US20050106075A1 - Fluid system coupler - Google Patents
Fluid system coupler Download PDFInfo
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- US20050106075A1 US20050106075A1 US10/715,574 US71557403A US2005106075A1 US 20050106075 A1 US20050106075 A1 US 20050106075A1 US 71557403 A US71557403 A US 71557403A US 2005106075 A1 US2005106075 A1 US 2005106075A1
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- United States
- Prior art keywords
- coupler
- fluid
- fluid container
- tissue
- cylindrical ring
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
- B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
- B01L3/5635—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors connecting two containers face to face, e.g. comprising a filter
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Definitions
- the present invention is directed to a coupler providing fluid communication between a container and a tubing system, as may be used in instruments requiring reagent or fluid supply.
- Tissue processors can be operated with varying levels of automation to process tissue for histology or pathology, such as from tissue grossing through slide staining.
- Various types of fluids including chemical reagents, can be used at various stages of tissue processing.
- the fluids can be furnished in various ways, such as via small quantity release dispensers, manual dispensing into reagent vats, or via bulk containers connected with a processor via tubing.
- one known system provides a reagent container connected via a tube protruding through a cap. This can suffer disadvantages of leakage in processing and difficulty in properly connecting the tubes.
- the present invention alleviates to a great extent the disadvantages of the known devices for providing fluids such as reagents to processing systems requiring the fluids.
- the preferred example provided is of couplers providing a fluid connection between a fluid container and a tissue processing system, such as may be used in pathology or histology laboratory for processing harvested tissue samples for ultimate examination or testing.
- a coupler is provided that connects to a fluid container and to one or more mating component of the processing system.
- the coupler provides bi-directional fluid communication between at least one fluid container and a receiving tubing system of an instrument.
- the coupler has a structure for connecting with a fluid container, such as internal threads or a pin connector.
- a fluid container such as internal threads or a pin connector.
- the inside of the connector forms a fluid tight seal with the container.
- the coupler also includes a structure for connecting to a mating connector in the tissue processor, and the coupler preferably also provides for bi-directional fluid communication between the fluid container and the tissue processor.
- the structure optionally includes concentric cylinders, which also will be referred to as cylindrical rings, providing at least one egress opening surrounded by a cylindrical ring through which fluid can flow from the container to the tissue processor. Also provided is at least one input opening through which fluid can flow from the tissue container to the tissue processor.
- the input opening or openings preferably are located concentrically outwards from the cylindrical ring around the egress opening.
- a further cylindrical ring is provided concentrically outward from the input opening(s), forming a portion of a ring seal with corresponding structure on the connector in the tissue processor.
- the coupler is used for connecting a reagent container to a tissue processing system.
- the coupler can be used for connecting any suitable fluid container to a fluid using system.
- a mating connector is provided to link with the coupler.
- the mating connector has cylindrical rings that mate with corresponding cylindrical rings on the coupler, forming fluid tight seals, both with the exterior and between the egress and input openings.
- the connector can provide a connection to tubing directing the fluid as desired within the fluid using system from the egress opening of the coupler.
- the fluid using system also preferably includes a locking assembly for attaching the coupler in fluid communication with the connector.
- the locking assembly includes a handle that can be manually engaged to displace the connector to a position in which its cylindrical rings extend within the coupler's rings.
- the locking assembly and coupler are color coordinated to assist an operator to position correct reagent containers in the correct location on the fluid using system.
- the fluid container is used to provide microwave retort reagents to a tissue processing system. Once tissue processing using the reagents has been completed, the reagents may be drained back into the fluid container.
- the fluid container is optionally designed for one time use only.
- FIG. 1 is a perspective view of an assembly in accordance with the principles of the present invention
- FIG. 2 is a perspective view of an assembly in accordance with the principles of the present invention.
- FIG. 3 is a perspective view of an assembly in accordance with the principles of the present invention.
- FIG. 4 is a side view of an assembly in accordance with the principles of the present invention.
- FIG. 5 is a perspective view of a component of an assembly in accordance with the principles of the present invention.
- FIG. 6 is a top view of a component of an assembly in accordance with the principles of the present invention.
- FIG. 7 is a bottom view of a component of an assembly in accordance with the principles of the present invention.
- FIG. 8 is a sectional view of a component of an assembly in accordance with the principles of the present invention.
- FIG. 9 is a perspective view of an assembly in accordance with the principles of the present invention.
- FIG. 10 is a cross-sectional view of the assembly of FIG. 9 taken along line 9 A- 9 A;
- FIG. 11 is a perspective view of an assembly in accordance with the principles of the present invention.
- the fluid container assembly 10 comprises fluid container 20 , coupler 30 , tube 40 and cap 50 .
- Coupler 30 illustrates an example of a coupler in accordance with the present invention that provides fluid communication between the container 20 and a fluid using system, such as for example a tissue processor 55 (see FIG. 9 ).
- Tubing 40 extends from the coupler to the bottom of fluid container 20 .
- Fluid container 20 optionally includes a label 60 .
- the label 60 can display information concerning the contents of the fluid container 20 and instructions for operation and storage.
- the label 60 is, or includes, a machine readable graphic, such as a bar code.
- the machine readable graphic can contain any form of desired identifying or usage information, such as identification of the type of fluid, size of container, storage recommendations, shelf life, expiration date, instrument identifiers and so on.
- the cap 50 is optionally provided to provide a fluid-tight seal over coupler 30 .
- the fluid container assembly 10 optionally includes a tamper resistant seal 70 disposed around cap 50 .
- the tamper resistant seal 70 can be any form of seal such as a plastic or shrink wrap that can inhibit accidental opening of cap 50 .
- fluid container 20 also includes a body 80 , a neck 90 and a handle 100 , although any structure of container 20 can be used that can contain a fluid retained within it.
- fluid container 20 is preferably made from a durable plastic such as high density polyethylene, but alternatively it can be made of other polymeric materials, glass, lined or coated paper or cellulose etc.
- FIG. 3 shows the fluid container assembly 10 after an optional tamper resistant seal 70 and cap 50 have been removed
- FIG. 4 shows the fluid container assembly 10 without coupler 30 and tubing 40
- coupler 30 includes external spiral threads 110 that receive corresponding spiral threads disposed on the interior surface of cap 50
- cap 50 may be attached to coupler 30 by other means such as by force fit or friction fit.
- coupler 30 further includes internal spiral threads 120 for engaging complementary spiral threads 130 (see FIG. 4 ) disposed around the neck of fluid container 20 .
- Coupler 30 may be made from any number of materials including, but not limited to, plastics, glass and other materials.
- one suitable material for coupler 30 is polypropylene.
- Coupler 30 optionally includes a seal 135 that covers a top end 30 a of the coupler during shipping. Seal 135 preferably comprises a thin sheet of aluminum foil having one side covered with adhesive. The seal should be peeled off of the coupler prior to use.
- coupler 30 comprises first and second cylindrical rings 140 , 150 interconnected by a wall 160 including at least one ventilation aperture 160 a .
- first cylindrical ring 140 includes external spiral threads 110 for engaging cap 50 and second cylindrical ring 150 includes internal spiral threads 120 for engaging fluid container 20 .
- Coupler 30 further comprises an inner cylindrical ring 170 that forms a fluid conduit 170 a extending through wall 160 from the first cylindrical ring into the second cylindrical ring. Fluid conduit 170 permits fluids (such as reagents) to be drawn upwardly from tubing 40 and into the tissue processor 55 .
- wall 160 includes six ventilation apertures 160 a concentrically spaced about fluid conduit 170 . As would be understood to those of skill in the art, any number, shape and arrangement of apertures my be used to achieve the desired amount of ventilation without departing from the scope of the present invention.
- Coupler 30 further comprises a retention cylindrical ring 180 for maintaining fluid communication between fluid conduit 170 and tubing 40 . More particularly, as shown in FIG. 8 , retention cylindrical ring 180 extends downwardly from wall 160 around the outer circumference of fluid conduit 170 , thereby forming a cylindrical gap 190 between the fluid conduit and retention cylindrical ring. In FIG. 8 , the dotted lines representing internal spiral threads 120 have been removed for illustrative purposes. As shown in FIG. 8 , tubing 40 is dimensioned to be attached to coupler 30 by way of a force or friction fit within cylindrical gap 190 . Alternatively, the coupler and tubing may be welded together, or otherwise manufactured as a single integral piece.
- a pair of container assemblies 10 are disposed within a cabinet 200 of tissue processor 55 .
- Each fluid container assembly 10 can be connected in fluid communication with the tissue processor using a locking assembly 210 .
- Locking assembly 210 comprises a handle 220 for displacing a fluid connector 230 . More particularly, in order to lock down a fluid container 20 , handle 220 is displaced downward within slots 240 from an unlocked position 250 to a locked position 260 such that fluid connector 230 moves from an unlocked first position above coupler 30 to a locked second position within the top cylindrical ring 140 of coupler 30 . To release the locking assembly, handle 220 is further displaced downward within slots 240 to a release position 270 , thereby causing fluid connector 230 to retract to the unlocked position above coupler 30 .
- the locking assemblies 210 and container assemblies 10 are color coordinated to facilitate proper matching.
- a fluid container assembly 210 may include a yellow coupler 30 adapted to match a locking assembly 210 including a yellow handle 220 .
- a fluid container assembly 210 may include a purple coupler 30 adapted to match a locking assembly 210 including a purple handle 220 .
- other components of the locking and container assemblies e.g., the fluid connector 230 and label area 60
- fluid connector 230 comprises a two-way fluid valve including three concentric rings 280 , 290 , 300 comprising an outer ring 280 , a middle ring 290 and an inner ring 300 forming a central fluid conduit 300 a .
- FIG. 11 shows the fluid connector in the locked position within the top cylindrical ring 140 of coupler 30 .
- Rings 290 , 300 are adapted to slide telescopically within outer ring 280 such that rings 290 , 300 are displaced downward when handle 220 is pulled downward from the unlocked position 250 to the locked position 260 .
- a portion of inner cylindrical ring 170 is disposed within inner ring 300 , thereby providing fluid communication from fluid conduit 170 a to fluid conduit 300 a .
- a portion of middle ring 290 is disposed within the upper cylindrical ring 140 of coupler 30 , thereby providing communication from ventilation conduit 310 to fluid container 20 via ventilation apertures 160 a .
- one or more o-rings may be provided between inner cylindrical ring 170 and inner ring 300 and between middle ring 290 and upper cylindrical ring 140 .
- the initial step involves providing a fluid container assembly including a fluid container having a neck, a coupler attached to the neck and a cap attached to the coupler.
- the next step involves removing an optional seal 70 from fluid container 20 . This step may be accomplished by peeling off the seal or cutting it off(e.g., with a pair of scissors).
- the next step involves removing cap 50 from coupler 30 .
- the cap is removed by twisting in a counterclockwise direction.
- cap 50 is attached by way of force fit and must be pulled off of coupler 30 using a predetermined amount of force.
- the next step involves removing an optional seal 135 from the top end 30 a of coupler 30 . This step may be accomplished by peeling off the seal or cutting it off (e.g., with a pair of scissors).
- the next step involves properly positioning fluid container assembly 20 within the cabinet 200 of tissue processor 55 , as depicted in FIG. 9 .
- This step involves determining the type of fluid within the container and positioning the fluid container assembly adjacent an appropriate locking assembly 210 . If fluid container assembly 20 and locking assembly 210 are color coordinated, then the step involves matching the colors of the container and locking assemblies.
- the next step involves mating the container and locking assemblies, thereby providing fluid communication between container 20 and tissue processor 55 . Referring to FIG. 11 , this step involves displacing a portion of the locking assembly relative to coupler 30 . More particularly, this step involves pulling handle 220 downward such that the inner and middle rings are moved partially within the coupler, thereby providing communication between fluid conduits 170 a , 300 a and between ventilation conduit 310 and ventilation apertures 160 a
- tissue processing can begin.
- fluid is drawn into the tissue processor from container 10 through tubing 40 , fluid conduit 170 a and fluid conduit 300 .
- the fluid is automatically returned to the container through fluid conduit 300 , fluid conduit 170 a and tubing 40 .
- cap 50 is mated with coupler 30 and fluid container assembly 20 is disposed in a conventional manner.
Abstract
Description
- The present invention is directed to a coupler providing fluid communication between a container and a tubing system, as may be used in instruments requiring reagent or fluid supply.
- Tissue processors can be operated with varying levels of automation to process tissue for histology or pathology, such as from tissue grossing through slide staining. Various types of fluids, including chemical reagents, can be used at various stages of tissue processing. The fluids can be furnished in various ways, such as via small quantity release dispensers, manual dispensing into reagent vats, or via bulk containers connected with a processor via tubing.
- There are various disadvantages of these prior systems. For example, manually pouring into (or draining) reagent vats suffers a disadvantage being time consuming and requiring pouring accuracy, decreasing the overall efficiency of the tissue processing system. Another disadvantage is that manual operations can be sloppy, requiring clean up of spills and consequential instrument down time. A further disadvantage is that care is required in selecting the correct reagent, increasing the possibility that reagents may be poured into the incorrect vat, either decreasing test accuracy or decreasing operational efficiency as the mistake is corrected.
- As another example, one known system provides a reagent container connected via a tube protruding through a cap. This can suffer disadvantages of leakage in processing and difficulty in properly connecting the tubes.
- In addition the known systems can engender risks that incorrect fluids are used, leading to inaccuracies or other damage in a processing operation. Various connector arrangements also are known, but may suffer disadvantages or connectability to various instruments other than the desired instruments.
- Accordingly, there exists a need for a structured coupler that provides a fluid connection between one or more fluid containers and a tissue processor.
- The present invention alleviates to a great extent the disadvantages of the known devices for providing fluids such as reagents to processing systems requiring the fluids. The preferred example provided is of couplers providing a fluid connection between a fluid container and a tissue processing system, such as may be used in pathology or histology laboratory for processing harvested tissue samples for ultimate examination or testing. A coupler is provided that connects to a fluid container and to one or more mating component of the processing system. Preferably, the coupler provides bi-directional fluid communication between at least one fluid container and a receiving tubing system of an instrument.
- In one embodiment of the invention, the coupler has a structure for connecting with a fluid container, such as internal threads or a pin connector. Preferably the inside of the connector forms a fluid tight seal with the container. The coupler also includes a structure for connecting to a mating connector in the tissue processor, and the coupler preferably also provides for bi-directional fluid communication between the fluid container and the tissue processor. The structure optionally includes concentric cylinders, which also will be referred to as cylindrical rings, providing at least one egress opening surrounded by a cylindrical ring through which fluid can flow from the container to the tissue processor. Also provided is at least one input opening through which fluid can flow from the tissue container to the tissue processor. The input opening or openings preferably are located concentrically outwards from the cylindrical ring around the egress opening. A further cylindrical ring is provided concentrically outward from the input opening(s), forming a portion of a ring seal with corresponding structure on the connector in the tissue processor.
- In one embodiment, the coupler is used for connecting a reagent container to a tissue processing system. However, it should be understood that the coupler can be used for connecting any suitable fluid container to a fluid using system. In the fluid using system, a mating connector is provided to link with the coupler. Preferably, the mating connector has cylindrical rings that mate with corresponding cylindrical rings on the coupler, forming fluid tight seals, both with the exterior and between the egress and input openings. In addition, the connector can provide a connection to tubing directing the fluid as desired within the fluid using system from the egress opening of the coupler. The fluid using system also preferably includes a locking assembly for attaching the coupler in fluid communication with the connector. In one embodiment, the locking assembly includes a handle that can be manually engaged to displace the connector to a position in which its cylindrical rings extend within the coupler's rings. Optionally, the locking assembly and coupler are color coordinated to assist an operator to position correct reagent containers in the correct location on the fluid using system.
- In one application, the fluid container is used to provide microwave retort reagents to a tissue processing system. Once tissue processing using the reagents has been completed, the reagents may be drained back into the fluid container. The fluid container is optionally designed for one time use only.
- These and other features and advantages of the present invention will be appreciated from review of the following detailed description of the invention, along with the accompanying figures in which like reference numerals refer to like parts throughout.
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FIG. 1 is a perspective view of an assembly in accordance with the principles of the present invention; -
FIG. 2 is a perspective view of an assembly in accordance with the principles of the present invention; -
FIG. 3 is a perspective view of an assembly in accordance with the principles of the present invention; -
FIG. 4 is a side view of an assembly in accordance with the principles of the present invention; -
FIG. 5 is a perspective view of a component of an assembly in accordance with the principles of the present invention; -
FIG. 6 is a top view of a component of an assembly in accordance with the principles of the present invention; -
FIG. 7 is a bottom view of a component of an assembly in accordance with the principles of the present invention; -
FIG. 8 is a sectional view of a component of an assembly in accordance with the principles of the present invention; -
FIG. 9 is a perspective view of an assembly in accordance with the principles of the present invention; -
FIG. 10 is a cross-sectional view of the assembly ofFIG. 9 taken alongline 9A-9A; and -
FIG. 11 is a perspective view of an assembly in accordance with the principles of the present invention. - In the following paragraphs, the present invention will be described in detail by way of example with reference to the figures. Throughout this description, the preferred embodiment and examples shown should be considered as exemplars, rather than as limitations on the present invention. As used herein, the “present invention” refers to any one of the embodiments of the invention described herein, and any equivalents. Furthermore, reference to various feature(s) of the “present invention” throughout this document does not mean that all claimed embodiments or methods must include the referenced feature(s).
- Referring to
FIGS. 1 and 2 , an embodiment of afluid container assembly 10 according to present invention will be described. Generally speaking, thefluid container assembly 10 comprisesfluid container 20,coupler 30,tube 40 andcap 50.Coupler 30 illustrates an example of a coupler in accordance with the present invention that provides fluid communication between thecontainer 20 and a fluid using system, such as for example a tissue processor 55 (seeFIG. 9 ).Tubing 40 extends from the coupler to the bottom offluid container 20. -
Fluid container 20 optionally includes alabel 60. Thelabel 60 can display information concerning the contents of thefluid container 20 and instructions for operation and storage. In one embodiment, thelabel 60 is, or includes, a machine readable graphic, such as a bar code. The machine readable graphic can contain any form of desired identifying or usage information, such as identification of the type of fluid, size of container, storage recommendations, shelf life, expiration date, instrument identifiers and so on. - The
cap 50 is optionally provided to provide a fluid-tight seal overcoupler 30. However, other forms of fluid-tight seals, such as foil or coated paper also may be used. Thefluid container assembly 10 optionally includes a tamperresistant seal 70 disposed aroundcap 50. The tamperresistant seal 70 can be any form of seal such as a plastic or shrink wrap that can inhibit accidental opening ofcap 50. In the illustrated embodiment,fluid container 20 also includes abody 80, aneck 90 and ahandle 100, although any structure ofcontainer 20 can be used that can contain a fluid retained within it. In a preferred embodiment,fluid container 20 is preferably made from a durable plastic such as high density polyethylene, but alternatively it can be made of other polymeric materials, glass, lined or coated paper or cellulose etc. -
FIG. 3 shows thefluid container assembly 10 after an optional tamperresistant seal 70 andcap 50 have been removed, andFIG. 4 shows thefluid container assembly 10 withoutcoupler 30 andtubing 40. In the illustrated embodiment,coupler 30 includes externalspiral threads 110 that receive corresponding spiral threads disposed on the interior surface ofcap 50. Alternatively, cap 50 may be attached tocoupler 30 by other means such as by force fit or friction fit. - Referring to
FIG. 5 ,coupler 30 further includes internalspiral threads 120 for engaging complementary spiral threads 130 (seeFIG. 4 ) disposed around the neck offluid container 20.Coupler 30 may be made from any number of materials including, but not limited to, plastics, glass and other materials. By way of example, one suitable material forcoupler 30 is polypropylene.Coupler 30 optionally includes aseal 135 that covers atop end 30 a of the coupler during shipping.Seal 135 preferably comprises a thin sheet of aluminum foil having one side covered with adhesive. The seal should be peeled off of the coupler prior to use. - Referring to
FIGS. 5-8 ,coupler 30 comprises first and second cylindrical rings 140, 150 interconnected by awall 160 including at least oneventilation aperture 160 a. As best seen inFIG. 5 , firstcylindrical ring 140 includes externalspiral threads 110 for engagingcap 50 and secondcylindrical ring 150 includes internalspiral threads 120 for engagingfluid container 20.Coupler 30 further comprises an innercylindrical ring 170 that forms afluid conduit 170 a extending throughwall 160 from the first cylindrical ring into the second cylindrical ring.Fluid conduit 170 permits fluids (such as reagents) to be drawn upwardly fromtubing 40 and into the tissue processor 55. In the illustrated embodiment,wall 160 includes sixventilation apertures 160 a concentrically spaced aboutfluid conduit 170. As would be understood to those of skill in the art, any number, shape and arrangement of apertures my be used to achieve the desired amount of ventilation without departing from the scope of the present invention. -
Coupler 30 further comprises a retentioncylindrical ring 180 for maintaining fluid communication betweenfluid conduit 170 andtubing 40. More particularly, as shown inFIG. 8 , retentioncylindrical ring 180 extends downwardly fromwall 160 around the outer circumference offluid conduit 170, thereby forming acylindrical gap 190 between the fluid conduit and retention cylindrical ring. InFIG. 8 , the dotted lines representing internalspiral threads 120 have been removed for illustrative purposes. As shown inFIG. 8 ,tubing 40 is dimensioned to be attached tocoupler 30 by way of a force or friction fit withincylindrical gap 190. Alternatively, the coupler and tubing may be welded together, or otherwise manufactured as a single integral piece. - Referring to
FIG. 9 , a pair ofcontainer assemblies 10 are disposed within acabinet 200 of tissue processor 55. Eachfluid container assembly 10 can be connected in fluid communication with the tissue processor using a lockingassembly 210. Lockingassembly 210 comprises ahandle 220 for displacing afluid connector 230. More particularly, in order to lock down afluid container 20, handle 220 is displaced downward withinslots 240 from anunlocked position 250 to a lockedposition 260 such thatfluid connector 230 moves from an unlocked first position abovecoupler 30 to a locked second position within the topcylindrical ring 140 ofcoupler 30. To release the locking assembly, handle 220 is further displaced downward withinslots 240 to arelease position 270, thereby causingfluid connector 230 to retract to the unlocked position abovecoupler 30. - According to some embodiments, the locking
assemblies 210 andcontainer assemblies 10 are color coordinated to facilitate proper matching. As an example, afluid container assembly 210 may include ayellow coupler 30 adapted to match a lockingassembly 210 including ayellow handle 220. Likewise, afluid container assembly 210 may include apurple coupler 30 adapted to match a lockingassembly 210 including apurple handle 220. Alternatively, other components of the locking and container assemblies (e.g., thefluid connector 230 and label area 60) may be color coordinated to facilitate proper fluid container positioning. - Referring to
FIGS. 10 and 11 ,fluid connector 230 comprises a two-way fluid valve including threeconcentric rings outer ring 280, amiddle ring 290 and aninner ring 300 forming a centralfluid conduit 300 a. In addition, there exists a cylindrical space betweenmiddle ring 290 andinner ring 280, which forms aventilation conduit 310.FIG. 11 shows the fluid connector in the locked position within the topcylindrical ring 140 ofcoupler 30.Rings outer ring 280 such that rings 290, 300 are displaced downward whenhandle 220 is pulled downward from theunlocked position 250 to the lockedposition 260. In the locked position, a portion of innercylindrical ring 170 is disposed withininner ring 300, thereby providing fluid communication fromfluid conduit 170 a tofluid conduit 300 a. Additionally, a portion ofmiddle ring 290 is disposed within the uppercylindrical ring 140 ofcoupler 30, thereby providing communication fromventilation conduit 310 tofluid container 20 viaventilation apertures 160 a. To ensure fluid tight connections, one or more o-rings may be provided between innercylindrical ring 170 andinner ring 300 and betweenmiddle ring 290 and uppercylindrical ring 140. - Referring to
FIG. 12 , a method of coupling afluid container assembly 10 with a tissue processor 55 having one or more fluidcontainer locking assemblies 210 will now be described. As illustrated diagrammatically asbox 320, the initial step involves providing a fluid container assembly including a fluid container having a neck, a coupler attached to the neck and a cap attached to the coupler. As illustrated diagrammatically asbox 330, the next step involves removing anoptional seal 70 fromfluid container 20. This step may be accomplished by peeling off the seal or cutting it off(e.g., with a pair of scissors). - As illustrated diagrammatically as
box 340, the next step involves removingcap 50 fromcoupler 30. According to some embodiments, the cap is removed by twisting in a counterclockwise direction. According to other embodiments,cap 50 is attached by way of force fit and must be pulled off ofcoupler 30 using a predetermined amount of force. As illustrated diagrammatically asbox 350, the next step involves removing anoptional seal 135 from thetop end 30 a ofcoupler 30. This step may be accomplished by peeling off the seal or cutting it off (e.g., with a pair of scissors). - As illustrated diagrammatically as
box 360, the next step involves properly positioningfluid container assembly 20 within thecabinet 200 of tissue processor 55, as depicted inFIG. 9 . This step involves determining the type of fluid within the container and positioning the fluid container assembly adjacent anappropriate locking assembly 210. Iffluid container assembly 20 and lockingassembly 210 are color coordinated, then the step involves matching the colors of the container and locking assemblies. As illustrated diagrammatically asbox 370, the next step involves mating the container and locking assemblies, thereby providing fluid communication betweencontainer 20 and tissue processor 55. Referring toFIG. 11 , this step involves displacing a portion of the locking assembly relative tocoupler 30. More particularly, this step involves pullinghandle 220 downward such that the inner and middle rings are moved partially within the coupler, thereby providing communication betweenfluid conduits ventilation conduit 310 andventilation apertures 160 a - After proper attachment has been made between
fluid container assembly 20 and machine 55, tissue processing can begin. In operation, fluid is drawn into the tissue processor fromcontainer 10 throughtubing 40,fluid conduit 170 a andfluid conduit 300. After tissue processing using the fluid has been completed, the fluid is automatically returned to the container throughfluid conduit 300,fluid conduit 170 a andtubing 40. After fluid return,cap 50 is mated withcoupler 30 andfluid container assembly 20 is disposed in a conventional manner. - Thus, it is seen that a coupler providing bi-directional fluid communication between a fluid container and a tissue processor is provided. One skilled in the art will appreciate that the present invention can be practiced by other than the various embodiments and preferred embodiments, which are presented in this description for purposes of illustration and not of limitation, and the present invention is limited only by the claims that follow. It is noted that equivalents for the particular embodiments discussed in this description may practice the invention as well.
Claims (32)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/715,574 US7431890B2 (en) | 2003-11-17 | 2003-11-17 | Fluid system coupler |
PCT/US2004/037071 WO2005050162A2 (en) | 2003-11-17 | 2004-11-05 | Fluid system coupler |
CA002546380A CA2546380C (en) | 2003-11-17 | 2004-11-05 | Fluid system coupler |
AU2004291848A AU2004291848B2 (en) | 2003-11-17 | 2004-11-05 | Fluid system coupler |
ES04800835.3T ES2535431T3 (en) | 2003-11-17 | 2004-11-05 | Fluid System Coupler |
DK04800835.3T DK1684905T3 (en) | 2003-11-17 | 2004-11-05 | FLUID SYSTEM COUPLING DEVICE |
CN200480038202.XA CN101027132B (en) | 2003-11-17 | 2004-11-05 | Fluid system coupler |
BRPI0416671-0A BRPI0416671B1 (en) | 2003-11-17 | 2004-11-05 | Coupler connecting a fluid container and a tissue processing apparatus and method of coupling a fluid container with a tissue processor. |
EP04800835.3A EP1684905B1 (en) | 2003-11-17 | 2004-11-05 | Fluid system coupler |
JP2006541228A JP4262751B2 (en) | 2003-11-17 | 2004-11-05 | Fluid system coupling |
US12/203,841 US7837945B2 (en) | 2003-11-17 | 2008-09-03 | Fluid system coupler |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/715,574 US7431890B2 (en) | 2003-11-17 | 2003-11-17 | Fluid system coupler |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/203,841 Division US7837945B2 (en) | 2003-11-17 | 2008-09-03 | Fluid system coupler |
Publications (2)
Publication Number | Publication Date |
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US20050106075A1 true US20050106075A1 (en) | 2005-05-19 |
US7431890B2 US7431890B2 (en) | 2008-10-07 |
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Application Number | Title | Priority Date | Filing Date |
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US10/715,574 Expired - Lifetime US7431890B2 (en) | 2003-11-17 | 2003-11-17 | Fluid system coupler |
US12/203,841 Expired - Lifetime US7837945B2 (en) | 2003-11-17 | 2008-09-03 | Fluid system coupler |
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US12/203,841 Expired - Lifetime US7837945B2 (en) | 2003-11-17 | 2008-09-03 | Fluid system coupler |
Country Status (10)
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US (2) | US7431890B2 (en) |
EP (1) | EP1684905B1 (en) |
JP (1) | JP4262751B2 (en) |
CN (1) | CN101027132B (en) |
AU (1) | AU2004291848B2 (en) |
BR (1) | BRPI0416671B1 (en) |
CA (1) | CA2546380C (en) |
DK (1) | DK1684905T3 (en) |
ES (1) | ES2535431T3 (en) |
WO (1) | WO2005050162A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2786802A1 (en) * | 2013-04-03 | 2014-10-08 | Metrohm Ag | Lock for a container |
CN108313442A (en) * | 2018-04-11 | 2018-07-24 | 丹江口娇阳包装技术有限公司 | Bottle |
EP3711857A1 (en) * | 2019-03-18 | 2020-09-23 | Avantor Fluid Handling, LLC | Adjustable volume sampling system (avss) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9700827B2 (en) * | 2012-05-11 | 2017-07-11 | Thomas & Betts International Llc | Drain adaptor |
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- 2004-11-05 CN CN200480038202.XA patent/CN101027132B/en active Active
- 2004-11-05 JP JP2006541228A patent/JP4262751B2/en active Active
- 2004-11-05 EP EP04800835.3A patent/EP1684905B1/en active Active
- 2004-11-05 CA CA002546380A patent/CA2546380C/en active Active
- 2004-11-05 WO PCT/US2004/037071 patent/WO2005050162A2/en active Search and Examination
- 2004-11-05 DK DK04800835.3T patent/DK1684905T3/en active
- 2004-11-05 ES ES04800835.3T patent/ES2535431T3/en active Active
- 2004-11-05 AU AU2004291848A patent/AU2004291848B2/en active Active
- 2004-11-05 BR BRPI0416671-0A patent/BRPI0416671B1/en active IP Right Grant
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2008
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US4806316A (en) * | 1987-03-17 | 1989-02-21 | Becton, Dickinson And Company | Disposable device for use in chemical, immunochemical and microorganism analysis |
US4854486A (en) * | 1987-05-11 | 1989-08-08 | Ciba Corning Diagnostics Corp. | Resealable container for dispensing liquid |
US5366902A (en) * | 1990-10-30 | 1994-11-22 | Hypoguard (Uk) Limited | Collection and display device |
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Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2692035C2 (en) * | 2013-04-03 | 2019-06-19 | Метром Аг | Container cover |
WO2014161831A3 (en) * | 2013-04-03 | 2014-11-27 | Metrohm Ag | Closure for a container |
CN105263629A (en) * | 2013-04-03 | 2016-01-20 | 瑞士万通集团公司 | Closure for a container |
EP2981356A2 (en) * | 2013-04-03 | 2016-02-10 | Metrohm Ag | Closure for a container |
US20160052683A1 (en) * | 2013-04-03 | 2016-02-25 | Metrohm Ag | Closure for a container |
EP2786802A1 (en) * | 2013-04-03 | 2014-10-08 | Metrohm Ag | Lock for a container |
US10737855B2 (en) * | 2013-04-03 | 2020-08-11 | Metrohm Ag | Closure for a container |
US20200339322A1 (en) * | 2013-04-03 | 2020-10-29 | Metrohm Ag | Closure for a container |
EP2981356B1 (en) * | 2013-04-03 | 2021-09-01 | Metrohm Ag | Closure for a container |
EP3928866A1 (en) * | 2013-04-03 | 2021-12-29 | Metrohm AG | Lock for a container |
CN108313442A (en) * | 2018-04-11 | 2018-07-24 | 丹江口娇阳包装技术有限公司 | Bottle |
EP3711857A1 (en) * | 2019-03-18 | 2020-09-23 | Avantor Fluid Handling, LLC | Adjustable volume sampling system (avss) |
US11320345B2 (en) | 2019-03-18 | 2022-05-03 | Avantor Fluid Handling, Llc | Adjustable volume sampling system (AVSS) |
Also Published As
Publication number | Publication date |
---|---|
BRPI0416671A (en) | 2007-02-13 |
EP1684905B1 (en) | 2015-04-01 |
JP2007511436A (en) | 2007-05-10 |
CN101027132A (en) | 2007-08-29 |
US20090004065A1 (en) | 2009-01-01 |
JP4262751B2 (en) | 2009-05-13 |
AU2004291848A1 (en) | 2005-06-02 |
CA2546380A1 (en) | 2005-06-02 |
ES2535431T3 (en) | 2015-05-11 |
AU2004291848B2 (en) | 2007-12-13 |
EP1684905A4 (en) | 2012-10-10 |
DK1684905T3 (en) | 2015-05-04 |
WO2005050162A3 (en) | 2005-11-24 |
BRPI0416671B1 (en) | 2015-07-28 |
CA2546380C (en) | 2010-01-05 |
EP1684905A2 (en) | 2006-08-02 |
US7431890B2 (en) | 2008-10-07 |
WO2005050162A2 (en) | 2005-06-02 |
CN101027132B (en) | 2010-11-17 |
US7837945B2 (en) | 2010-11-23 |
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