EP1919273A4 - Tissue-characterization probe with effective sensor-to-tissue contact - Google Patents

Tissue-characterization probe with effective sensor-to-tissue contact Download PDF

Info

Publication number
EP1919273A4
EP1919273A4 EP06766215.5A EP06766215A EP1919273A4 EP 1919273 A4 EP1919273 A4 EP 1919273A4 EP 06766215 A EP06766215 A EP 06766215A EP 1919273 A4 EP1919273 A4 EP 1919273A4
Authority
EP
European Patent Office
Prior art keywords
tissue
effective sensor
characterization probe
contact
tissue contact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06766215.5A
Other languages
German (de)
French (fr)
Other versions
EP1919273A2 (en
EP1919273B1 (en
Inventor
Dan Hashimshony
Gil Cohen
Iddo Geltner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dune Medical Devices Ltd
Original Assignee
Dune Medical Devices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/196,732 external-priority patent/US8721565B2/en
Application filed by Dune Medical Devices Ltd filed Critical Dune Medical Devices Ltd
Publication of EP1919273A2 publication Critical patent/EP1919273A2/en
Publication of EP1919273A4 publication Critical patent/EP1919273A4/en
Application granted granted Critical
Publication of EP1919273B1 publication Critical patent/EP1919273B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6834—Means for maintaining contact with the body using vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843—Monitoring or controlling sensor contact pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6844—Monitoring or controlling distance between sensor and tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6885—Monitoring or controlling sensor contact pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6886—Monitoring or controlling distance between sensor and tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4417—Constructional features of apparatus for radiation diagnosis related to combined acquisition of different diagnostic modalities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015—By temperature mapping of body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0536—Impedance imaging, e.g. by tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
    • A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
    • A61B6/5229—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image
    • A61B6/5247—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data combining image data of a patient, e.g. combining a functional image with an anatomical image combining images from an ionising-radiation diagnostic technique and a non-ionising radiation diagnostic technique, e.g. X-ray and ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/13—Tomography
EP06766215.5A 2005-08-04 2006-08-06 Tissue-characterization probe with effective sensor-to-tissue contact Not-in-force EP1919273B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/196,732 US8721565B2 (en) 2005-08-04 2005-08-04 Device for forming an effective sensor-to-tissue contact
US11/350,102 US8116845B2 (en) 2005-08-04 2006-02-09 Tissue-characterization probe with effective sensor-to-tissue contact
PCT/IL2006/000908 WO2007015255A2 (en) 2005-08-04 2006-08-06 Tissue-characterization probe with effective sensor-to-tissue contact

Publications (3)

Publication Number Publication Date
EP1919273A2 EP1919273A2 (en) 2008-05-14
EP1919273A4 true EP1919273A4 (en) 2017-09-06
EP1919273B1 EP1919273B1 (en) 2018-10-10

Family

ID=37709009

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06766215.5A Not-in-force EP1919273B1 (en) 2005-08-04 2006-08-06 Tissue-characterization probe with effective sensor-to-tissue contact

Country Status (7)

Country Link
US (2) US8116845B2 (en)
EP (1) EP1919273B1 (en)
JP (2) JP2009508539A (en)
CN (1) CN103271718B (en)
CA (1) CA2616962A1 (en)
ES (1) ES2704827T3 (en)
WO (1) WO2007015255A2 (en)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7505811B2 (en) 2001-11-19 2009-03-17 Dune Medical Devices Ltd. Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus
US20070255169A1 (en) * 2001-11-19 2007-11-01 Dune Medical Devices Ltd. Clean margin assessment tool
US20080154090A1 (en) * 2005-01-04 2008-06-26 Dune Medical Devices Ltd. Endoscopic System for In-Vivo Procedures
US8116845B2 (en) 2005-08-04 2012-02-14 Dune Medical Devices Ltd. Tissue-characterization probe with effective sensor-to-tissue contact
US7720532B2 (en) 2004-03-23 2010-05-18 Dune Medical Ltd. Clean margin assessment tool
US8032211B2 (en) * 2002-01-04 2011-10-04 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US8721565B2 (en) * 2005-08-04 2014-05-13 Dune Medical Devices Ltd. Device for forming an effective sensor-to-tissue contact
US8019411B2 (en) * 2002-01-04 2011-09-13 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US7809425B2 (en) * 2003-07-24 2010-10-05 Dune Medical Devices Ltd. Method and apparatus for examining a substance, particularly tissue, to characterize its type
US9750425B2 (en) 2004-03-23 2017-09-05 Dune Medical Devices Ltd. Graphical user interfaces (GUI), methods and apparatus for data presentation
WO2008072238A2 (en) 2006-12-12 2008-06-19 Dune Medical Devices Ltd. Graphical user interfaces (gui), methods and apparatus for data presentation
US7904145B2 (en) 2004-03-23 2011-03-08 Dune Medical Devices Ltd. Clean margin assessment tool
CN101991415B (en) * 2005-03-29 2013-04-10 沙丘医疗设备有限公司 Electromagnetic sensors for tissue characterization
US7511492B2 (en) * 2006-02-21 2009-03-31 Beth Israel Deaconess Medical Center, Inc. Magnetic resonance imaging and radio frequency impedance mapping methods and apparatus
CA2693315A1 (en) * 2006-07-27 2008-01-31 Tasc Ltd. High definition impedance imaging
US8147423B2 (en) 2007-03-01 2012-04-03 Dune Medical Devices, Ltd. Tissue-characterization system and method
JP4598791B2 (en) * 2007-03-13 2010-12-15 ゼネラル・エレクトリック・カンパニイ Breast immobilization device and breast imaging method
US9999353B2 (en) 2007-07-16 2018-06-19 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
US9757098B2 (en) 2007-07-16 2017-09-12 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
EP2178443B1 (en) 2007-07-16 2015-07-08 Dune Medical Devices Ltd. Medical device for use in tissue characterization and treatment
US9901362B2 (en) 2007-07-16 2018-02-27 Dune Medical Devices Ltd. Medical device and method for use in tissue characterization and treatment
US7685721B2 (en) * 2007-07-19 2010-03-30 Allergan, Inc. Breast implant selector systems
SE531527C2 (en) * 2007-10-01 2009-05-12 Bioresonator Ab Method and apparatus for unaffected material examination
DE102007057874A1 (en) * 2007-11-20 2009-05-28 Optris Gmbh Infrared camera has measuring head which is partially incorporated or contained in housing, where housing is provided with interface for connection with computer by cable
SE0801139L (en) * 2008-05-16 2009-11-17 Samba Sensors Ab Method and apparatus for examining physical quantity in a liquid or gas-filled element
ES2627041T3 (en) 2008-06-11 2017-07-26 Dune Medical Devices Ltd. Double registration
US20110105889A1 (en) * 2008-07-17 2011-05-05 Konica Minolta Medical & Graphic, Inc. Nanoparticle labeling and system using nanoparticle labeling
WO2010017192A1 (en) 2008-08-05 2010-02-11 Ph Diagnostics Inc. Apparatus, method and system for determining a physiological condition within a mammal
US8125331B2 (en) * 2008-08-27 2012-02-28 The Invention Science Fund I, Llc Health-related signaling via wearable items
US8130095B2 (en) * 2008-08-27 2012-03-06 The Invention Science Fund I, Llc Health-related signaling via wearable items
US8094009B2 (en) * 2008-08-27 2012-01-10 The Invention Science Fund I, Llc Health-related signaling via wearable items
US8284046B2 (en) 2008-08-27 2012-10-09 The Invention Science Fund I, Llc Health-related signaling via wearable items
US20100056873A1 (en) * 2008-08-27 2010-03-04 Allen Paul G Health-related signaling via wearable items
US20100081926A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081927A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081915A1 (en) * 2008-09-29 2010-04-01 Searete Llc, Alimited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
US20100081916A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware. Histological facilitation systems and methods
US20100081924A1 (en) * 2008-09-29 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Histological facilitation systems and methods
EP2348978B1 (en) * 2008-10-03 2017-12-06 HLZ Innovation, Llc Adjustable pneumatic supporting surface
US10820825B2 (en) * 2008-10-22 2020-11-03 Cornell University Method and device for evaluation of local tissue's biological or biomechanical character
JP5605783B2 (en) * 2009-06-10 2014-10-15 国立大学法人静岡大学 Diagnostic equipment
FR2951283B1 (en) * 2009-10-08 2013-02-15 Commissariat Energie Atomique METHOD AND DEVICE FOR DIFFUSED EXCITATION IN IMAGING
US8581584B2 (en) * 2010-05-26 2013-11-12 Florida State University Research Foundation Membrane proteins, mechanisms of action and uses thereof
US8686335B2 (en) 2011-12-31 2014-04-01 Seno Medical Instruments, Inc. System and method for adjusting the light output of an optoacoustic imaging system
US9289191B2 (en) 2011-10-12 2016-03-22 Seno Medical Instruments, Inc. System and method for acquiring optoacoustic data and producing parametric maps thereof
EP2745762A4 (en) * 2011-08-17 2015-01-21 Olympus Medical Systems Corp Optical measuring device and probe
US20130338475A1 (en) 2012-06-13 2013-12-19 Seno Medical Instruments, Inc. Optoacoustic imaging system with fiber optic cable
WO2013106385A2 (en) * 2012-01-09 2013-07-18 The Trustees Of Columbia University In The City Of New York System and methods for determining tissue elasticity
EP3586757A1 (en) * 2012-06-13 2020-01-01 Seno Medical Instruments, Inc. Optoacoustic imaging system with fiber optic cable
JP6470173B2 (en) 2012-07-12 2019-02-13 デューン メディカル デヴァイシズ リミテッドＤｕｎｅ Ｍｅｄｉｃａｌ Ｄｅｖｉｃｅｓ Ｌｔｄ． Medical device used for tissue characterization and treatment
KR20140133672A (en) * 2013-05-09 2014-11-20 삼성전자주식회사 Ultrasound Probe
US9186064B2 (en) * 2013-08-20 2015-11-17 The United States Of America As Represented By The Secretary Of The Army Internal optical spectroscope and method for real time in-situ diagnosis in living cells
PT3117777T (en) 2014-03-12 2020-06-17 Integral Geometry Science Inc Scattering tomography method and scattering tomography device
CZ306601B6 (en) * 2014-07-17 2017-03-22 Vysoká Škola Báňská-Technická Univerzita Ostrava A device for measuring and recording stiffness characteristics of tissues
KR102033759B1 (en) * 2014-09-23 2019-10-17 주식회사 한독칼로스메디칼 Catheter and manufacturing method thereof
US20180028100A1 (en) * 2015-02-11 2018-02-01 Siemens Aktiengesellschaft System and non-invasive method for examining at least parts of blood fractions, and use of the system
IL238034B (en) * 2015-03-30 2018-05-31 Shmri Haim Ltd System and hand-held probe for non-invasive real time analysis of body tissue
WO2017013512A1 (en) * 2015-07-17 2017-01-26 Koninklijke Philips N.V. Intravascular devices, systems, and methods with an adhesively attached shaping ribbon
EP3308695B1 (en) * 2016-10-11 2019-08-14 Nokia Technologies OY Photoplethysmography
KR20180050948A (en) * 2016-11-07 2018-05-16 삼성전자주식회사 Spectrometer and operation method of spectrometer
US10323384B2 (en) * 2016-12-08 2019-06-18 Caterpillar Inc. Active damping ride control system for attenuating oscillations in a hydraulic actuator of a machine
EP3634528B1 (en) 2017-06-07 2023-06-07 Shifamed Holdings, LLC Intravascular fluid movement devices, systems, and methods of use
US10376149B2 (en) * 2017-07-11 2019-08-13 Colgate-Palmolive Company Oral care evaluation system and process
EP3710076B1 (en) 2017-11-13 2023-12-27 Shifamed Holdings, LLC Intravascular fluid movement devices, systems, and methods of use
EP3746149A4 (en) 2018-02-01 2021-10-27 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
US11246505B2 (en) 2018-11-01 2022-02-15 Biosense Webster (Israel) Ltd. Using radiofrequency (RF) transmission system to find opening in tissue wall
US20220330929A1 (en) * 2019-09-20 2022-10-20 Bard Peripheral Vascular, Inc. Biopsy System having Tissue Sample Impedance Measurement
CN110720924A (en) * 2019-11-27 2020-01-24 河北省中医院 Uterine orifice measuring and displaying instrument for lying-in woman
US20230233244A1 (en) * 2020-07-24 2023-07-27 Apyx Medical Corporation Devices, systems and methods for measuring tissue tightness and performing subdermal coagulation to increase tissue tightness
CA3232720A1 (en) * 2021-09-24 2023-03-30 Jr. Russell L. Case Portable magnetic resonance imager

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689073B2 (en) * 2000-11-13 2004-02-10 Atossa Healthcare Inc. Methods and devices for collecting, handling and processing mammary fluid samples for evaluating breast diseases, including cancer
WO2006116091A2 (en) * 2005-04-21 2006-11-02 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium

Family Cites Families (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE30317E (en) * 1972-11-15 1980-07-01 Hellige Gmbh Method and apparatus for determining the perfusion efficiency factor of animal tissue
US3830224A (en) * 1972-12-19 1974-08-20 Vanzetti Infrared Computer Sys Means for detecting changes in the temperature of the skin
IL53286A (en) * 1977-11-02 1980-01-31 Yeda Res & Dev Apparatus and method for detection of tumors in tissue
US4458694A (en) * 1977-11-02 1984-07-10 Yeda Research & Development Co., Ltd. Apparatus and method for detection of tumors in tissue
USRE32000E (en) 1978-05-22 1985-10-08 B.C.S.I. Laboratories, Inc. Device for use in early detection of breast cancer
US4344440A (en) * 1980-04-01 1982-08-17 Trygve Aaby Microprobe for monitoring biophysical phenomena associated with cardiac and neural activity
JPS5772627A (en) * 1980-10-21 1982-05-07 Tokyo Shibaura Electric Co Apparatus for detecting abnormal cell
CA1196691A (en) * 1982-01-12 1985-11-12 Bradley Fry Reconstruction system and methods for impedance imaging
DE3215529A1 (en) 1982-04-26 1983-10-27 Siemens AG, 1000 Berlin und 8000 München ULTRASONIC APPLICATOR
US4617939A (en) 1982-04-30 1986-10-21 The University Of Sheffield Tomography
JPS59148854A (en) 1983-02-14 1984-08-25 Hitachi Ltd Testing apparatus using nuclear magnetic resonance
JPS59190209U (en) * 1983-06-06 1984-12-17 アロカ株式会社 Breast ultrasound diagnostic equipment
US4689567A (en) * 1984-06-01 1987-08-25 Advanced Nmr Systems, Inc. NMR Fourier imaging from multiple echoes
JPH0341930Y2 (en) 1985-01-31 1991-09-03
US4682594A (en) * 1985-03-11 1987-07-28 Mcm Laboratories, Inc. Probe-and-fire lasers
JPS62247232A (en) * 1986-04-21 1987-10-28 Agency Of Ind Science & Technol Fluorescence measuring apparatus
JP2590317B2 (en) 1986-05-21 1997-03-12 オリンパス光学工業株式会社 Endoscope
US4785806A (en) 1987-01-08 1988-11-22 Yale University Laser ablation process and apparatus
US4751464A (en) * 1987-05-04 1988-06-14 Advanced Nmr Systems, Inc. Cavity resonator with improved magnetic field uniformity for high frequency operation and reduced dielectric heating in NMR imaging devices
US5277730A (en) * 1987-12-16 1994-01-11 At&T Bell Laboratories Methods of recoating spliced lengths of optical fibers
EP0367752B1 (en) 1988-10-31 1993-12-01 AVL Medical Instruments AG Device for determining the concentration of at least one substance in living tissue
SE8900612D0 (en) * 1989-02-22 1989-02-22 Jonas Johansson TISSUE CHARACTERIZATION USING A BLOOD-FREE FLUORESCENCE CRITERIA
JPH0341930A (en) * 1989-07-11 1991-02-22 Toshiba Corp Receiving coil device for mri device
IL91193A (en) * 1989-08-02 1996-01-19 Yeda Res & Dev Tumor detection system
GB8921132D0 (en) 1989-09-19 1989-11-08 Rocket Of London Ltd Diathermy loop
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US6671540B1 (en) 1990-08-10 2003-12-30 Daryl W. Hochman Methods and systems for detecting abnormal tissue using spectroscopic techniques
DE69133603D1 (en) * 1990-10-19 2008-10-02 Univ St Louis System for localizing a surgical probe relative to the head
US5574815A (en) 1991-01-28 1996-11-12 Kneeland; Foster C. Combination cable capable of simultaneous transmission of electrical signals in the radio and microwave frequency range and optical communication signals
JP2615301B2 (en) 1991-04-02 1997-05-28 オリンパス光学工業株式会社 Electronic laparoscope
US7549424B2 (en) 1991-10-18 2009-06-23 Pro Surg, Inc. Method and apparatus for tissue treatment with laser and electromagnetic radiation
US5482041A (en) * 1992-06-05 1996-01-09 Wilk; Peter J. Medical investigation system and related method
US5442290A (en) * 1992-08-04 1995-08-15 The Regents Of The University Of California MRI gradient drive current control using all digital controller
WO1994004938A1 (en) * 1992-08-14 1994-03-03 British Telecommunications Public Limited Company Position location system
US5227730A (en) * 1992-09-14 1993-07-13 Kdc Technology Corp. Microwave needle dielectric sensors
US5334941A (en) * 1992-09-14 1994-08-02 Kdc Technology Corp. Microwave reflection resonator sensors
US5381795A (en) * 1993-11-19 1995-01-17 Advanced Technology Laboratories, Inc. Intraoperative ultrasound probe
US5678565A (en) 1992-12-21 1997-10-21 Artann Corporation Ultrasonic elasticity imaging method and device
JP3276197B2 (en) 1993-04-19 2002-04-22 旭光学工業株式会社 Endoscope
SE501351C2 (en) 1993-05-05 1995-01-23 Harry Nilsson Rotating filter with filter cake removal and delivery means
AU694135B2 (en) * 1993-07-30 1998-07-16 Imcor Pharmaceutical Company Stabilized microbubble compositions for ultrasound
ZA948393B (en) 1993-11-01 1995-06-26 Polartechnics Ltd Method and apparatus for tissue type recognition
US6500112B1 (en) 1994-03-30 2002-12-31 Brava, Llc Vacuum dome with supporting rim and rim cushion
US5704355A (en) 1994-07-01 1998-01-06 Bridges; Jack E. Non-invasive system for breast cancer detection
EP0694282B1 (en) * 1994-07-01 2004-01-02 Interstitial, LLC Breast cancer detection and imaging by electromagnetic millimeter waves
US5829437A (en) 1994-07-01 1998-11-03 Interstitial, Inc. Microwave method and system to detect and locate cancers in heterogenous tissues
GB9418183D0 (en) * 1994-09-09 1994-10-26 Chan Tsing Y A Non-destructive method for determination of polar molecules on rigid and semi-rigid substrates
US5758646A (en) * 1994-09-12 1998-06-02 U.S. Philips Corporation Magnetic resonance imaging method with pulse sequence optimization and device for such method
US5810742A (en) 1994-10-24 1998-09-22 Transcan Research & Development Co., Ltd. Tissue characterization based on impedance images and on impedance measurements
US6560480B1 (en) 1994-10-24 2003-05-06 Transscan Medical Ltd. Localization of anomalies in tissue and guidance of invasive tools based on impedance imaging
WO1996015550A1 (en) * 1994-11-10 1996-05-23 Lawrence Semiconductor Research Laboratory, Inc. Silicon-germanium-carbon compositions and processes thereof
JP3362576B2 (en) 1995-02-10 2003-01-07 ダイキン工業株式会社 Variable displacement piston machine
US5630426A (en) * 1995-03-03 1997-05-20 Neovision Corporation Apparatus and method for characterization and treatment of tumors
US6258576B1 (en) * 1996-06-19 2001-07-10 Board Of Regents, The University Of Texas System Diagnostic method and apparatus for cervical squamous intraepithelial lesions in vitro and in vivo using fluorescence spectroscopy
US5558092A (en) 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
DE19520749C1 (en) 1995-06-07 1996-08-08 Siemens Ag Ultrasonic therapeutic appts. with X-ray transparent source of waves
US5964740A (en) * 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
US5572132A (en) 1995-08-15 1996-11-05 Pulyer; Yuly M. MRI probe for external imaging
US5836311A (en) * 1995-09-20 1998-11-17 Medtronic, Inc. Method and apparatus for temporarily immobilizing a local area of tissue
US5769784A (en) * 1995-11-27 1998-06-23 Hill-Rom, Inc. Skin perfusion evaluation apparatus and method
US5729475A (en) * 1995-12-27 1998-03-17 Romanik, Jr.; Carl J. Optical system for accurate monitoring of the position and orientation of an object
US5727569A (en) * 1996-02-20 1998-03-17 Cardiothoracic Systems, Inc. Surgical devices for imposing a negative pressure to fix the position of cardiac tissue during surgery
EP0791823A3 (en) 1996-02-20 1997-12-10 Hauni Maschinenbau Aktiengesellschaft Method and device for measuring at least one property of a substance
DE19734978B4 (en) 1997-02-12 2013-10-17 Hauni Maschinenbau Ag Method and arrangement for detecting at least one property of a substance
US6004263A (en) 1996-03-13 1999-12-21 Hihon Kohden Corporation Endoscope with detachable operation unit and insertion unit
JPH09243576A (en) 1996-03-13 1997-09-19 Kagaku Gijutsu Shinko Jigyodan Tomographic imaging method and apparatus by two-dimensional time region reflecting method
US5735278A (en) * 1996-03-15 1998-04-07 National Research Council Of Canada Surgical procedure with magnetic resonance imaging
US6258083B1 (en) 1996-03-29 2001-07-10 Eclipse Surgical Technologies, Inc. Viewing surgical scope for minimally invasive procedures
US6296608B1 (en) 1996-07-08 2001-10-02 Boston Scientific Corporation Diagnosing and performing interventional procedures on tissue in vivo
US5851180A (en) * 1996-07-12 1998-12-22 United States Surgical Corporation Traction-inducing compression assembly for enhanced tissue imaging
US5821410A (en) 1996-09-20 1998-10-13 Regents Of The University Of California Scanning tip microwave near field microscope
US5830145A (en) 1996-09-20 1998-11-03 Cardiovascular Imaging Systems, Inc. Enhanced accuracy of three-dimensional intraluminal ultrasound (ILUS) image reconstruction
US6173604B1 (en) * 1996-09-20 2001-01-16 The Regents Of The University Of California Scanning evanescent electro-magnetic microscope
US6311692B1 (en) 1996-10-22 2001-11-06 Epicor, Inc. Apparatus and method for diagnosis and therapy of electrophysiological disease
US6058323A (en) 1996-11-05 2000-05-02 Lemelson; Jerome System and method for treating select tissue in a living being
JPH10234734A (en) * 1996-12-27 1998-09-08 Nohmi Bosai Ltd Ultrasonic probe
US6109270A (en) * 1997-02-04 2000-08-29 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multimodality instrument for tissue characterization
US6086534A (en) * 1997-03-07 2000-07-11 Cardiogenesis Corporation Apparatus and method of myocardial revascularization using ultrasonic pulse-echo distance ranging
US6026323A (en) * 1997-03-20 2000-02-15 Polartechnics Limited Tissue diagnostic system
US5900618A (en) * 1997-08-26 1999-05-04 University Of Maryland Near-field scanning microwave microscope having a transmission line with an open end
US6135968A (en) 1997-09-10 2000-10-24 Scantek Medical, Inc. Differential temperature measuring device and method
DE19841217B4 (en) * 1997-10-27 2005-06-16 Applied Photonics Worldwide, Inc., Reno Apparatus and method for the spectroscopic analysis of human or animal tissue or body fluids
US6071239A (en) * 1997-10-27 2000-06-06 Cribbs; Robert W. Method and apparatus for lipolytic therapy using ultrasound energy
US6375634B1 (en) * 1997-11-19 2002-04-23 Oncology Innovations, Inc. Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy
US20010045832A1 (en) * 1997-11-26 2001-11-29 Kenneth W. Belt Peripheral vascular array
US6055451A (en) * 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
US6093150A (en) * 1997-12-31 2000-07-25 Acuson Corporation Ultrasound otoscope
US6081738A (en) * 1998-01-15 2000-06-27 Lumend, Inc. Method and apparatus for the guided bypass of coronary occlusions
US6331166B1 (en) * 1998-03-03 2001-12-18 Senorx, Inc. Breast biopsy system and method
US6647069B1 (en) 1998-05-01 2003-11-11 Texas Instruments Incorporated Method and apparatus for capacity increase and enhanced communications performance in CATV networks
CA2331644A1 (en) * 1998-05-12 1999-11-18 Neil J. Goldfine Methods for utilizing dielectrometry signals using estimation grids
US6233479B1 (en) * 1998-09-15 2001-05-15 The Regents Of The University Of California Microwave hematoma detector
JP3202696B2 (en) 1998-09-18 2001-08-27 松下電器産業株式会社 Signal processing device
US6144876A (en) 1998-10-23 2000-11-07 Neoprobe Corporation Scanning a radiation source with a count rate output derived with a dynamic window analysis
FI106293B (en) * 1998-11-27 2001-01-15 Planmed Oy Procedures and devices for imaging tissues
CN1341003A (en) 1999-01-26 2002-03-20 牛顿实验室公司 Autofluorescence imaging system for endoscopy
US6090041A (en) * 1999-02-16 2000-07-18 Regents Of The University Of California vacuum actuated surgical retractor and methods
US6397095B1 (en) * 1999-03-01 2002-05-28 The Trustees Of The University Of Pennsylvania Magnetic resonance—electrical impedance tomography
US6546787B1 (en) * 1999-03-25 2003-04-15 Regents Of The University Of Minnesota Means and method for modeling and treating specific tissue structures
DE60031661D1 (en) * 1999-04-20 2006-12-14 Nova Technology Corp METHOD AND DEVICE FOR MEASURING THE WATER IN A SUBSTRATE
US6167297A (en) 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
DE19925468A1 (en) * 1999-06-03 2000-12-07 Hauni Maschinenbau Ag Stray field probe
US6287302B1 (en) 1999-06-14 2001-09-11 Fidus Medical Technology Corporation End-firing microwave ablation instrument with horn reflection device
US6695782B2 (en) * 1999-10-05 2004-02-24 Omnisonics Medical Technologies, Inc. Ultrasonic probe device with rapid attachment and detachment means
GB2357149A (en) 1999-12-08 2001-06-13 Topspin Medical MRI using non-homogeneous static field
US20020120265A1 (en) * 1999-12-23 2002-08-29 Mayo Foundation For Medical Education And Research Symmetric conization electrocautery device
US6530944B2 (en) * 2000-02-08 2003-03-11 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
JP5090600B2 (en) 2000-02-18 2012-12-05 トーマス ジェイ． フォガーティー， Improved device for accurately marking tissues
US6564806B1 (en) * 2000-02-18 2003-05-20 Thomas J. Fogarty Device for accurately marking tissue
US6722371B1 (en) * 2000-02-18 2004-04-20 Thomas J. Fogarty Device for accurately marking tissue
US6728565B2 (en) 2000-02-25 2004-04-27 Scimed Life Systems, Inc. Diagnostic catheter using a vacuum for tissue positioning
US7499745B2 (en) 2000-02-28 2009-03-03 Barbara Ann Karmanos Cancer Institute Multidimensional bioelectrical tissue analyzer
GB2360186B (en) 2000-03-03 2003-05-14 Toshiba Res Europ Ltd Apparatus and method for investigating a sample
US6510336B1 (en) 2000-03-03 2003-01-21 Intra Medical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
GB2360132B (en) * 2000-03-06 2002-04-24 Marconi Caswell Ltd Structure with switchable magnetic properties
GB0005821D0 (en) 2000-03-10 2000-05-03 Black & Decker Inc Coupling method
US6377841B1 (en) * 2000-03-31 2002-04-23 Vanderbilt University Tumor demarcation using optical spectroscopy
US6766185B2 (en) * 2000-05-22 2004-07-20 The Board Of Trustees Of The Leland Stanford Junior University Transmission line techniques for MRI catheter coil miniaturization and tuning
WO2002032335A1 (en) 2000-07-25 2002-04-25 Rita Medical Systems Inc. Apparatus for detecting and treating tumors using localized impedance measurement
JP2002071596A (en) * 2000-08-25 2002-03-08 Yamagata Public Corp For The Development Of Industry Method and instrument for measuring electron spin resonance
ATE408809T1 (en) * 2000-08-31 2008-10-15 Toudai Tlo Ltd OPTICAL BUTTON SENSOR
US6597185B1 (en) * 2000-09-20 2003-07-22 Neocera, Inc. Apparatus for localized measurements of complex permittivity of a material
US6544185B2 (en) * 2000-10-23 2003-04-08 Valentino Montegrande Ultrasound imaging marker and method of use
IL157007A0 (en) 2001-01-22 2004-02-08 Target Technologies Ltd V Ingestible device
US6871086B2 (en) 2001-02-15 2005-03-22 Robin Medical Inc. Endoscopic examining apparatus particularly useful in MRI, a probe useful in such apparatus, and a method of making such probe
WO2002069791A1 (en) * 2001-03-06 2002-09-12 Pendragon Medical Ltd. Method and device for determining the concentration of a substance in body liquid
JP2002263055A (en) 2001-03-12 2002-09-17 Olympus Optical Co Ltd Tip hood for endoscope
JP2002306486A (en) 2001-04-11 2002-10-22 Ge Medical Systems Global Technology Co Llc Production method of ultrasonic probe and ultrasonic probe
EP1407712B1 (en) 2001-07-19 2013-07-10 ARKRAY, Inc. Piercing device
WO2003009752A2 (en) 2001-07-26 2003-02-06 Chad Edward Bouton Electromagnetic sensors for biological tissue applications
US6592520B1 (en) * 2001-07-31 2003-07-15 Koninklijke Philips Electronics N.V. Intravascular ultrasound imaging apparatus and method
US20030045798A1 (en) * 2001-09-04 2003-03-06 Richard Hular Multisensor probe for tissue identification
US7505811B2 (en) 2001-11-19 2009-03-17 Dune Medical Devices Ltd. Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus
US20070255169A1 (en) 2001-11-19 2007-11-01 Dune Medical Devices Ltd. Clean margin assessment tool
US20080154090A1 (en) * 2005-01-04 2008-06-26 Dune Medical Devices Ltd. Endoscopic System for In-Vivo Procedures
US6813515B2 (en) 2002-01-04 2004-11-02 Dune Medical Devices Ltd. Method and system for examining tissue according to the dielectric properties thereof
US20080287750A1 (en) 2002-01-04 2008-11-20 Dune Medical Devices Ltd. Ergonomic probes
US7720532B2 (en) 2004-03-23 2010-05-18 Dune Medical Ltd. Clean margin assessment tool
WO2007083310A2 (en) 2006-01-18 2007-07-26 Dune Medical Devices Ltd. System and method for analysis and treatment of a body tissue
US8116845B2 (en) 2005-08-04 2012-02-14 Dune Medical Devices Ltd. Tissue-characterization probe with effective sensor-to-tissue contact
US8019411B2 (en) * 2002-01-04 2011-09-13 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US7809425B2 (en) 2003-07-24 2010-10-05 Dune Medical Devices Ltd. Method and apparatus for examining a substance, particularly tissue, to characterize its type
US8032211B2 (en) * 2002-01-04 2011-10-04 Dune Medical Devices Ltd. Probes, systems, and methods for examining tissue according to the dielectric properties thereof
US8721565B2 (en) * 2005-08-04 2014-05-13 Dune Medical Devices Ltd. Device for forming an effective sensor-to-tissue contact
US20030199753A1 (en) 2002-04-23 2003-10-23 Ethicon Endo-Surgery MRI compatible biopsy device with detachable probe
US6846290B2 (en) 2002-05-14 2005-01-25 Riverside Research Institute Ultrasound method and system
US6840948B2 (en) * 2002-06-06 2005-01-11 Ethicon-Endo Surgery, Inc. Device for removal of tissue lesions
JP4133013B2 (en) 2002-06-18 2008-08-13 Ｈｏｙａ株式会社 OCT observation probe
JP2006512109A (en) 2002-08-01 2006-04-13 ザ ジョンズ ホプキンズ ユニバーシティ Identification technology of molecular structure using fluorescent light emission, and treatment technology of cell types lined inside the body lumen
US6936003B2 (en) * 2002-10-29 2005-08-30 Given Imaging Ltd In-vivo extendable element device and system, and method of use
JP4334885B2 (en) 2003-02-28 2009-09-30 オリンパス株式会社 Endoscope apparatus and endoscope conduit
US6953288B2 (en) 2003-04-25 2005-10-11 Ceramoptec Industries, Inc. SMA compatible, safe laser connector system
US7725151B2 (en) 2003-06-02 2010-05-25 Van Der Weide Daniel Warren Apparatus and method for near-field imaging of tissue
CN100473336C (en) * 2003-07-24 2009-04-01 沙丘医疗设备有限公司 Method and apparatus for examining a substance, particularly tissue, to characterize type
JP4461763B2 (en) * 2003-10-02 2010-05-12 オムロンヘルスケア株式会社 Visceral fat calculation device
JP4412644B2 (en) * 2003-10-29 2010-02-10 セイコーインスツル株式会社 Cardiodynamic measurement device
US8052676B2 (en) * 2003-12-02 2011-11-08 Boston Scientific Scimed, Inc. Surgical methods and apparatus for stimulating tissue
US7699796B2 (en) * 2004-01-20 2010-04-20 Chuck Olson Ergonomic reflexology device
US7904145B2 (en) * 2004-03-23 2011-03-08 Dune Medical Devices Ltd. Clean margin assessment tool
EP1843696A4 (en) 2005-01-04 2010-01-06 Dune Medical Devices Ltd Endoscopic system for in-vivo procedures
US8449477B2 (en) 2005-03-02 2013-05-28 Dune Medical Devices Ltd. Device and method for transporting and handling tissue
CN101991415B (en) 2005-03-29 2013-04-10 沙丘医疗设备有限公司 Electromagnetic sensors for tissue characterization
US7742796B2 (en) * 2005-10-25 2010-06-22 General Electric Company Breast immobilization device and method of imaging the breast
JP4796831B2 (en) * 2005-12-16 2011-10-19 富士フイルム株式会社 Mammography jig
US20080148277A1 (en) * 2006-12-18 2008-06-19 Nokia Corporation Optimizing calls from a managed runtime environment to microkernel extended functionality

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689073B2 (en) * 2000-11-13 2004-02-10 Atossa Healthcare Inc. Methods and devices for collecting, handling and processing mammary fluid samples for evaluating breast diseases, including cancer
WO2006116091A2 (en) * 2005-04-21 2006-11-02 Epi-Sci, Llc Method and system for detecting electrophysiological changes in pre-cancerous and cancerous tissue and epithelium

Also Published As

Publication number Publication date
US20120123244A1 (en) 2012-05-17
WO2007015255A3 (en) 2009-02-05
US9526460B2 (en) 2016-12-27
EP1919273A2 (en) 2008-05-14
CA2616962A1 (en) 2007-02-08
JP2013031668A (en) 2013-02-14
ES2704827T3 (en) 2019-03-20
JP2009508539A (en) 2009-03-05
US20070032747A1 (en) 2007-02-08
EP1919273B1 (en) 2018-10-10
CN103271718B (en) 2017-07-07
US8116845B2 (en) 2012-02-14
WO2007015255A2 (en) 2007-02-08
CN103271718A (en) 2013-09-04
JP6054106B2 (en) 2016-12-27

Similar Documents

Publication Publication Date Title
EP1919273A4 (en) Tissue-characterization probe with effective sensor-to-tissue contact
GB0508531D0 (en) Sai with ultrasound
AU2005100155A4 (en) Boardsling
AU2005900726A0 (en) GI Probe
AU2005902492A0 (en) Transoesophagael probe
AU2005101012A4 (en) Phoneblock
AU2005100156A4 (en) Auscar
AU2005100875A4 (en) Venti - geni
AU2005100866A4 (en) Infopower
AU2005100821A4 (en) MediDirect
AU2005100778A4 (en) Halta
AU2005100452A4 (en) Sqeg
AU2005100082A4 (en) Mobilus
AU2005100098A4 (en) Vent - A - Loo
AU2005901026A0 (en) Measuring Alertness
AU2005906766A0 (en) Measuring Means
AU2005904848A0 (en) Measuring device
AU2005901901A0 (en) Measuring device
AU2005903843A0 (en) Improved Bullbar
AU2005907287A0 (en) An assay
AU2005904462A0 (en) Device
AU2005904595A0 (en) Rainhead Arrangement
AU2005900029A0 (en) Moonstik
AU2005900990A0 (en) Trade - screen
AU2005900017A0 (en) Medichair

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080228

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

R17D Deferred search report published (corrected)

Effective date: 20090205

RIC1 Information provided on ipc code assigned before grant

Ipc: A61B 17/00 20060101AFI20090220BHEP

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20170804

RIC1 Information provided on ipc code assigned before grant

Ipc: A61B 6/03 20060101ALI20170731BHEP

Ipc: A61B 8/13 20060101ALI20170731BHEP

Ipc: A61B 5/055 20060101ALI20170731BHEP

Ipc: A61B 6/00 20060101ALI20170731BHEP

Ipc: A61B 5/053 20060101ALI20170731BHEP

Ipc: A61B 5/01 20060101ALI20170731BHEP

Ipc: A61B 5/00 20060101AFI20170731BHEP

Ipc: A61B 5/103 20060101ALI20170731BHEP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602006056559

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: A01H0005000000

Ipc: A61B0005000000

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

RIC1 Information provided on ipc code assigned before grant

Ipc: A61B 5/055 20060101ALI20180412BHEP

Ipc: A61B 5/103 20060101ALI20180412BHEP

Ipc: A61B 6/03 20060101ALI20180412BHEP

Ipc: A61B 5/053 20060101ALI20180412BHEP

Ipc: A61B 5/01 20060101ALI20180412BHEP

Ipc: A61B 5/00 20060101AFI20180412BHEP

Ipc: A61B 6/00 20060101ALI20180412BHEP

Ipc: A61B 8/13 20060101ALI20180412BHEP

INTG Intention to grant announced

Effective date: 20180508

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1050277

Country of ref document: AT

Kind code of ref document: T

Effective date: 20181015

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602006056559

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1050277

Country of ref document: AT

Kind code of ref document: T

Effective date: 20181010

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2704827

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20190320

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190110

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190210

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20190111

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602006056559

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

26N No opposition filed

Effective date: 20190711

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190806

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190831

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190831

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20190831

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190806

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190831

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20181010

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20060806

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20210826

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20210826

Year of fee payment: 16

Ref country code: IT

Payment date: 20210820

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20210910

Year of fee payment: 16

Ref country code: GB

Payment date: 20210826

Year of fee payment: 16

Ref country code: DE

Payment date: 20210827

Year of fee payment: 16

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602006056559

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: MM

Effective date: 20220901

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20220806

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220901

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220806

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220831

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20230301

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20230926

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220806

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220807