US20040260236A1 - Guide catheter steering using pre-shaped rotatable shaft - Google Patents
Guide catheter steering using pre-shaped rotatable shaft Download PDFInfo
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- US20040260236A1 US20040260236A1 US10/890,875 US89087504A US2004260236A1 US 20040260236 A1 US20040260236 A1 US 20040260236A1 US 89087504 A US89087504 A US 89087504A US 2004260236 A1 US2004260236 A1 US 2004260236A1
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- sheath
- distal end
- outer sheath
- inner sheath
- open lumen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0147—Tip steering devices with movable mechanical means, e.g. pull wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
- A61B5/283—Invasive
- A61B5/287—Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0152—Tip steering devices with pre-shaped mechanisms, e.g. pre-shaped stylets or pre-shaped outer tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M2025/0161—Tip steering devices wherein the distal tips have two or more deflection regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0041—Catheters; Hollow probes characterised by the form of the tubing pre-formed, e.g. specially adapted to fit with the anatomy of body channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
- A61N1/057—Anchoring means; Means for fixing the head inside the heart
- A61N2001/0578—Anchoring means; Means for fixing the head inside the heart having means for removal or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/056—Transvascular endocardial electrode systems
- A61N2001/0585—Coronary sinus electrodes
Definitions
- the invention relates generally to methods of guiding catheters, and, more particularly, to methods involving dual-sheath, telescoping guide catheters having a steerable outer sheath and pre-formed inner sheath used to locate and cannulate the coronary sinus of a patient's heart.
- Guiding catheters are instruments that allow a physician to locate and cannulate vessels in a patient's heart for preforming various medical procedures, including venography and implanting of cardiac pacing devices.
- Cannulating heart vessels requires navigating a small diameter, flexible guide through the convoluted vasculature into a heart chamber, and then into a destination heart vessel. Once the destination heart vessel is reached, the catheter acts as a conduit for insertion of payloads into the vessel.
- a commonly accessed destination vessel for cardiac pacing lead insertion is the coronary sinus.
- a pre-shaped guiding catheter is typically used to blindly locate the coronary sinus ostium. This endeavor, however, is complicated by the fact that the location of the coronary sinus ostium may vary appreciably from one patient to another, especially among patients with diseased hearts.
- the clinician is entirely unable to locate the coronary sinus ostium using the guiding catheter, and must resort to finding the ostium by “mapping” (interpreting localized bipolar waveforms) using an electrophysiological (EP) catheter and an ECG monitor.
- the guiding catheter is typically used to inject radiographic contrast media into the coronary sinus to highlight the associated venous system, and then a pacing lead is installed within one of the coronary branches.
- Guiding catheter systems are typically configured with a profile that is optimized for the intended method of access.
- a catheter with a distal contour including a relatively sharp bend will point the catheter towards the likely location of the coronary sinus once the right atrium is reached.
- the contours of pre-shaped guiding catheters are generally fixed, and this is typically achieved in production by constraining the distal end within a shaping fixture while warming them until they assume the intended shape (i.e., by “heat setting” their polymer shaft).
- a fixed shape catheter is adequate in many cases where the pathway is not significantly convoluted and the pathway does not deviate significantly between patients. In situations where structural anomalies or significant variations exist, use of a fixed shape catheter may require that the clinician stock multiple size and shapes of catheters to account for potential variations. Fixed shape catheters may require a time consuming trial and error process of inserting and removing different shapes until the destination vessel is successfully accessed.
- a method involves providing a guide catheter that includes an outer sheath having an open lumen and a pre-shaped distal end, and an inner sheath having an open lumen and a distal end provided with a pre-formed shape.
- the inner sheath is disposed within the open lumen of the outer sheath.
- the distal end of the inner sheath conforms to a shape of the outer sheath when the inner sheath is retracted within the outer sheath.
- a steering tendon is disposed along the outer sheath, a distal end of which is connected to a distal tip of the outer sheath.
- a guide handle is connected to a proximal end of the outer sheath, and a steering mechanism is disposed on the guide handle. The steering mechanism is connected to a proximal end of the steering tendon.
- the method further involves axially rotating and longitudinally translating the inner sheath relative to the outer sheath, whereby the distal end of the inner sheath assumes its pre-formed shape when the distal end of the inner sheath is extended beyond the distal end of the outer sheath.
- a pulling force provided on the steering tendon adjustably changes a shape of the pre-shaped distal end of the outer sheath.
- the method may further involve advancing a payload through the open lumen of the inner sheath.
- the payload may include a pacing lead, a guidewire, or a combination of guidewire and pacing lead through the open lumen of the inner sheath.
- the method may also involve injecting a contrast media for venography into the open lumen of the inner sheath.
- a method according to an embodiment of the present invention may involve proximally retracting the inner sheath to remove the inner sheath from the outer sheath, and advancing a payload through the open lumen of the outer sheath.
- the inner sheath may be proximally retracted to remove the inner sheath from the outer sheath, and a pacing lead may be advanced through the open lumen of the outer sheath.
- the outer sheath of the guide catheter may incorporate at least one pre-stress line extending from the proximal end to a distal tip of the outer sheath.
- a method of the present invention may involve splitting the outer sheath while retracting the outer sheath in a proximal direction.
- energy may be delivered from the distal end of at least one of the inner and outer sheaths sufficient to ablate cardiac tissue.
- cardiac tissue may be subject to mapping by use of one or more electrodes provided at the distal end of at least one of the inner and outer sheaths.
- Methods of the present invention may further involve sensing one or more of pressure, acceleration, blood flow, or blood velocity at the distal end of at least one of the inner and outer sheaths. Methods of the present invention may also involve sensing one or both of temperature or oxygen saturation at the distal end of at least one of the inner and outer sheaths. Various embodiments may involve occluding blood flow proximate the distal end of at least one of the inner and outer sheaths.
- a method of the present invention involves providing a guide catheter of a type previously described.
- the method may involve inserting a distal end of the catheter into a patient's right atrium via an access vessel and distally extending the inner sheath from the outer sheath.
- the distal end of the inner sheath assumes a pre-formed shape upon extending beyond the distal end of the outer sheath.
- the method may further involve providing a pulling force on the steering tendon to modify an angle of the pre-shaped distal end of the outer sheath, axially rotating the inner sheath relative to the outer sheath, and longitudinally translating the inner sheath relative to the outer sheath to direct the distal end of the inner sheath for finding and cannulating the patient's coronary sinus.
- the method may also involve advancing a payload, such as a pacing lead and/or a guidewire, through the open lumen of the inner sheath to insert the payload into the coronary sinus.
- Methods may also involve proximally retracting the inner sheath to remove the inner sheath from the outer sheath after cannulating the patient's coronary sinus, and advancing a payload, such as a pacing lead, through the open lumen of the outer sheath.
- Methods according to this embodiment may further involve processes described above.
- FIG. 1 is an external view of a catheter embodying features of the present invention and illustrating longitudinal translation of an inner sheath relative to an outer sheath;
- FIG. 2 is an external view of the catheter shown in FIG. 1 illustrating the inner sheath rotating within the outer sheath;
- FIG. 3A is an external view of the catheter shown in FIG. 1 further illustrating a deflection of a pre-shaped distal end of the outer sheath
- FIG. 3B is cross section view of Section 1 - 1 from FIG. 3A;
- FIG. 4 is a cut-away view of a patient's heart, showing a catheter embodying features of the present invention deployed within the heart;
- FIG. 5 is an external view of a catheter illustrating a peel-away outer sheath according to an embodiment of the present invention
- FIG. 6 is an external view of a catheter containing a pacing lead within the outer sheath according to an embodiment of the present invention
- FIG. 7 is a view of the distal end of a catheter showing an occlusion balloon attached to the inner sheath according to an embodiment of the present invention.
- FIG. 8 is view of the distal end of a catheter illustrating electrodes on the distal tip of the inner sheath according to an embodiment of the present invention.
- the guide catheter includes an inner sheath 1 , an outer sheath 2 , and a guide handle 3 .
- the guide handle 3 is connected to a proximal end of the outer sheath 2 .
- the guide handle 3 can include a homeostasis device that provides a seal between the inner and outer sheaths 1 , 2 .
- the outer sheath 2 contains an open lumen 2 A, and the outer sheath 2 is typically elongated and flexible.
- the outer sheath 2 is also adjustably deflectable at a distal end.
- the inner sheath 1 is movably disposed within the open lumen 2 A of the outer sheath 2 such that the inner sheath 1 can translate longitudinally and rotate axially within the outer sheath 2 .
- the inner sheath 1 is typically more flexible than the outer sheath and includes a pre-formed distal shape 4 .
- the more flexible inner sheath 1 conforms to the shape of the outer sheath 2 when a substantial portion of the inner sheath's distal end is contained within the outer sheath 2 .
- the distal end of the inner sheath 1 assumes its pre-formed distal shape 4 , as indicated by phantom lines in FIG. 1.
- the inner sheath 1 can be formed of a polymeric tube.
- Pebax is a polymer typically used in this application, although other materials such as nylon and PVC may be employed. Constructing the inner sheath 1 from a multi-layered tube having a metallic braid may be desirable in some applications where greater stiffness is required.
- the pre-formed distal shape 4 can be thermoset during manufacture of the inner sheath 1 .
- the inner sheath 1 has an open lumen 1 A that can receive a payload.
- An inner lubricous lining made of a material such as PTFE can be provided within the open lumen 1 A.
- the lubricious liner helps to ease advancement of payloads through the open lumen 1 A.
- An inner sheath 1 used in coronary sinus cannulation procedures may have an inner lumen diameter of about 0.030 inches to about 0.100 inches, depending on the size of payloads and/or guide members that are intended to pass through or otherwise be disposed within the open lumen 1 A.
- the ability of the inner sheath 1 to assume a pre-formed distal shape 4 upon inner sheath extension is advantageous for accessing vessels within a patient's heart.
- a commonly traversed pathway is through a percutaneous access vessel such as the left subclavian, then through the superior vena cava and into the right atrium of the heart.
- This pathway is a relatively large, smooth curve, and outer sheath 2 can be shaped to accommodate the pathway.
- the inner sheath 1 can be retracted within the outer sheath 2 while the guide catheter is being advanced through the pathway, allowing the guide catheter to substantially assume the shape of the outer sheath 2 .
- the inner sheath 1 can now be extended to provide such a transition. Extension of the inner sheath 1 past the distal tip of the outer sheath 2 allows the distal end of the inner sheath 1 to assume its pre-formed distal shape 4 .
- the pre-formed distal shape 4 can have dimensions that are optimized for locating the coronary sinus ostium, in this example. Axial rotation and longitudinal extension of the inner sheath 1 within the outer sheath 2 beneficially allows the distal end of the inner sheath 1 to account for variations within the right atrium while searching for the ostium.
- FIG. 2 illustrates the maneuverability provided by the rotatable inner sheath 1 .
- the inner sheath 1 is axially rotatable within the outer sheath 2 .
- Rotation of the inner sheath 1 is typically performed by grasping a proximal section of the inner sheath 1 and applying a torque to the inner sheath 1 while restraining the outer sheath 2 .
- an attachment may be provided on the proximal end of the inner sheath 1 , such as a wing luer 5 , shown in FIG. 2.
- the curved arrows in FIG. 2 show the effect on the distal end of the inner sheath 1 caused by rotating the wing luer 5 .
- Phantom lines at the distal end of the inner sheath 1 illustrate various rotated orientations of the inner sheath 1 .
- the outer sheath 2 is adjustably deflectable.
- the guide catheter includes a steering tendon 7 disposed within the outer sheath 2 .
- the steering tendon 7 is attached to the distal end of the outer sheath 2 , as shown in the detail drawing of FIG. 3A.
- the steering tendon 7 is attached by bonding or embedding a semicircular plate 8 near the outer sheath distal tip.
- the steering tendon 7 is fixably attached to the semicircular plate 8 . Applying a tensile force on the proximal end of the steering tendon 7 changes a shape of the deflects the distal tip of the outer sheath 2 .
- a steering handle 6 may be attached to the guide handle 3 to enable adjustably applying a tensile force to the steering tendon 7 .
- the steering handle 6 is typically pivotably mounted on the guide handle 3 , and may include a friction or lock mechanism to hold the steering handle 6 at a fixed position.
- the outer sheath 2 may include a pre-formed distal end 9 .
- the pre-formed distal end 9 can be optimally shaped for advancement through heart chambers or intended venous pathways.
- the pre-formed distal end 9 may also determine the deflection point of the outer sheath 2 upon application of a tensile force to the steering tendon 7 .
- the outer sheath 2 has an initial shape at the pre-formed distal end 9 .
- the direction of motion of the outer sheath 2 as it is deflected by the steering tendon 7 and steering handle 6 is indicated by the bold arrows.
- the deflected positions of the steering handle 6 and outer sheath 2 are indicated in phantom lines.
- the steering tendon 7 affects a bend angle and a bend radius of the preformed distal end 9 , thereby enabling deflection of a distal tip of the guide catheter.
- the outer sheath 2 may be formed of a polymeric tube similar to the inner sheath 1 .
- the outer sheath 2 is typically stiffer than the inner sheath 1 , and may benefit from a multilayer construction that includes a metallic braid or coil.
- An inner lubricous lining made of PTFE or equivalent material can be provided within the outer sheath lumen 2 A to reduce friction between the inner and outer sheaths 1 , 2 .
- the steering tendon 7 can be disposed within the outer sheath lumen 2 A.
- the steering tendon 7 can also be disposed along an outer surface of the outer sheath 2 .
- the outer sheath 2 can contain a second lumen 21 as seen in FIG. 3B.
- the steering tendon 7 is deployed within the second lumen 21 .
- the steering tendon 7 may be formed of a metallic wire or ribbon, although other tensile members such as a high strength polymer fiber can also be employed with similar results.
- a catheter embodying features of the present invention is particularly useful in applications such as implanting pacing and defibrillation leads into heart vessels.
- This procedure is illustrated FIG. 4.
- the distal end of the catheter is typically introduced through a percutaneous access point 10 , such as in the left cephalic vein or left subclavian vein.
- the inner sheath 1 can be retracted within the outer sheath 2 while the catheter is advanced through the access vessel into to the heart.
- the catheter advances through the superior vena cava into the right atrium 11 .
- a guide wire 13 may be inserted through the venous pathway before the catheter is introduced, and the catheter then advanced over the guide wire 13 into the right atrium.
- the inner sheath 1 can be extended.
- the inner sheath 1 is extended and rotated to locate the coronary sinus ostium 12 . Additional assistance in finding the ostium 12 is provided by deflecting the outer sheath 2 via the steering tendon 7 .
- the inner sheath 1 can be advanced as far as required into the coronary sinus.
- the guide wire 13 can be advanced through the inner sheath 1 into the coronary sinus. The guide wire 13 is then distally extended beyond the inner sheath 1 into a branch of the coronary sinus. The guide wire 13 can then be used to guide a pacing lead 14 into the branch vessel. The pacing lead 14 is advanced through the inner sheath 1 and seated into the branch of the coronary sinus.
- a peel away feature may include one or more longitudinal pre-stress lines 15 extending from proximal to distal ends along the outer sheath 2 .
- the advantages of a peel-away feature include the ability to proximally remove the outer sheath 2 over the inner sheath 1 seated without disturbing any proximal attachments on the inner sheath 1 .
- Proximal attachments on the inner sheath 1 may include a wing luer 5 .
- a peel-away feature of the outer sheath 2 in a catheter according the present invention can further include the ability of the guide handle 3 to separate into at least two sections. As seen in FIG. 5, application of forces to the separation grips 16 can split the guide handle 3 .
- the guide handle 3 is connected to the outer sheath 2 , so guide handle separation can initiate outer sheath separation as well. Further details of exemplary peel-away features are disclosed in commonly owned U.S. application serial no. 10/036,640, filed Dec. 31, 2001 and entitled “Telescoping Guide Catheter With Peel-Away Outer Sheath” (Atty. Docket No. GUID.037US01), which is hereby incorporated herein by reference.
- the pacing lead 14 is advanced through the outer sheath 2 .
- This may be desirable as the outer sheath lumen 2 A is larger than that of the inner sheath 1 .
- the outer sheath 2 is distally advanced over the inner sheath 1 until the outer sheath 2 is seated in the coronary sinus.
- the inner sheath 1 is then proximally retracted and removed, whereupon pacing lead insertion can proceed through the outer sheath 2 .
- FIG. 6 This situation is illustrated in FIG. 6, where the pacing lead 14 is shown extending from the distal end of the outer sheath 2 .
- the outer sheath 2 illustrated in FIG. 6 also employs a distally mounted occlusion balloon 15 .
- the occlusion balloon 15 can be inflated when the outer sheath 2 is in a vessel where blockage of blood flow is desired. Blood flow can be temporarily occluded in this way before injecting a contrast media, for example.
- the occlusion balloon 15 is typically inflated by a fluid injected from a proximal end of the outer sheath 2 . Methods of mounting and actuating the occlusion balloon 15 are well known in the art.
- FIG. 7 illustrates an occlusion balloon 16 mounted on the distal end of the inner sheath 1 . Actuation and disposition of the occlusion balloon 16 is similar to that described for the occlusion balloon 15 mounted on the outer sheath 2 .
- FIG. 7 shows electrodes 17 mounted on the distal end of the outer sheath 2 .
- the electrodes 17 are typically flush mounted, and are connected to at least one conductor 18 that is disposed between the distal and proximal ends of the inner sheath 1 .
- FIG. 8 shows electrodes 19 mounted on the inner sheath 1 in a similar fashion as the electrodes 17 on the outer sheath 2 .
- the electrodes 19 are connected to at least one conductor 20 that is disposed within the inner sheath 1 . It is understood the electrodes may be disposed on both the inner and outer sheaths 1 , 2 in certain configurations.
- the electrodes 17 , 19 can be used for electrophysiological (EP) purposes, such as EP mapping structures within the heart.
- EP electrodes are often fabricated from stainless steel, although the electrodes 17 , 19 could be made of platinum, silver or other electrode materials known in the art.
- a guide catheter according to the present invention can also be adapted to use ablation electrodes.
- Ablation electrodes are typically formed of platinum/iridium, and can be mounted as previously described and illustrated in FIGS. 7 and 8.
- a pressure sensor for example, can detect dynamic characteristics of blood flow, including fluid velocity.
- Tubular piezoelectric sensors can be configured to sense pressure on the inner sheath 1 , and can be deployed in a similar manner to the electrodes 19 shown in FIG. 8. As with the electrodes 19 , at least one conductor 20 would be coupled to the pressure sensing device and disposed within the inner or outer sheath 1 , 2 .
- Other sensors that can be similarly incorporated on the inner and outer sheaths 1 , 2 include a temperature sensor, activity sensor (e.g. accelerometer) or oxygen sensor.
Abstract
Methods involving guide catheters include providing a guide catheter that has an outer sheath having an open lumen and a pre-shaped distal end, and an inner sheath having an open lumen and a distal end provided with a pre-formed shape. A steering tendon is disposed along the outer sheath, a distal end of which is connected to the outer sheath's distal tip. A steering mechanism is connected to a proximal end of the steering tendon and includes a guide handle. The inner sheath is rotated and longitudinally translated relative to the outer sheath, whereby the distal end of the inner sheath assumes its pre-formed shape when the inner sheath's distal end extends beyond the outer sheath's distal end. A pulling force applied to the steering tendon adjustably changes a shape of the outer sheath's pre-shaped distal end. A payload may be advanced through the inner sheath's open lumen.
Description
- This application is a divisional of U.S. patent application Ser. No. 10/041,911, filed on Jan. 7, 2002, to which priority is claimed under 35 U.S.C. § 120, and which is incorporated herein by reference.
- The invention relates generally to methods of guiding catheters, and, more particularly, to methods involving dual-sheath, telescoping guide catheters having a steerable outer sheath and pre-formed inner sheath used to locate and cannulate the coronary sinus of a patient's heart.
- Guiding catheters are instruments that allow a physician to locate and cannulate vessels in a patient's heart for preforming various medical procedures, including venography and implanting of cardiac pacing devices. Cannulating heart vessels requires navigating a small diameter, flexible guide through the convoluted vasculature into a heart chamber, and then into a destination heart vessel. Once the destination heart vessel is reached, the catheter acts as a conduit for insertion of payloads into the vessel.
- A commonly accessed destination vessel for cardiac pacing lead insertion is the coronary sinus. A pre-shaped guiding catheter is typically used to blindly locate the coronary sinus ostium. This endeavor, however, is complicated by the fact that the location of the coronary sinus ostium may vary appreciably from one patient to another, especially among patients with diseased hearts. Oftentimes, the clinician is entirely unable to locate the coronary sinus ostium using the guiding catheter, and must resort to finding the ostium by “mapping” (interpreting localized bipolar waveforms) using an electrophysiological (EP) catheter and an ECG monitor. After the ostium is located, the guiding catheter is typically used to inject radiographic contrast media into the coronary sinus to highlight the associated venous system, and then a pacing lead is installed within one of the coronary branches.
- Complicating this scenario is the dynamic structural deformation of the heart chambers that occurs from normal cardiac activity during the procedure. This further increases the difficulty of guiding a catheter to its destination. Presently, a considerable amount of time is often spent by the physician when manipulating such catheters within cardiac structures, such as the right atrium, simply trying to locate an anatomical feature of interest, such as the coronary sinus ostium.
- Guiding catheter systems are typically configured with a profile that is optimized for the intended method of access. In the case of accessing the coronary sinus via the right atrium, a catheter with a distal contour including a relatively sharp bend will point the catheter towards the likely location of the coronary sinus once the right atrium is reached. The contours of pre-shaped guiding catheters are generally fixed, and this is typically achieved in production by constraining the distal end within a shaping fixture while warming them until they assume the intended shape (i.e., by “heat setting” their polymer shaft).
- A fixed shape catheter is adequate in many cases where the pathway is not significantly convoluted and the pathway does not deviate significantly between patients. In situations where structural anomalies or significant variations exist, use of a fixed shape catheter may require that the clinician stock multiple size and shapes of catheters to account for potential variations. Fixed shape catheters may require a time consuming trial and error process of inserting and removing different shapes until the destination vessel is successfully accessed.
- There is a need for an improved guide catheter for accessing heart vessels that can dynamically account for anatomical variations and defects associated with the destination structures. The present invention fulfills these and other needs, and addresses other deficiencies of prior art implementations and techniques.
- The present invention is directed to methods involving guide catheters, including locating and cannulating vessels of the heart. A method according to one embodiment involves providing a guide catheter that includes an outer sheath having an open lumen and a pre-shaped distal end, and an inner sheath having an open lumen and a distal end provided with a pre-formed shape. The inner sheath is disposed within the open lumen of the outer sheath. The distal end of the inner sheath conforms to a shape of the outer sheath when the inner sheath is retracted within the outer sheath. A steering tendon is disposed along the outer sheath, a distal end of which is connected to a distal tip of the outer sheath. A guide handle is connected to a proximal end of the outer sheath, and a steering mechanism is disposed on the guide handle. The steering mechanism is connected to a proximal end of the steering tendon.
- The method further involves axially rotating and longitudinally translating the inner sheath relative to the outer sheath, whereby the distal end of the inner sheath assumes its pre-formed shape when the distal end of the inner sheath is extended beyond the distal end of the outer sheath. A pulling force provided on the steering tendon adjustably changes a shape of the pre-shaped distal end of the outer sheath.
- The method may further involve advancing a payload through the open lumen of the inner sheath. The payload may include a pacing lead, a guidewire, or a combination of guidewire and pacing lead through the open lumen of the inner sheath. The method may also involve injecting a contrast media for venography into the open lumen of the inner sheath.
- A method according to an embodiment of the present invention may involve proximally retracting the inner sheath to remove the inner sheath from the outer sheath, and advancing a payload through the open lumen of the outer sheath. For example, the inner sheath may be proximally retracted to remove the inner sheath from the outer sheath, and a pacing lead may be advanced through the open lumen of the outer sheath.
- The outer sheath of the guide catheter may incorporate at least one pre-stress line extending from the proximal end to a distal tip of the outer sheath. A method of the present invention may involve splitting the outer sheath while retracting the outer sheath in a proximal direction.
- In other embodiments, energy may be delivered from the distal end of at least one of the inner and outer sheaths sufficient to ablate cardiac tissue. In other embodiments, cardiac tissue may be subject to mapping by use of one or more electrodes provided at the distal end of at least one of the inner and outer sheaths.
- Methods of the present invention may further involve sensing one or more of pressure, acceleration, blood flow, or blood velocity at the distal end of at least one of the inner and outer sheaths. Methods of the present invention may also involve sensing one or both of temperature or oxygen saturation at the distal end of at least one of the inner and outer sheaths. Various embodiments may involve occluding blood flow proximate the distal end of at least one of the inner and outer sheaths.
- In accordance with another embodiment, a method of the present invention involves providing a guide catheter of a type previously described. The method may involve inserting a distal end of the catheter into a patient's right atrium via an access vessel and distally extending the inner sheath from the outer sheath. The distal end of the inner sheath assumes a pre-formed shape upon extending beyond the distal end of the outer sheath. The method may further involve providing a pulling force on the steering tendon to modify an angle of the pre-shaped distal end of the outer sheath, axially rotating the inner sheath relative to the outer sheath, and longitudinally translating the inner sheath relative to the outer sheath to direct the distal end of the inner sheath for finding and cannulating the patient's coronary sinus.
- The method may also involve advancing a payload, such as a pacing lead and/or a guidewire, through the open lumen of the inner sheath to insert the payload into the coronary sinus. Methods may also involve proximally retracting the inner sheath to remove the inner sheath from the outer sheath after cannulating the patient's coronary sinus, and advancing a payload, such as a pacing lead, through the open lumen of the outer sheath. Methods according to this embodiment may further involve processes described above.
- The above summary of the present invention is not intended to describe each embodiment or every implementation of the present invention. Advantages and attainments, together with a more complete understanding of the invention, will become apparent and appreciated by referring to the following detailed description and claims taken in conjunction with the accompanying drawings.
- FIG. 1 is an external view of a catheter embodying features of the present invention and illustrating longitudinal translation of an inner sheath relative to an outer sheath;
- FIG. 2 is an external view of the catheter shown in FIG. 1 illustrating the inner sheath rotating within the outer sheath;
- FIG. 3A is an external view of the catheter shown in FIG. 1 further illustrating a deflection of a pre-shaped distal end of the outer sheath
- FIG. 3B is cross section view of Section1-1 from FIG. 3A;
- FIG. 4 is a cut-away view of a patient's heart, showing a catheter embodying features of the present invention deployed within the heart;
- FIG. 5 is an external view of a catheter illustrating a peel-away outer sheath according to an embodiment of the present invention;
- FIG. 6 is an external view of a catheter containing a pacing lead within the outer sheath according to an embodiment of the present invention;
- FIG. 7 is a view of the distal end of a catheter showing an occlusion balloon attached to the inner sheath according to an embodiment of the present invention; and
- FIG. 8 is view of the distal end of a catheter illustrating electrodes on the distal tip of the inner sheath according to an embodiment of the present invention.
- While the invention is amenable to various modifications and alternative forms, specifics thereof have been shown by way of example in the drawings and will be described in detail herein. It is to be understood, however, that the intention is not to limit the invention to the particular embodiments described. On the contrary, the invention is intended to cover all modifications, equivalents, and alternatives falling within the scope of the invention as defined by the appended claims.
- In the following description of the illustrated embodiments, references are made to the accompanying drawings which form a part hereof, and in which is shown by way of illustration, various embodiments in which the invention may be practiced. It is to be understood that other embodiments may be utilized, and structural and functional changes may be made without departing from the scope of the present invention.
- With reference to FIG. 1, a guide catheter is shown embodying features of the present invention. The guide catheter includes an
inner sheath 1, anouter sheath 2, and aguide handle 3. The guide handle 3 is connected to a proximal end of theouter sheath 2. The guide handle 3 can include a homeostasis device that provides a seal between the inner andouter sheaths outer sheath 2 contains anopen lumen 2A, and theouter sheath 2 is typically elongated and flexible. Theouter sheath 2 is also adjustably deflectable at a distal end. Theinner sheath 1 is movably disposed within theopen lumen 2A of theouter sheath 2 such that theinner sheath 1 can translate longitudinally and rotate axially within theouter sheath 2. - The
inner sheath 1 is typically more flexible than the outer sheath and includes a pre-formeddistal shape 4. The more flexibleinner sheath 1 conforms to the shape of theouter sheath 2 when a substantial portion of the inner sheath's distal end is contained within theouter sheath 2. When theinner sheath 1 is sufficiently extended, the distal end of theinner sheath 1 assumes its pre-formeddistal shape 4, as indicated by phantom lines in FIG. 1. - The
inner sheath 1 can be formed of a polymeric tube. Pebax is a polymer typically used in this application, although other materials such as nylon and PVC may be employed. Constructing theinner sheath 1 from a multi-layered tube having a metallic braid may be desirable in some applications where greater stiffness is required. The pre-formeddistal shape 4 can be thermoset during manufacture of theinner sheath 1. - The
inner sheath 1 has anopen lumen 1A that can receive a payload. An inner lubricous lining made of a material such as PTFE can be provided within theopen lumen 1A. The lubricious liner helps to ease advancement of payloads through theopen lumen 1A. Aninner sheath 1 used in coronary sinus cannulation procedures may have an inner lumen diameter of about 0.030 inches to about 0.100 inches, depending on the size of payloads and/or guide members that are intended to pass through or otherwise be disposed within theopen lumen 1A. - The ability of the
inner sheath 1 to assume a pre-formeddistal shape 4 upon inner sheath extension is advantageous for accessing vessels within a patient's heart. For example, when accessing the patient's coronary sinus, a commonly traversed pathway is through a percutaneous access vessel such as the left subclavian, then through the superior vena cava and into the right atrium of the heart. This pathway is a relatively large, smooth curve, andouter sheath 2 can be shaped to accommodate the pathway. Theinner sheath 1 can be retracted within theouter sheath 2 while the guide catheter is being advanced through the pathway, allowing the guide catheter to substantially assume the shape of theouter sheath 2. - Once the distal end of the catheter has entered the right atrium, a relatively sharp transition is desirable to access the coronary sinus ostium. The
inner sheath 1 can now be extended to provide such a transition. Extension of theinner sheath 1 past the distal tip of theouter sheath 2 allows the distal end of theinner sheath 1 to assume its pre-formeddistal shape 4. The pre-formeddistal shape 4 can have dimensions that are optimized for locating the coronary sinus ostium, in this example. Axial rotation and longitudinal extension of theinner sheath 1 within theouter sheath 2 beneficially allows the distal end of theinner sheath 1 to account for variations within the right atrium while searching for the ostium. - FIG. 2 illustrates the maneuverability provided by the rotatable
inner sheath 1. Theinner sheath 1 is axially rotatable within theouter sheath 2. Rotation of theinner sheath 1 is typically performed by grasping a proximal section of theinner sheath 1 and applying a torque to theinner sheath 1 while restraining theouter sheath 2. To assist in applying a torque, an attachment may be provided on the proximal end of theinner sheath 1, such as awing luer 5, shown in FIG. 2. The curved arrows in FIG. 2 show the effect on the distal end of theinner sheath 1 caused by rotating thewing luer 5. Phantom lines at the distal end of theinner sheath 1 illustrate various rotated orientations of theinner sheath 1. - To provide further advantages with respect to accessing vessels within a heart chamber, the
outer sheath 2 is adjustably deflectable. Referring to FIG. 3A, the deflectability of theouter sheath 2 is illustrated. The guide catheter includes asteering tendon 7 disposed within theouter sheath 2. Thesteering tendon 7 is attached to the distal end of theouter sheath 2, as shown in the detail drawing of FIG. 3A. In one configuration, thesteering tendon 7 is attached by bonding or embedding asemicircular plate 8 near the outer sheath distal tip. Thesteering tendon 7 is fixably attached to thesemicircular plate 8. Applying a tensile force on the proximal end of thesteering tendon 7 changes a shape of the deflects the distal tip of theouter sheath 2. - A steering handle6 may be attached to the guide handle 3 to enable adjustably applying a tensile force to the
steering tendon 7. The steering handle 6 is typically pivotably mounted on theguide handle 3, and may include a friction or lock mechanism to hold the steering handle 6 at a fixed position. - To aid in the action of the
steering tendon 7, theouter sheath 2 may include a pre-formeddistal end 9. The pre-formeddistal end 9 can be optimally shaped for advancement through heart chambers or intended venous pathways. The pre-formeddistal end 9 may also determine the deflection point of theouter sheath 2 upon application of a tensile force to thesteering tendon 7. - As shown in FIG. 3A, the
outer sheath 2 has an initial shape at the pre-formeddistal end 9. The direction of motion of theouter sheath 2 as it is deflected by thesteering tendon 7 and steering handle 6 is indicated by the bold arrows. The deflected positions of thesteering handle 6 andouter sheath 2 are indicated in phantom lines. Thesteering tendon 7 affects a bend angle and a bend radius of the preformeddistal end 9, thereby enabling deflection of a distal tip of the guide catheter. - The
outer sheath 2 may be formed of a polymeric tube similar to theinner sheath 1. Theouter sheath 2 is typically stiffer than theinner sheath 1, and may benefit from a multilayer construction that includes a metallic braid or coil. An inner lubricous lining made of PTFE or equivalent material can be provided within theouter sheath lumen 2A to reduce friction between the inner andouter sheaths steering tendon 7 can be disposed within theouter sheath lumen 2A. Thesteering tendon 7 can also be disposed along an outer surface of theouter sheath 2. Alternatively, theouter sheath 2 can contain asecond lumen 21 as seen in FIG. 3B. Thesteering tendon 7 is deployed within thesecond lumen 21. Thesteering tendon 7 may be formed of a metallic wire or ribbon, although other tensile members such as a high strength polymer fiber can also be employed with similar results. - A catheter embodying features of the present invention is particularly useful in applications such as implanting pacing and defibrillation leads into heart vessels. This procedure is illustrated FIG. 4. In such an application, the distal end of the catheter is typically introduced through a
percutaneous access point 10, such as in the left cephalic vein or left subclavian vein. Theinner sheath 1 can be retracted within theouter sheath 2 while the catheter is advanced through the access vessel into to the heart. As shown this example the catheter advances through the superior vena cava into theright atrium 11. In some cases, aguide wire 13 may be inserted through the venous pathway before the catheter is introduced, and the catheter then advanced over theguide wire 13 into the right atrium. - Once the distal tip of the
outer sheath 2 has reached the right atrium, theinner sheath 1 can be extended. Theinner sheath 1 is extended and rotated to locate thecoronary sinus ostium 12. Additional assistance in finding theostium 12 is provided by deflecting theouter sheath 2 via thesteering tendon 7. Once theinner sheath 1 has located theostium 12, theinner sheath 1 can be advanced as far as required into the coronary sinus. - If a
guide wire 13 was introduced prior to inserting the catheter, theguide wire 13 can be advanced through theinner sheath 1 into the coronary sinus. Theguide wire 13 is then distally extended beyond theinner sheath 1 into a branch of the coronary sinus. Theguide wire 13 can then be used to guide apacing lead 14 into the branch vessel. Thepacing lead 14 is advanced through theinner sheath 1 and seated into the branch of the coronary sinus. - At this point in the procedure, it may be desired to remove at least the
outer sheath 2. In one configuration, theouter sheath 2 can be made with a peel away feature. Turning to FIG. 5, a peel away feature may include one or more longitudinalpre-stress lines 15 extending from proximal to distal ends along theouter sheath 2. The advantages of a peel-away feature include the ability to proximally remove theouter sheath 2 over theinner sheath 1 seated without disturbing any proximal attachments on theinner sheath 1. Proximal attachments on theinner sheath 1 may include awing luer 5. - A peel-away feature of the
outer sheath 2 in a catheter according the present invention can further include the ability of the guide handle 3 to separate into at least two sections. As seen in FIG. 5, application of forces to the separation grips 16 can split theguide handle 3. The guide handle 3 is connected to theouter sheath 2, so guide handle separation can initiate outer sheath separation as well. Further details of exemplary peel-away features are disclosed in commonly owned U.S. application serial no. 10/036,640, filed Dec. 31, 2001 and entitled “Telescoping Guide Catheter With Peel-Away Outer Sheath” (Atty. Docket No. GUID.037US01), which is hereby incorporated herein by reference. - In some cases, it may be desirable to remove the
inner sheath 1 prior to introducing thepacing lead 14. In such a case, thepacing lead 14 is advanced through theouter sheath 2. This may be desirable as theouter sheath lumen 2A is larger than that of theinner sheath 1. In this scenario, theouter sheath 2 is distally advanced over theinner sheath 1 until theouter sheath 2 is seated in the coronary sinus. Theinner sheath 1 is then proximally retracted and removed, whereupon pacing lead insertion can proceed through theouter sheath 2. - This situation is illustrated in FIG. 6, where the
pacing lead 14 is shown extending from the distal end of theouter sheath 2. Theouter sheath 2 illustrated in FIG. 6 also employs a distally mountedocclusion balloon 15. Theocclusion balloon 15 can be inflated when theouter sheath 2 is in a vessel where blockage of blood flow is desired. Blood flow can be temporarily occluded in this way before injecting a contrast media, for example. Theocclusion balloon 15 is typically inflated by a fluid injected from a proximal end of theouter sheath 2. Methods of mounting and actuating theocclusion balloon 15 are well known in the art. - FIG. 7 illustrates an
occlusion balloon 16 mounted on the distal end of theinner sheath 1. Actuation and disposition of theocclusion balloon 16 is similar to that described for theocclusion balloon 15 mounted on theouter sheath 2. - Another useful configuration of a guide catheter according to the present invention includes attaching electrodes to a distal end of the guide catheter. FIG. 7 shows
electrodes 17 mounted on the distal end of theouter sheath 2. Theelectrodes 17 are typically flush mounted, and are connected to at least oneconductor 18 that is disposed between the distal and proximal ends of theinner sheath 1. - FIG. 8 shows
electrodes 19 mounted on theinner sheath 1 in a similar fashion as theelectrodes 17 on theouter sheath 2. Theelectrodes 19 are connected to at least oneconductor 20 that is disposed within theinner sheath 1. It is understood the electrodes may be disposed on both the inner andouter sheaths - The
electrodes electrodes - Another adaptation of a catheter according to the present invention includes attaching one or more pressure sensing devices to at least the distal end of the inner and/or
outer sheaths inner sheath 1, and can be deployed in a similar manner to theelectrodes 19 shown in FIG. 8. As with theelectrodes 19, at least oneconductor 20 would be coupled to the pressure sensing device and disposed within the inner orouter sheath outer sheaths - It will, of course, be understood that various modifications and additions can be made to the preferred embodiments discussed hereinabove without departing from the scope of the present invention. Accordingly, the scope of the present invention should not be limited by the particular embodiments described above, but should be defined only by the claims set forth below and equivalents thereof.
Claims (32)
1. A method, comprising:
providing a guide catheter, comprising:
an outer sheath comprising an open lumen and a pre-shaped distal end;
an inner sheath comprising an open lumen and a distal end having a pre-formed shape, the inner sheath disposed within the open lumen of the outer sheath, the distal end of the inner sheath conforming to a shape of the outer sheath when the inner sheath is retracted within the outer sheath;
a steering tendon disposed along the outer sheath, a distal end of the steering tendon connected to a distal tip of the outer sheath;
a guide handle connected to a proximal end of the outer sheath; and
a steering mechanism disposed on the guide handle, the steering mechanism connected to a proximal end of the steering tendon;
axially rotating and longitudinally translating the inner sheath relative to the outer sheath, the distal end of the inner sheath assuming the pre-formed shape when the distal end of the inner sheath is extended beyond the distal end of the outer sheath; and
providing a pulling force on the steering tendon to adjustably change a shape of the pre-shaped distal end of the outer sheath.
2. The method of claim 1 , further comprising advancing a payload through the open lumen of the inner sheath.
3. The method of claim 1 , further comprising advancing a pacing lead through the open lumen of the inner sheath.
4. The method of claim 1 , further comprising advancing a guide wire through the open lumen of the inner sheath.
5. The method of claim 1 , further comprising
proximally retracting the inner sheath to remove the inner sheath from the outer sheath; and
advancing a payload through the open lumen of the outer sheath.
6. The method of claim 1 , further comprising:
proximally retracting the inner sheath to remove the inner sheath from the outer sheath; and
advancing a pacing lead through the open lumen of the outer sheath.
7. The method of claim 1 , further comprising injecting a contrast media for venography into the open lumen of the inner sheath.
8. The method of claim 1 , wherein the outer sheath of the guide catheter further comprises at least one pre-stress line extending from the proximal end to a distal tip of the outer sheath, the method further comprising splitting the outer sheath while retracting the outer sheath in a proximal direction.
9. The method of claim 1 , further comprising delivering energy from the distal end of at least one of the inner and outer sheaths sufficient to ablate cardiac tissue.
10. The method of claim 1 , further comprising mapping cardiac tissue by use of one or more electrodes provided at the distal end of at least one of the inner and outer sheaths.
11. The method of claim 1 , further comprising sensing pressure at the distal end of at least one of the inner and outer sheaths.
12. The method of claim 1 , further comprising sensing temperature at the distal end of at least one of the inner and outer sheaths.
13. The method of claim 1 , further comprising sensing blood flow or blood velocity at the distal end of at least one of the inner and outer sheaths.
14. The method of claim 1 , further comprising sensing oxygen saturation at the distal end of at least one of the inner and outer sheaths.
15. The method of claim 1 , further comprising sensing acceleration at the distal end of at least one of the inner and outer sheaths.
16. The method of claim 1 , further comprising occluding blood flow proximate the distal end of at least one of the inner and outer sheaths.
17. A method, comprising:
providing a guide catheter, comprising:
an outer sheath comprising an open lumen and a pre-shaped distal end;
an inner sheath comprising an open lumen and a distal end having a pre-formed shape, the inner sheath disposed within the open lumen of the outer sheath, the distal end of the inner sheath conforming to a shape of the outer sheath when the inner sheath is retracted within the outer sheath;
a steering tendon disposed along the outer sheath, a distal end of the steering tendon connected to a distal tip of the outer sheath;
a guide handle connected to a proximal end of the outer sheath; and
a steering mechanism disposed on the guide handle, the steering mechanism connected to a proximal end of the steering tendon;
inserting a distal end of the catheter into a patient's right atrium via an access vessel;
distally extending the inner sheath from the outer sheath, the distal end of the inner sheath assuming the pre-formed shape upon extending beyond the distal end of the outer sheath; and
providing a pulling force on the steering tendon to modify an angle of the pre-shaped distal end of the outer sheath, axially rotating the inner sheath relative to the outer sheath, and longitudinally translating the inner sheath relative to the outer sheath to direct the distal end of the inner sheath for finding and cannulating the patient's coronary sinus.
18. The method of claim 17 , further comprising advancing a payload through the open lumen of the inner sheath to insert the payload into the coronary sinus.
19. The method of claim 17 , further comprising advancing a pacing lead through the open lumen of the inner sheath to insert the payload into the coronary sinus.
20. The method of claim 17 , further comprising advancing a guide wire through the open lumen of the inner sheath to locate the coronary sinus.
21. The method of claim 17 , further comprising:
proximally retracting the inner sheath to remove the inner sheath from the outer sheath after cannulating the patient's coronary sinus; and
advancing a payload through the open lumen of the outer sheath.
22. The method of claim 17 , further comprising:
proximally retracting the inner sheath to remove the inner sheath from the outer sheath after cannulating the patient's coronary sinus; and
advancing a pacing lead through the open lumen of the outer sheath.
23. The method of claim 17 , wherein the outer sheath of the guide catheter further comprises at least one pre-stress line extending from the proximal end to a distal tip of the outer sheath, the method further comprising splitting the outer sheath while retracting the outer sheath in a proximal direction.
24. The method of claim 17 , further comprising delivering energy from the distal end of at least one of the inner and outer sheaths sufficient to ablate cardiac tissue.
25. The method of claim 17 , further comprising mapping cardiac tissue by use of one or more electrodes provided at the distal end of at least one of the inner and outer sheaths.
26. The method of claim 17 , further comprising sensing pressure at the distal end of at least one of the inner and outer sheaths.
27. The method of claim 17 , further comprising sensing temperature at the distal end of at least one of the inner and outer sheaths.
28. The method of claim 17 , further comprising sensing blood flow or blood velocity at the distal end of at least one of the inner and outer sheaths.
29. The method of claim 17 , further comprising sensing oxygen saturation at the distal end of at least one of the inner and outer sheaths.
30. The method of claim 17 , further comprising sensing acceleration at the distal end of at least one of the inner and outer sheaths.
31. The method of claim 17 , further comprising occluding blood flow proximate the distal end of at least one of the inner and outer sheaths.
32. The method of claim 17 , further comprising injecting a contrast media for venography into the open lumen of the inner sheath after finding and cannulating the coronary sinus.
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US10/890,875 US20040260236A1 (en) | 2002-01-07 | 2004-07-14 | Guide catheter steering using pre-shaped rotatable shaft |
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US10/041,911 US7493156B2 (en) | 2002-01-07 | 2002-01-07 | Steerable guide catheter with pre-shaped rotatable shaft |
US10/890,875 US20040260236A1 (en) | 2002-01-07 | 2004-07-14 | Guide catheter steering using pre-shaped rotatable shaft |
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US10/041,911 Division US7493156B2 (en) | 2002-01-07 | 2002-01-07 | Steerable guide catheter with pre-shaped rotatable shaft |
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