US20020156400A1 - Ultrasonic method and device for wound treatment - Google Patents
Ultrasonic method and device for wound treatment Download PDFInfo
- Publication number
- US20020156400A1 US20020156400A1 US09/840,416 US84041601A US2002156400A1 US 20020156400 A1 US20020156400 A1 US 20020156400A1 US 84041601 A US84041601 A US 84041601A US 2002156400 A1 US2002156400 A1 US 2002156400A1
- Authority
- US
- United States
- Prior art keywords
- ultrasound
- liquid
- tip
- wound
- ultrasonic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0623—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn
- B05B17/063—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn having an internal channel for supplying the liquid or other fluent material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/30—Gas therapy for therapeutic treatment of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0623—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers coupled with a vibrating horn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
- A61M2205/058—General characteristics of the apparatus combined with other kinds of therapy with ultrasound therapy
Abstract
Description
- The present invention relates to a method of using ultrasonic waves in wound treatment. In particular, the present invention relates to a method of spraying a wound surface using ultrasonic waves for delivering drugs, killing bacteria, cleansing a surface, increasing blood flow and stimulating healthy tissue cells.
- Ultrasonic waves have been widely used in medical applications, including both diagnostics and therapy, as well as in many industrial applications. One diagnostic use of ultrasound waves includes using ultrasonic waves to detect underlying structures in an object or human tissue. In this method, an ultrasonic transducer is placed in contact with the tissue (or object) via a coupling medium, and high frequency (1-10 MHz) ultrasonic waves are directed into the tissue. Upon contact with underlying structures, the waves are reflected back to a receiver adjacent the transducer. By comparison of the signals of an ultrasonic wave as sent with the reflected ultrasonic wave as received, an image of the underlying structure can be produced. This technique is particularly useful for identifying boundaries between components of tissue and can be used to detect irregular masses, tumors, and the like.
- Two therapeutic medical uses of ultrasonic waves include aerosol mist production and contact physiotherapy. Aerosol mist production makes use of a nebulizer or inhaler to produce an aerosol mist for creating a humid environment and delivering drug to the lung.
- Ultrasonic nebulizers operate by passing ultrasonic waves of sufficient intensity through a liquid, the waves being directed at an air-liquid interface of the liquid from a point underneath or within the liquid. Liquid particles are ejected from the surface of the liquid into the surrounding air following the disintegration of capillary waves produced by the ultrasound. This technique can produce a very fine dense fog or mist. Aerosol mists produced by ultrasound are preferred because a smaller particle size of the aerosol can be obtained with the ultrasonic waves. One of the major shortcomings of inhalers and nebulizers is that there are no directed aerosol to the target without an air stream, which decreases the efficiency of ultrasound.
- Contact physiotherapy applies ultrasonic waves directly to tissue in an attempt to produce a physical change in the tissue. In conventional ultrasound physiotherapy, an ultrasonic transducer contacts the tissue via a coupling medium. Ultrasonic waves produced by the transducer travel through the coupling medium and into the tissue. The coupling medium is typically a bath of liquid, a jelly applied to the surface to be treated, or a water-filled balloon. Conventional techniques provide ultrasonic waves having an intensity of from about 0.25 w/cm2 to 3 w/cm2 at a frequency of from about 0.8 to 3 Megahertz. The treatment is applied to a skin surface for from about 1 to 30 minutes, two or three times a week. The coupling medium can provide a cooling effect which dissipates some of the heat energy produced by the ultrasonic transducer. More importantly, a coupling medium or direct contact between the tissue and the ultrasonic transducer is necessary to transmit the ultrasonic waves from the transducer to the skin surface because ambient air is a relatively poor medium for the propagation of ultrasonic waves.
- Several beneficial effects have been reported from contact ultrasound physiotherapy. For example, the following effects have been associated with contact ultrasound physiotherapy: local improvement of the blood circulation, heating of the tissue, accelerated enzyme activity, muscle relaxation, pain reduction, and enhancement of natural healing processes. Despite these beneficial effects, current techniques of medical physiotherapy using ultrasonic waves are limited by the necessity of providing a direct contact interface between the ultrasonic transducer and the tissue to maintain an effective transmission of the ultrasonic waves from the transducer to the tissue. The necessity of direct contact with or without a coupling medium makes current methods undesirable. Some tissue conditions may be accessible to contact ultrasound devices but would be impractical for contact ultrasound treatment. For example, fresh or open wounds resulting from trauma, bums, surgical interventions are not suitable for direct contact ultrasound treatment because of the structural of the structural nature of the open wound and the painful condition associated with those wounds. Moreover, conventional contact ultrasound may have a destructive effect on these types of open wounds due to the close proximity of an oscillating tip of an ultrasonic transducer relative to the already damaged tissue surface.
- It is an object of the invention to provide a method and device for treating wounds.
- It is also an object of this invention to provide a method and device for treating wounds using ultrasonic waves.
- It is another object of the invention to provide a method and device for delivering drugs and irrigation to wounds.
- It is a yet another object of the invention to provide a method and device for the mechanical cleansing and debridement of wounds.
- It is a further object of the invention to provide a method and device for increasing blood flow in a wound area.
- It is a yet further object of the invention to treat a wound by spraying the surface of the wound with an aerosol mist produced by ultrasonic waves.
- These and other objects of the invention will become more apparent from the discussion below.
- The present invention concerns a method and device for spraying a wound surface to deliver drugs, kill bacteria, or cleanse a surface by non-contact application of ultrasonic waves. The ultrasonic waves are applied to the wound without requiring direct or indirect (via a traditional coupling medium) contact between an ultrasonic wave transducer and the wound to be sprayed.
- Ultrasonic sprayers (Sonic and Materials Inc., Misonix Inc., Sono-Tek Inc.; U.S. Pat. Nos. 4,153,201, 4,655,393, and 5,516,043) typically operate by passing liquid through the central orifice of the tip of an ultrasound instrument. Known applications are essentially industrial, such as a burner or device for coating of surfaces. No ultrasound wound or biological tissue treatment application with such a device has been indicated, with the exception of ultrasound liposuction.
- According to the present invention a directed spray of liquid particles produced by contact of the liquid with a free end surface of an ultrasonic transducer is directed onto a wound. The ultrasonic waves cause the spray to project outwardly from the distal end surface, and the particles of the spray provide a medium for propagation of the ultrasonic waves emanating from the distal end surface.
- In the method of the present invention, particle spray created by low frequency ultrasound waves and directed at the surface of a wound, can deliver drugs, kill bacteria on the wound, increase blood flow, and/or remove dirt and other contaminants from that surface (mechanical cleansing). This method of drug delivery is particularly advantageous on tissues for which local topical application of a drug is desirable yet contact with the tissue is to be avoided. Furthermore, the low frequency ultrasound waves used in the method energize the drug and cause penetration of the drug below the surface of the tissue. Finally, the bacteria killing method is effective when applied to the surface whether the liquid sprayed is a drug (an antiseptic or antibiotic), oil, saline, distilled water, or the like.
- In a device acording to the invention, a spray is produced by first delivering liquid to the free distal end surface of an ultrasound tip through the axial (center) orifice or hose. After liquid is delivered to the free distal end surface, ultrasonic waves create the spray, which is directed to a particular targeted surface such a wound. Simultaneously ultrasonic waves are delivered to the wound surface through the spray.
- The device must have a nozzle made from a rigid material such as steel (non-disposable) or plastic (disposable). The nozzle allows liquid to be delivered to a lateral surface of the transducer tip or directly to the distal side (radiation surface) of the ultrasound instrument to be sprayed.
- FIG. 1 is a perspective view of an ultrasonic wound treatment system for use according to the invention;
- FIG. 2 is a partial cross-sectional view of the distal portion of an ultrasonic wound treatment device of the invention with a central orifice;
- FIG. 3 is a partial cross-sectional view of the distal portion of an ultrasonic wound treatment device of the invention with no central orifice;
- FIG. 4 is a partial cross-sectional view of the distal portion of an ultrasonic wound treatment device of the invention with focused ultrasound;
- FIG. 5 is a partial cross-sectional view of the distal portion of an ultrasonic wound treatment device of the invention with a thread on a radial surface;
- FIG. 6 is a partial cross-sectional view of the distal portion of an ultrasonic wound treatment device of the invention with a thread in a central orifice;
- FIG. 7 is a partial cross-sectional view of the distal portion of a device for spraying where fluid is delivered to a lateral or radiation surface of the transducer tip by tube or sleeve and gas is delivered through the ultrasound tip's central orifice;
- FIG. 8 is a partial cross-sectional view of the distal portion of a device for spraying where gas is delivered to a lateral or radiation surface of the transducer tip the through housing or bushing by perimeter of the tip and liquid is delivered through the ultrasound tip's central orifice;
- FIG. 9 is a view illustrating use of a bushing for better effect of ultrasound standing waves to treat wounds; and
- FIG. 10 is a partial cross-sectional view of a nozzle for ultrasound wound treatment using two tubes, one for carrying gas such a oxygen and another for carrying liquid such as a therapeutic agent.
- The present invention is a method and device, which uses ultrasonic wave energy to treat wounds. The device comprises a generator of electrical signals and a handpiece having an ultrasound transducer tip. The handpiece also comprises a tube for delivering drug to the radiation surface of the ultrasound tip.
- The invention can perhaps be better appreciated from the drawings. In FIG. 1, a
system 10 according to the invention comprises anultrasound generator 12 in operative connection throughcable 14 with anultrasound handpiece 16.Handpiece 16 comprises anultrasound nozzle 18 and a transducer 20 and is in fluid communication through connectingmember 22 withliquid reservoir 24. Liquid dispensed fromreservoir 24 contacts the distal end orradiation surface 26 ofnozzle 18, resulting in aspray 30 that is directed toward thesurface 32 ofwound 34. In this fashion liquid is sprayed on the wound surface while ultrasonic waves are delivered to the wound. - FIG. 2 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 36 for wound treatment with a central lumen ororifice 38, as used in a device of the present invention. Liquid from a reservoir (not shown) is delivered in the direction of arrow 40 to thedistal end 42 ofultrasound tip 36 throughcentral orifice 38 to createultrasound mist 44, which is directed to thesurface 46 of awound 48. - FIG. 3 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 50 for wound treatment with no central orifice, as used in a device of the present invention. Liquid from a reservoir (not shown) is delivered in the direction ofarrow 52 to a soliddistal end 54 ofultrasound tip 50 through alumen 55 intubing 56, to createultrasound mist 58.Ultrasound mist 58 is directed to thesurface 60 of awound 62. - FIG. 4 is a schematic representation of a cross-section of an ultrasonic nozzle tip66 with focused energy for wound treatment with no central orifice, as used according to the invention. Liquid 68 from a reservoir (not shown) is delivered in the direction of arrow 68 to the solid
distal end 70 of ultrasound tip 66 through a lumen 71 intubing 72 to create anultrasound mist 74 that is directed to afocal point 76 on thesurface 78 of a wound 80. Ultrasound tipdistal end 70 is curved, e.g., elliptical, oval, etc. - FIG. 5 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 84 for wound treatment withgrooves 86 on aradial surface 88. Liquid from a reservoir (not shown) is delivered in the direction of arrow 90 toradial surface 88 through a lumen 91 intubing 92, to create anultrasound mist 94.Ultrasound mist 94 is directed to thesurface 96 of awound 98.Grooves 86 can alternatively be threads or rings. - FIG. 6 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 102 for wound treatment withthread 104 in a central lumen ororifice 106. Liquid from a reservoir (not shown) is delivered in the direction of arrow 108 throughcentral orifice 106 to the distal end 110 ofultrasound tip 102 to create an ultrasound mist 112. Ultrasound mist 112 is directed to thesurface 114 of a wound 116. - FIG. 7 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 120 for wound treatment with a central lumen ororifice 122. Liquid from a reservoir (not shown) is delivered in the direction of arrow 124 through alumen 128 intubing 130 to the distal end 132 ofultrasound tip 120 to create an ultrasound mist 134. A gas such as oxygen is delivered in the direction ofarrow 136 throughcentral orifice 122. Ultrasound mist 134 is directed to thesurface 138 ofwound 140. Alternatively, liquid can be delivered in the direction ofarrow 136 throughcentral orifice 122 and gas can be delivered in the direction of arrow 124 throughlumen 128. - FIG. 8 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 146 for wound treatment with a central lumen ororifice 148. Liquid from a reservoir (not shown) is delivered to the distal end 152 ofultrasound tip 146 throughcentral orifice 148, to create anultrasound mist 154.Ultrasound mist 154 also carries a gas such as oxygen, delivered in the direction of arrow 156 throughannular channel 158 formed bybushing 160.Ultrasound mist 154 contacts the surface 164 of wound 166. Alternatively, gas liquid can be delivered in the direction of arrow 156 throughannular channel 158 and gas can be delivered in the direction of arrow 150 throughcentral orifice 148. - FIG. 9 is a schematic representation of a cross-section of an
ultrasonic nozzle tip 168 for wound treatment with a central lumen ororifice 170 and an expandedbushing 176, which creates better conditions for standing waves. Liquid from a reservoir (not shown) is delivered in the direction of arrow 172. Substantially annular channel 174 is formed by expendedbushing 176, and gas such as oxygen is delivered through annular channel 174 in the direction of arrow 178. An ultrasound mist 180 created at the distal end 182 ofultrasound tip 168 is directed at the surface 184 of wound 186. Alternatively, liquid can be delivered in the direction of arrow 178 through annular channel 174 and gas can be delivered in the direction of arrow 172 throughcentral orifice 170. - FIG. 10 is a schematic representation of an
ultrasonic nozzle tip 190 with no central orifice, where liquid is delivered from a reservoir (not shown) in the direction of arrow 192 through a lumen 194 intubing 196 to the distal end 198 oftip 190. A gas such as oxygen is delivered from a gas source (not shown) in the direction of arrow 200 through alumen 202 intubing 204 to tip distal end 198. Anultrasound mist 206 created at tip distal end 198 is directed to the surface 208 of wound 216. - The cross-section of the ultrasonic nozzle tip can be circular, oval, elliptical, rectangular, multi-angular, trapezoidal, or a combination thereof. The distal end shape of the ultrasound nozzle tip may be the same or different, such as rectangular, elliptical, oval, spherical, conical, curved, stepped, with chamfer, etc. The most preferred shape is rectangular, due to radiation beams from the ultrasonic nozzle tip surface being fully directed to the target (wound). With the spherical, elliptical and oval shaped ends, radiation beams are focussed at a focal point, as shown, for example, in FIG. 4. With distal ends of other shapes, some of the radiation beams spread before reaching the target.
- Radial side surface(FIG. 5) of distal end and central orifice (FIG. 6) of the ultrasond tip may have slot (groove)or thread for liquid to be directed to the radiation surface, which increases the liquid pressure.
- Since local tissue oxygenation can stimulate tissue regeneration and prevent infection in wound treatment, the method of the present invention includes the mixing and delivery of oxygen and sprayed liquid (saline, water, therapeutic agent, etc., a shown, for example, in FIG. 7. In this case the liquid spray delivers oxygen or another gas to the wound. Gas or liquid can be delivered via tubing (FIG. 7) or housing (FIG. 8).
- The step of producing the spray can further include operating the transducer to produce ultrasonic waves having a frequency of from about 18 to 10000 kHz. Although a frequency of 1 to 18 kHz can be used, this range should be avoided since this range of sound wave is uncomfortable to the patient and operator. The preferred range of frequency is from about 30 to 100 kilohertz, the most preferred frequency being about 40 kHz.
- The distance of separation between the distal free end surface of the transducer and the surface to be sprayed is preferably from about 0.1 to 20 inches.
- One of the benefits of the present invention is the use of the ultrasound standing waves for wound treatment.
Ultrasound standing waves 210 occur when an ultrasound nozzle tip is activated through the air toward the wound surface as a result of incident and reflected waves from the wound surface, which creates ultrasonic radiation pressure.Standing waves 210, actually ultrasound radiation pressure, occur when the distance between the distal end of the transducer nozzle tip (as a radiant of ultrasound waves) and the reflected surface (wound surface) is: n.λ/2 (λ=wave length, n=integer). To reach this preferred distance and therefore this effect in wound treatment practice, the ultrasound transducer or tip must be moved back and forth toward the wound by the operator. - The standing waves are more effective in limited space or area as a tube. In this case use of a bushing12 (FIG. 9) increases ultrasound radiation pressure. The bushing may or may not be disposable part on the distal end.
- The liquid can further include any drug (antibiotic, anticeptic, etc.), saline, water (distilled or regular), or oil for application to the tissue.
- In addition, the method of the invention can include directing the spray onto the surface for from about 1 second to about 30 minutes, dependant upon the condition and size of the wound. This can be done on a daily or semi daily basis, or two-three times per week or month.
- The method of the present invention permits application of ultrasonic waves to the wound without establishing contact, directly or indirectly, between the ultrasonic transducer and the wound. For example, surfaces of the human body especially suited for treatment with the method of the present invention include infected and/or inflamed situations in open wounds, including trauma or gun shut wounds, and fire and chemical bums.
- In addition, the method of the present invention is particularly suited to directing a spray into orifices or other body crevices that are difficult to access.
- This method of wound treatment has a several advantages. First, this method topically applies medicines such as liquid antibiotics to the wound surface without the need to contact an infected, inflamed or painful tissue with an instrument. Second, a significant debridement, cleansing and bactericidal effect can occur, when spraying a wound surface using the method of the present invention. And third, aside from the bactericidal effect and advantages of non-contact treatment, use of the method of the present invention permits a significant reduction in volume used of liquid medicine used as compared with traditional methods for wound treatment. Similarly, this allows for precise dosage of the sprayed liquid to permit a user, such as a physician to administer the desired volume of liquid at a desired rate and duration.
- The method of the present invention decreases healing times for inflammatory and purulent infected wounds, up to 1.5 to 2 times faster than traditional methods. This effect results from a bactericidal, blood flow increasing and mechanical cleansing effect of the atomized spray particles, which have ultrasound energy due to the ultrasonic waves.
- The ultrasonic spray mechanically scrubs the surface of tissue to remove dirt, dead tissue, and purulent buildup on the tissue surface.
- The mentioned healing effect also results of energized and highly activated antibiotics, drug penetration into the tissue surface up to 0.5 mm in depth under influence of ultrasound waves. Additionally, a combination of the low frequency ultrasonic waves and the sonicated medicines (highly activated by ultrasonic energy) destroy the surface bacteria to result in a higher disinfecting property of sonicated liquids as compared to ordinarily applied liquids. The spray of the present method also stimulates healthy cell growth to aid in granulization and epithelization of the healing tissue. Other applications of the method can be directed to non-medical uses such as cleansing, sterilizing and coating surfaces of objects and food. The method of the present invention offers an approach that may re-establish use of some traditional antibiotics and establish a method fighting bacteria without antibiotics when necessary.
- The effect of the method of the present invention in highly activating antibiotics may allow some traditional antibiotics to overcome bacteria which have become resistant to that antibiotic. Moreover, independent of the sonication effect of the antibiotics, the low frequency ultrasonic waves applied in the method of the present invention physically destroy bacteria. The combination of the highly activated antibiotics and of the low frequency ultrasonic waves in the method of the present invention produce a strong bactericidal effect not found in mere topically application or orally ingested antibiotics. This combined effect has been shown to significantly increase the healing of purulent infected wounds.
- The present method also provides a system of non-contact drug delivery without using a compression sprayer system. This simplifies the design of a non-contact drug delivery sprayer and reduces the weight of the sprayer. More importantly, not using compression to propel the atomized particles preserves the ultrasound energy carried by the spray particles.
- The method of the present invention provides a method of compressionless non-contact drug delivery.
- It is to be understood, however, that other expedients known to those skilled in the art or disclosed herein, may be employed without departing from the spirit of the invention or the scope of the appended claims.
Claims (22)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/840,416 US6478754B1 (en) | 2001-04-23 | 2001-04-23 | Ultrasonic method and device for wound treatment |
PCT/US2002/012138 WO2002085456A1 (en) | 2001-04-23 | 2002-04-18 | Ultrasonic method and device for wound treatment |
US10/214,339 US6663554B2 (en) | 2001-04-23 | 2002-08-07 | Ultrasonic method and device for wound treatment |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/840,416 US6478754B1 (en) | 2001-04-23 | 2001-04-23 | Ultrasonic method and device for wound treatment |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/214,339 Continuation US6663554B2 (en) | 2001-04-23 | 2002-08-07 | Ultrasonic method and device for wound treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
US20020156400A1 true US20020156400A1 (en) | 2002-10-24 |
US6478754B1 US6478754B1 (en) | 2002-11-12 |
Family
ID=25282320
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/840,416 Expired - Lifetime US6478754B1 (en) | 2001-04-23 | 2001-04-23 | Ultrasonic method and device for wound treatment |
US10/214,339 Expired - Lifetime US6663554B2 (en) | 2001-04-23 | 2002-08-07 | Ultrasonic method and device for wound treatment |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/214,339 Expired - Lifetime US6663554B2 (en) | 2001-04-23 | 2002-08-07 | Ultrasonic method and device for wound treatment |
Country Status (2)
Country | Link |
---|---|
US (2) | US6478754B1 (en) |
WO (1) | WO2002085456A1 (en) |
Cited By (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020016557A1 (en) * | 1997-02-14 | 2002-02-07 | Duarte Luiz R. | Ultrasonic treatment for wounds |
WO2004110649A1 (en) * | 2003-06-18 | 2004-12-23 | Abb Patent Gmbh | Standing ultrasonic wave spraying arrangement |
US20050038377A1 (en) * | 2000-08-24 | 2005-02-17 | Redding Bruce K. | Ultrasonically enhanced substance delivery system and device |
US20050075599A1 (en) * | 2001-08-24 | 2005-04-07 | Redding Bruce K. | Ultrasonically enhanced saline treatment for burn damaged skin |
US20060015059A1 (en) * | 2002-01-16 | 2006-01-19 | Redding Bruce K Jr | Substance delivery device |
US20060089632A1 (en) * | 2004-10-06 | 2006-04-27 | Guided Therapy Systems, L.L.C. | Method and system for treating acne and sebaceous glands |
US20060184071A1 (en) * | 1997-12-29 | 2006-08-17 | Julia Therapeutics, Llc | Treatment of skin with acoustic energy |
WO2007084792A3 (en) * | 2006-01-23 | 2007-12-13 | Kci Licensing Inc | System and method for treating a wound using ultrasonic debribement |
US20080027328A1 (en) * | 1997-12-29 | 2008-01-31 | Julia Therapeutics, Llc | Multi-focal treatment of skin with acoustic energy |
WO2008024532A1 (en) * | 2006-08-21 | 2008-02-28 | Boston Scientific Scimed, Inc. | Ultrasound catheter |
US20080095920A1 (en) * | 2005-08-04 | 2008-04-24 | Eilaz Babaev | Ultrasound medical device coating method |
US20080119779A1 (en) * | 2006-09-29 | 2008-05-22 | Eilaz Babaev | Method of Treating Lumens, Cavities, and Tissues of the Body with an Ultrasound Delivered Liquid. |
WO2008036622A3 (en) * | 2006-09-18 | 2008-05-22 | Guided Therapy Systems Llc | Method and system for non-ablative acne treatment and prevention |
US20080128362A1 (en) * | 2006-12-04 | 2008-06-05 | Bacoustics Llc | Method of ultrasonically treating a continuous flow of fluid |
US20080146970A1 (en) * | 2005-12-06 | 2008-06-19 | Julia Therapeutics, Llc | Gel dispensers for treatment of skin with acoustic energy |
US20080243047A1 (en) * | 2007-03-27 | 2008-10-02 | Babaev Eilaz P | Ultrasound wound care device |
US20090005710A1 (en) * | 2004-10-01 | 2009-01-01 | Duplogen, Inc. | Ultrasonic Equipment for Treatment of Osteoarthritis |
US20090099485A1 (en) * | 2007-10-16 | 2009-04-16 | Sarvazyan Armen P | Ultrasound standing wave method and apparatus for tissue treatment |
US20090200390A1 (en) * | 2008-02-12 | 2009-08-13 | Eilaz Babaev | Ultrasound atomization system |
US20090312673A1 (en) * | 2008-06-14 | 2009-12-17 | Vytronus, Inc. | System and method for delivering energy to tissue |
US20090312693A1 (en) * | 2008-06-13 | 2009-12-17 | Vytronus, Inc. | System and method for delivering energy to tissue |
US20100063423A1 (en) * | 2006-12-19 | 2010-03-11 | Cedars-Sinai Medical Center | Ultrasonic bath to increase tissue perfusion |
WO2010067239A3 (en) * | 2008-12-11 | 2010-08-05 | Koninklijke Philips Electronics, N.V. | System and method for monitoring nebulization of a medicament |
US7789841B2 (en) | 1997-02-06 | 2010-09-07 | Exogen, Inc. | Method and apparatus for connective tissue treatment |
US7819918B2 (en) * | 2001-07-16 | 2010-10-26 | Depuy Products, Inc. | Implantable tissue repair device |
US7842249B2 (en) | 2006-03-29 | 2010-11-30 | Bacoustics, Llc | Apparatus for vaccine development using ultrasound technology |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
AU2005205820B2 (en) * | 2004-09-04 | 2011-04-14 | Smith & Nephew Plc | Ultrasound device and method of use |
US7950594B2 (en) | 2008-02-11 | 2011-05-31 | Bacoustics, Llc | Mechanical and ultrasound atomization and mixing system |
US8016208B2 (en) | 2008-02-08 | 2011-09-13 | Bacoustics, Llc | Echoing ultrasound atomization and mixing system |
US8166332B2 (en) | 2005-04-25 | 2012-04-24 | Ardent Sound, Inc. | Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power |
US8235919B2 (en) | 2001-01-12 | 2012-08-07 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
US8282554B2 (en) | 2004-10-06 | 2012-10-09 | Guided Therapy Systems, Llc | Methods for treatment of sweat glands |
US8409097B2 (en) | 2000-12-28 | 2013-04-02 | Ardent Sound, Inc | Visual imaging system for ultrasonic probe |
WO2013067041A1 (en) * | 2011-11-01 | 2013-05-10 | Indrani Deo | Dispensing nozzle with an ultrasound activator |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US8460193B2 (en) | 2004-10-06 | 2013-06-11 | Guided Therapy Systems Llc | System and method for ultra-high frequency ultrasound treatment |
US8480585B2 (en) | 1997-10-14 | 2013-07-09 | Guided Therapy Systems, Llc | Imaging, therapy and temperature monitoring ultrasonic system and method |
US8491521B2 (en) * | 2007-01-04 | 2013-07-23 | Celleration, Inc. | Removable multi-channel applicator nozzle |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US8636665B2 (en) | 2004-10-06 | 2014-01-28 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of fat |
US8663112B2 (en) | 2004-10-06 | 2014-03-04 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
US8708935B2 (en) | 2004-09-16 | 2014-04-29 | Guided Therapy Systems, Llc | System and method for variable depth ultrasound treatment |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
CN103800955A (en) * | 2012-11-09 | 2014-05-21 | 苏州工业园区职业技术学院 | Ultrasonic wave trauma cleaning equipment |
US8764687B2 (en) | 2007-05-07 | 2014-07-01 | Guided Therapy Systems, Llc | Methods and systems for coupling and focusing acoustic energy using a coupler member |
CN104027894A (en) * | 2014-06-17 | 2014-09-10 | 南京航空航天大学 | Method for improving infiltration capacity of thrombolytic drug at thrombus part |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US8858471B2 (en) | 2011-07-10 | 2014-10-14 | Guided Therapy Systems, Llc | Methods and systems for ultrasound treatment |
US8915870B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US9011337B2 (en) | 2011-07-11 | 2015-04-21 | Guided Therapy Systems, Llc | Systems and methods for monitoring and controlling ultrasound power output and stability |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
USD733321S1 (en) | 2014-01-10 | 2015-06-30 | Celleration, Inc. | Ultrasonic treatment device |
USD733319S1 (en) | 2014-01-10 | 2015-06-30 | Celleration, Inc. | Ultrasonic treatment wand |
US9114247B2 (en) | 2004-09-16 | 2015-08-25 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment with a multi-directional transducer |
US9149658B2 (en) | 2010-08-02 | 2015-10-06 | Guided Therapy Systems, Llc | Systems and methods for ultrasound treatment |
US9216276B2 (en) | 2007-05-07 | 2015-12-22 | Guided Therapy Systems, Llc | Methods and systems for modulating medicants using acoustic energy |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US9744315B1 (en) * | 2016-11-28 | 2017-08-29 | Heat In A Click LLC | Skin treatment apparatus |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
CN109567760A (en) * | 2019-01-25 | 2019-04-05 | 高密市人民医院 | A kind of care device for the monitoring processing of hand wound |
US10420960B2 (en) | 2013-03-08 | 2019-09-24 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US10537304B2 (en) | 2008-06-06 | 2020-01-21 | Ulthera, Inc. | Hand wand for ultrasonic cosmetic treatment and imaging |
US10561862B2 (en) | 2013-03-15 | 2020-02-18 | Guided Therapy Systems, Llc | Ultrasound treatment device and methods of use |
US10603521B2 (en) | 2014-04-18 | 2020-03-31 | Ulthera, Inc. | Band transducer ultrasound therapy |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
CN113798110A (en) * | 2021-10-25 | 2021-12-17 | 方翠仙 | Ultrasonic spraying equipment for automobile glass waterproof film |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US11224767B2 (en) | 2013-11-26 | 2022-01-18 | Sanuwave Health, Inc. | Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing |
US11224895B2 (en) | 2016-01-18 | 2022-01-18 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US11241218B2 (en) | 2016-08-16 | 2022-02-08 | Ulthera, Inc. | Systems and methods for cosmetic ultrasound treatment of skin |
CN114224620A (en) * | 2021-12-21 | 2022-03-25 | 田艳春 | Debridement nursing device in operating room nursing |
CN114618736A (en) * | 2022-01-26 | 2022-06-14 | 北京航空航天大学 | Ultrasonic spraying device and ultrasonic spraying system |
US11717661B2 (en) | 2007-05-07 | 2023-08-08 | Guided Therapy Systems, Llc | Methods and systems for ultrasound assisted delivery of a medicant to tissue |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US11944849B2 (en) | 2018-02-20 | 2024-04-02 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
US11969609B2 (en) | 2022-12-05 | 2024-04-30 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL137689A0 (en) * | 2000-08-03 | 2001-10-31 | L R Res & Dev Ltd | System for enhanced chemical debridement |
US6964647B1 (en) * | 2000-10-06 | 2005-11-15 | Ellaz Babaev | Nozzle for ultrasound wound treatment |
US7914470B2 (en) * | 2001-01-12 | 2011-03-29 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
US6960173B2 (en) * | 2001-01-30 | 2005-11-01 | Eilaz Babaev | Ultrasound wound treatment method and device using standing waves |
US7544177B2 (en) * | 2002-01-24 | 2009-06-09 | The Regents Of The University Of California | Aerosol device to deliver bioactive agent |
US8001962B2 (en) * | 2002-08-23 | 2011-08-23 | Sheiman Ultrasonic Research Foundation Pty Ltd. | Nebulizing and drug delivery device |
US20060169202A1 (en) * | 2003-03-28 | 2006-08-03 | Erickson Stuart J | Coating system |
US7934665B2 (en) * | 2003-03-28 | 2011-05-03 | Ultrasonic Systems Inc. | Ultrasonic spray coating system |
WO2004087336A2 (en) * | 2003-03-28 | 2004-10-14 | Ultrasonic Systems Inc. | Ultrasonic spray coating system |
US20040267234A1 (en) * | 2003-04-16 | 2004-12-30 | Gill Heart | Implantable ultrasound systems and methods for enhancing localized delivery of therapeutic substances |
IL155546A (en) * | 2003-04-22 | 2010-06-16 | Healfus Ltd | Apparatus for treatment of damaged tissue |
US20060058708A1 (en) * | 2003-12-24 | 2006-03-16 | Gill Heart | Method and apparatus for ultrasonically increasing the transportation of therapeutic substances through tissue |
US8368867B2 (en) * | 2004-12-31 | 2013-02-05 | Lg Display Co., Ltd. | Liquid crystal spraying apparatus with ultrasonic converter within nozzle and method for manufacturing of liquid crystal display device using the same |
US8056557B2 (en) * | 2005-03-09 | 2011-11-15 | Ric Investments, Llc | Nebulizing drug delivery device with barrier |
US7631643B2 (en) * | 2005-03-09 | 2009-12-15 | Ric Investments, Llc | Nebulizing drug delivery device with interlock detection and temperature protection |
US7814901B2 (en) * | 2005-03-09 | 2010-10-19 | Ric Investments, Llc | Nebulizing drug delivery device with increased flow rate |
US7721729B2 (en) * | 2005-03-09 | 2010-05-25 | Ric Investments, Llc | Nebulizing drug delivery device for ventilator |
US9339836B2 (en) | 2005-05-23 | 2016-05-17 | Biosonic Australia Pty Ltd | Ultrasonic atomization apparatus |
US7713218B2 (en) | 2005-06-23 | 2010-05-11 | Celleration, Inc. | Removable applicator nozzle for ultrasound wound therapy device |
US7785277B2 (en) | 2005-06-23 | 2010-08-31 | Celleration, Inc. | Removable applicator nozzle for ultrasound wound therapy device |
US9101949B2 (en) | 2005-08-04 | 2015-08-11 | Eilaz Babaev | Ultrasonic atomization and/or seperation system |
US7896539B2 (en) | 2005-08-16 | 2011-03-01 | Bacoustics, Llc | Ultrasound apparatus and methods for mixing liquids and coating stents |
US7572268B2 (en) * | 2005-10-13 | 2009-08-11 | Bacoustics, Llc | Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy |
US7842032B2 (en) * | 2005-10-13 | 2010-11-30 | Bacoustics, Llc | Apparatus and methods for the selective removal of tissue |
US20070167826A1 (en) * | 2005-11-30 | 2007-07-19 | Warren Lee | Apparatuses for thermal management of actuated probes, such as catheter distal ends |
US20070167825A1 (en) * | 2005-11-30 | 2007-07-19 | Warren Lee | Apparatus for catheter tips, including mechanically scanning ultrasound probe catheter tip |
US20070167824A1 (en) * | 2005-11-30 | 2007-07-19 | Warren Lee | Method of manufacture of catheter tips, including mechanically scanning ultrasound probe catheter tip, and apparatus made by the method |
EP1804308B1 (en) * | 2005-12-23 | 2012-04-04 | Novaled AG | An organic light emitting device with a plurality of organic electroluminescent units stacked upon each other |
US7691101B2 (en) * | 2006-01-06 | 2010-04-06 | Arthrocare Corporation | Electrosurgical method and system for treating foot ulcer |
US8876746B2 (en) | 2006-01-06 | 2014-11-04 | Arthrocare Corporation | Electrosurgical system and method for treating chronic wound tissue |
US8920849B1 (en) * | 2006-03-30 | 2014-12-30 | Kenneth P. Callison | Skin treatment method and system |
US7662177B2 (en) | 2006-04-12 | 2010-02-16 | Bacoustics, Llc | Apparatus and methods for pain relief using ultrasound waves in combination with cryogenic energy |
US20100313883A1 (en) * | 2006-04-20 | 2010-12-16 | Koninklijke Philips Electronics N.V. | Ultrasonic bebulilzer with metal coated ultrasonic genrator |
EP2020943B1 (en) | 2006-05-30 | 2015-07-08 | ArthroCare Corporation | Hard tissue ablation system |
US7431704B2 (en) * | 2006-06-07 | 2008-10-07 | Bacoustics, Llc | Apparatus and method for the treatment of tissue with ultrasound energy by direct contact |
CA2654316C (en) * | 2006-06-07 | 2015-04-07 | Trinity Wound Institute, Llc | Oxygen therapy with ultrasound |
US8562547B2 (en) | 2006-06-07 | 2013-10-22 | Eliaz Babaev | Method for debriding wounds |
US20080039727A1 (en) * | 2006-08-08 | 2008-02-14 | Eilaz Babaev | Ablative Cardiac Catheter System |
US20080097252A1 (en) * | 2006-08-25 | 2008-04-24 | Eilaz Babaev | Ultrasound and Pressure Therapy Wound Care Device |
AU2007286660A1 (en) * | 2006-08-25 | 2008-02-28 | Eilaz Babaev | Portable ultrasound device for the treatment of wounds |
US20080167584A1 (en) * | 2007-01-04 | 2008-07-10 | Lenhardt Martin L | Transdermal ultrasonic antimicrobial treatment and method |
US8192424B2 (en) | 2007-01-05 | 2012-06-05 | Arthrocare Corporation | Electrosurgical system with suction control apparatus, system and method |
US20080265052A1 (en) * | 2007-04-30 | 2008-10-30 | Ke-Ming Quan | Method of using an ultrasonic spray apparatus to coat a substrate |
US20080265056A1 (en) * | 2007-04-30 | 2008-10-30 | Ke-Ming Quan | Ultrasonic spray apparatus to coat a substrate |
US7780095B2 (en) | 2007-07-13 | 2010-08-24 | Bacoustics, Llc | Ultrasound pumping apparatus |
US7753285B2 (en) | 2007-07-13 | 2010-07-13 | Bacoustics, Llc | Echoing ultrasound atomization and/or mixing system |
US7896854B2 (en) * | 2007-07-13 | 2011-03-01 | Bacoustics, Llc | Method of treating wounds by creating a therapeutic solution with ultrasonic waves |
US7901388B2 (en) | 2007-07-13 | 2011-03-08 | Bacoustics, Llc | Method of treating wounds by creating a therapeutic solution with ultrasonic waves |
US20090093870A1 (en) * | 2007-10-05 | 2009-04-09 | Bacoustics, Llc | Method for Holding a Medical Device During Coating |
US8689728B2 (en) * | 2007-10-05 | 2014-04-08 | Menendez Adolfo | Apparatus for holding a medical device during coating |
US20090098015A1 (en) * | 2007-10-15 | 2009-04-16 | Bhardwaj Mahesh C | Ultrasonic Breathing and Respiratory System and Method |
US20090099486A1 (en) * | 2007-10-16 | 2009-04-16 | Bhardwaj Mahesh C | Ultrasonically Gas-Charged Reaction Accelerator |
US9358063B2 (en) | 2008-02-14 | 2016-06-07 | Arthrocare Corporation | Ablation performance indicator for electrosurgical devices |
AU2009244462B2 (en) | 2008-05-06 | 2013-04-11 | Cook Medical Technologies Llc | Apparatus and methods for delivering therapeutic agents |
US8048095B2 (en) * | 2008-06-09 | 2011-11-01 | Bacoustics, Llc | Ultrasound liquid blade scalpel device |
US20090306694A1 (en) * | 2008-06-10 | 2009-12-10 | Eilaz Babaev | Ultrasound Liquid Blade Scalpel Method |
ES2736276T3 (en) * | 2008-07-14 | 2019-12-27 | Arizona Board Of Regents For And On Behalf Of Arizona State Univ | Cellular activity modulation devices using ultrasound |
US8323220B2 (en) * | 2008-09-19 | 2012-12-04 | Eilaz Babaev | Spider vein treatment apparatus |
US8376969B2 (en) * | 2008-09-22 | 2013-02-19 | Bacoustics, Llc | Methods for treatment of spider veins |
EP2373234A1 (en) | 2008-12-16 | 2011-10-12 | Aardvark Medical, Inc. | Methods and systems for delivery of fluids, aerosols and acoustic energy to tissue surfaces, cavities and obstructed passages such as intranasal ostia |
EP2375960B1 (en) | 2008-12-23 | 2018-10-31 | Cook Medical Technologies LLC | Apparatus for containing and delivering therapeutic agents |
US8574187B2 (en) | 2009-03-09 | 2013-11-05 | Arthrocare Corporation | System and method of an electrosurgical controller with output RF energy control |
US8118777B2 (en) | 2009-05-29 | 2012-02-21 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US9101744B2 (en) | 2009-05-29 | 2015-08-11 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
US8257350B2 (en) | 2009-06-17 | 2012-09-04 | Arthrocare Corporation | Method and system of an electrosurgical controller with wave-shaping |
US20110130615A1 (en) * | 2009-12-02 | 2011-06-02 | Mishelevich David J | Multi-modality neuromodulation of brain targets |
US20110178442A1 (en) * | 2010-01-18 | 2011-07-21 | Mishelevich David J | Patient feedback for control of ultrasound deep-brain neuromodulation |
US20110190668A1 (en) * | 2010-02-03 | 2011-08-04 | Mishelevich David J | Ultrasound neuromodulation of the sphenopalatine ganglion |
US20110112394A1 (en) * | 2009-11-11 | 2011-05-12 | Mishelevich David J | Neuromodulation of deep-brain targets using focused ultrasound |
US8372067B2 (en) | 2009-12-09 | 2013-02-12 | Arthrocare Corporation | Electrosurgery irrigation primer systems and methods |
US20110172591A1 (en) * | 2010-01-13 | 2011-07-14 | Bacoustics Llc | Portable topical hyperbaric skin therapy and wound treatment system |
US8747399B2 (en) | 2010-04-06 | 2014-06-10 | Arthrocare Corporation | Method and system of reduction of low frequency muscle stimulation during electrosurgical procedures |
US8685018B2 (en) | 2010-10-15 | 2014-04-01 | Arthrocare Corporation | Electrosurgical wand and related method and system |
US9131597B2 (en) | 2011-02-02 | 2015-09-08 | Arthrocare Corporation | Electrosurgical system and method for treating hard body tissue |
CN102836471A (en) * | 2011-06-20 | 2012-12-26 | 重庆腾跃医疗器械有限公司 | Multifunctional ultrasonic debridement treatment machine |
US9042201B2 (en) | 2011-10-21 | 2015-05-26 | Thync, Inc. | Method and system for direct communication |
RU2481160C1 (en) * | 2011-11-18 | 2013-05-10 | Общество с ограниченной ответственностью "Центр ультразвуковых технологий АлтГТУ" | Ultrasound sprayer |
US20130264397A1 (en) * | 2012-04-09 | 2013-10-10 | Stuart J. Erickson | Spray Head Improvements for an Ultrasonic Spray Coating Assembly |
WO2014036170A1 (en) | 2012-08-29 | 2014-03-06 | Thync, Inc. | Systems and devices for coupling ultrasound energy to a body |
US9693818B2 (en) | 2013-03-07 | 2017-07-04 | Arthrocare Corporation | Methods and systems related to electrosurgical wands |
US9713489B2 (en) | 2013-03-07 | 2017-07-25 | Arthrocare Corporation | Electrosurgical methods and systems |
US9801678B2 (en) | 2013-03-13 | 2017-10-31 | Arthrocare Corporation | Method and system of controlling conductive fluid flow during an electrosurgical procedure |
US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
US11931227B2 (en) | 2013-03-15 | 2024-03-19 | Cook Medical Technologies Llc | Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding |
US9282803B2 (en) * | 2013-10-03 | 2016-03-15 | Donald John Ciervo | Ultrasonic cosmetic applicator |
US9597702B1 (en) * | 2013-10-03 | 2017-03-21 | Sonaer, Inc. | Ultrasonic cosmetic applicator |
DE102015201092B4 (en) * | 2015-01-22 | 2016-10-06 | Jens-Christian Frohwitter | Device and system for ultrasonic treatment of open wounds |
CA3001619A1 (en) | 2015-10-30 | 2017-05-04 | Johnson & Johnson Consumer Inc. | Unit dose aseptic aerosol misting device |
US20170128972A1 (en) | 2015-10-30 | 2017-05-11 | Johnson & Johnson Consumer Inc. | Aseptic aerosol misting device |
MA54688A (en) | 2015-10-30 | 2021-11-17 | Johnson & Johnson Consumer Inc | ASEPTIC AEROSOL NEBULIZER |
KR102645914B1 (en) | 2015-10-30 | 2024-03-12 | 존슨 앤드 존슨 컨수머 인코포레이티드 | Sterile Aerosol Misting Device |
CN107670156A (en) * | 2017-11-08 | 2018-02-09 | 南通大学附属医院 | A kind of painless anesthesia syringe |
CN111939045A (en) * | 2019-05-17 | 2020-11-17 | 彭志军 | Centralized medicine supply ultrasonic massage medicine applying device |
Family Cites Families (135)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB807080A (en) * | 1956-02-28 | 1959-01-07 | Technical Ceramics Ltd | Ultrasonic spray |
US3275059A (en) | 1965-05-10 | 1966-09-27 | Little Inc A | Nozzle system and fuel oil burner incorporating it |
US3392916A (en) | 1965-12-08 | 1968-07-16 | Carl Gunnar Daniel Engstrom | Ultrasonic atomizer |
US3561444A (en) | 1968-05-22 | 1971-02-09 | Bio Logics Inc | Ultrasonic drug nebulizer |
US3860173A (en) | 1970-02-03 | 1975-01-14 | Naoyasu Sata | Non-polluting combustion engine having ultrasonic fuel atomizer in place of carburetor |
US4085893A (en) | 1974-03-20 | 1978-04-25 | Durley Iii Benton A | Ultrasonic humidifiers, atomizers and the like |
GB1496086A (en) | 1975-02-19 | 1977-12-21 | Plessey Co Ltd | Vibratory atomizer |
US4309989A (en) | 1976-02-09 | 1982-01-12 | The Curators Of The University Of Missouri | Topical application of medication by ultrasound with coupling agent |
US4153201A (en) | 1976-11-08 | 1979-05-08 | Sono-Tek Corporation | Transducer assembly, ultrasonic atomizer and fuel burner |
US4301968A (en) | 1976-11-08 | 1981-11-24 | Sono-Tek Corporation | Transducer assembly, ultrasonic atomizer and fuel burner |
DE2811248C3 (en) | 1978-03-15 | 1981-11-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Liquid atomizer |
FR2443113B1 (en) | 1978-06-30 | 1985-12-06 | Deutsch Pruef Messgeraete | METHOD AND DEVICE FOR TRANSMITTING ACOUSTIC PULSES, PARTICULARLY IN THE FIELD OF ULTRA-SOUNDS, AND APPLICATION OF SUCH PULSES IN PARTICULAR TO NON-DESTRUCTIVE CONTROL OF MATERIALS |
GB2029270B (en) | 1978-07-11 | 1982-11-03 | Plessey Co Ltd | Vibratory atomiser |
DE2854841C2 (en) | 1978-12-19 | 1981-03-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Liquid atomizer, preferably inhalation device |
JPS5848225B2 (en) | 1979-01-09 | 1983-10-27 | オムロン株式会社 | Atomization amount control method of ultrasonic liquid atomization device |
DE7917568U1 (en) | 1979-06-19 | 1979-09-20 | Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart | INHALATION DEVICE |
GB2058209B (en) | 1979-09-11 | 1983-04-27 | Plessey Co Ltd | Method of producing a fuel injector for an engine |
US4352459A (en) | 1979-11-13 | 1982-10-05 | Sono-Tek Corporation | Ultrasonic liquid atomizer having an axially-extending liquid feed passage |
NL8202262A (en) | 1981-06-06 | 1983-01-03 | Rowenta Werke Gmbh | TRANSPORTATION FOR ULTRASONIC RESPIRATORS AND THE LIKE. |
FR2507087B1 (en) | 1981-06-06 | 1986-06-27 | Rowenta Werke Gmbh | ULTRASONIC INHALER |
DE3124854C2 (en) | 1981-06-24 | 1985-03-14 | Reinhard 8057 Eching Mühlbauer | High pressure injection system with ultrasonic atomization |
BR8107560A (en) | 1981-11-19 | 1983-07-05 | Luiz Romariz Duarte | ULTRASONIC STIMULATION OF BONE FRACTURE CONSOLIDATION |
US4541564A (en) | 1983-01-05 | 1985-09-17 | Sono-Tek Corporation | Ultrasonic liquid atomizer, particularly for high volume flow rates |
US4655393A (en) | 1983-01-05 | 1987-04-07 | Sonotek Corporation | High volume ultrasonic liquid atomizer |
GB8316051D0 (en) | 1983-06-13 | 1983-07-20 | Shell Int Research | Atomiser |
EP0156409A3 (en) | 1984-02-23 | 1986-06-25 | Jean Michel Anthony | Device for moistening parts of the human body |
JPS60222552A (en) | 1984-04-19 | 1985-11-07 | Toa Nenryo Kogyo Kk | Ultrasonic injection method and injection valve |
DE3574344D1 (en) | 1984-08-29 | 1989-12-28 | Omron Tateisi Electronics Co | Ultrasonic atomizer |
EP0174033B1 (en) | 1984-09-07 | 1991-03-27 | OMRON Corporation | Oscillating construction for an ultrasonic atomizing inhaler |
US4582654A (en) | 1984-09-12 | 1986-04-15 | Varian Associates, Inc. | Nebulizer particularly adapted for analytical purposes |
JPS61138559A (en) | 1984-12-11 | 1986-06-26 | Toa Nenryo Kogyo Kk | Oscillator for ultrasonic wave injection nozzle |
JPS61138558A (en) | 1984-12-11 | 1986-06-26 | Toa Nenryo Kogyo Kk | Oscillator for ultrasonic wave injection nozzle |
US4726523A (en) | 1984-12-11 | 1988-02-23 | Toa Nenryo Kogyo Kabushiki Kaisha | Ultrasonic injection nozzle |
JPS61259784A (en) | 1985-05-13 | 1986-11-18 | Toa Nenryo Kogyo Kk | Vibrator for ultrasonic injection |
US4642581A (en) | 1985-06-21 | 1987-02-10 | Sono-Tek Corporation | Ultrasonic transducer drive circuit |
US4659014A (en) | 1985-09-05 | 1987-04-21 | Delavan Corporation | Ultrasonic spray nozzle and method |
US4723708A (en) * | 1986-05-09 | 1988-02-09 | Sono-Tek Corporation | Central bolt ultrasonic atomizer |
US4941618A (en) | 1986-07-07 | 1990-07-17 | Leeman Labs Inc. | Nebulizer employing a fine mesh screen |
JPS6338193A (en) * | 1986-08-01 | 1988-02-18 | Toa Nenryo Kogyo Kk | Ultrasonic vibrator horn |
DE3627222A1 (en) | 1986-08-11 | 1988-02-18 | Siemens Ag | ULTRASONIC POCKET SPRAYER |
US5104042A (en) | 1986-08-27 | 1992-04-14 | Atochem North America, Inc. | Ultrasonic dispersion nozzle with internal shut-off mechanism having barrier-fluid separation means incorporated therewith |
US4930700A (en) | 1986-08-27 | 1990-06-05 | Atochem North America | Ultrasonic dispersion nozzle having internal shut-off mechanism with barrier fluid separation |
US4850534A (en) | 1987-05-30 | 1989-07-25 | Tdk Corporation | Ultrasonic wave nebulizer |
US5040537A (en) | 1987-11-24 | 1991-08-20 | Hitachi, Ltd. | Method and apparatus for the measurement and medical treatment using an ultrasonic wave |
DE3741201A1 (en) | 1987-12-02 | 1989-06-15 | Schering Ag | ULTRASONIC PROCESS AND METHOD FOR IMPLEMENTING IT |
FI82808C (en) | 1987-12-31 | 1991-04-25 | Etelae Haemeen Keuhkovammayhdi | Ultraljudfinfördelningsanordning |
US4905671A (en) | 1988-01-11 | 1990-03-06 | Dornier Medizintechnik Gmbh | Inducement of bone growth by acoustic shock waves |
US5186162A (en) | 1988-09-14 | 1993-02-16 | Interpore Orthopaedics, Inc. | Ultrasonic transducer device for treatment of living tissue and/or cells |
US5211160A (en) | 1988-09-14 | 1993-05-18 | Interpore Orthopaedics, Inc. | Ultrasonic orthopedic treatment head and body-mounting means therefor |
EP0373237A1 (en) | 1988-12-13 | 1990-06-20 | Siemens Aktiengesellschaft | Pocket inhaler device |
JPH03505424A (en) | 1989-04-14 | 1991-11-28 | アゼルバイジャンスキ ポリテフニチェスキ インスティテュト イメニ チェー.イルドリマ | Ultrasonic atomization device for liquid media |
US5002059A (en) | 1989-07-26 | 1991-03-26 | Boston Scientific Corporation | Tip filled ultrasound catheter |
US5163433A (en) | 1989-11-01 | 1992-11-17 | Olympus Optical Co., Ltd. | Ultrasound type treatment apparatus |
US4961885A (en) | 1989-11-24 | 1990-10-09 | Elecsys Ltd. | Ultrasonic nebulizer |
FR2655279B1 (en) | 1989-12-01 | 1993-09-17 | Anios Lab Sarl | PROCESS FOR MICRO-SPRAYING AN ULTRA-SOUND SOLUTION AND MICRO-DROPLET DIFFUSER IMPLEMENTING SAID DEVICE. |
US5115805A (en) | 1990-02-23 | 1992-05-26 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
US5231975A (en) | 1990-02-23 | 1993-08-03 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
US5197946A (en) | 1990-06-27 | 1993-03-30 | Shunro Tachibana | Injection instrument with ultrasonic oscillating element |
GB9015077D0 (en) | 1990-07-09 | 1990-08-29 | Riker Laboratories Inc | Inhaler |
FR2665849B1 (en) * | 1990-08-20 | 1995-03-24 | Dynamad | ULTRASONIC DEVICE FOR THE CONTINUOUS PRODUCTION OF PARTICLES. |
US5172692A (en) | 1990-12-05 | 1992-12-22 | Kulow Howard H | Method for inflammatory response management |
US5269291A (en) | 1990-12-10 | 1993-12-14 | Coraje, Inc. | Miniature ultrasonic transducer for plaque ablation |
US5324255A (en) | 1991-01-11 | 1994-06-28 | Baxter International Inc. | Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm |
US5316000A (en) | 1991-03-05 | 1994-05-31 | Technomed International (Societe Anonyme) | Use of at least one composite piezoelectric transducer in the manufacture of an ultrasonic therapy apparatus for applying therapy, in a body zone, in particular to concretions, to tissue, or to bones, of a living being and method of ultrasonic therapy |
AU6130694A (en) | 1991-03-05 | 1994-08-15 | Miris Medical Corporation | An automatic aerosol medication delivery system and methods |
EP0504881B2 (en) * | 1991-03-22 | 2000-11-08 | Katsuro Tachibana | Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same |
US5325860A (en) | 1991-11-08 | 1994-07-05 | Mayo Foundation For Medical Education And Research | Ultrasonic and interventional catheter and method |
GB2291605B (en) * | 1991-11-12 | 1996-05-01 | Medix Ltd | A nebuliser and nebuliser control system |
US5374266A (en) | 1991-11-27 | 1994-12-20 | Kabushiki Kaisha Morita Seisakusho | Medical laser treatment device |
US5529572A (en) | 1992-01-24 | 1996-06-25 | Medispec Ltd. | Method and apparatus particularly useful for treating osteoporosis |
US5993389A (en) | 1995-05-22 | 1999-11-30 | Ths International, Inc. | Devices for providing acoustic hemostasis |
US5362309A (en) | 1992-09-14 | 1994-11-08 | Coraje, Inc. | Apparatus and method for enhanced intravascular phonophoresis including dissolution of intravascular blockage and concomitant inhibition of restenosis |
US5318014A (en) | 1992-09-14 | 1994-06-07 | Coraje, Inc. | Ultrasonic ablation/dissolution transducer |
US5393296A (en) | 1992-12-09 | 1995-02-28 | Siemens Aktiengesellschaft | Method for the medical treatment of pathologic bone |
US5573497A (en) | 1994-11-30 | 1996-11-12 | Technomed Medical Systems And Institut National | High-intensity ultrasound therapy method and apparatus with controlled cavitation effect and reduced side lobes |
US6098620A (en) | 1993-01-29 | 2000-08-08 | Aradigm Corporation | Device for aerosolizing narcotics |
US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
US5707403A (en) | 1993-02-24 | 1998-01-13 | Star Medical Technologies, Inc. | Method for the laser treatment of subsurface blood vessels |
US5527350A (en) | 1993-02-24 | 1996-06-18 | Star Medical Technologies, Inc. | Pulsed infrared laser treatment of psoriasis |
DE4315282C2 (en) | 1993-05-07 | 1999-10-07 | Siemens Ag | Use of an acoustic pressure pulse source |
WO1995001137A1 (en) | 1993-06-29 | 1995-01-12 | Voges Innovation Pty. Ltd. | Dispenser |
CH686872A5 (en) | 1993-08-09 | 1996-07-31 | Disetronic Ag | Medical Inhalationsgeraet. |
GB9324250D0 (en) | 1993-11-25 | 1994-01-12 | Minnesota Mining & Mfg | Inhaler |
EP0657226B1 (en) | 1993-12-10 | 1998-02-04 | Siemens Aktiengesellschaft | Ultrasonic sprayer |
US5570682A (en) | 1993-12-14 | 1996-11-05 | Ethex International, Inc. | Passive inspiratory nebulizer system |
JPH07184907A (en) | 1993-12-28 | 1995-07-25 | Toshiba Corp | Ultrasonic treating device |
US5989245A (en) | 1994-03-21 | 1999-11-23 | Prescott; Marvin A. | Method and apparatus for therapeutic laser treatment |
US5616140A (en) | 1994-03-21 | 1997-04-01 | Prescott; Marvin | Method and apparatus for therapeutic laser treatment |
US5437606A (en) | 1994-03-28 | 1995-08-01 | Tsukamoto; Kenichi | Ultrasonic system to alleviate toothaches |
US5516043A (en) | 1994-06-30 | 1996-05-14 | Misonix Inc. | Ultrasonic atomizing device |
US6113570A (en) | 1994-09-09 | 2000-09-05 | Coraje, Inc. | Method of removing thrombosis in fistulae |
US5547459A (en) | 1994-10-25 | 1996-08-20 | Orthologic Corporation | Ultrasonic bone-therapy apparatus and method |
US5520612A (en) | 1994-12-30 | 1996-05-28 | Exogen, Inc. | Acoustic system for bone-fracture therapy |
US5556372A (en) | 1995-02-15 | 1996-09-17 | Exogen, Inc. | Apparatus for ultrasonic bone treatment |
US5626554A (en) | 1995-02-21 | 1997-05-06 | Exogen, Inc. | Gel containment structure |
US6014970A (en) | 1998-06-11 | 2000-01-18 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US5554172A (en) | 1995-05-09 | 1996-09-10 | The Larren Corporation | Directed energy surgical method and assembly |
US5730705A (en) | 1995-06-12 | 1998-03-24 | Talish; Roger J. | Ultrasonic treatment for bony ingrowth |
US5658323A (en) | 1995-07-12 | 1997-08-19 | Miller; Iain D. | Method and apparatus for dermatology treatment |
US5879376A (en) | 1995-07-12 | 1999-03-09 | Luxar Corporation | Method and apparatus for dermatology treatment |
US5947921A (en) | 1995-12-18 | 1999-09-07 | Massachusetts Institute Of Technology | Chemical and physical enhancers and ultrasound for transdermal drug delivery |
US6041253A (en) | 1995-12-18 | 2000-03-21 | Massachusetts Institute Of Technology | Effect of electric field and ultrasound for transdermal drug delivery |
AU4238096A (en) * | 1995-11-15 | 1997-06-05 | Aeropag Usa, Inc. | Method of spraying a surface using ultrasonic radiation |
US5735811A (en) | 1995-11-30 | 1998-04-07 | Pharmasonics, Inc. | Apparatus and methods for ultrasonically enhanced fluid delivery |
US5683432A (en) | 1996-01-11 | 1997-11-04 | Medtronic, Inc. | Adaptive, performance-optimizing communication system for communicating with an implanted medical device |
WO1997029701A1 (en) | 1996-02-15 | 1997-08-21 | Biosense Inc. | Catheter based surgery |
US5895362A (en) | 1996-02-23 | 1999-04-20 | Abbott Laboratories | Transdermal transport using ultrasonic standing waves |
US5762616A (en) | 1996-03-15 | 1998-06-09 | Exogen, Inc. | Apparatus for ultrasonic treatment of sites corresponding to the torso |
US5656016A (en) | 1996-03-18 | 1997-08-12 | Abbott Laboratories | Sonophoretic drug delivery system |
US5746756A (en) | 1996-06-03 | 1998-05-05 | Ethicon Endo-Surgery, Inc. | Internal ultrasonic tip amplifier |
US5699805A (en) | 1996-06-20 | 1997-12-23 | Mayo Foundation For Medical Education And Research | Longitudinal multiplane ultrasound transducer underfluid catheter system |
JP2002515786A (en) | 1996-06-28 | 2002-05-28 | ソントラ メディカル,エル.ピー. | Ultrasound enhancement of transdermal delivery |
US6024718A (en) | 1996-09-04 | 2000-02-15 | The Regents Of The University Of California | Intraluminal directed ultrasound delivery device |
US5835678A (en) | 1996-10-03 | 1998-11-10 | Emcore Corporation | Liquid vaporizer system and method |
US6251099B1 (en) * | 1996-11-27 | 2001-06-26 | The General Hospital Corporation | Compound delivery using impulse transients |
US5785972A (en) * | 1997-01-10 | 1998-07-28 | Tyler; Kathleen A. | Colloidal silver, honey, and helichrysum oil antiseptic composition and method of application |
US5904659A (en) | 1997-02-14 | 1999-05-18 | Exogen, Inc. | Ultrasonic treatment for wounds |
DE69821345T2 (en) | 1997-04-18 | 2004-09-30 | Exogen, Inc. | DEVICE FOR ULTRASONIC BONE TREATMENT |
WO1998048711A1 (en) | 1997-05-01 | 1998-11-05 | Ekos Corporation | Ultrasound catheter |
DE19718513C5 (en) | 1997-05-02 | 2010-06-02 | Sanuwave, Inc., | Device for generating acoustic shock waves, in particular for medical use |
US5879314A (en) | 1997-06-30 | 1999-03-09 | Cybersonics, Inc. | Transducer assembly and method for coupling ultrasonic energy to a body for thrombolysis of vascular thrombi |
DE19733838C2 (en) | 1997-08-04 | 2001-06-13 | Hmt Ag | Device for treatment with acoustic shock waves |
US6113558A (en) | 1997-09-29 | 2000-09-05 | Angiosonics Inc. | Pulsed mode lysis method |
US5954047A (en) | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
US6007499A (en) | 1997-10-31 | 1999-12-28 | University Of Washington | Method and apparatus for medical procedures using high-intensity focused ultrasound |
US6325769B1 (en) | 1998-12-29 | 2001-12-04 | Collapeutics, Llc | Method and apparatus for therapeutic treatment of skin |
CA2317777C (en) | 1998-01-08 | 2005-05-03 | Sontra Medical, Inc. | Sonophoretic enhanced transdermal transport |
US6158431A (en) | 1998-02-13 | 2000-12-12 | Tsi Incorporated | Portable systems and methods for delivery of therapeutic material to the pulmonary system |
US6102298A (en) | 1998-02-23 | 2000-08-15 | The Procter & Gamble Company | Ultrasonic spray coating application system |
US6206842B1 (en) | 1998-08-03 | 2001-03-27 | Lily Chen Tu | Ultrasonic operation device |
US6106547A (en) | 1998-09-22 | 2000-08-22 | Huei-Jung; Lien | Hot/cold dual-mold skin treatment apparatus |
US6061597A (en) | 1998-12-18 | 2000-05-09 | Robert D. Rieman | Method and device for healing bone fractures |
US6231528B1 (en) | 1999-01-15 | 2001-05-15 | Jonathan J. Kaufman | Ultrasonic and growth factor bone-therapy: apparatus and method |
US6206843B1 (en) | 1999-01-28 | 2001-03-27 | Ultra Cure Ltd. | Ultrasound system and methods utilizing same |
JP2000237275A (en) | 1999-02-24 | 2000-09-05 | Ya Man Ltd | Ultrasonic mist generating apparatus |
-
2001
- 2001-04-23 US US09/840,416 patent/US6478754B1/en not_active Expired - Lifetime
-
2002
- 2002-04-18 WO PCT/US2002/012138 patent/WO2002085456A1/en not_active Application Discontinuation
- 2002-08-07 US US10/214,339 patent/US6663554B2/en not_active Expired - Lifetime
Cited By (184)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8123707B2 (en) | 1997-02-06 | 2012-02-28 | Exogen, Inc. | Method and apparatus for connective tissue treatment |
US7789841B2 (en) | 1997-02-06 | 2010-09-07 | Exogen, Inc. | Method and apparatus for connective tissue treatment |
US20020016557A1 (en) * | 1997-02-14 | 2002-02-07 | Duarte Luiz R. | Ultrasonic treatment for wounds |
US8480585B2 (en) | 1997-10-14 | 2013-07-09 | Guided Therapy Systems, Llc | Imaging, therapy and temperature monitoring ultrasonic system and method |
US9272162B2 (en) | 1997-10-14 | 2016-03-01 | Guided Therapy Systems, Llc | Imaging, therapy, and temperature monitoring ultrasonic method |
US20060184071A1 (en) * | 1997-12-29 | 2006-08-17 | Julia Therapeutics, Llc | Treatment of skin with acoustic energy |
US20080027328A1 (en) * | 1997-12-29 | 2008-01-31 | Julia Therapeutics, Llc | Multi-focal treatment of skin with acoustic energy |
US20050131359A1 (en) * | 2000-08-24 | 2005-06-16 | Redding Bruce K.Jr. | Substance delivery system |
US7440798B2 (en) | 2000-08-24 | 2008-10-21 | Redding Jr Bruce K | Substance delivery system |
US20050038377A1 (en) * | 2000-08-24 | 2005-02-17 | Redding Bruce K. | Ultrasonically enhanced substance delivery system and device |
US9907535B2 (en) | 2000-12-28 | 2018-03-06 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US8409097B2 (en) | 2000-12-28 | 2013-04-02 | Ardent Sound, Inc | Visual imaging system for ultrasonic probe |
US8235919B2 (en) | 2001-01-12 | 2012-08-07 | Celleration, Inc. | Ultrasonic method and device for wound treatment |
US7819918B2 (en) * | 2001-07-16 | 2010-10-26 | Depuy Products, Inc. | Implantable tissue repair device |
US20050075599A1 (en) * | 2001-08-24 | 2005-04-07 | Redding Bruce K. | Ultrasonically enhanced saline treatment for burn damaged skin |
US20060015059A1 (en) * | 2002-01-16 | 2006-01-19 | Redding Bruce K Jr | Substance delivery device |
US20070012797A1 (en) * | 2003-06-18 | 2007-01-18 | Abb Patent Gmbh | Standing ultrasonic wave spraying arrangement |
US7472850B2 (en) | 2003-06-18 | 2009-01-06 | Abb Patent Gmbh | Ultrasonic standing-wave atomizer arrangement |
WO2004110649A1 (en) * | 2003-06-18 | 2004-12-23 | Abb Patent Gmbh | Standing ultrasonic wave spraying arrangement |
US8235909B2 (en) | 2004-05-12 | 2012-08-07 | Guided Therapy Systems, L.L.C. | Method and system for controlled scanning, imaging and/or therapy |
AU2005205820B2 (en) * | 2004-09-04 | 2011-04-14 | Smith & Nephew Plc | Ultrasound device and method of use |
US10039938B2 (en) | 2004-09-16 | 2018-08-07 | Guided Therapy Systems, Llc | System and method for variable depth ultrasound treatment |
US8708935B2 (en) | 2004-09-16 | 2014-04-29 | Guided Therapy Systems, Llc | System and method for variable depth ultrasound treatment |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US9114247B2 (en) | 2004-09-16 | 2015-08-25 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment with a multi-directional transducer |
US11590370B2 (en) | 2004-09-24 | 2023-02-28 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US9895560B2 (en) | 2004-09-24 | 2018-02-20 | Guided Therapy Systems, Llc | Methods for rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US9095697B2 (en) | 2004-09-24 | 2015-08-04 | Guided Therapy Systems, Llc | Methods for preheating tissue for cosmetic treatment of the face and body |
US10328289B2 (en) | 2004-09-24 | 2019-06-25 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US20090005710A1 (en) * | 2004-10-01 | 2009-01-01 | Duplogen, Inc. | Ultrasonic Equipment for Treatment of Osteoarthritis |
US8333700B1 (en) | 2004-10-06 | 2012-12-18 | Guided Therapy Systems, L.L.C. | Methods for treatment of hyperhidrosis |
US8690780B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive tissue tightening for cosmetic effects |
US10610705B2 (en) | 2004-10-06 | 2020-04-07 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US10610706B2 (en) | 2004-10-06 | 2020-04-07 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US10603519B2 (en) | 2004-10-06 | 2020-03-31 | Guided Therapy Systems, Llc | Energy based fat reduction |
US10888717B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, Llc | Probe for ultrasound tissue treatment |
US10603523B2 (en) | 2004-10-06 | 2020-03-31 | Guided Therapy Systems, Llc | Ultrasound probe for tissue treatment |
US10532230B2 (en) | 2004-10-06 | 2020-01-14 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US10525288B2 (en) | 2004-10-06 | 2020-01-07 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US10888716B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, Llc | Energy based fat reduction |
US10265550B2 (en) | 2004-10-06 | 2019-04-23 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US10252086B2 (en) | 2004-10-06 | 2019-04-09 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US10245450B2 (en) | 2004-10-06 | 2019-04-02 | Guided Therapy Systems, Llc | Ultrasound probe for fat and cellulite reduction |
US10238894B2 (en) | 2004-10-06 | 2019-03-26 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US10960236B2 (en) | 2004-10-06 | 2021-03-30 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US10046182B2 (en) | 2004-10-06 | 2018-08-14 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US11167155B2 (en) | 2004-10-06 | 2021-11-09 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11179580B2 (en) | 2004-10-06 | 2021-11-23 | Guided Therapy Systems, Llc | Energy based fat reduction |
US11207547B2 (en) | 2004-10-06 | 2021-12-28 | Guided Therapy Systems, Llc | Probe for ultrasound tissue treatment |
US8282554B2 (en) | 2004-10-06 | 2012-10-09 | Guided Therapy Systems, Llc | Methods for treatment of sweat glands |
US9427601B2 (en) | 2004-10-06 | 2016-08-30 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US8366622B2 (en) | 2004-10-06 | 2013-02-05 | Guided Therapy Systems, Llc | Treatment of sub-dermal regions for cosmetic effects |
US9427600B2 (en) | 2004-10-06 | 2016-08-30 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US10046181B2 (en) | 2004-10-06 | 2018-08-14 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US8460193B2 (en) | 2004-10-06 | 2013-06-11 | Guided Therapy Systems Llc | System and method for ultra-high frequency ultrasound treatment |
US11235180B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US8506486B2 (en) | 2004-10-06 | 2013-08-13 | Guided Therapy Systems, Llc | Ultrasound treatment of sub-dermal tissue for cosmetic effects |
US8523775B2 (en) | 2004-10-06 | 2013-09-03 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US8636665B2 (en) | 2004-10-06 | 2014-01-28 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of fat |
US8641622B2 (en) | 2004-10-06 | 2014-02-04 | Guided Therapy Systems, Llc | Method and system for treating photoaged tissue |
US8663112B2 (en) | 2004-10-06 | 2014-03-04 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
US8672848B2 (en) | 2004-10-06 | 2014-03-18 | Guided Therapy Systems, Llc | Method and system for treating cellulite |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
US8690778B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Energy-based tissue tightening |
US10888718B2 (en) | 2004-10-06 | 2021-01-12 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US11338156B2 (en) | 2004-10-06 | 2022-05-24 | Guided Therapy Systems, Llc | Noninvasive tissue tightening system |
US10010725B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, Llc | Ultrasound probe for fat and cellulite reduction |
US10010721B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US10010724B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US10010726B2 (en) | 2004-10-06 | 2018-07-03 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US9974982B2 (en) | 2004-10-06 | 2018-05-22 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US11400319B2 (en) | 2004-10-06 | 2022-08-02 | Guided Therapy Systems, Llc | Methods for lifting skin tissue |
US11697033B2 (en) | 2004-10-06 | 2023-07-11 | Guided Therapy Systems, Llc | Methods for lifting skin tissue |
US8915854B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method for fat and cellulite reduction |
US8915870B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US8915853B2 (en) | 2004-10-06 | 2014-12-23 | Guided Therapy Systems, Llc | Methods for face and neck lifts |
US8920324B2 (en) | 2004-10-06 | 2014-12-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US8932224B2 (en) | 2004-10-06 | 2015-01-13 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US9833640B2 (en) | 2004-10-06 | 2017-12-05 | Guided Therapy Systems, L.L.C. | Method and system for ultrasound treatment of skin |
US11717707B2 (en) | 2004-10-06 | 2023-08-08 | Guided Therapy Systems, Llc | System and method for noninvasive skin tightening |
US9039619B2 (en) | 2004-10-06 | 2015-05-26 | Guided Therapy Systems, L.L.C. | Methods for treating skin laxity |
US9833639B2 (en) | 2004-10-06 | 2017-12-05 | Guided Therapy Systems, L.L.C. | Energy based fat reduction |
US9827450B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | System and method for fat and cellulite reduction |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US9713731B2 (en) | 2004-10-06 | 2017-07-25 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9421029B2 (en) | 2004-10-06 | 2016-08-23 | Guided Therapy Systems, Llc | Energy based hyperhidrosis treatment |
US9707412B2 (en) | 2004-10-06 | 2017-07-18 | Guided Therapy Systems, Llc | System and method for fat and cellulite reduction |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9700340B2 (en) | 2004-10-06 | 2017-07-11 | Guided Therapy Systems, Llc | System and method for ultra-high frequency ultrasound treatment |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US9694211B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US9533175B2 (en) | 2004-10-06 | 2017-01-03 | Guided Therapy Systems, Llc | Energy based fat reduction |
US20060089632A1 (en) * | 2004-10-06 | 2006-04-27 | Guided Therapy Systems, L.L.C. | Method and system for treating acne and sebaceous glands |
US9283410B2 (en) | 2004-10-06 | 2016-03-15 | Guided Therapy Systems, L.L.C. | System and method for fat and cellulite reduction |
US9283409B2 (en) | 2004-10-06 | 2016-03-15 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9320537B2 (en) | 2004-10-06 | 2016-04-26 | Guided Therapy Systems, Llc | Methods for noninvasive skin tightening |
US9522290B2 (en) | 2004-10-06 | 2016-12-20 | Guided Therapy Systems, Llc | System and method for fat and cellulite reduction |
US9440096B2 (en) | 2004-10-06 | 2016-09-13 | Guided Therapy Systems, Llc | Method and system for treating stretch marks |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US8166332B2 (en) | 2005-04-25 | 2012-04-24 | Ardent Sound, Inc. | Treatment system for enhancing safety of computer peripheral for use with medical devices by isolating host AC power |
US8868958B2 (en) | 2005-04-25 | 2014-10-21 | Ardent Sound, Inc | Method and system for enhancing computer peripheral safety |
US20080095920A1 (en) * | 2005-08-04 | 2008-04-24 | Eilaz Babaev | Ultrasound medical device coating method |
US20080146970A1 (en) * | 2005-12-06 | 2008-06-19 | Julia Therapeutics, Llc | Gel dispensers for treatment of skin with acoustic energy |
WO2007084792A3 (en) * | 2006-01-23 | 2007-12-13 | Kci Licensing Inc | System and method for treating a wound using ultrasonic debribement |
US8075503B2 (en) | 2006-01-23 | 2011-12-13 | Kci Licensing, Inc. | System and method for treating a wound using ultrasonic debridement |
CN101360473B (en) * | 2006-01-23 | 2011-12-14 | 凯希特许有限公司 | System for treating a wound using ultrasonic debribement |
AU2007206054B2 (en) * | 2006-01-23 | 2011-06-09 | 3M Innovative Properties Company | System and method for treating a wound using ultrasonic debridement |
KR101117394B1 (en) * | 2006-01-23 | 2012-03-07 | 케이씨아이 라이센싱 인코포레이티드 | System for treating a wound using ultrasonic debridement |
US7943352B2 (en) | 2006-03-29 | 2011-05-17 | Bacoustics, Llc | Apparatus and methods for vaccine development using ultrasound technology |
US7842249B2 (en) | 2006-03-29 | 2010-11-30 | Bacoustics, Llc | Apparatus for vaccine development using ultrasound technology |
WO2008024532A1 (en) * | 2006-08-21 | 2008-02-28 | Boston Scientific Scimed, Inc. | Ultrasound catheter |
US20080097316A1 (en) * | 2006-08-21 | 2008-04-24 | Leonid Malinin | Ultrasound catheter |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
EP3056246A1 (en) * | 2006-09-18 | 2016-08-17 | Guided Therapy Systems, L.L.C. | System for non-ablative acne treatment and prevention |
US20080294073A1 (en) * | 2006-09-18 | 2008-11-27 | Guided Therapy Systems, Inc. | Method and sysem for non-ablative acne treatment and prevention |
WO2008036622A3 (en) * | 2006-09-18 | 2008-05-22 | Guided Therapy Systems Llc | Method and system for non-ablative acne treatment and prevention |
US8050752B2 (en) * | 2006-09-29 | 2011-11-01 | Bacoustics, Llc | Method of treating lumens, cavities, and tissues of the body with an ultrasound delivered liquid |
US20080119779A1 (en) * | 2006-09-29 | 2008-05-22 | Eilaz Babaev | Method of Treating Lumens, Cavities, and Tissues of the Body with an Ultrasound Delivered Liquid. |
US9241683B2 (en) | 2006-10-04 | 2016-01-26 | Ardent Sound Inc. | Ultrasound system and method for imaging and/or measuring displacement of moving tissue and fluid |
US7846341B2 (en) | 2006-12-04 | 2010-12-07 | Bacoustics, Llc | Method of ultrasonically treating a continuous flow of fluid |
US20080128362A1 (en) * | 2006-12-04 | 2008-06-05 | Bacoustics Llc | Method of ultrasonically treating a continuous flow of fluid |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
US20150231416A1 (en) * | 2006-12-19 | 2015-08-20 | Board Of Regents Of The University Of Texas System | Ultrasonic bath to increase tissue perfusion |
US20100063423A1 (en) * | 2006-12-19 | 2010-03-11 | Cedars-Sinai Medical Center | Ultrasonic bath to increase tissue perfusion |
US9050448B2 (en) * | 2006-12-19 | 2015-06-09 | Cedars-Sinai Medical Center | Ultrasonic bath to increase tissue perfusion |
US8491521B2 (en) * | 2007-01-04 | 2013-07-23 | Celleration, Inc. | Removable multi-channel applicator nozzle |
US20080243047A1 (en) * | 2007-03-27 | 2008-10-02 | Babaev Eilaz P | Ultrasound wound care device |
US8764687B2 (en) | 2007-05-07 | 2014-07-01 | Guided Therapy Systems, Llc | Methods and systems for coupling and focusing acoustic energy using a coupler member |
US9216276B2 (en) | 2007-05-07 | 2015-12-22 | Guided Therapy Systems, Llc | Methods and systems for modulating medicants using acoustic energy |
US11717661B2 (en) | 2007-05-07 | 2023-08-08 | Guided Therapy Systems, Llc | Methods and systems for ultrasound assisted delivery of a medicant to tissue |
WO2008151277A1 (en) * | 2007-06-05 | 2008-12-11 | Julia Therapeutics, Llc | Gel dispensers for treatment of skin with acoustic energy |
US20090099485A1 (en) * | 2007-10-16 | 2009-04-16 | Sarvazyan Armen P | Ultrasound standing wave method and apparatus for tissue treatment |
US8016208B2 (en) | 2008-02-08 | 2011-09-13 | Bacoustics, Llc | Echoing ultrasound atomization and mixing system |
US7950594B2 (en) | 2008-02-11 | 2011-05-31 | Bacoustics, Llc | Mechanical and ultrasound atomization and mixing system |
US7830070B2 (en) | 2008-02-12 | 2010-11-09 | Bacoustics, Llc | Ultrasound atomization system |
US20090200390A1 (en) * | 2008-02-12 | 2009-08-13 | Eilaz Babaev | Ultrasound atomization system |
US11723622B2 (en) | 2008-06-06 | 2023-08-15 | Ulthera, Inc. | Systems for ultrasound treatment |
US11123039B2 (en) | 2008-06-06 | 2021-09-21 | Ulthera, Inc. | System and method for ultrasound treatment |
US10537304B2 (en) | 2008-06-06 | 2020-01-21 | Ulthera, Inc. | Hand wand for ultrasonic cosmetic treatment and imaging |
US20090312693A1 (en) * | 2008-06-13 | 2009-12-17 | Vytronus, Inc. | System and method for delivering energy to tissue |
US20090312673A1 (en) * | 2008-06-14 | 2009-12-17 | Vytronus, Inc. | System and method for delivering energy to tissue |
WO2010067239A3 (en) * | 2008-12-11 | 2010-08-05 | Koninklijke Philips Electronics, N.V. | System and method for monitoring nebulization of a medicament |
US20110226235A1 (en) * | 2008-12-11 | 2011-09-22 | Koninklijke Philips Electronics, N.V. | System and method for monitoring nebulization of a medicament |
US9821128B2 (en) | 2008-12-11 | 2017-11-21 | Koninklijke Philips N.V. | System and method for monitoring nebulization of a medicament |
US9039617B2 (en) | 2009-11-24 | 2015-05-26 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US9345910B2 (en) | 2009-11-24 | 2016-05-24 | Guided Therapy Systems Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US9149658B2 (en) | 2010-08-02 | 2015-10-06 | Guided Therapy Systems, Llc | Systems and methods for ultrasound treatment |
US10183182B2 (en) | 2010-08-02 | 2019-01-22 | Guided Therapy Systems, Llc | Methods and systems for treating plantar fascia |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
US8858471B2 (en) | 2011-07-10 | 2014-10-14 | Guided Therapy Systems, Llc | Methods and systems for ultrasound treatment |
US9452302B2 (en) | 2011-07-10 | 2016-09-27 | Guided Therapy Systems, Llc | Systems and methods for accelerating healing of implanted material and/or native tissue |
US9011337B2 (en) | 2011-07-11 | 2015-04-21 | Guided Therapy Systems, Llc | Systems and methods for monitoring and controlling ultrasound power output and stability |
WO2013067041A1 (en) * | 2011-11-01 | 2013-05-10 | Indrani Deo | Dispensing nozzle with an ultrasound activator |
US9565870B2 (en) | 2011-11-01 | 2017-02-14 | Pepsico, Inc. | Dispensing nozzle with an ultrasound activator |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
US9802063B2 (en) | 2012-09-21 | 2017-10-31 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
CN103800955A (en) * | 2012-11-09 | 2014-05-21 | 苏州工业园区职业技术学院 | Ultrasonic wave trauma cleaning equipment |
US10420960B2 (en) | 2013-03-08 | 2019-09-24 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US11517772B2 (en) | 2013-03-08 | 2022-12-06 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
US10561862B2 (en) | 2013-03-15 | 2020-02-18 | Guided Therapy Systems, Llc | Ultrasound treatment device and methods of use |
US11224767B2 (en) | 2013-11-26 | 2022-01-18 | Sanuwave Health, Inc. | Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing |
US11331520B2 (en) | 2013-11-26 | 2022-05-17 | Sanuwave Health, Inc. | Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing |
USD733321S1 (en) | 2014-01-10 | 2015-06-30 | Celleration, Inc. | Ultrasonic treatment device |
USD733319S1 (en) | 2014-01-10 | 2015-06-30 | Celleration, Inc. | Ultrasonic treatment wand |
US11351401B2 (en) | 2014-04-18 | 2022-06-07 | Ulthera, Inc. | Band transducer ultrasound therapy |
US10603521B2 (en) | 2014-04-18 | 2020-03-31 | Ulthera, Inc. | Band transducer ultrasound therapy |
CN104027894A (en) * | 2014-06-17 | 2014-09-10 | 南京航空航天大学 | Method for improving infiltration capacity of thrombolytic drug at thrombus part |
US11224895B2 (en) | 2016-01-18 | 2022-01-18 | Ulthera, Inc. | Compact ultrasound device having annular ultrasound array peripherally electrically connected to flexible printed circuit board and method of assembly thereof |
US11241218B2 (en) | 2016-08-16 | 2022-02-08 | Ulthera, Inc. | Systems and methods for cosmetic ultrasound treatment of skin |
US9744315B1 (en) * | 2016-11-28 | 2017-08-29 | Heat In A Click LLC | Skin treatment apparatus |
US11944849B2 (en) | 2018-02-20 | 2024-04-02 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
CN109567760A (en) * | 2019-01-25 | 2019-04-05 | 高密市人民医院 | A kind of care device for the monitoring processing of hand wound |
CN113798110A (en) * | 2021-10-25 | 2021-12-17 | 方翠仙 | Ultrasonic spraying equipment for automobile glass waterproof film |
CN114224620A (en) * | 2021-12-21 | 2022-03-25 | 田艳春 | Debridement nursing device in operating room nursing |
CN114618736A (en) * | 2022-01-26 | 2022-06-14 | 北京航空航天大学 | Ultrasonic spraying device and ultrasonic spraying system |
US11969609B2 (en) | 2022-12-05 | 2024-04-30 | Ulthera, Inc. | Devices and methods for multi-focus ultrasound therapy |
Also Published As
Publication number | Publication date |
---|---|
US20020190136A1 (en) | 2002-12-19 |
US6478754B1 (en) | 2002-11-12 |
US6663554B2 (en) | 2003-12-16 |
WO2002085456A1 (en) | 2002-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6478754B1 (en) | Ultrasonic method and device for wound treatment | |
US6569099B1 (en) | Ultrasonic method and device for wound treatment | |
US7914470B2 (en) | Ultrasonic method and device for wound treatment | |
US8235919B2 (en) | Ultrasonic method and device for wound treatment | |
US6533803B2 (en) | Wound treatment method and device with combination of ultrasound and laser energy | |
US6761729B2 (en) | Wound treatment method and device with combination of ultrasound and laser energy | |
US6960173B2 (en) | Ultrasound wound treatment method and device using standing waves | |
US7713218B2 (en) | Removable applicator nozzle for ultrasound wound therapy device | |
US6964647B1 (en) | Nozzle for ultrasound wound treatment | |
US20070219481A1 (en) | Apparatus and methods for the treatment of avian influenza with ultrasound | |
US20070088217A1 (en) | Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy | |
EP1322275B1 (en) | Ultrasonic method and device for wound treatment | |
US20100324481A1 (en) | Ultrasound pumping apparatus for use with the human body |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: ADVANCED MEDICAL APPLICATIONS, INC., MINNESOTA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BABAEV, EILAZ;REEL/FRAME:012412/0112 Effective date: 20011031 |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |
|
AS | Assignment |
Owner name: TRANSAMERICA TECHNOLOGY FINANCE CORPORATION, CONNE Free format text: SECURITY INTEREST;ASSIGNOR:CELLERATION, INC.;REEL/FRAME:013907/0846 Effective date: 20030327 |
|
FEPP | Fee payment procedure |
Free format text: PAYOR NUMBER ASSIGNED (ORIGINAL EVENT CODE: ASPN); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY Free format text: PAT HOLDER CLAIMS SMALL ENTITY STATUS, ENTITY STATUS SET TO SMALL (ORIGINAL EVENT CODE: LTOS); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY |
|
FPAY | Fee payment |
Year of fee payment: 4 |
|
AS | Assignment |
Owner name: CELLERATION, INC., MINNESOTA Free format text: CHANGE OF NAME;ASSIGNOR:ADVANCED MEDICAL APPLICATIONS, INC.;REEL/FRAME:019102/0655 Effective date: 20020730 Owner name: CELLERATION, INC., MINNESOTA Free format text: MERGER;ASSIGNOR:CELLERATION, INC.;REEL/FRAME:019094/0591 Effective date: 20030506 |
|
AS | Assignment |
Owner name: CELLERATION, INC., MINNESOTA Free format text: RELEASE BY SECURED PARTY;ASSIGNOR:GE TECHNOLOGY FINANCE CORPORATION;REEL/FRAME:021561/0802 Effective date: 20080905 |
|
FEPP | Fee payment procedure |
Free format text: PAYOR NUMBER ASSIGNED (ORIGINAL EVENT CODE: ASPN); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY Free format text: PAYER NUMBER DE-ASSIGNED (ORIGINAL EVENT CODE: RMPN); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY |
|
FPAY | Fee payment |
Year of fee payment: 8 |
|
FPAY | Fee payment |
Year of fee payment: 12 |
|
AS | Assignment |
Owner name: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP C/O PERCEPTIVE ADVISORS LLC, NEW YORK Free format text: SECURITY INTEREST;ASSIGNOR:ALQA CEDAR, INC.;REEL/FRAME:035745/0313 Effective date: 20150529 Owner name: PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP C/O PERCE Free format text: SECURITY INTEREST;ASSIGNOR:ALQA CEDAR, INC.;REEL/FRAME:035745/0313 Effective date: 20150529 |
|
AS | Assignment |
Owner name: ALLIQUA BIOMEDICAL, INC., PENNSYLVANIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CELLERATION, INC.;REEL/FRAME:036140/0913 Effective date: 20150721 |
|
AS | Assignment |
Owner name: ALLIQUA BIOMEDICAL, INC., PENNSYLVANIA Free format text: CHANGE OF ASSIGNEE ADDRESS;ASSIGNOR:CELLERATION, INC.;REEL/FRAME:038274/0778 Effective date: 20150721 |
|
AS | Assignment |
Owner name: ALQA CEDAR, INC., PENNSYLVANIA Free format text: RELEASE BY SECURED PARTY;ASSIGNOR:PERCEPTIVE CREDIT OPPORTUNITIES FUND, LP C/O PERCEPTIVE ADVISORS LLC;REEL/FRAME:045756/0204 Effective date: 20180507 |
|
AS | Assignment |
Owner name: CELULARITY INC., NEW JERSEY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ALLIQUA BIOMEDICAL, INC.;REEL/FRAME:053152/0144 Effective date: 20180507 |
|
AS | Assignment |
Owner name: NH EXPANSION CREDIT FUND HOLDINGS LP, NEW YORK Free format text: SECURITY INTEREST;ASSIGNOR:SANUWAVE HEALTH, INC.;REEL/FRAME:053435/0842 Effective date: 20200806 |
|
AS | Assignment |
Owner name: SANUWAVE HEALTH, INC., GEORGIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CELULARITY INC.;REEL/FRAME:054299/0846 Effective date: 20200806 |