US20020091439A1 - Graft assembly having support structure - Google Patents

Graft assembly having support structure Download PDF

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Publication number
US20020091439A1
US20020091439A1 US10/066,436 US6643602A US2002091439A1 US 20020091439 A1 US20020091439 A1 US 20020091439A1 US 6643602 A US6643602 A US 6643602A US 2002091439 A1 US2002091439 A1 US 2002091439A1
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United States
Prior art keywords
graft
superior
inferior
capsule
lumen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US10/066,436
Inventor
Steve Baker
Michael Dake
David Dillow
Arnold Escano
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Lifeport Sciences LLC
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Individual
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23408154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20020091439(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Priority to US10/066,436 priority Critical patent/US20020091439A1/en
Publication of US20020091439A1 publication Critical patent/US20020091439A1/en
Assigned to ACACIA RESEARCH GROUP LLC reassignment ACACIA RESEARCH GROUP LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ENDOVASCULAR TECHNOLOGIES, INC.
Assigned to LIFEPORT SCIENCES LLC reassignment LIFEPORT SCIENCES LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ACACIA RESEARCH GROUP LLC
Abandoned legal-status Critical Current

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Definitions

  • This invention relates to a system for implanting a prosthesis, and more particularly, to a delivery catheter for placing a graft having an attachment system within a corporeal lumen.
  • a prosthesis for intraluminal repair of a vessel In intraluminal vessel repair, the prosthesis is advanced intraluminally through the vessel to the repair site using a delivery catheter and deployed within the vessel so that the prosthesis traverses the diseased portion to thereby repair the vessel.
  • thoracic aneurysms differ from other aortic aneurysms in several respects.
  • concerns specific to thoracic aneurysms that are not evident in the repair of other types of aortic aneurysms.
  • the size and shape of the thoracic aneurysms differ and are often more varied than other types of aortic aneurysms
  • thoracic aneurysms are often close to what are typically called the great arteries, such as the left subclavian artery, or may be found to occur proximal to the celiac trunk.
  • These lumens which branch away from the thoracic region of the aorta, are critical to the body's circulatory system and carry high volumes of blood to various parts of the body. Consequently, these lumens generally cannot be occluded by a prosthesis used to intraluminally repair a thoracic aneurysm unless additional procedures are performed to bypass the occluded lumen.
  • thoracic aneurysms have diameters that are typically larger and have shapes perhaps more variable than other aortic aneurysms.
  • the average neck diameter of thoracic aneurysms is on the order of 34-36 mm and the average length approximately 10 cm with a range of 5-16 cm.
  • the superior neck of thoracic aneurysms are often at a different angle from that of the inferior neck.
  • thoracic aneurysms may be fusiform in shape, or comprise giant penetrating ulcers.
  • the attachment system of a graft for repairing a thoracic aneurysm must be sufficient to prohibit migration of the graft. It is also to be noted that there is typically a lack of calcification in the area of thoracic aneurysms. Consequently, the attachment systems of grafts for repairing thoracic aneurysms generally need not be placed within the lumen with forces overcoming such hardening of tissue.
  • a graft and a delivery catheter system therefor wherein the graft is designed specifically to repair thoracic aortic aneurysms and the delivery system functions to precisely position a graft within an aorta to thereby completely repair the thoracic aneurysm.
  • the graft is to be configured to conform to the various possibilities of shapes of the thoracic aneurysm and to have an attachment system which effectively affixes the graft within the aorta.
  • the delivery catheter is to effectively operate within the unique anatomical constraints of the thoracic portion of the aorta. The present invention accomplishes these goals.
  • the present invention provides a new and improved graft and delivery catheter and a novel method for their use in repairing a lumen.
  • the graft is configured for repairing a diseased condition of the lumen.
  • the delivery catheter is configured to introduce the graft within or between vessels or corporeal lumens of an animal, such as a human, and to facilitate the deployment of the graft at the repair sites.
  • the present graft has a diameter that is larger than that of conventional grafts so that relatively larger lumens may be repaired and its walls are thinner to facilitate packing it within the delivery catheter.
  • the attachment system of the present graft is expandable and is stiffer and has hooks with greater angles from radial than conventional attachment systems. Also, in addition to being secured to the ends of the graft, the attachment system is secured by its apices to the graft to prevent relative motion of the attachment system and graft. Further, the novel attachment system of the present graft enables it to self expand quickly and forcefully without the aid of a balloon catheter as well as enables it to securely hold the graft within lumens carrying high volume of blood.
  • the present delivery catheter includes structure for quickly deploying the graft within the lumen to be repaired. Further, by not employing a balloon catheter, the delivery catheter may be utilized to repair lumens located near the heart without placing undue stress on the heart and is configured for packing a larger diameter graft within the delivery catheter. Additionally, the delivery catheter is configured to hold the attachment systems affixed to the ends of the graft within capsules and by not placing the entire graft within a single capsule, larger diameter grafts may be packed within the delivery catheter. Moreover, the delivery catheter is longer which enables it to reach an aortic arch and employs a novel releasing system cooperating with the capsules which, in conjunction, operate to facilitate loading as well as deployment of the graft.
  • the releasing system includes a release wire cooperating with releasable ties attached to the exterior of the graft to maintain the attachment systems of the graft in a collapsed configuration and to facilitate the expansion of the attachment systems so that they properly and quickly engage the walls of the lumen.
  • the present invention provides a prosthesis or graft for intraluminal placement in a fluid conducting corporeal lumen.
  • the graft is hollow and has a pre-selected cross-section, length and wall thickness.
  • the graft is deformable to conform substantially to the interior surface of the corporeal lumen or other body part to be repaired.
  • the midsection of the graft may be crimped to resist kinking and facilitate placement accuracy and may comprise radiopaque markers attached along its length to help orient the graft using fluoroscopy or X-ray techniques. Tufts of yarn are sewn into the graft at its ends to facilitate healing and placement of the graft within the corporeal lumen.
  • the graft comprises woven polyester or another material suitable for permanent placement in the body such as PTFE.
  • the superior and inferior ends of the graft are positioned within the corporeal lumen and the graft is configured such that it traverses the diseased or damaged portion of the vessel.
  • attachment systems are secured to the superior and inferior ends of the graft.
  • the preferred attachment system includes wall engaging members.
  • the wall engaging members of the superior attachment systems are angled toward the inferior end of the graft.
  • the wall engaging members of the inferior attachment systems are angled toward the superior end of the graft.
  • the angles of both the superior and inferior wall engaging members are in the range of 60-80° from radial.
  • the wall engaging members of both attachment systems have sharp tips for engaging the corporeal lumen wall.
  • the preferred attachment systems are formed into a staggered V-shape lattice or framework, the apices of which comprise helical torsion springs.
  • the frame of the attachment systems allows for elastic radial deformation resulting in a spring-like effect when a compressed attachment system is allowed to expand as the graft is released from the capsules, and by having a high stiffness, they function to quickly and forcefully seat the graft within the lumen.
  • the delivery catheter of the present inventor is flexible and includes an elongate cylindrical jacket overlaying a superior capsule assembly and an inferior capsule assembly, each of which are adapted to releasably retain an end of the graft.
  • the superior capsule assembly further includes an elongated flexible conical-shaped or tapered nose cone adapted to facilitate the advancement of the delivery catheter through a patient's vasculature.
  • Attached at the most proximal end of the inferior capsule assembly is an elongate outer shaft, comprising an inferior capsule catheter, which is adapted to receive a multi-lumen inner shaft.
  • the lumens of the inner shaft are conduits for a guidewire, one or two release wires, an anti-elongation wire and a control wire that cooperates with the superior capsule assembly.
  • Attached to the inner shaft and distal to the outer shaft/inferior capsule assembly junction is a conical-shaped knob that cooperates with the superior capsule assembly.
  • Also attached to the inner shaft is an anti-elongation wire that functions to minimize elongation of the inner shaft during deployment of the graft.
  • the jacket is capable of moving relative to the rest of the catheter and thus can be withdrawn, thereby exposing the capsules and graft.
  • the capsules can be caused to move relative to the inner shaft and the structure attached thereto, which, in conjunction with the operation of the releasing system, thereby causes the deployment of the graft within a lumen.
  • the length of the delivery catheter is sufficient for use in reaching the thoracic portion of the aorta and has a diameter suited for encasing a graft for use in repairing a thoracic aneurysm.
  • Deployment of the graft comprises a series of steps which begins with introducing the delivery catheter into the corporeal lumen using well known surgical techniques.
  • the delivery catheter is manipulated so that the graft retained by the superior and inferior capsule assemblies is positioned at a desired location within the corporeal lumen.
  • the jacket is retracted and the superior and inferior capsule assemblies are removed from the graft to expose the superior and inferior attachment systems of the graft.
  • the releasing system is employed to thereby allow the attachment systems self-expand and seat the graft within the lumen.
  • Two methods are contemplated for placing the graft within a lumen.
  • the jacket is moved proximally to expose the graft retained by the superior and inferior capsules.
  • the superior capsule assembly is moved distally to expose the superior end of the graft and the inferior capsule assembly is moved proximally to expose the inferior end of the graft.
  • the releasing system is then employed to release the superior attachment system, thereby allowing the superior attachment system to affix the superior end of the graft within the lumen.
  • the releasing system is employed to release the inferior attachment system to thereby allow the inferior attachment system to affix the inferior end of the graft within the lumen.
  • these steps are reordered so that the inferior end of the graft is first seated within the lumen and thereafter, the superior end is seated.
  • FIG. 1 is a top plan view of the delivery catheter and graft incorporating the present invention.
  • FIG. 2 is a top plan view of a an anti-elongation wire of the present invention.
  • FIG. 3 is a top plan view of a release wire of the present invention.
  • FIG. 4 is a top plan view of a guidewire to be used with the delivery catheter of the present invention.
  • FIG. 5 is a top plan view of an inner catheter assembly of the present invention.
  • FIG. 6 is a top plan view of a superior capsule assembly, control wire, hypotube and control wire handle assembly of the present invention.
  • FIG. 7 is a top plan view of an inferior capsule and capsule catheter of the present invention.
  • FIG. 8 is a top plan view of a capsule jacket assembly of the present invention.
  • FIG. 9 is a top plan view of a graft for use with the delivery catheter of the present invention.
  • FIG. 10 is a cross-sectional view taken along the line 10 - 10 of FIG. 1.
  • FIG. 11 is an alternate embodiment of the view depicted in FIG. 10.
  • FIG. 12 is a partial cross-sectional view of the inferior capsule, superior capsule and capsule jacket assemblies and the anti-elongation wire, release wire and graft.
  • FIG. 13 is an enlarged perspective view showing a presently preferred embodiment of the distal end of the control wire, superior cap insert, superior cap and nose cone.
  • FIG. 14 is an enlarged cross-sectional view of the superior capsule assembly.
  • FIG. 15 is a cross-sectional view taken along the line 15 - 15 of FIG. 14.
  • FIG. 16 is a partial cross-sectional view of the control wire and control handle mechanism of FIG. 1.
  • FIG. 17 is a cross-sectional view taken along the line 17 - 17 of FIG. 16.
  • FIG. 18 is a cross-sectional view taken along the line 18 - 18 of FIG. 16.
  • FIG. 19 is a cross-sectional view taken along the line 19 - 19 of FIG. 16.
  • FIG. 20 is a cross-sectional view taken along the line 20 - 20 of FIG. 16.
  • FIG. 21 is a partial cross-sectional view of the graft and attachment system of the present invention.
  • FIG. 22 is a cross-sectional view taken along the line 22 - 22 of FIG. 21.
  • FIG. 23 is an enlarged perspective view showing a superior attachment system.
  • FIG. 24 is an enlarged perspective view showing an inferior attachment system.
  • FIG. 25 is a perspective view showing an alternate embodiment of the graft.
  • FIG. 26 is an enlarged perspective view showing an alternate embodiment of the wall engaging members of the attachment system.
  • FIG. 27 is an enlarged perspective view showing an alternate embodiment of the wall engaging member of the present invention.
  • FIG. 28 is an enlarged perspective view showing another view of the alternate embodiment of FIG. 27.
  • FIG. 29 is a perspective view showing another embodiment of the graft.
  • FIG. 30 is a cross-sectional view of the graft depicted in FIG. 29.
  • FIG. 31 is a perspective view showing yet another embodiment of the graft.
  • FIG. 32 is a cross-sectional view of the graft depicted in FIG. 31.
  • FIG. 33 is a partial cross-sectional view of the delivery catheter and graft, illustrating a releasing system of the delivery catheter.
  • FIG. 34 is a cross-sectional view taken along the line of 34 - 34 of FIG. 33.
  • FIG. 35 is a partial cross-sectioned view of the delivery catheter and graft, illustrating another embodiment of the releasing system of the delivery catheter.
  • FIG. 36 is a partial cross-sectional view of the delivery catheter and graft positioned within the corporeal lumen.
  • FIG. 37 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 33, wherein the capsule jacket has been retracted proximally relative to the delivery catheter.
  • FIG. 38 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 34, wherein the superior capsule assembly has been removed from the superior end of the graft.
  • FIG. 39 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 35, wherein the inferior capsule has been removed from the inferior end of the graft.
  • FIG. 40 is partial cross-sectional view of the delivery catheter and graft shown in FIG. 36, wherein the release system has been used to facilitate emplacement of the superior attachment system within the corporeal lumen.
  • FIG. 41 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 37, wherein the release system has been utilized to facilitate emplacement of the inferior attachment system within the corporeal lumen.
  • the invention is embodied in a thoracic graft and a delivery catheter therefor.
  • One of the novel features of the present invention is the attachment system of the graft which operates to securely affix the graft within a lumen without the aid of a balloon catheter.
  • Another novel feature of the present invention is the releasing system which functions to release the attachment systems of the graft once the graft has been advanced within the vasculature of the patient to the repair site.
  • the graft is comprised of a monoluminal tubular member having superior and inferior extremities. Expandable attachment systems are secured to the superior and inferior ends of the tubular member. The attachment systems are provided with wall engaging members which are covered by the inferior and superior capsule assemblies.
  • the delivery catheter includes a plurality of elongate components which are configured coaxially so that relative movement between them provides for deployment of the graft.
  • the delivery catheter 50 is shown in FIGS. 1 - 8 .
  • the delivery catheter 50 includes an inner catheter assembly 51 , which is coaxially disposed within an inferior capsule catheter 52 , which is coaxially disposed within the capsule jacket 53 .
  • a superior capsule assembly 90 is disposed about the inner catheter.
  • Attached to the inferior capsule catheter 52 is an inferior capsule assembly 130 .
  • the inferior capsule assembly 130 and the superior capsule assembly 90 are used to contain the attachment systems of the graft 55 .
  • a control wire assembly 54 (see FIG. 6) is coaxially disposed within one of a plurality of lumens of an inner shaft 61 included in the inner catheter assembly 51 and is configured to move the superior capsule assembly 90 in relation to the other components.
  • the system is used as an over-the-wire device, such that the delivery catheter 50 is further configured with a lumen for a guidewire 56 (see FIG. 4). It is contemplated, however, that the system can also be used with a well known fixed wire delivery configuration.
  • the delivery catheter 50 includes a release wire 57 (see FIG. 3).
  • the release wire 57 comprises a portion of a releasing system of the delivery catheter 50 .
  • the release wire 57 is adapted to be disposed within one of the plurality of inner shaft 61 lumens and cooperates with structure attached to the graft 55 to maintain the attachment systems of the graft 55 in a collapsed configuration (see FIG. 12) as well as to facilitate the timely expansion of the attachment systems so that the graft 55 may be implanted in a lumen.
  • the release wire 57 has a diameter of approximately 0.010 inches and a length on the order of 100 cm, so that its inferior end 77 may be manipulated by the operator yet be long enough to extend beyond the repair site.
  • the inferior end 77 of the release wire 57 is attached to a rotating knob (not shown) so that when the knob is rotated, the release wire 57 wraps around the knob thereby causing it to move proximally relative to the other components of the deliver catheter 50 . It is also contemplated that, in the alternative, the inferior end 77 of the control wire 57 is adapted to be gripped by the operator.
  • the release wire 57 may be made from FEP coated nitinol.
  • the delivery catheter includes an anti-elongation wire 59 (see FIG. 2).
  • the anti-elongation wire 59 cooperates with the inner shaft 61 to prevent stretching of the inner shaft 61 during deployment of the graft 55 within the lumen.
  • a superior end 79 of the anti-elongation wire 59 is attached to the inner shaft 61 .
  • An inferior portion 78 is similarly attached to the inner shaft 61 .
  • the anti-elongation wire 59 may be disposed within a lumen of the inner shaft 61 or may be positioned along side the inner shaft 61 .
  • the diameter of the anti-elongation wire 59 is approximately 0.008 inches.
  • the anti-elongation wire 59 is made from kevlar yarn but it can also be made of stainless steel.
  • the inner shaft 61 is preferably configured with multiple lumens; however, the inner shaft 61 may be configured with a single or a plurality of lumens.
  • a guidewire lumen 63 extends the length of the inner shaft 61 .
  • a release wire lumen 64 also extends the length of the inner shaft 61 .
  • a control wire lumen 65 is provided for a control wire 91 included in the control wire assembly 54 and also extends the length of the inner shaft 61 .
  • the inner shaft 61 also includes an anti-elongation lumen 66 extending its length (see FIG. 11). Additionally, as will be hereinafter discussed in more detail, the inner shaft 61 may include a plurality of reinforcing bands, low profile projections or bumps and slits.
  • the flexible elongate element of the inner shaft 61 is preferably formed of a material suitable for intraluminal use, such as crosslinked polyethylene tubing.
  • the multi-lumen shaft 61 is preferably extruded to an outer diameter of 0.08 inches (2.03 mm).
  • the guidewire lumen 63 has an inner diameter of 0.040 inches (1.02 mm).
  • the release wire lumen 64 and the control wire lumen 65 each have a diameter of 0.022 inches (0.56 mm) but may range from 0.015 to 0.030 inches (0.381-0.762).
  • the outside diameter may range from 0.035 to 0.1 inches (0.889-2.54 mm).
  • the anti-elongation lumen 66 may have a diameter of at least 0.008 inches.
  • the inner shaft 61 may vary in length to suit the application, for example, from 50-150 cm.
  • a conical-shaped knob 100 is affixed to inner shaft 61 .
  • the conical-shaped knob 100 cooperates with the graft 55 and superior capsule assembly 90 to facilitate emplacement of the graft 55 within a lumen.
  • the inner shaft 61 also includes two release wire notches 102 , 104 which provide a space for the release wire 57 to exit and reenter the release wire lumen 64 . By providing such a space, the release wire 57 can exit the inner shaft 61 and be placed into engagement with the structure attached to the graft 55 which function to control whether the attachment systems of the graft are in their collapsed or expanded configuration.
  • each notch 102 , 104 is flanked by reinforcing bands (not shown) which add structural reinforcement to the inner shaft 61 to prevent elongation of the notches 102 , 104 as well as low profile bumps (not shown) formed on the inner shaft 61 which aid in keeping the reinforcing bands in place.
  • the material of the reinforcing bands is selected so that they perform as radiopaque markers.
  • additional bumps may be formed on the inner shaft 61 to cooperate with the superior capsule assembly 90 to limit its proximal and distal movement.
  • the delivery catheter also includes the control wire assembly 54 , which is shown in FIGS. 1 and 6.
  • the distal end of the control wire assembly 54 consists of the superior capsule assembly 90 .
  • the superior capsule assembly 90 may comprise a control wire 91 secured within a superior cap insert 96 that is placed within a superior cap 92 .
  • the superior cap 92 includes a threaded male portion that is received in a nose cone 94 having a threaded female portion.
  • the nose cone 94 is flexible and has an elongated conical or tapered shape adapted to facilitate advancement of the delivery catheter 50 through a patient's vasculature.
  • a hollow superior capsule 93 is secured to the superior cap 92 and coaxially surrounds the control wire.
  • the conical-shaped knob 100 is secured to the inner shaft 61 and may be positioned within superior capsule 93 at a location adjacent and proximal to the superior cap 92 .
  • the superior end of the control wire 95 , the superior cap insert 96 , the superior cap 92 , the nose cone 94 and the superior capsule 93 each move as a single assembly (see also FIG. 14).
  • the nose cone 94 may be made from PEBAX and the superior cap 92 may be formed from polycarbonate or other suitable material for insertion through the body lumen.
  • the nose cone 94 is formed with a bore 104 of approximately the same diameter as the outer diameter of the inner shaft 61 .
  • the superior cap insert 96 may be formed of the same material as the superior cap 92 , wherein the superior cap insert 96 is provided with a bore 105 for receiving the inner shaft 61 .
  • the superior cap 92 is further provided with a recess 106 or other means for receiving the superior end of the superior capsule 93 .
  • the superior capsule 93 is preferably formed of stainless steel, but may be formed of other suitable biocompatible material, such as a nickel titanium.
  • the superior cap recess 106 is angled to allow crimping of the superior capsule 93 to the superior cap 92 .
  • the outside diameter of the superior capsule 93 may range from 4-9 mm and is preferably 0.289 inches (7.3 mm) in outer diameter and 0.276 inches (7.01 mm) inner diameter.
  • the length of the superior capsule 93 is approximately 0.87 inches (22 mm).
  • FIGS. 13 - 15 show a presently preferred embodiment of the superior capsule assembly 90 .
  • the control wire 91 is threaded through an opening 107 in the superior cap insert 96 .
  • a longitudinal slot 109 is cut out in the inner shaft 61 to expose the control wire lumen 65 .
  • the control wire is formed in a U-shaped bend over the opening in the superior cap insert and is configured to slide within the slot and in the inner shaft lumen 65 .
  • the distal end of the control wire 95 resides in the superior cap insert 96 .
  • This configuration allows the superior cap assembly to move axially along the inner catheter shaft.
  • the U-shaped bend of the control wire through the superior cap insert prevents the superior cap assembly from rotating in relation to the inner catheter shaft. As described above, the superior cap insert is firmly secured within the superior cap.
  • control wire may be configured to pass through the superior capsule assembly, by way of the inner shaft lumen 65 , and be attached at a superior end of the superior cap. Irrespective of the embodiment, however, it is contemplated that the control wire causes relative movement of the superior capsule assembly and the inner shaft.
  • a handle assembly 110 is secured to the proximal end of the control wire 91 .
  • the handle assembly comprises a proximal body 111 , a distal body 112 , a control knob 113 with rotating shaft 114 and a hypotube 115 .
  • the two handle body parts have a central bore 119 for receiving the inner shaft 61 .
  • a retaining pin 129 may be used to secure the two pieces of the handle body together.
  • the handle assembly 110 include one or more release wire knobs (not shown), each having a rotating shaft adapted to be attached to a release wire. Upon rotation of a release wire knob, it is contemplated that the release wire wraps around the rotating shaft to thereby cause the release wire to retract.
  • the hypotube 115 is coaxially disposed over the inner shaft 61 and extends distally from the central bore 119 in the distal handle body 112 .
  • the proximal end of the hypotube is secured to the inner shaft 61 approximately one centimeter proximal from the distal end of the distal handle body by means of a polyethylene sealing tube 116 which is heat shrunk over the proximal end of the hypotube.
  • An adhesive may be used to fix the distal handle body to the hypotube.
  • Hypotube 115 consists of a rigid thin wall tube formed of a suitable material such as stainless steel.
  • the hypotube has a length of about 55 centimeters and has an outside diameter of 0.095 inches (2.41 mm) and an inside diameter of 0.087 inches (2.21 mm).
  • the hypotube may have marker bands (not shown) at predetermined positions distal of the control handle body 112 . The marker bands facilitate the correct positioning of the inferior end of the graft.
  • control wire 91 resides in an inner shaft lumen 65 and extends from the superior capsule assembly 90 to an aperture 117 located in the lumen just proximal of the proximal end of the hypotube 115 .
  • the control wire preferably consists of an elongate solid flexible stainless steel wire having a lubricating coating, such as fluorinated ethylene-propylene (FEP).
  • FEP fluorinated ethylene-propylene
  • the coated control wire is about 0.02 inches (0.508 mm) in diameter, providing sufficient strength to move the inferior capsule assembly without buckling or kinking.
  • the proximal end of the control wire 91 is disposed within a retaining rack 120 , approximately six centimeters long and having a central bore to secure the control wire.
  • the proximal end of the retaining rack 120 is slidably disposed within a longitudinal guiding slot 121 in the proximal handle 111 .
  • the distal end of the retaining rack 120 is slidably disposed within an longitudinal slot 122 in the distal handle body 112 .
  • the retaining rack 120 is configured with teeth 123 along a longitudinal edge which engage a pinion or gear 124 .
  • the pinion is attached to a lower end of the rotating shaft 114 .
  • the upper end of the rotating shaft is secured within the control knob 113 such that rotation of the control knob rotates the gear and in turn moves the retaining rack longitudinally within the guiding slots.
  • Longitudinal movement of the retaining rack causes longitudinal movement of the proximal end of the control wire 91 , causing like longitudinal movement of the distal end 95 of the control wire and of the superior capsule 93 .
  • a locking screw 118 is configured to fix the retaining rack in place. The locking screw ensures that the control wire and superior capsule will not move even if torque is applied to the control knob.
  • a locking gear 125 which has curved teeth.
  • the curved teeth engage a locking pin 126 biased by a locking spring 127 disposed within a recess 128 in the upper surface of the proximal body 111 of the control handle 110 .
  • the configuration of the curved teeth allows the control knob to turn in only one direction while the locking pin engages the locking gear. When the locking pin is moved to compress the locking spring, then the control knob may be turned in either direction.
  • the locking gear is preferably molded as part of a plastic control knob, but may be a separate mechanism secured to the base of the control knob.
  • the inferior capsule catheter 52 consists of an inferior capsule assembly 130 secured to the distal end of a flexible elongate outer shaft 131 formed of a suitable plastic material such as polyether block amide available under the trademark “PEBAX”, available from Atochem Polymers, Glen Rock, N.J.
  • the outer shaft member 131 is of a suitable length as, for example, 40 to 100 centimeters and preferably approximately 85 centimeters for the thoracic aortic artery.
  • the outer shaft has a preferred outside diameter of 0.187 inches (4.75 mm) and an inside diameter of 0.125 inches (3.175 mm).
  • the outer shaft can be produced in a certain color such as blue.
  • outer shaft may contain a radiopaque material, such as twenty percent by weight of bismuth subcarbonate or barium sulfate.
  • the outer shaft may have markings or bands distal of the wye adapter 145 at predetermined positions to indicate capsule jacket retraction and locking points.
  • the inferior capsule assembly 130 has an inferior capsule 132 mounted on the distal extremity of the outer shaft member 131 .
  • the inferior capsule has a preferred diameter ranging from 4 to 9 millimeters, which may be configured to accommodate different size grafts.
  • the length of the inferior capsule 132 is approximately 0.709 inches (18 mm).
  • the inferior capsule is configured to match the size of the superior capsule assembly 90 .
  • the inferior capsule is preferably made of stainless steel or similar impermeable and rigid, or semi-flexible material.
  • the outer shaft member also serves as a shaft for advancing the inferior capsule, as hereinafter described. Thus, the outer shaft member should have a diameter which is less than that of the inferior capsule.
  • the inferior capsule 132 is secured to the distal extremity of the outer shaft member 131 by means of a capsule adapter assembly 133 .
  • the capsule adapter assembly comprises a housing 134 and an inner sleeve 135 , which may be constructed from polycarbonate.
  • the capsule adapter housing distal extremity 136 is secured in the proximal extremity of the capsule, for example, by crimping, by using a press fit swaging or an adhesive such as a cyanoacrylate ester.
  • the capsule adapter housing distal extremity may be angled to facilitate securing the housing to the inferior capsule.
  • the proximal extremity of the capsule adapter housing 134 is secured to the distal extremity of the outer shaft member 131 by means of an cyanoacrylate ester adhesive, or other suitable means.
  • the outer shaft distal extremity is molded to form a flange 137 , wherein the capsule adapter housing is configured so as to close around the flange.
  • the capsule adapter housing is further provided with a recess for receiving the capsule adapter inner sleeve 135 .
  • the inner sleeve is provided with a bore of a suitable diameter so as to allow the inner shaft 61 to reside therein.
  • a wye adapter 145 (see FIG. 7) is secured to the proximal extremity of the outer shaft member 131 of the inferior capsule catheter 52 .
  • the central arm 146 of the wye adapter is connected to a Touhy Borst adapter 147 which tightens around the guiding member 115 disposed in the central arm of the wye adapter.
  • the side arm 148 of the wye adapter has a stop cock 149 mounted therein which is movable between open and closed positions.
  • the stop cock is provided with a Luer fitting 150 which is configured to accept a syringe for injecting a radiopaque contrast. Air may be purged from the capsule jacket assembly 53 by injecting fluid through the Luer fitting.
  • the injection fluid will exit purge ports 151 and 152 , thereby filling the capsule jacket assembly with injection fluid.
  • the Luer fitting may be attached to a saline drip line during the operative procedure.
  • the capsule jacket assembly 53 is slidably disposed coaxially over the inferior capsule catheter 52 and the inner catheter assembly 51 .
  • the capsule jacket assembly is comprised of a main jacket 160 , and a locking connector 162 .
  • the main jacket diameter changes at a point approximately 15 centimeters from the distal end 163 , depending on the length of the graft 55 .
  • the main jacket flares to an expanded diameter to cover the graft 55 , the inferior capsule 132 and the superior capsule 93 .
  • the proximal ends of the jacket may be secured to the jacket adapter 164 of the locking connector by mechanical means and by adhesive.
  • the distal end 163 of the capsule jacket extends to cover at least a portion of the superior capsule assembly 90 .
  • the capsule jacket locking connector 162 is thereby positioned proximal to the inferior capsule catheter purge port 151 .
  • locking ring 165 Prior to insertion into the lumen, locking ring 165 (not shown) is turned to hold the capsule jacket assembly firmly in place, thereby maintaining a smooth transition surface along the length of the delivery catheter 50 which resides in the body vessels.
  • the capsule jacket assembly may be moved to a furthermost proximal position, wherein at least a portion of the inferior capsule assembly 130 is exposed.
  • the locking connector is positioned just distal to the capsule catheter wye adapter 145 .
  • the locking ring may be tightened at any intermediate position to firmly secure the capsule jacket assembly at the desired location.
  • a radiopaque marker 166 is provided at the distal end of the main jacket to facilitate proper linear positioning of the capsule jacket.
  • the present invention includes an expandable intraluminal vascular graft 55 for implanting in a body vessel.
  • the graft consists of a deformable tubular member 170 which is provided with superior end 171 , inferior end 172 and a cylindrical or continuous wall extending between the superior and inferior ends 171 , 172 of the graft 55 .
  • a midsection of the tubular member of the graft 55 is crimped to resist kinking. Although a standard size crimp may be used, it is preferred to make the crimps radially deeper and less numerous than produced from standard crimping techniques.
  • Having a sparsely crimped profile also reduces the elongation properties of the graft 55 .
  • a sparsely crimped graft 55 is easier to pack into the capsule jacket than a standard crimped graft.
  • the low bulk and low elongation of the crimped graft further allows that the graft 55 may be packed into a smaller diameter capsule jacket. Additionally, the low crimp elongation factor allows for a higher degree of placement accuracy.
  • the crimps of the thoracic graft 55 may have a configuration approximating a square wave wherein the raised portion has an approximate width of 1.5 millimeters and the valley has an approximate width of 0.7 millimeters.
  • the resulting crimp pitch is then preferably 2.2 millimeters.
  • the crimped graft 55 of the present invention is configured with crimps having raised portions that are preferably approximately 1.2 millimeters deep. So configured, the graft 55 will maintain its high flexibility even under arterial pressures of over one hundred mm Hg within the corporeal lumen and the crimps will function to resist kinking. Also, by being so configured, radiopaque markers may be sewn within the selected valleys.
  • the tubular member may have a length in the range of 7 to 15 centimeters.
  • the tubular member may have a diameter of 30 to 40 mm.
  • the continuous wall can be woven of any surgical implantable material such as polyethylene terephthalate (PET or polyester), but can be made of other materials such as PTFE. It is contemplated that the wall thickness be approximately 0.005 to 0.009 inches (0.127 to 0.229 mm), thinner than most conventional woven grafts. In order to prevent unraveling of the woven material at the ends, the ends can be melted with heat to provide a small melted bead of material on each end.
  • PET polyethylene terephthalate
  • a segment of polyester yarn 199 or similar material is used to produce a thrombogenic surface to improve blood clotting along the inferior and superior ends of the main tubular member 170 .
  • the filaments of the yarn segment are teased apart to increase the embolization area.
  • the yarn segment is sutured to the wall 173 of the graft between one or more of the vees 177 of the superior and inferior attachment systems 175 , 176 .
  • Other modifications may be made as to the location of the fuzzy yarns to produce a similar result.
  • the graft may be made of velour or terry to similarly occlude blood flow around the outside of the ends of the graft adjacent the attachment system and to enhance adhesion of the graft to the aorta.
  • an expandable attachment system 175 is secured adjacent the superior end 171 of the tubular member 170 .
  • an expandable attachment system 176 is secured adjacent the tubular member's inferior end 172 .
  • Each attachment system serves to yieldably urge the tubular member from a first compressed or collapsed position to a second expanded position and provides a fluid tight seal between the graft 55 and the corporeal lumen wall.
  • Each attachment system is formed of a plurality of vees 177 with the outer apices 178 and inner apices 179 of the vees being formed with helical torsion springs 180 to yieldably urge the long legs and short legs of each of the vees outwardly at a direction approximately at right angles to the plane in which each of the vees lie.
  • the superior and inferior attachment systems 175 , 176 are comprised of a single piece of wire which is formed to provide the vees 177 and also to define the helical torsion springs 180 between the legs 181 and 182 .
  • the two ends of the single piece of wire can be welded together in one of the legs to provide a continuous spring-like attachment system and is approximately 30 mm long.
  • the attachment systems have apices lying in four longitudinally spaced-apart parallel planes which are spaced with respect to the longitudinal axis of the tubular member 170 .
  • the apices lying in each plane are staggered to provide for the minimum profile when the attachment systems are placed in its collapsed condition.
  • the superior and inferior attachment systems 175 and 176 are secured to the superior and inferior ends 171 and 172 , respectively, of the tubular member 170 by suitable means such as a polyester suture material 190 .
  • suitable means such as a polyester suture material 190 .
  • the center section of the graft be supported by one or more self-expanding attachment systems stacked end to end. (See FIG. 25).
  • the suture material is used for sewing the attachment systems onto the wall 173 of the tubular member.
  • the suture material runs along each of the legs or struts 181 and 182 and through apices 178 and 179 to firmly secure each leg to the graft and to keep outer edge of the graft 55 from sliding medially along the attachment system.
  • the inferior attachment system 176 may be attached to the inferior end 172 of the graft 55 in a similar manner.
  • the furthest extending apices protrude approximately 9 mm beyond the ends of the graft and it is contemplated that the portion of the attachment system affixed to the graft extend approximately 25 mm from the ends of the graft toward its center.
  • the attachment systems 175 , 176 may be attached to the graft 55 so that the bottom of the inner apices 179 are positioned adjacent the ends 171 , 172 of the graft 55 . By so positioning the attachment systems 175 , 176 , the fluid tight seal between the graft 55 and vessel wall may be enhanced.
  • wall engaging members 195 are preferably secured to near the center of the legs 181 , 182 by suitable means such as welding.
  • the wall engaging members are secured near the center of the legs 181 , 182 because the least amount of stress exists at the center of the legs 181 , 182 . Consequently, the fatigue life of the weld or other securing means is optimized.
  • the wall engaging members are configured to extend beyond the apices 178 , 179 approximately 2 mm and have a diameter ranging from 0.015 to 0.025 inches and a length from 2 to 5 millimeters.
  • the wall engaging members are preferably sharpened to provide conical tips, and should have a length which is sufficient for the tip to penetrate into and perhaps through the corporeal lumen wall.
  • the hook portion of the wall engaging members instead of being straight, be curved radially outward to facilitate insertion into the wall of the lumen being repaired (See FIG. 26).
  • the wall engaging members may be affixed to a strut so that the hook portion is substantially perpendicular to the plane in which the apex resides (FIGS. 23 & 24) or the hook may be routed over the apex, having its end curved radially outward so as to keep a low radial profile (FIGS. 27 & 28).
  • the superior and inferior attachment systems 175 , 176 and the wall engaging members 195 secured thereto are formed of a corrosion resistant material which has good spring and fatigue characteristics.
  • a corrosion resistant material which has good spring and fatigue characteristics.
  • One such material found to be particularly satisfactory is “ELGILOY” which is a cobalt-chromium-nickel alloy manufactured and sold by Elgiloy of Elgin, Ill.
  • the wire can have a diameter ranging from 0.016 to 0.020 inches.
  • 0.020 inch diameter wire for the frame and wall engaging members may be used in the larger grafts of 36 to 40 millimeters diameter.
  • the spring force created by the helical torsion springs 180 at the apices 178 and 179 is largely determined by the diameter of the wire.
  • the greater the diameter of the wire the greater the spring force applied to the legs 181 and 182 of the vees.
  • the longer the distances are between the apices the smaller the spring force that is applied to the legs. It therefore has been desirable to provide a spacing between the outer extremities of the legs of approximately thirty millimeters, although smaller or larger distances may be utilized.
  • the wall engaging members 195 of the superior attachment system 175 and inferior attachment system 176 may be angled with respect to the longitudinal axis of the tubular member 170 .
  • the wall engaging members face outwardly from the tubular member to facilitate holding the graft in place (See FIGS. 21 - 24 ).
  • the wall engaging members on the superior attachment means are inclined from the longitudinal axis and toward the inferior end of the graft 172 by 60° to 80° from radial.
  • the wall engaging members of the inferior attachment system may be inclined towards the superior end of the graft 175 by 60° to 80° from radial.
  • the helical torsion springs 180 placed at the apices 178 and 179 serve to facilitate compression of the graft 55 to place the superior and inferior attachment systems 175 and 176 within the capsule assemblies 90 and 130 , as hereinafter described.
  • the compression of the graft may be accomplished by deformation of the helical torsion springs to just beyond their elastic limit, thereby having a small component within the plastic range.
  • Placing the apices in different planes and staggering or offsetting the wall engaging members 195 and 196 significantly reduces the minimum compressed size of the attachment systems. Having the apices in different planes also helps to prevent the wall engaging members from becoming entangled with each other or with the apices.
  • the natural spring forces of the helical torsion springs serves to expand the graft to its expanded position as soon as the attachment system is released.
  • the spring forces of the attachment system of the graft 55 are such that the graft is securely attached within the lumen without the aid of a balloon catheter.
  • the graft 55 includes releasable ties 205 , 207 attached to its exterior near the superior and inferior ends 171 , 172 of the graft 55 respectively.
  • the releasable ties 205 , 207 cooperate with the release wire 57 of the delivery catheter 50 to load the attachment systems 175 , 176 of the graft 55 within the inferior and superior capsules assemblies 90 , 130 and to subsequently emplace the graft 55 within a corporeal lumen. As shown in FIG.
  • each releasable tie 205 , 207 consists of a single thread that is attached at its midsection to the graft 55 so that a majority of the ties 205 , 207 reside exterior to the graft 55 and configured into two loops. The loops are wrapped around the graft 55 and are placed into engagement with the release wire 57 by threading the release wire through each of the loops respectively. In the alternative, the ties 205 , 207 can be looped around the release wire 57 . Thereafter, the ends of the ties 205 , 207 are pulled tight to collapse the attachment systems 175 , 176 and are then stitched to the graft 55 and knotted.
  • the ties 205 , 207 can be threaded through the portions of the sutures which reside on the exterior of the graft and which secure the attachment systems to the graft 55 .
  • the release wire 57 is removed from engagement with the ties 205 , 207 , they are conveniently restrained from interfering with the expansion of the attachment systems.
  • the loops formed in the ties 205 , 207 upon expansion of the attachment systems, they are removed from contacting the attachment systems.
  • the ties 205 , 207 may be made from braided polyester or nylon suture or any other material having similar properties.
  • the release wire 57 is configured to pass through the walls of the graft 55 .
  • the graft 55 is contemplated to be woven, it comprises warp and weft yarns which are separated to allow passage of the release wire 57 through the walls of the graft 55 .
  • a superior passageway 209 is provided by separating warp and weft yarns located near the superior end 171 of the graft 55 .
  • an inferior passageway 211 is provided by separating warp and weft yarns located near the inferior end 172 of the graft 55 .
  • each of the passageways 209 , 211 consist of two sets of closely spaced-apart warp and weft yarns which are individually separated to allow passage of the release wire 57 through the walls of the graft 55 , wherein one of the two sets of warp and weft yarns serves as an exit and the other as an entrance.
  • each of the passageways 209 , 211 consist of one set of warp and weft yarns that is separated to thereby provide both an exit and entrance for the release wire 57 through the graft walls.
  • the releasable ties 205 , 207 maybe passed through the graft 55 in order to be placed into engagement with the release wire 57 . Further, the releasable ties 205 , 207 may be configured so that eyes which are adapted to receive the release wire are knotted into each end of the ties.
  • the release wire 57 may be passed through only one loop of each releasable tie and the other loop of each releasable tie is placed around the first loop of the releasable tie receiving the release wire in order to provide a cooperating system for compressing the attachment systems 175 , 176 .
  • the graft 55 preferably contains radiopaque markers means for locating the graft 55 and for detecting any twisting of the graft 55 during deployment.
  • the radiopaque marker means takes the form radiopaque markers 197 affixed along the crimped midsection of the graft and within the valleys comprising the crimped portion.
  • the radiopaque markers are made of a suitable material such as a platinum tungsten alloy wire of a suitable diameter such as 0.004 inches (0.102 mm) which is wound into a spring coil having a diameter of 0.4 inches (1.0 mm).
  • the radiopaque markers are secured to the tubular member 170 by sutures 199 , using the same material to secure the attachment systems to the graft.
  • the radiopaque markers 197 have a length of approximately 3 millimeters. By placing markers along the tubular member, it is possible to ascertain the position of the graft 55 and to determine whether the graft 55 has twisted between its superior and inferior ends 171 , 172 . Under fluoroscopy, the markers will be exhibited as a relatively straight lines for an untwisted graft, wherein a twisted graft will be revealed by a non-parallel pattern of markers. By placing the markers at equal increments apart, it is possible to use fluoroscopy to ascertain longitudinal compression or tension on the graft.
  • the sizing of the graft 55 may be performed on a patient-by-patient basis, or a series of sizes may be manufactured to adapt to most patient needs.
  • the length of the graft 55 is selected so to span approximately one centimeter superior and one centimeter inferior of the aneurysm, wherein the wall engaging members 195 and 196 of the graft can seat within normal tissue of the vessel on both sides of the aneurysm.
  • the graft should be about two centimeters longer than the aneurysm being repaired.
  • a conventional pigtail angiography catheter is used to determine the locations of proximal arteries to ensure they will not be covered by the implanted graft.
  • the diameter of the tubular member 170 is selected by measuring the corporeal lumen which will receive the graft by conventional radiographic techniques and then selecting a tubular member having a diameter one millimeter larger than that measured.
  • one or more pleats 198 may be sewn into the walls of the grafts so as to provide a more suitable emplacement within a lumen having a narrow portion (See FIGS. 29 - 32 ).
  • the suture material 190 used for affixing the attachment systems to the graft may be used for providing the graft with pleats.
  • FIG. 12 depicts the distal end of the delivery catheter 50 assembled for deployment.
  • the graft 55 is disposed within the capsule jacket assembly 53 .
  • the superior attachment system 175 is removably retained within the superior capsule 93 .
  • inferior attachment system 176 is removably retained within the proximal capsule 132 .
  • the superior cap 92 , nose cone 94 and superior capsule 93 are in the retracted or proximal position adjacent to the conical-shaped knob 100 .
  • control wire 91 is locked (not shown) via control knob 113 in its retracted or proximal position.
  • the outer shaft member 131 is in its most distal position in relation to inner catheter assembly 51 and is locked in place by the locking ring on the Touhy Borst adapter 147 (not shown).
  • the conical-shaped knob 100 is positioned just proximal to the superior cap 92 and is disposed within the superior capsule 93 .
  • the releasable ties 205 , 207 are wrapped around the graft 55 and are placed into engagement with the release wire 57 to thereby place the inferior and superior attachment systems 176 , 175 in a collapsed configuration.
  • the release wire 57 is configured so that it is disposed within the release wire lumen 64 of the inner shaft 61 .
  • the release wire 57 first exits the inner shaft 61 through the inferior release wire notch 102 and then passes through the inferior passageway 211 of the graft 55 and through the loops of the inferior releasable tie 207 (see FIGS. 33 and 34). From there, the release wire 57 passes back through the inferior passageway 211 and inferior release wire notch 102 of the inner shaft 61 and back into the release wire lumen 64 .
  • the release wire 57 then passes through the release wire lumen 64 until it reaches the second release wire notch 104 formed in the inner shaft 61 .
  • the release wire 57 passes through the second notch 104 and through the superior passageway 209 of the graft 55 and through the loops formed in the superior releasable tie 205 . Finally, the release wire 57 reenters the inner shaft 61 by again passing through the superior passageway 209 and the second release wire notch 104 and advances distally within the release wire lumen 64 . By so configuring the release wire 57 , the attachment systems 175 , 176 are locked to the inner shaft 61 both radially and axially.
  • each release wire is configured to cooperate with one of the releasable ties 205 , 207 .
  • the first release wire 57 may be configured to cooperate with the releasable tie 207 attached to the inferior end 172 of the graft and the second release wire 217 may be configured to cooperate with the releasable tie 205 attached to the superior end 171 of the graft 55 .
  • the first release wire 57 is configured to pass through the inferior notch 102 and the second release wire 217 is configured to pass through the superior or second notch 104 .
  • the two release wires may share the release wire lumen 64 or a second release wire lumen may be formed in the inner shaft 69 .
  • FIG. 12 shows the attachment of the anti-elongation wire 59 to the inner shaft 61 .
  • the anti-elongation wire 59 is advanced through the anti-elongation wire lumen 66 until it reaches a longitudinal position along the inner shaft 61 near where the graft 55 is loaded in a delivery catheter 50 assembled for deployment. At this longitudinal position, the anti-elongation wire 59 exits the inner shaft 61 through an anti-elongation wire notch 213 and is affixed to the inner shaft 61 by way of an anti-elongation band 215 .
  • the anti-elongation wire 59 is inserted through a gap or hole formed in the band 215 and tied into a knot to thereby prevent proximal movement of the anti-elongation wire relative to the inner shaft 61 .
  • the anti-elongation wire 59 is similarly affixed to the inner shaft 61 at its proximal end in that it exits the inner shaft 61 , passes through another band flanked by low profile bumps (not shown) and is tied in a knot to prevent distal movement of the anti-elongation wire relative to the inner shaft 61 .
  • the anti-elongation wire 59 lies outside the inner shaft 61 but is similarly attached to the inner shaft 61 to prevent elongation thereof.
  • the capsule jacket assembly 53 is positioned such that the distal end of the capsule jacket main jacket 160 overlaps at least a portion of the distal capsule 93 .
  • capsule jacket locking connector 162 (not shown) secures the main jacket in place.
  • the following describes a method of repair of an aortic aneurysm using the method comprising the present invention for intraluminal placement of a graft in an aorta.
  • a patient is prepared in a conventional manner by use of a guide wire 56 , a dilator and sheath (not shown) to open the iliac artery or abdominal aorta or vessel of the patient.
  • the distal end of the delivery catheter 50 is then inserted into the sheath, which has previously been placed in the vessel.
  • inner shaft lumen 63 is provided for receiving the guide wire 56 .
  • the following procedure may also be used when the guiding member is constructed as part of the inner catheter assembly 51 .
  • the guide wire 56 is introduced by the physician into the femoral artery and advanced to the desired location in the aorta 200 and adjacent to the diseased or damaged portion of the vessel 201 .
  • the inner catheter assembly 51 , the inferior capsule catheter 52 , the capsule jacket assembly 53 , the control wire assembly 54 and the releasing system are all configured for deployment of the graft as shown in FIGS. 1 and 12.
  • the assemblies are advanced by the physician as a single unit over the guide wire.
  • the physician uses the handle assembly 110 and the proximal end of the inner shaft member 70 to guide the distal end of the assemblies over the guide wire.
  • the locking connector 162 of the capsule jacket assembly 53 is loosened to allow movement of the capsule jacket main jacket 160 (See FIG. 1). It is to be noted that the capsule jacket main jacket 160 may be withdrawn prior or subsequent to advancing the graft 55 and delivery catheter 50 to the repair site. While using one hand to firmly grasp the inferior capsule catheter 52 and hold it stationary, the physician grasps the jacket adapter 164 with the other hand and gently pulls the jacket adapter proximally towards the capsule catheter wye adapter 145 , as shown in FIG. 37. The capsule jacket assembly 53 is moved to fully expose graft 55 and the inferior and superior capsule assemblies 90 , 130 .
  • the releasing system retains the graft 55 within the inferior and superior capsules assemblies 90 , 130 .
  • the release wire 57 functions to limit relative movement of the ends of the graft 55 and the capsules by engaging the releasable ties 205 , 207 wrapped around the graft 55 (see FIG. 12).
  • the locking connector 162 is then tightened to hold the capsule jacket assembly 53 in place.
  • the control knob 113 is then rotated to cause relative movement between the superior capsule assembly 90 and the inner catheter assembly 51 to expose the superior attachment system 175 (see FIGS. 1, 12 & 38 ).
  • Rotating the control knob 113 causes the retaining rack 120 to move the control wire 91 in a distal direction. Since the superior cap 92 and superior capsule 93 are secured to the control wire 91 , they move in corresponding relationship with the rotation of the control knob 113 .
  • the superior capsule assembly 90 is moved from engagement with the superior attachment system 175 , the conical-shaped knob is exposed, creating a smooth profile at the proximal end of the superior capsule to thereby facilitate removal of the superior end of the delivery catheter from within the implanted graft.
  • the anti-elongation wire 59 functions to prevent the inner shaft 61 from stretching.
  • the control knob 113 is turned, the control wire 91 and superior capsule assembly 90 advance within the vasculature of the patient.
  • the force advancing the capsule assembly 90 may stretch the inner shaft 61 rather than slide the capsule assembly 90 distally on the inner shaft 61 .
  • the anti-elongation wire prevents this.
  • the inferior capsule catheter 52 is next moved proximally, which results in the inferior attachment system 176 to be removed from the inferior capsule assembly 130 (see also FIGS. 1 & 12).
  • the release wire 57 can be withdrawn from engagement with the superior and inferior ties 205 , 207 to thereby allow the attachment systems 175 , 176 to spring open and engage the walls of the lumen (see FIGS. 40, 41).
  • the ties 205 , 207 remain attached to the exterior of the graft and out of blood flow.
  • the force with which the attachment systems 175 , 176 spring open in conjunction with the forces applied by the blood present in the aorta against the interior of the graft 55 , operates to seat the attachment systems of the graft 55 within the aorta.
  • the method of deployment described involved removing each attachment system from the capsules prior to withdrawing the release wire 57 , it is to be understood that, for example, the superior attachment system 175 can be removed from the superior capsule assembly 90 and the release wire 57 withdrawn to allow the superior attachment system 175 to engage the walls of the lumen prior to doing the same with the inferior attachment system 176 so that the inferior attachment system 176 engages the lumen.
  • the wall engaging members 195 of the superior attachment system 175 point proximally and with the direction of blood flow, whereas the wall engaging members 195 of the inferior attachment system 176 point distally and against the direction of blood flow.
  • the graft 55 is prevented from migrating downstream or upstream within the aorta.
  • the wall engaging members 195 of the superior attachment system 175 prevent the graft 55 from migrating downstream in response to forces applied to the graft 55 by the direction of blood flow.
  • the wall engaging members 195 of the inferior attachment system 176 prevent the graft from migrating upstream in response to forces applied by the blood within the aorta.
  • a number of the steps of the previously described method for placing the graft 55 within a vessel lumen may be reordered so that the inferior end 172 of the graft 55 may be attached within the lumen prior to attaching the superior end 171 of the graft 55 within the lumen.
  • This alternate procedure may be preferred when repairing a thoracic aortic aneurysm because of the high blood flow and flow rate in the thoracic region of the aorta.
  • the two release wire system (see FIG. 35) may be employed.
  • the inferior attachment system 176 can be permitted to engage the walls of the lumen before the superior attachment system 175 does so, to thereby attach the inferior end 172 of the graft 55 within the lumen before the superior end 171 is attached within the lumen.
  • the second release wire 217 can then be withdrawn to attach the superior end 171 of the graft 55 within the lumen.
  • This dual release wire system can also be used to attach the superior end 172 of the graft 55 within the lumen first.
  • the delivery catheter is removed from the patient (not shown).
  • the superior capsule assembly 90 and distal end of the inner shaft 61 are moved proximal relative to the graft 55 by first loosening the locking ring 147 (See FIG. 1). Then, while holding the inferior capsule catheter 52 in place by grasping the wye adapter 145 with one hand, the inner catheter assembly 51 is moved proximally by gently pulling the handle assembly 110 with the other hand.
  • the proximal end of the superior capsule 93 may be mated with the inferior capsule for smooth transition.
  • the capsule jacket locking connector 162 is loosened. While holding the capsule jacket adapter 164 in place, the inner catheter assembly and inferior capsule catheter 51 and 52 are moved proximally and in unison by gently pulling the wye 145 of the inferior capsule catheter. The catheters are moved until the distal end of the main jacket 163 covers the superior capsule 93 or until the inferior capsule adapter housing 134 mates with the flared transition of the capsule jacket, thereby creating a smooth transition along the entire length of the delivery catheter 50 . Thereafter, the inner catheter assembly 57 , inferior capsule catheter 52 , capsule jacket assembly 53 and control wire assembly 54 are removed from the aorta through the incision. The graft 55 and attachment systems 175 and 176 remain secured to the vessel wall 202 , thereby sealing the aneurysm 201 from blood flow.
  • the entire procedure described herein can be observed under fluoroscopy.
  • the relative positioning of the graft 55 and the delivery catheter 50 can be readily ascertained by the radiopaque attachment systems 175 and 176 , radiopaque markers 197 provided on the graft, and the radiopaque marker 87 on the inner shaft 61 (See FIG. 5). If any twisting of the graft has occurred between placement of the superior attachment system and the inferior attachment system, then the twisting can be readily ascertained by observing the series of markers 197 . Adjustments to eliminate any twisting which may have occurred can be made before exposing the graft's second extremity 172 by rotation of the catheter 52 . Any excessive graft tension or compression can be ascertained by observing the radiopaque markers 197 under fluoroscopy. Adjustments to graft tension can be made before exposing the second extremity of the graft by applying tension on the capsule catheter assembly 52 .
  • Post implant fluoroscopy procedures can be utilized to confirm the proper implantation of the device by the use of a conventional angiographic pigtail catheter or by injecting radiopaque contrast into the guide wire lumen of the balloon catheter shaft. Thereafter the jacket can be removed from the patient and the incisions closed with conventional suturing techniques. Tissues should begin to grow into the graft within two to four weeks. This establishes a complete repair of the aneurysm which had occurred.

Abstract

A delivery catheter having an inner catheter assembly, an inferior capsule catheter, and a capsule jacket assembly for use in deploying a graft having a compressible and expandable attachment systems in the thoracic region of an aorta. The graft is comprised of a tubular member having superior and inferior ends, each having an attachment system with wall engaging members secured thereto and is crimped along its midsection to resist kinking and elongation. The delivery catheter includes an inferior capsule assembly for releasably retaining the inferior attachment system of the graft and a superior capsule assembly for releasably retaining the superior attachment system of the graft as well as a releasing system for maintaining the attachment systems in a compressed configuration and for facilitating expansion of the attachment systems. The delivery catheter also includes an anti-elongation wire attached to the inner catheter assembly to prevent stretching of the delivery catheter during deployment of the graft within the aorta. Upon removing the attachment systems from the capsule, the releasing system functions to allow the attachment systems to assume their expanded configuration and engage the walls of the aorta. The graft and attachment systems remain in the vessel after the delivery catheter is withdrawn.

Description

  • This application is a continuation-in-part of application Ser. No. 102,576 filed Aug. 5, 1993, which is a continuation-in-part of application Ser. No. 553,530 filed on Jul. 13, 1990, which is a continuation-in-part of application Ser. No. 166,093 filed on Mar. 9, 1988, now U.S. Pat. No. 5,104,399, which is a continuation-in-part of application Ser. No. 940,907 filed on Dec. 10, 1986, now U.S. Pat. No. 4,787,899 which is a continuation of application Ser. No. 559,935 filed on Dec. 9, 1983, now abandoned. The contents of each of these applications are hereby incorporated by reference.[0001]
  • BACKGROUND OF THE INVENTION
  • This invention relates to a system for implanting a prosthesis, and more particularly, to a delivery catheter for placing a graft having an attachment system within a corporeal lumen. [0002]
  • It is well established that various fluid conducting body or corporeal lumens, such as veins and arteries, may deteriorate or suffer trauma so that repair is necessary. For example, various types of aneurysms or other deteriorative diseases may affect the ability of the lumen to conduct fluids and, in turn, may be life-threatening. In some cases, the damaged lumen is repairable only with the use of a prosthesis such as an artificial vessel or graft. For repair of vital vessels such as the aorta, repair may be significantly life-threatening. Techniques known in the art which tend to minimize dangers to the patient include a procedure in which a graft resembling the natural vessel is placed within the diseased or obstructed section of the natural vessel. [0003]
  • More specifically, it is known within the art to provide a prosthesis for intraluminal repair of a vessel. In intraluminal vessel repair, the prosthesis is advanced intraluminally through the vessel to the repair site using a delivery catheter and deployed within the vessel so that the prosthesis traverses the diseased portion to thereby repair the vessel. [0004]
  • Generally speaking, varied concerns arise when repairing the different deteriorated disease that may affect a vessel. For instance, thoracic aneurysms differ from other aortic aneurysms in several respects. As may well be expected, due to their proximity to the heart, there are concerns specific to thoracic aneurysms that are not evident in the repair of other types of aortic aneurysms. Moreover, the size and shape of the thoracic aneurysms differ and are often more varied than other types of aortic aneurysms [0005]
  • In particular, thoracic aneurysms are often close to what are typically called the great arteries, such as the left subclavian artery, or may be found to occur proximal to the celiac trunk. These lumens, which branch away from the thoracic region of the aorta, are critical to the body's circulatory system and carry high volumes of blood to various parts of the body. Consequently, these lumens generally cannot be occluded by a prosthesis used to intraluminally repair a thoracic aneurysm unless additional procedures are performed to bypass the occluded lumen. [0006]
  • In addition, thoracic aneurysms have diameters that are typically larger and have shapes perhaps more variable than other aortic aneurysms. The average neck diameter of thoracic aneurysms is on the order of 34-36 mm and the average length approximately 10 cm with a range of 5-16 cm. To complicate matters, due to the curvature of the aortic arch, the superior neck of thoracic aneurysms are often at a different angle from that of the inferior neck. Also, among the myriad of shapes they may take on, thoracic aneurysms may be fusiform in shape, or comprise giant penetrating ulcers. [0007]
  • Further, access to thoracic aneurysms through connecting arteries is limited and methods for implanting a prosthesis must take into account the physiology of and effects to the heart. Specifically, the femoral as well as the iliac arteries may be too narrow to pass a catheter for delivering a thoracic prosthesis or graft. Often, surgical repair of a thoracic aortic aneurysm requires thoracotomy. Also, it is not desirable for catheters delivering a thoracic graft to comprise a balloon since the use of the balloon to implant the graft would temporarily stop blood flow, thereby placing potentially dangerous loads upon the heart. Finally, due to high pressures existing in the area of a thoracic aneurysm, the attachment system of a graft for repairing a thoracic aneurysm must be sufficient to prohibit migration of the graft. It is also to be noted that there is typically a lack of calcification in the area of thoracic aneurysms. Consequently, the attachment systems of grafts for repairing thoracic aneurysms generally need not be placed within the lumen with forces overcoming such hardening of tissue. [0008]
  • Thus, what has been needed and heretofore unavailable is a graft and a delivery catheter system therefor, wherein the graft is designed specifically to repair thoracic aortic aneurysms and the delivery system functions to precisely position a graft within an aorta to thereby completely repair the thoracic aneurysm. The graft is to be configured to conform to the various possibilities of shapes of the thoracic aneurysm and to have an attachment system which effectively affixes the graft within the aorta. In addition, the delivery catheter is to effectively operate within the unique anatomical constraints of the thoracic portion of the aorta. The present invention accomplishes these goals. [0009]
  • SUMMARY OF THE INVENTION
  • Briefly, and in general terms, the present invention provides a new and improved graft and delivery catheter and a novel method for their use in repairing a lumen. The graft is configured for repairing a diseased condition of the lumen. The delivery catheter is configured to introduce the graft within or between vessels or corporeal lumens of an animal, such as a human, and to facilitate the deployment of the graft at the repair sites. [0010]
  • The present graft has a diameter that is larger than that of conventional grafts so that relatively larger lumens may be repaired and its walls are thinner to facilitate packing it within the delivery catheter. The attachment system of the present graft is expandable and is stiffer and has hooks with greater angles from radial than conventional attachment systems. Also, in addition to being secured to the ends of the graft, the attachment system is secured by its apices to the graft to prevent relative motion of the attachment system and graft. Further, the novel attachment system of the present graft enables it to self expand quickly and forcefully without the aid of a balloon catheter as well as enables it to securely hold the graft within lumens carrying high volume of blood. [0011]
  • The present delivery catheter includes structure for quickly deploying the graft within the lumen to be repaired. Further, by not employing a balloon catheter, the delivery catheter may be utilized to repair lumens located near the heart without placing undue stress on the heart and is configured for packing a larger diameter graft within the delivery catheter. Additionally, the delivery catheter is configured to hold the attachment systems affixed to the ends of the graft within capsules and by not placing the entire graft within a single capsule, larger diameter grafts may be packed within the delivery catheter. Moreover, the delivery catheter is longer which enables it to reach an aortic arch and employs a novel releasing system cooperating with the capsules which, in conjunction, operate to facilitate loading as well as deployment of the graft. The releasing system includes a release wire cooperating with releasable ties attached to the exterior of the graft to maintain the attachment systems of the graft in a collapsed configuration and to facilitate the expansion of the attachment systems so that they properly and quickly engage the walls of the lumen. [0012]
  • The present invention provides a prosthesis or graft for intraluminal placement in a fluid conducting corporeal lumen. The graft is hollow and has a pre-selected cross-section, length and wall thickness. The graft is deformable to conform substantially to the interior surface of the corporeal lumen or other body part to be repaired. The midsection of the graft may be crimped to resist kinking and facilitate placement accuracy and may comprise radiopaque markers attached along its length to help orient the graft using fluoroscopy or X-ray techniques. Tufts of yarn are sewn into the graft at its ends to facilitate healing and placement of the graft within the corporeal lumen. Preferably, the graft comprises woven polyester or another material suitable for permanent placement in the body such as PTFE. The superior and inferior ends of the graft are positioned within the corporeal lumen and the graft is configured such that it traverses the diseased or damaged portion of the vessel. To anchor the graft to the wall of the corporeal lumen, attachment systems are secured to the superior and inferior ends of the graft. [0013]
  • The preferred attachment system includes wall engaging members. The wall engaging members of the superior attachment systems are angled toward the inferior end of the graft. Similarly, the wall engaging members of the inferior attachment systems are angled toward the superior end of the graft. Specifically, the angles of both the superior and inferior wall engaging members are in the range of 60-80° from radial. The wall engaging members of both attachment systems have sharp tips for engaging the corporeal lumen wall. The preferred attachment systems are formed into a staggered V-shape lattice or framework, the apices of which comprise helical torsion springs. The frame of the attachment systems allows for elastic radial deformation resulting in a spring-like effect when a compressed attachment system is allowed to expand as the graft is released from the capsules, and by having a high stiffness, they function to quickly and forcefully seat the graft within the lumen. [0014]
  • Preferably, the delivery catheter of the present inventor is flexible and includes an elongate cylindrical jacket overlaying a superior capsule assembly and an inferior capsule assembly, each of which are adapted to releasably retain an end of the graft. The superior capsule assembly further includes an elongated flexible conical-shaped or tapered nose cone adapted to facilitate the advancement of the delivery catheter through a patient's vasculature. Attached at the most proximal end of the inferior capsule assembly is an elongate outer shaft, comprising an inferior capsule catheter, which is adapted to receive a multi-lumen inner shaft. The lumens of the inner shaft are conduits for a guidewire, one or two release wires, an anti-elongation wire and a control wire that cooperates with the superior capsule assembly. Attached to the inner shaft and distal to the outer shaft/inferior capsule assembly junction is a conical-shaped knob that cooperates with the superior capsule assembly. Also attached to the inner shaft is an anti-elongation wire that functions to minimize elongation of the inner shaft during deployment of the graft. The jacket is capable of moving relative to the rest of the catheter and thus can be withdrawn, thereby exposing the capsules and graft. Similarly, the capsules can be caused to move relative to the inner shaft and the structure attached thereto, which, in conjunction with the operation of the releasing system, thereby causes the deployment of the graft within a lumen. The length of the delivery catheter is sufficient for use in reaching the thoracic portion of the aorta and has a diameter suited for encasing a graft for use in repairing a thoracic aneurysm. [0015]
  • Deployment of the graft comprises a series of steps which begins with introducing the delivery catheter into the corporeal lumen using well known surgical techniques. The delivery catheter is manipulated so that the graft retained by the superior and inferior capsule assemblies is positioned at a desired location within the corporeal lumen. Once the graft is in the desired location, the jacket is retracted and the superior and inferior capsule assemblies are removed from the graft to expose the superior and inferior attachment systems of the graft. After this is accomplished, the releasing system is employed to thereby allow the attachment systems self-expand and seat the graft within the lumen. [0016]
  • Two methods are contemplated for placing the graft within a lumen. As a first step in each method, the jacket is moved proximally to expose the graft retained by the superior and inferior capsules. In the first method, the superior capsule assembly is moved distally to expose the superior end of the graft and the inferior capsule assembly is moved proximally to expose the inferior end of the graft. The releasing system is then employed to release the superior attachment system, thereby allowing the superior attachment system to affix the superior end of the graft within the lumen. Thereafter, the releasing system is employed to release the inferior attachment system to thereby allow the inferior attachment system to affix the inferior end of the graft within the lumen. In the second method, these steps are reordered so that the inferior end of the graft is first seated within the lumen and thereafter, the superior end is seated.[0017]
  • Other features and advantages of the present invention will become apparent from the following detailed description, taken in conjunction with the accompanied drawings, which illustrate, by way of example, the features of the invention. [0018]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a top plan view of the delivery catheter and graft incorporating the present invention. [0019]
  • FIG. 2 is a top plan view of a an anti-elongation wire of the present invention. [0020]
  • FIG. 3 is a top plan view of a release wire of the present invention. [0021]
  • FIG. 4 is a top plan view of a guidewire to be used with the delivery catheter of the present invention. [0022]
  • FIG. 5 is a top plan view of an inner catheter assembly of the present invention. [0023]
  • FIG. 6 is a top plan view of a superior capsule assembly, control wire, hypotube and control wire handle assembly of the present invention. [0024]
  • FIG. 7 is a top plan view of an inferior capsule and capsule catheter of the present invention. [0025]
  • FIG. 8 is a top plan view of a capsule jacket assembly of the present invention. [0026]
  • FIG. 9 is a top plan view of a graft for use with the delivery catheter of the present invention. [0027]
  • FIG. 10 is a cross-sectional view taken along the line [0028] 10-10 of FIG. 1.
  • FIG. 11 is an alternate embodiment of the view depicted in FIG. 10. [0029]
  • FIG. 12 is a partial cross-sectional view of the inferior capsule, superior capsule and capsule jacket assemblies and the anti-elongation wire, release wire and graft. [0030]
  • FIG. 13 is an enlarged perspective view showing a presently preferred embodiment of the distal end of the control wire, superior cap insert, superior cap and nose cone. [0031]
  • FIG. 14 is an enlarged cross-sectional view of the superior capsule assembly. [0032]
  • FIG. 15 is a cross-sectional view taken along the line [0033] 15-15 of FIG. 14.
  • FIG. 16 is a partial cross-sectional view of the control wire and control handle mechanism of FIG. 1. [0034]
  • FIG. 17 is a cross-sectional view taken along the line [0035] 17-17 of FIG. 16.
  • FIG. 18 is a cross-sectional view taken along the line [0036] 18-18 of FIG. 16.
  • FIG. 19 is a cross-sectional view taken along the line [0037] 19-19 of FIG. 16.
  • FIG. 20 is a cross-sectional view taken along the line [0038] 20-20 of FIG. 16.
  • FIG. 21 is a partial cross-sectional view of the graft and attachment system of the present invention. [0039]
  • FIG. 22 is a cross-sectional view taken along the line [0040] 22-22 of FIG. 21.
  • FIG. 23 is an enlarged perspective view showing a superior attachment system. [0041]
  • FIG. 24 is an enlarged perspective view showing an inferior attachment system. [0042]
  • FIG. 25 is a perspective view showing an alternate embodiment of the graft. [0043]
  • FIG. 26 is an enlarged perspective view showing an alternate embodiment of the wall engaging members of the attachment system. [0044]
  • FIG. 27 is an enlarged perspective view showing an alternate embodiment of the wall engaging member of the present invention. [0045]
  • FIG. 28 is an enlarged perspective view showing another view of the alternate embodiment of FIG. 27. [0046]
  • FIG. 29 is a perspective view showing another embodiment of the graft. [0047]
  • FIG. 30 is a cross-sectional view of the graft depicted in FIG. 29. [0048]
  • FIG. 31 is a perspective view showing yet another embodiment of the graft. [0049]
  • FIG. 32 is a cross-sectional view of the graft depicted in FIG. 31. [0050]
  • FIG. 33 is a partial cross-sectional view of the delivery catheter and graft, illustrating a releasing system of the delivery catheter. [0051]
  • FIG. 34 is a cross-sectional view taken along the line of [0052] 34-34 of FIG. 33.
  • FIG. 35 is a partial cross-sectioned view of the delivery catheter and graft, illustrating another embodiment of the releasing system of the delivery catheter. [0053]
  • FIG. 36 is a partial cross-sectional view of the delivery catheter and graft positioned within the corporeal lumen. [0054]
  • FIG. 37 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 33, wherein the capsule jacket has been retracted proximally relative to the delivery catheter. [0055]
  • FIG. 38 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 34, wherein the superior capsule assembly has been removed from the superior end of the graft. [0056]
  • FIG. 39 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 35, wherein the inferior capsule has been removed from the inferior end of the graft. [0057]
  • FIG. 40 is partial cross-sectional view of the delivery catheter and graft shown in FIG. 36, wherein the release system has been used to facilitate emplacement of the superior attachment system within the corporeal lumen. [0058]
  • FIG. 41 is a partial cross-sectional view of the delivery catheter and graft shown in FIG. 37, wherein the release system has been utilized to facilitate emplacement of the inferior attachment system within the corporeal lumen.[0059]
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • As is shown in the drawings and for purposes of illustration, the invention is embodied in a thoracic graft and a delivery catheter therefor. One of the novel features of the present invention is the attachment system of the graft which operates to securely affix the graft within a lumen without the aid of a balloon catheter. Another novel feature of the present invention is the releasing system which functions to release the attachment systems of the graft once the graft has been advanced within the vasculature of the patient to the repair site. [0060]
  • Generally, in the present invention, the graft is comprised of a monoluminal tubular member having superior and inferior extremities. Expandable attachment systems are secured to the superior and inferior ends of the tubular member. The attachment systems are provided with wall engaging members which are covered by the inferior and superior capsule assemblies. The delivery catheter includes a plurality of elongate components which are configured coaxially so that relative movement between them provides for deployment of the graft. [0061]
  • In more detail, the [0062] delivery catheter 50 is shown in FIGS. 1-8. As shown in FIG. 1, the delivery catheter 50 includes an inner catheter assembly 51, which is coaxially disposed within an inferior capsule catheter 52, which is coaxially disposed within the capsule jacket 53. Also disposed about the inner catheter is a superior capsule assembly 90. Attached to the inferior capsule catheter 52 is an inferior capsule assembly 130. The inferior capsule assembly 130 and the superior capsule assembly 90 are used to contain the attachment systems of the graft 55. A control wire assembly 54 (see FIG. 6) is coaxially disposed within one of a plurality of lumens of an inner shaft 61 included in the inner catheter assembly 51 and is configured to move the superior capsule assembly 90 in relation to the other components. In the preferred embodiment, the system is used as an over-the-wire device, such that the delivery catheter 50 is further configured with a lumen for a guidewire 56 (see FIG. 4). It is contemplated, however, that the system can also be used with a well known fixed wire delivery configuration.
  • Moreover, the [0063] delivery catheter 50 includes a release wire 57 (see FIG. 3). The release wire 57 comprises a portion of a releasing system of the delivery catheter 50. The release wire 57 is adapted to be disposed within one of the plurality of inner shaft 61 lumens and cooperates with structure attached to the graft 55 to maintain the attachment systems of the graft 55 in a collapsed configuration (see FIG. 12) as well as to facilitate the timely expansion of the attachment systems so that the graft 55 may be implanted in a lumen. Preferably, the release wire 57 has a diameter of approximately 0.010 inches and a length on the order of 100 cm, so that its inferior end 77 may be manipulated by the operator yet be long enough to extend beyond the repair site. In a presently preferred embodiment, the inferior end 77 of the release wire 57 is attached to a rotating knob (not shown) so that when the knob is rotated, the release wire 57 wraps around the knob thereby causing it to move proximally relative to the other components of the deliver catheter 50. It is also contemplated that, in the alternative, the inferior end 77 of the control wire 57 is adapted to be gripped by the operator. The release wire 57 may be made from FEP coated nitinol.
  • Additionally, the delivery catheter includes an anti-elongation wire [0064] 59 (see FIG. 2). The anti-elongation wire 59 cooperates with the inner shaft 61 to prevent stretching of the inner shaft 61 during deployment of the graft 55 within the lumen. A superior end 79 of the anti-elongation wire 59 is attached to the inner shaft 61. An inferior portion 78 is similarly attached to the inner shaft 61. The anti-elongation wire 59 may be disposed within a lumen of the inner shaft 61 or may be positioned along side the inner shaft 61. Preferably, the diameter of the anti-elongation wire 59 is approximately 0.008 inches. In one presently preferred embodiment, the anti-elongation wire 59 is made from kevlar yarn but it can also be made of stainless steel.
  • As shown in FIG. 10, the [0065] inner shaft 61 is preferably configured with multiple lumens; however, the inner shaft 61 may be configured with a single or a plurality of lumens. A guidewire lumen 63 extends the length of the inner shaft 61. A release wire lumen 64 also extends the length of the inner shaft 61. A control wire lumen 65 is provided for a control wire 91 included in the control wire assembly 54 and also extends the length of the inner shaft 61. In an alternative embodiment, the inner shaft 61 also includes an anti-elongation lumen 66 extending its length (see FIG. 11). Additionally, as will be hereinafter discussed in more detail, the inner shaft 61 may include a plurality of reinforcing bands, low profile projections or bumps and slits.
  • The flexible elongate element of the [0066] inner shaft 61 is preferably formed of a material suitable for intraluminal use, such as crosslinked polyethylene tubing. The multi-lumen shaft 61 is preferably extruded to an outer diameter of 0.08 inches (2.03 mm). The guidewire lumen 63 has an inner diameter of 0.040 inches (1.02 mm). The release wire lumen 64 and the control wire lumen 65 each have a diameter of 0.022 inches (0.56 mm) but may range from 0.015 to 0.030 inches (0.381-0.762). The outside diameter may range from 0.035 to 0.1 inches (0.889-2.54 mm). In the embodiment of the inner shaft 61 that includes the anti-elongation lumen 66, the anti-elongation lumen 66 may have a diameter of at least 0.008 inches. The inner shaft 61 may vary in length to suit the application, for example, from 50-150 cm.
  • As shown in FIGS. 5 and 12, a conical-shaped [0067] knob 100 is affixed to inner shaft 61. As will be developed below, the conical-shaped knob 100 cooperates with the graft 55 and superior capsule assembly 90 to facilitate emplacement of the graft 55 within a lumen. The inner shaft 61 also includes two release wire notches 102, 104 which provide a space for the release wire 57 to exit and reenter the release wire lumen 64. By providing such a space, the release wire 57 can exit the inner shaft 61 and be placed into engagement with the structure attached to the graft 55 which function to control whether the attachment systems of the graft are in their collapsed or expanded configuration. In one presently preferred embodiment, each notch 102, 104 is flanked by reinforcing bands (not shown) which add structural reinforcement to the inner shaft 61 to prevent elongation of the notches 102, 104 as well as low profile bumps (not shown) formed on the inner shaft 61 which aid in keeping the reinforcing bands in place. Preferably, the material of the reinforcing bands is selected so that they perform as radiopaque markers. Further, additional bumps (not shown) may be formed on the inner shaft 61 to cooperate with the superior capsule assembly 90 to limit its proximal and distal movement.
  • The delivery catheter also includes the control wire assembly [0068] 54, which is shown in FIGS. 1 and 6. The distal end of the control wire assembly 54 consists of the superior capsule assembly 90. As shown in more detail in FIGS. 13-15, the superior capsule assembly 90 may comprise a control wire 91 secured within a superior cap insert 96 that is placed within a superior cap 92. The superior cap 92 includes a threaded male portion that is received in a nose cone 94 having a threaded female portion. The nose cone 94 is flexible and has an elongated conical or tapered shape adapted to facilitate advancement of the delivery catheter 50 through a patient's vasculature. A hollow superior capsule 93 is secured to the superior cap 92 and coaxially surrounds the control wire.
  • As shown in FIG. 12, the conical-shaped [0069] knob 100 is secured to the inner shaft 61 and may be positioned within superior capsule 93 at a location adjacent and proximal to the superior cap 92. As the control wire is moved in a longitudinal manner, the superior end of the control wire 95, the superior cap insert 96, the superior cap 92, the nose cone 94 and the superior capsule 93 each move as a single assembly (see also FIG. 14).
  • The [0070] nose cone 94 may be made from PEBAX and the superior cap 92 may be formed from polycarbonate or other suitable material for insertion through the body lumen. The nose cone 94 is formed with a bore 104 of approximately the same diameter as the outer diameter of the inner shaft 61. Similarly, the superior cap insert 96 may be formed of the same material as the superior cap 92, wherein the superior cap insert 96 is provided with a bore 105 for receiving the inner shaft 61. The superior cap 92 is further provided with a recess 106 or other means for receiving the superior end of the superior capsule 93. The superior capsule 93 is preferably formed of stainless steel, but may be formed of other suitable biocompatible material, such as a nickel titanium. The superior cap recess 106 is angled to allow crimping of the superior capsule 93 to the superior cap 92.
  • The outside diameter of the [0071] superior capsule 93 may range from 4-9 mm and is preferably 0.289 inches (7.3 mm) in outer diameter and 0.276 inches (7.01 mm) inner diameter. The length of the superior capsule 93 is approximately 0.87 inches (22 mm).
  • FIGS. [0072] 13-15 show a presently preferred embodiment of the superior capsule assembly 90. In this embodiment, the control wire 91 is threaded through an opening 107 in the superior cap insert 96. A longitudinal slot 109 is cut out in the inner shaft 61 to expose the control wire lumen 65. The control wire is formed in a U-shaped bend over the opening in the superior cap insert and is configured to slide within the slot and in the inner shaft lumen 65. The distal end of the control wire 95 resides in the superior cap insert 96. This configuration allows the superior cap assembly to move axially along the inner catheter shaft. The U-shaped bend of the control wire through the superior cap insert, however, prevents the superior cap assembly from rotating in relation to the inner catheter shaft. As described above, the superior cap insert is firmly secured within the superior cap.
  • It is to be understood that other embodiments of the superior capsule assembly are contemplated. For instance, the control wire may be configured to pass through the superior capsule assembly, by way of the [0073] inner shaft lumen 65, and be attached at a superior end of the superior cap. Irrespective of the embodiment, however, it is contemplated that the control wire causes relative movement of the superior capsule assembly and the inner shaft.
  • As shown in FIGS. [0074] 16-20, a handle assembly 110 is secured to the proximal end of the control wire 91. The handle assembly comprises a proximal body 111, a distal body 112, a control knob 113 with rotating shaft 114 and a hypotube 115. The two handle body parts have a central bore 119 for receiving the inner shaft 61. A retaining pin 129 may be used to secure the two pieces of the handle body together. It is also contemplated that the handle assembly 110 include one or more release wire knobs (not shown), each having a rotating shaft adapted to be attached to a release wire. Upon rotation of a release wire knob, it is contemplated that the release wire wraps around the rotating shaft to thereby cause the release wire to retract.
  • The [0075] hypotube 115 is coaxially disposed over the inner shaft 61 and extends distally from the central bore 119 in the distal handle body 112. The proximal end of the hypotube is secured to the inner shaft 61 approximately one centimeter proximal from the distal end of the distal handle body by means of a polyethylene sealing tube 116 which is heat shrunk over the proximal end of the hypotube. An adhesive may be used to fix the distal handle body to the hypotube.
  • [0076] Hypotube 115 consists of a rigid thin wall tube formed of a suitable material such as stainless steel. The hypotube has a length of about 55 centimeters and has an outside diameter of 0.095 inches (2.41 mm) and an inside diameter of 0.087 inches (2.21 mm). When a crimped graft 55 is used, the hypotube may have marker bands (not shown) at predetermined positions distal of the control handle body 112. The marker bands facilitate the correct positioning of the inferior end of the graft.
  • Referring to FIG. 16, the [0077] control wire 91 resides in an inner shaft lumen 65 and extends from the superior capsule assembly 90 to an aperture 117 located in the lumen just proximal of the proximal end of the hypotube 115. The control wire preferably consists of an elongate solid flexible stainless steel wire having a lubricating coating, such as fluorinated ethylene-propylene (FEP). The coated control wire is about 0.02 inches (0.508 mm) in diameter, providing sufficient strength to move the inferior capsule assembly without buckling or kinking.
  • The proximal end of the [0078] control wire 91 is disposed within a retaining rack 120, approximately six centimeters long and having a central bore to secure the control wire. The proximal end of the retaining rack 120 is slidably disposed within a longitudinal guiding slot 121 in the proximal handle 111. Similarly, the distal end of the retaining rack 120 is slidably disposed within an longitudinal slot 122 in the distal handle body 112.
  • The [0079] retaining rack 120 is configured with teeth 123 along a longitudinal edge which engage a pinion or gear 124. The pinion is attached to a lower end of the rotating shaft 114. The upper end of the rotating shaft is secured within the control knob 113 such that rotation of the control knob rotates the gear and in turn moves the retaining rack longitudinally within the guiding slots. Longitudinal movement of the retaining rack causes longitudinal movement of the proximal end of the control wire 91, causing like longitudinal movement of the distal end 95 of the control wire and of the superior capsule 93. As shown in FIGS. 17 and 19, a locking screw 118 is configured to fix the retaining rack in place. The locking screw ensures that the control wire and superior capsule will not move even if torque is applied to the control knob.
  • At the base of the [0080] control knob 113 is a locking gear 125 which has curved teeth. The curved teeth engage a locking pin 126 biased by a locking spring 127 disposed within a recess 128 in the upper surface of the proximal body 111 of the control handle 110. The configuration of the curved teeth allows the control knob to turn in only one direction while the locking pin engages the locking gear. When the locking pin is moved to compress the locking spring, then the control knob may be turned in either direction. The locking gear is preferably molded as part of a plastic control knob, but may be a separate mechanism secured to the base of the control knob.
  • As shown in FIGS. 1 and 7, the [0081] inferior capsule catheter 52 consists of an inferior capsule assembly 130 secured to the distal end of a flexible elongate outer shaft 131 formed of a suitable plastic material such as polyether block amide available under the trademark “PEBAX”, available from Atochem Polymers, Glen Rock, N.J. The outer shaft member 131 is of a suitable length as, for example, 40 to 100 centimeters and preferably approximately 85 centimeters for the thoracic aortic artery. The outer shaft has a preferred outside diameter of 0.187 inches (4.75 mm) and an inside diameter of 0.125 inches (3.175 mm). The outer shaft can be produced in a certain color such as blue. To render the outer shaft radiopaque under x-rays, its material of construction may contain a radiopaque material, such as twenty percent by weight of bismuth subcarbonate or barium sulfate. The outer shaft may have markings or bands distal of the wye adapter 145 at predetermined positions to indicate capsule jacket retraction and locking points.
  • The [0082] inferior capsule assembly 130 has an inferior capsule 132 mounted on the distal extremity of the outer shaft member 131. The inferior capsule has a preferred diameter ranging from 4 to 9 millimeters, which may be configured to accommodate different size grafts. The length of the inferior capsule 132 is approximately 0.709 inches (18 mm). The inferior capsule is configured to match the size of the superior capsule assembly 90. The inferior capsule is preferably made of stainless steel or similar impermeable and rigid, or semi-flexible material. The outer shaft member also serves as a shaft for advancing the inferior capsule, as hereinafter described. Thus, the outer shaft member should have a diameter which is less than that of the inferior capsule.
  • Referring to FIG. 12, the [0083] inferior capsule 132 is secured to the distal extremity of the outer shaft member 131 by means of a capsule adapter assembly 133. The capsule adapter assembly comprises a housing 134 and an inner sleeve 135, which may be constructed from polycarbonate. The capsule adapter housing distal extremity 136 is secured in the proximal extremity of the capsule, for example, by crimping, by using a press fit swaging or an adhesive such as a cyanoacrylate ester. The capsule adapter housing distal extremity may be angled to facilitate securing the housing to the inferior capsule.
  • The proximal extremity of the [0084] capsule adapter housing 134 is secured to the distal extremity of the outer shaft member 131 by means of an cyanoacrylate ester adhesive, or other suitable means. To facilitate a mechanical lock, the outer shaft distal extremity is molded to form a flange 137, wherein the capsule adapter housing is configured so as to close around the flange. The capsule adapter housing is further provided with a recess for receiving the capsule adapter inner sleeve 135. The inner sleeve is provided with a bore of a suitable diameter so as to allow the inner shaft 61 to reside therein.
  • A wye adapter [0085] 145 (see FIG. 7) is secured to the proximal extremity of the outer shaft member 131 of the inferior capsule catheter 52. The central arm 146 of the wye adapter is connected to a Touhy Borst adapter 147 which tightens around the guiding member 115 disposed in the central arm of the wye adapter. The side arm 148 of the wye adapter has a stop cock 149 mounted therein which is movable between open and closed positions. The stop cock is provided with a Luer fitting 150 which is configured to accept a syringe for injecting a radiopaque contrast. Air may be purged from the capsule jacket assembly 53 by injecting fluid through the Luer fitting. The injection fluid will exit purge ports 151 and 152, thereby filling the capsule jacket assembly with injection fluid. The Luer fitting may be attached to a saline drip line during the operative procedure.
  • Referring to FIGS. 1, 8 and [0086] 12, the capsule jacket assembly 53 is slidably disposed coaxially over the inferior capsule catheter 52 and the inner catheter assembly 51. The capsule jacket assembly is comprised of a main jacket 160, and a locking connector 162. The main jacket diameter changes at a point approximately 15 centimeters from the distal end 163, depending on the length of the graft 55. The main jacket flares to an expanded diameter to cover the graft 55, the inferior capsule 132 and the superior capsule 93. The proximal ends of the jacket may be secured to the jacket adapter 164 of the locking connector by mechanical means and by adhesive.
  • When the [0087] capsule jacket assembly 53 is in its most distal position, the distal end 163 of the capsule jacket extends to cover at least a portion of the superior capsule assembly 90. Similarly, the capsule jacket locking connector 162 is thereby positioned proximal to the inferior capsule catheter purge port 151. Prior to insertion into the lumen, locking ring 165 (not shown) is turned to hold the capsule jacket assembly firmly in place, thereby maintaining a smooth transition surface along the length of the delivery catheter 50 which resides in the body vessels. When the locking ring is released, the capsule jacket assembly may be moved to a furthermost proximal position, wherein at least a portion of the inferior capsule assembly 130 is exposed. Thus, the locking connector is positioned just distal to the capsule catheter wye adapter 145. The locking ring may be tightened at any intermediate position to firmly secure the capsule jacket assembly at the desired location. In addition, a radiopaque marker 166 is provided at the distal end of the main jacket to facilitate proper linear positioning of the capsule jacket.
  • As shown in FIGS. 1 and 9, the present invention includes an expandable intraluminal [0088] vascular graft 55 for implanting in a body vessel. Referring to FIG. 21, the graft consists of a deformable tubular member 170 which is provided with superior end 171, inferior end 172 and a cylindrical or continuous wall extending between the superior and inferior ends 171, 172 of the graft 55. A midsection of the tubular member of the graft 55 is crimped to resist kinking. Although a standard size crimp may be used, it is preferred to make the crimps radially deeper and less numerous than produced from standard crimping techniques. Having a sparsely crimped profile also reduces the elongation properties of the graft 55. Moreover, a sparsely crimped graft 55 is easier to pack into the capsule jacket than a standard crimped graft. The low bulk and low elongation of the crimped graft further allows that the graft 55 may be packed into a smaller diameter capsule jacket. Additionally, the low crimp elongation factor allows for a higher degree of placement accuracy.
  • The crimps of the [0089] thoracic graft 55 may have a configuration approximating a square wave wherein the raised portion has an approximate width of 1.5 millimeters and the valley has an approximate width of 0.7 millimeters. The resulting crimp pitch is then preferably 2.2 millimeters. Further, the crimped graft 55 of the present invention is configured with crimps having raised portions that are preferably approximately 1.2 millimeters deep. So configured, the graft 55 will maintain its high flexibility even under arterial pressures of over one hundred mm Hg within the corporeal lumen and the crimps will function to resist kinking. Also, by being so configured, radiopaque markers may be sewn within the selected valleys.
  • The tubular member may have a length in the range of 7 to 15 centimeters. The tubular member may have a diameter of 30 to 40 mm. The continuous wall can be woven of any surgical implantable material such as polyethylene terephthalate (PET or polyester), but can be made of other materials such as PTFE. It is contemplated that the wall thickness be approximately 0.005 to 0.009 inches (0.127 to 0.229 mm), thinner than most conventional woven grafts. In order to prevent unraveling of the woven material at the ends, the ends can be melted with heat to provide a small melted bead of material on each end. [0090]
  • As shown in FIG. 21, a segment of [0091] polyester yarn 199 or similar material is used to produce a thrombogenic surface to improve blood clotting along the inferior and superior ends of the main tubular member 170. The filaments of the yarn segment are teased apart to increase the embolization area. The yarn segment is sutured to the wall 173 of the graft between one or more of the vees 177 of the superior and inferior attachment systems 175, 176. Other modifications may be made as to the location of the fuzzy yarns to produce a similar result. Likewise, the graft may be made of velour or terry to similarly occlude blood flow around the outside of the ends of the graft adjacent the attachment system and to enhance adhesion of the graft to the aorta.
  • Referring to FIG. 21, an [0092] expandable attachment system 175 is secured adjacent the superior end 171 of the tubular member 170. Similarly, an expandable attachment system 176 is secured adjacent the tubular member's inferior end 172. Each attachment system serves to yieldably urge the tubular member from a first compressed or collapsed position to a second expanded position and provides a fluid tight seal between the graft 55 and the corporeal lumen wall. Each attachment system is formed of a plurality of vees 177 with the outer apices 178 and inner apices 179 of the vees being formed with helical torsion springs 180 to yieldably urge the long legs and short legs of each of the vees outwardly at a direction approximately at right angles to the plane in which each of the vees lie.
  • As shown in more detail in FIGS. 23 and 24, the superior and [0093] inferior attachment systems 175, 176 are comprised of a single piece of wire which is formed to provide the vees 177 and also to define the helical torsion springs 180 between the legs 181 and 182. The two ends of the single piece of wire can be welded together in one of the legs to provide a continuous spring-like attachment system and is approximately 30 mm long. In the construction shown in FIGS. 23 and 24, it can be seen that the attachment systems have apices lying in four longitudinally spaced-apart parallel planes which are spaced with respect to the longitudinal axis of the tubular member 170. The apices lying in each plane are staggered to provide for the minimum profile when the attachment systems are placed in its collapsed condition.
  • The superior and [0094] inferior attachment systems 175 and 176 are secured to the superior and inferior ends 171 and 172, respectively, of the tubular member 170 by suitable means such as a polyester suture material 190. In an alternate embodiment, however, it is further contemplated that the center section of the graft be supported by one or more self-expanding attachment systems stacked end to end. (See FIG. 25). As shown in FIG. 21, the suture material is used for sewing the attachment systems onto the wall 173 of the tubular member. The suture material runs along each of the legs or struts 181 and 182 and through apices 178 and 179 to firmly secure each leg to the graft and to keep outer edge of the graft 55 from sliding medially along the attachment system. The inferior attachment system 176 may be attached to the inferior end 172 of the graft 55 in a similar manner. The furthest extending apices protrude approximately 9 mm beyond the ends of the graft and it is contemplated that the portion of the attachment system affixed to the graft extend approximately 25 mm from the ends of the graft toward its center. In a presently preferred embodiment, the attachment systems 175,176 may be attached to the graft 55 so that the bottom of the inner apices 179 are positioned adjacent the ends 171,172 of the graft 55. By so positioning the attachment systems 175,176, the fluid tight seal between the graft 55 and vessel wall may be enhanced.
  • As shown in FIGS. [0095] 22-24, wall engaging members 195 are preferably secured to near the center of the legs 181, 182 by suitable means such as welding. The wall engaging members are secured near the center of the legs 181, 182 because the least amount of stress exists at the center of the legs 181, 182. Consequently, the fatigue life of the weld or other securing means is optimized. The wall engaging members are configured to extend beyond the apices 178,179 approximately 2 mm and have a diameter ranging from 0.015 to 0.025 inches and a length from 2 to 5 millimeters. The wall engaging members are preferably sharpened to provide conical tips, and should have a length which is sufficient for the tip to penetrate into and perhaps through the corporeal lumen wall. There may be eight wall engaging members 195 per attachment system, one extending beyond each inner and outer apex 178, 179, or there may be four wall engaging members 195 per attachment system, wherein a wall engaging member extends beyond each outer apex 178. It is also contemplated that the hook portion of the wall engaging members, instead of being straight, be curved radially outward to facilitate insertion into the wall of the lumen being repaired (See FIG. 26). Further, the wall engaging members may be affixed to a strut so that the hook portion is substantially perpendicular to the plane in which the apex resides (FIGS. 23 & 24) or the hook may be routed over the apex, having its end curved radially outward so as to keep a low radial profile (FIGS. 27 & 28).
  • The superior and [0096] inferior attachment systems 175, 176 and the wall engaging members 195 secured thereto are formed of a corrosion resistant material which has good spring and fatigue characteristics. One such material found to be particularly satisfactory is “ELGILOY” which is a cobalt-chromium-nickel alloy manufactured and sold by Elgiloy of Elgin, Ill. The wire can have a diameter ranging from 0.016 to 0.020 inches. For example, 0.020 inch diameter wire for the frame and wall engaging members may be used in the larger grafts of 36 to 40 millimeters diameter.
  • It has been found that the spring force created by the helical torsion springs [0097] 180 at the apices 178 and 179 is largely determined by the diameter of the wire. The greater the diameter of the wire, the greater the spring force applied to the legs 181 and 182 of the vees. Also, the longer the distances are between the apices, the smaller the spring force that is applied to the legs. It therefore has been desirable to provide a spacing between the outer extremities of the legs of approximately thirty millimeters, although smaller or larger distances may be utilized.
  • To facilitate securing the [0098] graft 55 in the corporeal lumen, the wall engaging members 195 of the superior attachment system 175 and inferior attachment system 176 may be angled with respect to the longitudinal axis of the tubular member 170. The wall engaging members face outwardly from the tubular member to facilitate holding the graft in place (See FIGS. 21-24). Preferably, the wall engaging members on the superior attachment means are inclined from the longitudinal axis and toward the inferior end of the graft 172 by 60° to 80° from radial. Likewise, the wall engaging members of the inferior attachment system may be inclined towards the superior end of the graft 175 by 60° to 80° from radial. By angling the wall engaging members so that they resist the force of the blood flow, the implanted wall engaging members oppose migration of the graft.
  • The helical torsion springs [0099] 180 placed at the apices 178 and 179 serve to facilitate compression of the graft 55 to place the superior and inferior attachment systems 175 and 176 within the capsule assemblies 90 and 130, as hereinafter described. The compression of the graft may be accomplished by deformation of the helical torsion springs to just beyond their elastic limit, thereby having a small component within the plastic range. Placing the apices in different planes and staggering or offsetting the wall engaging members 195 and 196 significantly reduces the minimum compressed size of the attachment systems. Having the apices in different planes also helps to prevent the wall engaging members from becoming entangled with each other or with the apices. The natural spring forces of the helical torsion springs serves to expand the graft to its expanded position as soon as the attachment system is released. Significantly, the spring forces of the attachment system of the graft 55 are such that the graft is securely attached within the lumen without the aid of a balloon catheter.
  • The [0100] graft 55 includes releasable ties 205, 207 attached to its exterior near the superior and inferior ends 171, 172 of the graft 55 respectively. The releasable ties 205, 207 cooperate with the release wire 57 of the delivery catheter 50 to load the attachment systems 175, 176 of the graft 55 within the inferior and superior capsules assemblies 90, 130 and to subsequently emplace the graft 55 within a corporeal lumen. As shown in FIG. 22, each releasable tie 205, 207 consists of a single thread that is attached at its midsection to the graft 55 so that a majority of the ties 205, 207 reside exterior to the graft 55 and configured into two loops. The loops are wrapped around the graft 55 and are placed into engagement with the release wire 57 by threading the release wire through each of the loops respectively. In the alternative, the ties 205, 207 can be looped around the release wire 57. Thereafter, the ends of the ties 205, 207 are pulled tight to collapse the attachment systems 175, 176 and are then stitched to the graft 55 and knotted.
  • It is to be noted that the [0101] ties 205, 207 can be threaded through the portions of the sutures which reside on the exterior of the graft and which secure the attachment systems to the graft 55. By doing so, when the release wire 57 is removed from engagement with the ties 205, 207, they are conveniently restrained from interfering with the expansion of the attachment systems. Further, due to the relative small size of the loops formed in the ties 205, 207, upon expansion of the attachment systems, they are removed from contacting the attachment systems. Moreover, by so configuring the ties 205, 207, they are kept out of the way of blood flow and are, therefore, made unavailable for occluding the vessel or causing the formation of unwanted blood clots. The ties 205, 207 may be made from braided polyester or nylon suture or any other material having similar properties.
  • In order to engage the [0102] releasable ties 205, 207, the release wire 57 is configured to pass through the walls of the graft 55. Since the graft 55 is contemplated to be woven, it comprises warp and weft yarns which are separated to allow passage of the release wire 57 through the walls of the graft 55. A superior passageway 209 is provided by separating warp and weft yarns located near the superior end 171 of the graft 55. Similarly, an inferior passageway 211 is provided by separating warp and weft yarns located near the inferior end 172 of the graft 55. In a presently preferred embodiment, each of the passageways 209, 211 consist of two sets of closely spaced-apart warp and weft yarns which are individually separated to allow passage of the release wire 57 through the walls of the graft 55, wherein one of the two sets of warp and weft yarns serves as an exit and the other as an entrance. In an alternate embodiment, each of the passageways 209, 211 consist of one set of warp and weft yarns that is separated to thereby provide both an exit and entrance for the release wire 57 through the graft walls.
  • In other embodiments, the [0103] releasable ties 205, 207 maybe passed through the graft 55 in order to be placed into engagement with the release wire 57. Further, the releasable ties 205, 207 may be configured so that eyes which are adapted to receive the release wire are knotted into each end of the ties. Additionally, it is also contemplated that, rather than passing the release wire 57 through each loop of each releasable tie 205, 207, the release wire 57 may be passed through only one loop of each releasable tie and the other loop of each releasable tie is placed around the first loop of the releasable tie receiving the release wire in order to provide a cooperating system for compressing the attachment systems 175, 176.
  • The [0104] graft 55 preferably contains radiopaque markers means for locating the graft 55 and for detecting any twisting of the graft 55 during deployment. The radiopaque marker means takes the form radiopaque markers 197 affixed along the crimped midsection of the graft and within the valleys comprising the crimped portion. The radiopaque markers are made of a suitable material such as a platinum tungsten alloy wire of a suitable diameter such as 0.004 inches (0.102 mm) which is wound into a spring coil having a diameter of 0.4 inches (1.0 mm). The radiopaque markers are secured to the tubular member 170 by sutures 199, using the same material to secure the attachment systems to the graft.
  • Referring also to FIG. 21, the [0105] radiopaque markers 197 have a length of approximately 3 millimeters. By placing markers along the tubular member, it is possible to ascertain the position of the graft 55 and to determine whether the graft 55 has twisted between its superior and inferior ends 171, 172. Under fluoroscopy, the markers will be exhibited as a relatively straight lines for an untwisted graft, wherein a twisted graft will be revealed by a non-parallel pattern of markers. By placing the markers at equal increments apart, it is possible to use fluoroscopy to ascertain longitudinal compression or tension on the graft.
  • The sizing of the [0106] graft 55 may be performed on a patient-by-patient basis, or a series of sizes may be manufactured to adapt to most patient needs. For the repair of a thoracic aneurysm, the length of the graft 55 is selected so to span approximately one centimeter superior and one centimeter inferior of the aneurysm, wherein the wall engaging members 195 and 196 of the graft can seat within normal tissue of the vessel on both sides of the aneurysm. Thus, the graft should be about two centimeters longer than the aneurysm being repaired. During the pre-implant fluoroscopy procedure, a conventional pigtail angiography catheter is used to determine the locations of proximal arteries to ensure they will not be covered by the implanted graft. Similarly, the diameter of the tubular member 170 is selected by measuring the corporeal lumen which will receive the graft by conventional radiographic techniques and then selecting a tubular member having a diameter one millimeter larger than that measured. For specific applications, one or more pleats 198 may be sewn into the walls of the grafts so as to provide a more suitable emplacement within a lumen having a narrow portion (See FIGS. 29-32). The suture material 190 used for affixing the attachment systems to the graft may be used for providing the graft with pleats.
  • FIG. 12 depicts the distal end of the [0107] delivery catheter 50 assembled for deployment. The graft 55 is disposed within the capsule jacket assembly 53. The superior attachment system 175 is removably retained within the superior capsule 93. Likewise, inferior attachment system 176 is removably retained within the proximal capsule 132. The superior cap 92, nose cone 94 and superior capsule 93 are in the retracted or proximal position adjacent to the conical-shaped knob 100. Similarly, control wire 91 is locked (not shown) via control knob 113 in its retracted or proximal position. During initial deployment, the outer shaft member 131 is in its most distal position in relation to inner catheter assembly 51 and is locked in place by the locking ring on the Touhy Borst adapter 147 (not shown).
  • During initial deployment, the conical-shaped [0108] knob 100 is positioned just proximal to the superior cap 92 and is disposed within the superior capsule 93. Moreover, as depicted in FIG. 12, the releasable ties 205, 207 are wrapped around the graft 55 and are placed into engagement with the release wire 57 to thereby place the inferior and superior attachment systems 176, 175 in a collapsed configuration.
  • Further, the [0109] release wire 57 is configured so that it is disposed within the release wire lumen 64 of the inner shaft 61. The release wire 57 first exits the inner shaft 61 through the inferior release wire notch 102 and then passes through the inferior passageway 211 of the graft 55 and through the loops of the inferior releasable tie 207 (see FIGS. 33 and 34). From there, the release wire 57 passes back through the inferior passageway 211 and inferior release wire notch 102 of the inner shaft 61 and back into the release wire lumen 64. The release wire 57 then passes through the release wire lumen 64 until it reaches the second release wire notch 104 formed in the inner shaft 61. The release wire 57 passes through the second notch 104 and through the superior passageway 209 of the graft 55 and through the loops formed in the superior releasable tie 205. Finally, the release wire 57 reenters the inner shaft 61 by again passing through the superior passageway 209 and the second release wire notch 104 and advances distally within the release wire lumen 64. By so configuring the release wire 57, the attachment systems 175, 176 are locked to the inner shaft 61 both radially and axially.
  • In another embodiment of the [0110] delivery catheter 50, it is contemplated to include a second release wire 217 (see FIG. 35). In this embodiment, each release wire is configured to cooperate with one of the releasable ties 205, 207. For instance, the first release wire 57 may be configured to cooperate with the releasable tie 207 attached to the inferior end 172 of the graft and the second release wire 217 may be configured to cooperate with the releasable tie 205 attached to the superior end 171 of the graft 55. Also, in the two release wire system, the first release wire 57 is configured to pass through the inferior notch 102 and the second release wire 217 is configured to pass through the superior or second notch 104. Further, the two release wires may share the release wire lumen 64 or a second release wire lumen may be formed in the inner shaft 69.
  • Referring again to FIG. 12, it shows the attachment of the [0111] anti-elongation wire 59 to the inner shaft 61. In one presently preferred embodiment, the anti-elongation wire 59 is advanced through the anti-elongation wire lumen 66 until it reaches a longitudinal position along the inner shaft 61 near where the graft 55 is loaded in a delivery catheter 50 assembled for deployment. At this longitudinal position, the anti-elongation wire 59 exits the inner shaft 61 through an anti-elongation wire notch 213 and is affixed to the inner shaft 61 by way of an anti-elongation band 215. Formed into the exterior of the inner shaft 61 and positioned on either side of the band 215 may be low profile bumps (not shown) which facilitate retaining the band 215 in place on the inner shaft 61. The anti-elongation wire 59 is inserted through a gap or hole formed in the band 215 and tied into a knot to thereby prevent proximal movement of the anti-elongation wire relative to the inner shaft 61. The anti-elongation wire 59 is similarly affixed to the inner shaft 61 at its proximal end in that it exits the inner shaft 61, passes through another band flanked by low profile bumps (not shown) and is tied in a knot to prevent distal movement of the anti-elongation wire relative to the inner shaft 61. In another presently preferred embodiment, the anti-elongation wire 59 lies outside the inner shaft 61 but is similarly attached to the inner shaft 61 to prevent elongation thereof.
  • Further, as shown in FIG. 12, the [0112] capsule jacket assembly 53 is positioned such that the distal end of the capsule jacket main jacket 160 overlaps at least a portion of the distal capsule 93. During deployment, capsule jacket locking connector 162 (not shown) secures the main jacket in place. Thus, when any movement or force is applied to the handle assembly 110, the entire apparatus 50 moves as a single unit.
  • By way of example, the following describes a method of repair of an aortic aneurysm using the method comprising the present invention for intraluminal placement of a graft in an aorta. First, a patient is prepared in a conventional manner by use of a [0113] guide wire 56, a dilator and sheath (not shown) to open the iliac artery or abdominal aorta or vessel of the patient. The distal end of the delivery catheter 50 is then inserted into the sheath, which has previously been placed in the vessel. In the preferred embodiment of the present invention, inner shaft lumen 63 is provided for receiving the guide wire 56. However, the following procedure may also be used when the guiding member is constructed as part of the inner catheter assembly 51.
  • As shown in FIG. 36, the [0114] guide wire 56 is introduced by the physician into the femoral artery and advanced to the desired location in the aorta 200 and adjacent to the diseased or damaged portion of the vessel 201. The inner catheter assembly 51, the inferior capsule catheter 52, the capsule jacket assembly 53, the control wire assembly 54 and the releasing system are all configured for deployment of the graft as shown in FIGS. 1 and 12. Thus, the assemblies are advanced by the physician as a single unit over the guide wire. The physician uses the handle assembly 110 and the proximal end of the inner shaft member 70 to guide the distal end of the assemblies over the guide wire.
  • Next, the locking [0115] connector 162 of the capsule jacket assembly 53 is loosened to allow movement of the capsule jacket main jacket 160 (See FIG. 1). It is to be noted that the capsule jacket main jacket 160 may be withdrawn prior or subsequent to advancing the graft 55 and delivery catheter 50 to the repair site. While using one hand to firmly grasp the inferior capsule catheter 52 and hold it stationary, the physician grasps the jacket adapter 164 with the other hand and gently pulls the jacket adapter proximally towards the capsule catheter wye adapter 145, as shown in FIG. 37. The capsule jacket assembly 53 is moved to fully expose graft 55 and the inferior and superior capsule assemblies 90, 130. At this time, the releasing system retains the graft 55 within the inferior and superior capsules assemblies 90, 130. The release wire 57 functions to limit relative movement of the ends of the graft 55 and the capsules by engaging the releasable ties 205, 207 wrapped around the graft 55 (see FIG. 12). The locking connector 162 is then tightened to hold the capsule jacket assembly 53 in place.
  • The [0116] control knob 113 is then rotated to cause relative movement between the superior capsule assembly 90 and the inner catheter assembly 51 to expose the superior attachment system 175 (see FIGS. 1, 12 & 38). Rotating the control knob 113 causes the retaining rack 120 to move the control wire 91 in a distal direction. Since the superior cap 92 and superior capsule 93 are secured to the control wire 91, they move in corresponding relationship with the rotation of the control knob 113. As the superior capsule assembly 90 is moved from engagement with the superior attachment system 175, the conical-shaped knob is exposed, creating a smooth profile at the proximal end of the superior capsule to thereby facilitate removal of the superior end of the delivery catheter from within the implanted graft. At this point, the anti-elongation wire 59 functions to prevent the inner shaft 61 from stretching. As the control knob 113 is turned, the control wire 91 and superior capsule assembly 90 advance within the vasculature of the patient. However, if the inner shaft 61 is easily stretched and if the distal end of the catheter is bent relative to the superior capsule assembly 90, the force advancing the capsule assembly 90 may stretch the inner shaft 61 rather than slide the capsule assembly 90 distally on the inner shaft 61. The anti-elongation wire prevents this.
  • As shown in FIG. 39, with the [0117] handle assembly 110 held firmly in place, the inferior capsule catheter 52 is next moved proximally, which results in the inferior attachment system 176 to be removed from the inferior capsule assembly 130 (see also FIGS. 1 & 12). Once the inferior attachment system 176 is free of the inferior capsule assembly 130, the release wire 57 can be withdrawn from engagement with the superior and inferior ties 205, 207 to thereby allow the attachment systems 175, 176 to spring open and engage the walls of the lumen (see FIGS. 40, 41). The ties 205, 207 remain attached to the exterior of the graft and out of blood flow. The force with which the attachment systems 175, 176 spring open, in conjunction with the forces applied by the blood present in the aorta against the interior of the graft 55, operates to seat the attachment systems of the graft 55 within the aorta.
  • Although the method of deployment described involved removing each attachment system from the capsules prior to withdrawing the [0118] release wire 57, it is to be understood that, for example, the superior attachment system 175 can be removed from the superior capsule assembly 90 and the release wire 57 withdrawn to allow the superior attachment system 175 to engage the walls of the lumen prior to doing the same with the inferior attachment system 176 so that the inferior attachment system 176 engages the lumen. Further, it is important to avoid placing the graft 55 in excessive longitudial tension, as such a condition may cause the graft 55 to close should it be deployed in a curved position of a lumen. To avoid placing the graft 55 in such a condition, the end of the graft 55 which is yet to be deployed can be moved toward the end of the graft 55 that has been deployed.
  • When the [0119] graft 55 is seated within the aorta, the wall engaging members 195 of the superior attachment system 175 point proximally and with the direction of blood flow, whereas the wall engaging members 195 of the inferior attachment system 176 point distally and against the direction of blood flow. By so orienting the wall engaging members 195, the graft 55 is prevented from migrating downstream or upstream within the aorta. The wall engaging members 195 of the superior attachment system 175 prevent the graft 55 from migrating downstream in response to forces applied to the graft 55 by the direction of blood flow. Similarly, the wall engaging members 195 of the inferior attachment system 176 prevent the graft from migrating upstream in response to forces applied by the blood within the aorta.
  • A number of the steps of the previously described method for placing the [0120] graft 55 within a vessel lumen may be reordered so that the inferior end 172 of the graft 55 may be attached within the lumen prior to attaching the superior end 171 of the graft 55 within the lumen. This alternate procedure may be preferred when repairing a thoracic aortic aneurysm because of the high blood flow and flow rate in the thoracic region of the aorta. By attaching the inferior end of the graft first, the drag on the partially implanted graft may be minimized, thereby avoiding the potential problem of the graft 55 being forced from engagement with the vessel lumen.
  • In order to attach the [0121] inferior end 172 of the graft 55 within the lumen prior to attaching the superior end 171 within the lumen, the two release wire system (see FIG. 35) may be employed. By withdrawing the first release wire 57 prior to withdrawing the second release wire 217, the inferior attachment system 176 can be permitted to engage the walls of the lumen before the superior attachment system 175 does so, to thereby attach the inferior end 172 of the graft 55 within the lumen before the superior end 171 is attached within the lumen. The second release wire 217 can then be withdrawn to attach the superior end 171 of the graft 55 within the lumen. This dual release wire system can also be used to attach the superior end 172 of the graft 55 within the lumen first.
  • As a final step in any of the methods employed, the delivery catheter is removed from the patient (not shown). The [0122] superior capsule assembly 90 and distal end of the inner shaft 61 are moved proximal relative to the graft 55 by first loosening the locking ring 147 (See FIG. 1). Then, while holding the inferior capsule catheter 52 in place by grasping the wye adapter 145 with one hand, the inner catheter assembly 51 is moved proximally by gently pulling the handle assembly 110 with the other hand. The proximal end of the superior capsule 93 may be mated with the inferior capsule for smooth transition.
  • Finally, the capsule [0123] jacket locking connector 162 is loosened. While holding the capsule jacket adapter 164 in place, the inner catheter assembly and inferior capsule catheter 51 and 52 are moved proximally and in unison by gently pulling the wye 145 of the inferior capsule catheter. The catheters are moved until the distal end of the main jacket 163 covers the superior capsule 93 or until the inferior capsule adapter housing 134 mates with the flared transition of the capsule jacket, thereby creating a smooth transition along the entire length of the delivery catheter 50. Thereafter, the inner catheter assembly 57, inferior capsule catheter 52, capsule jacket assembly 53 and control wire assembly 54 are removed from the aorta through the incision. The graft 55 and attachment systems 175 and 176 remain secured to the vessel wall 202, thereby sealing the aneurysm 201 from blood flow.
  • The entire procedure described herein can be observed under fluoroscopy. The relative positioning of the [0124] graft 55 and the delivery catheter 50 can be readily ascertained by the radiopaque attachment systems 175 and 176, radiopaque markers 197 provided on the graft, and the radiopaque marker 87 on the inner shaft 61 (See FIG. 5). If any twisting of the graft has occurred between placement of the superior attachment system and the inferior attachment system, then the twisting can be readily ascertained by observing the series of markers 197. Adjustments to eliminate any twisting which may have occurred can be made before exposing the graft's second extremity 172 by rotation of the catheter 52. Any excessive graft tension or compression can be ascertained by observing the radiopaque markers 197 under fluoroscopy. Adjustments to graft tension can be made before exposing the second extremity of the graft by applying tension on the capsule catheter assembly 52.
  • Post implant fluoroscopy procedures can be utilized to confirm the proper implantation of the device by the use of a conventional angiographic pigtail catheter or by injecting radiopaque contrast into the guide wire lumen of the balloon catheter shaft. Thereafter the jacket can be removed from the patient and the incisions closed with conventional suturing techniques. Tissues should begin to grow into the graft within two to four weeks. This establishes a complete repair of the aneurysm which had occurred. [0125]
  • While several particular forms of the invention have been illustrated and described, it will be apparent that various modifications can be made without departing from the spirit and scope of the invention. For example, references to materials of construction and specific dimensions are also not intended to be limiting in any manner and other materials and dimensions could be substituted and remain within the spirit and scope of the invention. Accordingly, it is not intended that the invention be limited, except as by the appended claims. [0126]

Claims (21)

What is claimed is:
1. A system for repairing a lumen, said system comprising:
a graft having a tubular body, a superior end and an inferior end;
a superior attachment system secured to said superior end of said graft and an inferior attachment system secured to said inferior end of said graft, said superior and inferior attachment systems having a first configuration and a second configuration, said first configuration compressed from said second configuration; and
a delivery catheter for placing said graft within the lumen, said delivery catheter having a releasing system, said releasing system including a superior tie to retain said superior attachment system in said first configuration and an inferior tie to retain said inferior attachment system in said first configuration.
2. The system of claim 1, wherein said releasing system further includes at least one release wire cooperating with said superior and inferior ties to retain said superior and inferior attachment systems in said first configuration and to place said superior and inferior attachment systems in said second configuration.
3. The system of claim 2, wherein said delivery catheter includes an anti-elongation wire.
4. The system of claim 3, wherein said delivery catheter includes an inner catheter, an inferior capsule catheter, an inferior capsule assembly attached to said inferior capsule catheter, and a superior capsule assembly, said inner catheter disposed within said inferior capsule assembly, said superior capsule assembly and said inferior capsule catheter;
said inferior capsule catheter, said superior capsule assembly and said inner catheter assembly each adapted to move relative to each other; and
said superior capsule assembly adapted to contain said superior attachment system and said inferior capsule assembly adapted to contain said inferior attachment system.
5. The system of claim 4, wherein said delivery catheter further includes a capsule jacket assembly, said capsule jacket assembly adapted to overlay and move relative to said inferior capsule catheter, said superior capsule assembly and said inner catheter.
6. The system of claim 4, wherein said inner catheter includes a control wire lumen adapted to slidably receive a control wire, said control wire having a distal end secured to said superior capsule assembly.
7. The system of claim 4, wherein said superior capsule assembly includes a flexible and tapered nose cone.
8. The system of claim 4, wherein said inner catheter includes an anti-elongation lumen adapted to receive said anti-elongation wire and at least one notch in communication with said anti-elongation lumen, said anti-elongation wire adapted to exit said anti-elongation lumen through said notch and to be affixed to an exterior of said inner catheter.
9. The system of claim 4, wherein said inner catheter includes a release wire lumen adapted to receive said release wire and at least one notch in communication with said release wire lumen, said release wire exiting said release wire lumen through said at least one notch to engage said tie and to reenter said release wire lumen through said notch.
10. The system of claim 9, wherein said inner catheter includes a conical-shaped knob cooperating with said superior capsule assembly for retracting said superior capsule assembly through said graft.
11. The system of claim 4, wherein said inner catheter includes a release wire lumen, said release wire slidably disposed in said release wire lumen, an inferior notch and a superior notch each in communication with said release wire lumen, said release wire exiting said inferior notch, engaging said inferior tie and reentering said inferior notch, said release wire further exiting said superior notch, engaging said superior tie and reentering said superior notch.
12. The system of claim 11, wherein said superior and inferior ties each include a single suture, each said suture secured at a midpoint to said graft, formed into two loops through which said release wire is threaded and affixed at their ends to said graft.
13. The system of claim 12, wherein each said suture is secured to said graft so that each said suture resides exterior said graft.
14. The system of claim 13, wherein said release wire passes through a wall of said graft near said inferior end of said graft to engage said inferior tie and passes through said wall of said graft near said superior end of said graft to engage said superior tie.
15. The system of claim 13, wherein each said suture is passed through a wall of said graft to engage said release wire.
16. A graft for intraluminal repair of a thoracic aortic aneurysm, comprising:
a hollow tubular body, a superior end and an inferior end, said hollow tubular body having a predetermined diameter, length and wall thickness adapted for intraluminal repair of a thoracic aortic aneurysm.
17. The graft of claim 16, wherein said predetermined diameter ranges from 30-40 mm.
18. The graft of claim 16, wherein said predetermined length ranges from 7-15 cm.
19. The graft of claim 16, wherein said predetermined wall thickness ranges from 0.127 to 0.229 mm.
20. A method for placing a graft within a lumen, which comprises the steps of:
providing a graft having an attachment system secured thereto, said attachment system having a first configuration and a second configuration, said first configuration compressed from said second configuration;
providing a delivery catheter for receiving said graft and for placing said graft within the lumen, said delivery catheter having a releasing system cooperating with said attachment system, said releasing system including a tie and a release wire;
placing said release wire into engagement with said tie;
causing said tie to place said attachment system in said first configuration;
loading said graft within said delivery catheter;
placing said delivery catheter within the lumen;
unloading said graft from said delivery catheter; and
removing said release wire from engagement with said tie to permit said attachment system to assume said second configuration and to engage the lumen.
21. A method for repairing a thoracic aortic aneurysm, which comprises the steps of:
providing a graft having an attachment system secured thereto, said attachment system having a first configuration and a second configuration, said first configuration compressed from said second configuration;
providing a delivery catheter for receiving said graft and for placing said graft within the thoracic aorta, said delivery catheter having a releasing system;
causing said releasing system to retain said attachment system in said first configuration;
loading said graft within said delivery catheter;
placing said delivery catheter within a patient's vasculature;
advancing said delivery catheter to the thoracic aorta;
unloading said graft from said delivery catheters; and
causing said releasing system to permit said attachment system to assume said second configuration and to engage said thoracic aorta.
US10/066,436 1994-12-15 2002-01-30 Graft assembly having support structure Abandoned US20020091439A1 (en)

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US08/358,067 US5693083A (en) 1983-12-09 1994-12-15 Thoracic graft and delivery catheter
US08/931,323 US6346118B1 (en) 1983-12-09 1997-09-16 Thoracic graft and delivery catheter
US10/066,436 US20020091439A1 (en) 1994-12-15 2002-01-30 Graft assembly having support structure

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US08/931,323 Expired - Lifetime US6346118B1 (en) 1983-12-09 1997-09-16 Thoracic graft and delivery catheter
US10/066,436 Abandoned US20020091439A1 (en) 1994-12-15 2002-01-30 Graft assembly having support structure

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Cited By (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040107004A1 (en) * 2002-12-02 2004-06-03 Seedling Enterprises, Llc Bariatric sleeve
WO2004049982A3 (en) * 2002-12-02 2004-10-14 Gi Dynamics Inc Bariatric sleeve
US20040220682A1 (en) * 2003-03-28 2004-11-04 Gi Dynamics, Inc. Anti-obesity devices
US20040241768A1 (en) * 2000-05-08 2004-12-02 Whitten David G. Fluorescent polymer-QTL approach to biosensing
US20040249434A1 (en) * 2001-12-03 2004-12-09 Xtent, Inc. Stent delivery for bifuricated vessels
US20050038502A1 (en) * 2003-08-11 2005-02-17 Igor Waysbeyn Anastomosis system and method
US20050049674A1 (en) * 2003-09-03 2005-03-03 Berra Humberto A. Stent graft
WO2005034811A1 (en) * 2003-10-10 2005-04-21 William Cook Europe Aps Stent graft retention system
US20050125075A1 (en) * 2003-12-09 2005-06-09 Gi Dynamics, Inc. Intestinal sleeve
WO2006016894A1 (en) * 2004-07-09 2006-02-16 Gi Dynamics, Inc. Methods and devices for placing a gastrointestinal sleeve
US20070027526A1 (en) * 2005-07-27 2007-02-01 Cook Critical Care Incorporated Stent/graft device and method for open surgical placement
EP1537836A3 (en) * 2003-12-01 2007-10-03 Cordis Corporation Prosthesis graft with z pleating
DE102006033399A1 (en) * 2006-07-19 2008-01-24 Jotec Gmbh X-ray marker for precise implantation of stents
WO2008047092A1 (en) * 2006-10-16 2008-04-24 Anson Medical Ltd System and method for positioning a stent graft
US20080195191A1 (en) * 2005-05-24 2008-08-14 Qiyi Luo Flexible Stent-Graft
US20090030497A1 (en) * 2007-07-25 2009-01-29 Metcalf Justin M Retention Wire For Self-Expanding Stent
WO2009038949A1 (en) * 2007-09-19 2009-03-26 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
US20090112237A1 (en) * 2007-10-26 2009-04-30 Cook Critical Care Incorporated Vascular conduit and delivery system for open surgical placement
US20090171442A1 (en) * 2007-12-27 2009-07-02 Cook Incorporated Z-stent with incorporated barbs
US20090254170A1 (en) * 2003-04-03 2009-10-08 William A. Cook Australia Pty. Ltd. Branch stent graft deployment and method
US20090264992A1 (en) * 2008-04-17 2009-10-22 Fleming Iii James A Combination barb restraint and stent attachment deployment mechanism
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US20100161605A1 (en) * 2008-12-23 2010-06-24 Yahoo! Inc. Context transfer in search advertising
US20100179642A1 (en) * 2005-06-17 2010-07-15 C.R. Bard, Inc. Vascular Graft With Kink Resistance After Clamping
US7766973B2 (en) 2005-01-19 2010-08-03 Gi Dynamics, Inc. Eversion resistant sleeves
US7771382B2 (en) 2005-01-19 2010-08-10 Gi Dynamics, Inc. Resistive anti-obesity devices
CH700476A1 (en) * 2009-02-23 2010-08-31 Carag Ag Feeding system for feeding or introducing article, particularly stent, into body volume or hollow space, has outer sleeve that is concentrically provided around guiding wire
US7815591B2 (en) 2004-09-17 2010-10-19 Gi Dynamics, Inc. Atraumatic gastrointestinal anchor
US7819836B2 (en) 2006-06-23 2010-10-26 Gi Dynamics, Inc. Resistive anti-obesity devices
US20100286794A1 (en) * 2008-01-10 2010-11-11 Novatech Sa Endoprosthesis for anatomical duct
US7892274B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US7918881B2 (en) 2003-06-09 2011-04-05 Xtent, Inc. Stent deployment systems and methods
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US20110190868A1 (en) * 2008-09-12 2011-08-04 Werner Dieter Ducke Radiopaque reinforcing member
US8016871B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US8016870B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
US8062345B2 (en) 2003-09-03 2011-11-22 Bolton Medical, Inc. Delivery systems for delivering and deploying stent grafts
US8070790B2 (en) 2003-09-03 2011-12-06 Bolton Medical, Inc. Capture device for stent graft delivery
US8083788B2 (en) 2001-12-03 2011-12-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US8137301B2 (en) 2002-12-02 2012-03-20 Gi Dynamics, Inc. Bariatric sleeve
US8157853B2 (en) * 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8177831B2 (en) 2001-12-03 2012-05-15 Xtent, Inc. Stent delivery apparatus and method
US8226710B2 (en) 2005-05-13 2012-07-24 Medtronic Corevalve, Inc. Heart valve prosthesis and methods of manufacture and use
US8257427B2 (en) 2001-09-11 2012-09-04 J.W. Medical Systems, Ltd. Expandable stent
US8282680B2 (en) 2003-01-17 2012-10-09 J. W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US8313524B2 (en) 2004-08-31 2012-11-20 C. R. Bard, Inc. Self-sealing PTFE graft with kink resistance
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8460358B2 (en) 2004-03-30 2013-06-11 J.W. Medical Systems, Ltd. Rapid exchange interventional devices and methods
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US20130190858A1 (en) * 2008-08-29 2013-07-25 Cook Medical Technologies Llc Barbed anchors for wire stent
US8500792B2 (en) 2003-09-03 2013-08-06 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US8574282B2 (en) 2001-12-03 2013-11-05 J.W. Medical Systems Ltd. Apparatus and methods for delivery of braided prostheses
US8585747B2 (en) 2003-12-23 2013-11-19 J.W. Medical Systems Ltd. Devices and methods for controlling and indicating the length of an interventional element
US8636794B2 (en) 2005-11-09 2014-01-28 C. R. Bard, Inc. Grafts and stent grafts having a radiopaque marker
US8652198B2 (en) 2006-03-20 2014-02-18 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US20140052232A1 (en) * 2012-08-10 2014-02-20 Altura Medical, Inc. Handle assemblies for stent graft delivery systems and associated systems and methods
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US8702781B2 (en) 2001-12-03 2014-04-22 J.W. Medical Systems Ltd. Apparatus and methods for delivery of multiple distributed stents
US8769796B2 (en) 2008-09-25 2014-07-08 Advanced Bifurcation Systems, Inc. Selective stent crimping
US8795347B2 (en) 2008-09-25 2014-08-05 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US8801647B2 (en) 2007-02-22 2014-08-12 Gi Dynamics, Inc. Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
US8808347B2 (en) 2008-09-25 2014-08-19 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8979917B2 (en) 2008-09-25 2015-03-17 Advanced Bifurcation Systems, Inc. System and methods for treating a bifurcation
US8980297B2 (en) 2007-02-20 2015-03-17 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US8986362B2 (en) 2004-06-28 2015-03-24 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8984733B2 (en) 2013-02-05 2015-03-24 Artventive Medical Group, Inc. Bodily lumen occlusion
US8998970B2 (en) 2012-04-12 2015-04-07 Bolton Medical, Inc. Vascular prosthetic delivery device and method of use
US9017351B2 (en) 2010-06-29 2015-04-28 Artventive Medical Group, Inc. Reducing flow through a tubular structure
US9095344B2 (en) 2013-02-05 2015-08-04 Artventive Medical Group, Inc. Methods and apparatuses for blood vessel occlusion
US9101506B2 (en) 2009-03-13 2015-08-11 Bolton Medical, Inc. System and method for deploying an endoluminal prosthesis at a surgical site
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
US9149277B2 (en) 2010-10-18 2015-10-06 Artventive Medical Group, Inc. Expandable device delivery
US9149358B2 (en) * 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US20150335426A1 (en) * 2012-12-27 2015-11-26 Transcatheter Technologies Gmbh Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism, implant and method
US9198749B2 (en) 2006-10-12 2015-12-01 C. R. Bard, Inc. Vascular grafts with multiple channels and methods for making
US9247942B2 (en) 2010-06-29 2016-02-02 Artventive Medical Group, Inc. Reversible tubal contraceptive device
US9254210B2 (en) 2011-02-08 2016-02-09 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US9364356B2 (en) 2011-02-08 2016-06-14 Advanced Bifurcation System, Inc. System and methods for treating a bifurcation with a fully crimped stent
US9364314B2 (en) 2008-06-30 2016-06-14 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US9439751B2 (en) 2013-03-15 2016-09-13 Bolton Medical, Inc. Hemostasis valve and delivery systems
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
CN106456150A (en) * 2014-06-16 2017-02-22 库克医药技术有限责任公司 Plunger-driven collet handle and system for fiducial deployment
US9636116B2 (en) 2013-06-14 2017-05-02 Artventive Medical Group, Inc. Implantable luminal devices
US9737306B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Implantable luminal devices
US9737308B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US9737424B2 (en) 2008-09-25 2017-08-22 Advanced Bifurcation Systems, Inc. Partially crimped stent
US9827121B2 (en) 2013-03-15 2017-11-28 Cook Medical Technologies Llc Quick release deployment handle for medical devices
US9877857B2 (en) 2003-09-03 2018-01-30 Bolton Medical, Inc. Sheath capture device for stent graft delivery system and method for operating same
US10149968B2 (en) 2013-06-14 2018-12-11 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
WO2019121889A1 (en) * 2017-12-20 2019-06-27 Koninklijke Philips N.V. Torsional deployment detection of a vascular therapy device
US10363043B2 (en) 2014-05-01 2019-07-30 Artventive Medical Group, Inc. Treatment of incompetent vessels
US10413436B2 (en) 2010-06-13 2019-09-17 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10646365B2 (en) 2003-09-03 2020-05-12 Bolton Medical, Inc. Delivery system and method for self-centering a proximal end of a stent graft
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US10813644B2 (en) 2016-04-01 2020-10-27 Artventive Medical Group, Inc. Occlusive implant and delivery system
US10993803B2 (en) 2011-04-01 2021-05-04 W. L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
US11123174B2 (en) 2012-03-13 2021-09-21 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11129622B2 (en) 2015-05-14 2021-09-28 W. L. Gore & Associates, Inc. Devices and methods for occlusion of an atrial appendage
US11135078B2 (en) 2010-06-13 2021-10-05 Synerz Medical, Inc. Intragastric device for treating obesity
US11173023B2 (en) 2017-10-16 2021-11-16 W. L. Gore & Associates, Inc. Medical devices and anchors therefor
US11259945B2 (en) 2003-09-03 2022-03-01 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US11298252B2 (en) 2008-09-25 2022-04-12 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US11324615B2 (en) 2011-11-14 2022-05-10 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11382781B2 (en) 2011-11-14 2022-07-12 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11457925B2 (en) 2011-09-16 2022-10-04 W. L. Gore & Associates, Inc. Occlusive devices
US11596537B2 (en) 2003-09-03 2023-03-07 Bolton Medical, Inc. Delivery system and method for self-centering a proximal end of a stent graft

Families Citing this family (370)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU722454B2 (en) * 1988-03-09 2000-08-03 Endovascular Technologies, Inc. A securing device for an intraluminal graft
US6682557B1 (en) * 1991-04-11 2004-01-27 Endovascular Technologies, Inc. Bifurcated multicapsule intraluminal grafting system and method
US5591172A (en) * 1991-06-14 1997-01-07 Ams Medinvent S.A. Transluminal implantation device
CA2125258C (en) * 1993-08-05 1998-12-22 Dinah B Quiachon Multicapsule intraluminal grafting system and method
US6039749A (en) 1994-02-10 2000-03-21 Endovascular Systems, Inc. Method and apparatus for deploying non-circular stents and graftstent complexes
US5824044A (en) 1994-05-12 1998-10-20 Endovascular Technologies, Inc. Bifurcated multicapsule intraluminal grafting system
US5683451A (en) * 1994-06-08 1997-11-04 Cardiovascular Concepts, Inc. Apparatus and methods for deployment release of intraluminal prostheses
DE29522101U1 (en) 1994-06-08 1999-12-09 Cardiovascular Concepts Inc Endoluminal prosthesis
US5824041A (en) * 1994-06-08 1998-10-20 Medtronic, Inc. Apparatus and methods for placement and repositioning of intraluminal prostheses
CA2147547C (en) * 1994-08-02 2006-12-19 Peter J. Schmitt Thinly woven flexible graft
AU6862596A (en) * 1995-09-18 1997-04-09 W.L. Gore & Associates, Inc. A delivery system for intraluminal vascular grafts
US5591195A (en) * 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US8728143B2 (en) * 1996-06-06 2014-05-20 Biosensors International Group, Ltd. Endoprosthesis deployment system for treating vascular bifurcations
US7238197B2 (en) * 2000-05-30 2007-07-03 Devax, Inc. Endoprosthesis deployment system for treating vascular bifurcations
US7686846B2 (en) * 1996-06-06 2010-03-30 Devax, Inc. Bifurcation stent and method of positioning in a body lumen
US5954764A (en) 1996-09-20 1999-09-21 Parodi; Juan Carlos Device for concurrently placing an endovascular expander with an endovascular prosthesis
US5972017A (en) 1997-04-23 1999-10-26 Vascular Science Inc. Method of installing tubular medical graft connectors
US6036702A (en) 1997-04-23 2000-03-14 Vascular Science Inc. Medical grafting connectors and fasteners
US5976178A (en) 1996-11-07 1999-11-02 Vascular Science Inc. Medical grafting methods
US5941908A (en) * 1997-04-23 1999-08-24 Vascular Science, Inc. Artificial medical graft with a releasable retainer
US6120432A (en) 1997-04-23 2000-09-19 Vascular Science Inc. Medical grafting methods and apparatus
US6026814A (en) 1997-03-06 2000-02-22 Scimed Life Systems, Inc. System and method for percutaneous coronary artery bypass
US6155264A (en) 1997-03-06 2000-12-05 Scimed Life Systems, Inc. Percutaneous bypass by tunneling through vessel wall
US6035856A (en) 1997-03-06 2000-03-14 Scimed Life Systems Percutaneous bypass with branching vessel
US5824055A (en) * 1997-03-25 1998-10-20 Endotex Interventional Systems, Inc. Stent graft delivery system and methods of use
FR2762989B1 (en) * 1997-05-12 1999-09-03 Braun Celsa Sa SYSTEM FOR REPAIRING AN ANATOMIC DUCT BY A PROGRESSIVE OPENING IMPLANT
AUPO700897A0 (en) * 1997-05-26 1997-06-19 William A Cook Australia Pty Ltd A method and means of deploying a graft
US6092526A (en) 1997-06-19 2000-07-25 Scimed Life Systems, Inc. Percutaneous chamber-to-artery bypass
US6213126B1 (en) 1997-06-19 2001-04-10 Scimed Life Systems, Inc. Percutaneous artery to artery bypass using heart tissue as a portion of a bypass conduit
US6443158B1 (en) 1997-06-19 2002-09-03 Scimed Life Systems, Inc. Percutaneous coronary artery bypass through a venous vessel
US6070589A (en) 1997-08-01 2000-06-06 Teramed, Inc. Methods for deploying bypass graft stents
US6371982B2 (en) 1997-10-09 2002-04-16 St. Jude Medical Cardiovascular Group, Inc. Graft structures with compliance gradients
US6074416A (en) 1997-10-09 2000-06-13 St. Jude Medical Cardiovascular Group, Inc. Wire connector structures for tubular grafts
US6001124A (en) * 1997-10-09 1999-12-14 Vascular Science, Inc. Oblique-angle graft connectors
US6068654A (en) * 1997-12-23 2000-05-30 Vascular Science, Inc. T-shaped medical graft connector
US6048362A (en) * 1998-01-12 2000-04-11 St. Jude Medical Cardiovascular Group, Inc. Fluoroscopically-visible flexible graft structures
US6013190A (en) * 1998-01-21 2000-01-11 Vascular Science Inc. Catheters with integrated lumen and methods of their manufacture and use
US6186986B1 (en) 1998-01-21 2001-02-13 St. Jude Medical Cardiovascular Group, Inc. Micro-catheters and methods of their manufacture
JP4187411B2 (en) 1998-01-30 2008-11-26 セント ジュード メディカル エーティージー, インコーポレイテッド Device for use in closing a septal defect
US6994713B2 (en) 1998-01-30 2006-02-07 St. Jude Medical Atg, Inc. Medical graft connector or plug structures, and methods of making and installing same
US6395019B2 (en) * 1998-02-09 2002-05-28 Trivascular, Inc. Endovascular graft
US6235054B1 (en) 1998-02-27 2001-05-22 St. Jude Medical Cardiovascular Group, Inc. Grafts with suture connectors
US7491232B2 (en) 1998-09-18 2009-02-17 Aptus Endosystems, Inc. Catheter-based fastener implantation apparatus and methods with implantation force resolution
US6129756A (en) * 1998-03-16 2000-10-10 Teramed, Inc. Biluminal endovascular graft system
US6224609B1 (en) 1998-03-16 2001-05-01 Teramed Inc. Bifurcated prosthetic graft
US6001117A (en) * 1998-03-19 1999-12-14 Indigo Medical, Inc. Bellows medical construct and apparatus and method for using same
US6290731B1 (en) 1998-03-30 2001-09-18 Cordis Corporation Aortic graft having a precursor gasket for repairing an abdominal aortic aneurysm
US6656215B1 (en) 2000-11-16 2003-12-02 Cordis Corporation Stent graft having an improved means for attaching a stent to a graft
US6776791B1 (en) * 1998-04-01 2004-08-17 Endovascular Technologies, Inc. Stent and method and device for packing of same
US6325813B1 (en) 1998-08-18 2001-12-04 Scimed Life Systems, Inc. Method and apparatus for stabilizing vascular wall
EP1117341B1 (en) * 1998-09-30 2004-12-29 Bard Peripheral Vascular, Inc. Delivery mechanism for implantable stent
US6273909B1 (en) * 1998-10-05 2001-08-14 Teramed Inc. Endovascular graft system
EP1043041A4 (en) * 1998-10-29 2008-12-17 Kanji Inoue Guiding device of instruments
US6508252B1 (en) 1998-11-06 2003-01-21 St. Jude Medical Atg, Inc. Medical grafting methods and apparatus
US6152937A (en) 1998-11-06 2000-11-28 St. Jude Medical Cardiovascular Group, Inc. Medical graft connector and methods of making and installing same
US6113612A (en) 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
US7018401B1 (en) 1999-02-01 2006-03-28 Board Of Regents, The University Of Texas System Woven intravascular devices and methods for making the same and apparatus for delivery of the same
US8034100B2 (en) * 1999-03-11 2011-10-11 Endologix, Inc. Graft deployment system
US6712836B1 (en) 1999-05-13 2004-03-30 St. Jude Medical Atg, Inc. Apparatus and methods for closing septal defects and occluding blood flow
US6699256B1 (en) 1999-06-04 2004-03-02 St. Jude Medical Atg, Inc. Medical grafting apparatus and methods
US6398802B1 (en) * 1999-06-21 2002-06-04 Scimed Life Systems, Inc. Low profile delivery system for stent and graft deployment
US6533806B1 (en) 1999-10-01 2003-03-18 Scimed Life Systems, Inc. Balloon yielded delivery system and endovascular graft design for easy deployment
US7074235B1 (en) * 1999-10-16 2006-07-11 Sumit Roy Low-profile, non-stented prosthesis for transluminal implantation
US6652567B1 (en) 1999-11-18 2003-11-25 David H. Deaton Fenestrated endovascular graft
US6602263B1 (en) 1999-11-30 2003-08-05 St. Jude Medical Atg, Inc. Medical grafting methods and apparatus
US6280466B1 (en) * 1999-12-03 2001-08-28 Teramed Inc. Endovascular graft system
US6602280B2 (en) 2000-02-02 2003-08-05 Trivascular, Inc. Delivery system and method for expandable intracorporeal device
US20040249436A1 (en) * 2000-05-19 2004-12-09 Aznoian Harold M. Stents and stenting methods
US20030139803A1 (en) * 2000-05-30 2003-07-24 Jacques Sequin Method of stenting a vessel with stent lumenal diameter increasing distally
US6527779B1 (en) * 2000-07-10 2003-03-04 Endotex Interventional Systems, Inc. Stent delivery device
EP1179322A3 (en) * 2000-08-09 2004-02-25 BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin Stent crimping method and device
US20020022860A1 (en) 2000-08-18 2002-02-21 Borillo Thomas E. Expandable implant devices for filtering blood flow from atrial appendages
US6649030B1 (en) 2000-08-31 2003-11-18 Endovascular Technologies, Inc. Physical vapor deposition of radiopaque markings on a graft
US20030050684A1 (en) * 2001-09-10 2003-03-13 Abrams Robert M. Internal restraint for delivery of self-expanding stents
US6589273B1 (en) * 2000-10-02 2003-07-08 Impra, Inc. Apparatus and method for relining a blood vessel
US6562064B1 (en) * 2000-10-27 2003-05-13 Vascular Architects, Inc. Placement catheter assembly
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
US20040106972A1 (en) * 2000-11-20 2004-06-03 Deaton David H. Fenestrated endovascular graft
US6733521B2 (en) 2001-04-11 2004-05-11 Trivascular, Inc. Delivery system and method for endovascular graft
US6761733B2 (en) 2001-04-11 2004-07-13 Trivascular, Inc. Delivery system and method for bifurcated endovascular graft
US6676692B2 (en) * 2001-04-27 2004-01-13 Intek Technology L.L.C. Apparatus for delivering, repositioning and/or retrieving self-expanding stents
EP1387638A2 (en) * 2001-05-14 2004-02-11 St. Jude Medical ATG, Inc. Medical grafting methods and apparatus
US7338514B2 (en) 2001-06-01 2008-03-04 St. Jude Medical, Cardiology Division, Inc. Closure devices, related delivery methods and tools, and related methods of use
US6911016B2 (en) * 2001-08-06 2005-06-28 Scimed Life Systems, Inc. Guidewire extension system
US6675809B2 (en) 2001-08-27 2004-01-13 Richard S. Stack Satiation devices and methods
AUPR748801A0 (en) * 2001-09-04 2001-09-27 Stentco Llc A stent
WO2003045283A1 (en) * 2001-11-28 2003-06-05 Aptus Endosystems, Inc. Endovascular aneurysm repair system
US9320503B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
US7147657B2 (en) * 2003-10-23 2006-12-12 Aptus Endosystems, Inc. Prosthesis delivery systems and methods
US20050177180A1 (en) * 2001-11-28 2005-08-11 Aptus Endosystems, Inc. Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ
US20110087320A1 (en) * 2001-11-28 2011-04-14 Aptus Endosystems, Inc. Devices, Systems, and Methods for Prosthesis Delivery and Implantation, Including a Prosthesis Assembly
US20070073389A1 (en) * 2001-11-28 2007-03-29 Aptus Endosystems, Inc. Endovascular aneurysm devices, systems, and methods
US8231639B2 (en) 2001-11-28 2012-07-31 Aptus Endosystems, Inc. Systems and methods for attaching a prosthesis within a body lumen or hollow organ
DE60221289T2 (en) 2001-11-29 2008-04-10 Cook Inc., Bloomington FEEDING SYSTEM FOR MEDICAL DEVICES
US7125464B2 (en) * 2001-12-20 2006-10-24 Boston Scientific Santa Rosa Corp. Method for manufacturing an endovascular graft section
US6682537B2 (en) 2001-12-20 2004-01-27 The Cleveland Clinic Foundation Apparatus and method for capturing a wire in a blood vessel
US7014653B2 (en) * 2001-12-20 2006-03-21 Cleveland Clinic Foundation Furcated endovascular prosthesis
US20100016943A1 (en) 2001-12-20 2010-01-21 Trivascular2, Inc. Method of delivering advanced endovascular graft
US6641606B2 (en) 2001-12-20 2003-11-04 Cleveland Clinic Foundation Delivery system and method for deploying an endovascular prosthesis
US6989024B2 (en) * 2002-02-28 2006-01-24 Counter Clockwise, Inc. Guidewire loaded stent for delivery through a catheter
EP1494611A2 (en) 2002-03-11 2005-01-12 John L. Wardle Surgical coils and methods of deploying
US8328877B2 (en) 2002-03-19 2012-12-11 Boston Scientific Scimed, Inc. Stent retention element and related methods
US7976564B2 (en) 2002-05-06 2011-07-12 St. Jude Medical, Cardiology Division, Inc. PFO closure devices and related methods of use
CA2486390C (en) * 2002-05-29 2011-01-04 William A. Cook Australia Pty. Ltd. Trigger wire system for a prosthesis deployment device
DE60318850T2 (en) * 2002-06-28 2009-01-22 Cook Inc., Bloomington THORACAL STORAGE DEVICE
AU2003258976B2 (en) * 2002-06-28 2008-05-29 Cook Incorporated Thoracic aortic aneurysm stent graft.
AU2003265587A1 (en) * 2002-08-22 2004-03-11 Cook Incorporated Guide wire
AU2003273274B2 (en) * 2002-09-02 2008-02-28 Cook Incorporated Branch grafting device and method
AU2002951147A0 (en) * 2002-09-02 2002-09-19 Cook Incorporated Branch grafting device and method
GB0220340D0 (en) * 2002-09-02 2002-10-09 Anson Medical Ltd Flexible stent-graft
US8518096B2 (en) * 2002-09-03 2013-08-27 Lifeshield Sciences Llc Elephant trunk thoracic endograft and delivery system
EP1567087B1 (en) 2002-11-08 2009-04-01 Jacques Seguin Endoprosthesis for vascular bifurcation
US7198636B2 (en) * 2003-01-17 2007-04-03 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
US20060058866A1 (en) * 2003-01-17 2006-03-16 Cully Edward H Deployment system for an expandable device
US7753945B2 (en) * 2003-01-17 2010-07-13 Gore Enterprise Holdings, Inc. Deployment system for an endoluminal device
US7611528B2 (en) * 2003-01-24 2009-11-03 Medtronic Vascular, Inc. Stent-graft delivery system
EP1596761B1 (en) * 2003-02-14 2015-06-17 Salviac Limited Stent delivery and deployment system
US20040193141A1 (en) * 2003-02-14 2004-09-30 Leopold Eric W. Intravascular flow modifier and reinforcement device and deployment system for same
ES2346059T3 (en) * 2003-03-26 2010-10-08 Biosensors International Group Ltd. IMPLANT SUPPLY CATHETER WITH ELECTROLYTICALLY EROSIONABLE JOINTS.
US7771463B2 (en) * 2003-03-26 2010-08-10 Ton Dai T Twist-down implant delivery technologies
US20040193179A1 (en) * 2003-03-26 2004-09-30 Cardiomind, Inc. Balloon catheter lumen based stent delivery systems
US20050209672A1 (en) * 2004-03-02 2005-09-22 Cardiomind, Inc. Sliding restraint stent delivery systems
US8372112B2 (en) 2003-04-11 2013-02-12 St. Jude Medical, Cardiology Division, Inc. Closure devices, related delivery methods, and related methods of use
US20040267306A1 (en) 2003-04-11 2004-12-30 Velocimed, L.L.C. Closure devices, related delivery methods, and related methods of use
US7758630B2 (en) * 2003-04-14 2010-07-20 Tryton Medical, Inc. Helical ostium support for treating vascular bifurcations
US7731747B2 (en) 2003-04-14 2010-06-08 Tryton Medical, Inc. Vascular bifurcation prosthesis with multiple thin fronds
US8109987B2 (en) * 2003-04-14 2012-02-07 Tryton Medical, Inc. Method of treating a lumenal bifurcation
US8083791B2 (en) * 2003-04-14 2011-12-27 Tryton Medical, Inc. Method of treating a lumenal bifurcation
US7717953B2 (en) * 2004-10-13 2010-05-18 Tryton Medical, Inc. Delivery system for placement of prosthesis at luminal OS
WO2004112615A2 (en) * 2003-06-16 2004-12-29 Galdonik Jason A Temporary hemostatic plug apparatus and method of use
WO2005020856A2 (en) * 2003-09-02 2005-03-10 Abbott Laboratories Delivery system for a medical device
US7780716B2 (en) * 2003-09-02 2010-08-24 Abbott Laboratories Delivery system for a medical device
US7794489B2 (en) * 2003-09-02 2010-09-14 Abbott Laboratories Delivery system for a medical device
US7235083B1 (en) 2003-09-10 2007-06-26 Endovascular Technologies, Inc. Methods and devices for aiding in situ assembly of repair devices
US7651519B2 (en) * 2003-09-16 2010-01-26 Cook Incorporated Prosthesis deployment system
US7425219B2 (en) * 2003-10-10 2008-09-16 Arshad Quadri System and method for endoluminal grafting of bifurcated and branched vessels
WO2005037141A2 (en) 2003-10-14 2005-04-28 William A. Cook Australia Pty. Ltd. Introducer for an iliac side branch device
US7998186B2 (en) 2003-10-14 2011-08-16 William A. Cook Australia Pty. Ltd. Introducer for a side branch device
US20050125050A1 (en) * 2003-12-04 2005-06-09 Wilson Cook Medical Incorporated Biliary stent introducer system
US7347863B2 (en) 2004-05-07 2008-03-25 Usgi Medical, Inc. Apparatus and methods for manipulating and securing tissue
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US20120041550A1 (en) 2003-12-23 2012-02-16 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
WO2005062980A2 (en) 2003-12-23 2005-07-14 Sadra Medical, Inc. Repositionable heart valve
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8287584B2 (en) 2005-11-14 2012-10-16 Sadra Medical, Inc. Medical implant deployment tool
US7824442B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US7651521B2 (en) * 2004-03-02 2010-01-26 Cardiomind, Inc. Corewire actuated delivery system with fixed distal stent-carrying extension
US7449027B2 (en) * 2004-03-29 2008-11-11 Cook Incorporated Modifying fluid flow in a body vessel lumen to promote intraluminal flow-sensitive processes
US20050273150A1 (en) * 2004-03-31 2005-12-08 Howell Douglas D Stent introducer system
US8465536B2 (en) * 2004-04-06 2013-06-18 Cook Medical Technologies Llc Prosthesis deployment system
US8257394B2 (en) 2004-05-07 2012-09-04 Usgi Medical, Inc. Apparatus and methods for positioning and securing anchors
US8444657B2 (en) 2004-05-07 2013-05-21 Usgi Medical, Inc. Apparatus and methods for rapid deployment of tissue anchors
US8834355B2 (en) * 2004-05-25 2014-09-16 U.S. Endoscopy Group, Inc. Delivery device
AU2005262541B2 (en) * 2004-06-16 2011-04-21 Cook Incorporated Thoracic deployment device and stent graft
US20060129181A1 (en) * 2004-12-13 2006-06-15 Callol Joseph R Retrieval device with retractable dilator tip
WO2008098255A2 (en) 2007-02-09 2008-08-14 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US7731705B2 (en) * 2005-01-10 2010-06-08 Wardle John L Eluting coils and methods of deploying and retrieving
US8287583B2 (en) 2005-01-10 2012-10-16 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20060155366A1 (en) * 2005-01-10 2006-07-13 Laduca Robert Apparatus and method for deploying an implantable device within the body
US8128680B2 (en) 2005-01-10 2012-03-06 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US7736331B2 (en) * 2005-03-11 2010-06-15 Merit Medical Systems, Inc. Drainage catheter hub with welded suture and sidewall stylet
US7641630B2 (en) * 2005-03-11 2010-01-05 Merit Medical Systems, Inc. Drainage catheter hub with locking cam
US20060212009A1 (en) * 2005-03-16 2006-09-21 Accisano Nicholas G Iii Drainage catheter hub with rotatable lever handle
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
EP1883371B1 (en) * 2005-05-25 2015-10-07 Covidien LP System and method for delivering and deploying and occluding device within a vessel
US8298291B2 (en) * 2005-05-26 2012-10-30 Usgi Medical, Inc. Methods and apparatus for securing and deploying tissue anchors
US20070073379A1 (en) * 2005-09-29 2007-03-29 Chang Jean C Stent delivery system
JP4627687B2 (en) * 2005-06-20 2011-02-09 Junken Medical株式会社 Stent insertion device
WO2007005799A1 (en) * 2005-06-30 2007-01-11 Abbott Laboratories Delivery system for a medical device
US7578814B2 (en) * 2005-08-05 2009-08-25 Merit Medical Systems, Inc. Drainage catheter with lockable hub
US7824367B2 (en) * 2005-08-17 2010-11-02 Merit Medical Systems, Inc. Drainage catheter with locking hub
EP1922029B1 (en) * 2005-08-18 2014-11-19 Cook Medical Technologies LLC Assembly of stent grafts
US7712606B2 (en) 2005-09-13 2010-05-11 Sadra Medical, Inc. Two-part package for medical implant
CN101466316B (en) 2005-10-20 2012-06-27 阿普特斯内系统公司 Devices systems and methods for prosthesis delivery and implantation including the use of a fastener tool
US20070100414A1 (en) * 2005-11-02 2007-05-03 Cardiomind, Inc. Indirect-release electrolytic implant delivery systems
WO2007054015A1 (en) * 2005-11-09 2007-05-18 Ning Wen An artificial heart valve stent and weaving method thereof
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CA2936205C (en) 2006-01-13 2018-08-21 C.R. Bard, Inc. Stent delivery system
US11026822B2 (en) 2006-01-13 2021-06-08 C. R. Bard, Inc. Stent delivery system
FR2896405B1 (en) 2006-01-24 2008-04-18 Perouse Soc Par Actions Simpli DEVICE FOR TREATING A BLOOD CIRCULATION CONDUIT AND METHOD OF PREPARING THE SAME
CN101415379B (en) 2006-02-14 2012-06-20 萨德拉医学公司 Systems for delivering a medical implant
CN101045022B (en) * 2006-03-30 2010-08-25 温宁 Self-expanding stent axial wire-drawing tensioning mechanism
US20110071455A1 (en) * 2006-04-06 2011-03-24 Beane Richard M Method and apparatus for suturelessly connecting a conduit to a hollow organ
GB0615658D0 (en) 2006-08-07 2006-09-13 Angiomed Ag Hand-held actuator device
US9233226B2 (en) * 2006-08-22 2016-01-12 Merit Medical Systems, Inc. Drainage catheter with pig-tail straightener
US20080071343A1 (en) * 2006-09-15 2008-03-20 Kevin John Mayberry Multi-segmented graft deployment system
EP2066270B1 (en) * 2006-09-28 2011-09-07 Med Institute, Inc. Endovascular delivery device
BRPI0717392A2 (en) 2006-10-22 2013-10-15 Idev Technologies Inc METHODS FOR FIXING WIRE END AND RESULTING DEVICES
WO2008051941A2 (en) * 2006-10-22 2008-05-02 Idev Technologies, Inc. Devices and methods for stent advancement
US9278017B2 (en) 2006-11-30 2016-03-08 Cook Medical Technologies Llc Implant release mechanism
CN101605509B (en) * 2006-12-15 2012-09-19 生物传感器国际集团有限公司 Stent systems
US8070799B2 (en) 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US20080147181A1 (en) 2006-12-19 2008-06-19 Sorin Biomedica Cardio S.R.L. Device for in situ axial and radial positioning of cardiac valve prostheses
BRPI0807260A2 (en) 2007-02-09 2014-06-10 Taheri Laduca Llc "IMPLANTABLE STENT AND METHOD OF MANUFACTURING A TUBULAR GRAFT"
EP2144580B1 (en) * 2007-04-09 2015-08-12 Covidien LP Stent delivery system
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US20080262590A1 (en) * 2007-04-19 2008-10-23 Medtronic Vascular, Inc. Delivery System for Stent-Graft
US7766953B2 (en) * 2007-05-16 2010-08-03 Med Institute, Inc. Deployment system for an expandable stent
US20080300667A1 (en) * 2007-05-31 2008-12-04 Bay Street Medical System for delivering a stent
GB0713497D0 (en) 2007-07-11 2007-08-22 Angiomed Ag Device for catheter sheath retraction
US9149379B2 (en) * 2007-07-16 2015-10-06 Cook Medical Technologies Llc Delivery device
US8808367B2 (en) 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US8114154B2 (en) * 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
US20090105794A1 (en) * 2007-09-07 2009-04-23 Ziarno W Andrew Microprocessor controlled delivery system for cardiac valve prosthesis
US8066755B2 (en) 2007-09-26 2011-11-29 Trivascular, Inc. System and method of pivoted stent deployment
US8226701B2 (en) 2007-09-26 2012-07-24 Trivascular, Inc. Stent and delivery system for deployment thereof
US8663309B2 (en) 2007-09-26 2014-03-04 Trivascular, Inc. Asymmetric stent apparatus and method
WO2009046372A2 (en) 2007-10-04 2009-04-09 Trivascular2, Inc. Modular vascular graft for low profile percutaneous delivery
CN101868199B (en) 2007-10-12 2016-04-06 斯波瑞申有限公司 valve loader method, system and equipment
US8043301B2 (en) * 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
US8114144B2 (en) 2007-10-17 2012-02-14 Abbott Cardiovascular Systems Inc. Rapid-exchange retractable sheath self-expanding delivery system with incompressible inner member and flexible distal assembly
US8328861B2 (en) 2007-11-16 2012-12-11 Trivascular, Inc. Delivery system and method for bifurcated graft
US8083789B2 (en) 2007-11-16 2011-12-27 Trivascular, Inc. Securement assembly and method for expandable endovascular device
US9180030B2 (en) 2007-12-26 2015-11-10 Cook Medical Technologies Llc Low profile non-symmetrical stent
US8574284B2 (en) 2007-12-26 2013-11-05 Cook Medical Technologies Llc Low profile non-symmetrical bare alignment stents with graft
GB2476451A (en) * 2009-11-19 2011-06-29 Cook William Europ Stent Graft
GB2475494B (en) 2009-11-18 2011-11-23 Cook William Europ Stent graft and introducer assembly
US9226813B2 (en) 2007-12-26 2016-01-05 Cook Medical Technologies Llc Low profile non-symmetrical stent
WO2009091509A1 (en) * 2008-01-16 2009-07-23 St. Jude Medical, Inc. Delivery and retrieval systems for collapsible/expandable prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
WO2009105699A1 (en) 2008-02-22 2009-08-27 Endologix, Inc. Design and method of placement of a graft or graft system
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
BR112012021347A2 (en) 2008-02-26 2019-09-24 Jenavalve Tecnology Inc stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US8313525B2 (en) * 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
WO2009146128A1 (en) * 2008-04-03 2009-12-03 William Cook Europe Aps Implant release mechanism
US20100049293A1 (en) * 2008-06-04 2010-02-25 Zukowski Stanislaw L Controlled deployable medical device and method of making the same
CA2727000C (en) * 2008-06-04 2014-01-07 Gore Enterprise Holdings, Inc. Controlled deployable medical device and method of making the same
DE102008002472A1 (en) * 2008-06-17 2009-12-24 Biotronik Vi Patent Ag A medical device delivery system and method for operating a medical device delivery system
EP2317958B1 (en) * 2008-08-26 2012-02-29 William A. Cook Australia Pty. Ltd. Thoracic introducer
ES2627860T3 (en) 2008-10-10 2017-07-31 Boston Scientific Scimed, Inc. Medical devices and placement systems for placing medical devices
CA2740867C (en) 2008-10-16 2018-06-12 Aptus Endosystems, Inc. Devices, systems, and methods for endovascular staple and/or prosthesis delivery and implantation
US11376114B2 (en) 2008-10-31 2022-07-05 Cook Medical Technologies Llc Introducer for deploying a stent graft in a curved lumen and stent graft therefor
GB2464978B (en) * 2008-10-31 2010-10-20 Cook William Europ Introducer for deploying a stent graft in a curved lumen
GB2464977B (en) * 2008-10-31 2010-11-03 William Cook Europe As Introducer for deploying a stent graft in a curved lumen and stent graft therefor
AU2009335031B2 (en) * 2008-12-30 2013-07-25 Cook Medical Technologies Llc Delivery device
US8858610B2 (en) 2009-01-19 2014-10-14 W. L. Gore & Associates, Inc. Forced deployment sequence
AU2009200350B1 (en) * 2009-02-02 2009-07-16 Cook Incorporated Preloaded stent graft delivery device
US20110054586A1 (en) * 2009-04-28 2011-03-03 Endologix, Inc. Apparatus and method of placement of a graft or graft system
US9168105B2 (en) 2009-05-13 2015-10-27 Sorin Group Italia S.R.L. Device for surgical interventions
US8403982B2 (en) 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US8353953B2 (en) 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
US8657870B2 (en) * 2009-06-26 2014-02-25 Biosensors International Group, Ltd. Implant delivery apparatus and methods with electrolytic release
US8382818B2 (en) * 2009-07-02 2013-02-26 Tryton Medical, Inc. Ostium support for treating vascular bifurcations
US9339631B2 (en) * 2009-09-25 2016-05-17 Boston Scientific Scimed, Inc. Locking mechanism for a medical device
AU2010319903B2 (en) 2009-10-29 2013-07-11 Cook Medical Technologies Llc Stent delivery system with nitinol trigger wire
US9757263B2 (en) 2009-11-18 2017-09-12 Cook Medical Technologies Llc Stent graft and introducer assembly
WO2011081997A1 (en) * 2009-12-30 2011-07-07 Wilson-Cook Medical Inc. Proximal release delivery device
DK2528553T3 (en) * 2010-01-29 2018-01-22 Cook Medical Technologies Llc MECHANICAL EXPANDABLE INTRODUCTION AND DILATION SYSTEMS
US20110218609A1 (en) * 2010-02-10 2011-09-08 Trivascular, Inc. Fill tube manifold and delivery methods for endovascular graft
DE102010008382A1 (en) 2010-02-17 2011-08-18 Transcatheter Technologies GmbH, 93053 A method of crimping or folding a medical implant on a device for introducing or introducing same using zero-pressure crimping and devices
US8454682B2 (en) 2010-04-13 2013-06-04 Medtronic Vascular, Inc. Anchor pin stent-graft delivery system
US8663305B2 (en) 2010-04-20 2014-03-04 Medtronic Vascular, Inc. Retraction mechanism and method for graft cover retraction
AU2010201676B1 (en) * 2010-04-23 2010-07-22 Cook Medical Technologies Llc Curve forming stent graft
US8623064B2 (en) 2010-04-30 2014-01-07 Medtronic Vascular, Inc. Stent graft delivery system and method of use
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
US9023095B2 (en) 2010-05-27 2015-05-05 Idev Technologies, Inc. Stent delivery system with pusher assembly
US9561102B2 (en) 2010-06-02 2017-02-07 Medtronic, Inc. Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve
AU2011282909B2 (en) 2010-07-30 2013-09-12 Cook Medical Technologies Llc Controlled release and recapture prosthetic deployment device
EP2613737B2 (en) 2010-09-10 2023-03-15 Symetis SA Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
GB201017834D0 (en) 2010-10-21 2010-12-01 Angiomed Ag System to deliver a bodily implant
WO2012058104A1 (en) * 2010-10-28 2012-05-03 Cook Medical Technologies Llc Torsion constrained stent delivery system
EP2635241B1 (en) 2010-11-02 2019-02-20 Endologix, Inc. Apparatus for placement of a graft or graft system
US9707108B2 (en) 2010-11-24 2017-07-18 Tryton Medical, Inc. Support for treating vascular bifurcations
US9198787B2 (en) * 2010-12-31 2015-12-01 Cook Medical Technologies Llc Conformable prosthesis delivery system and method for deployment thereof
EP2688516B1 (en) 2011-03-21 2022-08-17 Cephea Valve Technologies, Inc. Disk-based valve apparatus
US8784474B2 (en) 2011-04-21 2014-07-22 Cook Medical Technologies Llc Emergency vascular repair system and method
EP2520251A1 (en) 2011-05-05 2012-11-07 Symetis SA Method and Apparatus for Compressing Stent-Valves
US20120303048A1 (en) 2011-05-24 2012-11-29 Sorin Biomedica Cardio S.R.I. Transapical valve replacement
US10117765B2 (en) * 2011-06-14 2018-11-06 W.L. Gore Associates, Inc Apposition fiber for use in endoluminal deployment of expandable implants
CA2835893C (en) 2011-07-12 2019-03-19 Boston Scientific Scimed, Inc. Coupling system for medical devices
WO2013028605A1 (en) 2011-08-22 2013-02-28 Cook Medical Technologies Llc Emergency vessel repair prosthesis deployment system
US8734500B2 (en) * 2011-09-27 2014-05-27 DePuy Synthes Products, LLC Distal detachment mechanisms for vascular devices
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
US10172708B2 (en) 2012-01-25 2019-01-08 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
US8992595B2 (en) 2012-04-04 2015-03-31 Trivascular, Inc. Durable stent graft with tapered struts and stable delivery methods and devices
US9498363B2 (en) 2012-04-06 2016-11-22 Trivascular, Inc. Delivery catheter for endovascular device
WO2013162724A1 (en) 2012-04-26 2013-10-31 Tryton Medical, Inc. Support for treating vascular bifurcations
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
US9855129B2 (en) * 2012-10-31 2018-01-02 Cook Medical Technologies Llc Multi-level suture attachments for coupling a stent to graft material
US9622893B2 (en) 2012-12-20 2017-04-18 Cook Medical Technologies Llc Apparatus and method for improved deployment of endovascular grafts
US9308108B2 (en) 2013-03-13 2016-04-12 Cook Medical Technologies Llc Controlled release and recapture stent-deployment device
WO2014159116A1 (en) 2013-03-14 2014-10-02 Spiration, Inc. Valve loader method, system, and apparatus
US11911258B2 (en) 2013-06-26 2024-02-27 W. L. Gore & Associates, Inc. Space filling devices
US11291452B2 (en) * 2013-06-26 2022-04-05 W. L. Gore & Associates, Inc. Medical device deployment system
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
CN105491978A (en) 2013-08-30 2016-04-13 耶拿阀门科技股份有限公司 Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
CZ2013698A3 (en) * 2013-09-16 2015-07-15 Ella-Cs, S.R.O. Device for introducing implant
AU2013257415B1 (en) * 2013-11-08 2014-06-26 Cook Medical Technologies Llc An endograft introducer and a capsule assembly for an endograft introducer
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
WO2016093877A1 (en) 2014-12-09 2016-06-16 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
US10016293B2 (en) * 2014-12-29 2018-07-10 Cook Medical Technologies Llc Prosthesis delivery systems having an atraumatic tip for use with trigger wires
US10092428B2 (en) * 2014-12-30 2018-10-09 Cook Medical Technologies Llc Low profile prosthesis delivery device
WO2016115375A1 (en) 2015-01-16 2016-07-21 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
EP3632378A1 (en) 2015-05-01 2020-04-08 JenaValve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
EP3294221B1 (en) 2015-05-14 2024-03-06 Cephea Valve Technologies, Inc. Replacement mitral valves
US10849746B2 (en) 2015-05-14 2020-12-01 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US11129737B2 (en) 2015-06-30 2021-09-28 Endologix Llc Locking assembly for coupling guidewire to delivery system
US10335277B2 (en) 2015-07-02 2019-07-02 Boston Scientific Scimed Inc. Adjustable nosecone
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10779940B2 (en) 2015-09-03 2020-09-22 Boston Scientific Scimed, Inc. Medical device handle
CN108156803B (en) * 2015-09-18 2021-05-04 泰尔茂株式会社 Pushable implant delivery system
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
US10610393B2 (en) 2016-03-24 2020-04-07 Cook Medical Technologies Llc Wire retention and release mechanisms
US10022255B2 (en) 2016-04-11 2018-07-17 Idev Technologies, Inc. Stent delivery system having anisotropic sheath
US10245136B2 (en) 2016-05-13 2019-04-02 Boston Scientific Scimed Inc. Containment vessel with implant sheathing guide
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
US11065138B2 (en) 2016-05-13 2021-07-20 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
GB2550938B (en) * 2016-06-01 2018-07-11 Cook Medical Technologies Llc Medical device introducer assembly particularly for branched medical devices
US11331187B2 (en) 2016-06-17 2022-05-17 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
US10433991B2 (en) 2016-07-18 2019-10-08 Cook Medical Technologies Llc Controlled expansion stent graft delivery system
US10828152B2 (en) 2016-08-11 2020-11-10 4C Medical Technologies, Inc. Heart chamber prosthetic valve implant with base, spring and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function
US10765545B2 (en) 2016-10-31 2020-09-08 Cook Medical Technologies Llc Suture esophageal stent introducer
US11246727B2 (en) 2016-10-31 2022-02-15 Cook Medical Technologies Llc Suture esophageal stent introducer
US11413175B2 (en) 2016-10-31 2022-08-16 Cook Medical Technologies Llc Tube and suture stent introducer system
EP3531987B1 (en) * 2016-10-31 2023-03-01 Cook Medical Technologies LLC Suture esophageal stent introducer
US11141298B2 (en) 2016-10-31 2021-10-12 Cook Medical Technologies Llc Suture esophageal stent introducer
US11141299B2 (en) 2016-10-31 2021-10-12 Cook Medical Technologies Llc Suture esophageal stent introducer
US10849775B2 (en) 2016-10-31 2020-12-01 Cook Medical Technologies Llc Suture esophageal stent introducer parallel handle
US10500080B2 (en) * 2016-10-31 2019-12-10 Cook Medical Technologies Llc Suture esophageal stent introducer
US10702408B2 (en) 2016-10-31 2020-07-07 Cook Medical Technologies Llc Suture esophageal stent introducer
CA3051272C (en) 2017-01-23 2023-08-22 Cephea Valve Technologies, Inc. Replacement mitral valves
EP4209196A1 (en) 2017-01-23 2023-07-12 Cephea Valve Technologies, Inc. Replacement mitral valves
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
US10709541B2 (en) 2017-04-28 2020-07-14 Cook Medical Technologies Llc Systems and methods for adjusting the diameter of an endoluminal prosthesis and an endoluminal prosthesis configured for the same
EP3634311A1 (en) 2017-06-08 2020-04-15 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
EP3661458A1 (en) 2017-08-01 2020-06-10 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10939996B2 (en) 2017-08-16 2021-03-09 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11096810B2 (en) 2017-11-29 2021-08-24 Cook Medical Technologies Llc Preloaded pusher tip for endografts
JP7047106B2 (en) 2018-01-19 2022-04-04 ボストン サイエンティフィック サイムド,インコーポレイテッド Medical device delivery system with feedback loop
WO2019144069A2 (en) 2018-01-19 2019-07-25 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
WO2019157156A1 (en) 2018-02-07 2019-08-15 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
WO2019165394A1 (en) 2018-02-26 2019-08-29 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
WO2019222367A1 (en) 2018-05-15 2019-11-21 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
EP3796873B1 (en) 2018-05-23 2022-04-27 Corcym S.r.l. A cardiac valve prosthesis
WO2019241477A1 (en) 2018-06-13 2019-12-19 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US11857441B2 (en) 2018-09-04 2024-01-02 4C Medical Technologies, Inc. Stent loading device
WO2020123486A1 (en) 2018-12-10 2020-06-18 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
CN113747863A (en) * 2019-03-08 2021-12-03 内奥瓦斯克迪亚拉公司 Retrievable prosthesis delivery system
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
GB2605559B (en) 2021-01-07 2023-04-05 Cook Medical Technologies Llc Stent graft
EP4316430A1 (en) * 2021-03-30 2024-02-07 SB-Kawasumi Laboratories, Inc. Indwelling device

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3805301A (en) * 1972-07-28 1974-04-23 Meadox Medicals Inc Tubular grafts having indicia thereon
DE2452933C3 (en) * 1974-11-07 1979-03-22 Siemens Ag, 1000 Berlin Und 8000 Muenchen Calibration generator for generating pulses with an exponential curve for a signal shaping element
US4140126A (en) * 1977-02-18 1979-02-20 Choudhury M Hasan Method for performing aneurysm repair
US4190909A (en) * 1978-03-31 1980-03-04 Ablaza Sariel G G Apparatus and method for surgical repair of dissecting thoracic aneurysms and the like
SE445884B (en) * 1982-04-30 1986-07-28 Medinvent Sa DEVICE FOR IMPLANTATION OF A RODFORM PROTECTION
US4787899A (en) * 1983-12-09 1988-11-29 Lazarus Harrison M Intraluminal graft device, system and method
US5104399A (en) 1986-12-10 1992-04-14 Endovascular Technologies, Inc. Artificial graft and implantation method
US5275622A (en) * 1983-12-09 1994-01-04 Harrison Medical Technologies, Inc. Endovascular grafting apparatus, system and method and devices for use therewith
US4617932A (en) * 1984-04-25 1986-10-21 Elliot Kornberg Device and method for performing an intraluminal abdominal aortic aneurysm repair
US4681110A (en) * 1985-12-02 1987-07-21 Wiktor Dominik M Catheter arrangement having a blood vessel liner, and method of using it
US4878906A (en) * 1986-03-25 1989-11-07 Servetus Partnership Endoprosthesis for repairing a damaged vessel
IT1202558B (en) 1987-02-17 1989-02-09 Alberto Arpesani INTERNAL PROSTHESIS FOR THE REPLACEMENT OF A PART OF THE HUMAN BODY PARTICULARLY IN THE VASCULAR OPERATIONS
US4872874A (en) * 1987-05-29 1989-10-10 Taheri Syde A Method and apparatus for transarterial aortic graft insertion and implantation
US4830003A (en) * 1988-06-17 1989-05-16 Wolff Rodney G Compressive stent and delivery system
US4913141A (en) * 1988-10-25 1990-04-03 Cordis Corporation Apparatus and method for placement of a stent within a subject vessel
US4950227A (en) * 1988-11-07 1990-08-21 Boston Scientific Corporation Stent delivery system
US5078726A (en) * 1989-02-01 1992-01-07 Kreamer Jeffry W Graft stent and method of repairing blood vessels
US5178634A (en) * 1989-03-31 1993-01-12 Wilson Ramos Martinez Aortic valved tubes for human implants
US4957669A (en) * 1989-04-06 1990-09-18 Shiley, Inc. Method for producing tubing useful as a tapered vascular graft prosthesis
US5207695A (en) * 1989-06-19 1993-05-04 Trout Iii Hugh H Aortic graft, implantation device, and method for repairing aortic aneurysm
JPH067843B2 (en) * 1990-02-15 1994-02-02 寛治 井上 Artificial blood vessel with frame
US5071407A (en) * 1990-04-12 1991-12-10 Schneider (U.S.A.) Inc. Radially expandable fixation member
US5078720A (en) * 1990-05-02 1992-01-07 American Medical Systems, Inc. Stent placement instrument and method
GB2245495A (en) * 1990-05-11 1992-01-08 John Stanley Webber Artery support insertion instrument
WO1992003107A1 (en) * 1990-08-28 1992-03-05 Meadox Medicals, Inc. Self-supporting woven vascular graft
CA2052981C (en) * 1990-10-09 1995-08-01 Cesare Gianturco Percutaneous stent assembly
CA2060067A1 (en) * 1991-01-28 1992-07-29 Lilip Lau Stent delivery system
US5282847A (en) * 1991-02-28 1994-02-01 Medtronic, Inc. Prosthetic vascular grafts with a pleated structure
CA2202800A1 (en) * 1991-04-11 1992-10-12 Alec A. Piplani Endovascular graft having bifurcation and apparatus and method for deploying the same
US5628783A (en) * 1991-04-11 1997-05-13 Endovascular Technologies, Inc. Bifurcated multicapsule intraluminal grafting system and method
US5151105A (en) * 1991-10-07 1992-09-29 Kwan Gett Clifford Collapsible vessel sleeve implant
US5387235A (en) * 1991-10-25 1995-02-07 Cook Incorporated Expandable transluminal graft prosthesis for repair of aneurysm
US5123919A (en) * 1991-11-21 1992-06-23 Carbomedics, Inc. Combined prosthetic aortic heart valve and vascular graft
US5316023A (en) * 1992-01-08 1994-05-31 Expandable Grafts Partnership Method for bilateral intra-aortic bypass
US5405378A (en) * 1992-05-20 1995-04-11 Strecker; Ernst P. Device with a prosthesis implantable in the body of a patient
EP0637745A4 (en) * 1993-02-25 1998-01-14 Nikkiso Co Ltd Automatic inspection apparatus for fish eye in resin, and apparatus and method for producing resin sheet for inspection.
AU689094B2 (en) * 1993-04-22 1998-03-26 C.R. Bard Inc. Non-migrating vascular prosthesis and minimally invasive placement system therefor
US5464449A (en) * 1993-07-08 1995-11-07 Thomas J. Fogarty Internal graft prosthesis and delivery system
CA2125258C (en) * 1993-08-05 1998-12-22 Dinah B Quiachon Multicapsule intraluminal grafting system and method
US5941908A (en) * 1997-04-23 1999-08-24 Vascular Science, Inc. Artificial medical graft with a releasable retainer

Cited By (265)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040241768A1 (en) * 2000-05-08 2004-12-02 Whitten David G. Fluorescent polymer-QTL approach to biosensing
US8257427B2 (en) 2001-09-11 2012-09-04 J.W. Medical Systems, Ltd. Expandable stent
US8080048B2 (en) 2001-12-03 2011-12-20 Xtent, Inc. Stent delivery for bifurcated vessels
US8702781B2 (en) 2001-12-03 2014-04-22 J.W. Medical Systems Ltd. Apparatus and methods for delivery of multiple distributed stents
US20040249434A1 (en) * 2001-12-03 2004-12-09 Xtent, Inc. Stent delivery for bifuricated vessels
US7892273B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Custom length stent apparatus
US8016871B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US8016870B2 (en) 2001-12-03 2011-09-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US8070789B2 (en) 2001-12-03 2011-12-06 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US8956398B2 (en) 2001-12-03 2015-02-17 J.W. Medical Systems Ltd. Custom length stent apparatus
US8083788B2 (en) 2001-12-03 2011-12-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US8574282B2 (en) 2001-12-03 2013-11-05 J.W. Medical Systems Ltd. Apparatus and methods for delivery of braided prostheses
US7892274B2 (en) 2001-12-03 2011-02-22 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US8177831B2 (en) 2001-12-03 2012-05-15 Xtent, Inc. Stent delivery apparatus and method
US9326876B2 (en) 2001-12-03 2016-05-03 J.W. Medical Systems Ltd. Apparatus and methods for delivery of multiple distributed stents
US9901474B2 (en) 2002-12-02 2018-02-27 Gi Dynamics, Inc. Anti-obesity devices
US20050075622A1 (en) * 2002-12-02 2005-04-07 Gi Dynamics, Inc. Bariatric sleeve
US7935073B2 (en) 2002-12-02 2011-05-03 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
WO2004049982A3 (en) * 2002-12-02 2004-10-14 Gi Dynamics Inc Bariatric sleeve
US8486153B2 (en) 2002-12-02 2013-07-16 Gi Dynamics, Inc. Anti-obesity devices
US9750596B2 (en) 2002-12-02 2017-09-05 Gi Dynamics, Inc. Bariatric sleeve
US8882698B2 (en) 2002-12-02 2014-11-11 Gi Dynamics, Inc. Anti-obesity devices
US9278020B2 (en) 2002-12-02 2016-03-08 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US8870806B2 (en) 2002-12-02 2014-10-28 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US20050085923A1 (en) * 2002-12-02 2005-04-21 Gi Dynamics, Inc. Anti-obesity devices
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
US9155609B2 (en) 2002-12-02 2015-10-13 Gi Dynamics, Inc. Bariatric sleeve
US7766861B2 (en) 2002-12-02 2010-08-03 Gi Dynamics, Inc. Anti-obesity devices
US7758535B2 (en) 2002-12-02 2010-07-20 Gi Dynamics, Inc. Bariatric sleeve delivery devices
US8162871B2 (en) 2002-12-02 2012-04-24 Gi Dynamics, Inc. Bariatric sleeve
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US20040107004A1 (en) * 2002-12-02 2004-06-03 Seedling Enterprises, Llc Bariatric sleeve
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US8137301B2 (en) 2002-12-02 2012-03-20 Gi Dynamics, Inc. Bariatric sleeve
US8740968B2 (en) 2003-01-17 2014-06-03 J.W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US8282680B2 (en) 2003-01-17 2012-10-09 J. W. Medical Systems Ltd. Multiple independent nested stent structures and methods for their preparation and deployment
US20040220682A1 (en) * 2003-03-28 2004-11-04 Gi Dynamics, Inc. Anti-obesity devices
US9724217B2 (en) 2003-04-03 2017-08-08 Cook Medical Technologies Llc Branch stent graft deployment and method
US20090254170A1 (en) * 2003-04-03 2009-10-08 William A. Cook Australia Pty. Ltd. Branch stent graft deployment and method
US10413434B2 (en) 2003-04-03 2019-09-17 Cook Medical Technologies Llc Branch stent graft deployment and method
US8361134B2 (en) * 2003-04-03 2013-01-29 Cook Medical Technologies Llc Branch stent graft deployment and method
US7918881B2 (en) 2003-06-09 2011-04-05 Xtent, Inc. Stent deployment systems and methods
US20090276032A1 (en) * 2003-08-11 2009-11-05 Igor Waysbeyn Docking head for connecting vascular device to a vessel
US8361142B2 (en) 2003-08-11 2013-01-29 HDH Medical, Ltd. Docking head for connecting vascular device to a vessel
US8721710B2 (en) * 2003-08-11 2014-05-13 Hdh Medical Ltd. Anastomosis system and method
US8147501B2 (en) 2003-08-11 2012-04-03 Hdh Medical Ltd. Anastomosis method
US20090276035A1 (en) * 2003-08-11 2009-11-05 Igor Waysbeyn Anastomosis method
US20050038502A1 (en) * 2003-08-11 2005-02-17 Igor Waysbeyn Anastomosis system and method
US8062349B2 (en) 2003-09-03 2011-11-22 Bolton Medical, Inc. Method for aligning a stent graft delivery system
US11413173B2 (en) 2003-09-03 2022-08-16 Bolton Medical, Inc. Stent graft with a longitudinal support member
US20050049674A1 (en) * 2003-09-03 2005-03-03 Berra Humberto A. Stent graft
US9877857B2 (en) 2003-09-03 2018-01-30 Bolton Medical, Inc. Sheath capture device for stent graft delivery system and method for operating same
US9907686B2 (en) 2003-09-03 2018-03-06 Bolton Medical, Inc. System for implanting a prosthesis
US8740963B2 (en) 2003-09-03 2014-06-03 Bolton Medical, Inc. Methods of implanting a prosthesis and treating an aneurysm
US11813158B2 (en) 2003-09-03 2023-11-14 Bolton Medical, Inc. Stent graft delivery device
US9913743B2 (en) 2003-09-03 2018-03-13 Bolton Medical, Inc. Methods of implanting a prosthesis and treating an aneurysm
US8007605B2 (en) 2003-09-03 2011-08-30 Bolton Medical, Inc. Method of forming a non-circular stent
US11596537B2 (en) 2003-09-03 2023-03-07 Bolton Medical, Inc. Delivery system and method for self-centering a proximal end of a stent graft
US9173755B2 (en) 2003-09-03 2015-11-03 Bolton Medical, Inc. Vascular repair devices
US9198786B2 (en) 2003-09-03 2015-12-01 Bolton Medical, Inc. Lumen repair device with capture structure
US8062345B2 (en) 2003-09-03 2011-11-22 Bolton Medical, Inc. Delivery systems for delivering and deploying stent grafts
US9925080B2 (en) 2003-09-03 2018-03-27 Bolton Medical, Inc. Methods of implanting a prosthesis
US9220617B2 (en) 2003-09-03 2015-12-29 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US8636788B2 (en) 2003-09-03 2014-01-28 Bolton Medical, Inc. Methods of implanting a prosthesis
US8070790B2 (en) 2003-09-03 2011-12-06 Bolton Medical, Inc. Capture device for stent graft delivery
US9320631B2 (en) 2003-09-03 2016-04-26 Bolton Medical, Inc. Aligning device for stent graft delivery system
US10105250B2 (en) 2003-09-03 2018-10-23 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US9655712B2 (en) 2003-09-03 2017-05-23 Bolton Medical, Inc. Vascular repair devices
US11259945B2 (en) 2003-09-03 2022-03-01 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US10182930B2 (en) 2003-09-03 2019-01-22 Bolton Medical, Inc. Aligning device for stent graft delivery system
US11103341B2 (en) 2003-09-03 2021-08-31 Bolton Medical, Inc. Stent graft delivery device
US9333104B2 (en) 2003-09-03 2016-05-10 Bolton Medical, Inc. Delivery systems for delivering and deploying stent grafts
US8500792B2 (en) 2003-09-03 2013-08-06 Bolton Medical, Inc. Dual capture device for stent graft delivery system and method for capturing a stent graft
US10213291B2 (en) 2003-09-03 2019-02-26 Bolto Medical, Inc. Vascular repair devices
US10390929B2 (en) 2003-09-03 2019-08-27 Bolton Medical, Inc. Methods of self-aligning stent grafts
US9408734B2 (en) 2003-09-03 2016-08-09 Bolton Medical, Inc. Methods of implanting a prosthesis
US9408735B2 (en) 2003-09-03 2016-08-09 Bolton Medical, Inc. Methods of implanting a prosthesis and treating an aneurysm
US10945827B2 (en) 2003-09-03 2021-03-16 Bolton Medical, Inc. Vascular repair devices
US8449595B2 (en) 2003-09-03 2013-05-28 Bolton Medical, Inc. Delivery systems for delivering and deploying stent grafts
US8292943B2 (en) 2003-09-03 2012-10-23 Bolton Medical, Inc. Stent graft with longitudinal support member
US9561124B2 (en) 2003-09-03 2017-02-07 Bolton Medical, Inc. Methods of self-aligning stent grafts
US8308790B2 (en) 2003-09-03 2012-11-13 Bolton Medical, Inc. Two-part expanding stent graft delivery system
US10918509B2 (en) 2003-09-03 2021-02-16 Bolton Medical, Inc. Aligning device for stent graft delivery system
US10646365B2 (en) 2003-09-03 2020-05-12 Bolton Medical, Inc. Delivery system and method for self-centering a proximal end of a stent graft
WO2005034811A1 (en) * 2003-10-10 2005-04-21 William Cook Europe Aps Stent graft retention system
US7575591B2 (en) 2003-12-01 2009-08-18 Cordis Corporation Prosthesis graft with Z pleating
EP1537836A3 (en) * 2003-12-01 2007-10-03 Cordis Corporation Prosthesis graft with z pleating
US9095416B2 (en) 2003-12-09 2015-08-04 Gi Dynamics, Inc. Removal and repositioning devices
US9084669B2 (en) 2003-12-09 2015-07-21 Gi Dynamics, Inc. Methods and apparatus for anchoring within the gastrointestinal tract
US8834405B2 (en) 2003-12-09 2014-09-16 Gi Dynamics, Inc. Intestinal sleeve
US8057420B2 (en) 2003-12-09 2011-11-15 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
US20050125075A1 (en) * 2003-12-09 2005-06-09 Gi Dynamics, Inc. Intestinal sleeve
US8771219B2 (en) 2003-12-09 2014-07-08 Gi Dynamics, Inc. Gastrointestinal implant with drawstring
US9585783B2 (en) 2003-12-09 2017-03-07 Gi Dynamics, Inc. Methods and apparatus for anchoring within the gastrointestinal tract
US7981163B2 (en) 2003-12-09 2011-07-19 Gi Dynamics, Inc. Intestinal sleeve
US9744061B2 (en) 2003-12-09 2017-08-29 Gi Dynamics, Inc. Intestinal sleeve
US8303669B2 (en) 2003-12-09 2012-11-06 Gi Dynamics, Inc. Methods and apparatus for anchoring within the gastrointestinal tract
US8628583B2 (en) 2003-12-09 2014-01-14 Gi Dynamics, Inc. Methods and apparatus for anchoring within the gastrointestinal tract
US7682330B2 (en) 2003-12-09 2010-03-23 Gi Dynamics, Inc. Intestinal sleeve
US9237944B2 (en) 2003-12-09 2016-01-19 Gi Dynamics, Inc. Intestinal sleeve
US7815589B2 (en) 2003-12-09 2010-10-19 Gi Dynamics, Inc. Methods and apparatus for anchoring within the gastrointestinal tract
US9566179B2 (en) 2003-12-23 2017-02-14 J.W. Medical Systems Ltd. Devices and methods for controlling and indicating the length of an interventional element
US8585747B2 (en) 2003-12-23 2013-11-19 J.W. Medical Systems Ltd. Devices and methods for controlling and indicating the length of an interventional element
US8460358B2 (en) 2004-03-30 2013-06-11 J.W. Medical Systems, Ltd. Rapid exchange interventional devices and methods
US9700448B2 (en) 2004-06-28 2017-07-11 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8986362B2 (en) 2004-06-28 2015-03-24 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US8317859B2 (en) 2004-06-28 2012-11-27 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US7837643B2 (en) 2004-07-09 2010-11-23 Gi Dynamics, Inc. Methods and devices for placing a gastrointestinal sleeve
WO2006016894A1 (en) * 2004-07-09 2006-02-16 Gi Dynamics, Inc. Methods and devices for placing a gastrointestinal sleeve
US9572654B2 (en) 2004-08-31 2017-02-21 C.R. Bard, Inc. Self-sealing PTFE graft with kink resistance
US10582997B2 (en) 2004-08-31 2020-03-10 C. R. Bard, Inc. Self-sealing PTFE graft with kink resistance
US8313524B2 (en) 2004-08-31 2012-11-20 C. R. Bard, Inc. Self-sealing PTFE graft with kink resistance
US7815591B2 (en) 2004-09-17 2010-10-19 Gi Dynamics, Inc. Atraumatic gastrointestinal anchor
US8920358B2 (en) 2005-01-19 2014-12-30 Gi Dynamics, Inc. Resistive anti-obesity devices
US8096966B2 (en) 2005-01-19 2012-01-17 Gi Dynamics, Inc. Eversion resistant sleeves
US7771382B2 (en) 2005-01-19 2010-08-10 Gi Dynamics, Inc. Resistive anti-obesity devices
US20100298632A1 (en) * 2005-01-19 2010-11-25 Gi Dynamics, Inc. Resistive Anti-Obesity Devices
US7766973B2 (en) 2005-01-19 2010-08-03 Gi Dynamics, Inc. Eversion resistant sleeves
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US8226710B2 (en) 2005-05-13 2012-07-24 Medtronic Corevalve, Inc. Heart valve prosthesis and methods of manufacture and use
US9056000B2 (en) * 2005-05-24 2015-06-16 Microport Endovascular (Shanghai) Co., Ltd. Flexible stent-graft
US20080195191A1 (en) * 2005-05-24 2008-08-14 Qiyi Luo Flexible Stent-Graft
US7976488B2 (en) 2005-06-08 2011-07-12 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US8425451B2 (en) 2005-06-08 2013-04-23 Gi Dynamics, Inc. Gastrointestinal anchor compliance
US8652284B2 (en) 2005-06-17 2014-02-18 C. R. Bard, Inc. Vascular graft with kink resistance after clamping
US8066758B2 (en) * 2005-06-17 2011-11-29 C. R. Bard, Inc. Vascular graft with kink resistance after clamping
US20100179642A1 (en) * 2005-06-17 2010-07-15 C.R. Bard, Inc. Vascular Graft With Kink Resistance After Clamping
US8202311B2 (en) 2005-07-27 2012-06-19 Cook Medical Technologies Llc Stent/graft device and method for open surgical placement
US8821565B2 (en) 2005-07-27 2014-09-02 Cook Medical Technologies Llc Stent/graft device for open surgical placement
US20070027526A1 (en) * 2005-07-27 2007-02-01 Cook Critical Care Incorporated Stent/graft device and method for open surgical placement
US8636794B2 (en) 2005-11-09 2014-01-28 C. R. Bard, Inc. Grafts and stent grafts having a radiopaque marker
US9155491B2 (en) 2005-11-09 2015-10-13 C.R. Bard, Inc. Grafts and stent grafts having a radiopaque marker
US8652198B2 (en) 2006-03-20 2014-02-18 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US9883957B2 (en) 2006-03-20 2018-02-06 J.W. Medical Systems Ltd. Apparatus and methods for deployment of linked prosthetic segments
US7819836B2 (en) 2006-06-23 2010-10-26 Gi Dynamics, Inc. Resistive anti-obesity devices
DE102006033399A1 (en) * 2006-07-19 2008-01-24 Jotec Gmbh X-ray marker for precise implantation of stents
US20080051870A1 (en) * 2006-07-19 2008-02-28 Ralf Kaufmann Marker element for the precise implantation of stents
DE102006033399B4 (en) * 2006-07-19 2009-04-09 Jotec Gmbh Marker system and delivery system for such a marker system
US8002820B2 (en) 2006-07-19 2011-08-23 Jotec Gmbh Marker element for the precise implantation of stents
US9198749B2 (en) 2006-10-12 2015-12-01 C. R. Bard, Inc. Vascular grafts with multiple channels and methods for making
KR101431776B1 (en) 2006-10-16 2014-08-20 롬바드 메디컬 리미티드 System and method for positioning a stent graft
US20110125252A1 (en) * 2006-10-16 2011-05-26 Robert William Goddard System and method for positioning a stent graft
WO2008047092A1 (en) * 2006-10-16 2008-04-24 Anson Medical Ltd System and method for positioning a stent graft
US8979919B2 (en) 2006-10-16 2015-03-17 Anson Medical Limited System and method for positioning a stent graft
US8980297B2 (en) 2007-02-20 2015-03-17 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US9457133B2 (en) 2007-02-20 2016-10-04 J.W. Medical Systems Ltd. Thermo-mechanically controlled implants and methods of use
US8801647B2 (en) 2007-02-22 2014-08-12 Gi Dynamics, Inc. Use of a gastrointestinal sleeve to treat bariatric surgery fistulas and leaks
US8486132B2 (en) 2007-03-22 2013-07-16 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US9339404B2 (en) 2007-03-22 2016-05-17 J.W. Medical Systems Ltd. Devices and methods for controlling expandable prostheses during deployment
US20090030497A1 (en) * 2007-07-25 2009-01-29 Metcalf Justin M Retention Wire For Self-Expanding Stent
US8092510B2 (en) * 2007-07-25 2012-01-10 Cook Medical Technologies Llc Retention wire for self-expanding stent
WO2009038949A1 (en) * 2007-09-19 2009-03-26 Xtent, Inc. Apparatus and methods for deployment of multiple custom-length prostheses
US20090112237A1 (en) * 2007-10-26 2009-04-30 Cook Critical Care Incorporated Vascular conduit and delivery system for open surgical placement
US8506583B2 (en) 2007-10-26 2013-08-13 Cook Medical Technologies Llc Method for open surgical placement
US20090171442A1 (en) * 2007-12-27 2009-07-02 Cook Incorporated Z-stent with incorporated barbs
US7905915B2 (en) 2007-12-27 2011-03-15 Cook Incorporated Z-stent with incorporated barbs
US20100286794A1 (en) * 2008-01-10 2010-11-11 Novatech Sa Endoprosthesis for anatomical duct
US11083573B2 (en) 2008-01-24 2021-08-10 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US10646335B2 (en) 2008-01-24 2020-05-12 Medtronic, Inc. Stents for prosthetic heart valves
US11786367B2 (en) 2008-01-24 2023-10-17 Medtronic, Inc. Stents for prosthetic heart valves
US11607311B2 (en) 2008-01-24 2023-03-21 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US11284999B2 (en) 2008-01-24 2022-03-29 Medtronic, Inc. Stents for prosthetic heart valves
US10758343B2 (en) 2008-01-24 2020-09-01 Medtronic, Inc. Stent for prosthetic heart valves
US10820993B2 (en) 2008-01-24 2020-11-03 Medtronic, Inc. Stents for prosthetic heart valves
US11259919B2 (en) 2008-01-24 2022-03-01 Medtronic, Inc. Stents for prosthetic heart valves
US10016274B2 (en) 2008-01-24 2018-07-10 Medtronic, Inc. Stent for prosthetic heart valves
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US8685077B2 (en) 2008-01-24 2014-04-01 Medtronics, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8157852B2 (en) * 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9149358B2 (en) * 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US8157853B2 (en) * 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9101503B2 (en) 2008-03-06 2015-08-11 J.W. Medical Systems Ltd. Apparatus having variable strut length and methods of use
US7655037B2 (en) * 2008-04-17 2010-02-02 Cordis Corporation Combination barb restraint and stent attachment deployment mechanism
AU2009201472B2 (en) * 2008-04-17 2014-06-26 Cardinal Health 529, Llc Combination barb restraint and stent attachment deployment mechanism
US20090264992A1 (en) * 2008-04-17 2009-10-22 Fleming Iii James A Combination barb restraint and stent attachment deployment mechanism
US10307275B2 (en) 2008-06-30 2019-06-04 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US10105248B2 (en) 2008-06-30 2018-10-23 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US10864097B2 (en) 2008-06-30 2020-12-15 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US11382779B2 (en) 2008-06-30 2022-07-12 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US9364314B2 (en) 2008-06-30 2016-06-14 Bolton Medical, Inc. Abdominal aortic aneurysms: systems and methods of use
US8858617B2 (en) * 2008-08-29 2014-10-14 Cook Medical Technologies Llc Barbed anchors for wire stent
US20130190858A1 (en) * 2008-08-29 2013-07-25 Cook Medical Technologies Llc Barbed anchors for wire stent
US8579959B2 (en) * 2008-09-12 2013-11-12 Cook Medical Technologies Llc Radiopaque reinforcing member
US20110190868A1 (en) * 2008-09-12 2011-08-04 Werner Dieter Ducke Radiopaque reinforcing member
US10918506B2 (en) 2008-09-25 2021-02-16 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation
US9730821B2 (en) 2008-09-25 2017-08-15 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US9855158B2 (en) 2008-09-25 2018-01-02 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US11857442B2 (en) 2008-09-25 2024-01-02 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation
US11839562B2 (en) 2008-09-25 2023-12-12 Advanced Bifurcation Systems Inc. Partially crimped stent
US9737424B2 (en) 2008-09-25 2017-08-22 Advanced Bifurcation Systems, Inc. Partially crimped stent
US8828071B2 (en) 2008-09-25 2014-09-09 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US8821562B2 (en) 2008-09-25 2014-09-02 Advanced Bifurcation Systems, Inc. Partially crimped stent
US11426297B2 (en) 2008-09-25 2022-08-30 Advanced Bifurcation Systems Inc. Selective stent crimping
US8769796B2 (en) 2008-09-25 2014-07-08 Advanced Bifurcation Systems, Inc. Selective stent crimping
US8979917B2 (en) 2008-09-25 2015-03-17 Advanced Bifurcation Systems, Inc. System and methods for treating a bifurcation
US10610391B2 (en) 2008-09-25 2020-04-07 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US9724218B2 (en) 2008-09-25 2017-08-08 Advanced Bifurcation Systems, Inc. Methods and systems for ostial stenting of a bifurcation
US11298252B2 (en) 2008-09-25 2022-04-12 Advanced Bifurcation Systems Inc. Stent alignment during treatment of a bifurcation
US8808347B2 (en) 2008-09-25 2014-08-19 Advanced Bifurcation Systems, Inc. Stent alignment during treatment of a bifurcation
US11000392B2 (en) 2008-09-25 2021-05-11 Advanced Bifurcation Systems Inc. Partially crimped stent
US10219926B2 (en) 2008-09-25 2019-03-05 Advanced Bifurcation Systems Inc. Selective stent crimping
US10219927B2 (en) 2008-09-25 2019-03-05 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation
US8795347B2 (en) 2008-09-25 2014-08-05 Advanced Bifurcation Systems, Inc. Methods and systems for treating a bifurcation with provisional side branch stenting
US20100161605A1 (en) * 2008-12-23 2010-06-24 Yahoo! Inc. Context transfer in search advertising
CH700476A1 (en) * 2009-02-23 2010-08-31 Carag Ag Feeding system for feeding or introducing article, particularly stent, into body volume or hollow space, has outer sleeve that is concentrically provided around guiding wire
US9101506B2 (en) 2009-03-13 2015-08-11 Bolton Medical, Inc. System and method for deploying an endoluminal prosthesis at a surgical site
US10898357B2 (en) 2009-03-13 2021-01-26 Bolton Medical, Inc. System for deploying an endoluminal prosthesis at a surgical site
US9827123B2 (en) 2009-03-13 2017-11-28 Bolton Medical, Inc. System for deploying an endoluminal prosthesis at a surgical site
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US11351050B2 (en) 2010-06-13 2022-06-07 Synerz Medical, Inc. Intragastric device for treating obesity
US11135078B2 (en) 2010-06-13 2021-10-05 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US11607329B2 (en) 2010-06-13 2023-03-21 Synerz Medical, Inc. Intragastric device for treating obesity
US10512557B2 (en) 2010-06-13 2019-12-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US11596538B2 (en) 2010-06-13 2023-03-07 Synerz Medical, Inc. Intragastric device for treating obesity
US10413436B2 (en) 2010-06-13 2019-09-17 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US9017351B2 (en) 2010-06-29 2015-04-28 Artventive Medical Group, Inc. Reducing flow through a tubular structure
US9451965B2 (en) 2010-06-29 2016-09-27 Artventive Medical Group, Inc. Reducing flow through a tubular structure
US9247942B2 (en) 2010-06-29 2016-02-02 Artventive Medical Group, Inc. Reversible tubal contraceptive device
US9149277B2 (en) 2010-10-18 2015-10-06 Artventive Medical Group, Inc. Expandable device delivery
US11000393B2 (en) 2011-02-08 2021-05-11 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation with a fully crimped stent
US9364356B2 (en) 2011-02-08 2016-06-14 Advanced Bifurcation System, Inc. System and methods for treating a bifurcation with a fully crimped stent
US9254210B2 (en) 2011-02-08 2016-02-09 Advanced Bifurcation Systems, Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US11484424B2 (en) 2011-02-08 2022-11-01 Advanced Bifurcation Systems Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US11717428B2 (en) 2011-02-08 2023-08-08 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation with a fully crimped stent
US10285832B2 (en) 2011-02-08 2019-05-14 Advanced Bifurcation Systems Inc. System and methods for treating a bifurcation with a fully crimped stent
US10406010B2 (en) 2011-02-08 2019-09-10 Advanced Bifurcation Systems Inc. Multi-stent and multi-balloon apparatus for treating bifurcations and methods of use
US10993803B2 (en) 2011-04-01 2021-05-04 W. L. Gore & Associates, Inc. Elastomeric leaflet for prosthetic heart valves
US11457925B2 (en) 2011-09-16 2022-10-04 W. L. Gore & Associates, Inc. Occlusive devices
US11324615B2 (en) 2011-11-14 2022-05-10 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11382781B2 (en) 2011-11-14 2022-07-12 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US11123174B2 (en) 2012-03-13 2021-09-21 W. L. Gore & Associates, Inc. External steerable fiber for use in endoluminal deployment of expandable devices
US9554929B2 (en) 2012-04-12 2017-01-31 Bolton Medical, Inc. Vascular prosthetic delivery device and method of use
US8998970B2 (en) 2012-04-12 2015-04-07 Bolton Medical, Inc. Vascular prosthetic delivery device and method of use
US10299951B2 (en) 2012-04-12 2019-05-28 Bolton Medical, Inc. Vascular prosthetic delivery device and method of use
US11351049B2 (en) 2012-04-12 2022-06-07 Bolton Medical, Inc. Vascular prosthetic delivery device and method of use
US20140052232A1 (en) * 2012-08-10 2014-02-20 Altura Medical, Inc. Handle assemblies for stent graft delivery systems and associated systems and methods
US9795479B2 (en) * 2012-12-27 2017-10-24 Venus Medtech (Hangzhou), Inc. Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism, implant and method
US20150335426A1 (en) * 2012-12-27 2015-11-26 Transcatheter Technologies Gmbh Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism, implant and method
US9095344B2 (en) 2013-02-05 2015-08-04 Artventive Medical Group, Inc. Methods and apparatuses for blood vessel occlusion
US9737307B2 (en) 2013-02-05 2017-08-22 Artventive Medical Group, Inc. Blood vessel occlusion
US9107669B2 (en) 2013-02-05 2015-08-18 Artventive Medical Group, Inc. Blood vessel occlusion
US10004513B2 (en) 2013-02-05 2018-06-26 Artventive Medical Group, Inc. Bodily lumen occlusion
US8984733B2 (en) 2013-02-05 2015-03-24 Artventive Medical Group, Inc. Bodily lumen occlusion
US10555826B2 (en) 2013-03-15 2020-02-11 Bolton Medical, Inc. Hemostasis valve and delivery systems
US9827121B2 (en) 2013-03-15 2017-11-28 Cook Medical Technologies Llc Quick release deployment handle for medical devices
US11666467B2 (en) 2013-03-15 2023-06-06 Bolton Medical, Inc. Hemostasis valve and delivery systems
US9439751B2 (en) 2013-03-15 2016-09-13 Bolton Medical, Inc. Hemostasis valve and delivery systems
US10441290B2 (en) 2013-06-14 2019-10-15 Artventive Medical Group, Inc. Implantable luminal devices
US9636116B2 (en) 2013-06-14 2017-05-02 Artventive Medical Group, Inc. Implantable luminal devices
US9737308B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US9737306B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Implantable luminal devices
US10149968B2 (en) 2013-06-14 2018-12-11 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US10363043B2 (en) 2014-05-01 2019-07-30 Artventive Medical Group, Inc. Treatment of incompetent vessels
US11224438B2 (en) 2014-05-01 2022-01-18 Artventive Medical Group, Inc. Treatment of incompetent vessels
CN106456150A (en) * 2014-06-16 2017-02-22 库克医药技术有限责任公司 Plunger-driven collet handle and system for fiducial deployment
US11129622B2 (en) 2015-05-14 2021-09-28 W. L. Gore & Associates, Inc. Devices and methods for occlusion of an atrial appendage
US10813644B2 (en) 2016-04-01 2020-10-27 Artventive Medical Group, Inc. Occlusive implant and delivery system
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US11173023B2 (en) 2017-10-16 2021-11-16 W. L. Gore & Associates, Inc. Medical devices and anchors therefor
US11589943B2 (en) * 2017-12-20 2023-02-28 Koninklijke Philips N.V. Torsional deployment detection of a vascular therapy
CN111741728A (en) * 2017-12-20 2020-10-02 皇家飞利浦有限公司 Torsional deployment detection of vascular treatment devices
US20210085421A1 (en) * 2017-12-20 2021-03-25 Koninklijke Philips N.V. Torsional deployment detection of a vascular therapy
WO2019121889A1 (en) * 2017-12-20 2019-06-27 Koninklijke Philips N.V. Torsional deployment detection of a vascular therapy device

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US6346118B1 (en) 2002-02-12
AU4684796A (en) 1996-07-03
US5693083A (en) 1997-12-02
EP0797415A1 (en) 1997-10-01
JP2002503114A (en) 2002-01-29
WO1996018361A1 (en) 1996-06-20
CA2207596A1 (en) 1996-06-20
AU704204B2 (en) 1999-04-15

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