP0847734A3 (de) 1998-11-11
DE69502817T2 (de) 1999-02-25
JP3825044B2 (ja) 2006-09-20
US6099560A (en) 2000-08-08
ATE231366T1 (de) 2003-02-15
JPH10508234A (ja) 1998-08-18
WO1996014028A1 (en) 1996-05-17
GR3027774T3 (en) 1998-11-30
EP0847734A2 (de) 1998-06-17
CA2134997C (en) 2009-06-02

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