US20060004410A1 - Suture locking and cutting devices and methods - Google Patents
Suture locking and cutting devices and methods Download PDFInfo
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- US20060004410A1 US20060004410A1 US11/127,955 US12795505A US2006004410A1 US 20060004410 A1 US20060004410 A1 US 20060004410A1 US 12795505 A US12795505 A US 12795505A US 2006004410 A1 US2006004410 A1 US 2006004410A1
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Definitions
- This invention relates to endoscopic suturing devices and methods, including devices and methods which may pass through or be employed in connection with the working channel of various endoscopic and ultrasound devices.
- sutures in the gastrointestinal tract is required for several different types of medical procedures, for example, for transoral endoscopic valvuloplasty for gastroesophageal reflux disease (GERD), gastroplasty, fundoplication, anterior gastropexy, posterior gastropexy, suturing esophageal perforations, or closure of the esophageal side of the tracheo-esophageal fistula.
- gastroesophageal reflux disease GUD
- gastroplasty gastroplasty
- fundoplication anterior gastropexy
- posterior gastropexy posterior gastropexy
- suturing esophageal perforations or closure of the esophageal side of the tracheo-esophageal fistula.
- closure of the esophageal side of the tracheo-esophageal fistula closure of the esophageal side of the tracheo-esophageal fistula.
- these procedures are performed by physicians, such as gastro
- Such procedures are invasive, as laparoscopy requires that small access incision(s) be made in the body of the patient, through which a laparoscope and other surgical enabling tools are provided, while open surgical techniques are traditionally invasive and can have complications and cause long patient recovery periods.
- EUS endoscopic ultrasound
- the median arcuate ligament and part of the right crus were identified and punctured with a needle, which served as a carrier for a tag and suture. These were anchored into the muscle.
- An endoscopic sewing device was used, which allowed stitches to be placed through a 2.8-mm accessory channel to any predetermined depth.
- the publication also describes new methods of knot tying and suture cutting through the 2.8-mm channel of the EUS. More specifically, stitches were placed through the gastric wall into the median arcuate ligament, and one stitch was placed just beyond the wall of the lower esophageal sphincter. The stitches were tied together and locked against the gastric wall, and the surplus length of suture material was then cut and removed. While this publication describes a suitable transgastric gastropexy and hiatal hernia repair procedure, further improvements in methodology and equipment to perform such procedures would be beneficial. For example, the publication describes a process for locking and cutting the suture from inside the stomach. However, the suture requires that a separate suture cutting step, along with its associated cutting instrumentation, be available via the working channel of the endoscope. This may result in multiple passes of instrumentation back and forth through the working channel of the endoscope. What is needed is a way to both lock and cut a suture automatically with a single device and thereby simplify the medical procedure, such as a posterior gastropexy procedure
- the locking mechanism described in the publication is too large to pass through the working channel of an endoscope and, thus, it must be inserted into the patient separately from the endoscope, which again adds complexity to the medical procedure. What is needed are suture locking and cutting mechanisms that are small enough to pass through the working channel of various endoscopic and ultrasound devices (typical working channel diameter is 2.8-3.4 mm).
- Certain embodiments of the present invention are directed to providing improved methods of performing a totally transoral surgical procedure, such as a posterior gastropexy procedure, and thereby avoiding more-invasive laparoscopic procedures.
- One embodiment of the present invention provides a device and method that allows a physician in a medical procedure to automatically lock and cut a suture in one motion and without the need for additional cutting instrumentation, rather than perform separate locking and cutting actions.
- a suture lock assembly in combination with a lock actuating device comprises an extension spring arranged between two endcaps, wherein one or more sutures are locked within the coils thereof. Extending the extension spring allows for one or more sutures to be threaded therethrough and, by relaxing the extension spring, provides a clamping action upon the sutures and a torturous path within the coils.
- the lock actuating device provides a cutting mechanism. Furthermore, both the suture lock assembly, in combination with a lock actuating device, are suitably small enough to pass through the working channel of various endoscopic and ultrasound devices.
- a suture lock assembly in another embodiment, forms a hollow body, within which a clamp device is engaged and through which one or more sutures is threaded. Depending upon the slidable position of the clamp device within the body, the suture within the clamp device is engaged to clamp the suture permanently.
- the suture lock assembly of this embodiment is likewise suitably small enough to pass through the working channel of various endoscopic and ultrasound devices.
- the various embodiments of the invention can be employed with various types of suture, including without limitation monofilament suture and braided suture.
- FIG. 1A illustrates a perspective view of a suture lock assembly in accordance with a first embodiment of the invention
- FIG. 1B illustrates a cross-sectional view of the suture lock assembly in accordance with a first embodiment of the invention
- FIG. 2 illustrates a side view of an exemplary lock actuating device according to the first embodiment
- FIGS. 3A and 3B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the default state;
- FIGS. 4A and 4B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the lock state;
- FIGS. 5A and 5B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the cut state;
- FIG. 6 illustrates a side view of the suture lock assembly of the first embodiment engaged therein in the release state
- FIG. 7 illustrates a flow diagram of an example method of using the suture lock assembly of the first embodiment in combination with the lock actuating system
- FIG. 8 illustrates a perspective view of a suture lock assembly in accordance with a second embodiment of the invention.
- FIG. 9 illustrates a cross-sectional view of the suture lock assembly of the second embodiment in the unlocked state.
- FIG. 10 illustrates a cross-sectional view of the suture lock assembly of the second embodiment in the locked state.
- FIGS. 11A and 11B illustrate cross section views of an alternative locking device with a one-way flap inside a tubular segment, in a loading state, and a locked state, respectively.
- FIGS. 12A and 12B show a cross section view of alternative one-piece clip in a default state, and a cross section view of the one-piece clip in a locked state, respectively.
- FIG. 1A illustrates a perspective view of a suture lock assembly 100 in accordance with a first embodiment of the invention.
- Suture lock assembly 100 includes an extension spring 112 arranged between a distal endcap 114 and a proximal endcap 116 .
- Extension spring 112 is formed of any nontoxic, noncorrosive metal, such as stainless steel, and distal endcap 114 and proximal endcap 116 are formed of, for example, molded plastic or stainless steel. Also shown in FIG. 1 is a suture 118 threaded first through a hole 120 in distal endcap 114 and then through multiple coils of extension spring 112 , wherein suture 118 is clamped because of the pressure of the coils and the tortuous path within the coils.
- Suture lock assembly 100 is not limited to a single suture 118 installed therein; a plurality of sutures 118 may be engaged within a single suture lock assembly 100 .
- FIG. 1B illustrates a cross-sectional view of suture lock assembly 100 taken along line AA of FIG. 1A .
- proximal endcap 116 further includes a hollow channel 121 that runs through its center.
- hole 120 in distal endcap 114 is angled from the center of an outer end of distal endcap 114 toward the sidewall of distal endcap 114 , which thereby allows suture 118 to exit distal endcap 114 external to extension spring 112 .
- Distal endcap 114 and proximal endcap 116 may be insert-molded onto extension spring 112 or use other methods or procedures of providing a smooth, trauma free extension of spring coils.
- suture 118 is threaded first through hole 120 in distal endcap 114 ; extension spring 112 is then extended and suture 118 is threaded through multiple coils of extension spring 112 ; extension spring 112 is then relaxed, which thereby applies a tortuous path in addition to a clamping or locking action upon suture 118 between the coils thereof.
- the overall diameter of suture lock assembly 100 is suitably small enough to allow it to pass through the working channel of various endoscopic and ultrasound devices, which is typically between 2.8 and 3.4 mm in diameter. See Table 1 for example dimensions of suture lock assembly 100 .
- Example dimensions of suture lock assembly 100 Example Dimension Suture lock assembly 100 overall length 0.70 in Extension spring 112 outside diameter 0.060 in Extension spring 112 inside diameter 0.040 in Distal endcap 114 outside diameter 0.07 in Distal endcap 114 length 0.15 in Proximal endcap 116 outside diameter 0.07 in Proximal endcap 116 length 0.125 in Hollow channel 121 diameter 0.04 in Hole 120 diameter 0.04 in Hole 120 angle 45 degrees
- FIG. 2 illustrates a side view of a lock actuating device 200 , which is exemplary only and representative of any suitable actuating device for use with suture lock assembly 100 .
- lock actuating device 200 includes a body 210 that has a knob 212 arranged at its proximal end for grasping by the user.
- Mechanically coupled to body 210 is a retract handle 214 , which has a retract handle body 216 and a retention handle 218 that is slidably arranged within retract handle body 216 .
- a compression spring 220 is mechanically coupled between a spring retainer 222 , which is coupled to knob 212 , and the proximal end of retract handle body 216 .
- FIG. 2 also shows that arranged within the distal end of retractable sleeve 224 is a first slot 230 that is aligned opposite a second slot 232 . Also, arranged within the distal end of retention sleeve 225 is a hole 234 that is aligned opposite a slot 236 .
- Actuating shaft 228 of a fixed length is mechanically coupled at one end to the distal end of spring retainer 222 while passing through spring retainer 222 .
- Actuating shaft 228 passes through a hollow channel within retract handle body 216 , then passes through the hollow channel of retention jaw 226 within retractable sleeve 224 .
- the tip of actuating shaft 228 extends through an opening at the distal end of retention jaw 226 within retractable sleeve 224 .
- retractable sleeve 224 and retention sleeve 225 are slidable along the length of actuating shaft 228 .
- Lock actuating device 200 may include well-known mechanical methods and elements (not shown) for holding retractable sleeve 224 and retention jaw 226 at various positional states.
- suture lock assembly 100 in combination with lock actuating device 200 for automatically locking and cutting a suture includes a sequential transition from a default state (i.e., undeployed state) to a lock state, a cut state and, finally, a release state (i.e., deployed state), as described in reference to FIGS. 3A, 3B , 4 A, 4 B, 5 A, 5 B, 6 , and 7 .
- FIGS. 3A, 3B , 4 A, 4 B, 5 A, 5 B, and 6 show suture lock assembly 100 in use and, therefore, it includes suture 118 , which runs through the center of suture lock assembly 100 and approximates a first tissue 122 and a second tissue 124 .
- Suture 118 is anchored to second tissue 124 with a T-tag 126 , which is a well-known medical device for anchoring a suture into body tissue.
- FIGS. 3A and 3B illustrate a side view and a top view, respectively, of the distal end of lock actuating device 200 with suture lock assembly 100 engaged therein in the default state, which is described as follows.
- extension spring 112 is extended suitably to allow suture 118 to slide freely through its coils. This is accomplished by the physician's passing actuating shaft 228 through hollow channel 121 of proximal endcap 116 , then through the center of extension spring 112 , until the tip of actuating shaft 228 abuts the inner surface of distal endcap 114 .
- retention handle 218 which is attached to the proximal end of retention sleeve 225 , the physician extends retention jaw 226 to allow it to grip proximal endcap 116 and then pull proximal endcap 116 into the tip of retractable sleeve 224 , as shown in FIGS.
- extension spring 112 is threaded first through hole 120 in distal endcap 114 , then within the extended coils of extension spring 112 is wrapped multiple times around actuating shaft 228 , through first slot 230 of retractable sleeve 224 , through hole 234 of retention sleeve 225 , passes around actuating shaft 228 , through slot 236 of retention sleeve 225 and, finally, through second slot 232 of retractable sleeve 224 .
- FIGS. 4A and 4B illustrate a side view and a top view, respectively, of the distal end of lock actuating device 200 with suture lock assembly 100 engaged therein in the lock state, which is described as follows.
- Lock state In the lock state, extension spring 112 is relaxed, which allows its coils to clamp against suture 118 and thereby prevent suture 118 from sliding freely between the coils of extension spring 112 .
- retention handle 218 which is attached to the proximal end of retention sleeve 225 , the physician extends retention jaw 226 while gripping proximal endcap 116 in a direction toward distal endcap 114 and while maintaining the relative distance between the tip of actuating shaft 228 and the tip of retractable sleeve 224 , as set in the default state.
- suture 118 is intact and passing freely through first slot 230 of retractable sleeve 224 , through hole 234 of retention sleeve 225 , passes around actuating shaft 228 , through slot 236 of retention sleeve 225 , and through second slot 232 of retractable sleeve 224 , as shown in FIGS. 4A and 4B .
- FIGS. 5A and 5B illustrate a side view and a top view, respectively, of the distal end of lock actuating device 200 with suture lock assembly 100 engaged therein in the cut state, which is described as follows.
- Cut state In the cut state, the relative distance between the tip of actuating shaft 228 and the tip of retention jaw 226 is maintained, as set in the lock state.
- retract handle 214 which is attached to the proximal end of retractable sleeve 224 , the physician retracts tip of retractable sleeve 224 in a direction away from the tip of retention jaw 226 , which causes the position of hole 234 and slot 236 within retention sleeve 225 to change, relative to first slot 230 and second slot 232 , respectively, such that suture 118 within hole 234 is cut as hole 234 passes underneath the edge of first slot 230 , which has a ground edge suitable for cutting suture 118 .
- FIG. 6 illustrates a side view of suture lock assembly 100 in the release state, which is described as follows.
- Release state In the release state, the physician manipulates the grasp of retention jaw 226 and proximal endcap 116 is released, which allows all instrumentation, such as lock actuating device 200 and the endoscope, as well as the surplus length of suture 118 , to be removed. Extension spring 112 remains relaxed and, thus, the locking action upon suture 118 is maintained indefinitely within the patient.
- the suture 118 can be manually threaded through or otherwise positioned between the extended coils, such as in a serpentine fashion, so that the coils hold the suture when the coils are permitted to close together.
- Such manual positioning of the suture through the coils may be employed if the shaft 228 is not employed or is otherwise not positioned within the spring 112 when the suture is positioned with respect to the coils of spring 112 .
- FIG. 7 illustrates a flow diagram of an example method 700 of using suture lock assembly 100 in combination with lock actuating device 200 in accordance with the invention. More specifically, method 700 provides an example of a posterior gastropexy procedure that uses suture lock assembly 100 of the present invention.
- the use of suture lock assembly 100 is not limited to a posterior gastropexy procedure; suture lock assembly 100 may be used in any of various, similar medical procedures.
- method 700 is not limited to a single suture 118 installed within suture lock assembly 100 ; a plurality of sutures 118 may be engaged within a single suture lock assembly 100 .
- a physician passes an EUS endoscope through a patient's mouth and esophagus and into the stomach.
- Example EUS endoscopes include endoscope model GF-UC160P-AT8 manufactured by Olympus Europe (Hamburg, Germany) and endoscope model EG-3630U manufactured by Pentax Medical Company (Orangeburg, N.Y.).
- the working channel of the EUS endoscope is preloaded with a standard EUS needle, such as is manufactured by Wilson-Cook (Winston-Salem, N.C.), that serves as a carrier for a tag and suture, such as T-tag 126 and suture 118 .
- Suture 118 may run either through the needle or outside the needle, but still inside the working channel of the EUS endoscope.
- the physician locates and identifies structures outside the stomach wall and selects a fixation point, such as the median arcuate ligament.
- the physician pushes the EUS needle, which is carrying T-tag 126 and suture 118 , through the stomach wall, which is represented by first tissue 122 in FIGS. 3A, 3B , 4 A, 4 B, 5 A, 5 B, and 6 .
- the physician deploys and affixes T-tag 126 , with suture 118 attached thereto, to the fixation point, such as to the median arcuate ligament, which is represented by second tissue 124 in FIGS. 3A, 3B , 4 A, 4 B, 5 A, 5 B, and 6 .
- the physician withdraws the EUS endoscope and associated instrumentation from the patient, but leaves a length of suture 118 still threaded through the patient's gastroesophageal tract and anchored to second tissue 124 (e.g., median arcuate ligament).
- the length of suture 118 extends out of the patient's mouth and is accessible to the physician.
- the physician threads the length of suture 118 that is extending out of the patient's mouth into the distal end and out of the proximal end of the working channel of a standard endoscope that has a standard vision system (i.e., not an EUS endoscope).
- the physician passes the endoscope through the patient's mouth and esophagus and into the stomach.
- a length of suture 118 is left extending out of the proximal end of the working channel of the endoscope and is accessible to the physician.
- the physician loads suture lock assembly 100 into the distal end of lock actuating device 200 and sets suture lock assembly 100 into the default state, as described in reference to FIGS. 3A and 3B .
- the physician first threads the length of suture 118 that is extending out of the proximal end of the endoscope through hole 120 in distal endcap 114 , then within the extended coils of extension spring 112 is wrapped multiple times around actuating shaft 228 , then threaded through hole 234 of retention sleeve 225 , then threaded through first slot 230 of retractable sleeve 224 , then threaded through second slot 236 of retention sleeve 225 and, finally, threaded through second slot 232 of retractable sleeve 224 , as shown in FIGS. 3A and 3B .
- step 728 while holding tension on suture 118 , which is extending out of second slot 232 of retractable sleeve 224 , the physician passes the suture lock assembly 100 and retractable sleeve 224 of lock actuating device 200 through the working channel of the endoscope and into the patient's stomach.
- Suture lock assembly 100 is sliding freely along suture 118 in the default state, until distal endcap 114 is firmly abutted against the inside of the stomach wall, which is represented by first tissue 122 in FIGS. 3A, 3B , 4 A, 4 B, 5 A, 5 B, and 6 .
- step 730 having determined that the desired geometry change between the stomach and the median arcuate ligament (represented by first tissue 122 and second tissue 124 ) is achieved and while continuing to hold tension on suture 118 , the physician sets suture lock assembly 100 into the lock state by using retention handle 218 , as described in reference to FIGS. 4A and 4B , which causes the coils of extension spring 112 to relax and create a torturous path and, thus, clamp against suture 118 , as shown in FIGS. 4A and 4B .
- the physician sets suture lock assembly 100 into the cut state by using retract handle 214 , as described in reference to Figures SA and 5 B, which causes suture 118 to be cut as hole 234 passes underneath the edge of first slot 230 , which has a geometry suitable for cutting suture 118 , as shown in FIGS. 5A and 5B .
- Step 734 having secured suture lock assembly 100 against first tissue 122 and having cut suture 118 , the physician releases retention jaw 226 from proximal endcap 116 of suture lock assembly 100 , which allows all instrumentation, such as lock actuating device 200 and the endoscope, and the surplus length of suture 118 , to be withdrawn from the patient, while suture 118 remains firmly clamped, as shown in FIG. 6 .
- Method 700 ends.
- FIG. 8 illustrates a perspective view of a suture lock assembly 800 in accordance with a second embodiment of the invention.
- Suture lock assembly 800 includes a cylindrical-shaped lock body 810 that further includes a plurality of suture channels 812 that run therethrough, and which have an associated plurality of locking holes 814 arranged on the outer surface of lock body 810 .
- Suture lock assembly 800 further includes a lock sleeve 816 that further includes a cavity 818 (shown in FIGS. 9 and 10 ) within which lock body 810 is inserted.
- Lock body 810 further includes a first groove 824 and a second groove 826 , which are detents formed around the outer perimeter of lock body 810 .
- Lock sleeve 816 further includes a first locking ring 820 and a second locking ring 822 , which are raised regions protruding from the inside perimeter of cavity 818 that are sized to lock within the detents formed by first groove 824 and second groove 826 of lock body 810 .
- suture 118 which is anchored to second tissue 124 with T-tag 126 passes through first tissue 122 and into one of the suture channels 812 , and exits lock body 810 via one of associated locking holes 814 . Only a small portion of the distal end of lock body 810 is inserted into cavity 818 , such that locking holes 814 are not within cavity 818 of lock sleeve 816 .
- Lock body 810 and lock sleeve 816 are formed of, for example, molded plastic or stainless steel.
- FIG. 9 illustrates a cross-sectional view of a suture lock assembly 800 and shows suture 118 passing through one of the suture channels 812 and existing lock body 810 .
- FIGS. 8 and 9 are representative of suture lock assembly 800 in the default, unlocked state wherein one or more sutures 118 may be threaded freely through lock body 810 .
- first locking ring 820 of lock sleeve 816 is engaged within second groove 826 of lock body 810 , as shown in FIGS. 8 and 9 .
- FIG. 10 illustrates a cross-sectional view of a suture lock assembly 800 in a locked state wherein or more sutures 118 is threaded through lock body 810 and locked therein. More specifically, in the lock state, lock sleeve 816 is pushed over the entire length of lock body 810 , such that suture 118 is clamped between the outer surface of lock body 810 and the wall of cavity 818 of lock sleeve 816 , after which any surplus suture 118 material is cut, which leaves suture lock assembly 800 secured against first tissue 122 .
- suture lock assembly 800 for coupling lock sleeve 816 to lock body 810 are exemplary only and are not limited to first locking ring 820 , second locking ring 822 , first groove 824 , and second groove 826 . Any well-known coupling method that allows a default and lock state by sliding lock sleeve 816 upon lock body 810 may be used.
- suture lock assembly 800 is suitably small enough to allow it to pass through the working channel of various endoscopic and ultrasound devices, which is typically between 2.8 and 3.4 mm in diameter. See Table 2 for example dimensions of suture lock assembly 800 . TABLE 2 Example dimensions of suture lock assembly 800 Example Dimension Lock body 810 length 0.35 in Lock body 810 outside diameter 0.07 in Suture channels 812 diameter 0.015 in Lock sleeve 816 length 0.38 in Lock sleeve 816 inside diameter 0.07 in Suture lock assembly 800 overall length 0.39 in when locked
- suture lock assembly 800 in combination with suture 118 , T-tag 126 , first tissue 122 , and second tissue 124 , is generally the same as described in FIG. 7 , in reference to suture lock assembly 100 , in that it is fed down the working channel of an endoscope and into, for example, a patient's stomach, in much the same manner.
- suture lock assembly 800 requires no special actuating device; instead, it may be pushed through the working channel of an endoscope with, for example, the tip of a standard catheter.
- its use differs from suture lock assembly 100 , in that suture lock assembly 800 requires separate instrumentation for cutting the one or more sutures 118 engaged therein.
- FIGS. 11A and 11B illustrate an alternative locking device similar in function to those previously mentioned.
- the locking device of FIGS. 11A and 11B are designed to lock onto suture 118 , when used in conjunction with the endoscope.
- the locking device of FIGS. 11A and 11B may be placed on suture 118 attached to T-tag 126 , that has been placed through first tissue 122 and second tissue 124 using the previously-described technique.
- This embodiment comprises a tubular sleeve 1100 , a flap 1105 , and a detent 1120 .
- Tubular sleeve 1100 may have an outer diameter of about 2.6 mm and an inner diameter of about 1 mm, and may be injection molded from a suitable polymer, such as polycarbonate, as a single piece or as separate pieces which are then fused together to form a unitary structure.
- flap 1105 In a resting state, flap 1105 is biased toward contact with detent 1120 . Therefore, to load suture 118 into tubular segment 1100 , an introducer 1130 may be used to create space between flap 1105 and detent 1120 as shown in FIG. 11A .
- Introducer 1130 may be placed into tubular segment 1100 by pushing from a distal end 1122 of tubular segment 1100 , so that flap is moved away from detent 1120 . Suture may be placed through a central lumen 1135 of introducer 1130 , so that ultimately suture 118 is positioned within tubular segment 1100 . Introducer 1130 is then removed by pulling it out of tubular segment 1100 from a proximal end 1133 , so that introducer 1130 is not trapped between tubular segment 1100 and second tissue 124 .
- tubular segment 110 may be pushed along suture 118 toward second tissue 124 with a pusher 1140 especially designed for that purpose, as shown in FIG. 11B .
- Tension on suture 118 acts to pull flap 1105 partially away from detent 1120 during advancement.
- pusher 1140 is withdrawn and flap 1105 traps suture 118 against detent 1120 so that tubular segment 1100 is held securely in place.
- FIGS. 12A and 12B show another alternative concept for locking onto suture 118 .
- FIG. 12A shows a perspective view of a clip 1200 comprising a first gripping surface 1210 , a second gripping surface 1220 , an opening 1230 , and a clasp 1240 .
- clip 1200 is open as shown in FIG. 12A , so that suture 118 can pass freely through opening 1230 .
- Clip 1200 may be placed on suture 118 attached to T-tag 126 , that has been placed through first tissue 122 and second tissue 124 using the previously-described technique.
- Clip 1200 may be placed onto suture 118 so that clasp 1280 is directed toward second tissue 124 and opening 1230 is directed toward the user.
- Clip 1200 may be pushed down suture 118 using a long flexible tube, such as an endoscope.
- a horn 1270 including a tapered surface 1272 may be used to apply force at a proximal end of clip 1200 , so that first gripping surface 1210 mates with second gripping surface 1220 to securely hold onto suture 118 , while clasp 1280 holds clip 1200 closed.
- Clip 1200 may be made from any suitable polymer material, such as nylon.
- Clip 1200 may be injection molded as a unitary piece with a “living hinge” that biases the part to an open position in which a first gripping surface 1210 is held away from second gripping surface 1220 in a default open state or assembled from multiple pieces.
Abstract
Suture holding devices and methods are disclosed, including devices and methods useful in performing a transoral surgical procedure, such as a posterior gastropexy procedure. A device is disclosed which can be used by a physician in a medical procedure to automatically lock and cut a suture in one motion and without the need for additional cutting instrumentation, rather than perform separate locking and cutting actions.
Description
- This application claims priority to and incorporates by reference the following applications: U.S. Provisional Application 60/571,117 filed May 14, 2004; U.S. provisional Application 60/571,119 filed May 14, 2004; and U.S. Provisional Application 60/571,000 filed May 14, 2004.
- This invention relates to endoscopic suturing devices and methods, including devices and methods which may pass through or be employed in connection with the working channel of various endoscopic and ultrasound devices.
- Application of sutures in the gastrointestinal tract is required for several different types of medical procedures, for example, for transoral endoscopic valvuloplasty for gastroesophageal reflux disease (GERD), gastroplasty, fundoplication, anterior gastropexy, posterior gastropexy, suturing esophageal perforations, or closure of the esophageal side of the tracheo-esophageal fistula. Traditionally, these procedures are performed by physicians, such as gastroenterologists or surgeons, either by laparoscopy or open surgical techniques. Such procedures are invasive, as laparoscopy requires that small access incision(s) be made in the body of the patient, through which a laparoscope and other surgical enabling tools are provided, while open surgical techniques are traditionally invasive and can have complications and cause long patient recovery periods.
- The solution to these problems is to perform these medical procedures through the gastroesophageal tract via the mouth or other naturally occurring orifice. Already available flexible endoscopes, commonly called gastroscopes, can be provided through the gastroesophageal tract and enable illumination and visualization of tissue along the gastroesophageal tract on a video display for diagnostic purposes. These flexible endoscopes also provide an instrumentation means for applying sutures in tissue, such as in the wall of the stomach. What is needed are improved methods of providing a totally transoral surgical procedure, such as a posterior gastropexy procedure, and thereby avoid more invasive laparoscopic procedures.
- New endoscopic suturing methods performed through the gastroesophageal tract as an alternative to the invasive laparoscopic method of, for example, a posterior gastropexy procedure, are currently being developed. For example, suturing methods under the control of endoscopic ultrasound (EUS) are being evaluated. EUS is a procedure that combines endoscopy and ultrasound. In particular, a Mar. 14, 2003 publication authored by Fritscher-Ravens, Mosse, Mukherjee, Yazaki, Park, Mills, and Swain, entitled, “Transgastric gastropexy and hiatal hernia repair for GERD under EUS control: a porcine model,” (American Society for Gastrointestinal Endoscopy) describes how endoluminal operations for gastroesophageal reflux are currently limited by the inability of the surgeon to visualize and manipulate structures outside the wall of the gut. The publication describes a way to define the EUS anatomy of structures outside the gut that influence reflux, to place stitches in the median arcuate ligament, to perform posterior gastropexy, and to test the feasibility of crural repair, under EUS control, in pigs. More specifically, by using a linear-array EUS, the median arcuate ligament and part of the right crus were identified and punctured with a needle, which served as a carrier for a tag and suture. These were anchored into the muscle. An endoscopic sewing device was used, which allowed stitches to be placed through a 2.8-mm accessory channel to any predetermined depth.
- The publication also describes new methods of knot tying and suture cutting through the 2.8-mm channel of the EUS. More specifically, stitches were placed through the gastric wall into the median arcuate ligament, and one stitch was placed just beyond the wall of the lower esophageal sphincter. The stitches were tied together and locked against the gastric wall, and the surplus length of suture material was then cut and removed. While this publication describes a suitable transgastric gastropexy and hiatal hernia repair procedure, further improvements in methodology and equipment to perform such procedures would be beneficial. For example, the publication describes a process for locking and cutting the suture from inside the stomach. However, the suture requires that a separate suture cutting step, along with its associated cutting instrumentation, be available via the working channel of the endoscope. This may result in multiple passes of instrumentation back and forth through the working channel of the endoscope. What is needed is a way to both lock and cut a suture automatically with a single device and thereby simplify the medical procedure, such as a posterior gastropexy procedure.
- Additionally, the locking mechanism described in the publication is too large to pass through the working channel of an endoscope and, thus, it must be inserted into the patient separately from the endoscope, which again adds complexity to the medical procedure. What is needed are suture locking and cutting mechanisms that are small enough to pass through the working channel of various endoscopic and ultrasound devices (typical working channel diameter is 2.8-3.4 mm).
- Applicants recognize the desirability of providing improved methods of performing a totally transoral surgical procedure, such as a posterior gastropexy procedure, and thereby avoid more-invasive laparoscopic procedures. Applicants also recognize the desirability of providing a single mechanism for automatically locking and cutting a suture and thereby simplifying medical procedures, such as, but not limited to, a posterior gastropexy procedure; and the desirability of providing suture locking and cutting mechanisms that are small enough to pass through the working channel of various endoscopic and ultrasound devices.
- Certain embodiments of the present invention are directed to providing improved methods of performing a totally transoral surgical procedure, such as a posterior gastropexy procedure, and thereby avoiding more-invasive laparoscopic procedures. One embodiment of the present invention provides a device and method that allows a physician in a medical procedure to automatically lock and cut a suture in one motion and without the need for additional cutting instrumentation, rather than perform separate locking and cutting actions.
- In one embodiment of the invention, a suture lock assembly in combination with a lock actuating device is provided. The lock comprises an extension spring arranged between two endcaps, wherein one or more sutures are locked within the coils thereof. Extending the extension spring allows for one or more sutures to be threaded therethrough and, by relaxing the extension spring, provides a clamping action upon the sutures and a torturous path within the coils. The lock actuating device provides a cutting mechanism. Furthermore, both the suture lock assembly, in combination with a lock actuating device, are suitably small enough to pass through the working channel of various endoscopic and ultrasound devices.
- In another embodiment of the invention, a suture lock assembly is provided that forms a hollow body, within which a clamp device is engaged and through which one or more sutures is threaded. Depending upon the slidable position of the clamp device within the body, the suture within the clamp device is engaged to clamp the suture permanently. The suture lock assembly of this embodiment is likewise suitably small enough to pass through the working channel of various endoscopic and ultrasound devices.
- The various embodiments of the invention can be employed with various types of suture, including without limitation monofilament suture and braided suture.
- While the novel features of the invention are set forth with particularity in the appended claims, the invention, in all its embodiments, may be more fully understood with reference to the following description and accompanying drawings.
-
FIG. 1A illustrates a perspective view of a suture lock assembly in accordance with a first embodiment of the invention; -
FIG. 1B illustrates a cross-sectional view of the suture lock assembly in accordance with a first embodiment of the invention; -
FIG. 2 illustrates a side view of an exemplary lock actuating device according to the first embodiment; -
FIGS. 3A and 3B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the default state; -
FIGS. 4A and 4B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the lock state; -
FIGS. 5A and 5B illustrate a side view and a top view, respectively, of the distal end of the lock actuating device with the suture lock assembly of the first embodiment engaged therein in the cut state; -
FIG. 6 illustrates a side view of the suture lock assembly of the first embodiment engaged therein in the release state; -
FIG. 7 illustrates a flow diagram of an example method of using the suture lock assembly of the first embodiment in combination with the lock actuating system; -
FIG. 8 illustrates a perspective view of a suture lock assembly in accordance with a second embodiment of the invention. -
FIG. 9 illustrates a cross-sectional view of the suture lock assembly of the second embodiment in the unlocked state. -
FIG. 10 illustrates a cross-sectional view of the suture lock assembly of the second embodiment in the locked state. -
FIGS. 11A and 11B illustrate cross section views of an alternative locking device with a one-way flap inside a tubular segment, in a loading state, and a locked state, respectively. -
FIGS. 12A and 12B show a cross section view of alternative one-piece clip in a default state, and a cross section view of the one-piece clip in a locked state, respectively. -
FIG. 1A illustrates a perspective view of asuture lock assembly 100 in accordance with a first embodiment of the invention.Suture lock assembly 100 includes anextension spring 112 arranged between adistal endcap 114 and aproximal endcap 116. -
Extension spring 112 is formed of any nontoxic, noncorrosive metal, such as stainless steel, anddistal endcap 114 andproximal endcap 116 are formed of, for example, molded plastic or stainless steel. Also shown inFIG. 1 is asuture 118 threaded first through ahole 120 indistal endcap 114 and then through multiple coils ofextension spring 112, whereinsuture 118 is clamped because of the pressure of the coils and the tortuous path within the coils.Suture lock assembly 100 is not limited to asingle suture 118 installed therein; a plurality ofsutures 118 may be engaged within a singlesuture lock assembly 100. -
FIG. 1B illustrates a cross-sectional view ofsuture lock assembly 100 taken along line AA ofFIG. 1A . This view shows thatproximal endcap 116 further includes ahollow channel 121 that runs through its center. Furthermore,hole 120 indistal endcap 114 is angled from the center of an outer end ofdistal endcap 114 toward the sidewall ofdistal endcap 114, which thereby allowssuture 118 to exitdistal endcap 114 external toextension spring 112.Distal endcap 114 andproximal endcap 116 may be insert-molded ontoextension spring 112 or use other methods or procedures of providing a smooth, trauma free extension of spring coils. - In operation,
suture 118 is threaded first throughhole 120 indistal endcap 114;extension spring 112 is then extended andsuture 118 is threaded through multiple coils ofextension spring 112;extension spring 112 is then relaxed, which thereby applies a tortuous path in addition to a clamping or locking action uponsuture 118 between the coils thereof. The overall diameter ofsuture lock assembly 100 is suitably small enough to allow it to pass through the working channel of various endoscopic and ultrasound devices, which is typically between 2.8 and 3.4 mm in diameter. See Table 1 for example dimensions ofsuture lock assembly 100.TABLE 1 Example dimensions of suture lock assembly 100Example Dimension Suture lock assembly 100 overall length 0.70 in Extension spring 112 outside diameter0.060 in Extension spring 112 inside diameter0.040 in Distal endcap 114 outside diameter0.07 in Distal endcap 114 length0.15 in Proximal endcap 116 outside diameter0.07 in Proximal endcap 116 length0.125 in Hollow channel 121 diameter0.04 in Hole 120 diameter0.04 in Hole 120 angle45 degrees -
FIG. 2 illustrates a side view of alock actuating device 200, which is exemplary only and representative of any suitable actuating device for use withsuture lock assembly 100. In this example,lock actuating device 200 includes abody 210 that has aknob 212 arranged at its proximal end for grasping by the user. Mechanically coupled tobody 210 is a retracthandle 214, which has a retracthandle body 216 and aretention handle 218 that is slidably arranged within retracthandle body 216. Furthermore, acompression spring 220 is mechanically coupled between aspring retainer 222, which is coupled toknob 212, and the proximal end of retracthandle body 216. Mechanically coupled to the distal end of retracthandle body 216 is a hollowretractable sleeve 224, within which is first arranged ahollow retention sleeve 225, which has aretention jaw 226 at its distal end. Furthermore, arranged withinretention sleeve 225 is anactuating shaft 228.FIG. 2 also shows that arranged within the distal end ofretractable sleeve 224 is afirst slot 230 that is aligned opposite asecond slot 232. Also, arranged within the distal end ofretention sleeve 225 is ahole 234 that is aligned opposite aslot 236. -
Actuating shaft 228 of a fixed length is mechanically coupled at one end to the distal end ofspring retainer 222 while passing throughspring retainer 222.Actuating shaft 228 passes through a hollow channel within retracthandle body 216, then passes through the hollow channel ofretention jaw 226 withinretractable sleeve 224. The tip ofactuating shaft 228 extends through an opening at the distal end ofretention jaw 226 withinretractable sleeve 224. Using retracthandle 214 and retention handle 218,retractable sleeve 224 andretention sleeve 225 are slidable along the length ofactuating shaft 228. As a result, the relative axial position ofretractable sleeve 224,retention jaw 226, and actuatingshaft 228 may vary one to another under user control.Lock actuating device 200 may include well-known mechanical methods and elements (not shown) for holdingretractable sleeve 224 andretention jaw 226 at various positional states. - The operation of
suture lock assembly 100 in combination withlock actuating device 200 for automatically locking and cutting a suture includes a sequential transition from a default state (i.e., undeployed state) to a lock state, a cut state and, finally, a release state (i.e., deployed state), as described in reference toFIGS. 3A, 3B , 4A, 4B, 5A, 5B, 6, and 7. Additionally,FIGS. 3A, 3B , 4A, 4B, 5A, 5B, and 6 showsuture lock assembly 100 in use and, therefore, it includessuture 118, which runs through the center ofsuture lock assembly 100 and approximates afirst tissue 122 and asecond tissue 124.Suture 118 is anchored tosecond tissue 124 with a T-tag 126, which is a well-known medical device for anchoring a suture into body tissue. -
FIGS. 3A and 3B illustrate a side view and a top view, respectively, of the distal end oflock actuating device 200 withsuture lock assembly 100 engaged therein in the default state, which is described as follows. - Default state: In the default or undeployed state,
extension spring 112 is extended suitably to allowsuture 118 to slide freely through its coils. This is accomplished by the physician's passingactuating shaft 228 throughhollow channel 121 ofproximal endcap 116, then through the center ofextension spring 112, until the tip ofactuating shaft 228 abuts the inner surface ofdistal endcap 114. By usingretention handle 218, which is attached to the proximal end ofretention sleeve 225, the physician extendsretention jaw 226 to allow it to gripproximal endcap 116 and then pullproximal endcap 116 into the tip ofretractable sleeve 224, as shown inFIGS. 3A and 3B , which thereby extendsextension spring 112, relative to the tip ofactuating shaft 228. The distance between the tip ofactuating shaft 228 and the tip ofretractable sleeve 224 is predetermined to suitably extendextension spring 112. Additionally,suture 118 is threaded first throughhole 120 indistal endcap 114, then within the extended coils ofextension spring 112 is wrapped multiple times around actuatingshaft 228, throughfirst slot 230 ofretractable sleeve 224, throughhole 234 ofretention sleeve 225, passes around actuatingshaft 228, throughslot 236 ofretention sleeve 225 and, finally, throughsecond slot 232 ofretractable sleeve 224. -
FIGS. 4A and 4B illustrate a side view and a top view, respectively, of the distal end oflock actuating device 200 withsuture lock assembly 100 engaged therein in the lock state, which is described as follows. - Lock state: In the lock state,
extension spring 112 is relaxed, which allows its coils to clamp againstsuture 118 and thereby preventsuture 118 from sliding freely between the coils ofextension spring 112. By usingretention handle 218, which is attached to the proximal end ofretention sleeve 225, the physician extendsretention jaw 226 while grippingproximal endcap 116 in a direction towarddistal endcap 114 and while maintaining the relative distance between the tip ofactuating shaft 228 and the tip ofretractable sleeve 224, as set in the default state. Although the relative position ofhole 234 and slot 236 tofirst slot 230 andsecond slot 232, respectively, is changed,suture 118 is intact and passing freely throughfirst slot 230 ofretractable sleeve 224, throughhole 234 ofretention sleeve 225, passes around actuatingshaft 228, throughslot 236 ofretention sleeve 225, and throughsecond slot 232 ofretractable sleeve 224, as shown inFIGS. 4A and 4B . -
FIGS. 5A and 5B illustrate a side view and a top view, respectively, of the distal end oflock actuating device 200 withsuture lock assembly 100 engaged therein in the cut state, which is described as follows. - Cut state: In the cut state, the relative distance between the tip of
actuating shaft 228 and the tip ofretention jaw 226 is maintained, as set in the lock state. By using retracthandle 214, which is attached to the proximal end ofretractable sleeve 224, the physician retracts tip ofretractable sleeve 224 in a direction away from the tip ofretention jaw 226, which causes the position ofhole 234 and slot 236 withinretention sleeve 225 to change, relative tofirst slot 230 andsecond slot 232, respectively, such thatsuture 118 withinhole 234 is cut ashole 234 passes underneath the edge offirst slot 230, which has a ground edge suitable for cuttingsuture 118. -
FIG. 6 illustrates a side view ofsuture lock assembly 100 in the release state, which is described as follows. - Release state: In the release state, the physician manipulates the grasp of
retention jaw 226 andproximal endcap 116 is released, which allows all instrumentation, such aslock actuating device 200 and the endoscope, as well as the surplus length ofsuture 118, to be removed.Extension spring 112 remains relaxed and, thus, the locking action uponsuture 118 is maintained indefinitely within the patient. - In an alternative embodiment, rather than wrapping the
suture 118 multiple times aroundshaft 228 within the extended coils ofspring 112, thesuture 118 can be manually threaded through or otherwise positioned between the extended coils, such as in a serpentine fashion, so that the coils hold the suture when the coils are permitted to close together. Such manual positioning of the suture through the coils may be employed if theshaft 228 is not employed or is otherwise not positioned within thespring 112 when the suture is positioned with respect to the coils ofspring 112. -
FIG. 7 illustrates a flow diagram of anexample method 700 of usingsuture lock assembly 100 in combination withlock actuating device 200 in accordance with the invention. More specifically,method 700 provides an example of a posterior gastropexy procedure that usessuture lock assembly 100 of the present invention. The use ofsuture lock assembly 100 is not limited to a posterior gastropexy procedure;suture lock assembly 100 may be used in any of various, similar medical procedures. Furthermore,method 700 is not limited to asingle suture 118 installed withinsuture lock assembly 100; a plurality ofsutures 118 may be engaged within a singlesuture lock assembly 100. - At
step 710, a physician passes an EUS endoscope through a patient's mouth and esophagus and into the stomach. Example EUS endoscopes include endoscope model GF-UC160P-AT8 manufactured by Olympus Europe (Hamburg, Germany) and endoscope model EG-3630U manufactured by Pentax Medical Company (Orangeburg, N.Y.). The working channel of the EUS endoscope is preloaded with a standard EUS needle, such as is manufactured by Wilson-Cook (Winston-Salem, N.C.), that serves as a carrier for a tag and suture, such as T-tag 126 andsuture 118. Suture 118 may run either through the needle or outside the needle, but still inside the working channel of the EUS endoscope. - At
step 712, under the guidance of the EUS endoscope, the physician locates and identifies structures outside the stomach wall and selects a fixation point, such as the median arcuate ligament. - At
step 714, under the guidance of the EUS endoscope, the physician pushes the EUS needle, which is carrying T-tag 126 andsuture 118, through the stomach wall, which is represented byfirst tissue 122 inFIGS. 3A, 3B , 4A, 4B, 5A, 5B, and 6. - At
step 716, under the guidance of the EUS endoscope, the physician deploys and affixes T-tag 126, withsuture 118 attached thereto, to the fixation point, such as to the median arcuate ligament, which is represented bysecond tissue 124 inFIGS. 3A, 3B , 4A, 4B, 5A, 5B, and 6. - At
step 718, the physician withdraws the EUS endoscope and associated instrumentation from the patient, but leaves a length ofsuture 118 still threaded through the patient's gastroesophageal tract and anchored to second tissue 124 (e.g., median arcuate ligament). The length ofsuture 118 extends out of the patient's mouth and is accessible to the physician. - At
step 720, the physician threads the length ofsuture 118 that is extending out of the patient's mouth into the distal end and out of the proximal end of the working channel of a standard endoscope that has a standard vision system (i.e., not an EUS endoscope). - At
step 722, while holding tension onsuture 118, the physician passes the endoscope through the patient's mouth and esophagus and into the stomach. A length ofsuture 118 is left extending out of the proximal end of the working channel of the endoscope and is accessible to the physician. - At
step 724, the physician loadssuture lock assembly 100 into the distal end oflock actuating device 200 and setssuture lock assembly 100 into the default state, as described in reference toFIGS. 3A and 3B . - At
step 726, withsuture lock assembly 100 in the default state and loaded intolock actuating device 200, the physician first threads the length ofsuture 118 that is extending out of the proximal end of the endoscope throughhole 120 indistal endcap 114, then within the extended coils ofextension spring 112 is wrapped multiple times around actuatingshaft 228, then threaded throughhole 234 ofretention sleeve 225, then threaded throughfirst slot 230 ofretractable sleeve 224, then threaded throughsecond slot 236 ofretention sleeve 225 and, finally, threaded throughsecond slot 232 ofretractable sleeve 224, as shown inFIGS. 3A and 3B . - At
step 728, while holding tension onsuture 118, which is extending out ofsecond slot 232 ofretractable sleeve 224, the physician passes thesuture lock assembly 100 andretractable sleeve 224 oflock actuating device 200 through the working channel of the endoscope and into the patient's stomach.Suture lock assembly 100 is sliding freely alongsuture 118 in the default state, untildistal endcap 114 is firmly abutted against the inside of the stomach wall, which is represented byfirst tissue 122 inFIGS. 3A, 3B , 4A, 4B, 5A, 5B, and 6. - At
step 730, having determined that the desired geometry change between the stomach and the median arcuate ligament (represented byfirst tissue 122 and second tissue 124) is achieved and while continuing to hold tension onsuture 118, the physician setssuture lock assembly 100 into the lock state by usingretention handle 218, as described in reference toFIGS. 4A and 4B , which causes the coils ofextension spring 112 to relax and create a torturous path and, thus, clamp againstsuture 118, as shown inFIGS. 4A and 4B . - At
step 732, having securedsuture lock assembly 100 againstfirst tissue 122 withsuture 118, the physician setssuture lock assembly 100 into the cut state by using retracthandle 214, as described in reference to Figures SA and 5B, which causessuture 118 to be cut ashole 234 passes underneath the edge offirst slot 230, which has a geometry suitable for cuttingsuture 118, as shown inFIGS. 5A and 5B . - At
step 734, having securedsuture lock assembly 100 againstfirst tissue 122 and having cutsuture 118, the physician releasesretention jaw 226 fromproximal endcap 116 ofsuture lock assembly 100, which allows all instrumentation, such aslock actuating device 200 and the endoscope, and the surplus length ofsuture 118, to be withdrawn from the patient, whilesuture 118 remains firmly clamped, as shown inFIG. 6 .Method 700 ends. -
FIG. 8 illustrates a perspective view of asuture lock assembly 800 in accordance with a second embodiment of the invention.Suture lock assembly 800 includes a cylindrical-shapedlock body 810 that further includes a plurality ofsuture channels 812 that run therethrough, and which have an associated plurality of lockingholes 814 arranged on the outer surface oflock body 810.Suture lock assembly 800 further includes alock sleeve 816 that further includes a cavity 818 (shown inFIGS. 9 and 10 ) within which lockbody 810 is inserted.Lock body 810 further includes afirst groove 824 and asecond groove 826, which are detents formed around the outer perimeter oflock body 810.Lock sleeve 816 further includes afirst locking ring 820 and asecond locking ring 822, which are raised regions protruding from the inside perimeter ofcavity 818 that are sized to lock within the detents formed byfirst groove 824 andsecond groove 826 oflock body 810. - Also shown in
FIG. 8 issuture 118, which is anchored tosecond tissue 124 with T-tag 126 passes throughfirst tissue 122 and into one of thesuture channels 812, and exits lockbody 810 via one of associated locking holes 814. Only a small portion of the distal end oflock body 810 is inserted intocavity 818, such that lockingholes 814 are not withincavity 818 oflock sleeve 816.Lock body 810 and locksleeve 816 are formed of, for example, molded plastic or stainless steel. -
FIG. 9 illustrates a cross-sectional view of asuture lock assembly 800 and showssuture 118 passing through one of thesuture channels 812 and existinglock body 810.FIGS. 8 and 9 are representative ofsuture lock assembly 800 in the default, unlocked state wherein one ormore sutures 118 may be threaded freely throughlock body 810. In the default or unlocked state first lockingring 820 oflock sleeve 816 is engaged withinsecond groove 826 oflock body 810, as shown inFIGS. 8 and 9 . -
FIG. 10 illustrates a cross-sectional view of asuture lock assembly 800 in a locked state wherein ormore sutures 118 is threaded throughlock body 810 and locked therein. More specifically, in the lock state,lock sleeve 816 is pushed over the entire length oflock body 810, such thatsuture 118 is clamped between the outer surface oflock body 810 and the wall ofcavity 818 oflock sleeve 816, after which anysurplus suture 118 material is cut, which leavessuture lock assembly 800 secured againstfirst tissue 122. In order to achieve the locked state enough force is applied to locksleeve 816 againstlock body 810 such thatfirst locking ring 820 oflock sleeve 816 disengages from withinsecond groove 826 oflock body 810. In doing so,lock sleeve 816 slides uponlock body 810 untilfirst locking ring 820 andsecond locking ring 822 are engaged withinfirst groove 824 andsecond groove 826, respectively, oflock body 810, as shown inFIG. 10 . The mechanical features ofsuture lock assembly 800 forcoupling lock sleeve 816 to lockbody 810 are exemplary only and are not limited tofirst locking ring 820,second locking ring 822,first groove 824, andsecond groove 826. Any well-known coupling method that allows a default and lock state by slidinglock sleeve 816 uponlock body 810 may be used. - The overall diameter of
suture lock assembly 800 is suitably small enough to allow it to pass through the working channel of various endoscopic and ultrasound devices, which is typically between 2.8 and 3.4 mm in diameter. See Table 2 for example dimensions ofsuture lock assembly 800.TABLE 2 Example dimensions of suture lock assembly 800Example Dimension Lock body 810 length 0.35 in Lock body 810 outside diameter0.07 in Suture channels 812 diameter0.015 in Lock sleeve 816 length0.38 in Lock sleeve 816 inside diameter0.07 in Suture lock assembly 800 overall length0.39 in when locked - The method of using
suture lock assembly 800, in combination withsuture 118, T-tag 126,first tissue 122, andsecond tissue 124, is generally the same as described inFIG. 7 , in reference tosuture lock assembly 100, in that it is fed down the working channel of an endoscope and into, for example, a patient's stomach, in much the same manner. However,suture lock assembly 800 requires no special actuating device; instead, it may be pushed through the working channel of an endoscope with, for example, the tip of a standard catheter. Additionally, its use differs fromsuture lock assembly 100, in thatsuture lock assembly 800 requires separate instrumentation for cutting the one ormore sutures 118 engaged therein. -
FIGS. 11A and 11B illustrate an alternative locking device similar in function to those previously mentioned. The locking device ofFIGS. 11A and 11B are designed to lock ontosuture 118, when used in conjunction with the endoscope. The locking device ofFIGS. 11A and 11B may be placed onsuture 118 attached to T-tag 126, that has been placed throughfirst tissue 122 andsecond tissue 124 using the previously-described technique. - This embodiment comprises a
tubular sleeve 1100, aflap 1105, and adetent 1120.Tubular sleeve 1100 may have an outer diameter of about 2.6 mm and an inner diameter of about 1 mm, and may be injection molded from a suitable polymer, such as polycarbonate, as a single piece or as separate pieces which are then fused together to form a unitary structure. In a resting state,flap 1105 is biased toward contact withdetent 1120. Therefore, to loadsuture 118 intotubular segment 1100, anintroducer 1130 may be used to create space betweenflap 1105 anddetent 1120 as shown inFIG. 11A .Introducer 1130 may be placed intotubular segment 1100 by pushing from adistal end 1122 oftubular segment 1100, so that flap is moved away fromdetent 1120. Suture may be placed through acentral lumen 1135 ofintroducer 1130, so that ultimately suture 118 is positioned withintubular segment 1100.Introducer 1130 is then removed by pulling it out oftubular segment 1100 from aproximal end 1133, so that introducer 1130 is not trapped betweentubular segment 1100 andsecond tissue 124. - After
introducer 1130 is removed, tubular segment 110 may be pushed alongsuture 118 towardsecond tissue 124 with apusher 1140 especially designed for that purpose, as shown inFIG. 11B . Tension onsuture 118 acts to pullflap 1105 partially away fromdetent 1120 during advancement. Whendistal end 1122 oftubular segment 1100 reachessecond tissue 124,pusher 1140 is withdrawn andflap 1105 traps suture 118 againstdetent 1120 so thattubular segment 1100 is held securely in place. -
FIGS. 12A and 12B show another alternative concept for locking ontosuture 118.FIG. 12A shows a perspective view of aclip 1200 comprising a firstgripping surface 1210, a secondgripping surface 1220, anopening 1230, and a clasp 1240. In a default state,clip 1200 is open as shown inFIG. 12A , so thatsuture 118 can pass freely throughopening 1230.Clip 1200 may be placed onsuture 118 attached to T-tag 126, that has been placed throughfirst tissue 122 andsecond tissue 124 using the previously-described technique.Clip 1200 may be placed ontosuture 118 so thatclasp 1280 is directed towardsecond tissue 124 andopening 1230 is directed toward the user.Clip 1200 may be pushed downsuture 118 using a long flexible tube, such as an endoscope. - To
lock clip 1200 ontosuture 118, ahorn 1270 including a taperedsurface 1272 may be used to apply force at a proximal end ofclip 1200, so that firstgripping surface 1210 mates with secondgripping surface 1220 to securely hold ontosuture 118, whileclasp 1280 holdsclip 1200 closed.Clip 1200 may be made from any suitable polymer material, such as nylon.Clip 1200 may be injection molded as a unitary piece with a “living hinge” that biases the part to an open position in which a firstgripping surface 1210 is held away from secondgripping surface 1220 in a default open state or assembled from multiple pieces. - While the present invention has been illustrated by description of various embodiments, it is not the intention of the applicants to restrict or limit the spirit and scope of the appended claims to such detail. Numerous other variations, changes, and substitutions will occur to those skilled in the art without departing from the scope of the invention. Moreover, the structure of each element associated with the present invention can be alternatively described as a means for providing the function performed by the element. It will be understood that the foregoing description is provided by way of example, and that other modifications may occur to those skilled in the art without departing from the scope and spirit of the appended Claims.
Claims (16)
1. A medical device for locking onto suture comprising:
a first endcap, wherein said first endcap includes a hole bored at an oblique angle to a central axis;
a second endcap; and
an extension spring extending from said first endcap to said second endcap.
2. The medical device of claim 1 wherein first endcap and said second endcap have an outer diameter of no more than about 0.07 inch.
3. The medical device of claim 1 wherein said hole has a diameter of about 0.04 inch, and is bored at an angle of about 45 degrees to the central axis.
4. A medical device for locking onto suture comprising:
an endcap; and
an extension spring associated with said endcap, wherein said spring coils are biased in a compressed state; and
a length of suture held by said spring.
5. The medical device of claim 4 wherein said endcap has an outer diameter of no more than about 0.07 inch.
6. The medical device of claim 4 wherein the suture is monofilament.
7. The medical device of claim 4 wherein the suture is braided.
8. A medical device comprising:
a first endcap, wherein said endcap includes a hole bored at an oblique angle to the central axis of said endcap;
a second endcap;
a spring disposed intermediate the first and second endcaps; and
a suture extending through said hole in said first endcap.
9. A method of holding suture comprising the steps of:
providing a first member having a suture receiving hole;
providing a second member associated with the first member, the second member comprising a plurality of coils;
providing a length of suture;
threading a suture through said hole in said first member;
spreading the coils of said second member; and
holding the suture with coils of the second member.
10. The method of claim 7 further comprising the step of:
spreading the coils apart to loosen tension in said suture.
11. A medical device for locking onto suture comprising:
a body portion, wherein said body portion includes at least one suture channel;
a lock sleeve positioned over an outer surface of said body portion;
wherein said lock sleeve has an inner surface that closely matches the outer surface of said body portion; and
a means for locking said body portion within said lock sleeve.
12. The medical device of claim 11 , wherein said locking means comprises a groove in said body portion and a ring projection in said locking sleeve.
13. The medical device of claim 11 , wherein there is a clearance of about 0.001 inch or less between the outer surface of said body portion and the inner surface of said locking sleeve.
14. A method of using a medical device to lock onto suture comprising the steps:
providing a device comprising a body portion, wherein said body portion includes at least one suture channel; a lock sleeve positioned over an outer surface of said body portion, wherein said lock sleeve has an inner surface that closely matches the outer surface of said body portion; and a means for locking said body portion within said lock sleeve;
threading a suture through said suture channel;
pushing said locking sleeve over said body portion to trap said suture in a tortuous path; and
locking said locking sleeve to said body portion.
15. A medical device for locking onto suture comprising:
a tubular sleeve including an inner channel;
a flap disposed within said inner channel of said tubular sleeve; and
a detent, wherein said detent is positioned within said inner channel such that said flap is biased to press against said detent.
16. A medical device for locking onto suture comprising:
A first gripping surface including a plurality of projections;
a second gripping surface, wherein said second grip surface is not in contact with said first grip surface in a default state; and
a clasp, wherein said clasp holds said first gripping surface against said second gripping surface in a locked state.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US11/127,955 US20060004410A1 (en) | 2004-05-14 | 2005-05-12 | Suture locking and cutting devices and methods |
Applications Claiming Priority (4)
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US57111904P | 2004-05-14 | 2004-05-14 | |
US57111704P | 2004-05-14 | 2004-05-14 | |
US57100004P | 2004-05-14 | 2004-05-14 | |
US11/127,955 US20060004410A1 (en) | 2004-05-14 | 2005-05-12 | Suture locking and cutting devices and methods |
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US20060004410A1 true US20060004410A1 (en) | 2006-01-05 |
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US11/127,515 Active 2029-07-01 US7785348B2 (en) | 2004-05-14 | 2005-05-12 | Devices and methods of locking and cutting a suture in a medical procedure |
US11/127,955 Abandoned US20060004410A1 (en) | 2004-05-14 | 2005-05-12 | Suture locking and cutting devices and methods |
US11/127,513 Active 2029-03-13 US8388653B2 (en) | 2004-05-14 | 2005-05-12 | T-type suture anchoring devices and methods of using same |
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US11/127,515 Active 2029-07-01 US7785348B2 (en) | 2004-05-14 | 2005-05-12 | Devices and methods of locking and cutting a suture in a medical procedure |
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US11/127,513 Active 2029-03-13 US8388653B2 (en) | 2004-05-14 | 2005-05-12 | T-type suture anchoring devices and methods of using same |
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WO2005112786A3 (en) | 2008-01-10 |
WO2005112785A3 (en) | 2008-02-07 |
WO2005112784A2 (en) | 2005-12-01 |
WO2005112786A2 (en) | 2005-12-01 |
US7785348B2 (en) | 2010-08-31 |
US20050277957A1 (en) | 2005-12-15 |
WO2005112785A2 (en) | 2005-12-01 |
US8388653B2 (en) | 2013-03-05 |
US20060025819A1 (en) | 2006-02-02 |
WO2005112784A3 (en) | 2007-12-06 |
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