EP2818420A1 - Method for reliably filling a transport box comprising a plurality of holding compartments using medication packages dispensed by an automated storage with a sequentially dispensing output/input station and output/input station therefor - Google Patents

Abstract

In a method for filling a tray with individual medication portions taken from drug packages provided by an automated warehouse by means of an output / input station, a control unit is provided with a desired filling of trays of the tray in step a) Provided, from which the auszubagernden drug packages and an order of their outsourcing are determined. In step b), a drug package of a given drug is outsourced from the warehouse by being stored (22) by an operator panel on a first takeover point of the output / input station and transported (25) from a first transport device to an output location as soon as the issuing station is free (23). In step c), the drug package is removed from the dispensing station (28). In step d), one or more individual portions are removed from the drug package and introduced respectively into receiving compartments of the tray (29, 30), wherein the operator displays the respective receptacle to be filled and the correct filling is monitored by means of a display device controlled by the control device. In step e), the medicament pack is stored (32) on a re-storage space of the output / input station located in the spatial vicinity of the issuing station and transported by means of a second transport device to a second transfer point, which is accessed by the operating device in order to return the medicament pack to the delivery device Store warehouses (33). The steps b) to e) are repeated for each subsequent drug package until all individual portions are filled according to the target occupancy.

Description

The invention relates to a method for filling a plurality of receiving compartments having open transport boxes (trays) with individual portions of drugs. Further, the invention relates to an automated pharmaceutical dispensing / dispensing station for use in a method of filling a single compartment of medicament having a plurality of storage compartments.

Flat transport boxes (also called trays) with a plurality of open-top receiving compartments, which are preferably arranged in rows and columns in a matrix-like manner, are used, for example, to supply specific predetermined amounts of individual portions of medicaments, such as individual (or even halved) tablets or capsules, for example. a blister machine for producing patient-specific blister packs, ie for automatically filling and packaging medication doses into individual small foil pouches or pouches, in an orderly manner.

Such a blister machine usually has a plurality of storage containers (eg 50 or even a few hundred), each containing large quantities of drug portions, such as tablets or capsules, of frequently needed drugs. Such a blister machine is for example the "Rowa Dose System" of the applicant (see http://www.rowa.de/Rowa-Dose.1072.0.html). The provided in the reservoirs drug portions are automatically removed by computer controlled dosing devices automatically in predetermined number and directed through slides and chutes in collection, each Collecting the collected in a bag or bag drug portions. The collection containers are successively passed to a packaging station at which they are emptied into bags of bags which are still open at first, after which the bags or bags are closed, in particular their film edges are welded. Each bag then contains the contents collected in the sump, which includes, for example, the drug to be taken by a patient at a given time. The time of administration can also be printed on the bag.

In order to be able to deliver medication portions which are less frequently to be dispensed and also not available in the storage containers or else, for example, half tablets into the collecting containers and thus into the bags (blisters), such a blister machine has a device in which such rarer drugs or partial portions ( eg half tablets) can be selectively fully automatically introduced into predetermined collection container. This device, the drug portions in the initially mentioned open transport boxes (trays) in an orderly manner gestell available. In order to control this device, it is necessary for the control computer to know exactly which individual pharmaceutical portions are to be provided in which receptacles of the open transport box (trays). For this purpose, it is again necessary that the manual filling of the trays is monitored in such a way that the correct receiving compartments are filled with the prescribed medicament portions in accordance with a desired filling. Errors in manual filling can occur in particular when a plurality of medicament supply packs are simultaneously provided at the workplace of the filling operator, from which the operator subsequently removes the respectively required number of individual portions and places them in predetermined receiving compartments of the tray. Here, for example, the case may occur that the operator accidentally reaches into the wrong drug supply pack.

The object of the invention is therefore to provide a method for filling the trays, the safety of the correct Filling increases, or to provide a device that supports such a safe filling. In addition, the manual filling should be facilitated and supported.

This object is achieved according to the invention by a method for filling a plurality of storage compartments comprising open trays with individual portions of medicaments with the features of claim 1 or by an output / input station for an automated storage for drug packages for use in a A method for filling a plurality of receiving compartments having open transport boxes (trays) with single portions of medicaments with the features of claim 8 solved.

In the method for filling a plurality of (preferably open-topped) storage compartments having open transport box (also called tray) with individual portions of drugs (for example, tablets and capsules), in which the individual portions of drug packages (for example, commercially available blister boxes or bottles) are provided by an automated warehouse (eg a picking machine) using an output / input station, first (a) a control device (for example, a control computer or a computer network) is provided a nominal filling of the receiving compartments of the transport box from which the packages to be outsourced and a sequence of their outsourcing are determined (this may be carried out in advance or may be ongoing depending on the availability of the packages and other parallel outsourcing operations) , The nominal filling contains information about which medicine portions are to be inserted in the individual storage compartments. Then (b) a drug package containing at least a single portion of a given drug (that is, a still complete or a partially filled drug package), outsourced from the automated warehouse by the drug package from an operator panel (For example, a computer-controlled gripper robot) of the automated warehouse stored on a first takeover point of the output / input station and transported by a first transport device of the output / input station to an output location, as soon as the issuing space is free. Then, (c) the drug package is withdrawn from the dispensing / dispensing station dispensing station (preferably by an operator) and (d) one or more individual portions removed from the dispensed drug package (preferably by the operator) and each into one or more predetermined receiving compartments of the transport box introduced (wherein in each receptacle one or more drug portions can be inserted). In this case, by means of a display device controlled by the control device, the respective receptacle to be filled is displayed (for example by optical and / or acoustic output of the coordinates or position designation of the receiving compartment by means of an output device of a computer or by activating a display arranged directly next to the compartment or by straightening a light spot on the respective compartment, etc.). In addition, the correct filling of the individual portions is monitored by the control device (for example by proximity sensors arranged on each compartment or by computer-aided analysis of an electronic image recorded by the tray). Thereafter, (e) the drug package, if it is partially deflated (ie, for example, still at least a single portion is included, and higher minimum numbers could be specified), on a in the vicinity of the issuing space (ie preferably in the access area of the same operator) arranged for restocking the Stored output and input station and transported from there by means of a second transport device to a second acceptance point, which accesses the operating device (eg gripper robot) of the automated warehouse to store the ("broken") drug package again in the automated warehouse (the control device of the camp Information about the partial emptying of the drug package stores). Finally, (f) steps (b) to (e) are repeated for each subsequent drug package until all individual portions have been filled in accordance with the target occupancy.

This procedure of automated sequential removal and restocking of only one drug supply pack in combination with the supervised removal and insertion into the tray trays has the advantage that erroneous withdrawals from incorrect drug supply packages and incorrect loading of the compartments are avoided.

A preferred embodiment of the method is characterized in that an identification attached to the drug package, for example a barcode or an RFID, is read in step (b) to check the correctness of the withdrawn drug package. This creates additional security.

Preferably, in addition, an identification attached to the drug package, for example a barcode or an RFID, is read in step (d) before or at the time of depositing, in order to check the correctness of the medicament pack to be relocated. This also provides additional security, because the correctness of the pack to be stored again and thus the operator actions can be checked.

A development of the method according to the invention is characterized in that either when removing a drug package from the issuing station or after filling a receiving compartment with the last extracted from a drug package single serving or after placing the partially emptied drug package on the re-storage of the output / input station a the Transport the subsequent drug package to the output location causing signal is generated. For example, the signal causing the transport of the subsequent drug package to the issue place is generated by operating an operator input device. In an alternative embodiment, this will be the transportation of the following Pharmaceutical package to the output location causing signal by triggering a sensor, such as a photoelectric sensor generated.

Another development of the method according to the invention is characterized in that the placement of a drug package on the re-storage space by triggering another sensor, such as a photoelectric sensor, is detected. This allows an automatic triggering of the further transport of the pack to be stored again by the second transport device and an early clearance of the re-storage space for a subsequent restocking.

The pharmaceutical storage automated dispensing / dispensing station dispensing station for use in a method of securely filling a single-portion medicine dispensing open tray comprising a plurality of storage compartments includes a first transport device, a second transport device, and a controller. The first transport device may receive and transport a drug package from an operator device of the automated storage store at a first takeover location to an issue location where the drug package is available for access by an operator. Drive or actuator devices (eg, motors or actuators) of the first transport device drive means for transporting the drug package (eg, conveyor belts) and / or releasing such transport (eg, barriers at the top of a chute or chute) and / or release access to the output location (eg doors). The second transport device can receive a drug package at a re-storage space accessible to an operator and transport it to a second acceptance location in the access area of the operating device, wherein drive or adjusting devices of the second transport device means for transporting the drug package and / or release of such Drive transport. The re-storage space is located in proximity to the issuing location. The control device (for example a control computer) is coupled to the drive or actuating devices of the two transport devices and connected to a detection device for detecting a removal of a drug package from the output location, wherein the control device, after detecting the removal of a drug package from the output location, causes a next If the drug package is already in the first transport device, otherwise causes the operating unit in advance to outsource the drug package to the first place of takeover.

The dispensing / input station according to the invention enables an automated sequential emptying and restocking of only one medicament supply pack at a time, with the advantage that erroneous withdrawals from incorrect medicament supply packs are avoided.

In a preferred embodiment of the dispensing / input station, the driving or actuating devices of the first transporting device drive means for releasing a transport, and the means for releasing comprise an access barrier arranged between the first receiving station and the dispensing station, which further transports a drug package to the dispensing station prevented until the controller releases this transport. This increases the safety of the sequential dispensing of the drug packages. In this embodiment, it is preferably provided that the access barrier is a lock with an inlet-side lock door and an exit-side lock door. Thereby, it is possible to operate the output / input station so that the space containing the output space is always separated from the space containing the acceptance slot. Preferably, the first transport device of the dispensing / input station is arranged in a tunnel which has a wall between the automated storage for drug packages and a Clean room pierces, and the lock closes the tunnel with both the inlet-side lock door and the output-side lock door. This allows a dust-tight separation of a clean room, which contains the output space, from the space of the automated storage rack in which the operating device moves.

In one embodiment, an identification device is provided at the issuing station and / or at the re-storage site, which enables reading of an identification attached to the medicine package. This provides additional security by checking the correctness of the type of drug package located at the point of issue or at the re-storage area.

In a preferred embodiment of the delivery / input station, the first transport device is a first belt conveyor having a first conveyor belt and a drive, and the first transfer station and the exit station are places on the first conveyor belt. This simplifies the structural design, since the means of transport itself makes available the storage areas for the takeover location and the output location. Preferably, the second transport device is a second belt conveyor with a second conveyor belt and a drive and are the re-storage space and the second takeover place on the second conveyor belt. In this embodiment, preferably, the first and the second conveyor belt are arranged parallel to each other and of approximately the same length. The parallel arrangement of counter-rotating flat conveyor belts simplifies the structural design and allows a compact design. The first acceptance point and the second acceptance point are then in a plane and immediately next to each other, which simplifies the control and design of the accessing the HMI device.

In a preferred embodiment of the inventive output / input station, the first and the second conveyor belt are each arranged in a tunnel which penetrates a wall between the automated warehouse for drug packages and a clean room, each with a lock the Closes the tunnel with both an entry-side lock door and an exit-side lock door. This embodiment combines the mentioned advantages of the parallel band arrangement with those of the lock design.

Advantageous and / or preferred embodiments of the invention are characterized in the subclaims.

• Figur 1 eine schematische Frontansicht eines Ausführungsbeispiels der erfindungsgemäßen Ausgabe-/EingabeStation mit nebeneinander angeordnetem Ausgabeplatz und Wiedereinlagerungsplatz;
• Figur 2 eine schematische Draufansicht des in Figur 1 gezeigten Ausführungsbeispiels der erfindungsgemäßen Ausgabe-/Eingabe-Station;
• Figur 3 eine schematische Schnittansicht der in Figur 1 gezeigten Ausgabe-/Eingabe-Station entlang der Linie A-A; und
• Figur 4 eine schematische Darstellung des Verfahrensablaufs einer Ausführungsform des erfindungsgemäßen Verfahrens.

The invention will be described in more detail with reference to a preferred embodiment shown in the drawings. In the drawings show:

• FIG. 1 a schematic front view of an embodiment of the output / input station according to the invention with juxtaposed output slot and re-storage space;
• FIG. 2 a schematic plan view of the in FIG. 1 shown embodiment of the output / input station according to the invention;
• FIG. 3 a schematic sectional view of in FIG. 1 shown output / input station along the line AA; and
• FIG. 4 a schematic representation of the process flow of an embodiment of the method according to the invention.

The FIGS. 1 to 3 show schematic views of an embodiment of the inventive output / input station 1 of an automated storage for drug packages. The dispensing / input station 1 has transport means for dispensing drug packages paged out of the warehouse and for re-storing drug packages into the warehouse, the transport means being through a wall 3 of a housing or a panel of the automated warehouse (order picking machines) and through a wall 2 are passed to a clean room. The outsourced drug packages are provided as reservoirs for drug portions in the clean room of an operator who removes individual tablets or capsules (medication portions) from these medicament packs successively and, for example, manually unpacks them into receiving compartments of a plurality of such Trays containing open transport boxes (trays) inserts. This filling of the trays takes place in a clean room, so that as little dirt particles get into the receiving compartments of the tray.

FIG. 1 shows a schematic plan view of the pureraumseitige front side of the output / input station 1. The output / input station 1 comprises a transport devices receiving channel, which is arranged in an opening of the wall 2 and an opening of the outer wall 3 of the picking machine. In FIG. 1 can be seen the rectangular channel, the two juxtaposed conveyor belts 4 and 5 (one sees in the figure, the front sides of the conveyor belts on the pulleys) contains.

FIG. 2 shows a schematic plan view of the output / input station 1. The wall 2 separates the in FIG. 2 below the wall 2 shown clean room of the in FIG. 2 Above the wall 2 shown space that receives the order picking machine. On the clean room side can be seen the conveyor belts 4 and 5, the conveyor belt 4 resting drug packages transported from a first takeover point 8 within the housing of the order picking machine to an issuing space 6 on the clean room side, while the conveyor belt 5 drug packages on a re-storage space 7 on the clean room side have been placed, transported to a second takeover point 9 within the housing of the order picking machine. A (not shown) HMI device of the order picking machine, in particular a gripper robot, on the one hand can store individual drug packages on the first takeover place 8 on the first conveyor belt 4 and on the other hand take medicine packs from the second takeover point 9 on the second conveyor belt 5. The two conveyor belts 4 and 5 are arranged in parallel at the same height next to each other and can be moved independently in opposite directions. On the side of the interior of the picking machine, the conveyor belts 4 and 5 are covered by a housing that rests tightly against the recess in the wall 2. In addition, the channel of the output / input station 1, in which the conveyor belts 4 and 5 are arranged, provided with a lock, so that the clean room can be separated from the space of the picking robot. For each of the two conveyor belts 4 and 5, there is a lock gate on the side of the picking robot and a cleanroom facing lock gate. Between the conveyor belts 4 and 5 is also a partition that divides the channel. In FIG. 2 is designated by the reference numeral 10, a front inside the picking robot arranged lock gate.

FIG. 3 shows a schematic sectional view through the output / input station 1 along the line AA according to FIG. 1 , It can be seen here that the output / input station 1 comprises a control device arranged in the interior of the housing 3 of the automatic communication system and including a transport channel receiving the conveyor belts (shown the conveyor belt 4), the transport channel initially having an opening in the wall 3 of FIG Picking and then penetrates a recess in the wall 2 to the clean room. The conveyor belt 4 is driven by a drive motor 12. It can be seen at the ends of the conveyor belt, the pulleys. On the top side of the conveyor belt 4 is located on the clean room side of the delivery point 6 and - within a lock chamber - on the side of the order picking the first takeover 8. Two lock gates 10 and 11 close the channel above the conveyor belt 4. A first lock gate 10 closes the lock chamber on the side of the picking machine and a second lock gate 11 closes the lock chamber on the output side to the clean room. In the arranged above the transport channel space for receiving control devices of the output / input station 1, inter alia, the drives 13 for the sluice gates 10 and 11 are arranged.

The work station for filling the trays, not shown in the figures, is arranged immediately adjacent to the dispensing station 6 and the re-storage station 7, so that the operator inserting the medicament portions into the receiving compartments of the trays can access the dispensing station 6 or the restacking station 7. There are also both at the issuing station 6 and at the re-storage place 7 reading devices (for example scanners), with which on the drug packages applied identification means (for example, bar codes) can be read. Thus, the user can check their identity when removing a drug package from the issuing station 6, for example, scan a barcode. Likewise, when returning a drug package to the re-storage site 7, the operator may again read its identifier (eg, bar code) to allow the controller to check the correctness of the package to be relocated. In this way, the control device can check whether the operator has actually returned the medicament pack previously removed from the dispensing station 6 to the restacking station 7 after the removal of the medicament portions to be inserted into the receiving compartments of the tray. If this is not the case, the control device generates a warning signal and requests for correction before the issue of subsequent drug packages is initiated.

The following is based on FIG. 4 a preferred embodiment of the method according to the invention for filling a plurality of receiving compartments having open transport boxes (trays) are described with single portions of drugs.

In a first step 20, data describing a nominal filling of a tray with individual portions of medication is sent to the control computer of the picking machine. These data indicate, for example, in which storage compartments which type of tablets or capsules are to be filled. Preferably, the receiving compartments of the tray are arranged in a matrix of rows and columns and preferably the data characterizing the desired filling comprise the coordinates of these receiving compartments.

Subsequently, the control computer determined in step 21 based on the desired filling a first auszulagernde pack. The selection of the first drug package may depend on the transport route and location of the package or even which Pharmaceutical species in a first compartment of the matrix of trays of the tray to be stored. The control computer can also pre-determine the full sequence of the auzulagernden drug packages on the basis of the nominal filling and then by storing appropriate information in designated memories of the control computer ensure that the so reserved drug packages are not outsourced for other purposes from the camp can.

Subsequently, in step 22, a first pack is outsourced by the operating device and stored on the first takeover point 8. For this purpose, if necessary, the lock gate 10 is opened on the side of the interior of the order picking machine and closed again after the first package has been deposited. In step 23 it is checked whether the storage space 6 is free. When issuing the first pack, this question is of course affirmed. In subsequent outsourcing further packages this query ensures that an activation of the conveyor belt 4 takes place only when the previous drug package has been removed from the dispensing station 6. In a subsequent query 24 is checked whether a still removed by the operator from the dispensing station 6 drug package, from which he should take drug portions for restocking, that is for storage on the re-storage space 7, is pending, that is, whether such a pack is not yet again has been stored on the re-storage space 7. If this question is answered in the affirmative, that is, if a previously outsourced drug package has not yet been placed on the re-storage site, the control computer waits, so that no further transport of the subsequent drug package stored on the first take-off location 8 takes place.

If, however, the question is answered in the negative in step 24, that is to say if the preceding medicament pack has already been deposited in the re-storage location, the method continues with step 25, in which the medicament pack is transported from the first transfer point 8 to the delivery point 6. There it is then ready for removal by the operator.

Without waiting for removal by the operator, the process continues with query step 26, which checks to see if the package just transported to the dispensing location is the last package needed for the target filling. If yes, the outsourcing and issuing ends at the issuing place. However, if this is negated, the method returns to step 21, in which the subsequent pack to be outsourced is determined. If the sequence of the packages to be outsourced has already been determined beforehand, the next package of the sequence for removal is simply provided here. The method then proceeds again to step 22, in which the subsequent package is removed from the automated warehouse by the operating device and stored on the first acceptance point 8. Subsequently, in step 23, it is again asked whether the delivery location is free. This is negated, for example, if the operator has not yet removed the package previously transported in step 25 to the delivery location 6.

The loop in the upper half of the representation of the figure ensures that already for the transport of a subsequent auszulagernden pack is taken while the previously outsourced pack is still on the delivery point 6. However, the conveyor belt 4 is only operated again when the discharge station has been previously emptied by removing the pack.

In the lower half of the FIG. 4 is the process that begins with the removal of a pack from the delivery point 6 by the operator. This removal in step 28 is temporally decoupled from the transport step 25, which is indicated by a dashed arrow 36. The removal of the pack in step 28 of course takes place after the transport of the pack to the delivery point 6; However, it may take an indefinite time between the transport of the package to the delivery point 6 and the removal of the pack.

In step 29, the operator removes a drug portion, such as a tablet or capsule, from the drug package removed from the dispensing station 6. At the same time, the control computer displays the receptacle of the waiting tray into which this medication portion is to be inserted. Since the control computer monitors both the transportation and the removal of the particular drug package and also monitors the filling of portions in the receiving compartments with the aid of sensors, the control computer also knows which tray of the tray at the next time Medicament portion is inserted. As already stated above, the display of the respective receiving compartment of the tray can be done in the simplest case by a visual or audible output on a screen or by means of a loudspeaker. Preferably, however, the selected receptacle is directly marked, for example, by activating an optical display visible to the operator adjacent or below the receptacle. If the tray is in a predetermined orientation in a given place, the display can also be done by directing a light spot on the selected receiving compartment. The operator then inserts the medication portion in the indicated tray of the tray, which in turn is detected by means of suitable sensors by the control computer.

In step 30, it is asked whether another drug portion from this outsourced drug package should be placed in the same or another receptacle of the tray. If this is the case, step 29 is executed again.

If all the drug portions to be loaded from the outsourced drug package into the tray to be loaded have been filled in, ie no further tablet is to be taken from this pack, the procedure continues with query 31. Here is asked if the pack is empty. The control computer recognizes this automatically because it tracks the respective level of the pack. In addition, to increase security, it may be provided that the operator makes an entry as soon as he determines that the drug package is empty. If this is a contradiction between this input of the operator and the tracked by the control computer level the drug package found, so a corresponding error signal can be issued. The user can then be asked to check the facts in more detail.

If it is determined in step 31 that the pack is empty (arrow 35), then the process continues in step 34 with the query as to whether the last paged pack is the last pack required for the desired fill. If so, the procedure ends. If this is not the case, it can be assumed that the upper half of the FIG. 4 already shown procedure has ensured that the subsequent drug package has been transported to the dispensing station 6. Then the procedure in the lower half of FIG. 4 continued with step 28, namely the removal of the pack by the operator.

If it is determined in step 31 that the pack is not empty, then the method continues with step 32, namely with the return of the pack on the re-storage space 7. Here are also several variants conceivable. For example, as the fill level is tracked by the control computer, the user may be prompted to return the pack to the re-storage space and, if necessary, to have the barcode scanned. On the other hand, the user can always put the pack itself back to the re-storage space, with the help of suitable sensors, this process is detected by the control computer. The control computer then checks to see if the package placed on the re-storage site 7 is the correct package.

The method then proceeds to step 33 where the package placed on the re-storage yard 7 is transported from the conveyor belt 5 to the second transfer yard 9. In turn, the lock gates are operated in a corresponding manner. From the second acceptance point 9, the control unit of the automated warehouse removes the package (which is partially emptied) and stores it in a suitable place. Of course, the control computer stores in association too the storage location of this pack also the level of the partially emptied pack.

After step 33, the process is continued again with query 34 described above. In alternative embodiments, the step 34 and the subsequent steps can also be carried out after a return of the pack has been detected in the restocking 7 in step 32. Already during the return transport to the second acceptance point and the restoring by the operating device in step 33, the step 28 and optionally the subsequent steps 29 and 30 can be carried out in this way, which shortens the overall process. In this case, in turn, a query must be provided, which avoids that a further drug package is returned to the restocking 7, before the previously launched there pack has been removed at the second takeover point 9 of the HMI device.

Numerous alternative embodiments are conceivable within the scope of the inventive concept. Instead of arranging the sluice gates on the side of the order picking these can also be arranged on the side of the clean room. For example, both the issuing space 6 and the re-storage space 7 may be completely enclosed by walls and be accessible to the operator only after opening the doors provided on the front. Instead of the conveyor belts, it is also possible, for example, to use chutes as a transport device, it being possible to provide barriers along the chutes, which can prevent or release further slippage of the medicament packs. It is essential, however, that the issuing station 6 and the restocking station 7 are in close spatial proximity to one another, that is to say they can be accessed simultaneously by the operator who is filling the trays.

Claims (16)

A method for filling a plurality of receiving compartments having open transport boxes (trays) with individual portions of medicines,
wherein the individual portions are taken from drug packages provided by an automated warehouse using an output / input station (1), wherein: a) a setpoint filling of the receiving compartments of the transport box is provided to a control device (20) from which the medicament packs to be outsourced and an order of their removal are determined (21), b) a medicament pack containing at least a single portion of a predetermined drug, is outsourced from the automated warehouse by the drug package from an operating unit of the automated warehouse on a first takeover place (8) of the output / input station (1) stored (22) and is transported (25) from a first transport device (4) of the output / input station (1) to an issuing station (25) as soon as the issuing station (6) is free (23), c) the medicament pack is taken from the dispensing station (6) of the dispensing / input station (1) (28), d) one or more individual portions are taken from the removed medicament pack by an operator and are each introduced into one or more predetermined receiving compartments of the transport box (29, 30),
wherein by means of a display device controlled by the control device to the operator, the respectively to be filled receptacle is displayed, and
wherein the correct filling of the individual portions is monitored by the control device, e) the medicine package, if partially emptied, is located in close proximity to the place of dispensing (6) arranged re-storage space (7) of the output / input station (1) stored (32) and from there by means of a second transport device (5) to a second transfer point (9) is transported, which accesses the control unit of the automated warehouse to the drug package again to be stored in the automated warehouse (33), and f) the steps b) to e) are repeated for each subsequent drug package until all individual portions have been filled in accordance with the target occupancy. A method according to claim 1, characterized in that an attached to the drug package identification, such as a bar code or an RFID, in step b) is read to check the correctness of the withdrawn drug package. A method according to claim 1 or 2, characterized in that an attached to the drug package identification, such as a bar code or RFID, in step d) before or during the reading is read to check the correctness of the reinserted drug package. Method according to one of claims 1 - 3, characterized in that either when removing a drug package from the dispensing station (6) - or after filling a receptacle with the last extracted from a drug package single serving - or after placing the partially emptied medicine package on the re-storage space (7) of the output / input station (1)
a signal causing the transport of the subsequent medicament pack to the dispensing station (6) is generated. A method according to claim 4, characterized in that the transport of the subsequent drug package to the Issuing station (6) causing signal by pressing an operator input device is generated. A method according to claim 4, characterized in that the transport of the subsequent drug package to the output location (6) causing signal by triggering a sensor, such as a photoelectric sensor, is generated. Method according to one of claims 1 - 6, characterized in that the placement of a drug package on the re-storage space (7) by triggering a further sensor, such as a light barrier is detected. An automated pharmaceutical dispensing dispensing / dispensing station (1) for use in a method of filling a single-portion pharmaceutical dispensing tray having a plurality of receiving compartments, comprising: a) a first transport device (4) which can receive a medicament pack from an operating device of the automated rack store at a first take-over location (8) and transport it to an issue place (6) at which the medicament pack is available for access by an operator,
drive or actuating devices (12, 13) of the first transport device (4) driving means for transporting the medicament pack and / or for releasing such transport and / or for releasing access to the issuing station, b) a second transport device (5) which can receive a medicament pack at a restocking place (7) accessible to an operator and transport it to a second transfer point (9) in the access area of the operating device,
wherein driving or adjusting devices of the second transport device means for transporting the Drug package and / or to release such transport,
wherein the re-storage space (7) is arranged in spatial proximity to the output location (6), and c) a control device coupled to the drive or actuating devices of the two transport devices (4, 5), which is connected to a detection device for detecting a withdrawal of a drug package from the dispensing location, the control device, after detecting the removal of a drug package from the dispensing location (6 ) causes a next drug package to be transported to the issuing station (6), if the drug package is already in the first transport device (4), otherwise the operator device prompts to outsource the drug package to the first accept point (8). Dispensing / input station according to claim 8, characterized in that the drive or adjusting devices (12, 13) of the first transport device (4) drive means for releasing a transport and the means for releasing a between the first takeover place (8) and the access point (6) arranged access barrier (11), which prevents further transport of a drug package to the issuing station (6) until the control device releases this transport. Dispensing / input station according to claim 9, characterized in that the access barrier is a lock with an inlet-side lock door (10) and an exit-side lock door (11). Dispensing / input station according to claim 10, characterized in that the first transport device (4) of the dispensing / input station is arranged in a tunnel having a wall (3, 2) between the automated drug package store and a clean room pierces, and the Lock the tunnel with both the inlet-side lock door (10) and with the output-side lock door (11) closes. Issuing / input station according to one of claims 8 - 11, characterized in that at the issuing station (6) and / or at the re-storage place (7) an identification device is provided which allows a reading attached to the drug package identification. Dispensing / input station according to one of claims 8 - 12, characterized in that the first transport device is a first belt conveyor with a first conveyor belt (4) and a drive (12) and the first take-off place (8) and the output place (6 ) Places on the first conveyor belt (4) are. Dispensing / input station according to one of claims 8-13, characterized in that the second transport device is a second belt conveyor with a second conveyor belt (5) and a drive and the re-storage space (7) and the second take-over place (9) places the second conveyor belt (5). Dispensing / input station according to one of claims 13-14, characterized in that the first (4) and the second (5) conveyor belt are arranged parallel next to one another and of approximately the same length. Dispensing / input station according to claim 15, characterized in that the first and second conveyor belts (4, 5) are each arranged in a tunnel which pierces a wall (2, 3) between the automated drug package store and a clean room , wherein in each case a lock closes the tunnel both with an inlet-side lock door and with an output-side lock door.

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