Recherche Images Maps Play YouTube Actualités Gmail Drive Plus »
Connexion
Les utilisateurs de lecteurs d'écran peuvent cliquer sur ce lien pour activer le mode d'accessibilité. Celui-ci propose les mêmes fonctionnalités principales, mais il est optimisé pour votre lecteur d'écran.

Brevets

  1. Recherche avancée dans les brevets
Numéro de publicationUS20060036324 A1
Type de publicationDemande
Numéro de demandeUS 11/197,569
Date de publication16 févr. 2006
Date de dépôt3 août 2005
Date de priorité3 août 2004
Autre référence de publicationUS7658753, US7708765, US8002801, US8016860, US8043345, US9801666, US20060036246, US20060036256, US20100100130, US20100100133, US20100191288, US20120089186, US20160066964
Numéro de publication11197569, 197569, US 2006/0036324 A1, US 2006/036324 A1, US 20060036324 A1, US 20060036324A1, US 2006036324 A1, US 2006036324A1, US-A1-20060036324, US-A1-2006036324, US2006/0036324A1, US2006/036324A1, US20060036324 A1, US20060036324A1, US2006036324 A1, US2006036324A1
InventeursDan Sachs, Meir Rosenberg
Cessionnaire d'origineDan Sachs, Meir Rosenberg
Exporter la citationBiBTeX, EndNote, RefMan
Liens externes: USPTO, Cession USPTO, Espacenet
Adjustable spinal implant device and method
US 20060036324 A1
Résumé
A spine implant, in particular a stabilization or distraction device, is provided with an adjustable length.
Images(25)
Previous page
Next page
Revendications(20)
1. A spinal implant comprising a first portion configured to be coupled to a first bony portion; and a second portion configured to be coupled to a second bony portion,
wherein the spinal implant permits movement between the first bony portion and the second bony portion and wherein the spinal implant is adjustable to change an amount of said movement between said first bony portion and said second bony portion after the implant is implanted.
2. The spinal implant of claim 1 wherein the implant has a flexibility when implanted and wherein the implant is adjustable to change the flexibility after the implant is implanted.
3. The spinal implant of claim 1 wherein the implant is adjustable to decrease the amount of movement after implanted to reduce laxity of a joint between the first bony portion and the second bony portion.
4. The spinal implant of claim 1 wherein the implant comprises at least one cavity, and wherein the spinal implant is adjustable to change the amount of said movement by inserting a material in said cavity.
5. The spinal implant of claim 4 wherein the implant is adjustable to change the amount of said movement by inserting a curable polymer in said cavity.
6. The spinal implant of claim 4 wherein the implant comprises of plurality of cavities.
7. The spinal implant of claim 1 further comprising at least one insertable support member, wherein the implant is configured to receive said at least one support member, and wherein the spinal implant is adjustable to change the amount of movement by inserting said at least one support member.
8. The spinal implant of claim 7 wherein said at least one support member comprises a plurality of support members.
9. The spinal implant of claim 8 wherein each of said support members has a different flexibility.
10. The spinal implant of claim 7 wherein said support member comprises a spring.
11. The spinal implant of claim 10 wherein said support member has shock absorbing properties.
12. A spinal implant comprising:
a proximal portion configured to engage a spinous process of a first vertebra;
an elongate rod portion configured to extend adjacent a motion segment between the first vertebra and a second vertebra;
a distal portion configured to be fixed to a bony portion of a second vertebra; and
a motion portion configured to permit motion at the motion segment.
13. The spinal implant of claim 12 wherein the motion portion comprises a flexible portion located with the elongate rod portion.
14. The spinal implant of claim 12 wherein the flexible portion comprises a spring member.
15. The spinal implant of claim 14 wherein the flexible portion comprises a coil.
16. The spinal implant of claim 12 further comprising a spinous process reinforcement element.
17. The spinal implant of claim 16 wherein the proximal portion is attached to the spinous process reinforcement element.
18. The spinal implant of claim 12 wherein the distal portion is configured to be attached to a pedicle attachment device attached to the second bony portion.
19. The spinal implant of claim 12 further comprising a securing member configured to secure the proximal portion to the spinous process.
20. The spinal implant of claim 12 further comprising:
a second proximal portion configured to engage the spinous process of the first vertebra;
a second elongate rod portion configured to extend adjacent a second motion segment between the first vertebra and the second vertebra;
a second distal portion configured to be fixed to a bony portion of a second vertebra; and
a second motion portion configured to permit motion at the second motion segment.
Description
    RELATED APPLICATION DATA
  • [0001]
    The present application claims the priority of Provisional Application No. 60/598,882, filed Aug. 3, 2004 and entitled: Spine Treatment Devices and Methods.
  • FIELD OF THE INVENTION
  • [0002]
    The invention relates to devices to treat the spine, including but not limited to spinal stabilization devices, dynamic stabilizers, spinal deformity correction devices, devices to treat pain associated with the spine, and other spinal treatment devices.
  • BACKGROUND
  • [0003]
    Certain spine conditions, defects, deformities (e.g., scoliosis) as well as injuries may lead to structural instabilities, nerve or spinal cord damage, pain or other manifestations. Back pain (e.g., pain associated with the spinal column or mechanical back pain) may be caused by structural defects, by injuries or over the course of time from the aging process. For example, back pain is frequently caused by repetitive and/or high stress loads on or increased motion around certain boney or soft tissue structures. The natural course of aging leads to degeneration of the disc, loss of disc height, and instability of the spine among other structural manifestations at or around the spine. With disc degeneration, the posterior elements of the spine bear increased loads with disc height loss, and subsequently attempt to compensate with the formation of osteophytes and thickening of various stabilizing spinal ligaments. The facet joints may develop pain due to arthritic changes caused by increased loads. Furthermore, osteophytes in the neural foramina and thickening of spinal ligaments can lead to spinal stenosis, or impingement of nerve roots in the spinal canal or neural foramina. Scoliosis may also create disproportionate loading on various elements of the spine and may require correction, stabilization or fusion.
  • [0004]
    Pain caused by abnormal motion of the spine has long been treated by fixation of the motion segment. Spinal fusion is one way of stabilizing the spine to reduce pain. In general, it is believed that anterior interbody or posterior fusion prevents movement between one or more joints where pain is occurring from irritating motion. Fusion typically involves removal of the native disc, packing bone graft material into the resulting intervertebral space, and anterior stabilization, e.g., with intervertebral fusion cages or posterior stabilization, e.g., supporting the spinal column with internal fixation devices such as rods and screws. Internal fixation is typically an adjunct to attain intervertebral fusion. Many types of spine implants are available for performing spinal fixation, including the Harrington hook and rod, pedicle screws and rods, interbody fusion cages, and sublaminar wires.
  • [0005]
    Spinal stenosis pain or from impingement of nerve roots in the neural foramina has been treated by laminectomy and foraminotomy, and sometimes reinforced with rod and screw fixation of the posterior spine. More recently, surgeons have attempted to relieve spinal stenosis by distracting adjacent spinous processes with a wedge implant. Pain due to instability of the spine has also been treated with dynamic stabilization of the posterior spine, using elastic bands that connect pedicles of adjacent vertebrae.
  • [0006]
    The typical techniques for fusion, distraction, decompression, and dynamic stabilization require open surgical procedures with removal of stabilizing muscles from the spinal column, leading to pain, blood loss, and prolonged recovery periods after surgery due in part to the disruption of associated body structures or tissue during the procedures.
  • [0007]
    To reduce the invasiveness of fusion procedures, some methods of fusion have been proposed that do not require the extensive stripping of muscles away from the spinal column of earlier approaches. These involve posteriorly or laterally accessing the spine and creating spaces adjacent the spine for posterior stabilization. Some of these procedures include fusion via small working channels, created with dilator type devices or an external guide to create a trajectory channel between two ipsilateral neighboring pedicle screws. Also, placing support structures between adjacent pedicle screws and across a joint requires accessing and working in an area from a difficult angle (the support structure is typically oriented somewhat perpendicular to an angle of access and through muscle and connective tissue). Furthermore, these stabilization devices typically involve the use of 4 pedicle screws (each having a risk associated with it when placed in the spine), two on each side of a motion segment, and are not ideally suited for percutaneous stabilization required across more than one or two segments. Accordingly, it would be desirable to provide a less invasive or less disruptive segmental spine stabilization procedure and implant that has a reduced risk of damage or injury to associated tissue. It would also be desirable to provide an implanted posterior spine system that may be used to stabilize more than two motion segments in a less disruptive or less invasive manner.
  • [0008]
    One method of fusing a vertebra has been proposed using bilateral screws through the lamina using a posterior approach. However, geometric placement of the device is difficult and the procedure is considered dangerous because the laminar screws could enter through anteriorly into the spinal canal and cause nerve damage.
  • [0009]
    Accordingly, it would be desirable to provide a device that reduces the difficulties risks of the current procedures. It would also be desirable to provide a device that can be placed in a less disruptive or less invasive manner than commonly used procedures.
  • [0010]
    Unintended consequences of fixation include stress shielding of bone, as well as transfer of load to adjacent, still dynamic motion segments, and eventual degeneration of adjacent motion segments. Flexible stabilization of motion segments with plastic, rubber, super-elastic metals, fabric, and other elastic materials has been proposed to provide a degree of dynamic stabilization of some joints. Many of these constructs are not load bearing. Dynamic stabilization from pedicle screw to pedicle screw along the length of the spine has been proposed. However, this device has the disadvantage of requiring placement of 4 pedicle screws and associated tissue disruption.
  • [0011]
    Due to the risks, inconvenience, and recovery time required for surgical implantation of spinal devices, some patients may continue to prefer rigid fixation of a painful or degenerative motion segment over dynamic stabilization of the joint. In addition, doctors may be reluctant to recommend dynamic stabilization for patients with back pain, because it may not alleviate pain to a patient's satisfaction.
  • [0012]
    Furthermore, even in patients who experience good relief of pain with dynamic stabilizers, it is anticipated that while the onset of arthritic changes may be deferred, many patients will still eventually proceed to develop degeneration, and require fixation of the motion segment to obtain pain relief. Repeat spine procedures to remove one implant and replace it with another are associated with complications related to bleeding, surgical adhesions, destruction of bone, and other generic risks associated with surgical procedures. Accordingly, improved devices that address these issues would be desirable.
  • [0013]
    A number of spinal deformities exist where the spine is abnormally twisted and or curved. Scoliosis is typically considered an abnormal lateral curvature of the vertebral column.
  • [0014]
    Correction of scoliosis has been attempted a number of ways. Typically correction is followed by fusion. A Harrington rod has been used where a compressing or distracting rod is attached above and below a curved arch of the deformity. The spine is stretched longitudinally to straighten the spine as the rod is lengthened. The spine is then fused. The correction force in this device and in similar devices is a distraction force that may have several drawbacks including possible spinal cord damage, as well as the high loading on the upper and lower attachment sites. Nowadays, segmental hook and screw fixation exists for distraction and derotation corrective forces.
  • [0015]
    A Luque device has been used where the spine is wired to a rod at multiple fixation points along the rod and pulls the spine to the rod. The spine is pulled to the rod with a wire and the spine is then fused. This does not provide significant adjustment over time and requires fusion. Once completed this does not provide an opportunity for delayed adjustment over time. Anterior procedures also exist in the form of fusion and newer technology involving staples across the disc space that obviate the need for fusion but still correct the deformity. The corrective force is derotation with or without compression.
  • [0016]
    Accordingly it would be desirable to provide an improved corrective device for treating scoliosis or other deformities. It would also be desirable to provide a device that may be used without fusion.
  • [0017]
    Spine surgeons commonly use metallic or polymeric implants to effect or augment the biomechanics of the spine. The implants frequently are attached or anchored to bone of the spine. Sites typically considered appropriate for boney attachment have high density or surface area, such as, for example, the pedicle bone, the vertebral body or the cortical bone of the lamina. The spinous process contains thin walls of cortical bone, and thus, has been considered as not ideal for anchoring spinal implants as they may not support the implants under physiologic loads, or the intermittent high loads seen in traumatic situations. Fixation has been attempted from spinous process to spinous process with poor results.
  • [0018]
    A translaminar facet screw as used by some surgeons goes through the base of spinous process to access the cancellous bone of the lamina. A disadvantage of this device is that it is not suitable for attaching to a pedicle screw and the depth and angle during deployment can be very difficult to track or visualize, thus increasing the possibility that the screw would extend into the spinal canal. A facet screw is screwed between opposing facets of a zygapophyseal joint.
  • SUMMARY
  • [0019]
    One aspect of the present invention is directed to providing a device and method for alleviating discomfort and or deformity associated with the spinal column. Another aspect of the present invention is directed to providing a minimally invasive implant and method for alleviating discomfort associated with the spinal column. Another aspect of the present invention provides an anchoring device and method that requires less surrounding tissue damage or disruption. Another aspect of the present invention provides reinforcement of the spinous process for use in various spinal systems. Another aspect of the invention provides a minimally invasive, non-invasive, or remote adjustment or lengthening of an orthopedic device. Another aspect of the invention provides a minimally invasive, non-invasive, or remote adjustment, lengthening or shortening of a stabilization device. Another aspect of the present invention also provides an implant system and device suitable for minimally invasive, minimally disruptive and/or percutaneous posterior deployment across a plurality of motion segments and more than two motion segments. Different aspects of the invention may provide distraction forces to relieve pressure on certain structures, compression forces to fix or stabilize motion across structures, shock absorbing qualities to help relieve load from certain structures, and therapeutic activity to reduce inflammation and pain. Other aspects of the invention may supplement or bear load for degenerated, painful, or surgically removed joints, e.g., the facet joint. Another aspect of the invention may provide a method and system for treating deformities such as scoliosis. Other aspects of the invention may include sensors associated with implants or implanted at or near the bones, soft tissue, or joints of the spine and may provide feedback regarding the joint on an ongoing basis. The sensors may also be part of a feedback system that alters a property of an implant in response to sensing information. Another aspect of the invention may provide a device or method for delivering therapeutic substances at or near the spine.
  • [0020]
    In accordance with one aspect of the invention, a reinforcement structure is provided for supporting the spinous process and if desired, in addition, the lamina of a spine. The invention further provides a method and system for forming or implanting such structure in the spinous process or a region of cancellous bone in the lamina of a spine. The reinforcement system may include one or more systems of reinforcement and may be used before, during and/or after a spinal device (e.g. a stabilization, distraction or prosthetic device, etc.) is coupled to the spinous process.
  • [0021]
    Various aspects of the invention are set forth in the description and/or claims herein.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0022]
    FIG. 1A is a lateral posterior view of a vertebra with a reinforcement structure in accordance with the invention.
  • [0023]
    FIG. 1B is a side view of the vertebra and reinforcement structure of FIG. 1A.
  • [0024]
    FIG. 2A is a lateral posterior view of a vertebra with a reinforcement structure in accordance with the invention.
  • [0025]
    FIG. 2B is a side view of the vertebra and reinforcement structure of FIG. 2B.
  • [0026]
    FIG. 3A is a lateral posterior view of a vertebra with a reinforcement structure in accordance with the invention.
  • [0027]
    FIG. 3B is a side view of the vertebra and reinforcement structure of FIG. 3A.
  • [0028]
    FIG. 4A is a lateral posterior view of vertebrae with a reinforcement structure and implant in accordance with the invention.
  • [0029]
    FIG. 4B is a side view of the reinforcement structure and implant of FIG. 4A.
  • [0030]
    FIG. 4C is a top view of a reinforcement structure and implant in accordance with the invention.
  • [0031]
    FIG. 4D is a posterior view of the reinforcement structure and implant of FIG. 4C.
  • [0032]
    FIG. 5 is a posterior view of a reinforcement structure and implant in accordance with the invention.
  • [0033]
    FIG. 6 is a posterior view of a reinforcement structure and implant in accordance with the invention FIG. 7A is a top view of an implant implanted adjacent a motion segment in accordance with the invention.
  • [0034]
    FIG. 7B is a posterior view of the implant as shown in FIG. 7A.
  • [0035]
    FIG. 8A is a top view of an implant implanted through the lamina and the zygapophyseal joint in accordance with the invention.
  • [0036]
    FIG. 8B is a posterior view of the implant as shown in FIG. 8A.
  • [0037]
    FIG. 9A is a top view of a dynamic implant in accordance with the invention.
  • [0038]
    FIG. 9B is a posterior view of the implant as shown in FIG. 9A.
  • [0039]
    FIG. 10 is a schematic posterior portal cross sectional view of a reinforcement device and implant in accordance with the invention.
  • [0040]
    FIG. 11 is schematic posterior partial cross sectional view of a reinforcement device and implant in accordance with the invention.
  • [0041]
    FIG. 12A is an exploded perspective view of a reinforcement device and implant in accordance with the invention.
  • [0042]
    FIG. 12B is a top view of the reinforcement device and implant of FIG. 12A.
  • [0043]
    FIG. 13A is a schematic partial cross sectional view of an implant in accordance with the invention in a first position.
  • [0044]
    FIG. 13B is a schematic partial cross sectional view of the implant of FIG. 13A in a second, and implanted position.
  • [0045]
    FIG. 14A is a schematic partial cross sectional view of an implant in accordance with the invention in a first position.
  • [0046]
    FIG. 14B is a schematic partial cross sectional view of the implant of FIG. 14A in a second position.
  • [0047]
    FIG. 4B is a posterior lateral perspective view of a distraction system implanted in a spine in accordance with the invention.
  • [0048]
    FIG. 15 is a schematic side view of a connector of an implant in accordance with the invention.
  • [0049]
    FIG. 16 is a schematic side view of a connector of an implant in accordance with the invention.
  • [0050]
    FIG. 17 is a schematic perspective view of a connector in accordance with the invention.
  • [0051]
    FIG. 18 is a schematic side perspective view of a dynamic element in accordance with the invention.
  • [0052]
    FIG. 19 is a schematic side perspective view of an adjustable implant element in accordance with the invention.
  • [0053]
    FIG. 20 is a schematic side perspective view of an adjustable implant element in accordance with the invention.
  • [0054]
    FIG. 21 is a schematic side perspective view of an adjustable implant element in accordance with the invention.
  • [0055]
    FIG. 22A is a schematic view of a spine deformity correction device in accordance with the invention.
  • [0056]
    FIG. 22B is a cross section of FIG. 22A along the lines 22B-22B.
  • [0057]
    FIG. 22C is a schematic view of an adjustable pedicle attachment device in a first position in accordance with the invention.
  • [0058]
    FIG. 22D is a schematic view of the adjustable pedicle attachment device of FIG. 22C in accordance with the invention.
  • [0059]
    FIG. 22E is a schematic side partial cross sectional view of an alternative connector of the spine deformity device of FIG. 22A.
  • [0060]
    FIG. 22F is a schematic side partial cross-sectional view of an alternative connector of the spine deformity device of FIG. 22A.
  • [0061]
    FIG. 22G is a schematic side partial cross sectional view of an alternative connector of the spine deformity device of FIG. 22A.
  • [0062]
    FIG. 22H is a schematic side partial cross sectional view of an alternative connector of the spine deformity device of FIG. 22A.
  • [0063]
    FIG. 23A is a schematic side view of a spine deformity correction device in accordance with the invention.
  • [0064]
    FIG. 23B is a posterior view.
  • [0065]
    FIG. 24 is a schematic top view of an implant in accordance with the invention.
  • [0066]
    FIG. 25 is a schematic posterior lateral perspective view of a therapeutic substance delivery device in accordance with the invention.
  • [0067]
    FIG. 26 is a schematic posterior lateral perspective view of a therapeutic substance delivery device in accordance with the invention.
  • DETAILED DESCRIPTION
  • [0068]
    FIGS. 1A and 1B illustrate a reinforced posterior arch 100 of a first vertebra 91 of a spine 90, including a spinous process 101 and lamina 103. The first vertebra 100 of the spine 90 as illustrated includes a first spinous process 101 with a superior portion 102 having a posterior ridge 104 into which a hole 105 is drilled. The hole 105 may be drilled with a drill, a trocar, a large bore IV needle or similar sharp object through the external and relatively hard cortical bone, to reach the internal cancellous bone within the spinous process 101 and adjacent the lamina 103.
  • [0069]
    Once the cancellous bone is accessed, optionally, a tool such as a balloon tamp, or other expandable member or small crushing or drilling member is used to create a cavity 107 or cavities within the cancellous bone by compressing, crushing or drilling out the bone material. X-rays may be used to determine how far to drill into the bone. The cavity 107 may be in the spinous process, through to the base of the spinous process, or through the spinous process and into the lamina. In one embodiment the cavity is cone shaped or widens as it moves anteriorly towards the lamina.
  • [0070]
    A reinforcing material is then delivered into the cancellous bone or cavity 107 of the spinous process 101 and/or within the lamina 103. The material is selected to provide reinforcing properties to the spinous process 101 and/or lamina 103 sufficient to support (whether alone or in combination with other support elements) a spine support structure, a prosthesis, or other device attached to the spinous process and or supported lamina. The material may be a bone cement or polymer with strength and hardness properties selected to provide sufficient reinforcement to the region so that the spinous process may be used at least in part, to support an implant structure for attaching to and manipulating the biomechanics of the spine. Examples include but are not limited to polymers such as acrylic cement developed for use in vertebroplasty procedures. The material may be a flowable polymer material that cures within the cavity. Suitable materials may be readily selected by one of ordinary skill in the art.
  • [0071]
    Reinforcement structures may be placed within the cavity prior to, during or after injection of flowable material for further strength properties. As illustrated, an additional support structure 106 is provided within the cavity. The support structure 106 may be inserted through a cannula and released to expand as a spring-like or self-expanding member, into the cavity. The support structure 106 provides further support of the spinous process and/or lamina. Alternatively, or additionally, one or more posts or struts may be provided within the cavity or extending out of the spinous process or lamina from the area of cancellous bone, to supplement the support of the spinous process or lamina in combination with the polymer or other curable material. The reinforcement structures may be formed of a number of different materials such as, e.g., a metal or biocompatible polymer. Such reinforcement structures may also be used in other bony areas of the spine including the vertebra, the pedicles, facets, the transverse process, etc.
  • [0072]
    As shown in FIGS. 2A and 2B, an inferior portion 109 of a spinous process 108 may also be reinforced. Similarly a hole 110 is drilled in the inferior portion of the spinous process 108 and a cavity 111 is formed. The cavity 111 is similarly filled with a curable polymer and is reinforced by reinforcing elements 112 positioned within the cavity.
  • [0073]
    The reinforcement structure may be used in a number of applications including increasing the strength of healthy bone to support the load and fixation of orthopedic implants, as well as increasing the strength of bone weakened by osteoporosis, chronic steroid use, avascular necrosis, weakened by injury and cancer involving the bone. According to one aspect, the reinforcement structure comprises a material that provides sufficient strength including but not limited to suitable polymers, e.g. PEAK, titanium, steel and carbon fiber.
  • [0074]
    The stabilizing and/or distracting devices described herein may be formed of a material that provides sufficient column strength including but not limited to suitable polymers, e.g. PEAK, titanium, steel, and carbon fiber.
  • [0075]
    Referring to FIGS. 3A and 3B, an alternative support structure 120 is illustrated. The support structure 120 allows the anchoring of implants under physiologic loads on the spinous process 101 while shielding underlying bone from loads that would normally cause the bone to fracture. (The implants may alternatively or in addition be anchored or attached to the lamina 103, e.g., with addition of small screws, barbs or adhesive that engage with the lamina while avoiding injuring the spinal cord surrounded by the lamina.) The support structure 120 comprises a hood like element positioned over the posterior arch 100, i.e., the spinous process 101 and lamina 103 of a spine 90. The support structure 120 may be made of a moldable or malleable material (e.g. putty, formable ceramic, clay-like material, or a moldable polymer or malleable alloy or metal) that cures into or forms a solid, strong structure. Heat, light, catalysts, precursors, or local pressure and force, for example, may be used to make the hood moldable or firm. The support structure of filling material to support the spinous process may be constructed or formed of moldable composites that can cure into hard material such as, e.g., ground glass powder or glass fiber fillers mixed into an acrylic matrix and activated with light or other biophysical modalities. Other cements or other curable materials may be suitable as well. The support structure 120 further comprises openings 121 to guide drill bits and/or for the placement of screws, reinforcement posts, or other instruments or supplemental support structures. The guide may insure accurate positioning of the implant. The support structure 120 may be anchored on the posterior arch by mold bending or forming the structure about the anatomy. The support structure 120 may be anchored into the lamina or spinous process by anchoring elements, such as, e.g., screws or barbs. The support structure 120 may also be anchored via screws or posts. Alternatively, the support structure 120 could be a preformed implant with contours that fit the anatomy of the posterior arch 100 or that are malleable or moldable to the anatomy. Also, the support structure 20 may be anchored into the pedicles 122 with screws, into the underlying bone with barbs, screws, bone anchors, or adhesives, over the edges of structures with hooks, or may be constructed of a plurality of pieces that may be assembled into one piece around the bone. Wings 120 a of support structure may be placed over the lamina to spread the force of any device attached to the support structure 120
  • [0076]
    As illustrated in FIGS. 3A and 3B, a sensor 120 b is positioned on the support structure 120. The sensor 120 b may be embedded in the material. The sensor may sense stress on the support structure 120 from implants secured to it, or may sense other information that may be desirable to monitor. The sensor may include a communication element configured to communicate sensed information to an external device, e.g., when interrogated.
  • [0077]
    Referring to FIGS. 4A-4D, a support structure 130 is illustrated positioned over a posterior portion 132 of a spinous process 131 with wings 130 a over the lamina 103 including small screws 130 b into lamina 103. Wings 130 a may help spread the force from any devices attached or coupled to the support structure 130. Pedicle screws 135 are anchored into pedicles 136 and are further anchored into the spinous process 131 through screws 134 positioned through holes 133 in the support structure 130. As shown in FIG. 4C, the screw 134 includes a sensor 134 a that may be used to sense loads on the device. Use of such sensors is described further herein. The pedicle screw 135 includes a screw capture device 135 a for receiving a screw or rod of a spinous process screw or other rod. The capture device 135 a may be a polyaxial head of a pedicle screw it may include a hole, a threaded screw hole with a washer or cap. Cross bar 135 b is positioned across the spine between heads of pedicle screws 135 to prevent pedical screws from creeping laterally. A wedge shaped nut 134 d between the head 134 c of the screw 134 and the support structure. Another nut 134 b may be positioned between support structure 120 and pedicle screw, and secure against the support structure 120. These features may be used in a similar manner in the embodiments described herein.
  • [0078]
    FIG. 5 illustrates the spinous process screws 134 coupled to a spinous process 101 of a first vertebra 91 through a hood or support structure 130 in a manner similar to that described above with respect to FIGS. 4A-4D. The screws 134 extend bilaterally across the posterior of a second vertebra 92 and are anchored to capture elements 135 a of pedicle screws 135 anchored into pedicles 93 a of a third vertebra 93.
  • [0079]
    FIG. 6 illustrates a device for stabilizing or distracting the spine with pedicle screws 135 and cross bar 135 b positioned as in FIG. 4D. Hood structure 132 includes openings for receiving screws 132 b coupled to the hood 132 on one end and to the heads 135 a of pedicle screws 135 and on the other end. The screws 132 b do not penetrate the spinous process. Obliquely threaded nuts secure the screws 132 b against the hood 132.
  • [0080]
    The reinforcement or supporting devices described herein may be used in conjunction with a number of different spine devices, including, for example, the various distraction, fusing or dynamic stabilizing devices described herein. The hoods or reinforcement devices herein may also be customized, for example by using stereolithography. The hoods or reinforcement devices may be used for example with a brace. The pedicle screw may be telescoping as described with respect to FIGS. 22C and 22D.
  • [0081]
    The devices described herein may be coupled to the spinous process using minimally invasive techniques. These techniques may include percutaneously accessing the spinous process and/or using dilators to access the spinous process at an oblique angle with respect to median plane m and/or horizontal plane h through the spine of the patient.
  • [0082]
    FIG. 7A is a side view of a joint of the spine with a fixation device percutaneously implanted to fuse adjacent vertebrae by fixation of the facet joints. Pedicle screw 146 in the pedicle 143 of the adjacent vertebral members 141, 142. As illustrated in FIG. 7B, the pedicle screw 146 has a polyaxial screw head 147 for receiving a spinous process screw 148 having a tapered tip. The spinous process screw 148 is screwed from the contralateral side of the spinous process, through the spinous process 140 of vertebral member 141, adjacent the facet joint 149 between the vertebral member 141 and vertebral member 142, and then captured or placed into the head 147 of the pedicle screw 146.
  • [0083]
    When implanted, the pedicle screws are positioned in the pedicles in a generally known manner. The facet joint or facet joints between the spinal members that are to be fused, are debrided and grafted. A flank stab wound is made to expose the base of the spinous process. The spinous process screw is then inserted and navigated through the wound to the spinous process and/or soft tissue. Tissue dilators or retractors may be used to facilitate insertion of the spinous process screw through soft tissue. The spinous process screw 148 is then placed through the spinous process 140, and into and captured by the head 147 of the pedicle screw 146. Compression across and the facet joint 149 may be provided using a nut placet in the polyaxial head of the pedicle screw. Alternatively, external compression may be used prior to placement of the oblique rod of the spinous process screw. A similar screw may also be placed from the spinous process 140 to the contralateral pedicle. The spinous process 140 may be reinforced prior to or after placing the screw 148.
  • [0084]
    Referring to FIG. 8A, a similar fusion system as illustrated with respect to FIGS. 7A and 7B. Pedicle screw 156 is positioned in the pedicle 153 of the adjacent vertebral members 151, 152. The pedicle screw 156 has a polyaxial screw head 157 for receiving a spinous process screw 158 having a tapered tip. The spinous process screw 158 is screwed from the contralateral side of the spinous process 150, through the spinous process 150 of vertebral member 151, through the facet joint 159 between the vertebral member 151 and vertebral member 152 and then into the head 157 of the pedicle screw 156.
  • [0085]
    An oblique skin stab wound is made to navigate to the base of the spinous process 150, which may be exposed under direct vision. The spinous process screw 158 (or other device) is then placed through the spinous process 150, across (adjacent or through) the facet joint 159, and into the head 157 of the pedicle screw 156 (or otherwise attached to a pedicle attachment device for attaching devices to the pedicle), immobilizing the facet joint 159. A similar screw may also be placed from the spinous process 150 to the contralateral pedicle. The spinous process may be reinforced prior to or after placing the screw or other device. The other devices attached or coupled to the spinous process as described herein may be similarly deployed.
  • [0086]
    The devices described herein may be coupled to the spinous process using minimally invasive techniques. These techniques may include percutaneously accessing the spinous process and/or using dilators to access the spinous process at an oblique angle with respect to median plane and/or horizontal plane through the spine of the patient.
  • [0087]
    Referring to FIGS. 9A and 9B, a spine is illustrated with a spinal fusion system in place. A spinous process screw 168 is placed from the contralateral side of the spinous process 160, through the spinous process 160 of a first vertebra 161 and across the facet joint 169 between the first vertebra 161 and an adjacent second vertebra 162, and into the pedicle 164 of the second vertebra 162.
  • [0088]
    Another feature of the spinous process screw of FIGS. 9A-9B is that it may be configured to exert flexible, stabilizing, nonfusion forces to the motion segment. For example, this may be used in the event that patient suffers from pain due to laxity or other dysfunction of the spinal structures (e.g. degenerative spondylolisthesis). In other words, the looseness or other dysfunction of the joint and surrounding tissue may cause pain. The present invention provides a device and method for dynamically stabilizing (or reducing) such a joint while allowing some flexibility and movement. The device and method provide such stabilization on an oblique angle with respect to the rotational axis of the spine, i.e. at an oblique angle with respect to the median and horizontal planes of the spine. The spinous process and a pedicle could also be used to anchor a device exerting a stabilizing or compression or contractile force between the two anchors on an oblique angle. Devices that may be used to exert such a contractile force may include, for example, polymeric materials, super elastic metals, and fabrics. The spinous process screw 168 includes a sensor 165 a that may be used to sense motion of the distraction device. The forces or stresses on the device may be monitored and used to determine if it is necessary to convert the device to a fusion type device or to otherwise reduce or alter motion. The sensor may also be used as a diagnostic device to measure the amount of joint motion upon insertion of the implant or over time.
  • [0089]
    The system illustrated in FIGS. 9A and 9B may also be used for the treatment of spondylolysis, to attain stability across the pars interarticularis.
  • [0090]
    The spinous processes 140, 150, 160 may be reinforced in a manner as described herein. The various rods or screws through the spinous processes 140, 150, 160 may also be positioned through a posterior arch reinforcing member as described herein.
  • [0091]
    FIG. 10 illustrates a spinous process rod or screw 60 in accordance with the invention. The spinous process rod or screw 60 comprises an elongate portion 61 configured to extend through the reinforcement hood 51 (for example, as described in further detail herein with reference to FIGS. 3A-4D positioned around spinous process 50 and into an adjacent element such as, e.g. a pedicle screw. The spinous process rod or screw 60 may include threaded portions. The distal end 62 of the rod may be threaded or otherwise configured to engage an adjacent element. The spinous process screw or rod 60 further comprises a proximal securing element 65 located on the proximal portion 64 of the spinous process screw or rod 60. The proximal securing element 65 is configured to engage a first wall 52 portion of the spinous process 60 or reinforcement hood 51. (“Engage” as used herein means to either directly or indirectly engage.) As illustrated, the distal securing element 63 comprises an obliquely threaded nut that is configured to receive screw 61 which is coupled to the hood 51 at an oblique angle with respect to the wall 53. The oblique threaded nut may be used in other applications where a screw is oblique with respect to the abject to which is engaged, coupled or attached. The obliquely threaded nut may have a predetermined angle at which it directs the screw with respect to the hood to guide the desired angle or directions of the screw placement. This may be predetermined base on imaging of a particular patient's anatomy. A distal securing element 63 is provided more distal of the proximal securing element 65. The distal securing element is configured to engage a second wall portion 53 generally opposite the first wall portion 52 so that the spinous process element is secured or fixed to the hood and spinous process. (The term “fix” as used herein means either directly or indirectly fix to and may include dynamic elements.)
  • [0092]
    FIG. 11 illustrates a spinous process rod or screw 80 in accordance with the invention. The spinous process rod or screw 80 comprises an elongate portion 81 configured to extend through the reinforcement hood 71 (for example, as described in further detail herein with reference to FIGS. 3A-4D) positioned around spinous process 70 and into an adjacent element such as, e.g. a pedicle screw. The spinous process rod or screw 80 may include threaded portions. The distal end 82 of the rod may be threaded or otherwise configured to engage an adjacent element, e.g. with a connecting member, including but not limited to connecting members described herein. The spinous process screw or rod 80 further comprises a proximal securing element 85 located on the proximal portion 84 of the spinous process screw or rod 80. The proximal securing element 85 is configured to engage a first wall 72 portion of the spinous process 70 or reinforcement hood 71. (“Engage” as is used herein to mean either directly or indirectly engage.) A hollow space or chamber 74 is formed in the reinforcement hood 71 so that the hollow chamber may engageably receive one or more securing elements, e.g. first and second securing elements 86, 87 therein. The securing elements 86, 87 may be positioned on either or both sides of the spinous process 70 through which the screw or rod 80 is positioned. As illustrated in FIG. 11, securing element 86 is positioned on the proximal portion 84 of the screw 80 while securing portion 87 is positioned on the distal portion 82 of the screw 80. Securing elements 86, 87 may be obliquely threaded nuts, for example, as described with respect to nut 80 b in FIG. 3E. Securing elements may be attached a variety of ways, for example as illustrated in FIGS. 12A-12B and 13A-13B. FIGS. 12A-12B illustrate manual insertion of securing elements in accordance with the invention. Spinous process screw 80 a is placed through both wings of the hood 71 while passing through holes 1000 as shown. Securing elements 86 a and 87 a are inserted into receiving holes 1001 within the hood 71 and receiving holes 1002 within the spinous process screw 80 a. Securing elements 86 a, 87 a prevent movement of the spinous process screw 80 a. FIGS. 13A-13B illustrate automatic deployment of securing elements in accordance with the invention. The securing elements 86 b and 87 b could be positioned in recesses 1004 in the spinous process screw 80 b and spring loaded with springs 1003 attached inside of the recesses 1004. An external sheath 1005 is positioned around the spinous process screw 80 b. The screw 80 b is positioned through a spinous process and a hood. The securing elements are then deployed upon removal of an external sheath 1005. The securing element 86,86 a, or 86 b is configured to engage the first wall portion of the spinous process (or hood) from within the hood 71. The securing element 87, 87 a, or 87 b is configured to engage a second wall portion 73 generally opposite the first wall portion 72 so that the spinous process element is secured to the hood and spinous process.
  • [0093]
    FIGS. 14A and 14B illustrate a spinous process rod or screw 54 in accordance with the invention. The spinous process rod or screw 54 comprises an elongate outer tube portion 55 and an inner rod portion 56. The inner rod portion 56 is configured to move longitudinally within the tube portion 55 to lengthen or shorten the spinous process screw or rod 54. The inner wall of the tube portion 55 may include a threaded inner wall that mates with a threaded outer wall of the rod 54 so that the rod may be screwed to advance the rod 56 and thereby lengthen or shorten the spinous process screw or rod 54. Once the outer rod 55 and screw 56 are positioned within a spinous process or hood 51 the spinous process screw or rod 54 may then be lengthened as shown in FIG. 14B to extend through the reinforcement hood 51. The lengthened spinous process screw may be used to distract the spinal segment or segments as well.
  • [0094]
    The pedicle attachment devices herein may include a sensor that may be used to sensor one or more parameters e.g., strain, pressure, motion, position change, that provides information about possible screw failure. The sensor may communicate the information to an external device, e.g. telemetrically, and may be passively powered by an external device.
  • [0095]
    According to another aspect of the invention a rod is provided that is anchored to with pedicle screws with screw heads made of or attached to swivel collars, polyaxial heads, or other movable fasteners to allow for near physiologic levels of motion of the spinal motion segment. Angular movement may be provided where a distracting element attaches on either side of a motion segment so that when distracting or lengthening the device, there is accommodation in the device for the change of angle that occurs.
  • [0096]
    FIG. 15 illustrates an enlarged portion of a spinal prosthesis. The prosthesis 280 may provide support of the load on the spine where a facet has been removed or may provide other support or distraction. The prosthesis 280 comprises a distraction bar 281 used to distract a motion segment of the spine in a number of manners including the distraction devices described herein. A pedicle screw 283 is screwed into a pedicle of the spine or other anatomical location. The distraction bar 281 includes and articulating cup 282 having an inner surface 282 a. The pedicle screw 283 has a ball 284 received by and coupled to the cup 282 of the distraction bar 281. In addition to shock absorbing capabilities described in various embodiments herein, the distraction bar 281 also articulates with a portion of the spine to which the pedicle screw 283 is attached.
  • [0097]
    FIG. 16 illustrates a variation of the prosthesis 280 described with respect to FIG. 15. The prosthesis 285 comprises a distraction bar 286 and an articulating ball 287 configured to engage and couple with an articulation cup 289 of a pedicle screw 288. The prosthesis 285 operates in a similar manner as prosthesis 280.
  • [0098]
    FIG. 17 illustrates a variation of the prostheses 280, 285 described herein respectively with respect to FIGS. 15 and 16. The prosthesis 290 comprises a distraction bar 291 having an end 292 with a lumen 293 for slidably receiving the end 296 of a pedicle screw 295. The end 296 of the pedicle screw 295 comprises a ball portion 297 attached to a neck 298. The ball 297 portion is configured to slide within the lumen 293 of the distraction bar 291 which contains the ball portion 297. The neck 298 of the pedicle screw 295 extends out of the distraction bar 291 through a longitudinal slit 294 that slidably receives the narrower neck portion 298 of the pedicle screw 295.
  • [0099]
    One embodiment of the invention is a rod anchored at each end across a motion segment that can be “switched” between dynamic stabilization and rigid fixation in a minimally invasive, percutaneous, or non-invasive fashion. One way for this to occur is injection of a flowable material within the lumen of the device, which would cure, and immobilize the components which allow for motion. Electrical current, heat, mechanical energy, or other techniques could also be used to render movable components fixed. Another method is insertion of a rigid implant axially along the length of the dynamic implant. This method of rendering a flexible prosthesis rigid may be applied to the design of other combination motion/fixation prostheses, including disc, facet hip, knee, fingers shoulder, elbows, and ankle prostheses, etc.
  • [0100]
    FIGS. 18-21 illustrate convertible or adjustable dynamic stabilization devices for joints. The stiffness or flexibility of the device may be altered or titrated after implantation to adapt the stiffness to a particular patient, and/or to adjust the stiffness over time, for example when laxity of the joint increases with age. Referring to FIG. 18 illustrates a dynamic stabilization prosthesis 350. The prosthesis comprises a flexible coil 352 contained in a tube member 351 comprising telescoping tubes. The prosthesis 350 may be used in a number of manners affixed across a joint motion segment to dynamically stabilize the joint. The coil 352 may be energy absorbing. The coil 352 may also be configured to exert a distracting force on the joint when implanted. FIG. 19 illustrates the dynamic stabilization prosthesis 350 of FIG. 18 converted to a rigid or more rigid prosthesis. The prosthesis 350 includes a slit 353 for receiving a rigid wire member 354. In FIG. 19 the rigid wire member 354 is inserted into the slit 353 to form the prosthesis from a dynamic prosthesis into a rigid prosthesis. As an alternative to a rigid wire member, a flexible coil of a selected stiffness may be inserted to change the stiffness of the dynamic prosthesis. The tube may alternatively comprise a ferromagnetic material contained therein and an electromagnetic field is applied that causes the prosthesis to become stiffer. The field may be varied to provide a variety of gradients in stiffness. The device may also include a sensor that operates as sensor 170 a described herein. Feedback may be provided and the stiffness of the prosthesis adjusted accordingly. The stiffness may be varied when implanted using patient feedback so that the implant is more or less flexible depending upon an individual patient's needs. In addition the stiffness may be changed at different times during the course of the implants lifetime. For example, the stiffness may be increased when an increased amount of stabilization is required.
  • [0101]
    FIG. 20 illustrates an alternative prosthesis 360 also comprising a flexible coil 362 contained in a tube member 361. The tube member is configured to receive a fluid material such as a curable polymer 364 that cures in the tubular member to create a rigid prosthesis. As illustrated in FIG. 20 a rigid prosthesis is formed from a dynamic prosthesis by injecting the polymer material 364 into the tubular member 361. The flexibility/stiffness properties of the prosthesis may be selected by selecting such properties of the polymer to be injected.
  • [0102]
    As illustrated in FIG. 21 a flexible prosthesis 365 is illustrated. The flexibility of the prosthesis 365 is adjustable by injecting a polymer material into one or more of the columnar cavities 367, 368, 369. The polymer may be injected into each cavity at a different time so the stiffness of the prosthesis may be increased gradually over time. The stiffness/flexibility properties of the polymer injected may also be selected according to a desired stiffness/flexibility of the implant.
  • [0103]
    According to an embodiment of the invention, the dynamic stabilizer may comprise a shock absorber that has both energy absorbing and energy dissipating properties. The tension band effect of the posterior columns may also offload the pressures borne by anterior column of the spine. So in addition to helping to protect the facet joints, other aspects of the invention would help slow the progression of degenerative disc disease, annular degradation, disc herniation, and vertebral compression fractures.
  • [0104]
    Another aspect of the invention is to supplement implants or repair procedures of the anterior column with a posterior shock absorber device (rod, screw, plate). Examples of these implants or procedures include total disc replacements, annular repair, artificial nucleus, and vertebroplasty/kyphoplasty.
  • [0105]
    Another aspect of the invention is to supplement implants or repair procedures of the posterior column with a shock absorber rod. Examples of these implants or procedures include interspinous distraction wedges, facet joint replacements, and posterior arch replacements.
  • [0106]
    Another aspect of the invention provides a posterior support implants with shock absorbing properties, to decrease or remove the load experienced by the facets. Implant components may include springs, coils, hydraulic or fluid filled piston chambers, or elastic materials. Each end of the device could be anchored in such a fashion so the rod bridges the facet joint, reducing the loads borne by the joint. This is believed to reduce wear of the facets and resulting pain and altered spinal biomechanics.
  • [0107]
    An improved device is provided that utilizes the spinous process, the pedicle, adjacent ribs and/or a transverse process or a combination including one or more of these anatomical structures, to correct or stabilize a deformed spine. The device may be used to correct scoliosis using one or more of these anatomical structures and multiple points at a plurality of spine segments. The correction may be made incrementally over time and may or may not include a fusion process.
  • [0108]
    In one embodiment, a percutaneously and obliquely placed rigid or dynamic stabilizer is provided. Stabilizer segments are anchored to base of spinous process at one end and a pedicle screw at the other end, as a unilateral temporary stabilizer. The dynamic stabilizers described herein may be adjusted over time to gradually bring the spine in alignment. The stabilizer may be used to derotate (untorque) and correct the spine. A stabilizer placed across a motion segment, i.e., not at the same vertebral level may be used to create overgrowth where desired, i.e. on the non-instrumented side of the motion segment. Such overgrowth may help stabilization or correction of the spine.
  • [0109]
    FIGS. 22A-24 illustrate an explantable, temporary scoliosis stabilization device. The system is configured to be manipulable once it is installed. The systems illustrated are configured to alter the orientation of a vertebral body and in particular to untorque the spine about the axis of the spinal column as well as applying a corrective straightening or translation force with respect to a vertical rod. According to one aspect of the invention, a device for correcting deformities of the spine is provided where the device may be adjusted over time to direct the corrective forces as needed over time. According to another aspect, a multipoint stabilizing device is coupled to the posterior portions of the spine.
  • [0110]
    The systems illustrated in FIGS. 22A-24 comprise a multipoint anchoring mechanism that provides for multidimensional correction of the spinal or spinal segments by positioning the anchor at a plurality of locations on a spine. As illustrated for example in FIGS. 22A-22H, the multiple locations include the spinous process and pedicle of a particular vertebra. A bar is attached between the spinous process and pedicle. A force directing device couples the bar to a vertical rod. As illustrated in FIGS. 23A-23B, the multiple locations include the spinous process of one level and the pedicle of another level (e.g. an adjacent level). As illustrated in FIG. 24, the multiple locations include the spinous process, through a transverse process 605 into a costal aspect of a rib 606. The vertical rod in these figures is attached or coupled to the spine at neutral and balanced vertebra, typically only at the most upper and most lower positions.
  • [0111]
    The device comprises a telescoping rod (or plate) 536 to which various segments of the spinal column are to be fixed. The rod 536 telescopes to adjust the height to accommodate particular segments or a height of the spine. As illustrated in FIG. 22A a portion 500 of the spine comprises a plurality of adjacent segments 501, 502, 503, 504, 505, (additional adjacent segments may also be corrected). The portion 500 of the spine exhibits a concave curvature between segments 501 and 505. Pedicle screws 506, 507, 508, 509, 510 are attached to pedicles of segments 50, 502, 503, 504, 505, respectively. Dynamic stabilizers 516, 517, 518, 519, 520 are attached to pedicle screws 506, 507, 508, 509, 510 and to spinous processes 521, 522, 523, 524, 525 respectively of segments 501, 502, 503, 504, 505. Wires 526, 527, 528, 529, 530 attached to the rod 536 via hooks 531, 532, 533, 534, 535 attached to the rod 536. The wires 526, 527, 528, 529, 530 are used to tension the portion of the spine 500 to pull on the concavity. If the portion has a convexity, rods may be used in place of wires to push on the convexity to straighten the spine.
  • [0112]
    FIG. 22B is a cross section of FIG. 22A along the lines 22B-22B. The pedicle screw 508 includes a screw capture device 508 a for receiving a screw head or rod of a dynamic stabilizer, in this case, a spinous process screw 518. The capture device may be a hole, a threaded screw hole with a washer or cap. The pedicle screw 508 may be configured to telescope outwards or inwards to be positioned to receive the screw head or rod of a dynamic stabilizer 518 as shown in FIGS. 22C and 22D. The spinous process screw 518 is shown in 22C where, given the trajectory of the spinous process screw 518, its end does not intercept the capture device 508 a of the pedicle screw 508. As shown in FIG. 22D the pedicle screw's trunk 508 b is lengthened with a telescoping or other similar lengthening mechanism so that the end of the spinous process screw 518 may be positioned in the capture device 508 a.
  • [0113]
    The spinous process screw 518 is anchored through the reinforced spinous process 523 (having a reinforcement hood 523 a or is otherwise reinforced as described herein. Note that the reinforcement hood may have a single lamina wing where a single screw is attached as opposed to bilateral screws.) with a head portion 518 a engaging the pedicle screw 503 and a rod portion 518 b extending through a reinforced spinous process 523. The dynamic stabilizer 518 includes a loop connector end 518 c for receiving a hook 518 d of a wire (or a telescoping rod) 528 that is attached to the rod 536 with a ratcheted connector 533. The wire may also be a rod, spring, elastic band or other force-directing device. The loop connector end 518 c may also be a poly axial connector that allows translation in a variety of directions or places, i.e., so that an oblique angle rod can be captured. (for example, similar to pedicle screw 503 and capture device 503 a) The wire 528 may be adjusted or tightened at various times with the ratcheted connector 533, e.g., during a period of time where the spine is being corrected. As the spine is straightened, excess wire may be trimmed off. This procedure may be done percutaneously, e.g. by accessing wire near the skin. Each dynamic stabilizer is similarly constructed.
  • [0114]
    FIGS. 22E-22H illustrate various dynamic stabilizers that may be used to correct spinal deformity. Dynamic stabilizers 518 e, 518 i, and 518 m are coupled by coupling mechanisms 541 a-c to the telescoping rod 536. The coupling mechanisms 541 a-c may be positioned on or through the plate or telescoping rod 536. Dynamic stabilizer 518 e includes rod 518 f that will extend through a reinforced spinous process and is coupled by a coupling mechanism 518 g to rod 518 h in an end-to-end fashion. Rod 518 h slidably extends through opening in coupling mechanism 541 a attached to the telescoping rod 536. The rod 518 h is adjustable within the coupling mechanism 541 a to lengthen or shorten the distance of the dynamic stabilizer 518 e between the spinous process and the telescoping rod 536. The coupling mechanism 541 a is configured to clamp down on the rod 518 h to secure it in place once the distance has been adjusted. The coupling mechanisms 541 a-c may include a screw, cam or clamp mechanism to clamp or lockably engage rods 518 h, l, and p as described in use herein.
  • [0115]
    Similarly, dynamic stabilizer 518 i includes rod 518 j that will extend through a reinforced spinous process and is coupled by a coupling mechanism 518 k to rod 518 l in an end to side fashion. Rod 518 l slidably extends through opening in coupling mechanism 541 b attached to the telescoping rod 536. The rod 518 l is adjustable within the coupling mechanism 541 b to lengthen or shorten the distance of the dynamic stabilizer 518 i between the spinous process and the telescoping rod 536. The coupling mechanism 541 b is configured to clamp down on the rod 518 l to secure it in place once the distance has been adjusted.
  • [0116]
    Dynamic stabilizer 518 m includes a rod 518 n that will extend through a reinforced spinous process and is coupled by a threaded coupling 518 o to rod 518 p. The rod 518 p is slidably and rotatably positioned within a cylindrical hole in coupling mechanism 541 c attached to the telescoping rod 536. The rod 518 p may be rotated, i.e., screwed or unscrewed so that the stabilizer lengthens or shortens at the threaded coupling 518 o. The rotation or screwing may be actuated at or near the skin where the rod 518 p is positioned in the coupling mechanism 541 c.
  • [0117]
    Dynamic stabilizer 518 q includes a rod 518 r that will extend through a reinforced spinous process and is coupled by a multiaxial coupling 518 s similar to a multiaxial screw head type coupling, to rod 518 t. The rod 518 t is a telescoping rod and is coupled by coupling mechani8sm 541 d to the vertical rod 536.
  • [0118]
    Each of the dynamic stabilizers may include sensors located thereon to sense data corresponding to a parameter of the dynamic stabilization device or the spine. FIG. 22E-22H illustrate sensors 542 a-542 d located on the dynamic stabilizer. The sensors may comprise, e.g., a strain, stress, pressure, position or motion sensor. Such sensors may include a variety of sensors that are generally know. For example, strain gauges, accelerometers or piezo electric sensors may be employed to sense parameters that correspond, e.g., to the position of the spine, a vertebra, a dynamic stabilizer, as well as the parameters relating to the forces or mechanical loads that are effecting the device. Each of the sensors may individually sense information or information relative to each of the other sensors may be sensed and compared. The information may be used to set tension on the device, to identify when repositioning is necessary or to otherwise provide information as to the status of the device or portions thereof, or status of the spine that is being treated. The sensors may include some level or circuitry including, e.g. a telemetry circuit that transmits information concerning the sensors to an external device. The sensors may be battery powered or may use passive circuits that are powered by an external device. The information may be used to identify when one of the stabilizers no longer has tension associated with the stabilizer thus identifying when the tension needs to be modified in the device. Accordingly, each segment may be moved separately, monitored separately and adjusted separately form the other segments. Each segment may be moved to a different degree and in different directions or at different angles with varying forces.
  • [0119]
    FIG. 23A illustrates an alternative configuration of the correction device according to the invention. A portion 550 of the spine comprises a plurality of adjacent segments 551, 552, 553, 554, 555, 555 a (additional adjacent segments may also be corrected). The portion 550 of the spine exhibits a concave curvature between segments 551 and 555 a. Pedicle screws 556, 557, 558, 559, 560 are attached to pedicles of segments 551, 552, 553, 554, 555, respectively. Dynamic stabilizers 566, 567, 568, 569, 570 are attached to pedicle screws 556, 557, 558, 559, 560 and through spinous processes, 572, 573, 574, 575, 576 respectively of adjacent segments 555 a, 551, 552, 553, 554. Thus, the dynamic stabilizers are positioned across the motion segments between the corresponding adjacent segments. The dynamic stabilizers 566, 567, 568, 569,570 attached to the telescoping rod 576 in one or more manners such as, for example, the dynamic stabilizers 518, 518 e, 518 i, 518 m, 518 q as illustrated in FIGS. 22A-22H, herein. The dynamic stabilizers 566, 567, 568, 569, 570 are used to tension the portion of the spine 500 to pull on the concavity, or if the portion has a convexity, to push , pull on, or translate the convexity to straighten the spine. Thus each of the dynamic stabilizers are attached a plurality of locations on the spine and operate to stabilize adjacent segments with respect to each other.
  • [0120]
    FIG. 23B illustrates a pedicle screw and dynamic stabilizer in greater detail. The pedicle screw 558 is screwed into pedicle 563 of vertebra 553. The pedicle screw 558 includes a screw hole 558 a for receiving a screw head or rod of a dynamic stabilizer 568. A screw capture device 568 b such as a nut or a threaded portion of the pedicle screw is configured to capture and receive the dynamic stabilizer screw or rod portion 568 a. The capture device 568 b of the stabilizer engages the pedicle screw 558 and a rod portion 568 b extends through a reinforced spinous process 574. The dynamic stabilizer 568 includes a connector end 580 for receiving a wire 578 or a hook of a telescoping rod that is attached to the telescoping rod 576. The dynamic stabilizer 568 is anchored through the reinforced spinous process 574 of an adjacent vertebra 554 (FIG. 17A) thus immobilizing or stabilizing the motion segment between the vertebra 553, 554. This device may also be used in fusion, i.e. to fuse the motion segments across vertebra of a multipoint connector. The device may also be used to encourage overgrowth at certain locations. In particular it may encourage overgrowth on the non-fused lateral side of a vertebra (opposing the fused lateral side) stabilized with the multipoint connector between two vertebrae.
  • [0121]
    FIG. 24 illustrates a device for treating a deformity such as scoliosis. The device includes a dynamic stabilizer 600 comprising a spinous process screw 601 and a pedicle screw 602 including a spinous process screw capture device 603. The spinous process screw is configured to be positioned through a reinforced spinous process 604 and through a transverse process 605 into a costal aspect of a rib 606. The dynamic stabilizer 600 includes a connector portion 607 configured to be connected to a telescoping rod as described herein with reference to FIGS. 22A-H and 23A-23B. Similar to FIGS. 22A-H and 23A-23B, a plurality of segments may be secured to a telescoping rod with a plurality of dynamic stabilizers. The pedicle screw in this and all other embodiments described in this application may include a telescoping portion that can adjust the length of the screw head from the anchoring point where the pedicle screw is anchored into the bone. The pedicle screw 602 also includes a sensor 608 located thereon (or incorporated therewith). The sensor may comprise, for example, a motion detector, a position detector, a pressure sensor, a strain gauge, and ultrasonic transducer/sensor. The sensor may sense a change in strain on the screw that may be due to loosening or repositioning of the screw. The sensor may also sense a change in position of the screw that indicates a change in alignment and corresponding loosening or repositioning of the screw. The sensor may also sense a change in pressure due to loosening or repositioning of the screw. The sensor may also include an ultrasonic transducer and transmitter that can determine change in positioning of the screw, e.g. loosening of the screw indicated by a change in interfaces of materials or characteristic property change indicating screw loosening or repositioning. The sensor may include some electronics such as a telemetry circuit that allows it to communicate with an external device. The sensor may also be powered by an external device e.g., in a manner generally known in the art.
  • [0122]
    The various embodiments of the invention described herein may include sensors integrated with or provided on a structural spinal implant. A number of factors may be detected as described herein. Additional factors may include, e.g., local inflammation, pressure, tension, edema, motion, water content, and electrolytes or other chemicals. The sensors allow a doctor to monitor patients for response to healing, or may be used by the doctor to guide serial adjustments to the patient's treatment. For example, measurements from the sensing means could lead the doctor to change the length or tension of a distraction rod or stabilization device. Patients could adjust therapy based on measurements from the sensing device, or could be alerted to notify their doctor should certain measurements be of concern. The sensor is configured to be adjustable to sensed stresses. The sensor may for example, be a strain gauge, a pressure sensor accelerometer, position sensor, imaging device, etc. The sensor may be used in the initial adjustment of the prosthesis or may be monitored over time. The sensor may sense shear/torsion tension/compression. Sensors may sense stresses at various motion segments. The sensor may be used to compare stresses at various motion segments or locations. Various sensors may be selected from sensors that are known to one of skill in the art or that are commercially available.
  • [0000]
    Anchoring of Therapeutic Devices
  • [0123]
    Some patients obtain back pain relief with injections of steroids and anesthetic agents at the site of pain; however the relief is temporary requiring that patients return for repeat injections when their pain recurs.
  • [0124]
    One embodiment of the invention comprises an anchor device with a therapeutic substance or drug delivery device, e.g. a drug port and/or reservoir, or matrix attached to a vertebra. In one embodiment, the device is anchored adjacent a site near where pain is present. The port is configured to deliver steroids or anesthetic agents via a catheter to a desired location, for example, the facet joint, neural foramen, vertebral body, annulus, nucleus, back muscles, back ligaments, bone metastases, intrathecal space, epidural space, or other targets in, on, or around the spine. The catheter can direct the drug to the correct location by positioning the end of the catheter at a target location. The port is configured to be refilled periodically percutaneously, e.g. using an imaging device and a percutaneously placed needle that can inject the refill into the port, e.g. through a biocompatible polymer or rubber type port access mechanism. The device further comprises a patient actuation mechanism for patient control of drug delivery as needed for pain relief, manually or remotely using a telemetrically triggered delivery from an external telemetry control device. According one aspect of the invention such a device is attached to a boney structure of the spine. Other device that may be attached to the spine may include sensory or therapeutic devices, including nerve stimulators, bone growth stimulators and radioactive seeds.
  • [0125]
    In addition, a structural implant could be anchored to bone, to which a sensory or therapeutic device could be attached. The sensory or therapeutic device could be placed external to the bone, on the surface of the bone, or internal to the bone.
  • [0126]
    FIGS. 25 and 26 illustrate drug delivery devices 370, 380, respectively, in accordance with the invention. The drug delivery device 370 includes a reservoir 375 attached by an anchor 371 configured to anchor the reservoir 375 to the bone of the spine. In particular, in this embodiment, the anchor 371 comprises a pedicle screw that anchors the device to the pedicle 373 of a vertebra 372. The reservoir 375 includes a catheter 376 in communication with the contents of the reservoir 375 and having an end positioned adjacent or in a zygapophyseal joint 378 where the drug is directed to have a therapeutic effect on the joint 378. The device may include a telemetrically actuable pump mechanism for delivering the drug to the joint upon telemetric actuation by an external control device. The device 370 further comprises a port 377 for receiving (e.g. via a percutaneously introduced needle) into the reservoir 375, refills of the therapeutic substance or drug. Device 380 comprises a similar catheter 386, and reservoir 385 attached by an anchor 381 to the spinous process 383 or alternatively an adjacent lamina 384. The spinous process 383 or lamina 384 may be reinforced prior to attachment of the anchor 381 or may be attached to a reinforcement device positioned at the posterior arch of the spine, as described herein with reference to FIGS. 1A-7B.
Citations de brevets
Brevet cité Date de dépôt Date de publication Déposant Titre
US3242922 *25 juin 196329 mars 1966Charles B ThomasInternal spinal fixation means
US3648691 *24 févr. 197014 mars 1972Univ Colorado State Res FoundMethod of applying vertebral appliance
US4024588 *3 oct. 197524 mai 1977Allo Pro A.G.Artificial joints with magnetic attraction or repulsion
US4078559 *26 mai 197614 mars 1978Erkki Einari NissinenStraightening and supporting device for the spinal column in the surgical treatment of scoliotic diseases
US4269178 *4 juin 197926 mai 1981Keene James SHook assembly for engaging a spinal column
US4369769 *13 juin 198025 janv. 1983Edwards Charles CSpinal fixation device and method
US4448191 *7 juil. 198115 mai 1984Rodnyansky Lazar IImplantable correctant of a spinal curvature and a method for treatment of a spinal curvature
US4573454 *17 mai 19844 mars 1986Hoffman Gregory ASpinal fixation apparatus
US4611582 *27 déc. 198316 sept. 1986Wisconsin Alumni Research FoundationVertebral clamp
US4773402 *19 août 198727 sept. 1988Isola Implants, Inc.Dorsal transacral surgical implant
US4805602 *3 nov. 198621 févr. 1989Danninger Medical TechnologyTranspedicular screw and rod system
US5000166 *12 avr. 198919 mars 1991Sulzer Brothers LimitedImplant kit for stabilizing regions of a spine
US5011484 *10 oct. 198930 avr. 1991Breard Francis HSurgical implant for restricting the relative movement of vertebrae
US5030220 *29 mars 19909 juil. 1991Advanced Spine Fixation Systems IncorporatedSpine fixation system
US5084049 *8 févr. 198928 janv. 1992Acromed CorporationTransverse connector for spinal column corrective devices
US5092867 *11 juil. 19893 mars 1992Harms JuergenCorrection and supporting apparatus, in particular for the spinal column
US5133716 *7 nov. 199028 juil. 1992Codespi CorporationDevice for correction of spinal deformities
US5176679 *23 sept. 19915 janv. 1993Lin Chih IVertebral locking and retrieving system
US5196014 *4 août 199223 mars 1993Lin Chih IVertebral locking and retrieving system
US5219349 *15 févr. 199115 juin 1993Howmedica, Inc.Spinal fixator reduction frame
US5242443 *15 août 19917 sept. 1993Smith & Nephew Dyonics, Inc.Percutaneous fixation of vertebrae
US5306275 *31 déc. 199226 avr. 1994Bryan Donald WLumbar spine fixation apparatus and method
US5330474 *29 juil. 199319 juil. 1994Lin Chih IVertebral locking and retrieving system
US5382248 *10 sept. 199217 janv. 1995H. D. Medical, Inc.System and method for stabilizing bone segments
US5387212 *26 janv. 19937 févr. 1995Yuan; Hansen A.Vertebral locking and retrieving system with central locking rod
US5387213 *20 août 19937 févr. 1995Safir S.A.R.L.Osseous surgical implant particularly for an intervertebral stabilizer
US5397363 *11 août 199214 mars 1995Gelbard; Steven D.Spinal stabilization implant system
US5413576 *10 févr. 19939 mai 1995Rivard; Charles-HilaireApparatus for treating spinal disorder
US5437669 *12 août 19931 août 1995Amei Technologies Inc.Spinal fixation systems with bifurcated connectors
US5437671 *7 mars 19941 août 1995Zimmer, Inc.Perpendicular rod connector for spinal fixation device
US5480440 *7 juil. 19932 janv. 1996Smith & Nephew Richards, Inc.Open surgical technique for vertebral fixation with subcutaneous fixators positioned between the skin and the lumbar fascia of a patient
US5490851 *2 août 199413 févr. 1996Nenov; Nikolay N.Method and apparatus for treatment of idiopathic scoliosis
US5496318 *18 août 19935 mars 1996Advanced Spine Fixation Systems, Inc.Interspinous segmental spine fixation device
US5498262 *25 avr. 199412 mars 1996Bryan; Donald W.Spinal fixation apparatus and method
US5540689 *21 mars 199430 juil. 1996Sanders; Albert E.Apparatus for securing a rod adjacent to a bone
US5549679 *1 mars 199527 août 1996Kuslich; Stephen D.Expandable fabric implant for stabilizing the spinal motion segment
US5591165 *15 oct. 19937 janv. 1997Sofamor, S.N.C.Apparatus and method for spinal fixation and correction of spinal deformities
US5649926 *6 juin 199522 juil. 1997Advanced Spine Fixation Systems, Inc.Spinal segmental reduction derotational fixation system
US5704936 *9 avr. 19936 janv. 1998EurosurgicalSpinal osteosynthesis device
US5725582 *18 août 199310 mars 1998Surgicraft LimitedSurgical implants
US5728097 *9 juil. 199617 mars 1998Sdgi Holding, Inc.Method for subcutaneous suprafascial internal fixation
US5733284 *15 juil. 199431 mars 1998Paulette FairantDevice for anchoring spinal instrumentation on a vertebra
US5782831 *6 nov. 199621 juil. 1998Sdgi Holdings, Inc.Method an device for spinal deformity reduction using a cable and a cable tensioning system
US5814046 *12 nov. 199329 sept. 1998Sofamor S.N.C.Pedicular screw and posterior spinal instrumentation
US5928232 *4 avr. 199627 juil. 1999Advanced Spine Fixation Systems, IncorporatedSpinal fixation system
US5938663 *5 mars 199617 août 1999Stryker France, S.A.Spinal instruments, particularly for a rod
US6015409 *10 oct. 199718 janv. 2000Sdgi Holdings, Inc.Apparatus and method for spinal fixation and correction of spinal deformities
US6086590 *2 févr. 199911 juil. 2000Pioneer Laboratories, Inc.Cable connector for orthopaedic rod
US6176861 *12 févr. 199723 janv. 2001Sdgi Holdings, Inc.Modular spinal system
US6277120 *20 sept. 200021 août 2001Kevin Jon LawsonCable-anchor system for spinal fixation
US6293949 *1 mars 200025 sept. 2001Sdgi Holdings, Inc.Superelastic spinal stabilization system and method
US6358254 *11 sept. 200019 mars 2002D. Greg AndersonMethod and implant for expanding a spinal canal
US6364883 *23 févr. 20012 avr. 2002Albert N. SantilliSpinous process clamp for spinal fusion and method of operation
US6391030 *15 déc. 199821 mai 2002Spinal Concepts, Inc.Surgical cable system and method
US6423065 *24 avr. 200123 juil. 2002Bret A. FerreeCross-coupled vertebral stabilizers including cam-operated cable connectors
US6451019 *26 mai 200017 sept. 2002St. Francis Medical Technologies, Inc.Supplemental spine fixation device and method
US6514255 *25 févr. 20004 févr. 2003Bret FerreeSublaminar spinal fixation apparatus
US6537276 *1 mai 200125 mars 2003Stryker Trauma GmbhApparatus for bracing vertebrae
US6551320 *5 juil. 200122 avr. 2003The Cleveland Clinic FoundationMethod and apparatus for correcting spinal deformity
US6554831 *1 sept. 200029 avr. 2003Hopital Sainte-JustineMobile dynamic system for treating spinal disorder
US6565605 *13 déc. 200020 mai 2003Medicinelodge, Inc.Multiple facet joint replacement
US6579319 *29 nov. 200017 juin 2003Medicinelodge, Inc.Facet joint replacement
US6589243 *8 mars 19998 juil. 2003Guy ViartPosterior backbone osteosynthesis device
US6610091 *20 oct. 200026 août 2003Archus Orthopedics Inc.Facet arthroplasty devices and methods
US6682533 *23 juil. 199927 janv. 2004Spinal Concepts, Inc.Surgical cable system and method
US6709435 *28 mars 200223 mars 2004A-Spine Holding Group Corp.Three-hooked device for fixing spinal column
US6773437 *28 sept. 200110 août 2004Sdgi Holdings, Inc.Shape memory alloy staple
US6986771 *23 mai 200317 janv. 2006Globus Medical, Inc.Spine stabilization system
US7018379 *4 mars 200428 mars 2006Sdgi Holdings, Inc.Flexible spinal stabilization system and method
US7029475 *30 avr. 200418 avr. 2006Yale UniversitySpinal stabilization method
US7048736 *17 mai 200223 mai 2006Sdgi Holdings, Inc.Device for fixation of spinous processes
US7074237 *22 avr. 200311 juil. 2006Facet Solutions, Inc.Multiple facet joint replacement
US7087056 *2 avr. 20048 août 2006Vaughan Medical Technologies, Inc.Vertebral stabilization assembly and method
US7220262 *15 mars 200222 mai 2007Sdgi Holdings, Inc.Spinal fixation system and related methods
US7335203 *9 févr. 200426 févr. 2008Kyphon Inc.System and method for immobilizing adjacent spinous processes
US7338490 *21 mai 20034 mars 2008Warsaw Orthopedic, Inc.Reduction cable and bone anchor
US7367978 *20 août 20026 mai 2008Warsaw Orthopedic, Inc.Adjustable spinal tether
US7481828 *22 juil. 200327 janv. 2009Abbott Spine, Inc.Vertebral fixing system
US7524324 *3 déc. 200428 avr. 2009Kyphon SarlSystem and method for an interspinous process implant as a supplement to a spine stabilization implant
US20020055739 *5 juil. 20019 mai 2002The Cleveland Clinic FoundationMethod and apparatus for correcting spinal deformity
US20020133155 *21 mai 200219 sept. 2002Ferree Bret A.Cross-coupled vertebral stabilizers incorporating spinal motion restriction
US20030040746 *19 juil. 200227 févr. 2003Mitchell Margaret E.Spinal stabilization system and method
US20030109881 *31 juil. 200212 juin 2003Showa Ika Kohgyo Co., Ltd.Implant for bone connector
US20030153915 *6 févr. 200314 août 2003Showa Ika Kohgyo Co., Ltd.Vertebral body distance retainer
US20040097931 *14 oct. 200320 mai 2004Steve MitchellInterspinous process and sacrum implant and method
US20040106921 *25 août 20033 juin 2004Cheung Kenneth McDevice for correcting spinal deformities
US20040167520 *1 mars 200426 août 2004St. Francis Medical Technologies, Inc.Spinous process implant with tethers
US20050033295 *8 août 200310 févr. 2005Paul WisnewskiImplants formed of shape memory polymeric material for spinal fixation
US20050043797 *19 juil. 200424 févr. 2005Lee Casey K.Facet joint prosthesis
US20050049705 *29 août 20033 mars 2005Hale Horace WinstonFacet implant
US20050055096 *20 mai 200410 mars 2005Depuy Spine, Inc.Functional spinal unit prosthetic
US20050080420 *20 août 200414 avr. 2005Farris Robert A.Multi-axial orthopedic device and system
US20050149030 *19 déc. 20037 juil. 2005Depuy Spine, Inc.Facet joint fixation system
US20050154390 *5 nov. 200414 juil. 2005Lutz BiedermannStabilization device for bones comprising a spring element and manufacturing method for said spring element
US20060009767 *30 juin 200512 janv. 2006Kiester P DExpandable rod system to treat scoliosis and method of using the same
US20060047282 *30 août 20052 mars 2006Vermillion Technologies, LlcImplant for correction of spinal deformity
US20060064091 *28 sept. 200523 mars 2006Depuy Spine, Inc.Rod attachment for head to head cross connector
US20060084996 *6 déc. 200520 avr. 2006Stryker Trauma GmbhApparatus for bracing vertebrae
US20070073293 *14 avr. 200629 mars 2007Martz Erik OSystem and method for flexible correction of bony motion segment
Référencé par
Brevet citant Date de dépôt Date de publication Déposant Titre
US74589819 mars 20052 déc. 2008The Board Of Trustees Of The Leland Stanford Junior UniversitySpinal implant and method for restricting spinal flexion
US764852311 févr. 200519 janv. 2010Interventional Spine, Inc.Method and apparatus for spinal stabilization
US776691514 sept. 20063 août 2010Jackson Roger PDynamic fixation assemblies with inner core and outer coil-like member
US781564829 sept. 200819 oct. 2010Facet Solutions, IncSurgical measurement systems and methods
US782442918 juil. 20032 nov. 2010Interventional Spine, Inc.Method and apparatus for spinal fixation
US784618528 avr. 20067 déc. 2010Warsaw Orthopedic, Inc.Expandable interspinous process implant and method of installing same
US785783220 juil. 200528 déc. 2010Interventional Spine, Inc.Method and apparatus for spinal stabilization
US78625879 janv. 20064 janv. 2011Jackson Roger PDynamic stabilization assemblies, tool set and method
US79014378 janv. 20088 mars 2011Jackson Roger PDynamic stabilization member with molded connection
US79014388 déc. 20058 mars 2011Interventional Spine, Inc.Method and apparatus for spinal stabilization
US791456029 sept. 200829 mars 2011Gmedelaware 2 LlcSpinal facet implant with spherical implant apposition surface and bone bed and methods of use
US7918887 *29 mars 20065 avr. 2011Roche Martin WBody parameter detecting sensor and method for detecting body parameters
US792737512 sept. 200819 avr. 2011Doty Keith LDynamic six-degrees-of-freedom intervertebral spinal disc prosthesis
US79429001 août 200717 mai 2011Spartek Medical, Inc.Shaped horizontal rod for dynamic stabilization and motion preservation spinal implantation system and method
US795117030 mai 200831 mai 2011Jackson Roger PDynamic stabilization connecting member with pre-tensioned solid core
US795535730 juin 20057 juin 2011Ellipse Technologies, Inc.Expandable rod system to treat scoliosis and method of using the same
US796397830 mai 200821 juin 2011Spartek Medical, Inc.Method for implanting a deflection rod system and customizing the deflection rod system for a particular patient need for dynamic stabilization and motion preservation spinal implantation system
US798102528 oct. 200819 juil. 2011Ellipse Technologies, Inc.Adjustable implant and method of use
US798524330 mai 200826 juil. 2011Spartek Medical, Inc.Deflection rod system with mount for a dynamic stabilization and motion preservation spinal implantation system and method
US799326917 févr. 20069 août 2011Medtronic, Inc.Sensor and method for spinal monitoring
US799337230 mai 20089 août 2011Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system with a shielded deflection rod system and method
US799337715 janv. 20079 août 2011Interventional Spine, Inc.Method and apparatus for spinal fixation
US79981766 juin 200816 août 2011Interventional Spine, Inc.Method and apparatus for spinal stabilization
US799817729 sept. 200816 août 2011Gmedelaware 2 LlcLinked bilateral spinal facet implants and methods of use
US799817829 sept. 200816 août 2011Gmedelaware 2 LlcLinked bilateral spinal facet implants and methods of use
US80028001 août 200723 août 2011Spartek Medical, Inc.Horizontal rod with a mounting platform for a dynamic stabilization and motion preservation spinal implantation system and method
US800280330 mai 200823 août 2011Spartek Medical, Inc.Deflection rod system for a spine implant including an inner rod and an outer shell and method
US800751824 sept. 200930 août 2011Spartek Medical, Inc.Load-sharing component having a deflectable post and method for dynamic stabilization of the spine
US80121751 août 20076 sept. 2011Spartek Medical, Inc.Multi-directional deflection profile for a dynamic stabilization and motion preservation spinal implantation system and method
US801217719 juin 20096 sept. 2011Jackson Roger PDynamic stabilization assembly with frusto-conical connection
US801218124 sept. 20096 sept. 2011Spartek Medical, Inc.Modular in-line deflection rod and bone anchor system and method for dynamic stabilization of the spine
US801685917 févr. 200613 sept. 2011Medtronic, Inc.Dynamic treatment system and method of use
US801686124 sept. 200913 sept. 2011Spartek Medical, Inc.Versatile polyaxial connector assembly and method for dynamic stabilization of the spine
US802139624 sept. 200920 sept. 2011Spartek Medical, Inc.Configurable dynamic spinal rod and method for dynamic stabilization of the spine
US802954113 juil. 20074 oct. 2011Simpirica Spine, Inc.Methods and systems for laterally stabilized constraint of spinous processes
US804333711 juin 200725 oct. 2011Spartek Medical, Inc.Implant system and method to treat degenerative disorders of the spine
US804811330 mai 20081 nov. 2011Spartek Medical, Inc.Deflection rod system with a non-linear deflection to load characteristic for a dynamic stabilization and motion preservation spinal implantation system and method
US804811524 sept. 20091 nov. 2011Spartek Medical, Inc.Surgical tool and method for implantation of a dynamic bone anchor
US804811828 avr. 20061 nov. 2011Warsaw Orthopedic, Inc.Adjustable interspinous process brace
US804812130 mai 20081 nov. 2011Spartek Medical, Inc.Spine implant with a defelction rod system anchored to a bone anchor and method
US804812230 mai 20081 nov. 2011Spartek Medical, Inc.Spine implant with a dual deflection rod system including a deflection limiting sheild associated with a bone screw and method
US804812330 mai 20081 nov. 2011Spartek Medical, Inc.Spine implant with a deflection rod system and connecting linkages and method
US804812524 sept. 20091 nov. 2011Spartek Medical, Inc.Versatile offset polyaxial connector and method for dynamic stabilization of the spine
US80481281 août 20071 nov. 2011Spartek Medical, Inc.Revision system and method for a dynamic stabilization and motion preservation spinal implantation system and method
US80527211 août 20078 nov. 2011Spartek Medical, Inc.Multi-dimensional horizontal rod for a dynamic stabilization and motion preservation spinal implantation system and method
US805272230 mai 20088 nov. 2011Spartek Medical, Inc.Dual deflection rod system for a dynamic stabilization and motion preservation spinal implantation system and method
US805747215 mai 200815 nov. 2011Ellipse Technologies, Inc.Skeletal manipulation method
US805751430 mai 200815 nov. 2011Spartek Medical, Inc.Deflection rod system dimensioned for deflection to a load characteristic for dynamic stabilization and motion preservation spinal implantation system and method
US805751524 sept. 200915 nov. 2011Spartek Medical, Inc.Load-sharing anchor having a deflectable post and centering spring and method for dynamic stabilization of the spine
US805751724 sept. 200915 nov. 2011Spartek Medical, Inc.Load-sharing component having a deflectable post and centering spring and method for dynamic stabilization of the spine
US80667396 déc. 200729 nov. 2011Jackson Roger PTool system for dynamic spinal implants
US80667471 août 200729 nov. 2011Spartek Medical, Inc.Implantation method for a dynamic stabilization and motion preservation spinal implantation system and method
US80707741 août 20076 déc. 2011Spartek Medical, Inc.Reinforced bone anchor for a dynamic stabilization and motion preservation spinal implantation system and method
US807077530 mai 20086 déc. 2011Spartek Medical, Inc.Deflection rod system for a dynamic stabilization and motion preservation spinal implantation system and method
US807077630 mai 20086 déc. 2011Spartek Medical, Inc.Deflection rod system for use with a vertebral fusion implant for dynamic stabilization and motion preservation spinal implantation system and method
US80707801 août 20076 déc. 2011Spartek Medical, Inc.Bone anchor with a yoke-shaped anchor head for a dynamic stabilization and motion preservation spinal implantation system and method
US80800391 août 200720 déc. 2011Spartek Medical, Inc.Anchor system for a spine implantation system that can move about three axes
US808377224 sept. 200927 déc. 2011Spartek Medical, Inc.Dynamic spinal rod assembly and method for dynamic stabilization of the spine
US808377524 sept. 200927 déc. 2011Spartek Medical, Inc.Load-sharing bone anchor having a natural center of rotation and method for dynamic stabilization of the spine
US809250015 sept. 200910 janv. 2012Jackson Roger PDynamic stabilization connecting member with floating core, compression spacer and over-mold
US809250124 sept. 200910 janv. 2012Spartek Medical, Inc.Dynamic spinal rod and method for dynamic stabilization of the spine
US80925025 oct. 200710 janv. 2012Jackson Roger PPolyaxial bone screw with uploaded threaded shank and method of assembly and use
US809702424 sept. 200917 janv. 2012Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post and method for stabilization of the spine
US81009154 sept. 200924 janv. 2012Jackson Roger POrthopedic implant rod reduction tool set and method
US81053561 août 200731 janv. 2012Spartek Medical, Inc.Bone anchor with a curved mounting element for a dynamic stabilization and motion preservation spinal implantation system and method
US810535728 avr. 200631 janv. 2012Warsaw Orthopedic, Inc.Interspinous process brace
US810535930 mai 200831 janv. 2012Spartek Medical, Inc.Deflection rod system for a dynamic stabilization and motion preservation spinal implantation system and method
US810536016 juil. 200931 janv. 2012Orthonex LLCDevice for dynamic stabilization of the spine
US81053632 févr. 200931 janv. 2012The Board Of Trustees Of The Leland Stanford Junior UniversitySpinal implant and method for restricting spinal flexion
US81053681 août 200731 janv. 2012Jackson Roger PDynamic stabilization connecting member with slitted core and outer sleeve
US810997030 mai 20087 févr. 2012Spartek Medical, Inc.Deflection rod system with a deflection contouring shield for a spine implant and method
US810997715 janv. 20077 févr. 2012Interventional Spine, Inc.Method and apparatus for spinal fixation
US811413030 mai 200814 févr. 2012Spartek Medical, Inc.Deflection rod system for spine implant with end connectors and method
US811413424 sept. 200914 févr. 2012Spartek Medical, Inc.Spinal prosthesis having a three bar linkage for motion preservation and dynamic stabilization of the spine
US81141588 juil. 200814 févr. 2012Kspine, Inc.Facet device and method
US81188421 août 200721 févr. 2012Spartek Medical, Inc.Multi-level dynamic stabilization and motion preservation spinal implantation system and method
US812375220 janv. 201028 févr. 2012Spartek Medical. Inc.Systems and methods for injecting bone filler into the spine
US812673623 janv. 200928 févr. 2012Warsaw Orthopedic, Inc.Methods and systems for diagnosing, treating, or tracking spinal disorders
US81424801 août 200727 mars 2012Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system with horizontal deflection rod and articulating vertical rods
US81475201 août 20073 avr. 2012Spartek Medical, Inc.Horizontally loaded dynamic stabilization and motion preservation spinal implantation system and method
US815281023 nov. 200410 avr. 2012Jackson Roger PSpinal fixation tool set and method
US816294822 juil. 200824 avr. 2012Jackson Roger POrthopedic implant rod reduction tool set and method
US81629795 juin 200824 avr. 2012K Spine, Inc.Medical device and method to correct deformity
US816298217 avr. 200924 avr. 2012Simpirica Spine, Inc.Methods and systems for constraint of multiple spine segments
US81629871 août 200724 avr. 2012Spartek Medical, Inc.Modular spine treatment kit for dynamic stabilization and motion preservation of the spine
US81728811 août 20078 mai 2012Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system and method with a deflection rod mounted in close proximity to a mounting rod
US817288211 juin 20078 mai 2012Spartek Medical, Inc.Implant system and method to treat degenerative disorders of the spine
US81778151 août 200715 mai 2012Spartek Medical, Inc.Super-elastic deflection rod for a dynamic stabilization and motion preservation spinal implantation system and method
US81825151 août 200722 mai 2012Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system and method
US81825161 août 200722 mai 2012Spartek Medical, Inc.Rod capture mechanism for dynamic stabilization and motion preservation spinal implantation system and method
US81873055 juin 200929 mai 2012Simpirica Spine, Inc.Methods and apparatus for deploying spinous process constraints
US818730717 avr. 200929 mai 2012Simpirica Spine, Inc.Structures and methods for constraining spinal processes with single connector
US81924691 août 20075 juin 2012Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system and method with a deflection rod
US819749023 févr. 200912 juin 2012Ellipse Technologies, Inc.Non-invasive adjustable distraction system
US820229919 mars 200819 juin 2012Collabcom II, LLCInterspinous implant, tools and methods of implanting
US82023228 mars 201119 juin 2012Doty Keith LDynamic six-degrees-of-freedom intervertebral spinal disc prosthesis
US820641829 août 200826 juin 2012Gmedelaware 2 LlcSystem and method for facet joint replacement with detachable coupler
US821114729 août 20083 juil. 2012Gmedelaware 2 LlcSystem and method for facet joint replacement
US82111501 août 20073 juil. 2012Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system and method
US821115524 sept. 20093 juil. 2012Spartek Medical, Inc.Load-sharing bone anchor having a durable compliant member and method for dynamic stabilization of the spine
US821627531 oct. 200810 juil. 2012The Board Of Trustees Of The Leland Stanford Junior UniversitySpinal implant and method for restricting spinal flexion
US82162812 déc. 200910 juil. 2012Spartek Medical, Inc.Low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod
US822672418 juin 200924 juil. 2012Doty Keith LIntervertebral spinal disc prosthesis
US82413302 nov. 200714 août 2012Lanx, Inc.Spinous process implants and associated methods
US825202729 août 200828 août 2012Gmedelaware 2 LlcSystem and method for facet joint replacement
US825203128 avr. 200628 août 2012Warsaw Orthopedic, Inc.Molding device for an expandable interspinous process implant
US82573972 déc. 20104 sept. 2012Spartek Medical, Inc.Low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod
US826797924 sept. 200918 sept. 2012Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post and axial spring and method for dynamic stabilization of the spine
US827308929 sept. 200625 sept. 2012Jackson Roger PSpinal fixation tool set and method
US827750510 juin 20112 oct. 2012Doty Keith LDevices for providing up to six-degrees of motion having kinematically-linked components and methods of use
US828267125 oct. 20109 oct. 2012OrthonexSmart device for non-invasive skeletal adjustment
US82875985 déc. 201116 oct. 2012TrueMotion Spine, Inc.True spinal motion preserving, shock absorbing, intervertebral spinal disc prosthesis
US829289213 mai 200923 oct. 2012Jackson Roger POrthopedic implant rod reduction tool set and method
US829292617 août 200723 oct. 2012Jackson Roger PDynamic stabilization connecting member with elastic core and outer sleeve
US829826730 mai 200830 oct. 2012Spartek Medical, Inc.Spine implant with a deflection rod system including a deflection limiting shield associated with a bone screw and method
US83087715 juin 200913 nov. 2012Simpirica Spine, Inc.Methods and apparatus for locking a band
US831783610 nov. 200927 nov. 2012Spartek Medical, Inc.Bone anchor for receiving a rod for stabilization and motion preservation spinal implantation system and method
US833379224 sept. 200918 déc. 2012Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post and method for dynamic stabilization of the spine
US833753624 sept. 200925 déc. 2012Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post with a compliant ring and method for stabilization of the spine
US83431929 avr. 20091 janv. 2013Ellipse Technologies, Inc.Expandable rod system to treat scoliosis and method of using the same
US834897828 avr. 20068 janv. 2013Warsaw Orthopedic, Inc.Interosteotic implant
US835393220 août 200815 janv. 2013Jackson Roger PPolyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US835718226 mars 200922 janv. 2013Kspine, Inc.Alignment system with longitudinal support features
US835718326 mars 200922 janv. 2013Kspine, Inc.Semi-constrained anchoring system
US83667451 juil. 20095 févr. 2013Jackson Roger PDynamic stabilization assembly having pre-compressed spacers with differential displacements
US837212229 avr. 201112 févr. 2013Spartek Medical, Inc.Low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod
US8372147 *27 janv. 201112 févr. 2013Martin W. RocheMethod for detecting body parameters
US8372153 *27 janv. 201112 févr. 2013Martin W. RocheMethod for detecting body parameters
US837693728 janv. 201019 févr. 2013Warsaw Orhtopedic, Inc.Tissue monitoring surgical retractor system
US837706724 janv. 201219 févr. 2013Roger P. JacksonOrthopedic implant rod reduction tool set and method
US83770733 janv. 200919 févr. 2013Ray WasielewskiMethod of designing orthopedic implants using in vivo data
US838275610 nov. 200926 févr. 2013Ellipse Technologies, Inc.External adjustment device for distraction device
US839412727 juin 201212 mars 2013Spartek Medical, Inc.Low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod
US839413323 juil. 201012 mars 2013Roger P. JacksonDynamic fixation assemblies with inner core and outer coil-like member
US840396118 avr. 200826 mars 2013Simpirica Spine, Inc.Methods and devices for controlled flexion restriction of spinal segments
US84039648 août 201126 mars 2013Simpirica Spine, Inc.Methods and systems for increasing the bending stiffness and constraining the spreading of a spinal segment
US841973420 oct. 201116 avr. 2013Ellipse Technologies, Inc.Skeletal manipulation method
US842561126 oct. 201023 avr. 2013Warsaw Orthopedic, Inc.Expandable orthopedic implant system and method
US84309167 févr. 201230 avr. 2013Spartek Medical, Inc.Spinal rod connectors, methods of use, and spinal prosthesis incorporating spinal rod connectors
US844465427 janv. 201121 mai 2013Martin W. RocheMethod for detecting body parameters
US844468113 avr. 201221 mai 2013Roger P. JacksonPolyaxial bone anchor with pop-on shank, friction fit retainer and winged insert
US84495433 sept. 201028 mai 2013Ellipse Technologies, Inc.Bone growth device and method
US844955628 janv. 201128 mai 2013Martin W. RocheMethod for detecting body parameters
US84546609 août 20114 juin 2013Simpirica Spine, Inc.Methods and systems for laterally stabilized constraint of spinous processes
US84754983 janv. 20082 juil. 2013Roger P. JacksonDynamic stabilization connecting member with cord connection
US848611029 déc. 201116 juil. 2013The Board Of Trustees Of The Leland Stanford Junior UniversitySpinal implant and method for restricting spinal flexion
US85065995 août 201113 août 2013Roger P. JacksonDynamic stabilization assembly with frusto-conical connection
US851808527 janv. 201127 août 2013Spartek Medical, Inc.Adaptive spinal rod and methods for stabilization of the spine
US851808617 juin 201027 août 2013K Spine, Inc.Semi-constrained anchoring system
US852390413 juil. 20073 sept. 2013The Board Of Trustees Of The Leland Stanford Junior UniversityMethods and systems for constraint of spinous processes with attachment
US852960610 mars 201010 sept. 2013Simpirica Spine, Inc.Surgical tether apparatus and methods of use
US85407535 oct. 200424 sept. 2013Roger P. JacksonPolyaxial bone screw with uploaded threaded shank and method of assembly and use
US854553826 avr. 20101 oct. 2013M. Samy AbdouDevices and methods for inter-vertebral orthopedic device placement
US85569385 oct. 201015 oct. 2013Roger P. JacksonPolyaxial bone anchor with non-pivotable retainer and pop-on shank, some with friction fit
US856265310 mars 201022 oct. 2013Simpirica Spine, Inc.Surgical tether apparatus and methods of use
US856845110 nov. 200929 oct. 2013Spartek Medical, Inc.Bone anchor for receiving a rod for stabilization and motion preservation spinal implantation system and method
US859151526 août 200926 nov. 2013Roger P. JacksonSpinal fixation tool set and method
US85915602 août 201226 nov. 2013Roger P. JacksonDynamic stabilization connecting member with elastic core and outer sleeve
US861376014 déc. 201124 déc. 2013Roger P. JacksonDynamic stabilization connecting member with slitted core and outer sleeve
US864172328 mai 20114 févr. 2014Orthonex LLCSkeletal adjustment device
US866871930 mars 201011 mars 2014Simpirica Spine, Inc.Methods and apparatus for improving shear loading capacity of a spinal segment
US868509323 janv. 20091 avr. 2014Warsaw Orthopedic, Inc.Methods and systems for diagnosing, treating, or tracking spinal disorders
US869671130 juil. 201215 avr. 2014Roger P. JacksonPolyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US870275929 août 200822 avr. 2014Gmedelaware 2 LlcSystem and method for bone anchorage
US871515910 juin 20116 mai 2014Ellipse Technologies, Inc.Adjustable implant and method of use
US871528210 févr. 20126 mai 2014Ellipse Technologies, Inc.System and method for altering rotational alignment of bone sections
US87152844 févr. 20056 mai 2014Interventional Spine, Inc.Method and apparatus for bone fixation with secondary compression
US872156612 nov. 201013 mai 2014Robert A. ConnorSpinal motion measurement device
US872168818 mai 201213 mai 2014Collabcom II, LLCInterspinous implant, tools and methods of implanting
US877799429 sept. 200815 juil. 2014Gmedelaware 2 LlcSystem and method for multiple level facet joint arthroplasty and fusion
US878449017 mai 201122 juil. 2014Ray C. WasielewskiMethod of designing orthopedic implants using in vivo data
US879037222 mars 201229 juil. 2014Simpirica Spine, Inc.Methods and systems for constraint of multiple spine segments
US880816311 oct. 201219 août 2014Ellipse Technologies, Inc.Adjustable implant and method of use
US88149133 sept. 201326 août 2014Roger P JacksonHelical guide and advancement flange with break-off extensions
US88280581 sept. 20109 sept. 2014Kspine, Inc.Growth directed vertebral fixation system with distractible connector(s) and apical control
US884064610 mai 200723 sept. 2014Warsaw Orthopedic, Inc.Spinous process implants and methods
US884564913 mai 200930 sept. 2014Roger P. JacksonSpinal fixation tool set and method for rod reduction and fastener insertion
US885218710 févr. 20127 oct. 2014Ellipse Technologies, Inc.Variable length device and method
US885223630 nov. 20127 oct. 2014Ellipse Technologies, Inc.Expandable rod system to treat scoliosis and method of using the same
US885223917 févr. 20147 oct. 2014Roger P JacksonSagittal angle screw with integral shank and receiver
US887092829 avr. 201328 oct. 2014Roger P. JacksonHelical guide and advancement flange with radially loaded lip
US889465728 nov. 201125 nov. 2014Roger P. JacksonTool system for dynamic spinal implants
US890027228 janv. 20132 déc. 2014Roger P JacksonDynamic fixation assemblies with inner core and outer coil-like member
US890606329 sept. 20089 déc. 2014Gmedelaware 2 LlcSpinal facet joint implant
US891147721 oct. 200816 déc. 2014Roger P. JacksonDynamic stabilization member with end plate support and cable core extension
US891147821 nov. 201316 déc. 2014Roger P. JacksonSplay control closure for open bone anchor
US891586618 janv. 200823 déc. 2014Warsaw Orthopedic, Inc.Implantable sensor and associated methods
US892047218 avr. 201330 déc. 2014Kspine, Inc.Spinal correction and secondary stabilization
US892667015 mars 20136 janv. 2015Roger P. JacksonPolyaxial bone screw assembly
US892667221 nov. 20136 janv. 2015Roger P. JacksonSplay control closure for open bone anchor
US893662315 mars 201320 janv. 2015Roger P. JacksonPolyaxial bone screw assembly
US894519022 déc. 20113 févr. 2015Interventional Spine, Inc.Method and apparatus for spinal fixation
US897446322 mai 201210 mars 2015Ellipse Technologies, Inc.Non-invasive adjustable distraction system
US897449630 août 200710 mars 2015Jeffrey Chun WangInterspinous implant, tools and methods of implanting
US89799047 sept. 201217 mars 2015Roger P JacksonConnecting member with tensioned cord, low profile rigid sleeve and spacer with torsion control
US899895919 oct. 20117 avr. 2015Roger P JacksonPolyaxial bone anchors with pop-on shank, fully constrained friction fit retainer and lock and release insert
US899896017 mai 20137 avr. 2015Roger P. JacksonPolyaxial bone screw with helically wound capture connection
US899896828 nov. 20127 avr. 2015Choice Spine, LpFacet screw system
US90114919 janv. 201221 avr. 2015K Spine, Inc.Facet device and method
US901149921 janv. 201521 avr. 2015Ellipse Technologies, IncExpandable rod system to treat scoliosis and method of using the same
US9039772 *9 déc. 200926 mai 2015Industry Foundation Of Chonnam National UniversityImage-based patient-specific medical spinal surgery method and spinal prosthesis
US905013915 mars 20139 juin 2015Roger P. JacksonOrthopedic implant rod reduction tool set and method
US905014429 août 20089 juin 2015Gmedelaware 2 LlcSystem and method for implant anchorage with anti-rotation features
US90559782 oct. 201216 juin 2015Roger P. JacksonOrthopedic implant rod reduction tool set and method
US905598125 janv. 200816 juin 2015Lanx, Inc.Spinal implants and methods
US90787116 juin 201214 juil. 2015Ellipse Technologies, Inc.Devices and methods for detection of slippage of magnetic coupling in implantable medical devices
US909538416 oct. 20084 août 2015Aro Medical Aps U/StiftelseMethods, systems and apparatuses for torsional stabilization
US910140426 janv. 201111 août 2015Roger P. JacksonDynamic stabilization connecting member with molded connection
US910758010 nov. 201018 août 2015Universite Pierre Et Marie Curie (Paris 6)Device for measuring the activity of the spinal cord of a vertebra
US910770611 sept. 201318 août 2015Simpirica Spine, Inc.Surgical tether apparatus and methods of use
US911395910 sept. 201425 août 2015K2M, Inc.Spinal correction and secondary stabilization
US914444412 mai 201129 sept. 2015Roger P JacksonPolyaxial bone anchor with helical capture connection, insert and dual locking assembly
US91493042 août 20136 oct. 2015The Board Of Trustees Of The Leland Sanford Junior UniversityMethods and systems for constraint of spinous processes with attachment
US916807115 sept. 200927 oct. 2015K2M, Inc.Growth modulation system
US917368120 déc. 20123 nov. 2015K2M, Inc.Alignment system with longitudinal support features
US917996023 févr. 201510 nov. 2015Ellipse Technologies, Inc.Skeletal manipulation method
US921115023 sept. 201015 déc. 2015Roger P. JacksonSpinal fixation tool set and method
US921603919 nov. 201022 déc. 2015Roger P. JacksonDynamic spinal stabilization assemblies, tool set and method
US92160418 févr. 201222 déc. 2015Roger P. JacksonSpinal connecting members with tensioned cords and rigid sleeves for engaging compression inserts
US922675825 févr. 20115 janv. 2016Decima Spine, Inc.Method and apparatus for spinal stabilization
US924796831 mars 20102 févr. 2016Lanx, Inc.Spinous process implants and associated methods
US924804329 juin 20112 févr. 2016Ellipse Technologies, Inc.External adjustment device for distraction device
US927178122 mars 20131 mars 2016Ellipse Technologies, Inc.Skeletal manipulation method
US927185725 mars 20151 mars 2016Ellipse Technologies, Inc.Adjustable implant and method of use
US92954998 mai 201329 mars 2016Empirical Spine, Inc.Methods and systems for laterally stabilized constraint of spinous processes
US93330091 juin 201210 mai 2016K2M, Inc.Spinal correction system actuators
US935804420 déc. 20127 juin 2016K2M, Inc.Semi-constrained anchoring system
US93580481 déc. 20117 juin 2016Facet-Link Inc.Fusion implant for facet joints
US936433111 janv. 201314 juin 2016Ray WasielewskiMethod of designing orthopedic implants using in vivo data
US939304514 mars 201419 juil. 2016Biomet Manufacturing, Llc.Clamping assembly for external fixation system
US93930477 sept. 201219 juil. 2016Roger P. JacksonPolyaxial bone anchor with pop-on shank and friction fit retainer with low profile edge lock
US93931172 janv. 201419 juil. 2016Nuvasive Specialized Orthopedics, Inc.System and method for altering rotational alignment of bone sections
US939311924 mars 201519 juil. 2016Nuvasive Specialized Orthopedics, Inc.Variable length device and method
US93989251 juil. 201426 juil. 2016Nuvasive Specialized Orthopedics, Inc.Expandable rod system to treat scoliosis and method of using the same
US940863829 janv. 20169 août 2016K2M, Inc.Spinal correction system actuators
US940864817 mars 20149 août 2016Interventional Spine, Inc.Method and apparatus for bone fixation with secondary compression
US941486331 juil. 201216 août 2016Roger P. JacksonPolyaxial bone screw with spherical capture, compression insert and alignment and retention structures
US943968310 mars 201513 sept. 2016Roger P JacksonDynamic stabilization member with molded connection
US944582612 janv. 201020 sept. 2016Decima Spine, Inc.Method and apparatus for spinal stabilization
US945191913 mai 201427 sept. 2016Orthosensor Inc.Method for detecting body parameters
US94519898 sept. 201127 sept. 2016Roger P JacksonDynamic stabilization members with elastic and inelastic sections
US94519937 janv. 201527 sept. 2016Roger P. JacksonBi-radial pop-on cervical bone anchor
US945199718 mars 201527 sept. 2016K2M, Inc.Facet device and method
US946304514 mars 201411 oct. 2016Biomet Manufacturing, LlcPolyaxial pivot housing for external fixation system
US946846821 nov. 201118 oct. 2016K2M, Inc.Transverse connector for spinal stabilization system
US946846917 sept. 201318 oct. 2016K2M, Inc.Transverse coupler adjuster spinal correction systems and methods
US946847117 sept. 201318 oct. 2016K2M, Inc.Transverse coupler adjuster spinal correction systems and methods
US948051710 oct. 20121 nov. 2016Roger P. JacksonPolyaxial bone anchor with pop-on shank, shank, friction fit retainer, winged insert and low profile edge lock
US950449617 mai 201329 nov. 2016Roger P. JacksonPolyaxial bone anchor with pop-on shank, friction fit retainer and winged insert
US95108658 sept. 20146 déc. 2016K2M, Inc.Growth directed vertebral fixation system with distractible connector(s) and apical control
US952202131 mars 201520 déc. 2016Roger P. JacksonPolyaxial bone anchor with retainer with notch for mono-axial motion
US952202818 sept. 201320 déc. 2016Interventional Spine, Inc.Method and apparatus for sacroiliac joint fixation
US95220707 mars 201320 déc. 2016Interventional Spine, Inc.Intervertebral implant
US952665010 juil. 201427 déc. 2016Nuvasive Specialized Orthopedics, Inc.Adjustable implant and method of use
US953281530 sept. 20133 janv. 2017Roger P. JacksonSpinal fixation tool set and method
US956609222 oct. 201414 févr. 2017Roger P. JacksonCervical bone anchor with collet retainer and outer locking sleeve
US957332221 juil. 201421 févr. 2017Ray C. WasielewskiMethod of designing orthopedic implants using in vivo data
US95971194 juin 201521 mars 2017Roger P. JacksonPolyaxial bone anchor with polymer sleeve
US962966929 juin 201225 avr. 2017Roger P. JacksonSpinal fixation tool set and method
US96361518 juin 20152 mai 2017Roger P JacksonOrthopedic implant rod reduction tool set and method
US96621432 déc. 201430 mai 2017Roger P JacksonDynamic fixation assemblies with inner core and outer coil-like member
US966215112 juin 201530 mai 2017Roger P JacksonOrthopedic implant rod reduction tool set and method
US96687713 févr. 20146 juin 2017Roger P JacksonSoft stabilization assemblies with off-set connector
US969381312 oct. 20154 juil. 2017Nuvasive Specialized Orthopedics, Inc.Skeletal manipulation method
US971348618 déc. 201425 juil. 2017DePuy Synthes Products, Inc.Method and apparatus for spinal fixation
US971753323 déc. 20141 août 2017Roger P. JacksonBone anchor closure pivot-splay control flange form guide and advancement structure
US97175341 oct. 20151 août 2017Roger P. JacksonPolyaxial bone anchor with pop-on shank and friction fit retainer with low profile edge lock
US971754113 avr. 20151 août 2017DePuy Synthes Products, Inc.Lamina implants and methods for spinal decompression
US972413628 déc. 20158 août 2017Zimmer Biomet Spine, Inc.Spinous process implants and associated methods
US973061211 juin 201515 août 2017Nuvasive Specialized Orthopedics, Inc.Devices and methods for detection of slippage of magnetic coupling in implantable medical devices
US974395710 sept. 201329 août 2017Roger P. JacksonPolyaxial bone screw with shank articulation pressure insert and method
US974396011 janv. 201629 août 2017Zimmer Biomet Spine, Inc.Interspinous implants and methods
US977026511 déc. 201426 sept. 2017Roger P. JacksonSplay control closure for open bone anchor
US977027115 juin 201526 sept. 2017Zimmer Biomet Spine, Inc.Spinal implants and methods
US98144953 août 201514 nov. 2017Aro Medical Aps U/StiftelseMethods, systems and apparatuses for torsional stabilization
US20050131411 *4 févr. 200516 juin 2005Culbert Brad S.Method and apparatus for bone fixation with secondary compression
US20050216017 *9 mars 200529 sept. 2005Louie FieldingSpinal implant and method for restricting spinal flexion
US20060009767 *30 juin 200512 janv. 2006Kiester P DExpandable rod system to treat scoliosis and method of using the same
US20060069436 *30 sept. 200430 mars 2006Depuy Spine, Inc.Trial disk implant
US20060085073 *18 oct. 200420 avr. 2006Kamshad RaiszadehMedical device systems for the spine
US20060085074 *19 sept. 200520 avr. 2006Kamshad RaiszadehMedical device systems for the spine
US20060111715 *9 janv. 200625 mai 2006Jackson Roger PDynamic stabilization assemblies, tool set and method
US20060224088 *29 mars 20065 oct. 2006Roche Martin WBody parameter detecting sensor and method for detecting body parameters
US20070016191 *8 déc. 200518 janv. 2007Culbert Brad SMethod and apparatus for spinal stabilization
US20070118132 *15 janv. 200724 mai 2007Triage Medical, Inc.Method and apparatus for spinal fixation
US20070123868 *15 janv. 200731 mai 2007Culbert Brad SMethod and apparatus for spinal fixation
US20070179614 *30 janv. 20062 août 2007Sdgi Holdings, Inc.Intervertebral prosthetic disc and method of installing same
US20070179739 *1 févr. 20062 août 2007Sdgi Holdings, Inc.Implantable pedometer
US20070233065 *17 févr. 20064 oct. 2007Sdgi Holdings, Inc.Dynamic treatment system and method of use
US20070270823 *28 avr. 200622 nov. 2007Sdgi Holdings, Inc.Multi-chamber expandable interspinous process brace
US20070270824 *28 avr. 200622 nov. 2007Warsaw Orthopedic, Inc.Interspinous process brace
US20070270825 *28 avr. 200622 nov. 2007Sdgi Holdings, Inc.Expandable interspinous process implant and method of installing same
US20070270827 *28 avr. 200622 nov. 2007Warsaw Orthopedic, IncAdjustable interspinous process brace
US20070270828 *28 avr. 200622 nov. 2007Sdgi Holdings, Inc.Interspinous process brace
US20070270829 *28 avr. 200622 nov. 2007Sdgi Holdings, Inc.Molding device for an expandable interspinous process implant
US20070276369 *26 mai 200629 nov. 2007Sdgi Holdings, Inc.In vivo-customizable implant
US20080009866 *13 juil. 200710 janv. 2008Todd AlaminMethods and systems for constraint of spinous processes with attachment
US20080021457 *5 juil. 200624 janv. 2008Warsaw Orthopedic Inc.Zygapophysial joint repair system
US20080058808 *11 juin 20076 mars 2008Spartek Medical, Inc.Implant system and method to treat degenerative disorders of the spine
US20080091213 *6 déc. 200717 avr. 2008Jackson Roger PTool system for dynamic spinal implants
US20080108993 *19 oct. 20078 mai 2008Simpirica Spine, Inc.Methods and systems for deploying spinous process constraints
US20080147122 *19 févr. 200819 juin 2008Jackson Roger PDynamic stabilization connecting member with molded inner segment and surrounding external elastomer
US20080167655 *5 janv. 200710 juil. 2008Jeffrey Chun WangInterspinous implant, tools and methods of implanting
US20080177264 *13 juil. 200724 juil. 2008Simpirica Spine, Inc.Methods and systems for laterally stabilized constraint of spinous processes
US20080183211 *2 nov. 200731 juil. 2008Lanx, LlcSpinous process implants and associated methods
US20080262549 *18 avr. 200823 oct. 2008Simpirica Spine, Inc.Methods and systems for deploying spinous process constraints
US20080281360 *10 mai 200713 nov. 2008Shannon Marlece VitturSpinous process implants and methods
US20080281361 *10 mai 200713 nov. 2008Shannon Marlece VitturPosterior stabilization and spinous process systems and methods
US20080294199 *25 mai 200727 nov. 2008Andrew KohmSpinous process implants and methods of using the same
US20080294200 *25 mai 200727 nov. 2008Andrew KohmSpinous process implants and methods of using the same
US20080300633 *30 mai 20084 déc. 2008Jackson Roger PDynamic stabilization connecting member with pre-tensioned solid core
US20080306516 *1 août 200711 déc. 2008Spartek Medical, Inc.Multi-dimensional horizontal rod for a dynamic stabilization and motion preservation spinal implantation system and method
US20080306528 *30 mai 200811 déc. 2008Spartek Medical, Inc.Deflection rod system for spine implant with end connectors and method
US20080306537 *6 juin 200811 déc. 2008Interventional Spine, Inc.Method and apparatus for spinal stabilization
US20080306544 *30 mai 200811 déc. 2008Spartek Medical, Inc.Deflection rod system for a spine implant including an inner rod and an outer shell and method
US20080306545 *30 mai 200811 déc. 2008Spartek Medical, Inc.Deflection rod system for a dynamic stabilization and motion preservation spinal implantation system and method
US20080306548 *1 août 200711 déc. 2008Spartek Medical, Inc.Dynamic stabilization and motion preservation spinal implantation system and method
US20080306556 *1 août 200711 déc. 2008Spartek Medical, Inc.Bone anchor with a curved mounting element for a dynamic stabilization and motion preservation spinal implantation system and method
US20080319488 *29 août 200825 déc. 2008Facet Solutions, Inc.System and method for facet joint replacement
US20080319490 *20 août 200825 déc. 2008Jackson Roger PPolyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US20090012565 *5 juin 20088 janv. 2009Vertech, Inc.Medical device and method to correct deformity
US20090024134 *29 sept. 200822 janv. 2009Facet Solutions, Inc.Surgical measurement and resection framework
US20090024135 *29 sept. 200822 janv. 2009Facet Solutions, Inc.Surgical measurement systems and methods
US20090024166 *8 juil. 200822 janv. 2009Vertech Innovations, Llc.Facet device and method
US20090024167 *29 sept. 200822 janv. 2009Facet Solutions, Inc.Spinal facet implants with mating articulating bearing surface and methods of use
US20090024168 *29 sept. 200822 janv. 2009Facet Solutions, Inc.Linked bilateral spinal facet implants and methods of use
US20090024169 *29 sept. 200822 janv. 2009Facet Solutions, Inc.System and method for multiple level facet joint arthroplasty and fusion
US20090030459 *29 sept. 200829 janv. 2009Facet Solutions, Inc.Spinal facet implant with spherical implant apposition surface and bone bed and methods of use
US20090030461 *29 sept. 200829 janv. 2009Facet Solutions, Inc.Spinal Facet Joint Implant
US20090062918 *30 août 20075 mars 2009Jeffrey Chun WangInterspinous implant, tools and methods of implanting
US20090069813 *7 nov. 200812 mars 2009Interventional Spine, Inc.Method and apparatus for bone fixation with secondary compression
US20090105764 *21 oct. 200823 avr. 2009Jackson Roger PDynamic stabilization member with fin support and solid core extension
US20090105820 *21 oct. 200823 avr. 2009Jackson Roger PDynamic stabilization member with fin support and cable core extension
US20090112207 *15 mai 200830 avr. 2009Blair WalkerSkeletal manipulation method
US20090112262 *15 mai 200830 avr. 2009Scott PoolSkeletal manipulation system
US20090112263 *15 mai 200830 avr. 2009Scott PoolSkeletal manipulation system
US20090187120 *18 janv. 200823 juil. 2009Warsaw Orthopedic, Inc.Implantable sensor and associated methods
US20090198282 *2 févr. 20096 août 2009Louis FieldingSpinal implant and method for restricting spinal flexion
US20090204154 *9 avr. 200913 août 2009Ellipse Technologies, Inc.expandable rod system to treat scoliosis and method of using the same
US20090240280 *19 mars 200824 sept. 2009Jeffrey Chun WangInterspinous implant, tools and methods of implanting
US20090264932 *17 avr. 200922 oct. 2009Simpirica Spine, Inc.Methods and systems for constraint of multiple spine segments
US20090281574 *19 juin 200912 nov. 2009Jackson Roger PDynamic stabilization assembly with frusto-conical connection
US20100010543 *15 sept. 200914 janv. 2010Jackson Roger PDynamic stabilization connecting member with floating core, compression spacer and over-mold
US20100023060 *5 juin 200928 janv. 2010Simpirica Spine, Inc.Methods and apparatus for locking a band
US20100030224 *24 sept. 20094 févr. 2010Spartek Medical, Inc.Surgical tool and method for connecting a dynamic bone anchor and dynamic vertical rod
US20100030267 *24 sept. 20094 févr. 2010Spartek Medical, Inc.Surgical tool and method for implantation of a dynamic bone anchor
US20100030271 *24 sept. 20094 févr. 2010Spartek Medical, Inc.Modular in-line deflection rod and bone anchor system and method for dynamic stabilization of the spine
US20100030274 *24 sept. 20094 févr. 2010Spartek Medical, Inc.Dynamic spinal rod and method for dynamic stabilization of the spine
US20100030279 *24 sept. 20094 févr. 2010Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post and axial spring and method for dynamic stabilization of the spine
US20100036421 *24 sept. 200911 févr. 2010Spartek Medical, Inc.Load-sharing component having a deflectable post and method for dynamic stabilization of the spine
US20100036424 *4 août 200911 févr. 2010Simpirica Spine, Inc.Methods and systems for increasing the bending stiffness and constraining the spreading of a spinal segment
US20100036426 *24 sept. 200911 févr. 2010Spartek Medical, Inc.Versatile offset polyaxial connector and method for dynamic stabilization of the spine
US20100036435 *24 sept. 200911 févr. 2010Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post and method for dynamic stabilization of the spine
US20100036436 *24 sept. 200911 févr. 2010Spartek Medical, Inc.Load-sharing bone anchor having a durable compliant member and method for dynamic stabilization of the spine
US20100036437 *24 sept. 200911 févr. 2010Spartek Medical, Inc.Load-sharing bone anchor having a deflectable post with a compliant ring and method for stabilization of the spine
US20100057139 *10 nov. 20094 mars 2010Spartek Medical, Inc.Bone anchor for receiving a rod for stabilization and motion preservation spinal implantation system and method
US20100057140 *10 nov. 20094 mars 2010Spartek Medical, Inc.Bone anchor for receiving a rod for stabilization and motion preservation spinal implantation system and method
US20100094302 *13 oct. 200815 avr. 2010Scott PoolSpinal distraction system
US20100094303 *13 oct. 200815 avr. 2010Arvin ChangSpinal distraction system
US20100094304 *13 oct. 200815 avr. 2010Scott PoolSpinal distraction system
US20100094305 *13 oct. 200815 avr. 2010Arvin ChangSpinal distraction system
US20100094306 *13 oct. 200815 avr. 2010Arvin ChangSpinal distraction system
US20100094344 *14 oct. 200815 avr. 2010Kyphon SarlPedicle-Based Posterior Stabilization Members and Methods of Use
US20100121323 *10 nov. 200913 mai 2010Ellipse Technologies, Inc.External adjustment device for distraction device
US20100168795 *24 sept. 20091 juil. 2010Spartek Medical, Inc.Load-sharing bone anchor having a natural center of rotation and method for dynamic stabilization of the spine
US20100174314 *12 janv. 20108 juil. 2010Srdjan MirkovicMethod and apparatus for spinal stabilization
US20100191071 *23 janv. 200929 juil. 2010Warsaw Orthopedic, Inc.Methods and Systems for Diagnosing, Treating, or Tracking Spinal Disorders
US20100191088 *23 janv. 200929 juil. 2010Warsaw Orthopedic, Inc.Methods and systems for diagnosing, treating, or tracking spinal disorders
US20100191100 *23 janv. 200929 juil. 2010Warsaw Orthopedic, Inc.Methods and systems for diagnosing, treating, or tracking spinal disorders
US20100191297 *20 janv. 201029 juil. 2010Spartek Medical, Inc.Systems and methods for injecting bone filler into the spine
US20100217271 *23 févr. 200926 août 2010Ellipse Technologies, Inc.Spinal distraction system
US20100234894 *10 mars 201016 sept. 2010Simpirica Spine, Inc.Surgical tether apparatus and methods of use
US20100249837 *26 mars 200930 sept. 2010Kspine, Inc.Semi-constrained anchoring system
US20100268281 *26 avr. 201021 oct. 2010Abdou M SamyDevices and methods for inter-vertebral orthopedic device placement
US20100312343 *24 mai 20109 déc. 2010Linares Medical Devices, LlcTip support insert for application to left/right articular processes to minimize abrasion between vertebrae and to maintain proper angle/lift for reducing nerve compression
US20100318129 *16 juin 200916 déc. 2010Kspine, Inc.Deformity alignment system with reactive force balancing
US20100324688 *18 juin 200923 déc. 2010MekatronixIntervertebral spinal disc prosthesis
US20100331891 *23 juin 201030 déc. 2010Interventional Spine, Inc.System and method for spinal fixation
US20110054536 *1 sept. 20103 mars 2011Kspine, Inc.Growth directed vertebral fixation system with distractible connector(s) and apical control
US20110060336 *3 sept. 201010 mars 2011Ellipse Technologies, Inc.Bone growth device and method
US20110066188 *15 sept. 200917 mars 2011Kspine, Inc.Growth modulation system
US20110077692 *19 nov. 201031 mars 2011Jackson Roger PDynamic spinal stabilization assemblies, tool set and method
US20110118565 *27 janv. 201119 mai 2011Roche Martin WMethod for Detecting Body Parameters
US20110118566 *27 janv. 201119 mai 2011Roche Martin WMethod for Detecting Body Parameters
US20110118567 *28 janv. 201119 mai 2011Roche Martin WMethod for Detecting Body Parameters
US20110118783 *5 oct. 201019 mai 2011Spartek Medical, Inc.Load-sharing bone anchor having a flexible post and method for dynamic stabilization of the spine
US20110124981 *27 janv. 201126 mai 2011Roche Martin WMethod for Detecting Body Parameters
US20110125269 *31 déc. 201026 mai 2011Moskowitz Nathan CTotal artificial spino-laminar prosthetic replacement
US20110125270 *23 nov. 200926 mai 2011David C PaulProsthetic Spinal Disc Replacement
US20110152933 *25 févr. 201123 juin 2011Interventional Spine, Inc.Method and apparatus for spinal stabilization
US20110172708 *28 mars 201114 juil. 2011Simpirica Spine, Inc.Methods and systems for increasing the bending stiffness of a spinal segment with elongation limit
US20110184245 *28 janv. 201028 juil. 2011Warsaw Orthopedic, Inc., An Indiana CorporationTissue monitoring surgical retractor system
US20110213221 *30 janv. 20111 sept. 2011Roche Martin WMethod for Detecting Body Parameters
US20120191192 *9 déc. 200926 juil. 2012Industry Foundation Of Chonnam National UniversityImage-based patient-specific medical spinal surgery method and spinal prosthesis
USRE4643115 août 201413 juin 2017Roger P JacksonPolyaxial bone anchor with helical capture connection, insert and dual locking assembly
CN102573678A *30 août 201011 juil. 2012科斯班公司Spinal growth modulation system
CN102740771A *10 nov. 201017 oct. 2012皮埃尔和玛利居里大学(巴黎第六大学)Device for measuring the activity of the spinal cord of a vertebra
CN103140168A *23 mai 20115 juin 2013药物代谢动力公司A method and apparatus for an implantable inertial-based sensing system for real-time, in vivo detection of spinal pseudarthrosis and adjacent segment motion
CN103501715A *1 déc. 20118 janv. 2014费瑟特-链接公司Fusion implant for facet joints
CN104055607A *20 mars 201324 sept. 2014江阴瑞康健生物医学科技有限公司Artificial lamina
EP2460481A1 *1 déc. 20106 juin 2012FACET-LINK Inc.Fusion implant for facet joints
EP2510873A3 *29 mars 200628 nov. 2012Martin RocheBiometric sensor
EP2722013A4 *20 juin 201219 août 2015Univ AkitaSpine immobilization tool
WO2007098385A3 *16 févr. 20078 mai 2008Warsaw Orthopedic IncDynamic treatment system and method of use
WO2009052315A3 *16 oct. 20085 nov. 2009Robie Device Group, LlcMethods, systems and apparatuses for torsional stabiliazation
WO2010059202A1 *18 nov. 200927 mai 2010Wasielewski Ray CMethod of designing orthopedic implants using in vivo data
WO2010141293A2 *26 mai 20109 déc. 2010Linares Medical Devices, LlcTip support insert for application to left/right articular processes to minimize abrasion between vertebrae and to maintain proper angle/lift for reducing nerve compression
WO2010141293A3 *26 mai 201031 mars 2011Linares Medical Devices, LlcTip support insert for application to left/right articular processes to minimize abrasion between vertebrae and to maintain proper angle/lift for reducing nerve compression
WO2010147744A1 *27 mai 201023 déc. 2010Kspine, Inc.Deformity alignment system with reactive force balancing
WO2011034714A1 *30 août 201024 mars 2011Kspine, Inc.Spinal growth modulation system
WO2011057765A1 *10 nov. 201019 mai 2011Universite Pierre Et Marie Curie (Paris 6)Device for measuring the activity of the spinal cord of a vertebra
WO2011149845A2 *23 mai 20111 déc. 2011Pharmaco-Kinesis CorporationA method and apparatus for an implantable inertial-based sensing system for real-time, in vivo detection of spinal pseudarthrosis and adjacent segment motion
WO2011149845A3 *23 mai 201119 janv. 2012Pharmaco-Kinesis CorporationA method and apparatus for an implantable inertial-based sensing system for real-time, in vivo detection of spinal pseudarthrosis and adjacent segment motion
WO2012072733A1 *1 déc. 20117 juin 2012Facet-Link Inc.Fusion implant for facet joints
Classifications
Classification aux États-Unis623/17.11
Classification internationaleA61F2/44
Classification coopérativeA61B2090/064, A61B2017/0256, A61B17/707, A61B17/7004, B33Y80/00, A61B17/7064, A61B17/7053, A61B2017/564, A61B17/7067, A61B2017/681
Classification européenneA61B17/70E, A61B17/70P2, A61B17/70P6
Événements juridiques
DateCodeÉvénementDescription
8 févr. 2008ASAssignment
Owner name: VERTECH INNOVATIONS, L.L.C., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ROSENBERG, MEIR;REEL/FRAME:020485/0163
Effective date: 20050808
15 févr. 2008ASAssignment
Owner name: VERTECH, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:VERTECH INNOVATIONS, LLC;REEL/FRAME:020535/0818
Effective date: 20080211
Owner name: VERTECH, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SACHS, DAN;REEL/FRAME:020535/0849
Effective date: 20080207
Owner name: VERTECH, INC.,MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SACHS, DAN;REEL/FRAME:020535/0849
Effective date: 20080207
18 févr. 2009ASAssignment
Owner name: K SPINE, INC., MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:VERTECH, INC.;REEL/FRAME:022279/0235
Effective date: 20080923
Owner name: K SPINE, INC.,MINNESOTA
Free format text: CHANGE OF NAME;ASSIGNOR:VERTECH, INC.;REEL/FRAME:022279/0235
Effective date: 20080923
11 juin 2015ASAssignment
Owner name: K2M, INC., VIRGINIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SILICON VALLEY BANK;REEL/FRAME:035891/0052
Effective date: 20150521
Owner name: K2M, INC., VIRGINIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:K SPINE, INC.;REEL/FRAME:035889/0140
Effective date: 20150521
2 juil. 2015ASAssignment
Owner name: K2M, INC., VIRGINIA
Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 035889 FRAME: 0140. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT;ASSIGNOR:K SPINE, INC.;REEL/FRAME:036139/0317
Effective date: 20150521