US20050080444A1 - Transesophageal gastric reduction device, system and method - Google Patents

Transesophageal gastric reduction device, system and method Download PDF

Info

Publication number
US20050080444A1
US20050080444A1 US10/686,427 US68642703A US2005080444A1 US 20050080444 A1 US20050080444 A1 US 20050080444A1 US 68642703 A US68642703 A US 68642703A US 2005080444 A1 US2005080444 A1 US 2005080444A1
Authority
US
United States
Prior art keywords
stomach
tissue
expandable structure
expandable
gastric reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/686,427
Inventor
Stefan Kraemer
John Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Endogastric Solutions Inc
Original Assignee
Kraemer Stefan J.M.
Adams John M.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/686,427 priority Critical patent/US20050080444A1/en
Application filed by Kraemer Stefan J.M., Adams John M. filed Critical Kraemer Stefan J.M.
Priority to CN200480030254.2A priority patent/CN101076289A/en
Priority to PCT/US2004/033905 priority patent/WO2005037072A2/en
Priority to JP2006535653A priority patent/JP2007514462A/en
Priority to EP04795109.0A priority patent/EP1681984A4/en
Publication of US20050080444A1 publication Critical patent/US20050080444A1/en
Priority to US11/823,998 priority patent/US20070260276A1/en
Assigned to ENDOGASTRIC SOLUTIONS, INC. reassignment ENDOGASTRIC SOLUTIONS, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ENDO GASTRIC SOLUTIONS, INC.
Assigned to ENDO GASTRIC SOLUTIONS, INC. reassignment ENDO GASTRIC SOLUTIONS, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ESOPHYX, INC.
Assigned to CHICAGO GROWTH PARTNERS, LP, DE NOVO VENTURES III, LP, MPM BIOVENTURES III PARALLEL FUND, L.P., MPM BIOVENTURES III, L.P., MPM BIOVENTURES III-QP, L.P., MPM BIOVENTURES II-QP, L.P., MPM ASSET MANAGEMENT INVESTORS 2000 B LLC, MPM ASSET MANAGEMENT INVESTORS 2003 BVIII LLC, MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS KG, MPM BIOVENTURES II, L.P., MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG, OAKWOOD MEDICAL INVESTORS IV (QP), L.L.C., OAKWOOD MEDICAL INVESTORS IV, L.L.C., FOUNDATION MEDICAL PARTNERS II, L.P, ADVANCED TECHNOLOGY VENTURES VII (B), L.P., ADVANCED TECHNOLOGY VENTURES VII (C), L.P., ADVANCED TECHNOLOGY VENTURES VII, L.P., ATV ENTREPRENEURS VII, L.P. reassignment CHICAGO GROWTH PARTNERS, LP SECURITY AGREEMENT Assignors: ENDOGASTRIC SOLUTIONS, INC.
Assigned to ENDOGASTRIC SOLUTIONS, INC. reassignment ENDOGASTRIC SOLUTIONS, INC. RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: OAKWOOD MEDICAL INVESTORS IV (QP), L.L.C., OAKWOOD MEDICAL INVESTORS IV, L.L.C., ADVANCED TECHNOLOGY VENTURES VII (B), L.P., ADVANCED TECHNOLOGY VENTURES VII (C), L.P., ADVANCED TECHNOLOGY VENTURES VII, L.P., ATV ENTREPRENEURS VII, L.P., FOUNDATION MEDICAL PARTNERS II, L.P., CHICAGO GROWTH PARTNERS, LP, DE NOVO VENTURES III, LP, MPM ASSET MANAGEMENT INVESTORS 2000 B LLC, MPM ASSET MANAGEMENT INVESTORS 2003 BVIII LLC, MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS KG, MPM BIOVENTURES II, L.P., MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG, MPM BIOVENTURES III PARALLEL FUND, L.P., MPM BIOVENTURES III, L.P., MPM BIOVENTURES III-QP, L.P., MPM BIOVENTURES II-QP, L.P.
Priority to US13/069,992 priority patent/US8430891B2/en
Abandoned legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0083Reducing the size of the stomach, e.g. gastroplasty
    • A61F5/0086Reducing the size of the stomach, e.g. gastroplasty using clamps, folding means or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/122Clamps or clips, e.g. for the umbilical cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/128Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
    • A61B17/1285Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00818Treatment of the gastro-intestinal system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/30Surgical pincettes without pivotal connections
    • A61B2017/306Surgical pincettes without pivotal connections holding by means of suction
    • A61B2017/308Surgical pincettes without pivotal connections holding by means of suction with suction cups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes

Definitions

  • the present invention is generally directed to a therapy for treating obesity.
  • the present invention is more particularly directed to a transesophageal gastric reduction device, system, and method for performing gastric reduction surgery while minimizing surgical invasion.
  • Obesity is a complex chronic disease involving environment, genetic, physiologic, metabolic, behavioral and psychological components. It is the second leading cause of preventable death in the United States.
  • Obesity is not limited to the United States but is increasing worldwide. It is increasing worldwide in both developing and developed countries and is thought to be caused by environmental and behavioral changes resulting from economic development, modernization, and urbanization. Obesity is increasing in children as well. It is believed that the true health consequences of obesity have not yet become totally apparent.
  • Obesity is currently treated by dietary therapy, physical activity, behavioral therapy, drug therapy, and combinations thereof.
  • Dietary therapy involves instruction on how to adjust a diet to reduce the number of calories eaten.
  • Physical activity strategies include use of aerobic exercise, brisk walking, jogging, cycling, and swimming.
  • Behavioral therapy involves changing diet and physical activity patterns and habits to new behaviors that promote weight loss. Drug therapy is most often used only in conjunction with appropriate lifestyle modifications.
  • bands or staples are used to create food intake restriction.
  • the bands or staples are surgically placed near the top of the stomach to section off a portion that is often called a stomach pouch.
  • a small outlet about the size of a pencil eraser, is left at the bottom of the stomach pouch. Since the outlet is small, food stays in the pouch longer and the feeling of fullness lasts for a longer time.
  • Current operative procedures for restrictive surgery include vertical banded gastroplasty, gastric banding, and laparoscopic gastric banding.
  • vertical banded gastroplasty a stomach pouch is surgically created.
  • gastric banding a band is used to create the stomach pouch.
  • laparoscopic gastric banding a less invasive procedure, smaller incisions are made to apply the band.
  • the band is inflatable and may be adjusted over time.
  • Each of the foregoing therapies for severe obesity has its risks and side effects. Each is invasive surgery and hence exhibits the risks commonly associated with all surgical procedures. Complications may include leaking of stomach juices into the abdomen, injury to the spleen, band slippage, erosion of the band, breakdown of the staple line, and stomach pouch stretching from overeating.
  • the present invention is directed to an alternative device, system, and method for achieving gastric reduction.
  • the device, system, and method do not require surgical incisions and is thus less invasive than previous reduction therapies.
  • the invention generally provides a gastric reduction device comprising an expandable structure placeable in a stomach which, when expanded, occupies a portion of the stomach and an evacuator that deflates the stomach around the expandable structure to form a gastric reduction pouch.
  • the expandable structure is preferably placeable in the stomach immediately adjacent and distal to an esophageal orifice associated with the stomach.
  • the expandable structure may comprise a balloon.
  • the evacuator may extend distally from the expandable member and terminate within the stomach.
  • the device may further comprise a fastener that maintains the gastric reduction pouch.
  • the fastener is preferably arranged to inwardly fold stomach tissue to fasten serosa tissue to serosa tissue of the stomach.
  • the fastener may comprise a cylindrically shaped member having opposed ends and tissue engaging arms radially extending from each of the opposed ends.
  • the device may further comprise an endoscope that extends through the expandable member.
  • the expandable member preferably forms a spherically shaped ring when expanded.
  • the spherically shaped ring may include an axial passageway permitting the evacuator to extend through the passageway.
  • the present invention still further provides a gastric reduction system comprising an expandable structure, placeable in a stomach, and, when expanded, occupying a fractional volume of the stomach.
  • the system further includes an evacuator that deflates the stomach and draws the stomach to and around the expandable member to form a gastric reduction pouch with stomach tissue and a fastener that is operable to maintain the gastric reduction pouch.
  • the fastener may be carried by the evacuator.
  • the present invention still further provides a method comprising the steps of positioning an expandable structure in a stomach of a patient, expanding the expandable structure to occupy a portion of the stomach, and drawing the stomach around the expandable structure to form a gastric reduction pouch.
  • the positioning step may include placing the expandable structure immediately distal to an esophageal orifice associated with the stomach.
  • the expandable structure may comprise a balloon and the expanding step may include inflating the balloon.
  • the deflating step may include evacuating the stomach.
  • an evacuator may be fed into the stomach.
  • the evacuator may be fed into the stomach through the expandable structure.
  • the method may further include the step of maintaining the gastric reduction pouch.
  • Maintaining the gastric reduction pouch may include inwardly folding stomach tissue to contact serosa tissue to serosa tissue to form a stoma.
  • the inwardly folded stomach tissue may be fastened together.
  • FIG. 1 is a front cross-sectional view of the esophageal-gastro-intestinal tract from a lower portion of the esophagus to the duodenum;
  • FIG. 2 is a perspective view with portions cut away of a device embodying the present invention
  • FIG. 3 is a perspective view with portions cut away of the device of FIG. 2 illustrating partial deployment of a fastener in accordance with the present invention
  • FIG. 4 is a perspective view with portions cut away of the device of FIG. 2 with the fastener in a further stage of deployment;
  • FIG. 5 is a cross-sectional view of an esophagus and stomach with a device embodying the present invention in an initial stage of gastric reduction therapy in accordance with the present invention
  • FIG. 6 is a cross-sectional view similar to FIG. 5 of the device in a further stage of the therapy
  • FIG. 7 is a cross-sectional view similar to FIG. 5 of the device delivering a fastener in a still further stage of the therapy;
  • FIG. 8 is a cross-sectional view similar to FIG. 5 of the device and fastener in a final stage of the therapy.
  • FIG. 9 is a cross-sectional view similar to FIG. 5 after completion of the therapy and removal of the device embodying the present invention.
  • FIG. 1 is a front cross-sectional view of the esophageal-gastro-intestinal tract 40 from a lower portion of the esophagus 41 to the duodenum 42 .
  • the stomach 43 is characterized by the greater curvature 44 on the anatomical left side and the lesser curvature 45 on the anatomical right side.
  • the tissue of the outer surfaces of those curvatures is referred to in the art as serosa tissue. As will be seen subsequently, the nature of the serosa tissue is used to advantage for its ability to bond to like serosa tissue.
  • the fundus 46 of the greater curvature 44 forms the superior portion of the stomach 43 , and traps gas and air bubbles for burping.
  • the esophageal tract 41 enters the stomach 43 at an esophageal orifice 58 below the superior portion of the fundus 46 , forming a cardiac notch 47 and an acute angle with respect to the fundus 46 known as the Angle of His 57 .
  • the lower esophageal sphincter (LES) 48 is a discriminating sphincter able to distinguish between burping gas, liquids, and solids, and works in conjunction with the fundus 46 to burp.
  • the gastroesophageal flap valve (GEFV) 49 includes a moveable portion and an opposing more stationary portion.
  • the moveable portion of the GEFV 49 is an approximately 180 degree, semicircular, gastroesophageal flap 50 (alternatively referred to as a “normal moveable flap” or “moveable flap”) formed of tissue at the intersection between the esophagus 41 and the stomach 43 .
  • the opposing more stationary portion of the GEFV 49 comprises a portion of the lesser curvature 45 of the stomach 43 adjacent to its junction with the esophagus 41 .
  • the gastroesophageal flap 50 of the GEFV 49 principally comprises tissue adjacent to the fundus 46 portion of the stomach 43 , is about 4 to 5 cm long ( 51 ) at it longest portion, and the length may taper at its anterior and posterior ends.
  • the gastroesophageal flap 50 is partially held against the lesser curvature 45 portion of the stomach 43 by the pressure differential between the stomach 43 and the thorax, and partially by the resiliency and the anatomical structure of the GEFV 49 , thus providing the valving function.
  • the GEFV 49 is similar to a flutter valve, with the gastroesophageal flap 50 being flexible and closeable against the other more stationary side.
  • the esophageal tract is controlled by an upper esophageal sphincter (UES) near the mouth for swallowing, and by the LES 48 and the GEFV 49 at the stomach.
  • the normal anti-reflux barrier is primarily formed by the LES 48 and the GEFV 49 acting in concert to allow food and liquid to enter the stomach, and to considerably resist reflux of stomach contents into the esophagus 48 past the gastroesophageal tissue junction 52 .
  • Tissue aboral of the gastroesophageal tissue junction 52 is generally considered part of the stomach because the tissue protected from stomach acid by its own protective mechanisms.
  • Tissue oral of the gastroesophageal junction 52 is generally considered part of the esophagus and it is not protected from injury by prolonged exposure to stomach acid.
  • the juncture of the stomach and esophageal tissues form a zigzag line, which is sometimes referred to as the “Z-line.”
  • stomach means the tissue aboral of the gastroesophageal junction 52 .
  • FIG. 2 shows a device 60 embodying the present invention.
  • the device 60 permits transesophageal gastric reduction for treating severe obesity.
  • the device 60 generally includes an expandable structure 70 and an evacuator 80 .
  • Shown further in FIG. 2 is a fastener 90 which the device 60 delivers to maintain a formed gastric reduction pouch.
  • the expandable structure 70 takes the form of an inflatable ring-shaped balloon 72 which is integrally formed on and carried by an outer catheter 74 .
  • the ring-shaped balloon 72 and catheter 74 define an axial passageway 76 .
  • the balloon may be a compliant balloon formed of latex or polyurethane, for example. It may alternatively be a non-compliant balloon formed of polyethylene. A non-compliant balloon may be preferred as it maintains a fixed shape and size once totally inflated rendering the size of the balloon is rendered predictable.
  • the evacuator 80 comprises an endoscope 82 which includes a light source 84 , a viewer 86 , and a working channel 88 . Endoscopes of this type are well known in the art.
  • the working channel 88 is employed for evacuating the stomach once the device 60 is in place within the stomach and the balloon 72 has been inflated. This will become more apparent subsequently.
  • the evacuator 80 extends through the expandable structure 70 . More specifically, the endoscope 82 may be advanced through the axial passageway 76 to terminate distal to the expandable structure 70 to facilitate the evacuation of the stomach.
  • the fastener 90 may be carried by the endoscope 82 and also advanced through the axial passageway 76 along the endoscope 82 by a tubular pusher 100 .
  • the fastener 90 is preferably formed of a shape memory material such as Nitinol or a shape memory plastic, for example, so as to be self-deploying when advanced past the distal end 78 of the catheter 74 . It alternatively may be formed of stainless steel but would then require forced expansion as, for example, a balloon as is well known in the art.
  • FIG. 3 illustrates the fastener 90 during an initial stage of its deployment.
  • the fastener 90 prior to its deployment takes the form of a cylindrically shaped member 92 having opposed ends from which first and second sets of tissue engaging arms radially extend after deployment. As will be noted in FIG.
  • a first set of tissue engaging arms 93 are radially extending from the cylindrical member 92 as the fastener 90 is advanced by the catheter 100 past the distal end 78 of the catheter 74 .
  • the cylindrical center portion of the cylindrical member 92 is exposed. This forms a channel through which ingested food may pass out of the gastric reduction pouch after it is formed and maintained by the fastener 90 .
  • FIG. 5 it illustrates an initial stage of forming the gastric reduction pouch in accordance with the present invention.
  • the expandable structure 70 has been advanced through the esophagus 41 on the catheter 74 so that it is placed in the stomach immediately adjacent and distal to the esophageal orifice 58 .
  • the endoscope 82 is advanced through the axial passageway of the catheter 74 and expandable structure 70 until it is distal to the catheter 74 and expandable structure 70 within the stomach 43 .
  • the expandable structure 70 is expanded to define the size and shape of the gastric reduction pouch to be formed.
  • the expandable structure 70 comprises a balloon 72 which may be inflated as illustrated in FIG. 6 .
  • the balloon 72 has been inflated and occupies a fraction or portion of the stomach 43 .
  • the balloon 72 may be inflated through a lumen (not shown) in the catheter 74 in a manner well known in the art.
  • the stomach 43 is evacuated through the working channel of the endoscope 82 to cause the stomach to be drawn around the balloon 72 .
  • the fastener 90 is then advanced down the endoscope 82 by the pusher 100 for deploying the fastener 90 .
  • the fastener 90 is partially deployed with the first set of tissue engaging arms 93 radially extending from the cylindrical body 92 of the fastener 90 .
  • the second set of tissue engaging arms 95 are released from the catheter 74 to radially extend from the cylindrical body 92 of the fastener 90 .
  • the shape memory of the fastener 90 may be used to advantage by which the opposed sets of radially extending tissue engaging arms 93 and 95 together with the drawing of the stomach around the balloon 72 inwardly folds the outer surfaces of the stomach 43 to cause contact between adjacent outer surfaces of the stomach about the cylindrical body 92 of the fastener 90 .
  • the outer surface of the stomach comprises serosa tissue which develops a bond after contacting like tissue within a short period of time. This bond between the outer surfaces of the contacting stomach tissue will assist the fastener 90 in maintaining the gastric reduction pouch thus formed.
  • the assembly and device 60 is removed from the stomach. This may be achieved by first drawing the pusher 100 out of the catheter 74 . Then, the balloon 72 may be deflated permitting the balloon 72 and catheter 74 to be withdrawn from the stomach on the endoscope 82 . Lastly, the endoscope 82 may be withdrawn through the fastener 90 , through the gastric reduction pouch formed by the assembly and device 60 , and the esophagus 41 . This leaves the esophageal-gastro-intestinal tract 40 in a condition as illustrated in FIG. 9 . Here it may be seen that the gastric reduction pouch 110 has been formed between the esophagus 41 and the remaining stomach 43 . The fastener 90 may remain in place to maintain the gastric reduction pouch 110 .
  • the gastric reduction pouch 110 presents a smaller volume to accommodate ingested food thus providing the patient with an earlier sense of being full and a longer time of feeling full.
  • the process of forming the gastric reduction pouch 110 with the device 60 embodying the present invention has been performed in a transesophageal manner without the need of any surgical incisions.
  • the therapy contemplated herein is much less invasive than previous therapies for providing gastric reduction therapy. All of the advantages of gastric reduction therapy are available while substantially reducing the risks attendant to general surgery.

Abstract

A gastric reduction system and method provides for transesophageal formation of a gastric reduction pouch of the stomach. The system includes an expandable structure which may be placed in a stomach and expanded to occupy a fractional volume of the stomach. An evacuator is then fed through the expandable structure and utilized to deflate the stomach and draw the stomach to and around the expandable structure to form the gastric reduction pouch. A self-deploying fastener is then deployed to maintain the gastric reduction pouch.

Description

    FIELD OF THE INVENTION
  • The present invention is generally directed to a therapy for treating obesity. The present invention is more particularly directed to a transesophageal gastric reduction device, system, and method for performing gastric reduction surgery while minimizing surgical invasion.
  • BACKGROUND OF THE INVENTION
  • Obesity is a complex chronic disease involving environment, genetic, physiologic, metabolic, behavioral and psychological components. It is the second leading cause of preventable death in the United States.
  • Obesity affects nearly one-third of the adult American population (approximately 60 million). The number of overweight and obese Americans has continued to increase since 1960. The trend is not slowing down. Today, 64.5% of adult Americans are categorized as being overweight or obese. Each year, obesity causes at least 300,000 excess deaths in the United States, and healthcare costs of American adults with obesity amounted to approximately $100,000,000,000 (100 billion dollars).
  • Obesity is not limited to the United States but is increasing worldwide. It is increasing worldwide in both developing and developed countries and is thought to be caused by environmental and behavioral changes resulting from economic development, modernization, and urbanization. Obesity is increasing in children as well. It is believed that the true health consequences of obesity have not yet become totally apparent.
  • Obesity is currently treated by dietary therapy, physical activity, behavioral therapy, drug therapy, and combinations thereof. Dietary therapy involves instruction on how to adjust a diet to reduce the number of calories eaten. Physical activity strategies include use of aerobic exercise, brisk walking, jogging, cycling, and swimming. Behavioral therapy involves changing diet and physical activity patterns and habits to new behaviors that promote weight loss. Drug therapy is most often used only in conjunction with appropriate lifestyle modifications.
  • One last treatment for obesity is surgery. Surgery is a treatment option which is generally reserved for persons with severe obesity and those who are morbidly obese. In addition, surgery is not generally performed until other methods of weight loss have been attempted and have been found to be ineffective. Persons who are severely obese are generally unable to physically perform routine daily activities, whether work-related or family functions and have a severely impaired quality of life due to the severity of their obesity.
  • Most obesity surgeries involve making changes to the stomach and/or small intestines. Currently, there are two types of obesity surgery: (1) restrictive; and (2) combined restrictive and malabsorptive. Operative procedures have been developed for each type of surgery. Each type of surgery has its own risks and side effects.
  • In restrictive surgery, bands or staples are used to create food intake restriction. The bands or staples are surgically placed near the top of the stomach to section off a portion that is often called a stomach pouch. A small outlet, about the size of a pencil eraser, is left at the bottom of the stomach pouch. Since the outlet is small, food stays in the pouch longer and the feeling of fullness lasts for a longer time. Current operative procedures for restrictive surgery include vertical banded gastroplasty, gastric banding, and laparoscopic gastric banding. In vertical banded gastroplasty, a stomach pouch is surgically created. In gastric banding, a band is used to create the stomach pouch. In laparoscopic gastric banding, a less invasive procedure, smaller incisions are made to apply the band. The band is inflatable and may be adjusted over time.
  • Each of the foregoing therapies for severe obesity has its risks and side effects. Each is invasive surgery and hence exhibits the risks commonly associated with all surgical procedures. Complications may include leaking of stomach juices into the abdomen, injury to the spleen, band slippage, erosion of the band, breakdown of the staple line, and stomach pouch stretching from overeating.
  • However, reductive surgery has proven successful. About 80% of patients lose some weight and 30% reach a normal weight. Hence, the benefits of gastric reduction surgery are generally believed to outweigh the attendant risks and potential complications.
  • The present invention is directed to an alternative device, system, and method for achieving gastric reduction. As will be seen hereinafter, the device, system, and method do not require surgical incisions and is thus less invasive than previous reduction therapies.
  • SUMMARY OF THE INVENTION
  • The invention generally provides a gastric reduction device comprising an expandable structure placeable in a stomach which, when expanded, occupies a portion of the stomach and an evacuator that deflates the stomach around the expandable structure to form a gastric reduction pouch. The expandable structure is preferably placeable in the stomach immediately adjacent and distal to an esophageal orifice associated with the stomach.
  • The expandable structure may comprise a balloon. The evacuator may extend distally from the expandable member and terminate within the stomach.
  • The device may further comprise a fastener that maintains the gastric reduction pouch. The fastener is preferably arranged to inwardly fold stomach tissue to fasten serosa tissue to serosa tissue of the stomach. The fastener may comprise a cylindrically shaped member having opposed ends and tissue engaging arms radially extending from each of the opposed ends.
  • The device may further comprise an endoscope that extends through the expandable member. The expandable member preferably forms a spherically shaped ring when expanded. The spherically shaped ring may include an axial passageway permitting the evacuator to extend through the passageway.
  • The present invention still further provides a gastric reduction system comprising an expandable structure, placeable in a stomach, and, when expanded, occupying a fractional volume of the stomach. The system further includes an evacuator that deflates the stomach and draws the stomach to and around the expandable member to form a gastric reduction pouch with stomach tissue and a fastener that is operable to maintain the gastric reduction pouch. The fastener may be carried by the evacuator.
  • The present invention still further provides a method comprising the steps of positioning an expandable structure in a stomach of a patient, expanding the expandable structure to occupy a portion of the stomach, and drawing the stomach around the expandable structure to form a gastric reduction pouch. The positioning step may include placing the expandable structure immediately distal to an esophageal orifice associated with the stomach. The expandable structure may comprise a balloon and the expanding step may include inflating the balloon.
  • The deflating step may include evacuating the stomach. To this end, an evacuator may be fed into the stomach. The evacuator may be fed into the stomach through the expandable structure.
  • The method may further include the step of maintaining the gastric reduction pouch. Maintaining the gastric reduction pouch may include inwardly folding stomach tissue to contact serosa tissue to serosa tissue to form a stoma. The inwardly folded stomach tissue may be fastened together.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • The features of the present invention which are believed to be novel are set forth with particularity in the appended claims. The invention, together with further features and advantages thereof, may best be understood by making reference to the following description taken in conjunction with the accompanying drawings, in the several figures of which like reference numerals identify identical elements, and wherein:
  • FIG. 1 is a front cross-sectional view of the esophageal-gastro-intestinal tract from a lower portion of the esophagus to the duodenum;
  • FIG. 2 is a perspective view with portions cut away of a device embodying the present invention;
  • FIG. 3 is a perspective view with portions cut away of the device of FIG. 2 illustrating partial deployment of a fastener in accordance with the present invention;
  • FIG. 4 is a perspective view with portions cut away of the device of FIG. 2 with the fastener in a further stage of deployment;
  • FIG. 5 is a cross-sectional view of an esophagus and stomach with a device embodying the present invention in an initial stage of gastric reduction therapy in accordance with the present invention;
  • FIG. 6 is a cross-sectional view similar to FIG. 5 of the device in a further stage of the therapy;
  • FIG. 7 is a cross-sectional view similar to FIG. 5 of the device delivering a fastener in a still further stage of the therapy;
  • FIG. 8 is a cross-sectional view similar to FIG. 5 of the device and fastener in a final stage of the therapy; and
  • FIG. 9 is a cross-sectional view similar to FIG. 5 after completion of the therapy and removal of the device embodying the present invention.
  • DETAILED DESCRIPTION OF THE INVENTION
  • FIG. 1 is a front cross-sectional view of the esophageal-gastro-intestinal tract 40 from a lower portion of the esophagus 41 to the duodenum 42. The stomach 43 is characterized by the greater curvature 44 on the anatomical left side and the lesser curvature 45 on the anatomical right side. The tissue of the outer surfaces of those curvatures is referred to in the art as serosa tissue. As will be seen subsequently, the nature of the serosa tissue is used to advantage for its ability to bond to like serosa tissue. The fundus 46 of the greater curvature 44 forms the superior portion of the stomach 43, and traps gas and air bubbles for burping. The esophageal tract 41 enters the stomach 43 at an esophageal orifice 58 below the superior portion of the fundus 46, forming a cardiac notch 47 and an acute angle with respect to the fundus 46 known as the Angle of His 57. The lower esophageal sphincter (LES) 48 is a discriminating sphincter able to distinguish between burping gas, liquids, and solids, and works in conjunction with the fundus 46 to burp. The gastroesophageal flap valve (GEFV) 49 includes a moveable portion and an opposing more stationary portion. The moveable portion of the GEFV 49 is an approximately 180 degree, semicircular, gastroesophageal flap 50 (alternatively referred to as a “normal moveable flap” or “moveable flap”) formed of tissue at the intersection between the esophagus 41 and the stomach 43. The opposing more stationary portion of the GEFV 49 comprises a portion of the lesser curvature 45 of the stomach 43 adjacent to its junction with the esophagus 41. The gastroesophageal flap 50 of the GEFV 49 principally comprises tissue adjacent to the fundus 46 portion of the stomach 43, is about 4 to 5 cm long (51) at it longest portion, and the length may taper at its anterior and posterior ends. The gastroesophageal flap 50 is partially held against the lesser curvature 45 portion of the stomach 43 by the pressure differential between the stomach 43 and the thorax, and partially by the resiliency and the anatomical structure of the GEFV 49, thus providing the valving function. The GEFV 49 is similar to a flutter valve, with the gastroesophageal flap 50 being flexible and closeable against the other more stationary side.
  • The esophageal tract is controlled by an upper esophageal sphincter (UES) near the mouth for swallowing, and by the LES 48 and the GEFV 49 at the stomach. The normal anti-reflux barrier is primarily formed by the LES 48 and the GEFV 49 acting in concert to allow food and liquid to enter the stomach, and to considerably resist reflux of stomach contents into the esophagus 48 past the gastroesophageal tissue junction 52. Tissue aboral of the gastroesophageal tissue junction 52 is generally considered part of the stomach because the tissue protected from stomach acid by its own protective mechanisms. Tissue oral of the gastroesophageal junction 52 is generally considered part of the esophagus and it is not protected from injury by prolonged exposure to stomach acid. At the gastroesophageal junction 52, the juncture of the stomach and esophageal tissues form a zigzag line, which is sometimes referred to as the “Z-line.” For the purposes of these specifications, including the claims, “stomach” means the tissue aboral of the gastroesophageal junction 52.
  • FIG. 2 shows a device 60 embodying the present invention. As will be seen hereinafter, the device 60 permits transesophageal gastric reduction for treating severe obesity. The device 60 generally includes an expandable structure 70 and an evacuator 80. Shown further in FIG. 2 is a fastener 90 which the device 60 delivers to maintain a formed gastric reduction pouch.
  • The expandable structure 70, in accordance with this embodiment, takes the form of an inflatable ring-shaped balloon 72 which is integrally formed on and carried by an outer catheter 74. The ring-shaped balloon 72 and catheter 74 define an axial passageway 76. The balloon may be a compliant balloon formed of latex or polyurethane, for example. It may alternatively be a non-compliant balloon formed of polyethylene. A non-compliant balloon may be preferred as it maintains a fixed shape and size once totally inflated rendering the size of the balloon is rendered predictable.
  • The evacuator 80, in accordance with this embodiment, comprises an endoscope 82 which includes a light source 84, a viewer 86, and a working channel 88. Endoscopes of this type are well known in the art. The working channel 88 is employed for evacuating the stomach once the device 60 is in place within the stomach and the balloon 72 has been inflated. This will become more apparent subsequently.
  • As will be noted in FIG. 2, the evacuator 80 extends through the expandable structure 70. More specifically, the endoscope 82 may be advanced through the axial passageway 76 to terminate distal to the expandable structure 70 to facilitate the evacuation of the stomach. The fastener 90 may be carried by the endoscope 82 and also advanced through the axial passageway 76 along the endoscope 82 by a tubular pusher 100.
  • The fastener 90 is preferably formed of a shape memory material such as Nitinol or a shape memory plastic, for example, so as to be self-deploying when advanced past the distal end 78 of the catheter 74. It alternatively may be formed of stainless steel but would then require forced expansion as, for example, a balloon as is well known in the art. FIG. 3 illustrates the fastener 90 during an initial stage of its deployment. The fastener 90 prior to its deployment takes the form of a cylindrically shaped member 92 having opposed ends from which first and second sets of tissue engaging arms radially extend after deployment. As will be noted in FIG. 3, a first set of tissue engaging arms 93 are radially extending from the cylindrical member 92 as the fastener 90 is advanced by the catheter 100 past the distal end 78 of the catheter 74. Upon further displacement of the fastener 90 as illustrated in FIG. 4, the cylindrical center portion of the cylindrical member 92 is exposed. This forms a channel through which ingested food may pass out of the gastric reduction pouch after it is formed and maintained by the fastener 90.
  • Referring now to FIG. 5, it illustrates an initial stage of forming the gastric reduction pouch in accordance with the present invention. Here it will be seen that the expandable structure 70 has been advanced through the esophagus 41 on the catheter 74 so that it is placed in the stomach immediately adjacent and distal to the esophageal orifice 58. After the expandable member is positioned adjacent the esophageal orifice 58, the endoscope 82 is advanced through the axial passageway of the catheter 74 and expandable structure 70 until it is distal to the catheter 74 and expandable structure 70 within the stomach 43.
  • After the expandable structure 70 and endoscope 82 are placed in the stomach 43 as illustrated in FIG. 5, the expandable structure 70 is expanded to define the size and shape of the gastric reduction pouch to be formed. In accordance with this preferred embodiment, the expandable structure 70 comprises a balloon 72 which may be inflated as illustrated in FIG. 6. Here it may be seen that the balloon 72 has been inflated and occupies a fraction or portion of the stomach 43. The balloon 72 may be inflated through a lumen (not shown) in the catheter 74 in a manner well known in the art.
  • After the balloon 72 has been expanded to its desired size, the stomach 43 is evacuated through the working channel of the endoscope 82 to cause the stomach to be drawn around the balloon 72.
  • Once the stomach tissue has been drawn around the balloon 72, the fastener 90 is then advanced down the endoscope 82 by the pusher 100 for deploying the fastener 90. As shown in FIG. 7, the fastener 90 is partially deployed with the first set of tissue engaging arms 93 radially extending from the cylindrical body 92 of the fastener 90. Upon further advancement of the fastener 90 as illustrated in FIG. 8, the second set of tissue engaging arms 95 are released from the catheter 74 to radially extend from the cylindrical body 92 of the fastener 90.
  • The shape memory of the fastener 90 may be used to advantage by which the opposed sets of radially extending tissue engaging arms 93 and 95 together with the drawing of the stomach around the balloon 72 inwardly folds the outer surfaces of the stomach 43 to cause contact between adjacent outer surfaces of the stomach about the cylindrical body 92 of the fastener 90. The outer surface of the stomach comprises serosa tissue which develops a bond after contacting like tissue within a short period of time. This bond between the outer surfaces of the contacting stomach tissue will assist the fastener 90 in maintaining the gastric reduction pouch thus formed.
  • Once the fastener 90 has been fully deployed as illustrated in FIG. 8, the assembly and device 60 is removed from the stomach. This may be achieved by first drawing the pusher 100 out of the catheter 74. Then, the balloon 72 may be deflated permitting the balloon 72 and catheter 74 to be withdrawn from the stomach on the endoscope 82. Lastly, the endoscope 82 may be withdrawn through the fastener 90, through the gastric reduction pouch formed by the assembly and device 60, and the esophagus 41. This leaves the esophageal-gastro-intestinal tract 40 in a condition as illustrated in FIG. 9. Here it may be seen that the gastric reduction pouch 110 has been formed between the esophagus 41 and the remaining stomach 43. The fastener 90 may remain in place to maintain the gastric reduction pouch 110. The gastric reduction pouch 110 presents a smaller volume to accommodate ingested food thus providing the patient with an earlier sense of being full and a longer time of feeling full.
  • As will be noted from the foregoing, the process of forming the gastric reduction pouch 110 with the device 60 embodying the present invention has been performed in a transesophageal manner without the need of any surgical incisions. Hence, the therapy contemplated herein is much less invasive than previous therapies for providing gastric reduction therapy. All of the advantages of gastric reduction therapy are available while substantially reducing the risks attendant to general surgery.
  • While particular embodiments of the present invention have been shown and described, modifications may be made, and it is therefore intended in the appended claims to cover all such changes and modifications which fall within the true spirit and scope of the invention.

Claims (34)

1. A gastric reduction device comprising:
an expandable structure, placeable in a stomach, the expandable structure, when expanded, occupying a portion of the stomach; and
an evacuator that deflates the stomach around the expandable structure to form a gastric reduction pouch.
2. The device of claim 1 wherein the expandable structure is placeable in the stomach immediately adjacent and distal to an esophageal orifice associated with the stomach.
3. The device of claim 1 wherein the expandable structure comprises a balloon.
4. The device of claim 1 wherein the expandable structure is an inflatable structure.
5. The device of claim 4 wherein the inflatable structure is a compliant balloon.
6. The device of claim 4 wherein the inflatable structure is a non-compliant balloon.
7. The device of claim 1 wherein the evacuator extends distally from the expandable member and terminates within the stomach.
8. The device of claim 1 further comprising a fastener that maintains the gastric reduction pouch.
9. The device of claim 8 wherein the fastener inwardly folds stomach tissue to fasten serosa tissue to serosa tissue of the stomach.
10. The device of claim 8 wherein the fastener comprises a cylindrically shaped member having opposed ends and tissue engaging arms radially extending from each of the opposed ends.
11. The device of claim 1 further comprising an endoscope that extends through the expandable member.
12. The device of claim 1 wherein the expandable member forms a spherically shaped ring when expanded.
13. The device of claim 12 wherein the spherically shaped ring includes an axial passageway and wherein the evacuator extends through the passageway.
14. A gastric reduction system, comprising:
an expandable structure, placeable in a stomach and, when expanded, occupying a fractional volume of the stomach;
an evacuator that deflates the stomach and draws the stomach to and around the expandable structure to form a gastric reduction pouch with stomach tissue; and
a fastener that is operable to maintain the gastric reduction pouch.
15. The system of claim 14 wherein the expandable structure is placeable in the stomach immediately adjacent and distal to an esophageal orifice associated with the stomach.
16. The system of claim 14 wherein the expandable structure comprises a balloon.
17. The device of claim 14 wherein the expandable structure is an inflatable structure.
18. The device of claim 17 wherein the inflatable structure is a compliant balloon.
19. The device of claim 17 wherein the inflatable structure is a non-compliant balloon.
20. The system of claim 14 wherein the evacuator extends distally from the expandable member and terminates within the stomach.
21. The system of claim 14 wherein the fastener inwardly folds stomach tissue to fasten serosa tissue to serosa tissue of the stomach.
22. The system of claim 21 wherein the fastener comprises a cylindrically shaped member having opposed ends and tissue engaging arms radially extending from each of the opposed ends.
23. The system of claim 21 wherein the fastener is carried by the evacuator.
24. The system of claim 14 further comprising an endoscope that extends through the expandable member.
25. The system of claim 14 wherein the expandable member forms a spherically shaped ring when expanded.
26. The system of claim 25 wherein the spherically shaped ring includes an axial passageway and wherein the evacuator extends through the passageway.
27. A method comprising:
positioning an expandable structure in a stomach of a patient;
expanding the expandable structure to occupy a portion of the stomach; and
drawing the stomach around the expanded expandable structure to form a gastric reduction pouch.
28. The method of claim 27 wherein the positioning step includes placing the expandable structure immediately distal to an esophageal orifice associated with the stomach.
29. The method of claim 27 wherein the expandable structure comprises a balloon and wherein the expanding step includes inflating the balloon.
30. The method of claim 27 wherein the deflating step includes evacuating the stomach.
31. The method of claim 27 wherein the deflating step includes feeding an evacuator into the stomach and evacuating the stomach.
32. The method of claim 27 including the further step of maintaining the gastric reduction pouch.
33. The method of claim 32 wherein the maintaining step includes inwardly folding stomach tissue to contact serosa tissue to serosa tissue to form a stomach.
34. The method of claim 33 wherein the maintaining step further includes fastening the inwardly folded stomach tissue together.
US10/686,427 2003-10-14 2003-10-14 Transesophageal gastric reduction device, system and method Abandoned US20050080444A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US10/686,427 US20050080444A1 (en) 2003-10-14 2003-10-14 Transesophageal gastric reduction device, system and method
CN200480030254.2A CN101076289A (en) 2003-10-14 2004-10-13 Transesophageal gastric reduction device, system and method
PCT/US2004/033905 WO2005037072A2 (en) 2003-10-14 2004-10-13 Transesophageal gastric reduction device, system andmethod
JP2006535653A JP2007514462A (en) 2003-10-14 2004-10-13 Transesophageal gastric reduction apparatus, system and method
EP04795109.0A EP1681984A4 (en) 2003-10-14 2004-10-13 Transesophageal gastric reduction device, system and method
US11/823,998 US20070260276A1 (en) 2003-10-14 2007-06-29 Transesophageal gastric reduction device, system and method
US13/069,992 US8430891B2 (en) 2003-10-14 2011-03-23 Transesophageal gastric reduction device, system and method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/686,427 US20050080444A1 (en) 2003-10-14 2003-10-14 Transesophageal gastric reduction device, system and method

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/823,998 Division US20070260276A1 (en) 2003-10-14 2007-06-29 Transesophageal gastric reduction device, system and method
US13/069,992 Continuation US8430891B2 (en) 2003-10-14 2011-03-23 Transesophageal gastric reduction device, system and method

Publications (1)

Publication Number Publication Date
US20050080444A1 true US20050080444A1 (en) 2005-04-14

Family

ID=34423290

Family Applications (3)

Application Number Title Priority Date Filing Date
US10/686,427 Abandoned US20050080444A1 (en) 2003-10-14 2003-10-14 Transesophageal gastric reduction device, system and method
US11/823,998 Abandoned US20070260276A1 (en) 2003-10-14 2007-06-29 Transesophageal gastric reduction device, system and method
US13/069,992 Expired - Lifetime US8430891B2 (en) 2003-10-14 2011-03-23 Transesophageal gastric reduction device, system and method

Family Applications After (2)

Application Number Title Priority Date Filing Date
US11/823,998 Abandoned US20070260276A1 (en) 2003-10-14 2007-06-29 Transesophageal gastric reduction device, system and method
US13/069,992 Expired - Lifetime US8430891B2 (en) 2003-10-14 2011-03-23 Transesophageal gastric reduction device, system and method

Country Status (5)

Country Link
US (3) US20050080444A1 (en)
EP (1) EP1681984A4 (en)
JP (1) JP2007514462A (en)
CN (1) CN101076289A (en)
WO (1) WO2005037072A2 (en)

Cited By (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040092892A1 (en) * 2002-11-01 2004-05-13 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US20050049718A1 (en) * 2002-11-01 2005-03-03 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
US20050080438A1 (en) * 2003-10-14 2005-04-14 Gary Weller System for tissue approximation and fixation
US20050177181A1 (en) * 2002-11-01 2005-08-11 Jonathan Kagan Devices and methods for treating morbid obesity
US20050240279A1 (en) * 2002-11-01 2005-10-27 Jonathan Kagan Gastrointestinal sleeve device and methods for treatment of morbid obesity
WO2005105003A1 (en) * 2004-04-26 2005-11-10 Synecor, Llc Restrictive and/or obstructive implant for inducing weight loss
US20050250980A1 (en) * 2004-05-07 2005-11-10 Usgi Medical Corp. Methods for performing gastroplasty
US20060015125A1 (en) * 2004-05-07 2006-01-19 Paul Swain Devices and methods for gastric surgery
US20060020247A1 (en) * 2002-11-01 2006-01-26 Jonathan Kagan Devices and methods for attaching an endolumenal gastrointestinal implant
US20060047289A1 (en) * 2004-08-27 2006-03-02 Roberto Fogel Endoscopic tissue apposition device and method of use
US20060167543A1 (en) * 1999-12-31 2006-07-27 Bailey Steven R Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US20060287734A1 (en) * 2001-08-27 2006-12-21 Synecor, Llc Positioning tools and methods for implanting medical devices
WO2007002822A2 (en) * 2005-06-29 2007-01-04 Endogastric Solutions, Inc. Apparatus and method for manipulating stomach tissue and treating gastroesophageal reflux disease
US20070010865A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Everting gastrointestinal sleeve
US20070276432A1 (en) * 2003-10-10 2007-11-29 Stack Richard S Devices and Methods for Retaining a Gastro-Esophageal Implant
US20080058887A1 (en) * 2006-04-25 2008-03-06 Bobby Griffin Methods and devices for gastrointestinal stimulation
US20080064957A1 (en) * 2006-09-07 2008-03-13 Spence Paul A Ultrasonic implant, systems and methods related to diverting material in blood flow away from the head
WO2008054617A1 (en) 2006-10-26 2008-05-08 Hourglass Technologies, Inc. Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue
US20080140110A1 (en) * 2006-12-12 2008-06-12 Spence Paul A Implant, systems and methods for physically diverting material in blood flow away from the head
US20080147095A1 (en) * 2000-05-19 2008-06-19 C. R. Bard, Inc Tissue capturing and suturing device and method
US20080172074A1 (en) * 2007-01-16 2008-07-17 Endogastric Solutions, Inc. Transesophageal gastric reduction method and device for practicing same
WO2007095096A3 (en) * 2006-02-10 2008-07-31 Endogastric Solutions Inc Transesophageal gastric reduction method and device for reducing the size of a previously formed gastric reduction pouch
US20080190989A1 (en) * 2005-10-03 2008-08-14 Crews Samuel T Endoscopic plication device and method
US20080208355A1 (en) * 2006-09-15 2008-08-28 Stack Richard S System and method for anchoring stomach implant
US20080215069A1 (en) * 2000-03-03 2008-09-04 C.R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
US20080294179A1 (en) * 2007-05-12 2008-11-27 Balbierz Daniel J Devices and methods for stomach partitioning
US20080312750A1 (en) * 2006-10-04 2008-12-18 Michael Laufer Methods and devices for reconfiguring a body organ
US20090012356A1 (en) * 2007-06-11 2009-01-08 Valen Tx, Inc. Endoscopic delivery devices and methods
US20090012544A1 (en) * 2007-06-08 2009-01-08 Valen Tx, Inc. Gastrointestinal bypass sleeve as an adjunct to bariatric surgery
US20090012553A1 (en) * 2007-06-08 2009-01-08 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US20090093837A1 (en) * 2007-10-09 2009-04-09 Wilson-Cook Medical Inc. Anastomosis plug for bariatric surgery
US20090125040A1 (en) * 2006-09-13 2009-05-14 Hambly Pablo R Tissue acquisition devices and methods
US20090171383A1 (en) * 2007-12-31 2009-07-02 David Cole Gastric space occupier systems and methods of use
US20090198266A1 (en) * 2008-02-01 2009-08-06 Jbm Medical Llc Devices and methods for abdominal surgery
US20090236389A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US20100100109A1 (en) * 2002-04-08 2010-04-22 Stack Richard S Method and apparatus for modifying the exit orifice of a satiation pouch
US7708684B2 (en) 2004-02-27 2010-05-04 Satiety, Inc. Methods and devices for reducing hollow organ volume
US20100116867A1 (en) * 2008-11-10 2010-05-13 Balbierz Daniel J Multi-fire stapling systems and methods for delivering arrays of staples
US7753870B2 (en) 2004-03-26 2010-07-13 Satiety, Inc. Systems and methods for treating obesity
US7753928B2 (en) 2000-11-03 2010-07-13 Satiety, Inc. Method and device for use in minimally invasive placement of intragastric devices
US7757924B2 (en) 2004-02-05 2010-07-20 Satiety, Inc. Single fold system for tissue approximation and fixation
US7789848B2 (en) 2002-10-23 2010-09-07 Satiety, Inc. Method and device for use in endoscopic organ procedures
US20100256775A1 (en) * 2009-04-03 2010-10-07 Metamodix, Inc. Modular gastrointestinal prostheses
US20100280529A1 (en) * 2009-05-04 2010-11-04 Barosense, Inc. Endoscopic implant system and method
US20100298631A1 (en) * 2001-08-27 2010-11-25 Stack Richard S Satiation devices and methods
US20100324572A1 (en) * 2007-02-06 2010-12-23 The Ohio State University Research Foundation Endolumenal Restriction Method and Apparatus
US7862574B2 (en) 2001-05-30 2011-01-04 Satiety, Inc. Obesity treatment tools and methods
US20110009690A1 (en) * 2009-07-10 2011-01-13 Metamodix, Inc. External Anchoring Configurations for Modular Gastrointestinal Prostheses
US7914543B2 (en) 2003-10-14 2011-03-29 Satiety, Inc. Single fold device for tissue fixation
US7918869B2 (en) 2004-05-07 2011-04-05 Usgi Medical, Inc. Methods and apparatus for performing endoluminal gastroplasty
US7947055B2 (en) 2002-08-30 2011-05-24 Ethicon Endo-Surgery, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
WO2011066446A2 (en) * 2009-11-25 2011-06-03 David Muller Systems and methods for reducing gastric volume
US8029455B2 (en) 2003-01-16 2011-10-04 Barosense, Inc. Satiation pouches and methods of use
US8062207B2 (en) 2002-08-07 2011-11-22 Ethicon Endo-Surgery, Inc. Intra-gastric fastening devices
US8092378B2 (en) 2004-11-17 2012-01-10 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8092482B2 (en) 2002-08-30 2012-01-10 Ethicon Endo-Surgery, Inc. Stented anchoring of gastric space-occupying devices
US8109895B2 (en) 2006-09-02 2012-02-07 Barosense, Inc. Intestinal sleeves and associated deployment systems and methods
US8206456B2 (en) 2003-10-10 2012-06-26 Barosense, Inc. Restrictive and/or obstructive implant system for inducing weight loss
US8211128B1 (en) * 2004-10-15 2012-07-03 Facundus Edward C Multifunction gastric bypass apparatus and method
US8231641B2 (en) 2003-04-16 2012-07-31 Ethicon Endo-Surgery, Inc. Method and devices for modifying the function of a body organ
US8252009B2 (en) 2004-03-09 2012-08-28 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8257365B2 (en) 2004-02-13 2012-09-04 Ethicon Endo-Surgery, Inc. Methods and devices for reducing hollow organ volume
US20120232577A1 (en) * 2009-10-21 2012-09-13 Allergan, Inc. Bariatric device and method for weight loss
US20120277525A1 (en) * 2009-10-09 2012-11-01 Flip Technologies Limited Device and a method for facilitating monitoring the cross-section of a gastric sleeve during formation thereof
US20130030351A1 (en) * 2009-04-03 2013-01-31 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US8449560B2 (en) 2004-03-09 2013-05-28 Satiety, Inc. Devices and methods for placement of partitions within a hollow body organ
US8469977B2 (en) 2005-10-03 2013-06-25 Barosense, Inc. Endoscopic plication device and method
US8628547B2 (en) 2004-03-09 2014-01-14 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8702641B2 (en) 2009-04-03 2014-04-22 Metamodix, Inc. Gastrointestinal prostheses having partial bypass configurations
US8726909B2 (en) 2006-01-27 2014-05-20 Usgi Medical, Inc. Methods and apparatus for revision of obesity procedures
US20140276991A1 (en) * 2013-03-15 2014-09-18 The Cleveland Clinic Foundation Gastric plication guide
US8956318B2 (en) 2012-05-31 2015-02-17 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9028511B2 (en) 2004-03-09 2015-05-12 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US9107727B2 (en) 2001-08-27 2015-08-18 Boston Scientific Scimed, Inc. Satiation devices and methods
US9278019B2 (en) 2009-04-03 2016-03-08 Metamodix, Inc Anchors and methods for intestinal bypass sleeves
US20160067074A1 (en) * 2014-09-05 2016-03-10 Standard Bariatrics, Inc. Sleeve Gastrectomy Calibration Tube And Method Of Using Same
US9381020B2 (en) * 2014-08-24 2016-07-05 Easy Notes Ltd. Pyloric obstruction device
US9451960B2 (en) 2012-05-31 2016-09-27 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9456825B2 (en) 2007-07-18 2016-10-04 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US9545249B2 (en) 2007-07-18 2017-01-17 Boston Scientific Scimed, Inc. Overtube introducer for use in endoscopic bariatric surgery
US9622897B1 (en) 2016-03-03 2017-04-18 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves
US9675489B2 (en) 2012-05-31 2017-06-13 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9724096B2 (en) 2014-03-29 2017-08-08 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US9757264B2 (en) 2013-03-13 2017-09-12 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9936953B2 (en) 2014-03-29 2018-04-10 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10159699B2 (en) 2013-01-15 2018-12-25 Metamodix, Inc. System and method for affecting intestinal microbial flora
US10278707B2 (en) 2013-12-17 2019-05-07 Standard Bariatrics, Inc. Resection line guide for a medical procedure and method of using same
US10285837B1 (en) 2015-09-16 2019-05-14 Standard Bariatrics, Inc. Systems and methods for measuring volume of potential sleeve in a sleeve gastrectomy
US10548597B2 (en) 2017-08-14 2020-02-04 Standard Bariatrics, Inc. Surgical stapling devices and methods of using same
US10751209B2 (en) 2016-05-19 2020-08-25 Metamodix, Inc. Pyloric anchor retrieval tools and methods
US11173060B2 (en) 2019-11-04 2021-11-16 Standard Bariatrics, Inc. Systems and methods of performing surgery using Laplace's law tension retraction during surgery
US11452574B1 (en) 2021-03-23 2022-09-27 Standard Bariatrics, Inc. Systems and methods for preventing tissue migration in surgical staplers

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7942898B2 (en) 2002-12-11 2011-05-17 Usgi Medical, Inc. Delivery systems and methods for gastric reduction
US7942884B2 (en) 2002-12-11 2011-05-17 Usgi Medical, Inc. Methods for reduction of a gastric lumen
US8425539B2 (en) 2004-04-12 2013-04-23 Xlumena, Inc. Luminal structure anchoring devices and methods
WO2006062996A2 (en) 2004-12-08 2006-06-15 Kenneth Binmoeller Method and apparatus for performing needle guided interventions
US8784437B2 (en) 2005-06-09 2014-07-22 Xlumena, Inc. Methods and devices for endosonography-guided fundoplexy
US8777967B2 (en) 2005-06-09 2014-07-15 Xlumena, Inc. Methods and devices for anchoring to tissue
US8221438B2 (en) * 2006-02-17 2012-07-17 Ethicon Endo-Surgery, Inc. Lumen reduction methods and devices
US8870916B2 (en) 2006-07-07 2014-10-28 USGI Medical, Inc Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use
HUE054386T2 (en) * 2008-01-29 2021-09-28 Implantica Patent Ltd Apparatus for treating obesity
US8454632B2 (en) 2008-05-12 2013-06-04 Xlumena, Inc. Tissue anchor for securing tissue layers
US9381041B2 (en) 2009-04-21 2016-07-05 Xlumena, Inc. Methods and devices for access across adjacent tissue layers
US9364259B2 (en) 2009-04-21 2016-06-14 Xlumena, Inc. System and method for delivering expanding trocar through a sheath
EP2434961B1 (en) 2009-05-29 2015-01-14 Xlumena, Inc. Apparatus and method for deploying stent across adjacent tissue layers
EP2958527B1 (en) 2013-02-21 2020-07-22 Boston Scientific Scimed, Inc. Devices for forming an anastomosis

Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246893A (en) * 1978-07-05 1981-01-27 Daniel Berson Inflatable gastric device for treating obesity
US4592339A (en) * 1985-06-12 1986-06-03 Mentor Corporation Gastric banding device
US4648383A (en) * 1985-01-11 1987-03-10 Angelchik Jean P Peroral apparatus for morbid obesity treatment
US4723547A (en) * 1985-05-07 1988-02-09 C. R. Bard, Inc. Anti-obesity balloon placement system
US5234454A (en) * 1991-08-05 1993-08-10 Akron City Hospital Percutaneous intragastric balloon catheter and method for controlling body weight therewith
US5306300A (en) * 1992-09-22 1994-04-26 Berry H Lee Tubular digestive screen
US5345949A (en) * 1992-09-02 1994-09-13 Shlain Leonard M Methods for use in surgical gastroplastic procedure
US5431173A (en) * 1991-05-29 1995-07-11 Origin Medsystems, Inc. Method and apparatus for body structure manipulation and dissection
US5601604A (en) * 1993-05-27 1997-02-11 Inamed Development Co. Universal gastric band
US5658272A (en) * 1992-09-15 1997-08-19 Hasson; Harrith M. Surgical instrument support and method of using the same
US5868141A (en) * 1997-05-14 1999-02-09 Ellias; Yakub A. Endoscopic stomach insert for treating obesity and method for use
US6129685A (en) * 1994-02-09 2000-10-10 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
US6210347B1 (en) * 1998-08-13 2001-04-03 Peter Forsell Remote control food intake restriction device
US6254642B1 (en) * 1997-12-09 2001-07-03 Thomas V. Taylor Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US20010011179A1 (en) * 1999-09-17 2001-08-02 Scimed Life System, Inc. Balloon with reversed cones
US20010011543A1 (en) * 1999-08-12 2001-08-09 Peter Forsell Controlled food flow in a patient
US20020062130A1 (en) * 1999-11-18 2002-05-23 Jugenheimer Kristen A. Apparatus and method for compressing body tissue
US20030023230A1 (en) * 1998-02-03 2003-01-30 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
US20030065359A1 (en) * 2001-05-30 2003-04-03 Gary Weller Overtube apparatus for insertion into a body
US20040148034A1 (en) * 2002-11-01 2004-07-29 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US6773440B2 (en) * 2002-07-02 2004-08-10 Satiety, Inc. Method and device for use in tissue approximation and fixation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416267A (en) * 1981-12-10 1983-11-22 Garren Lloyd R Method and apparatus for treating obesity
US5549621A (en) * 1993-05-14 1996-08-27 Byron C. Sutherland Apparatus and method for performing vertical banded gastroplasty
US6113612A (en) * 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
US7160312B2 (en) * 1999-06-25 2007-01-09 Usgi Medical, Inc. Implantable artificial partition and methods of use
US6676698B2 (en) * 2000-06-26 2004-01-13 Rex Medicol, L.P. Vascular device with valve for approximating vessel wall
AU2001286704A1 (en) * 2000-08-24 2002-03-04 Surgical Connections, Inc. Surgical stabilizer devices and methods
US6558400B2 (en) * 2001-05-30 2003-05-06 Satiety, Inc. Obesity treatment tools and methods
US7115136B2 (en) * 2001-06-20 2006-10-03 Park Medical Llc Anastomotic device
WO2003061480A1 (en) * 2001-10-20 2003-07-31 Applied Medical Resources Corporation Wound retraction apparatus and method
US6981978B2 (en) * 2002-08-30 2006-01-03 Satiety, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US20050247320A1 (en) * 2003-10-10 2005-11-10 Stack Richard S Devices and methods for retaining a gastro-esophageal implant

Patent Citations (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246893A (en) * 1978-07-05 1981-01-27 Daniel Berson Inflatable gastric device for treating obesity
US4648383A (en) * 1985-01-11 1987-03-10 Angelchik Jean P Peroral apparatus for morbid obesity treatment
US4723547A (en) * 1985-05-07 1988-02-09 C. R. Bard, Inc. Anti-obesity balloon placement system
US4592339A (en) * 1985-06-12 1986-06-03 Mentor Corporation Gastric banding device
US5431173A (en) * 1991-05-29 1995-07-11 Origin Medsystems, Inc. Method and apparatus for body structure manipulation and dissection
US5234454A (en) * 1991-08-05 1993-08-10 Akron City Hospital Percutaneous intragastric balloon catheter and method for controlling body weight therewith
US5345949A (en) * 1992-09-02 1994-09-13 Shlain Leonard M Methods for use in surgical gastroplastic procedure
US5658272A (en) * 1992-09-15 1997-08-19 Hasson; Harrith M. Surgical instrument support and method of using the same
US5306300A (en) * 1992-09-22 1994-04-26 Berry H Lee Tubular digestive screen
US5601604A (en) * 1993-05-27 1997-02-11 Inamed Development Co. Universal gastric band
US6129685A (en) * 1994-02-09 2000-10-10 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
US5868141A (en) * 1997-05-14 1999-02-09 Ellias; Yakub A. Endoscopic stomach insert for treating obesity and method for use
US6254642B1 (en) * 1997-12-09 2001-07-03 Thomas V. Taylor Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US20030023230A1 (en) * 1998-02-03 2003-01-30 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
US6210347B1 (en) * 1998-08-13 2001-04-03 Peter Forsell Remote control food intake restriction device
US20010011543A1 (en) * 1999-08-12 2001-08-09 Peter Forsell Controlled food flow in a patient
US20010011179A1 (en) * 1999-09-17 2001-08-02 Scimed Life System, Inc. Balloon with reversed cones
US20020062130A1 (en) * 1999-11-18 2002-05-23 Jugenheimer Kristen A. Apparatus and method for compressing body tissue
US20030065359A1 (en) * 2001-05-30 2003-04-03 Gary Weller Overtube apparatus for insertion into a body
US6773440B2 (en) * 2002-07-02 2004-08-10 Satiety, Inc. Method and device for use in tissue approximation and fixation
US20040148034A1 (en) * 2002-11-01 2004-07-29 Jonathan Kagan Apparatus and methods for treatment of morbid obesity

Cited By (258)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8992597B2 (en) 1999-12-31 2015-03-31 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US9421100B2 (en) 1999-12-31 2016-08-23 ABPS Venture One, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US7799069B2 (en) * 1999-12-31 2010-09-21 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US20060167543A1 (en) * 1999-12-31 2006-07-27 Bailey Steven R Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US8152821B2 (en) 2000-03-03 2012-04-10 C.R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
US20080215069A1 (en) * 2000-03-03 2008-09-04 C.R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
US20080147095A1 (en) * 2000-05-19 2008-06-19 C. R. Bard, Inc Tissue capturing and suturing device and method
US8551120B2 (en) 2000-05-19 2013-10-08 C.R. Bard, Inc. Tissue capturing and suturing device and method
US8388632B2 (en) 2000-05-19 2013-03-05 C.R. Bard, Inc. Tissue capturing and suturing device and method
US7753928B2 (en) 2000-11-03 2010-07-13 Satiety, Inc. Method and device for use in minimally invasive placement of intragastric devices
US8080025B2 (en) 2001-05-30 2011-12-20 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8137366B2 (en) 2001-05-30 2012-03-20 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8137367B2 (en) 2001-05-30 2012-03-20 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8123765B2 (en) 2001-05-30 2012-02-28 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8419755B2 (en) 2001-05-30 2013-04-16 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8080022B2 (en) 2001-05-30 2011-12-20 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8613749B2 (en) 2001-05-30 2013-12-24 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US8794243B2 (en) 2001-05-30 2014-08-05 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US7862574B2 (en) 2001-05-30 2011-01-04 Satiety, Inc. Obesity treatment tools and methods
US8075577B2 (en) 2001-05-30 2011-12-13 Ethicon Endo-Surgery, Inc. Obesity treatment tools and methods
US7909838B2 (en) 2001-05-30 2011-03-22 Satiety, Inc. Obesity treatment tools and methods
US8845753B2 (en) 2001-08-27 2014-09-30 Boston Scientific Scimed, Inc. Satiation devices and methods
US9107727B2 (en) 2001-08-27 2015-08-18 Boston Scientific Scimed, Inc. Satiation devices and methods
US8784354B2 (en) 2001-08-27 2014-07-22 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
US7892292B2 (en) 2001-08-27 2011-02-22 Synecor, Llc Positioning tools and methods for implanting medical devices
US20100298631A1 (en) * 2001-08-27 2010-11-25 Stack Richard S Satiation devices and methods
US9358144B2 (en) 2001-08-27 2016-06-07 Boston Scientific Scimed, Inc. Gastrointestinal implants
US9254214B2 (en) 2001-08-27 2016-02-09 Boston Scientific Scimed, Inc. Satiation devices and methods
US20060287734A1 (en) * 2001-08-27 2006-12-21 Synecor, Llc Positioning tools and methods for implanting medical devices
US8568488B2 (en) 2001-08-27 2013-10-29 Boston Scientific Scimed, Inc. Satiation devices and methods
US9844453B2 (en) 2001-08-27 2017-12-19 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
US9180036B2 (en) 2001-08-27 2015-11-10 Boston Scientific Scimed, Inc. Methods for implanting medical devices
US9138340B2 (en) 2001-08-27 2015-09-22 Boston Scientific Scimed, Inc. Gastro-esophageal implants
US9788984B2 (en) 2001-08-27 2017-10-17 Boston Scientific Scimed, Inc. Satiation devices and methods
US9872786B2 (en) 2001-08-27 2018-01-23 Boston Scientific Scimed, Inc. Gastro-esophageal implants
US10080677B2 (en) 2001-08-27 2018-09-25 Boston Scientific Scimed, Inc. Satiation devices and methods
US8992457B2 (en) 2001-08-27 2015-03-31 Boston Scientific Scimed, Inc. Gastrointestinal implants
US20100100109A1 (en) * 2002-04-08 2010-04-22 Stack Richard S Method and apparatus for modifying the exit orifice of a satiation pouch
US8337566B2 (en) 2002-04-08 2012-12-25 Barosense, Inc. Method and apparatus for modifying the exit orifice of a satiation pouch
US8062207B2 (en) 2002-08-07 2011-11-22 Ethicon Endo-Surgery, Inc. Intra-gastric fastening devices
US8083757B2 (en) 2002-08-30 2011-12-27 Ethicon Endo-Surgery, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US7947055B2 (en) 2002-08-30 2011-05-24 Ethicon Endo-Surgery, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US8092482B2 (en) 2002-08-30 2012-01-10 Ethicon Endo-Surgery, Inc. Stented anchoring of gastric space-occupying devices
US8083756B2 (en) 2002-08-30 2011-12-27 Ethicon Endo-Surgery, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US8147441B2 (en) 2002-10-23 2012-04-03 Ethicon Endo-Surgery, Inc. Method and device for use in endoscopic organ procedures
US8801650B2 (en) 2002-10-23 2014-08-12 Ethicon Endo-Surgery, Inc. Method and device for use in endoscopic organ procedures
US7789848B2 (en) 2002-10-23 2010-09-07 Satiety, Inc. Method and device for use in endoscopic organ procedures
US20050240279A1 (en) * 2002-11-01 2005-10-27 Jonathan Kagan Gastrointestinal sleeve device and methods for treatment of morbid obesity
US20070010794A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Devices and methods for endolumenal gastrointestinal bypass
US20060206064A1 (en) * 2002-11-01 2006-09-14 Jonathan Kagan Methods of adjusting therapy in a patient having an endolumenal bypass to treat obesity
US20040092892A1 (en) * 2002-11-01 2004-05-13 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US20090149871A9 (en) * 2002-11-01 2009-06-11 Jonathan Kagan Devices and methods for treating morbid obesity
US8070743B2 (en) 2002-11-01 2011-12-06 Valentx, Inc. Devices and methods for attaching an endolumenal gastrointestinal implant
US8012140B1 (en) 2002-11-01 2011-09-06 Valentx, Inc. Methods of transmural attachment in the gastrointestinal system
US8182459B2 (en) 2002-11-01 2012-05-22 Valentx, Inc. Devices and methods for endolumenal gastrointestinal bypass
US9839546B2 (en) 2002-11-01 2017-12-12 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US20060293742A1 (en) * 2002-11-01 2006-12-28 Mitchell Dann Cuff and sleeve system for gastrointestinal bypass
US20070010865A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Everting gastrointestinal sleeve
US20060020247A1 (en) * 2002-11-01 2006-01-26 Jonathan Kagan Devices and methods for attaching an endolumenal gastrointestinal implant
US8968270B2 (en) 2002-11-01 2015-03-03 Valentx, Inc. Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment
US20070010864A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Gastrointestinal implant system
US9060844B2 (en) 2002-11-01 2015-06-23 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US7892214B2 (en) 2002-11-01 2011-02-22 Valentx, Inc. Attachment system for transmural attachment at the gastroesophageal junction
US8012135B2 (en) 2002-11-01 2011-09-06 Valentx, Inc. Attachment cuff for gastrointestinal implant
US10350101B2 (en) 2002-11-01 2019-07-16 Valentx, Inc. Devices and methods for endolumenal gastrointestinal bypass
US7794447B2 (en) 2002-11-01 2010-09-14 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
US20050049718A1 (en) * 2002-11-01 2005-03-03 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
US9561127B2 (en) 2002-11-01 2017-02-07 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US20070198074A1 (en) * 2002-11-01 2007-08-23 Mitchell Dann Devices and methods for endolumenal gastrointestinal bypass
US7837669B2 (en) 2002-11-01 2010-11-23 Valentx, Inc. Devices and methods for endolumenal gastrointestinal bypass
US7220284B2 (en) 2002-11-01 2007-05-22 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
US7846138B2 (en) 2002-11-01 2010-12-07 Valentx, Inc. Cuff and sleeve system for gastrointestinal bypass
US20050177181A1 (en) * 2002-11-01 2005-08-11 Jonathan Kagan Devices and methods for treating morbid obesity
US20050096750A1 (en) * 2002-11-01 2005-05-05 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US8029455B2 (en) 2003-01-16 2011-10-04 Barosense, Inc. Satiation pouches and methods of use
US8231641B2 (en) 2003-04-16 2012-07-31 Ethicon Endo-Surgery, Inc. Method and devices for modifying the function of a body organ
US8784500B2 (en) 2003-10-10 2014-07-22 Boston Scientific Scimed, Inc. Devices and methods for retaining a gastro-esophageal implant
US9445791B2 (en) 2003-10-10 2016-09-20 Boston Scientific Scimed, Inc. Systems and methods related to gastro-esophageal implants
US10285836B2 (en) 2003-10-10 2019-05-14 Boston Scientific Scimed, Inc. Systems and methods related to gastro-esophageal implants
US20070276432A1 (en) * 2003-10-10 2007-11-29 Stack Richard S Devices and Methods for Retaining a Gastro-Esophageal Implant
US9248038B2 (en) 2003-10-10 2016-02-02 Boston Scientific Scimed, Inc. Methods for retaining a gastro-esophageal implant
US9180035B2 (en) 2003-10-10 2015-11-10 Boston Scientific Scimed, Inc. Devices and methods for retaining a gastro-esophageal implant
US8206456B2 (en) 2003-10-10 2012-06-26 Barosense, Inc. Restrictive and/or obstructive implant system for inducing weight loss
US8357174B2 (en) 2003-10-14 2013-01-22 Roth Alex T Single fold device for tissue fixation
US9186268B2 (en) 2003-10-14 2015-11-17 Ethicon Endo-Surgery, Inc. Single fold device for tissue fixation
US8007505B2 (en) 2003-10-14 2011-08-30 Ethicon Eado-Surgery, Inc. System for tissue approximation and fixation
US7914543B2 (en) 2003-10-14 2011-03-29 Satiety, Inc. Single fold device for tissue fixation
US20050080438A1 (en) * 2003-10-14 2005-04-14 Gary Weller System for tissue approximation and fixation
US7757924B2 (en) 2004-02-05 2010-07-20 Satiety, Inc. Single fold system for tissue approximation and fixation
US8590761B2 (en) 2004-02-05 2013-11-26 Ethicon Endo-Surgery, Inc. Single fold system for tissue approximation and fixation
US8257365B2 (en) 2004-02-13 2012-09-04 Ethicon Endo-Surgery, Inc. Methods and devices for reducing hollow organ volume
US8828025B2 (en) 2004-02-13 2014-09-09 Ethicon Endo-Surgery, Inc. Methods and devices for reducing hollow organ volume
US8057384B2 (en) 2004-02-27 2011-11-15 Ethicon Endo-Surgery, Inc. Methods and devices for reducing hollow organ volume
US7708684B2 (en) 2004-02-27 2010-05-04 Satiety, Inc. Methods and devices for reducing hollow organ volume
US8449560B2 (en) 2004-03-09 2013-05-28 Satiety, Inc. Devices and methods for placement of partitions within a hollow body organ
US8628547B2 (en) 2004-03-09 2014-01-14 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8252009B2 (en) 2004-03-09 2012-08-28 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US9028511B2 (en) 2004-03-09 2015-05-12 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US7753870B2 (en) 2004-03-26 2010-07-13 Satiety, Inc. Systems and methods for treating obesity
WO2005105003A1 (en) * 2004-04-26 2005-11-10 Synecor, Llc Restrictive and/or obstructive implant for inducing weight loss
US8241202B2 (en) 2004-04-26 2012-08-14 Barosense, Inc. Restrictive and/or obstructive implant for inducing weight loss
US7717843B2 (en) 2004-04-26 2010-05-18 Barosense, Inc. Restrictive and/or obstructive implant for inducing weight loss
US20050261712A1 (en) * 2004-04-26 2005-11-24 Balbierz Daniel J Restrictive and/or obstructive implant for inducing weight loss
US20100204719A1 (en) * 2004-04-26 2010-08-12 Balbierz Daniel J Restrictive and/or obstructive implant for inducing weight loss
US10098773B2 (en) 2004-04-26 2018-10-16 Boston Scientific Scimed, Inc. Restrictive and/or obstructive implant for inducing weight loss
US20090209984A1 (en) * 2004-05-07 2009-08-20 Usgi Medical, Inc. Methods for performing gastroplasty
US20050250980A1 (en) * 2004-05-07 2005-11-10 Usgi Medical Corp. Methods for performing gastroplasty
US7918869B2 (en) 2004-05-07 2011-04-05 Usgi Medical, Inc. Methods and apparatus for performing endoluminal gastroplasty
US7520884B2 (en) * 2004-05-07 2009-04-21 Usgi Medical Inc. Methods for performing gastroplasty
US20060015125A1 (en) * 2004-05-07 2006-01-19 Paul Swain Devices and methods for gastric surgery
US8172857B2 (en) 2004-08-27 2012-05-08 Davol, Inc. Endoscopic tissue apposition device and method of use
US20060047289A1 (en) * 2004-08-27 2006-03-02 Roberto Fogel Endoscopic tissue apposition device and method of use
US9149270B2 (en) 2004-08-27 2015-10-06 Davol, Inc. (a C.R. Bard Company) Endoscopic tissue apposition device and method of use
US8211128B1 (en) * 2004-10-15 2012-07-03 Facundus Edward C Multifunction gastric bypass apparatus and method
US8403839B2 (en) 2004-11-17 2013-03-26 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8795166B2 (en) 2004-11-17 2014-08-05 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8403838B2 (en) 2004-11-17 2013-03-26 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8784306B2 (en) 2004-11-17 2014-07-22 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8454503B2 (en) 2004-11-17 2013-06-04 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8939902B2 (en) 2004-11-17 2015-01-27 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US8092378B2 (en) 2004-11-17 2012-01-10 Ethicon Endo-Surgery, Inc. Remote tissue retraction device
US10327793B2 (en) * 2005-06-29 2019-06-25 Endogastric Solutions, Inc. Apparatus and method for manipulating stomach tissue and treating gastroesophageal reflux disease
WO2007002822A3 (en) * 2005-06-29 2007-05-18 Endogastric Solutions Inc Apparatus and method for manipulating stomach tissue and treating gastroesophageal reflux disease
WO2007002822A2 (en) * 2005-06-29 2007-01-04 Endogastric Solutions, Inc. Apparatus and method for manipulating stomach tissue and treating gastroesophageal reflux disease
US20160089136A1 (en) * 2005-06-29 2016-03-31 Endogastric Solutions, Inc. Apparatus and method for manipulating stomach tissue and treating gastroesophageal reflux disease
US9055942B2 (en) 2005-10-03 2015-06-16 Boston Scienctific Scimed, Inc. Endoscopic plication devices and methods
US20080190989A1 (en) * 2005-10-03 2008-08-14 Crews Samuel T Endoscopic plication device and method
US8469977B2 (en) 2005-10-03 2013-06-25 Barosense, Inc. Endoscopic plication device and method
US10299796B2 (en) 2005-10-03 2019-05-28 Boston Scientific Scimed, Inc. Endoscopic plication devices and methods
US8726909B2 (en) 2006-01-27 2014-05-20 Usgi Medical, Inc. Methods and apparatus for revision of obesity procedures
WO2007095096A3 (en) * 2006-02-10 2008-07-31 Endogastric Solutions Inc Transesophageal gastric reduction method and device for reducing the size of a previously formed gastric reduction pouch
US20080058887A1 (en) * 2006-04-25 2008-03-06 Bobby Griffin Methods and devices for gastrointestinal stimulation
US7881797B2 (en) 2006-04-25 2011-02-01 Valentx, Inc. Methods and devices for gastrointestinal stimulation
US8109895B2 (en) 2006-09-02 2012-02-07 Barosense, Inc. Intestinal sleeves and associated deployment systems and methods
US9687334B2 (en) 2006-09-02 2017-06-27 Boston Scientific Scimed, Inc. Intestinal sleeves and associated deployment systems and methods
US20080064957A1 (en) * 2006-09-07 2008-03-13 Spence Paul A Ultrasonic implant, systems and methods related to diverting material in blood flow away from the head
US20110224582A1 (en) * 2006-09-07 2011-09-15 Spence Paul A Methods related to diverting material in blood flow away from the head
US20090125040A1 (en) * 2006-09-13 2009-05-14 Hambly Pablo R Tissue acquisition devices and methods
US9314361B2 (en) 2006-09-15 2016-04-19 Boston Scientific Scimed, Inc. System and method for anchoring stomach implant
US20080208355A1 (en) * 2006-09-15 2008-08-28 Stack Richard S System and method for anchoring stomach implant
US8882789B2 (en) 2006-10-04 2014-11-11 Ethicon Endo-Surgery, Inc. Methods and systems for tissue manipulation
US8926641B2 (en) * 2006-10-04 2015-01-06 Ethicon Endo-Surgery, Inc. Methods and devices for reconfiguring a body organ
US20080312750A1 (en) * 2006-10-04 2008-12-18 Michael Laufer Methods and devices for reconfiguring a body organ
US20090018389A1 (en) * 2006-10-04 2009-01-15 Michael Laufer Methods and systems for tissue manipulation
US20090062820A1 (en) * 2006-10-26 2009-03-05 Hourglass Technologies, Inc. Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue
US8100925B2 (en) 2006-10-26 2012-01-24 Hourglass Technologies, Inc. Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue
WO2008054617A1 (en) 2006-10-26 2008-05-08 Hourglass Technologies, Inc. Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue
US20080255592A1 (en) * 2006-10-26 2008-10-16 Hourglass Technologies, Inc. Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue
US8257374B2 (en) * 2006-10-26 2012-09-04 Hourglass Technologies, Inc. Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue
US8083758B2 (en) * 2006-10-26 2011-12-27 Hourglass Technologies, Inc. Methods and devices for treating obesity and GERD by intussuscepting a portion of stomach tissue
US20090192531A1 (en) * 2006-10-26 2009-07-30 Hourglass Technologies, Inc. Methods and devices for treating obesity and gerd by intussuscepting a portion of stomach tissue
US20080140110A1 (en) * 2006-12-12 2008-06-12 Spence Paul A Implant, systems and methods for physically diverting material in blood flow away from the head
US20080172074A1 (en) * 2007-01-16 2008-07-17 Endogastric Solutions, Inc. Transesophageal gastric reduction method and device for practicing same
US8591533B2 (en) * 2007-02-06 2013-11-26 The Ohio State University Research Foundation Endolumenal restriction method and apparatus
US20100324572A1 (en) * 2007-02-06 2010-12-23 The Ohio State University Research Foundation Endolumenal Restriction Method and Apparatus
US20080294179A1 (en) * 2007-05-12 2008-11-27 Balbierz Daniel J Devices and methods for stomach partitioning
US20090012553A1 (en) * 2007-06-08 2009-01-08 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US8182441B2 (en) 2007-06-08 2012-05-22 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US20090012544A1 (en) * 2007-06-08 2009-01-08 Valen Tx, Inc. Gastrointestinal bypass sleeve as an adjunct to bariatric surgery
US20090012356A1 (en) * 2007-06-11 2009-01-08 Valen Tx, Inc. Endoscopic delivery devices and methods
US9456825B2 (en) 2007-07-18 2016-10-04 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US9545249B2 (en) 2007-07-18 2017-01-17 Boston Scientific Scimed, Inc. Overtube introducer for use in endoscopic bariatric surgery
US10537456B2 (en) 2007-07-18 2020-01-21 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US20090093837A1 (en) * 2007-10-09 2009-04-09 Wilson-Cook Medical Inc. Anastomosis plug for bariatric surgery
US20090171383A1 (en) * 2007-12-31 2009-07-02 David Cole Gastric space occupier systems and methods of use
US8945167B2 (en) 2007-12-31 2015-02-03 Boston Scientific Scimed, Inc. Gastric space occupier systems and methods of use
US20090198266A1 (en) * 2008-02-01 2009-08-06 Jbm Medical Llc Devices and methods for abdominal surgery
US7913892B2 (en) 2008-03-18 2011-03-29 Barosense, Inc. Endoscopic stapling devices and methods
US20090236396A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US20090236391A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US7909219B2 (en) 2008-03-18 2011-03-22 Barosense, Inc. Endoscopic stapling devices and methods
US20090236390A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US9636114B2 (en) 2008-03-18 2017-05-02 Boston Scientific Scimed, Inc. Endoscopic stapling devices
US20090236389A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US7909223B2 (en) 2008-03-18 2011-03-22 Barosense, Inc. Endoscopic stapling devices and methods
US8020741B2 (en) 2008-03-18 2011-09-20 Barosense, Inc. Endoscopic stapling devices and methods
US20090236397A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US8864008B2 (en) 2008-03-18 2014-10-21 Boston Scientific Scimed, Inc. Endoscopic stapling devices and methods
US7922062B2 (en) 2008-03-18 2011-04-12 Barosense, Inc. Endoscopic stapling devices and methods
US20090236400A1 (en) * 2008-03-18 2009-09-24 David Cole Endoscopic stapling devices and methods
US7909222B2 (en) 2008-03-18 2011-03-22 Barosense, Inc. Endoscopic stapling devices and methods
US20100116867A1 (en) * 2008-11-10 2010-05-13 Balbierz Daniel J Multi-fire stapling systems and methods for delivering arrays of staples
US10368862B2 (en) 2008-11-10 2019-08-06 Boston Scientific Scimed, Inc. Multi-fire stapling methods
US9451956B2 (en) 2008-11-10 2016-09-27 Boston Scientific Scimed, Inc. Multi-fire stapling systems
US7934631B2 (en) 2008-11-10 2011-05-03 Barosense, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US8747421B2 (en) 2008-11-10 2014-06-10 Boston Scientific Scimed, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US11202627B2 (en) 2008-11-10 2021-12-21 Boston Scientific Scimed, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US9044300B2 (en) 2009-04-03 2015-06-02 Metamodix, Inc. Gastrointestinal prostheses
US9962278B2 (en) 2009-04-03 2018-05-08 Metamodix, Inc. Modular gastrointestinal prostheses
US8211186B2 (en) 2009-04-03 2012-07-03 Metamodix, Inc. Modular gastrointestinal prostheses
US9278019B2 (en) 2009-04-03 2016-03-08 Metamodix, Inc Anchors and methods for intestinal bypass sleeves
US8702641B2 (en) 2009-04-03 2014-04-22 Metamodix, Inc. Gastrointestinal prostheses having partial bypass configurations
US9173760B2 (en) * 2009-04-03 2015-11-03 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US10322021B2 (en) 2009-04-03 2019-06-18 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US20100256775A1 (en) * 2009-04-03 2010-10-07 Metamodix, Inc. Modular gastrointestinal prostheses
US20130030351A1 (en) * 2009-04-03 2013-01-31 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US20100280529A1 (en) * 2009-05-04 2010-11-04 Barosense, Inc. Endoscopic implant system and method
US8961539B2 (en) 2009-05-04 2015-02-24 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US20110009690A1 (en) * 2009-07-10 2011-01-13 Metamodix, Inc. External Anchoring Configurations for Modular Gastrointestinal Prostheses
US8282598B2 (en) 2009-07-10 2012-10-09 Metamodix, Inc. External anchoring configurations for modular gastrointestinal prostheses
US8702642B2 (en) 2009-07-10 2014-04-22 Metamodix, Inc. External anchoring configurations for modular gastrointestinal prostheses
US20120277525A1 (en) * 2009-10-09 2012-11-01 Flip Technologies Limited Device and a method for facilitating monitoring the cross-section of a gastric sleeve during formation thereof
US9439633B2 (en) * 2009-10-09 2016-09-13 Flip Technologies Limited Device and a method for facilitating monitoring the cross-section of a gastric sleeve during formation thereof
US10111771B2 (en) 2009-10-21 2018-10-30 Apollo Endosurgery Us, Inc. Bariatric device and method for weight loss
US9072579B2 (en) * 2009-10-21 2015-07-07 Apollo Endosurgery, Inc. Bariatric device and method for weight loss
US20120232577A1 (en) * 2009-10-21 2012-09-13 Allergan, Inc. Bariatric device and method for weight loss
WO2011066446A2 (en) * 2009-11-25 2011-06-03 David Muller Systems and methods for reducing gastric volume
WO2011066446A3 (en) * 2009-11-25 2011-10-20 David Muller Systems and methods for reducing gastric volume
US9566181B2 (en) 2012-05-31 2017-02-14 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9050168B2 (en) 2012-05-31 2015-06-09 Valentx, Inc. Devices and methods for gastrointestinal bypass
US8956318B2 (en) 2012-05-31 2015-02-17 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9451960B2 (en) 2012-05-31 2016-09-27 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9681975B2 (en) 2012-05-31 2017-06-20 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9675489B2 (en) 2012-05-31 2017-06-13 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9173759B2 (en) 2012-05-31 2015-11-03 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9039649B2 (en) 2012-05-31 2015-05-26 Valentx, Inc. Devices and methods for gastrointestinal bypass
US11793839B2 (en) 2013-01-15 2023-10-24 Metamodix, Inc. System and method for affecting intestinal microbial flora
US10159699B2 (en) 2013-01-15 2018-12-25 Metamodix, Inc. System and method for affecting intestinal microbial flora
US9757264B2 (en) 2013-03-13 2017-09-12 Valentx, Inc. Devices and methods for gastrointestinal bypass
US20140276991A1 (en) * 2013-03-15 2014-09-18 The Cleveland Clinic Foundation Gastric plication guide
US10278707B2 (en) 2013-12-17 2019-05-07 Standard Bariatrics, Inc. Resection line guide for a medical procedure and method of using same
US10987108B2 (en) 2013-12-17 2021-04-27 Standard Bariatrics, Inc. Resection line guide for a medical procedure and method of using same
US11911044B2 (en) 2013-12-17 2024-02-27 Standard Bariatrics, Inc. Resection line guide for a medical procedure and method of using same
US9724096B2 (en) 2014-03-29 2017-08-08 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11812962B2 (en) 2014-03-29 2023-11-14 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10278699B2 (en) 2014-03-29 2019-05-07 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10231734B2 (en) 2014-03-29 2019-03-19 Standard Bariatrics, Inc. Compression mechanism for surgical stapling devices
US10405860B2 (en) 2014-03-29 2019-09-10 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10441283B1 (en) 2014-03-29 2019-10-15 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11633184B2 (en) 2014-03-29 2023-04-25 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US9936953B2 (en) 2014-03-29 2018-04-10 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10542986B2 (en) 2014-03-29 2020-01-28 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11096686B2 (en) 2014-03-29 2021-08-24 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10624638B2 (en) 2014-03-29 2020-04-21 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11510672B2 (en) 2014-03-29 2022-11-29 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11717295B2 (en) 2014-03-29 2023-08-08 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US9381020B2 (en) * 2014-08-24 2016-07-05 Easy Notes Ltd. Pyloric obstruction device
US10470911B2 (en) * 2014-09-05 2019-11-12 Standard Bariatrics, Inc. Sleeve gastrectomy calibration tube and method of using same
US20160067074A1 (en) * 2014-09-05 2016-03-10 Standard Bariatrics, Inc. Sleeve Gastrectomy Calibration Tube And Method Of Using Same
US10285837B1 (en) 2015-09-16 2019-05-14 Standard Bariatrics, Inc. Systems and methods for measuring volume of potential sleeve in a sleeve gastrectomy
US11324620B2 (en) 2015-09-16 2022-05-10 Standard Bariatrics, Inc. Systems and methods for measuring volume of potential sleeve in a sleeve gastrectomy
US9622897B1 (en) 2016-03-03 2017-04-18 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves
US10729573B2 (en) 2016-03-03 2020-08-04 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves
US20170252195A1 (en) 2016-03-03 2017-09-07 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves
US10751209B2 (en) 2016-05-19 2020-08-25 Metamodix, Inc. Pyloric anchor retrieval tools and methods
US11666470B2 (en) 2016-05-19 2023-06-06 Metamodix, Inc Pyloric anchor retrieval tools and methods
US10548597B2 (en) 2017-08-14 2020-02-04 Standard Bariatrics, Inc. Surgical stapling devices and methods of using same
US11559305B2 (en) 2017-08-14 2023-01-24 Standard Bariatrics, Inc. Stapling systems and methods for surgical devices and end effectors
US11197672B2 (en) 2017-08-14 2021-12-14 Standard Bariatrics, Inc. Buttress systems and methods for surgical stapling devices and end effectors
US10966721B2 (en) 2017-08-14 2021-04-06 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10912562B2 (en) 2017-08-14 2021-02-09 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US10849623B2 (en) 2017-08-14 2020-12-01 Standard Bariatrics, Inc. Buttress systems and methods for surgical stapling devices and end effectors
US11871927B2 (en) 2017-08-14 2024-01-16 Standard Bariatrics, Inc. End effectors, surgical stapling devices, and methods of using same
US11911033B2 (en) 2017-08-14 2024-02-27 Standard Bariatrics, Inc. Stapling systems and methods for surgical devices and end effectors
US10687814B2 (en) 2017-08-14 2020-06-23 Standard Bariatrics, Inc. Stapling systems and methods for surgical devices and end effectors
US11602449B2 (en) 2019-11-04 2023-03-14 Standard Bariatrics, Inc. Systems and methods of performing surgery using Laplace's law tension retraction during surgery
US11173060B2 (en) 2019-11-04 2021-11-16 Standard Bariatrics, Inc. Systems and methods of performing surgery using Laplace's law tension retraction during surgery
US11452574B1 (en) 2021-03-23 2022-09-27 Standard Bariatrics, Inc. Systems and methods for preventing tissue migration in surgical staplers

Also Published As

Publication number Publication date
WO2005037072A2 (en) 2005-04-28
WO2005037072A3 (en) 2007-05-18
JP2007514462A (en) 2007-06-07
EP1681984A2 (en) 2006-07-26
CN101076289A (en) 2007-11-21
US8430891B2 (en) 2013-04-30
EP1681984A4 (en) 2013-05-29
US20110172685A1 (en) 2011-07-14
US20070260276A1 (en) 2007-11-08

Similar Documents

Publication Publication Date Title
US8430891B2 (en) Transesophageal gastric reduction device, system and method
US20080172074A1 (en) Transesophageal gastric reduction method and device for practicing same
US7220284B2 (en) Gastrointestinal sleeve device and methods for treatment of morbid obesity
US6454785B2 (en) Percutaneous intragastric balloon catheter for the treatment of obesity
US20070191871A1 (en) Transesophageal gastric reduction method and device for reducing the size of a previously formed gastric reduction pouch
US20100217288A1 (en) Transesophageal gastric reduction method and device for practicing same
US6572627B2 (en) System to inhibit and/or control expansion of anatomical features
US6981978B2 (en) Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US8083757B2 (en) Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US8114045B2 (en) Apparatus and methods for delaying gastric emptying to treat obesity
US20080249533A1 (en) Medical Device and Method For Controlling Obesity
US7815629B2 (en) Apparatus for treating obesity by extracting food
US8282623B2 (en) Method for treating obesity by extracting food
US20080051823A1 (en) Devices and methods for treatment of obesity
WO2007018122A1 (en) Balloon to be placed and left in stomach
US20140121582A1 (en) Transesophageal gastric reduction method and device for practicing same
US20140180301A1 (en) Transesophageal gastric reduction method and device for reducing the size of a previously formed gastric reduction pouch

Legal Events

Date Code Title Description
AS Assignment

Owner name: ENDOGASTRIC SOLUTIONS, INC., WASHINGTON

Free format text: CHANGE OF NAME;ASSIGNOR:ENDO GASTRIC SOLUTIONS, INC.;REEL/FRAME:021901/0887

Effective date: 20050830

AS Assignment

Owner name: ENDO GASTRIC SOLUTIONS, INC., WASHINGTON

Free format text: CHANGE OF NAME;ASSIGNOR:ESOPHYX, INC.;REEL/FRAME:022137/0807

Effective date: 20050711

AS Assignment

Owner name: CHICAGO GROWTH PARTNERS, LP, ILLINOIS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: FOUNDATION MEDICAL PARTNERS II, L.P, CONNECTICUT

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII, L.P., MASSACHUSE

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII (B), L.P., MASSAC

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII (C), L.P., MASSAC

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ATV ENTREPRENEURS VII, L.P., MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III, L.P., MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III-QP, L.P., MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG, MA

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III PARALLEL FUND, L.P., MASSACHUS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM ASSET MANAGEMENT INVESTORS 2003 BVIII LLC, MAS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES II, L.P., MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES II-QP, L.P., MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS K

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM ASSET MANAGEMENT INVESTORS 2000 B LLC, MASSACH

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: DE NOVO VENTURES III, LP, CALIFORNIA

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: OAKWOOD MEDICAL INVESTORS IV (QP), L.L.C., MISSOUR

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: OAKWOOD MEDICAL INVESTORS IV, L.L.C., MISSOURI

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: CHICAGO GROWTH PARTNERS, LP,ILLINOIS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: FOUNDATION MEDICAL PARTNERS II, L.P,CONNECTICUT

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII, L.P.,MASSACHUSET

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII (B), L.P.,MASSACH

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ADVANCED TECHNOLOGY VENTURES VII (C), L.P.,MASSACH

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: ATV ENTREPRENEURS VII, L.P.,MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III, L.P.,MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III-QP, L.P.,MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG,MAS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES III PARALLEL FUND, L.P.,MASSACHUSE

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM ASSET MANAGEMENT INVESTORS 2003 BVIII LLC,MASS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES II, L.P.,MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM BIOVENTURES II-QP, L.P.,MASSACHUSETTS

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: MPM ASSET MANAGEMENT INVESTORS 2000 B LLC,MASSACHU

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: DE NOVO VENTURES III, LP,CALIFORNIA

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: OAKWOOD MEDICAL INVESTORS IV (QP), L.L.C.,MISSOURI

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

Owner name: OAKWOOD MEDICAL INVESTORS IV, L.L.C.,MISSOURI

Free format text: SECURITY AGREEMENT;ASSIGNOR:ENDOGASTRIC SOLUTIONS, INC.;REEL/FRAME:022529/0024

Effective date: 20090409

AS Assignment

Owner name: ENDOGASTRIC SOLUTIONS, INC.,WASHINGTON

Free format text: RELEASE BY SECURED PARTY;ASSIGNORS:CHICAGO GROWTH PARTNERS, LP;DE NOVO VENTURES III, LP;MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS KG;AND OTHERS;SIGNING DATES FROM 20100128 TO 20100210;REEL/FRAME:023915/0906

Owner name: ENDOGASTRIC SOLUTIONS, INC., WASHINGTON

Free format text: RELEASE BY SECURED PARTY;ASSIGNORS:CHICAGO GROWTH PARTNERS, LP;DE NOVO VENTURES III, LP;MPM BIOVENTURES GMBH & CO. PARALLEL-BETEILIGUNGS KG;AND OTHERS;SIGNING DATES FROM 20100128 TO 20100210;REEL/FRAME:023915/0906

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION