US20090308907A1 - Partially reusable surgical stapler - Google Patents
Partially reusable surgical stapler Download PDFInfo
- Publication number
- US20090308907A1 US20090308907A1 US12/137,571 US13757108A US2009308907A1 US 20090308907 A1 US20090308907 A1 US 20090308907A1 US 13757108 A US13757108 A US 13757108A US 2009308907 A1 US2009308907 A1 US 2009308907A1
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- US
- United States
- Prior art keywords
- stapler
- lower jaw
- latching member
- actuator module
- surgical stapler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B17/07207—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously the staples being applied sequentially
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/0023—Surgical instruments, devices or methods, e.g. tourniquets disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B2017/07214—Stapler heads
- A61B2017/0725—Stapler heads with settable gap between anvil and cartridge, e.g. for different staple heights at different shots
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/072—Surgical staplers, e.g. containing multiple staples or clamps for applying a row of staples in a single action, e.g. the staples being applied simultaneously
- A61B2017/07214—Stapler heads
- A61B2017/07285—Stapler heads characterised by its cutter
Definitions
- the present invention relates generally to surgical stapling instruments and, more particularly, to a surgical stapler which can be disassembled and portions reconditioned and sterilized for reuse in subsequent surgical procedures, and which includes a removable actuating module that can be reused with multiple staple cartridges during a single patient procedure.
- a partially reusable surgical stapler for deploying staples into tissue.
- the stapler has a body with a distal end, a proximal end and a longitudinal axis therebetween.
- the proximal end includes a handle while the distal end includes a staple cartridge holder and an opposing anvil.
- the stapler also has an actuator module for deploying staples.
- the actuator module includes at least one longitudinally movable member for sequentially ejecting staples towards the anvil.
- the actuator module is readily removable and replaceable to and from the body.
- the present invention provides a partially reusable surgical stapler having an upper jaw member with a proximal handle end and a distal anvil end.
- a lower jaw member having a proximal channel-shaped frame and a distal staple cartridge channel is aligned with the upper jaw.
- An actuator module having at least one longitudinally moveable member for sequentially ejecting staples towards the anvil, is readily removable and replaceable to and from the lower jaw frame.
- a staple cartridge containing a plurality of staples is removably disposed within the staple cartridge channel.
- a latching member for connecting the upper and lower jaws together is provided at an intermediate position along a longitudinal axis of the stapler.
- the latching member is moveable relative to the upper and lower jaw members to place the stapler in a series of different locking states.
- the different locking states include an assembly state for connecting and disconnecting the latching member to the jaw members, and a closed, latched state in which the latching member is locked to the jaw members.
- FIG. 1 is an isometric view of an exemplary surgical stapler showing the stapler in a closed position
- FIG. 2 is a front view of the stapler in an open position
- FIG. 3 is an isometric view of the stapler in an open position
- FIG. 4 is an isometric bottom view of the reusable upper jaw member for the stapler
- FIG. 5 is an isometric top view of the stapler upper jaw member
- FIG. 6 is an isometric view of the reusable lower jaw member including the cartridge channel
- FIG. 7 is an isometric view of the disposable staple cartridge
- FIG. 8 is a bottom view of the disposable staple cartridge
- FIG. 9 is an isometric view of the reusable latching member
- FIG. 10 is a front view of the reusable latching member
- FIG. 11 is a detailed isometric view of the distal end of the latching member
- FIG. 12 is a partial front view of the stapler showing the latching member in a ready to assemble state
- FIG. 13 is a partial front view of the stapler showing the latching member in an initial inserted state
- FIG. 14 is a partial front view of the stapler showing the latching member in a rotated and partially locked-in state
- FIG. 15 is a partial front view of the stapler showing the relative positions of the latching and upper jaw members in a pre-close position
- FIG. 16 is a partial front view of the stapler showing the relative positions of the latching and upper jaw members in an open position during use;
- FIG. 17 is an isometric view of the disposable actuating module
- FIG. 18 is another isometric view of the disposable actuating module looking forward from the proximal to the distal end;
- FIG. 19 is an isometric view of the actuating module pan
- FIG. 20 is a detailed, isometric view of the proximal end of the actuating module
- FIG. 21 is a top view of the actuating module
- FIG. 22 is an isometric view of the actuating knob
- FIG. 23 is an isometric view of the guide block
- FIG. 24 is an isometric view of a pusher bar
- FIG. 25 is an isometric view of the knife support bar
- FIG. 26 is a close-up, isometric view of the distal end of the actuating module showing the protector cap;
- FIG. 27 is a front view of the actuating module
- FIG. 28 is a sectional view of the actuating module proximal end, showing the relationship between the actuating knob and the detent spring in a full back position;
- FIG. 29 is a sectional view of the actuating module proximal end, showing the actuating knob moved forward during firing.
- FIGS. 1 through 3 illustrate a first exemplary surgical stapler 20 of the present invention.
- the body of stapler 20 includes an upper jaw member 22 , a lower jaw member 24 , and a latching member 30 .
- Latching member 30 is pivotable relative to the upper and lower jaws members 22 , 24 , as shown in FIGS. 2-3 .
- Latching member 30 can be pivoted through a series of different latching states to lock the stapler closed for use or to open the stapler varying degrees to allow for adjustment of tissue within the stapler, the replacement of a staple cartridge, or disassembly of the stapler.
- latching member 30 can be pivoted to a fully open position to allow stapler 20 to be disassembled in preparation for the resterilization and reuse of portions of the stapler.
- upper jaw 22 comprises a single piece, elongated channel-shaped frame having a pair of opposing sidewalls 32 a , 32 b connected by a top wall 36 .
- Top wall 36 is suitably shaped on the outer surface to form a hand grip and includes an upper handle protrusion 40 to facilitate the handling and operation of the stapler by a surgeon.
- the distal end of upper jaw 22 comprises a pair of inwardly extending flanges 42 which define an anvil 44 of the stapler. Flanges 42 are separated by a central, longitudinal slot 46 which extends along the entire length of anvil 44 .
- the inner surface of each flange 42 is provided with two longitudinal rows of uniformly spaced staple-forming pockets 50 .
- Staple forming pockets 50 allow the fashioning of B-form staples when U-shaped staples are ejected against the anvil flanges during firing.
- Anvil 44 includes a tapered tip at the distal-most end for facilitating insertion of the stapler into hollow, tubular body organs.
- a pair of tissue stops 52 is provided on opposite sides of anvil 44 adjacent the proximal end of staple forming pockets 50 . Tissue stops 52 are laterally aligned with the proximal end of staple forming pockets 50 to prevent tissue from being placed into the stapler beyond anvil 44 . Blocking tissue at the proximal end of anvil 44 prevents the pinching or cutting of unstapled tissue.
- Cylindrical pins 54 extend from opposite sides of upper jaw 22 proximal of tissue stops 52 . Pins 54 fit inside vertical slots on lower jaw 24 to connect the upper and lower jaws together.
- Upper jaw 22 also includes a pair of curved notches 60 near the proximal end of channel sidewalls 32 a , 32 b . Notches 60 interact with projections 62 on lower jaw 24 , as shown in FIG. 2 , to provide a means for easily aligning the jaws during use.
- Upper jaw 22 is preferably comprised of a single piece of a biocompatible metal, such as, for example, stainless steel. Using a single piece of material for upper jaw 22 increases the structural integrity of the stapler. Alternatively, upper jaw 22 can be manufactured as two or more separate pieces that are joined together during the manufacturing process by known joining methods such as, for example, welding.
- lower jaw 24 comprises a single piece, elongated U-shaped frame having a pair of sidewalls 64 a , 64 b connected by a bottom wall 66 .
- side walls 64 a , 64 b are reduced in size to form a cartridge channel 70 for supporting a single use staple cartridge within the stapler.
- Notches 72 are provided in sidewalls 64 a , 64 b adjacent the distal end of cartridge channel 70 . Notches 72 engage side projections on the staple cartridge to hold the cartridge within the channel.
- Vertical alignment slots 56 are located proximal of cartridge channel 70 in the upper edge of sidewalls 64 a , 64 b .
- pins 54 on upper jaw 22 interface with alignment slots 56 to align and connect the jaw members together.
- the width between upper jaw sidewalls 32 a , 32 b is slightly greater than the width between lower jaw sidewalls 64 a , 64 b to enable the upper jaw to fit over the lower jaw when pins 54 are inserted into alignment slots 56 , and projections 62 into notches 60 .
- Indentations 74 are formed in the outer surface of sidewalls 64 a , 64 b , distal of alignment slots 56 . Indentations 74 facilitate the attachment of an actuating module to lower jaw member 24 , as will be described in further detail below.
- An opening 76 is formed through bottom wall 66 at an intermediate position along lower jaw 24 .
- Sidewalls 64 a , 64 b extend downward on opposite sides of opening 76 to form distally angled projections 80 .
- sidewalls 64 a , 64 b are shaped to form a straight-sided slot 82 having a circular end 88 .
- the diameter of circular end 88 is slightly larger than the width of the slot 82 .
- Proximal of projections 80 the outer surfaces of sidewalls 64 a , 64 b include a latching member positioning feature. As shown in FIG.
- the positioning feature can comprise a plurality of detent bumps 84 , or other surface indentations, that are machined into the surface of the sidewalls 64 a , 64 b .
- FIG. 6 shows only a positioning feature on the front side of lower jaw 24 , however, it should be understood that the back side of the lower jaw is fashioned in the same manner so that latching member 30 may be retained in a series of latching states by both sides of the lower jaw, as will be described below.
- a retention feature 86 is formed at the proximal end of lower jaw 24 at the junction between sidewalls 64 a , 64 b and bottom wall 66 . Retention feature 86 can comprise an inward expansion of sidewalls 64 a , 64 b which facilitates a snap connection with an actuating module during assembly of stapler 20 .
- FIGS. 7 and 8 show an exemplary removable staple cartridge 90 for use in stapler 20 of the invention.
- Cartridge 90 is adapted to receive a plurality of surgical staples arranged in at least two laterally spaced longitudinal rows.
- Cartridge 90 has a body which includes opposite side walls 92 a , 92 b configured to be slidably received in the interior of lower jaw cartridge channel 70 .
- Staple cartridge 90 is divided longitudinally by a central elongated slot 94 which extends from the proximal end of the cartridge toward its distal end.
- a plurality of staple openings 96 defined by the cartridge body, are disposed along the elongated center slot 94 .
- the distal end of staple cartridge 90 includes a tapered tip to facilitate the insertion of lower jaw member 24 into a hollow tubular body organ.
- staple cartridge 90 Proximal of the tapered tip, staple cartridge 90 is provided with a pair of outwardly extending protrusions 102 .
- a pair of spaced, parallel flanges 104 extends rearward from opposite sides of staple cartridge 90 .
- Legs 110 extend downward from flanges 104 at the proximal end of the staple cartridge. Each leg 110 is provided with a rounded, downwardly facing notch 112 .
- Leg notches 112 engage a pin on latching member 30 , as will be described below, to hold the cartridge within lower jaw channel 70 .
- a pair of wings 114 extends upward and outward from sidewalls 92 a , 92 b at the proximal end of cartridge 90 . Wings 114 function as finger grips which allow staple cartridge 90 to be manually inserted into and removed from lower jaw 24 . Using wings 114 , cartridge 90 can be lifted out of jaw opening 76 and notches 72 , to remove the cartridge from lower jaw 24 following use. Additionally, wings 114 engage lower jaw sidewalls 64 a , 64 b at the proximal end of cartridge channel 70 , as shown in FIG. 3 , to lock the cartridge in place within lower jaw 24 .
- stapler 20 includes a latching member 30 for connecting the upper and lower jaws members together at an intermediate position along the longitudinal length of the stapler.
- jaw members 22 , 24 are connected together at a location adjacent to the proximal ends of anvil 44 and staple cartridge 90 .
- latching member 30 comprises a single piece, channeled-shaped frame having opposing side walls 124 a , 124 b connected by a top wall 130 .
- Latching member 30 further includes a latch pin 122 for pivotally connecting the latching member to lower jaw 24 .
- the latching member is comprised of a single piece of stainless steel, or another similar biocompatible metal.
- latching arm 120 includes a handle extension 134 .
- handle extension 134 When connected to lower jaw member 24 , handle extension 134 combines with upper jaw handle extension 40 to form a hand grip for manipulation of the stapler by a surgeon.
- Each side wall 124 a , 124 b of latching member 30 includes a distally-extending C-shaped hook member 140 provided with a forwardly facing notch 142 for engaging upper jaw pins 54 .
- hook members 140 include an inner cam surface 144 extending rearward from the tip of the hook member into notch 142 .
- latching member 30 is moved to a closed, operative state, notches 142 engage upper jaw pins 54 , acting as an over-center latch to maintain the latching member in the latched state.
- each hook member 140 projects distally downward, beyond the end of latching member top wall 130 .
- Latch pin 122 extends between the down turned ends of hook members 140 , as shown in FIG.
- Latch pin 122 has a cylindrical shape with flat surfaces 152 adjacent each end. The diameter of latch pin 122 is greater than the narrow opening for lower jaw slot 82 .
- Latching member 30 is detachably connected to lower jaw 24 by inserting latch pin 122 into lower jaw slot 82 .
- Latch pin 122 is inserted into slot 82 by orienting latching member 30 so that flat ends 152 lie in parallel with the straight sides of the slot. In this position, latch pin 122 can be inserted into slot 82 despite the pin diameter being greater than the slot width. With flat ends 152 aligned with the linear sides of slot 82 , latch pin 122 is inserted into the slot, as shown in FIG. 12 , until the pin rests within circular slot end 88 , as shown in FIG. 13 .
- Stapler 20 also includes means for retaining the latching member in a series of different latching states.
- the retaining means includes a spring arm 150 extending from the top edge of each latching arm sidewall 124 a , 124 b .
- Spring arm 150 curves distally upward, following the upper contour of hook member 140 , and includes a bulbous free end.
- latching member 30 As latching member 30 rotates, hook members 140 are drawn along the sides of lower jaw member 24 . As hook members 140 swing alongside lower jaw sidewalls 64 a , 64 b , the bulbous ends of spring arms 150 contact detent bumps 84 on the sidewalls. To move spring arms 150 between the detent bumps 84 , additional force is applied to latching member 30 to cause the spring arms to flex towards the hook members 140 , so that the ends of the spring arms can ride over the bumps. With spring arms 150 positioned between detent bumps 84 , as shown in FIG. 14 , latching member 30 is in a partially locked-in state. In the partially locked-in state, latching member 30 is attached to lower jaw 24 and alignment slots 56 are just distal of the tip of hook members 140 . Upper jaw pins 54 can be freely inserted or removed from lower jaw slots 56 , allowing the upper and lower jaw members to be separated and rejoined together.
- latching member 30 and upper and lower jaw members 22 , 24 are connected together to form the body of stapler 20 , but upper jaw pins 54 can slide within slots 56 , between the bottom of the slot and cam surface 144 , to allow some relative movement between the jaw members.
- Latching member 30 maintains the jaw members in a loosely latched position to permit relative movement between the staple cartridge and anvil. The relative movement at the distal end of jaw members 22 , 24 allows for tissue adjustments without disconnecting the jaw members from each other.
- latching member 30 When latching member 30 is rotated to a closed, operative state (shown in FIG. 1 ) the latching member surrounds lower jaw member 24 , and pins 54 on upper jaw member 22 are lodged within hook member notches 142 . Spring arms 150 advance distally upward along the sides of lower jaw member 24 beyond detent bumps 84 . In this state, the upper and lower jaw members are locked together to compress tissue between the anvil and cartridge surfaces, and the stapler is ready for stapling and cutting tissue. In the closed state, a minimum spacing may be maintained between the anvil and cartridge surfaces by a spacer pin 160 . To adjust the placement of tissue between the anvil and cartridge surfaces, latching member 30 can be rotated back to the pre-close state, as shown in FIG.
- latching member 30 is rotated away from lower jaw member 24 to draw upper jaw pins 54 out of hook notches 142 .
- Latching member 30 may be rotated away from upper and lower jaw members 22 , 24 by pulling on the curved latching arm tip 162 .
- spring arms 150 move through detent bumps 84 , enabling hook members 140 to swing through and way from the lower jaw sidewalls 64 a , 64 b .
- Latching member 30 is rotated around in the direction of staple cartridge 90 until latching member 30 returns to the initial, open position shown in FIG. 13 .
- latching member 30 With latching member 30 in the open state, flat ends 152 on latch pin 122 are again aligned in parallel with the straight sides of slot 82 , enabling the latch pin to be withdrawn through slot 82 to separate the latching member from lower jaw member 24 . With latching member 30 detached, stapler 20 can be disassembled into three separate, one-piece components, namely, upper jaw 22 , lower jaw 24 and latching member 30 .
- the one-piece channel-shaped construction of these reusable components provides for easy yet thorough reconditioning and sterilization of the components between uses.
- FIGS. 17 and 18 show an actuator module 170 for stapling and cutting tissue clamped between the upper and lower jaw members 22 , 24 .
- Actuator module 170 comprises a U-shaped, longitudinal module pan 172 which provides the supporting structure for the actuator module components.
- Module pan 172 includes a pair of sidewalls 174 connected together by a bottom wall 176 ( FIG. 19 ). The distance between module pan sidewalls 174 is less than the distance between lower jaw sidewalls 64 a , 64 b to enable the module pan to be slidably mounted within the proximal channel of lower jaw 24 . As shown in FIGS.
- the proximal end of module pan 170 includes one or more detent bumps 178 protruding from the outer surface of sidewalls 174 .
- Detent bumps 178 engage retention features 86 on the inside channel of lower jaw member 24 when the actuator module 170 is slid proximally into the lower jaw channel. The interaction of detent bumps 178 with retention features 86 snaps and retains the actuator module in place within lower jaw member 24 .
- a plurality of moveable actuating members are situated within module pan 172 for longitudinal movement within the pan relative to upper and lower jaw members 22 , 24 .
- the actuating members include a pusher block 180 which is disposed within module pan 172 for reciprocal, longitudinal movement within the pan.
- Pusher block 180 is attached to an actuator knob 182 by a lateral flange 184 .
- flange 184 extends through an elongated guide slot 186 formed in a sidewall 64 of the lower jaw.
- Flange 184 positions knob 182 on the outside of jaw members 22 , 24 to allow manual access of the knob.
- knob 182 is shown extending through a guide slot 186 in lower jaw sidewall 64 b .
- a guide slot could also be formed in the opposite lower jaw sidewall 64 a , in which case actuating knob 182 would extend out the opposite side of stapler 20 .
- Flange 184 extends through and rides along guide slot 186 as knob 182 is manually moved along the outside of jaw members 22 , 24 .
- actuator module 170 also includes a pair of longitudinally extending, parallel pusher bars 190 .
- the proximal ends of pusher bars 190 are secured within laterally spaced pusher block slots 192 (shown in FIG. 22 ) to allow the pusher bars to move longitudinally with pusher block 180 through module pan 172 .
- Pusher bars 190 extend distally from pusher block 180 and are slidably received in longitudinal slots 194 formed in a guide block 200 , shown in FIG. 23 .
- guide block 200 is mounted at the distal end of module pan 172 .
- the upper edges of module pan sidewalls 174 are bent inward over the side edges of guide block 200 to retain the guide block within the module pan.
- tabs 202 extend from the sides of guide block 200 through openings 204 in module pan sidewalls 174 to secure the guide block within the pan.
- the distal end of guide block 200 extends beyond the end of module pan 172 and between rear flanges 104 of staple cartridge 90 .
- Lateral slots 194 within guide block 200 align pusher bars 190 with the elongated staple driver slots 100 of staple cartridge 90 .
- the distal ends of pusher bars 190 extend forward of guide slots 194 and are provided with a wedge-shaped tip 206 , shown in FIG. 24 , which defines an inclined cam surface for engaging the staple drivers within cartridge 90 as the pusher bars are moved distally through the cartridge.
- the longitudinal movement of the pusher bar tips 206 sequentially drives the staple drivers, through a camming action, to fire staplers from the cartridge.
- guide block 200 includes a depending center section 210 which extends downward through opening 76 in the lower jaw bottom wall 66 .
- Center section 210 includes a distally angled, straight-sided slot 212 with a circular end 218 .
- guide block slot 212 is longitudinally aligned with slot 82 in lower jaw sidewalls 64 a , 64 b to enable latch pin 122 to engage both lower jaw 24 and guide block 200 when latching member 30 is connected to the stapler.
- latch pin 122 is inserted through slot 82 into slot end 88 , the pin also passes through guide block slot 212 and lodges within circular end 218 , locking the actuator module 170 and lower jaw 24 together.
- actuator module 170 further comprises a knife support bar 214 positioned between pusher bars 190 .
- Knife support bar 214 and pusher bars 190 are preferably manufactured as sheet metal components.
- the proximal end of knife support bar 214 is secured within a center slot 216 of pusher block 180 ( FIG. 22 ) to connect the knife support bar to the pusher block for movement by firing knob 182 .
- knife support bar 214 is slidably received in a center slot 220 formed in guide block 200 (shown in FIG. 23 ) to align the knife support bar with the elongated center slot 94 of the staple cartridge. As shown in FIG.
- an inclined knife blade 222 having a beveled cutting edge is located at the front end of knife support bar 214 .
- the beveled cutting edge of knife blade 222 is oriented at an angle relative to jaw members 22 , 24 , and is slidably received in central longitudinal slot 220 of guide block 200 .
- knife support bar 214 includes a cartridge locking notch 228 and a locking cut out section 224 , which are part of a safety lockout mechanism described below.
- the proximal end of knife support bar 214 includes an offset section, indicated by reference number 226 . Knife offset 226 is formed by cutting away a section of the knife support bar 214 near the proximal end, to produce two elevated points 230 , 232 on the support bar.
- a protector cap 234 covers the distal end of guide block 200 .
- a center section 236 of cap 234 surrounds knife blade 222 and the wedged tips 206 of pusher bars 190 .
- An inwardly directed lip 240 extends along the bottom edge of the cap. During assembly, downward pressure is applied to protector cap 234 to snap the distal end of the actuator module in place inside the lower jaw channel. As cap 234 is pressed downward, cap lip 240 snaps into indentations 74 on the outer surface of lower jaw 24 .
- a leaf spring 250 shown in FIG. 19 , is integrated into module pan bottom wall 176 beneath guide block 200 .
- Spring 250 provides a safety lockout feature by lifting knife support bar cut out 224 against guide block 200 after firing, to prevent re-firing of a used cartridge.
- a second spring 252 is integrated into module pan bottom wall 176 near the proximal end of the pan. This second spring 252 is a detent spring that interacts with a notch on pusher block 180 to prevent forward movement of actuator knob 182 during shipping, and to provide audible and tactile feedback when the actuator knob is returned to the proximal-most position in the module pan following firing.
- FIGS. 28 and 29 illustrate the operation of detent spring 252 in greater detail. In FIG.
- FIG. 29 shows detent spring 252 disengaged from notch 254 by the application of an intentional, distally directed force on actuator knob 182 .
- Pusher bars 190 and knife support bar 214 are advanced distally by applying sufficient force to actuator knob 182 to overcome the force of spring 252 against notch 254 .
- pusher block 180 can slide distally through module pan 172 to first advance pusher bars 190 and then advance knife support bar 214 from guide block 200 into staple cartridge 90 .
- a downwardly directed edge of pusher block 180 is in contact with knife support bar 214 at the proximal end point 232 of offset section 226 .
- Actuating knob 182 is retracted to a fully proximal position within guide slot 186 , thereby placing pusher bars 190 and knife blade 222 within slots 194 and 220 of guide block 200 .
- spring 252 disengages from notch 254 , enabling pusher block 180 to advance longitudinally within module pan 172 .
- the block advances pusher bars 190 distally, causing the inclined tips of the bars to advance into cartridge driver slots 100 .
- Knife support bar 214 thus remains stationary during the initial distal movement of the pusher bars 190 and block 180 .
- Knife blade 222 and pusher bar tips 206 advance simultaneously through staple cartridge 90 driving staples through openings 96 and cutting tissue. Knife blade 222 is advanced into staple cartridge 90 slightly behind pusher bars 190 so that staples are formed into the tissue gripped between the anvil and cartridge prior to the knife blade advancing and cutting the tissue between the staple rows.
- pusher block 180 is retracted within module pan 172 by drawing the actuating knob back proximally through jaw guide slot 186 .
- pusher bars 190 are drawn proximally while knife support bar 214 remains in a distal, stationary position due to the offset section 226 in the support bar.
- the knife support bar 214 begins to retract proximally with the pusher block and bars.
- knife support bar 214 retracts within guide block 200 , the support bar is lifted up by leaf spring 250 into contact with the guide block, until the knife locking cut out 224 catches a center post 256 ( FIG. 23 ) of the guide block. Once knife cut out 224 engages guide block post 256 , knife support bar 214 is prevented from further movement in conjunction with pusher block 180 . Preferably, knife support bar 214 engages locking cut out section 224 as pusher block 180 and pusher bars 190 are reaching the fully proximal position.
- latching member 30 is pivoted relative to jaw members 22 , 24 to separate the upper and lower jaws, as described above.
- staple cartridge 90 can be removed and replaced with a new cartridge.
- the used cartridge can be removed by pulling up on cartridge wings 114 to dislodge cartridge legs 110 from lower jaw opening 76 .
- cartridge leg notches 112 FIG. 7
- the cartridge can be slid distally out of cartridge channel 70 and discarded.
- a new staple cartridge 90 can be loaded into lower jaw 24 by pushing the flanged, distal end of the cartridge against the distal end of the lower jaw cartridge channel 70 , and pushing down on wings 114 to lower legs 110 through jaw opening 76 .
- Cartridge legs 110 are pushed through lower jaw opening 76 until leg notches 112 snap onto latch pin 122 .
- lockout pin 106 on the cartridge depresses knife support bar 214 at locking notch 228 against the counter force of leaf spring 250 .
- the force of lockout pin 106 pushes knife support bar cutout 224 down and out of contact with guide block center post 256 .
- the stapler can be reassembled by placing upper jaw 22 over lower jaw 24 and reinserting upper jaw pins 54 into lower jaw alignment slots 56 . Latching hook members 140 are pivoted back over the opening of slots 56 until pins 54 are lodged within notches 142 . With pins 54 locked within hook member notches 142 , and latching member 30 pivoted into position about lower jaw 24 , the stapler is closed and ready to fire staples from the new cartridge.
- the reusable upper and lower jaw and latching member components described above are provided to a user in a non-sterile package.
- the components Prior to assembly of stapler 20 , the components are cleaned with pH neutral enzymatic cleaners, and then steam autoclaved to sterilize the components. This conditioning procedure is also followed prior to each subsequent reuse of the components.
- Actuator module 170 due to it multiple movable components, is designed for single patient use to eliminate the complexity of cleaning the module.
- the actuator module is provided to the user in a sterile disposable package which is opened in the sterile field.
- Staple cartridge 90 is also delivered as a sterile disposable package that is opened in the sterile field.
- actuator module 170 is removed from its packaging and inserted proximal end first into the proximal channel of lower jaw member 24 .
- Actuator module 170 snaps into place when proximal detent bumps 178 engage lower jaw retention features 86 .
- the distal end of the actuator module is then rotated down into the channel shaped frame of lower jaw 24 .
- protector cap 234 is pushed down to snap cap lips 240 into indentations 74 on the lower jaw sidewalls 64 a , 64 b .
- protector cap 234 pushes guide block center section 212 through lower jaw opening 76 , aligning guide block slot 212 with lower jaw slot 82 , and locking the actuator module in place within the lower jaw member 24 .
- latching member 30 With actuator module 170 loaded into lower jaw member 24 , latching member 30 is attached to the lower jaw by inserting latch pin 122 into slots 82 and 212 , as described above. Latching member 30 is rotated relative to lower jaw member 24 to the partial locked-in position shown in FIG. 14 . In this position, latching member 30 is attached to lower jaw member 24 , but upper jaw 22 is separable from the lower jaw.
- Protector cap 234 is removed from actuator module 170 by moving the cap in the distal direction, as indicated by the arrow on the cap shown in the Figures.
- a new staple cartridge 90 is next inserted into lower jaw cartridge channel 70 in the manner described above.
- upper jaw member 22 is placed over lower jaw member 24 , with pins 54 inserted into alignment slots 56 .
- Latching member 30 is pivoted relative to the upper and lower jaw members 22 , 24 to place the stapler into the pre-close position (shown in FIG. 15 ), in which the hook member cam surfaces 144 extend over the openings to alignment slots 56 to prevent pins 54 from disengaging from the slots.
- the tissue to be transected is placed between the anvil 44 and staple cartridge 90 and adjusted to the desired position. Tissue stops 52 prevent the tissue from being positioned too far back into the stapler.
- the stapler With the tissue properly situated, the stapler is closed in preparation for firing by rotating latching member 30 into contact with lower jaw 24 to place hook member 140 over slots 56 , and lock pins 54 inside hook member notches 142 . In this state, the tissue is clamped within the device. If additional tissue adjustment is required, the stapler can be returned to the pre-close state, as shown in FIG. 16 , in which the distal ends of the upper and lower jaw members can move slightly relative to each other to accommodate tissue repositioning. With the tissue properly clamped between the jaw members, and latching member 30 pivoted to the closed, operative position, the stapler can be fired by pushing actuator knob 182 forward through guide slot 186 until the knob stops. As the knob advances, the clamped tissue is stapled and cut.
- actuator knob 182 After actuator knob 182 reaches its distal stop, the knob is drawn back proximally through guide slot 186 . At the proximal end of the knob path, the interaction of detent spring 252 and push block notch 254 provides tactile and audible feedback that the knob is fully retracted, signaling that the actuating components have been withdrawn from staple cartridge 90 back into module pan 172 .
- latching member 30 is pivoted back to the partially locked-in state so that upper jaw 22 can be removed, and the used staple cartridge discarded and replaced with a new staple cartridge. After the new cartridge is in place, latching member 30 can be pivoted back through the pre-close and closed states to enable tissue to again be positioned, clamped and stapled using the new cartridge. Once all the required tissue is transected, latching member 30 is removed by rotating the member back to the open state (shown in FIG. 13 ), and sliding latch pin 122 out of slots 82 and 212 . The actuating module 170 and staple cartridge 90 can then be removed from lower jaw member 24 and discarded. The remaining components (upper jaw, lower jaw, and latching member) can be cleaned and sterilized as separate components in preparation for reuse.
- actuator module 170 is a separate component from staple cartridge 90 , enabling spent staple cartridges to be replaced during a single patient procedure without replacing the actuator module. Accordingly, the actuator module may be used multiple times in the same patient with different staple cartridges.
- the single piece module pan 172 as a supporting structure for the actuator module components enables the actuator module to be easily assembled into and disassembled from the lower jaw channel.
- the reusable stapler components have a simple, single piece design to facilitate repeated reconditioning and reuse of the parts.
- the detachable design of the latching member facilitates easy disassembly and reassembly of the reusable components of the stapler. Further, once the stapler is assembled, the retaining and locking features of the latching and lower jaw members prevent accidental disassembly during a procedure.
Abstract
Description
- The present invention relates generally to surgical stapling instruments and, more particularly, to a surgical stapler which can be disassembled and portions reconditioned and sterilized for reuse in subsequent surgical procedures, and which includes a removable actuating module that can be reused with multiple staple cartridges during a single patient procedure.
- Before surgical staplers were introduced, surgeons had to spend a great deal of time sewing the tissue of patients back together. This was the most time intensive aspect of a surgical procedure. Surgical staplers have decreased the amount of time that a user spends sewing tissue back together. Such surgical staplers are described in the following issued U.S. patents which are hereby incorporated herein by reference: U.S. Pat. No. 4,633,861 Chow et al.; U.S. Pat. No. 4,633,874 Chow et al.; and U.S. Pat. No. 5,129,570 Schulze et al.
- One concern with surgical staplers has been assuring that the staplers used during a procedure are sterile. Reusable staplers have typically been relatively complicated mechanical instruments which are difficult to sterilize after use. Hence, it was once desired that surgical staplers be completely disposable. As more than one surgical stapler may be required in a surgical procedure, for economical reasons disposable surgical staplers having reloadable staple cartridges have been developed. These reloadable staple cartridges have comprised a combination of staples and a firing module for discharging the staples. Typically the cutting instrument is included in the firing module. Therefore, each time a stapler is reloaded with a new staple cartridge, a new knife and firing assembly is also inserted into the stapler. Numerous staple cartridges are normally used during a single patient procedure, resulting in the repeated replacement of the knife and firing elements for the same patient. Since a knife is usually not worn out after a staple cartridge has been emptied, the knife and firing assembly could be reused with additional staple cartridges within the same patient. Reusing the firing assembly within a single patient procedure would not require additional sterilizing and can decrease the costs incurred during the procedure. Recently, there has also been a desire to make portions of a surgical stapler reusable, so that a portion is disposable and a portion is reusable in subsequent procedures. Reusing portions of the stapler reduces the costs associated with surgical procedures, and also decreases the surgical waste.
- Thus, to reduce the costs associated with surgical procedures, there is a need for a surgical stapler that can be disassembled and portions of the stapler reconditioned for subsequent use. In particular, there is a need for a surgical stapler in which the firing and cutting components may be reused with multiple staple cartridges within a single patient procedure in order to decrease the amount of materials utilized with the stapler. There is also a need for a surgical stapler that can be easily assembled and disassembled to allow reconditioning and reuse of some of the stapler parts. In addition, there is a need for a partially reusable stapler that incorporates a disposable firing module to allow the more complex cutting and stapling components to be easily replaced between surgical procedures. Further, there is a need for a partially reusable stapler in which the reusable parts have a simple, one-piece design to facilitate effective reconditioning of the parts between procedures. The present invention provides a partially reusable surgical stapler which achieves these objectives.
- In accordance with the present invention, a partially reusable surgical stapler is provided for deploying staples into tissue. The stapler has a body with a distal end, a proximal end and a longitudinal axis therebetween. The proximal end includes a handle while the distal end includes a staple cartridge holder and an opposing anvil. The stapler also has an actuator module for deploying staples. The actuator module includes at least one longitudinally movable member for sequentially ejecting staples towards the anvil. The actuator module is readily removable and replaceable to and from the body.
- In another embodiment, the present invention provides a partially reusable surgical stapler having an upper jaw member with a proximal handle end and a distal anvil end. A lower jaw member having a proximal channel-shaped frame and a distal staple cartridge channel is aligned with the upper jaw. An actuator module, having at least one longitudinally moveable member for sequentially ejecting staples towards the anvil, is readily removable and replaceable to and from the lower jaw frame. A staple cartridge containing a plurality of staples is removably disposed within the staple cartridge channel. A latching member for connecting the upper and lower jaws together is provided at an intermediate position along a longitudinal axis of the stapler. The latching member is moveable relative to the upper and lower jaw members to place the stapler in a series of different locking states. The different locking states include an assembly state for connecting and disconnecting the latching member to the jaw members, and a closed, latched state in which the latching member is locked to the jaw members.
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FIG. 1 is an isometric view of an exemplary surgical stapler showing the stapler in a closed position; -
FIG. 2 is a front view of the stapler in an open position; -
FIG. 3 is an isometric view of the stapler in an open position; -
FIG. 4 is an isometric bottom view of the reusable upper jaw member for the stapler; -
FIG. 5 is an isometric top view of the stapler upper jaw member; -
FIG. 6 is an isometric view of the reusable lower jaw member including the cartridge channel; -
FIG. 7 is an isometric view of the disposable staple cartridge; -
FIG. 8 is a bottom view of the disposable staple cartridge; -
FIG. 9 is an isometric view of the reusable latching member; -
FIG. 10 is a front view of the reusable latching member; -
FIG. 11 is a detailed isometric view of the distal end of the latching member; -
FIG. 12 is a partial front view of the stapler showing the latching member in a ready to assemble state; -
FIG. 13 is a partial front view of the stapler showing the latching member in an initial inserted state; -
FIG. 14 is a partial front view of the stapler showing the latching member in a rotated and partially locked-in state; -
FIG. 15 is a partial front view of the stapler showing the relative positions of the latching and upper jaw members in a pre-close position; -
FIG. 16 is a partial front view of the stapler showing the relative positions of the latching and upper jaw members in an open position during use; -
FIG. 17 is an isometric view of the disposable actuating module; -
FIG. 18 is another isometric view of the disposable actuating module looking forward from the proximal to the distal end; -
FIG. 19 is an isometric view of the actuating module pan; -
FIG. 20 is a detailed, isometric view of the proximal end of the actuating module; -
FIG. 21 is a top view of the actuating module; -
FIG. 22 is an isometric view of the actuating knob; -
FIG. 23 is an isometric view of the guide block; -
FIG. 24 is an isometric view of a pusher bar; -
FIG. 25 is an isometric view of the knife support bar; -
FIG. 26 is a close-up, isometric view of the distal end of the actuating module showing the protector cap; -
FIG. 27 is a front view of the actuating module; -
FIG. 28 is a sectional view of the actuating module proximal end, showing the relationship between the actuating knob and the detent spring in a full back position; and -
FIG. 29 is a sectional view of the actuating module proximal end, showing the actuating knob moved forward during firing. - Referring now to the drawing figures, in which like numerals indicate like elements throughout the views,
FIGS. 1 through 3 illustrate a first exemplarysurgical stapler 20 of the present invention. The body ofstapler 20 includes anupper jaw member 22, alower jaw member 24, and a latchingmember 30. Latchingmember 30 is pivotable relative to the upper andlower jaws members FIGS. 2-3 . Latchingmember 30 can be pivoted through a series of different latching states to lock the stapler closed for use or to open the stapler varying degrees to allow for adjustment of tissue within the stapler, the replacement of a staple cartridge, or disassembly of the stapler. Upon completion of a surgical procedure, latchingmember 30 can be pivoted to a fully open position to allowstapler 20 to be disassembled in preparation for the resterilization and reuse of portions of the stapler. - As shown in
FIGS. 4 and 5 ,upper jaw 22 comprises a single piece, elongated channel-shaped frame having a pair of opposingsidewalls top wall 36.Top wall 36 is suitably shaped on the outer surface to form a hand grip and includes anupper handle protrusion 40 to facilitate the handling and operation of the stapler by a surgeon. The distal end ofupper jaw 22 comprises a pair of inwardly extendingflanges 42 which define ananvil 44 of the stapler.Flanges 42 are separated by a central,longitudinal slot 46 which extends along the entire length ofanvil 44. The inner surface of eachflange 42 is provided with two longitudinal rows of uniformly spaced staple-formingpockets 50.Staple forming pockets 50 allow the fashioning of B-form staples when U-shaped staples are ejected against the anvil flanges during firing.Anvil 44 includes a tapered tip at the distal-most end for facilitating insertion of the stapler into hollow, tubular body organs. A pair of tissue stops 52 is provided on opposite sides ofanvil 44 adjacent the proximal end of staple forming pockets 50. Tissue stops 52 are laterally aligned with the proximal end ofstaple forming pockets 50 to prevent tissue from being placed into the stapler beyondanvil 44. Blocking tissue at the proximal end ofanvil 44 prevents the pinching or cutting of unstapled tissue. - Cylindrical pins 54 extend from opposite sides of
upper jaw 22 proximal of tissue stops 52.Pins 54 fit inside vertical slots onlower jaw 24 to connect the upper and lower jaws together.Upper jaw 22 also includes a pair ofcurved notches 60 near the proximal end of channel sidewalls 32 a, 32 b.Notches 60 interact withprojections 62 onlower jaw 24, as shown inFIG. 2 , to provide a means for easily aligning the jaws during use.Upper jaw 22 is preferably comprised of a single piece of a biocompatible metal, such as, for example, stainless steel. Using a single piece of material forupper jaw 22 increases the structural integrity of the stapler. Alternatively,upper jaw 22 can be manufactured as two or more separate pieces that are joined together during the manufacturing process by known joining methods such as, for example, welding. - As shown in
FIG. 6 ,lower jaw 24 comprises a single piece, elongated U-shaped frame having a pair ofsidewalls bottom wall 66. At the distal end oflower jaw 24,side walls cartridge channel 70 for supporting a single use staple cartridge within the stapler.Notches 72 are provided insidewalls cartridge channel 70.Notches 72 engage side projections on the staple cartridge to hold the cartridge within the channel.Vertical alignment slots 56 are located proximal ofcartridge channel 70 in the upper edge ofsidewalls upper jaw 22 interface withalignment slots 56 to align and connect the jaw members together. The width between upper jaw sidewalls 32 a, 32 b is slightly greater than the width between lower jaw sidewalls 64 a, 64 b to enable the upper jaw to fit over the lower jaw when pins 54 are inserted intoalignment slots 56, andprojections 62 intonotches 60.Indentations 74 are formed in the outer surface ofsidewalls alignment slots 56.Indentations 74 facilitate the attachment of an actuating module tolower jaw member 24, as will be described in further detail below. - An
opening 76 is formed throughbottom wall 66 at an intermediate position alonglower jaw 24. Sidewalls 64 a, 64 b extend downward on opposite sides of opening 76 to form distally angledprojections 80. Along the distal edge ofprojections 80, sidewalls 64 a, 64 b are shaped to form a straight-sided slot 82 having acircular end 88. The diameter ofcircular end 88 is slightly larger than the width of theslot 82. Proximal ofprojections 80 the outer surfaces ofsidewalls FIG. 6 , the positioning feature can comprise a plurality of detent bumps 84, or other surface indentations, that are machined into the surface of the sidewalls 64 a, 64 b.FIG. 6 shows only a positioning feature on the front side oflower jaw 24, however, it should be understood that the back side of the lower jaw is fashioned in the same manner so that latchingmember 30 may be retained in a series of latching states by both sides of the lower jaw, as will be described below. Aretention feature 86 is formed at the proximal end oflower jaw 24 at the junction betweensidewalls bottom wall 66.Retention feature 86 can comprise an inward expansion ofsidewalls stapler 20. -
FIGS. 7 and 8 show an exemplary removablestaple cartridge 90 for use instapler 20 of the invention.Cartridge 90 is adapted to receive a plurality of surgical staples arranged in at least two laterally spaced longitudinal rows.Cartridge 90 has a body which includes opposite side walls 92 a, 92 b configured to be slidably received in the interior of lowerjaw cartridge channel 70.Staple cartridge 90 is divided longitudinally by a central elongated slot 94 which extends from the proximal end of the cartridge toward its distal end. A plurality of staple openings 96, defined by the cartridge body, are disposed along the elongated center slot 94. In the illustrated embodiment, the staple openings are arranged in two laterally spaced, staggered rows, with each pair of rows disposed on opposite sides of central longitudinal slot 94. The staple openings in adjacent rows are staggered to provide more effective stapling of the tissue when the instrument is operated. Referring toFIG. 8 ,staple cartridge 90 includes a pair of longitudinal slots 100 located on opposite sides of elongated central slot 94 and disposed between the staggered rows of openings 96. Each longitudinal slot 100 extends from the proximal end ofcartridge 90 towards the distal end. A plurality of staple drivers (not shown) are slidably mounted in staple openings 96 for actuating the staples which are loaded intostaple cartridge 90. Each staple driver is designed to simultaneously actuate two staples located in the adjacent rows provided instaple cartridge 90. Thus, a first set of staple drivers is provided for actuating the staples in the staggered rows located on one side of central longitudinal slot 94, and a second set of staple drivers is provided for actuating the staples in the pair of adjacent rows located on the other side of the central longitudinal slot. - The distal end of
staple cartridge 90 includes a tapered tip to facilitate the insertion oflower jaw member 24 into a hollow tubular body organ. Proximal of the tapered tip,staple cartridge 90 is provided with a pair of outwardly extending protrusions 102. A pair of spaced, parallel flanges 104 extends rearward from opposite sides ofstaple cartridge 90. Legs 110 extend downward from flanges 104 at the proximal end of the staple cartridge. Each leg 110 is provided with a rounded, downwardly facing notch 112. Whencartridge 90 is assembled onlower jaw 24, protrusions 102 are loosely received innotches 72 in the lower jaw side walls, and legs 110 extend throughopening 76 in the lowerjaw bottom wall 66. Leg notches 112 engage a pin on latchingmember 30, as will be described below, to hold the cartridge withinlower jaw channel 70. A pair ofwings 114 extends upward and outward from sidewalls 92 a, 92 b at the proximal end ofcartridge 90.Wings 114 function as finger grips which allowstaple cartridge 90 to be manually inserted into and removed fromlower jaw 24. Usingwings 114,cartridge 90 can be lifted out ofjaw opening 76 andnotches 72, to remove the cartridge fromlower jaw 24 following use. Additionally,wings 114 engage lower jaw sidewalls 64 a, 64 b at the proximal end ofcartridge channel 70, as shown inFIG. 3 , to lock the cartridge in place withinlower jaw 24. A short extension 116 is formed at the rear ofcartridge 90 and located between rearwardly projecting legs 110. Central knife slot 94 extends longitudinally through extension 116, which can be provided with inwardly sloped guide surfaces on its opposite sides at the proximal end of the slot. A lock out pin 106 is connected at one end to extension 116 and is pivotable about the connection point. Initially, whenstaple cartridge 90 is loaded intostapler 20, lock out pin 106 extends transversely across central knife slot 94. - As mentioned above,
stapler 20 includes a latchingmember 30 for connecting the upper and lower jaws members together at an intermediate position along the longitudinal length of the stapler. Preferably,jaw members anvil 44 andstaple cartridge 90. In the preferred embodiment, shown inFIG. 9 , latchingmember 30 comprises a single piece, channeled-shaped frame having opposingside walls top wall 130. Latchingmember 30 further includes alatch pin 122 for pivotally connecting the latching member tolower jaw 24. Preferably, the latching member is comprised of a single piece of stainless steel, or another similar biocompatible metal. The distance between the opposing latchingmember side walls sidewalls lower jaw 24.Side walls elongated flanges 132 which serve as finger grips to enable latching arm 120 to be manually pivoted between latching positions. The outer surface of latching arm 120 includes ahandle extension 134. When connected tolower jaw member 24, handleextension 134 combines with upper jaw handleextension 40 to form a hand grip for manipulation of the stapler by a surgeon. - Each
side wall member 30 includes a distally-extending C-shapedhook member 140 provided with a forwardly facingnotch 142 for engaging upper jaw pins 54. As shown inFIGS. 9 and 10 ,hook members 140 include aninner cam surface 144 extending rearward from the tip of the hook member intonotch 142. When latchingmember 30 is moved to a closed, operative state,notches 142 engage upper jaw pins 54, acting as an over-center latch to maintain the latching member in the latched state. Belownotches 142, eachhook member 140 projects distally downward, beyond the end of latching membertop wall 130.Latch pin 122 extends between the down turned ends ofhook members 140, as shown inFIG. 11 , across the end of latchingmember 30.Latch pin 122 has a cylindrical shape withflat surfaces 152 adjacent each end. The diameter oflatch pin 122 is greater than the narrow opening forlower jaw slot 82. Latchingmember 30 is detachably connected tolower jaw 24 by insertinglatch pin 122 intolower jaw slot 82.Latch pin 122 is inserted intoslot 82 by orienting latchingmember 30 so that flat ends 152 lie in parallel with the straight sides of the slot. In this position,latch pin 122 can be inserted intoslot 82 despite the pin diameter being greater than the slot width. With flat ends 152 aligned with the linear sides ofslot 82,latch pin 122 is inserted into the slot, as shown inFIG. 12 , until the pin rests withincircular slot end 88, as shown inFIG. 13 . -
Stapler 20 also includes means for retaining the latching member in a series of different latching states. Referring toFIGS. 9 and 10 , the retaining means includes aspring arm 150 extending from the top edge of eachlatching arm sidewall Spring arm 150 curves distally upward, following the upper contour ofhook member 140, and includes a bulbous free end. With latchingpin 122 assembled withinslot 82, and latchingmember 30 angled distally, as shown inFIG. 13 ,stapler 20 is in an initial, open state. To closestapler 20, latchingmember 30 is rotated towards the proximal end of the stapler, to draw the latching member closer to the body oflower jaw member 24. As flat ends 152 rotate out of alignment with the sides ofslot 82, the difference in width betweenpin 122 andslot 82 prevents the pin from slipping out ofslot end 88.Pin 122 is thus fixed withinslot end 88, locking latchingmember 30 tolower jaw member 24. - As latching
member 30 rotates,hook members 140 are drawn along the sides oflower jaw member 24. Ashook members 140 swing alongside lower jaw sidewalls 64 a, 64 b, the bulbous ends ofspring arms 150 contact detent bumps 84 on the sidewalls. To movespring arms 150 between the detent bumps 84, additional force is applied to latchingmember 30 to cause the spring arms to flex towards thehook members 140, so that the ends of the spring arms can ride over the bumps. Withspring arms 150 positioned between detent bumps 84, as shown inFIG. 14 , latchingmember 30 is in a partially locked-in state. In the partially locked-in state, latchingmember 30 is attached tolower jaw 24 andalignment slots 56 are just distal of the tip ofhook members 140. Upper jaw pins 54 can be freely inserted or removed fromlower jaw slots 56, allowing the upper and lower jaw members to be separated and rejoined together. - As
latch pin 122 continues to rotate withinslot end 88, drawing latchingmember 30 closer tolower jaw member 24, hook member inner cam surfaces 144 rotate over the opening ofalignment slots 56, blocking the slots and locking upper jaw pins 54 within the slots.Spring arms 150 also ride along detent bumps 84 to engage the concave outer edge of the top bump. In this pre-closed state, shown inFIG. 15 , latchingmember 30 and upper andlower jaw members stapler 20, but upper jaw pins 54 can slide withinslots 56, between the bottom of the slot andcam surface 144, to allow some relative movement between the jaw members. Latchingmember 30 maintains the jaw members in a loosely latched position to permit relative movement between the staple cartridge and anvil. The relative movement at the distal end ofjaw members - When latching
member 30 is rotated to a closed, operative state (shown inFIG. 1 ) the latching member surroundslower jaw member 24, and pins 54 onupper jaw member 22 are lodged withinhook member notches 142.Spring arms 150 advance distally upward along the sides oflower jaw member 24 beyond detent bumps 84. In this state, the upper and lower jaw members are locked together to compress tissue between the anvil and cartridge surfaces, and the stapler is ready for stapling and cutting tissue. In the closed state, a minimum spacing may be maintained between the anvil and cartridge surfaces by aspacer pin 160. To adjust the placement of tissue between the anvil and cartridge surfaces, latchingmember 30 can be rotated back to the pre-close state, as shown inFIG. 16 , to dislodgepins 54 fromhook member notches 142. As latchingmember 30 rotates back,spring arms 150 reengage with detent bumps 84 to hold the latching member in place. Returning to the pre-close state loosens the connection betweenhook members 140 and pins 52, to allow the pins to slide withinslots 56 without disconnecting the upper and lower jaws. - To disassemble
stapler 20, latchingmember 30 is rotated away fromlower jaw member 24 to draw upper jaw pins 54 out ofhook notches 142. Latchingmember 30 may be rotated away from upper andlower jaw members latching arm tip 162. As a counter rotating force continues on latching arm 120,spring arms 150 move through detent bumps 84, enablinghook members 140 to swing through and way from the lower jaw sidewalls 64 a, 64 b. Latchingmember 30 is rotated around in the direction ofstaple cartridge 90 until latchingmember 30 returns to the initial, open position shown inFIG. 13 . With latchingmember 30 in the open state, flat ends 152 onlatch pin 122 are again aligned in parallel with the straight sides ofslot 82, enabling the latch pin to be withdrawn throughslot 82 to separate the latching member fromlower jaw member 24. With latchingmember 30 detached,stapler 20 can be disassembled into three separate, one-piece components, namely,upper jaw 22,lower jaw 24 and latchingmember 30. The one-piece channel-shaped construction of these reusable components provides for easy yet thorough reconditioning and sterilization of the components between uses. - Turning now to
FIGS. 17 and 18 , which show anactuator module 170 for stapling and cutting tissue clamped between the upper andlower jaw members Actuator module 170 comprises a U-shaped,longitudinal module pan 172 which provides the supporting structure for the actuator module components.Module pan 172 includes a pair ofsidewalls 174 connected together by a bottom wall 176 (FIG. 19 ). The distance between module pan sidewalls 174 is less than the distance between lower jaw sidewalls 64 a, 64 b to enable the module pan to be slidably mounted within the proximal channel oflower jaw 24. As shown inFIGS. 19 and 20 , the proximal end ofmodule pan 170 includes one or more detent bumps 178 protruding from the outer surface ofsidewalls 174. Detent bumps 178 engage retention features 86 on the inside channel oflower jaw member 24 when theactuator module 170 is slid proximally into the lower jaw channel. The interaction of detent bumps 178 with retention features 86 snaps and retains the actuator module in place withinlower jaw member 24. - As shown in
FIG. 21 , a plurality of moveable actuating members are situated withinmodule pan 172 for longitudinal movement within the pan relative to upper andlower jaw members pusher block 180 which is disposed withinmodule pan 172 for reciprocal, longitudinal movement within the pan.Pusher block 180 is attached to anactuator knob 182 by alateral flange 184. Whenactuator module 170 is mounted withinlower jaw 24, as shown inFIG. 3 ,flange 184 extends through anelongated guide slot 186 formed in a sidewall 64 of the lower jaw.Flange 184positions knob 182 on the outside ofjaw members FIG. 3 ,knob 182 is shown extending through aguide slot 186 inlower jaw sidewall 64 b. However, a guide slot could also be formed in the oppositelower jaw sidewall 64 a, in whichcase actuating knob 182 would extend out the opposite side ofstapler 20.Flange 184 extends through and rides alongguide slot 186 asknob 182 is manually moved along the outside ofjaw members - Returning now to
FIG. 21 ,actuator module 170 also includes a pair of longitudinally extending, parallel pusher bars 190. The proximal ends of pusher bars 190 are secured within laterally spaced pusher block slots 192 (shown inFIG. 22 ) to allow the pusher bars to move longitudinally withpusher block 180 throughmodule pan 172. Pusher bars 190 extend distally frompusher block 180 and are slidably received inlongitudinal slots 194 formed in aguide block 200, shown inFIG. 23 . As shown inFIG. 18 ,guide block 200 is mounted at the distal end ofmodule pan 172. The upper edges of module pan sidewalls 174 are bent inward over the side edges ofguide block 200 to retain the guide block within the module pan. Additionally,tabs 202 extend from the sides ofguide block 200 throughopenings 204 in module pan sidewalls 174 to secure the guide block within the pan. The distal end ofguide block 200 extends beyond the end ofmodule pan 172 and between rear flanges 104 ofstaple cartridge 90.Lateral slots 194 withinguide block 200align pusher bars 190 with the elongated staple driver slots 100 ofstaple cartridge 90. The distal ends of pusher bars 190 extend forward ofguide slots 194 and are provided with a wedge-shapedtip 206, shown inFIG. 24 , which defines an inclined cam surface for engaging the staple drivers withincartridge 90 as the pusher bars are moved distally through the cartridge. The longitudinal movement of thepusher bar tips 206 sequentially drives the staple drivers, through a camming action, to fire staplers from the cartridge. - Returning to
FIG. 23 ,guide block 200 includes a dependingcenter section 210 which extends downward throughopening 76 in the lowerjaw bottom wall 66.Center section 210 includes a distally angled, straight-sided slot 212 with acircular end 218. Whenstapler 20 is assembled,guide block slot 212 is longitudinally aligned withslot 82 in lower jaw sidewalls 64 a, 64 b to enablelatch pin 122 to engage bothlower jaw 24 and guide block 200 when latchingmember 30 is connected to the stapler. Aslatch pin 122 is inserted throughslot 82 intoslot end 88, the pin also passes throughguide block slot 212 and lodges withincircular end 218, locking theactuator module 170 andlower jaw 24 together. - As shown in
FIGS. 18 and 21 ,actuator module 170 further comprises aknife support bar 214 positioned between pusher bars 190.Knife support bar 214 andpusher bars 190 are preferably manufactured as sheet metal components. The proximal end ofknife support bar 214 is secured within acenter slot 216 of pusher block 180 (FIG. 22 ) to connect the knife support bar to the pusher block for movement by firingknob 182. Distal ofpusher block 180,knife support bar 214 is slidably received in acenter slot 220 formed in guide block 200 (shown inFIG. 23 ) to align the knife support bar with the elongated center slot 94 of the staple cartridge. As shown inFIG. 25 , aninclined knife blade 222 having a beveled cutting edge is located at the front end ofknife support bar 214. The beveled cutting edge ofknife blade 222 is oriented at an angle relative tojaw members longitudinal slot 220 ofguide block 200. Proximal ofknife blade 222,knife support bar 214 includes acartridge locking notch 228 and a locking cut outsection 224, which are part of a safety lockout mechanism described below. The proximal end ofknife support bar 214 includes an offset section, indicated byreference number 226. Knife offset 226 is formed by cutting away a section of theknife support bar 214 near the proximal end, to produce twoelevated points - As shown in
FIGS. 26 and 27 , aprotector cap 234 covers the distal end ofguide block 200. Acenter section 236 ofcap 234 surroundsknife blade 222 and the wedgedtips 206 of pusher bars 190. An inwardly directedlip 240 extends along the bottom edge of the cap. During assembly, downward pressure is applied toprotector cap 234 to snap the distal end of the actuator module in place inside the lower jaw channel. Ascap 234 is pressed downward,cap lip 240 snaps intoindentations 74 on the outer surface oflower jaw 24. - A
leaf spring 250, shown inFIG. 19 , is integrated into module panbottom wall 176 beneathguide block 200.Spring 250 provides a safety lockout feature by lifting knife support bar cut out 224 againstguide block 200 after firing, to prevent re-firing of a used cartridge. Asecond spring 252 is integrated into module panbottom wall 176 near the proximal end of the pan. Thissecond spring 252 is a detent spring that interacts with a notch onpusher block 180 to prevent forward movement ofactuator knob 182 during shipping, and to provide audible and tactile feedback when the actuator knob is returned to the proximal-most position in the module pan following firing.FIGS. 28 and 29 illustrate the operation ofdetent spring 252 in greater detail. InFIG. 28 ,spring 252 is shown engaging anotch 254 onpusher block 180 to prevent unintentional distal movement of the pusher block.FIG. 29 shows detent spring 252 disengaged fromnotch 254 by the application of an intentional, distally directed force onactuator knob 182. Pusher bars 190 andknife support bar 214 are advanced distally by applying sufficient force toactuator knob 182 to overcome the force ofspring 252 againstnotch 254. Afterspring 252 is disengaged fromnotch 254, pusher block 180 can slide distally throughmodule pan 172 to first advance pusher bars 190 and then advanceknife support bar 214 fromguide block 200 intostaple cartridge 90. - In an initial firing position, shown in
FIG. 28 , a downwardly directed edge ofpusher block 180 is in contact withknife support bar 214 at theproximal end point 232 of offsetsection 226.Actuating knob 182 is retracted to a fully proximal position withinguide slot 186, thereby placingpusher bars 190 andknife blade 222 withinslots guide block 200. When a distal pushing force is applied to actuatingknob 182,spring 252 disengages fromnotch 254, enabling pusher block 180 to advance longitudinally withinmodule pan 172. Aspusher block 180 moves, the block advances pusher bars 190 distally, causing the inclined tips of the bars to advance into cartridge driver slots 100. During the initial movement ofpusher block 180, the distal edge of the block moves through knife support bar offset 226, as shown inFIG. 29 , thereby not making contact with the support bar itself.Knife support bar 214 thus remains stationary during the initial distal movement of the pusher bars 190 and block 180. - After pusher block 180 advances through knife offset
section 226, the distal edge of the block contacts thedistal end point 230 ofknife support bar 214. This contact betweenpusher block 180 andknife support bar 214 causes the knife support bar to begin advancing distally, along with the pusher block andpusher bars 190, asknob 182 is advanced. Asknife support bar 214 moves distally,knife blade 222 is guided bycentral slot 220 and rear cartridge extension 116 into central longitudinal slot 94 ofstaple cartridge 90 and centrallongitudinal slot 46 ofanvil 44. Asknife blade 222 advances through cartridge extension 116, the blade deflects lock out pin 106 out of the path of the advancing support bar.Knife blade 222 andpusher bar tips 206 advance simultaneously throughstaple cartridge 90 driving staples through openings 96 and cutting tissue.Knife blade 222 is advanced intostaple cartridge 90 slightly behind pusher bars 190 so that staples are formed into the tissue gripped between the anvil and cartridge prior to the knife blade advancing and cutting the tissue between the staple rows. - After the knife and pusher bars have been fully advanced by knob 182 (or advanced to the desired forward position), pusher block 180 is retracted within
module pan 172 by drawing the actuating knob back proximally throughjaw guide slot 186. Initially, aspusher block 180 is drawn proximally, pusher bars 190 are drawn proximally whileknife support bar 214 remains in a distal, stationary position due to the offsetsection 226 in the support bar. As the distal pusher block edge retracts into contact with proximal knife bar offsetpoint 232, theknife support bar 214 begins to retract proximally with the pusher block and bars. Asknife support bar 214 retracts withinguide block 200, the support bar is lifted up byleaf spring 250 into contact with the guide block, until the knife locking cut out 224 catches a center post 256 (FIG. 23 ) of the guide block. Once knife cut out 224 engagesguide block post 256,knife support bar 214 is prevented from further movement in conjunction withpusher block 180. Preferably,knife support bar 214 engages locking cut outsection 224 aspusher block 180 andpusher bars 190 are reaching the fully proximal position. - After
actuator knob 182 is fully retracted, as shown inFIG. 28 , latchingmember 30 is pivoted relative tojaw members staple cartridge 90 can be removed and replaced with a new cartridge. The used cartridge can be removed by pulling up oncartridge wings 114 to dislodge cartridge legs 110 fromlower jaw opening 76. As the proximal end of the staple cartridge is lifted out oflower jaw opening 76, cartridge leg notches 112 (FIG. 7 ) are drawn out of engagement withlatch pin 122. After the proximal end ofstaple cartridge 90 is dislodged, the cartridge can be slid distally out ofcartridge channel 70 and discarded. - A
new staple cartridge 90 can be loaded intolower jaw 24 by pushing the flanged, distal end of the cartridge against the distal end of the lowerjaw cartridge channel 70, and pushing down onwings 114 to lower legs 110 throughjaw opening 76. Cartridge legs 110 are pushed throughlower jaw opening 76 until leg notches 112 snap ontolatch pin 122. As the proximal end ofstaple cartridge 90 is pushed down, lockout pin 106 on the cartridge depressesknife support bar 214 at lockingnotch 228 against the counter force ofleaf spring 250. The force of lockout pin 106 pushes knifesupport bar cutout 224 down and out of contact with guideblock center post 256. Asknife support bar 214 is pushed down, the support bar is realigned with guideblock center slot 220 to enable the support bar to pass distally through the slot and into the new cartridge. The safety lockout feature is thus reset during loading of a new staple cartridge. With a new cartridge loaded, the stapler can be reassembled by placingupper jaw 22 overlower jaw 24 and reinserting upper jaw pins 54 into lowerjaw alignment slots 56. Latchinghook members 140 are pivoted back over the opening ofslots 56 untilpins 54 are lodged withinnotches 142. Withpins 54 locked withinhook member notches 142, and latchingmember 30 pivoted into position aboutlower jaw 24, the stapler is closed and ready to fire staples from the new cartridge. - The reusable upper and lower jaw and latching member components described above are provided to a user in a non-sterile package. Prior to assembly of
stapler 20, the components are cleaned with pH neutral enzymatic cleaners, and then steam autoclaved to sterilize the components. This conditioning procedure is also followed prior to each subsequent reuse of the components.Actuator module 170, due to it multiple movable components, is designed for single patient use to eliminate the complexity of cleaning the module. The actuator module is provided to the user in a sterile disposable package which is opened in the sterile field.Staple cartridge 90 is also delivered as a sterile disposable package that is opened in the sterile field. - To assemble
stapler 20,actuator module 170 is removed from its packaging and inserted proximal end first into the proximal channel oflower jaw member 24.Actuator module 170 snaps into place when proximal detent bumps 178 engage lower jaw retention features 86. The distal end of the actuator module is then rotated down into the channel shaped frame oflower jaw 24. Withactuator module 170 within the lower jaw channel,protector cap 234 is pushed down to snapcap lips 240 intoindentations 74 on the lower jaw sidewalls 64 a, 64 b. Pushing down onprotector cap 234 pushes guideblock center section 212 throughlower jaw opening 76, aligningguide block slot 212 withlower jaw slot 82, and locking the actuator module in place within thelower jaw member 24. Withactuator module 170 loaded intolower jaw member 24, latchingmember 30 is attached to the lower jaw by insertinglatch pin 122 intoslots member 30 is rotated relative tolower jaw member 24 to the partial locked-in position shown inFIG. 14 . In this position, latchingmember 30 is attached tolower jaw member 24, butupper jaw 22 is separable from the lower jaw.Protector cap 234 is removed fromactuator module 170 by moving the cap in the distal direction, as indicated by the arrow on the cap shown in the Figures. - A
new staple cartridge 90 is next inserted into lowerjaw cartridge channel 70 in the manner described above. After a staple cartridge is loaded,upper jaw member 22 is placed overlower jaw member 24, withpins 54 inserted intoalignment slots 56. Latchingmember 30 is pivoted relative to the upper andlower jaw members FIG. 15 ), in which the hook member cam surfaces 144 extend over the openings toalignment slots 56 to preventpins 54 from disengaging from the slots. The tissue to be transected is placed between theanvil 44 andstaple cartridge 90 and adjusted to the desired position. Tissue stops 52 prevent the tissue from being positioned too far back into the stapler. With the tissue properly situated, the stapler is closed in preparation for firing by rotating latchingmember 30 into contact withlower jaw 24 to placehook member 140 overslots 56, and lockpins 54 insidehook member notches 142. In this state, the tissue is clamped within the device. If additional tissue adjustment is required, the stapler can be returned to the pre-close state, as shown inFIG. 16 , in which the distal ends of the upper and lower jaw members can move slightly relative to each other to accommodate tissue repositioning. With the tissue properly clamped between the jaw members, and latchingmember 30 pivoted to the closed, operative position, the stapler can be fired by pushingactuator knob 182 forward throughguide slot 186 until the knob stops. As the knob advances, the clamped tissue is stapled and cut. Afteractuator knob 182 reaches its distal stop, the knob is drawn back proximally throughguide slot 186. At the proximal end of the knob path, the interaction ofdetent spring 252 and pushblock notch 254 provides tactile and audible feedback that the knob is fully retracted, signaling that the actuating components have been withdrawn fromstaple cartridge 90 back intomodule pan 172. - If additional stapling and cutting is desired to complete the procedure, latching
member 30 is pivoted back to the partially locked-in state so thatupper jaw 22 can be removed, and the used staple cartridge discarded and replaced with a new staple cartridge. After the new cartridge is in place, latchingmember 30 can be pivoted back through the pre-close and closed states to enable tissue to again be positioned, clamped and stapled using the new cartridge. Once all the required tissue is transected, latchingmember 30 is removed by rotating the member back to the open state (shown inFIG. 13 ), and slidinglatch pin 122 out ofslots actuating module 170 andstaple cartridge 90 can then be removed fromlower jaw member 24 and discarded. The remaining components (upper jaw, lower jaw, and latching member) can be cleaned and sterilized as separate components in preparation for reuse. - In the present invention,
actuator module 170 is a separate component fromstaple cartridge 90, enabling spent staple cartridges to be replaced during a single patient procedure without replacing the actuator module. Accordingly, the actuator module may be used multiple times in the same patient with different staple cartridges. Using the singlepiece module pan 172 as a supporting structure for the actuator module components enables the actuator module to be easily assembled into and disassembled from the lower jaw channel. The reusable stapler components have a simple, single piece design to facilitate repeated reconditioning and reuse of the parts. The detachable design of the latching member facilitates easy disassembly and reassembly of the reusable components of the stapler. Further, once the stapler is assembled, the retaining and locking features of the latching and lower jaw members prevent accidental disassembly during a procedure. - The foregoing description of a preferred embodiment of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise form disclosed. Obvious modifications or variations are possible in light of the above teachings. The embodiment was chosen and described in order to best illustrate the principles of the invention and its practical application to thereby enable one of ordinary skill in the art to best utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims appended hereto.
Claims (21)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
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US12/137,576 US8007513B2 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
US12/137,571 US20090308907A1 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
AU2009257442A AU2009257442B2 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
AU2009257417A AU2009257417B2 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
CA2726527A CA2726527A1 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
CA2726523A CA2726523C (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
CN200980121940.3A CN102088916B (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
PCT/US2009/047043 WO2009152333A1 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
EP09763597.3A EP2299914B1 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
JP2011513683A JP5512663B2 (en) | 2008-06-12 | 2009-06-11 | Partially reusable surgical stapler |
RU2011100173/14A RU2500360C2 (en) | 2008-06-12 | 2009-06-11 | Surgical apparatus for application of staples with reusable components |
CN200980121944.1A CN102056553B (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
BRPI0915375A BRPI0915375B8 (en) | 2008-06-12 | 2009-06-11 | surgical stapler for installing staples in fabrics |
PCT/US2009/047009 WO2009152307A1 (en) | 2008-06-12 | 2009-06-11 | A partially reusable surgical stapler |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US12/137,571 US20090308907A1 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
US12/137,576 US8007513B2 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
Publications (1)
Publication Number | Publication Date |
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US20090308907A1 true US20090308907A1 (en) | 2009-12-17 |
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US12/137,571 Abandoned US20090308907A1 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
US12/137,576 Expired - Fee Related US8007513B2 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
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Application Number | Title | Priority Date | Filing Date |
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US12/137,576 Expired - Fee Related US8007513B2 (en) | 2008-06-12 | 2008-06-12 | Partially reusable surgical stapler |
Country Status (6)
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US (2) | US20090308907A1 (en) |
EP (1) | EP2299914B1 (en) |
CN (2) | CN102056553B (en) |
AU (2) | AU2009257417B2 (en) |
CA (2) | CA2726527A1 (en) |
WO (2) | WO2009152307A1 (en) |
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Also Published As
Publication number | Publication date |
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AU2009257417B2 (en) | 2014-05-08 |
CN102056553A (en) | 2011-05-11 |
CN102088916A (en) | 2011-06-08 |
WO2009152333A1 (en) | 2009-12-17 |
EP2299914B1 (en) | 2014-03-19 |
CN102088916B (en) | 2014-03-26 |
CA2726523C (en) | 2016-10-11 |
CN102056553B (en) | 2014-05-28 |
WO2009152307A1 (en) | 2009-12-17 |
AU2009257442B2 (en) | 2013-10-10 |
US8007513B2 (en) | 2011-08-30 |
US20090308909A1 (en) | 2009-12-17 |
CA2726523A1 (en) | 2009-12-17 |
AU2009257442A1 (en) | 2009-12-17 |
CA2726527A1 (en) | 2009-12-17 |
EP2299914A1 (en) | 2011-03-30 |
AU2009257417A1 (en) | 2009-12-17 |
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