US20120019110A1 - Biosafety cabinetry - Google Patents
Biosafety cabinetry Download PDFInfo
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- US20120019110A1 US20120019110A1 US13/186,807 US201113186807A US2012019110A1 US 20120019110 A1 US20120019110 A1 US 20120019110A1 US 201113186807 A US201113186807 A US 201113186807A US 2012019110 A1 US2012019110 A1 US 2012019110A1
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- United States
- Prior art keywords
- workspace
- biosafety cabinet
- glove
- differential pressure
- pressure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J21/00—Chambers provided with manipulation devices
- B25J21/02—Glove-boxes, i.e. chambers in which manipulations are performed by the human hands in gloves built into the chamber walls; Gloves therefor
Definitions
- the present invention relates to draft chambers, class II biohazard safety cabinets, and chemical hazard safety cabinets (may hereinafter be referred to collectively as “biosafety cabinets”) and, more particularly, to a biosafety cabinet suitable for use in handling contaminants in a workspace formed therein.
- a cabinet having such a workspace includes a front shutter and a front opening formed below the front shutter.
- An operator can extend his/her arms through the front opening into the cabinet and handle, for example, nanomaterial or chemically contaminated material.
- a flow of inward air being sucked into the cabinet or an air barrier is formed in the front opening.
- HEPA particulate air
- biosafety cabinet When an existing type of biosafety cabinet as described above is used, an operator extends his/her arms through glove insertion ports formed in the front of a workspace and handles contaminants placed on a work surface disposed in the workspace.
- the positions of the gloves worn by the operator are fixed, so that there are cases in which the location in the workspace where the material to be handled can be placed is restricted or in which the operator's performance is restricted depending on his/her body type.
- the glove positions are fixed as a result of attaching importance to the air-tightness of the biosafety cabinet.
- the biosafety cabinet incorporates strict measures against chemical contamination and biohazards.
- the present invention has been made in view of the above problem, and it is an object of the present invention to improve the workability of operation to be performed, while preventing chemical or biological contamination, using a biosafety cabinet and gloves attached to the cabinet. Another object of the present invention is to improve the workability of operation to be performed, while taking measures against biohazards and chemical hazards, using a biosafety cabinet and gloves attached to the cabinet.
- the present invention provides a biosafety cabinet comprising an air exhaust unit for discharging air in a workspace formed in a main body cabinet to outside via a filter, a front shutter vertically movably installed on a front of the workspace, and a front opening formed below the front shutter at a front of the workspace.
- the front shutter is provided with a plurality of small windows which are laterally movable and which are overlapped like layered sliding doors.
- One of the plurality of small windows is provided, on the workspace side thereof, with a pair of glove ports to which a pair of gloves for use in operation in the workspace can be air-tightly attached.
- the biosafety cabinet according to the present invention may be configured such that only one of the plurality of small windows is attached with a pair of the gloves or such that two of the plurality of small windows are each attached with one of the gloves.
- a holding groove may be provided on each lateral side of the front opening, the holding groove being for removably holding a corresponding lateral end portion of a laterally outermost one of the plurality of small windows on each side.
- the biosafety cabinet preferably further comprises a differential pressure sensor for detecting a differential pressure between a pressure in the workspace and a pressure outside the biosafety cabinet or between the pressure in the workspace and a pressure at downstream of the filter and a control unit for controlling an output of the exhaust unit according to a differential pressure signal inputted from the differential pressure sensor.
- the biosafety cabinet may further comprise a glove panel removably installed in the front opening to be below the front shutter, the glove panel being attached with a glove.
- a biosafety cabinet has gloves movably attached to a front cover thereof, so that the workability of operation to be performed, while preventing chemical contamination or biological contamination, using the gloves can be improved. Also, the workability of operation to be performed, while taking measures against biohazards or chemical hazards, using the gloves attached to the biosafety cabinet can be improved.
- FIGS. 1A and 1B show a chemical hazard safety cabinet according to an embodiment (a first embodiment) of the present invention, FIG. 1A being a longitudinal sectional view and FIG. 1B being a front view.
- FIGS. 2A and 2B show the cabinet shown in FIGS. 1A and 1B in a state with a front shutter thereof closed, FIG. 2A being a longitudinal sectional view and FIG. 2B being a front view.
- FIGS. 3A and 3B show the cabinet shown in FIGS. 1A and 1B in a state with gloves moved left, FIG. 3A being a longitudinal sectional view and FIG. 3B being a front view.
- FIG. 4 is a front view of the cabinet shown in FIGS. 1A and 1B with the gloves moved right.
- FIGS. 5A to 5D show the front shutter of the cabinet shown in FIGS. 1A and 1B , FIGS. 5A and 5B being horizontal sectional views and FIGS. 5C and 5D being partial horizontal sectional views.
- FIGS. 6A and 6B show a chemical hazard safety cabinet according to another embodiment (a second embodiment) of the present invention, FIG. 6A being a longitudinal sectional view and FIG. 6B being a front view.
- FIG. 7 is a horizontal sectional view of the front shutter of the cabinet shown in FIGS. 6A and 6B .
- FIGS. 8A and 8B show a chemical hazard safety cabinet according to still another embodiment (a third embodiment) of the present invention, FIG. 8A being a longitudinal sectional view and FIG. 8B being a front view.
- FIG. 9 is a horizontal sectional view of the front shutter of the cabinet shown in FIGS. 8A and 8B .
- FIGS. 10A and 10B show a chemical hazard safety cabinet according to still another embodiment (a fourth embodiment) of the present invention, FIG. 10A being a longitudinal sectional view and FIG. 10B being a front view.
- FIG. 11 is a diagram for describing air flow rate control performed in the cabinet shown in FIGS. 10A and 10B .
- FIGS. 1A and 1B show a chemical hazard safety cabinet 1 , FIG. 1A being a longitudinal sectional view and FIG. 1B being a front view.
- the cabinet 1 has a front shutter 4 vertically movably installed on a front of a workspace 3 formed inside a main body case 1 a .
- a front opening 6 of the workspace 3 appears below the front shutter 4 .
- the front shutter 4 is in a lowered position, the front opening 6 is closed.
- a HEPA filter path 12 a is formed in upper and lower portions, behind the workspace 3 , of the interior of the main body case 1 a .
- the HEPA filter path 12 a is used to filter contaminants and dust generated in the workspace 3 for air purification.
- a plastic bag 15 for accommodating the contaminated HEPA filter 12 is held in an upper portion of space behind the workspace 3 .
- a space 12 b on the downstream side of the HEPA filter 12 is a clean space separated from the workspace 3 by a HEPA filter cover 13 .
- the HEPA filter cover 13 is fitted with a packing 14 for enhanced sealing.
- a wire mesh is installed in a lower back side of the workspace 3 to prevent the operator's hands from entering the HEPA filter path 12 a .
- a prefilter 11 and the HEPA filter 12 are disposed with the latter being above the former.
- a blower 5 is attached upward of the HEPA filter 12 .
- An exhaust port 8 is formed in the main body case la to be on the outlet side of the blower 5 .
- the bottom of the workspace 3 is used as a work surface 2 .
- the inward air flow 7 enters the workspace 3 and is sucked in to pass the prefilter 11 to have contaminants 10 contained in the air removed by the HEPA filter 12 .
- the HEPA-filtered air is then sucked in by the blower 5 to be discharged as exhaust air 9 through the exhaust port 9 formed in the main body case 1 a .
- the operator not shown, extends his/her arms into the workspace 3 through the front opening 6 and handles the contaminants 10 , i.e. samples, in the workspace 3 .
- the inward air flow 6 formed at the front opening 6 prevents the contaminants 10 generated in or brought into the workspace 3 from leaking out of the cabinet 1 .
- the front shutter 4 has small windows 18 a to 18 c formed therein.
- the small windows 18 a to 18 c are horizontally movable in the front shutter 4 . They are made of a transparent material, for example, glass, so that the interior of the workspace 3 can be seen from outside the cabinet 1 .
- the inward air flow 7 to be sucked into the cabinet 1 is formed at the front opening 6 making the pressure inside the workspace 3 negative ( ⁇ ). With the inward air flow 7 formed, when the operator extends his/her arms through the front opening 6 to handle the contaminants 10 in the workspace 3 , neither the contaminants 10 are inhaled by the operator nor they leak out of the cabinet 1 .
- the contaminants 10 handled in the workspace 3 are removed by the prefilter 11 and the HEPA filter 12 , allowing only clean air to be discharged from the exhaust port 8 . This causes the contaminants 10 to be accumulated at the HEPA filter 12 . Eventually, the HEPA filter 12 is clogged and becomes unable to satisfactorily pass air. When this occurs, it is necessary to replace the HEPA filter 12 .
- HEPA filter 12 To remove the HEPA filter 12 , remove the HEPA filter cover 13 provided on the workspace 3 side of the plastic bag 15 that is disposed on the front side of the HEPA filter 12 , then take out the HEPA filter 12 holding it via the plastic bag 15 while covering the HEPA filter 12 with the plastic bag 15 .
- FIGS. 2A and 2B show the chemical hazard safety cabinet 1 shown in FIGS. 1A and 1B in a state with the front shutter 4 closed, FIG. 2A being a longitudinal sectional view and FIG. 2B being a front view.
- FIGS. 1A and 1B show the front opening 6 in a state with the front shutter 4 closed
- FIG. 2A being a longitudinal sectional view
- FIG. 2B being a front view.
- the front opening 6 is open, the operator can extend his/her arms into the workspace 3 through the front opening 6 and handle the contaminants 10 with the inward air flow 7 preventing the contaminants 10 from leaking out.
- the front shutter 4 is closed as shown in FIGS. 2A and 2B .
- the small transparent windows 18 a to 18 c provided in the front shutter 4 are horizontally movable in the front shutter 4 .
- the small window 18 a includes glove ports 17 to which gloves 16 are air-tightly attached, so that the operator can handle the contaminants 10 in the workspace 3 via the gloves 16 .
- the inward air flow 7 sucked in by the blower 5 enters the workspace 3 through the clearance between the front shutter 4 and the main case 1 a making the pressure inside the workspace 3 negative.
- FIGS. 3A and 3B show the cabinet 1 in a state in which the front shutter 4 is closed and the small window 18 a including the glove ports 17 has been moved to the left to allow the small windows 18 b and 18 c on the right side to be used.
- FIG. 3A and 3B show the cabinet 1 in a state in which the front shutter 4 is closed and the small window 18 a including the glove ports 17 has been moved to the left to allow the small windows 18 b and 18 c on the right side to be used.
- FIG. 4 shows the cabinet 4 in a state in which the small window 18 a including the glove ports 17 has been moved to the right to allow the small windows 18 b and 18 c on the left side to be used.
- FIGS. 3A and 3B FIGS. 3A and 3B , FIG. 3A is a longitudinal sectional view and FIG. 3B is a front view.
- the gloves 16 are positioned in a lateral center portion of the front shutter 4 , so that there can be cases where the operator cannot reach a side of the workspace 3 .
- the horizontally movable, transparent small window 18 a provided in the front shutter 4 is moved to the right or to the left as shown in FIG. 3B or as shown in FIG. 4 .
- FIGS. 5A to 5D are sectional views taken along line A-A in FIG. 2B , showing how the small windows 18 a to 18 c are moved and positioned.
- the small window 18 a is shown in a lateral center position.
- the small window 18 a is shown moved to the right side.
- FIG. 5C is a detailed view of portion C of FIG. 5B .
- FIG. 5D is a detailed view of portion D of FIG. 5B .
- the transparent small window 18 a has two circular glove ports 17 air-tightly attached thereto.
- the glove ports 17 can each be attached with an air-tight glove 16 .
- the small window 18 a is made of a transparent plate, for example, a glass plate and is fitted with rectangular small-window frames 19 being described later.
- the small windows 18 b are disposed, each being like one of layered sliding doors made of glass, on both sides of the small window 18 a .
- the small windows 18 c are disposed, also each being like one of layered sliding doors made of glass, on the lateral outer sides of the small windows 18 b.
- the small window 18 a and the right small window 18 b , and the right small window 18 c are overlapped in the front-to-rear direction.
- the left small window 18 b is also moved rightward, but the left small window 18 c , the left small window 18 b , and the small window 18 a remain connected by small-window frames 19 , being described in the following, fitted to their lateral end portions.
- the small windows 18 a to 18 c are, as described above, plate members, and the left and right sides of each of the small windows 18 a to 18 c are each fitted with a rectangular small-window frame 19 .
- the small-window frames 19 fitted to the small windows 18 b positioned between the small window 18 a and the small windows 18 c partly differ in shape from the small-window frames 19 fitted to the small windows 18 a and 18 c .
- the outer small-window frame 19 has two projections 19 a each having a rectangular cross-section.
- the inner small-window frame 19 has only one projection 19 a formed in a lateral inner end portion on the front side thereof.
- the small window 18 a On the right side of the small window 18 a , as the small window 18 a is moved rightward, the right small-window frame 19 fitted thereto comes to hit the front projection 19 a of the right small-window frame 19 fitted to the right small window 18 b to cause the right small window 18 b to also move rightward.
- the small window 18 a eventually reaches its rightmost position, the small windows 18 a to 18 c are overlapped in the front-rear direction as shown in FIG. 5D .
- the gloves 16 can be easily moved horizontally, whether to left or right. This increases the degree of freedom of operation to be performed using the gloves 16 .
- FIGS. 6A and 6B show a chemical hazard safety cabinet 1 , FIG. 6A being a longitudinal sectional view and FIG. 6B being a front view.
- FIG. 7 is a sectional view, taken along line E-E in FIG. 6B , of a front shutter 4 included in the cabinet 1 shown in FIGS. 6A and 6B .
- the second embodiment differs from the first embodiment in that a front opening 6 is provided with a glove panel 20 . Excepting this difference, the configuration of the second embodiment is the same as that of the first embodiment.
- a grooved holding member 22 is provided on each side of the front opening 6 .
- the glove panel 20 is held, at both sides thereof, by the grooved holding members 22 .
- the grooved holding members 22 are positioned inwardly of the front shutter 4 , i.e. to be more inside a workspace 3 than the front shutter 4 .
- the glove panel 20 is installed in position by being inserted, from above, into the grooves of the grooved holding members 22 .
- the glove panel 20 is installed on the workspace 3 side of the front shutter 4 .
- the front shutter 4 can be lifted and lowered in a range where the gloves 16 attached to the front shutter 4 are not hit.
- the above configuration will be effective, for example, in cases where, with the front shutter 4 completely lowered, the glove ports 17 of the front shutter 4 are positioned too low to allow the operator to conveniently use the gloves 16 attached to the glove ports 17 . Even in cases where: the vertical positions of the gloves 16 attached to the front shutter 4 are appropriately adjusted; the front opening 6 is formed below the front shutter 4 ; and the gloves 16 are used by the operator in handling the contaminants 10 ; the air barrier effect of an inward air flow 7 alone might be inadequate to prevent the contaminants 10 from leaking out. In such cases, too, the above configuration can be effective.
- the cabinet 1 has gloves 16 in two levels, i.e. the upper gloves 16 attached to the front shutter 4 and the lower gloves 16 attached to the glove panel 20 , any combination of which can be selected by the operator depending on the type of operation to be performed or his/her body type. Also, with the plural gloves 16 provided, plural operators can simultaneously participate in operation to be performed in the workspace 3 .
- the inward air flow 7 is used as an air barrier to separate the workspace 3 and the outside space, the inward air flow 7 is blocked when plural operators stand in front of the front opening 6 .
- the air barrier effect of the inward air flow 7 is lost possibly allowing the contaminants 10 to leak out from the workspace 3 .
- the glove panel 20 is installed to separate the workspace 3 from the outside space, so that the contaminants 10 in the workspace 3 are prevented from leaking out even when plural operators stand in front of the cabinet 1 .
- the glove panel 20 is provided on the workspace 3 side of the front shutter 4 , the same effect can be obtained also by providing the glove panel 20 in front of the front shutter 4 .
- FIGS. 8A and 8B show a chemical hazard safety cabinet 1 , FIG. 8A being a longitudinal sectional view and FIG. 8B being a front view.
- FIG. 9 is a sectional view, taken along line F-F in FIG. 8B , of a front shutter 4 included in the cabinet 1 shown in FIGS. 8A and 8B .
- the third embodiment differs from the first embodiment in that glove ports 17 are provided not in a central small window 18 a but in left and right small windows 18 b . No glove port is provided in the small window 18 a .
- the central small window 18 a is positioned between the left and right small windows 18 b . Distance G between the two gloves 16 can be changed.
- the small window 18 a and the small windows 18 b are arranged to be partly overlapped.
- the small windows 18 b and the small windows 18 c are also arranged to be partly overlapped on each side of the small window 18 a .
- the two small windows 18 b are movable so that distance G between the two gloves 16 may be adjusted depending on the body type of the operator. Besides distance G is adjustable based on the body type of the operator, the small window 18 a and small windows 18 b as well as the small windows 18 b and small windows 18 c are partly overlapped. Therefore, changing distance G causes no opening to be formed between the small windows 18 a to 18 c.
- FIGS. 10A and 10B are longitudinal sectional views of a chemical hazard safety cabinet 1 , FIG. 10A showing a state of operation performed with a front opening 6 kept open and FIG. 10B showing a state of operation performed with a glove panel 20 provided in a front opening 6 .
- FIG. 11 is a diagram for describing the characteristic of a blower 5 which controls an inward air flow 7 in the above two states.
- the front opening 6 is formed below a front shutter 4 and the blower 5 sucks air from a workspace 3 to form an inward air flow 7 .
- the glove panel 20 is installed in the front opening 6 , and the front shutter 4 is lowered thereby lowering the positions of the gloves 16 attached to the front shutter 4 .
- the front opening 6 is almost air-tightly closed, so that the outside air sucked in by the blower 5 via the front opening 6 is reduced.
- pressure Pa in the workspace 3 in the state shown in FIG. 10A and pressure Pb in the workspace 3 in the state shown in FIG. 10B become different.
- the blower 5 is assumed to have an ordinary fan characteristic represented, in FIG. 11 , by the outer curve Ho.
- the pressure in the workspace 3 is Pa and the blower load is L 1 .
- the resistance against air sucking increases and the pressure in the workspace 3 rises to Pb thereby increasing the blower load to L 2 .
- Pressures Pa and Pb in the workspace 3 into which air is sucked in are both negative.
- the workspace 3 is separated from the outside space by installing the glove panel 20
- the pressure in the workspace 3 continues lowering.
- the cabinet 1 may be, depending on its construction, vibrated by a forcefully formed inward air flow.
- a differential pressure sensor 23 to detect a negative pressure is provided in a boundary portion of the workspace 3 .
- the differential pressure sensor 23 measures the pressure difference between the pressure in the workspace 3 and the pressure on the secondary side (on the blower 5 side) of a HEPA filter 12 or between the pressure in the workspace 3 and the pressure at outside the cabinet 1 .
- the differential pressure sensor 23 detects that the pressure in the workspace 3 has risen to Pb
- the output of the blower 5 is controlled by controlling the operating frequency of or the voltage applied to an inverter 26 driving the blower 5 so as to operate the blower 5 in accordance with a controlled blower characteristic Hc represented, in FIG.
- the output of the blower 5 may be controlled also by attaching a detector to detect the glove panel 20 to a grooved holding member 22 or by installing a limit switch to detect the position of the front shutter 4 .
- a chemical hazard safety cabinet is provided as a biosafety cabinet which allows operation to be performed, depending on the degree of hazard of contaminants to be handled, either through a front opening or using sealed gloves whose positions are variable. This improves the workability of operation performed using a biosafety cabinet.
Abstract
Description
- The present application claims priority from Japanese application 2010-163031 filed on Jul. 20, 2010, the content of which is hereby incorporated by reference into this application.
- The present invention relates to draft chambers, class II biohazard safety cabinets, and chemical hazard safety cabinets (may hereinafter be referred to collectively as “biosafety cabinets”) and, more particularly, to a biosafety cabinet suitable for use in handling contaminants in a workspace formed therein.
- Draft chambers, cabinets for use in the nanotechnological field, and chemical hazard safety cabinets (may hereinafter be referred to collectively as “biosafety cabinets”) include, in many cases, an internal workspace where operation can be performed. A cabinet having such a workspace includes a front shutter and a front opening formed below the front shutter. An operator can extend his/her arms through the front opening into the cabinet and handle, for example, nanomaterial or chemically contaminated material. To prevent the operator from being contaminated by nanomaterial or chemically contaminated material, a flow of inward air being sucked into the cabinet or an air barrier is formed in the front opening.
- To more strictly prevent contaminants from coming into contact with the operator, material to be handled is placed in a glove box making up an air-tight workspace, then the operator inserts his/her arms in hand-shaped gloves attached to the front of the workspace separating the workspace from the outside space and handles the material via the gloves. In the case of a chemical hazard safety cabinet or glove box, a high efficiency particulate air (HEPA) filter is used to remove contaminants generated in the workspace so as to safely discharge only clean air to outside the cabinet or glove box. An example of such an existing type of biosafety cabinet is disclosed in Japanese Patent Laid-Open No. 2007-163053.
- When an existing type of biosafety cabinet as described above is used, an operator extends his/her arms through glove insertion ports formed in the front of a workspace and handles contaminants placed on a work surface disposed in the workspace. In this type of biosafety cabinet, the positions of the gloves worn by the operator are fixed, so that there are cases in which the location in the workspace where the material to be handled can be placed is restricted or in which the operator's performance is restricted depending on his/her body type. Note that the glove positions are fixed as a result of attaching importance to the air-tightness of the biosafety cabinet. In fact, the biosafety cabinet incorporates strict measures against chemical contamination and biohazards.
- The present invention has been made in view of the above problem, and it is an object of the present invention to improve the workability of operation to be performed, while preventing chemical or biological contamination, using a biosafety cabinet and gloves attached to the cabinet. Another object of the present invention is to improve the workability of operation to be performed, while taking measures against biohazards and chemical hazards, using a biosafety cabinet and gloves attached to the cabinet.
- To solve the above problem, the present invention provides a biosafety cabinet comprising an air exhaust unit for discharging air in a workspace formed in a main body cabinet to outside via a filter, a front shutter vertically movably installed on a front of the workspace, and a front opening formed below the front shutter at a front of the workspace. In the biosafety cabinet, the front shutter is provided with a plurality of small windows which are laterally movable and which are overlapped like layered sliding doors. One of the plurality of small windows is provided, on the workspace side thereof, with a pair of glove ports to which a pair of gloves for use in operation in the workspace can be air-tightly attached.
- The biosafety cabinet according to the present invention may be configured such that only one of the plurality of small windows is attached with a pair of the gloves or such that two of the plurality of small windows are each attached with one of the gloves. Also, in the biosafety cabinet, a holding groove may be provided on each lateral side of the front opening, the holding groove being for removably holding a corresponding lateral end portion of a laterally outermost one of the plurality of small windows on each side. Furthermore, the biosafety cabinet preferably further comprises a differential pressure sensor for detecting a differential pressure between a pressure in the workspace and a pressure outside the biosafety cabinet or between the pressure in the workspace and a pressure at downstream of the filter and a control unit for controlling an output of the exhaust unit according to a differential pressure signal inputted from the differential pressure sensor. Still furthermore, the biosafety cabinet may further comprise a glove panel removably installed in the front opening to be below the front shutter, the glove panel being attached with a glove.
- According to the present invention, a biosafety cabinet has gloves movably attached to a front cover thereof, so that the workability of operation to be performed, while preventing chemical contamination or biological contamination, using the gloves can be improved. Also, the workability of operation to be performed, while taking measures against biohazards or chemical hazards, using the gloves attached to the biosafety cabinet can be improved.
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FIGS. 1A and 1B show a chemical hazard safety cabinet according to an embodiment (a first embodiment) of the present invention,FIG. 1A being a longitudinal sectional view andFIG. 1B being a front view. -
FIGS. 2A and 2B show the cabinet shown inFIGS. 1A and 1B in a state with a front shutter thereof closed,FIG. 2A being a longitudinal sectional view andFIG. 2B being a front view. -
FIGS. 3A and 3B show the cabinet shown inFIGS. 1A and 1B in a state with gloves moved left,FIG. 3A being a longitudinal sectional view andFIG. 3B being a front view. -
FIG. 4 is a front view of the cabinet shown inFIGS. 1A and 1B with the gloves moved right. -
FIGS. 5A to 5D show the front shutter of the cabinet shown inFIGS. 1A and 1B ,FIGS. 5A and 5B being horizontal sectional views andFIGS. 5C and 5D being partial horizontal sectional views. -
FIGS. 6A and 6B show a chemical hazard safety cabinet according to another embodiment (a second embodiment) of the present invention,FIG. 6A being a longitudinal sectional view andFIG. 6B being a front view. -
FIG. 7 is a horizontal sectional view of the front shutter of the cabinet shown inFIGS. 6A and 6B . -
FIGS. 8A and 8B show a chemical hazard safety cabinet according to still another embodiment (a third embodiment) of the present invention,FIG. 8A being a longitudinal sectional view andFIG. 8B being a front view. -
FIG. 9 is a horizontal sectional view of the front shutter of the cabinet shown inFIGS. 8A and 8B . -
FIGS. 10A and 10B show a chemical hazard safety cabinet according to still another embodiment (a fourth embodiment) of the present invention,FIG. 10A being a longitudinal sectional view andFIG. 10B being a front view. -
FIG. 11 is a diagram for describing air flow rate control performed in the cabinet shown inFIGS. 10A and 10B . - With reference to drawings, embodiments, according to the present invention, of chemical hazard safety cabinets which are among biosafety cabinets will be described below. Needless to say, the present invention can also be applied to other types of biosafety cabinets.
- With reference to
FIGS. 1A-1B toFIGS. 5A-5D , a first embodiment of a chemical hazard safety cabinet according to the present invention will be described below.FIGS. 1A and 1B show a chemicalhazard safety cabinet 1,FIG. 1A being a longitudinal sectional view andFIG. 1B being a front view. Thecabinet 1 has afront shutter 4 vertically movably installed on a front of aworkspace 3 formed inside amain body case 1 a. When thefront shutter 4 is lifted, afront opening 6 of theworkspace 3 appears below thefront shutter 4. When thefront shutter 4 is in a lowered position, thefront opening 6 is closed. - A
HEPA filter path 12 a is formed in upper and lower portions, behind theworkspace 3, of the interior of themain body case 1 a. TheHEPA filter path 12 a is used to filter contaminants and dust generated in theworkspace 3 for air purification. In an upper portion of space behind theworkspace 3, aplastic bag 15 for accommodating the contaminatedHEPA filter 12 is held. Aspace 12 b on the downstream side of theHEPA filter 12 is a clean space separated from theworkspace 3 by aHEPA filter cover 13. TheHEPA filter cover 13 is fitted with a packing 14 for enhanced sealing. - A wire mesh is installed in a lower back side of the
workspace 3 to prevent the operator's hands from entering theHEPA filter path 12 a. In the portion corresponding to theworkspace 3 of theHEPA filter path 12 a, aprefilter 11 and theHEPA filter 12 are disposed with the latter being above the former. Ablower 5 is attached upward of theHEPA filter 12. Anexhaust port 8 is formed in the main body case la to be on the outlet side of theblower 5. The bottom of theworkspace 3 is used as awork surface 2. - In the chemical
hazard safety cabinet 1 constructed as described above, air flows as follows. Ambient air is introduced into thecabinet 1 through thefront opening 6 formed below thefront shutter 4 and forms aninward air flow 7. Theinward air flow 7 enters theworkspace 3 and is sucked in to pass theprefilter 11 to havecontaminants 10 contained in the air removed by theHEPA filter 12. The HEPA-filtered air is then sucked in by theblower 5 to be discharged asexhaust air 9 through theexhaust port 9 formed in themain body case 1 a. The operator, not shown, extends his/her arms into theworkspace 3 through thefront opening 6 and handles thecontaminants 10, i.e. samples, in theworkspace 3. Theinward air flow 6 formed at thefront opening 6 prevents thecontaminants 10 generated in or brought into theworkspace 3 from leaking out of thecabinet 1. - The
front shutter 4 hassmall windows 18 a to 18 c formed therein. Thesmall windows 18 a to 18 c are horizontally movable in thefront shutter 4. They are made of a transparent material, for example, glass, so that the interior of theworkspace 3 can be seen from outside thecabinet 1. - When the
blower 5 is operated, theinward air flow 7 to be sucked into thecabinet 1 is formed at thefront opening 6 making the pressure inside theworkspace 3 negative (−). With theinward air flow 7 formed, when the operator extends his/her arms through thefront opening 6 to handle thecontaminants 10 in theworkspace 3, neither thecontaminants 10 are inhaled by the operator nor they leak out of thecabinet 1. - The
contaminants 10 handled in theworkspace 3 are removed by theprefilter 11 and theHEPA filter 12, allowing only clean air to be discharged from theexhaust port 8. This causes thecontaminants 10 to be accumulated at theHEPA filter 12. Eventually, theHEPA filter 12 is clogged and becomes unable to satisfactorily pass air. When this occurs, it is necessary to replace theHEPA filter 12. - To remove the
HEPA filter 12, remove theHEPA filter cover 13 provided on theworkspace 3 side of theplastic bag 15 that is disposed on the front side of theHEPA filter 12, then take out theHEPA filter 12 holding it via theplastic bag 15 while covering theHEPA filter 12 with theplastic bag 15. - In this way, the operator can take out the
HEPA filter 12 enclosed in theplastic bag 15 without touching thecontaminants 10 collected by theHEPA filter 12. This procedure is used in cases where there is no means of effectively neutralizing thecontaminants 10 collected by theHEPA filter 12. How to install anew HEPA filter 12 after removing theold HEPA filter 12 will be omitted in this specification. -
FIGS. 2A and 2B show the chemicalhazard safety cabinet 1 shown inFIGS. 1A and 1B in a state with thefront shutter 4 closed,FIG. 2A being a longitudinal sectional view andFIG. 2B being a front view. When, as shown inFIGS. 1A and 1B , thefront opening 6 is open, the operator can extend his/her arms into theworkspace 3 through thefront opening 6 and handle thecontaminants 10 with theinward air flow 7 preventing thecontaminants 10 from leaking out. In cases where, in handling thecontaminants 10, the air barrier effect of theinward air flow 7 only is not regarded satisfactory as means of separating theworkspace 3 from outside thecabinet 1, thefront shutter 4 is closed as shown inFIGS. 2A and 2B . - The small
transparent windows 18 a to 18 c provided in thefront shutter 4 are horizontally movable in thefront shutter 4. Thesmall window 18 a includesglove ports 17 to whichgloves 16 are air-tightly attached, so that the operator can handle thecontaminants 10 in theworkspace 3 via thegloves 16. In this state, theinward air flow 7 sucked in by theblower 5 enters theworkspace 3 through the clearance between thefront shutter 4 and themain case 1 a making the pressure inside theworkspace 3 negative. - In the above-described way, with the
front opening 6 closed between the operator and theworkspace 3, the possibility of thecontaminants 10 leaking out toward the operator is extremely reduced. Moreover, thecontaminants 10 are handled via thegloves 16, so that the operator does not come in direct contact with thecontaminants 10. - With reference to
FIGS. 3A and 3B ,FIG. 4 , andFIGS. 5A to 5D , the horizontal movement of thesmall windows 18 a to 18 c will be described below.FIGS. 3A and 3B show thecabinet 1 in a state in which thefront shutter 4 is closed and thesmall window 18 a including theglove ports 17 has been moved to the left to allow thesmall windows - 4 shows the
cabinet 4 in a state in which thesmall window 18 a including theglove ports 17 has been moved to the right to allow thesmall windows FIGS. 3A and 3B ,FIG. 3A is a longitudinal sectional view andFIG. 3B is a front view. - When the cabinet is in the state shown in
FIGS. 2A and 2B , thegloves 16 are positioned in a lateral center portion of thefront shutter 4, so that there can be cases where the operator cannot reach a side of theworkspace 3. To allow the operator to reach either side of theworkspace 3, the horizontally movable, transparentsmall window 18 a provided in thefront shutter 4 is moved to the right or to the left as shown inFIG. 3B or as shown inFIG. 4 . -
FIGS. 5A to 5D are sectional views taken along line A-A inFIG. 2B , showing how thesmall windows 18 a to 18 c are moved and positioned. InFIG. 5A , thesmall window 18 a is shown in a lateral center position. InFIG. 5B , thesmall window 18 a is shown moved to the right side.FIG. 5C is a detailed view of portion C ofFIG. 5B .FIG. 5D is a detailed view of portion D ofFIG. 5B . - The transparent
small window 18 a has twocircular glove ports 17 air-tightly attached thereto. Theglove ports 17 can each be attached with an air-tight glove 16. Thesmall window 18 a is made of a transparent plate, for example, a glass plate and is fitted with rectangular small-window frames 19 being described later. - The
small windows 18 b are disposed, each being like one of layered sliding doors made of glass, on both sides of thesmall window 18 a. Thesmall windows 18 c are disposed, also each being like one of layered sliding doors made of glass, on the lateral outer sides of thesmall windows 18 b. - On the right side of the
small window 18 a moved to the right side as shown inFIG. 5B , thesmall window 18 a and the rightsmall window 18 b, and the rightsmall window 18 c are overlapped in the front-to-rear direction. On the left side of thesmall window 18 a moved to the right side as shown inFIG. 5B , the leftsmall window 18 b is also moved rightward, but the leftsmall window 18 c, the leftsmall window 18 b, and thesmall window 18 a remain connected by small-window frames 19, being described in the following, fitted to their lateral end portions. - The
small windows 18 a to 18 c are, as described above, plate members, and the left and right sides of each of thesmall windows 18 a to 18 c are each fitted with a rectangular small-window frame 19. The small-window frames 19 fitted to thesmall windows 18 b positioned between thesmall window 18 a and thesmall windows 18 c partly differ in shape from the small-window frames 19 fitted to thesmall windows window frames 19 fitted to each of thesmall windows 18 b, the outer small-window frame 19 has twoprojections 19 a each having a rectangular cross-section. Of the twoprojections 19 a, one is formed in a lateral inner end portion (lateral end portion closer to the lateral center of the front shutter 4) on the front side of the outer small-window frame 19 and the other is formed in a lateral outer end portion (lateral end portion farther from the lateral center of the front shutter 4) on the back side of the outer small-window frame 19. The inner small-window frame 19, on the other hand, has only oneprojection 19 a formed in a lateral inner end portion on the front side thereof. - In the above configuration, when the
small window 18 a is moved rightward, on the left side of thesmall window 18 a, after only thesmall window 18 a is initially moved, the left small-window frame 19 fitted to thesmall window 18 a comes into sliding contact with the right small-window frame 19 fitted to the leftsmall window 18 b to eventually hit thefront projection 19 a of the right small-window frame 19. This causes the leftsmall window 18 b to be pulled rightward by thesmall window 18 a (seeFIG. 5C ). Thus, moving thesmall window 18 a rightward causes, on the left side of thesmall window 18 a, no opening to be formed between thesmall windows 18 a to 18 c. - On the right side of the
small window 18 a, as thesmall window 18 a is moved rightward, the right small-window frame 19 fitted thereto comes to hit thefront projection 19 a of the right small-window frame 19 fitted to the rightsmall window 18 b to cause the rightsmall window 18 b to also move rightward. When thesmall window 18 a eventually reaches its rightmost position, thesmall windows 18 a to 18 c are overlapped in the front-rear direction as shown inFIG. 5D . - Since the
small windows 18 a to 18 c are bilaterally symmetrical, moving thesmall window 18 a leftward causes, on the right side of thesmall window 18 a, no opening to be formed between thesmall windows 18 a to 18 c, either. According to the present embodiment, thegloves 16 can be easily moved horizontally, whether to left or right. This increases the degree of freedom of operation to be performed using thegloves 16. - With reference to
FIGS. 6A , 6B, and 7, a second embodiment of a chemical hazard safety cabinet according to the present invention will be described below.FIGS. 6A and 6B show a chemicalhazard safety cabinet 1,FIG. 6A being a longitudinal sectional view andFIG. 6B being a front view.FIG. 7 is a sectional view, taken along line E-E inFIG. 6B , of afront shutter 4 included in thecabinet 1 shown inFIGS. 6A and 6B . The second embodiment differs from the first embodiment in that afront opening 6 is provided with aglove panel 20. Excepting this difference, the configuration of the second embodiment is the same as that of the first embodiment. - Referring to
FIGS. 6A and 6B , a grooved holdingmember 22 is provided on each side of thefront opening 6. Theglove panel 20 is held, at both sides thereof, by the grooved holdingmembers 22. Thegrooved holding members 22 are positioned inwardly of thefront shutter 4, i.e. to be more inside aworkspace 3 than thefront shutter 4. Theglove panel 20 is installed in position by being inserted, from above, into the grooves of the grooved holdingmembers 22. - As shown in
FIG. 7 , theglove panel 20 is installed on theworkspace 3 side of thefront shutter 4. Thus, with theglove panel 20 installed to be more inside than being directly below thefront shutter 4, thefront shutter 4 can be lifted and lowered in a range where thegloves 16 attached to thefront shutter 4 are not hit. - The above configuration will be effective, for example, in cases where, with the
front shutter 4 completely lowered, theglove ports 17 of thefront shutter 4 are positioned too low to allow the operator to conveniently use thegloves 16 attached to theglove ports 17. Even in cases where: the vertical positions of thegloves 16 attached to thefront shutter 4 are appropriately adjusted; thefront opening 6 is formed below thefront shutter 4; and thegloves 16 are used by the operator in handling thecontaminants 10; the air barrier effect of aninward air flow 7 alone might be inadequate to prevent thecontaminants 10 from leaking out. In such cases, too, the above configuration can be effective. - When the
front opening 6 is provided with theglove panel 20, thecabinet 1 hasgloves 16 in two levels, i.e. theupper gloves 16 attached to thefront shutter 4 and thelower gloves 16 attached to theglove panel 20, any combination of which can be selected by the operator depending on the type of operation to be performed or his/her body type. Also, with theplural gloves 16 provided, plural operators can simultaneously participate in operation to be performed in theworkspace 3. - In cases where, without the
glove panel 20 installed, theinward air flow 7 is used as an air barrier to separate theworkspace 3 and the outside space, theinward air flow 7 is blocked when plural operators stand in front of thefront opening 6. As a result, the air barrier effect of theinward air flow 7 is lost possibly allowing thecontaminants 10 to leak out from theworkspace 3. According to the present embodiment, theglove panel 20 is installed to separate theworkspace 3 from the outside space, so that thecontaminants 10 in theworkspace 3 are prevented from leaking out even when plural operators stand in front of thecabinet 1. Even though, in the present embodiment, theglove panel 20 is provided on theworkspace 3 side of thefront shutter 4, the same effect can be obtained also by providing theglove panel 20 in front of thefront shutter 4. - With reference to
FIGS. 8A , 8B, and 9, a third embodiment of a chemical hazard safety cabinet according to the present invention will be described below.FIGS. 8A and 8B show a chemicalhazard safety cabinet 1,FIG. 8A being a longitudinal sectional view andFIG. 8B being a front view.FIG. 9 is a sectional view, taken along line F-F inFIG. 8B , of afront shutter 4 included in thecabinet 1 shown inFIGS. 8A and 8B . - The third embodiment differs from the first embodiment in that
glove ports 17 are provided not in a centralsmall window 18 a but in left and rightsmall windows 18 b. No glove port is provided in thesmall window 18 a. The centralsmall window 18 a is positioned between the left and rightsmall windows 18 b. Distance G between the twogloves 16 can be changed. - The
small window 18 a and thesmall windows 18 b are arranged to be partly overlapped. Thesmall windows 18 b and thesmall windows 18 c are also arranged to be partly overlapped on each side of thesmall window 18 a. The twosmall windows 18 b are movable so that distance G between the twogloves 16 may be adjusted depending on the body type of the operator. Besides distance G is adjustable based on the body type of the operator, thesmall window 18 a andsmall windows 18 b as well as thesmall windows 18 b andsmall windows 18 c are partly overlapped. Therefore, changing distance G causes no opening to be formed between thesmall windows 18 a to 18 c. - With reference to
FIGS. 10A , 10B, and 11, a fourth embodiment of a chemical hazard safety cabinet according to the present invention will be described below.FIGS. 10A and 10B are longitudinal sectional views of a chemicalhazard safety cabinet 1,FIG. 10A showing a state of operation performed with afront opening 6 kept open andFIG. 10B showing a state of operation performed with aglove panel 20 provided in afront opening 6.FIG. 11 is a diagram for describing the characteristic of ablower 5 which controls aninward air flow 7 in the above two states. - Referring to
FIG. 10A , thefront opening 6 is formed below afront shutter 4 and theblower 5 sucks air from aworkspace 3 to form aninward air flow 7. Referring toFIG. 10B , theglove panel 20 is installed in thefront opening 6, and thefront shutter 4 is lowered thereby lowering the positions of thegloves 16 attached to thefront shutter 4. In this state, thefront opening 6 is almost air-tightly closed, so that the outside air sucked in by theblower 5 via thefront opening 6 is reduced. As a result, pressure Pa in theworkspace 3 in the state shown inFIG. 10A and pressure Pb in theworkspace 3 in the state shown inFIG. 10B become different. - In the present embodiment, the
blower 5 is assumed to have an ordinary fan characteristic represented, inFIG. 11 , by the outer curve Ho. In the state shown inFIG. 10A in which thefront opening 6 is provided, the pressure in theworkspace 3 is Pa and the blower load is L1. In the state shown inFIG. 10B in which theglove panel 20 is installed, the resistance against air sucking increases and the pressure in theworkspace 3 rises to Pb thereby increasing the blower load to L2. Pressures Pa and Pb in theworkspace 3 into which air is sucked in are both negative. When, as shown inFIG. 10B , theworkspace 3 is separated from the outside space by installing theglove panel 20, the pressure in theworkspace 3 continues lowering. When, in such a state, theblower 5 continues sucking air from theworkspace 3 separated from the outside space, thecabinet 1 may be, depending on its construction, vibrated by a forcefully formed inward air flow. - In the present embodiment, to address the above problem, a
differential pressure sensor 23 to detect a negative pressure is provided in a boundary portion of theworkspace 3. Thedifferential pressure sensor 23 measures the pressure difference between the pressure in theworkspace 3 and the pressure on the secondary side (on theblower 5 side) of aHEPA filter 12 or between the pressure in theworkspace 3 and the pressure at outside thecabinet 1. When, for example, as a result of installing theglove panel 20, thedifferential pressure sensor 23 detects that the pressure in theworkspace 3 has risen to Pb, the output of theblower 5 is controlled by controlling the operating frequency of or the voltage applied to aninverter 26 driving theblower 5 so as to operate theblower 5 in accordance with a controlled blower characteristic Hc represented, inFIG. 11 , by the inner solid-line curve. As a result, the pressure in theworkspace 3 lowers to Pb″ between pressures Pa and Pb. This prevents theblower 5 from excessively sucking air and contributes toward energy saving. By monitoring the differential pressure between the inside of theworkspace 3 and the secondary side of theHEPA filter 12, the life (clogging) of theHEPA filter 12 can also be monitored. - Even though, in the present embodiment, the
differential pressure sensor 23 is used, the output of theblower 5 may be controlled also by attaching a detector to detect theglove panel 20 to a grooved holdingmember 22 or by installing a limit switch to detect the position of thefront shutter 4. - According to the above embodiments of the present invention, a chemical hazard safety cabinet is provided as a biosafety cabinet which allows operation to be performed, depending on the degree of hazard of contaminants to be handled, either through a front opening or using sealed gloves whose positions are variable. This improves the workability of operation performed using a biosafety cabinet.
Claims (15)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2010163031A JP5416666B2 (en) | 2010-07-20 | 2010-07-20 | Safety cabinet |
JP2010-163031 | 2010-07-20 |
Publications (2)
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US20120019110A1 true US20120019110A1 (en) | 2012-01-26 |
US9144910B2 US9144910B2 (en) | 2015-09-29 |
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Application Number | Title | Priority Date | Filing Date |
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US13/186,807 Active 2033-11-18 US9144910B2 (en) | 2010-07-20 | 2011-07-20 | Biosafety cabinetry |
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US (1) | US9144910B2 (en) |
JP (1) | JP5416666B2 (en) |
SG (1) | SG177861A1 (en) |
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CN104097216A (en) * | 2014-07-30 | 2014-10-15 | 万英南 | Glove box system for removing hydrogen fluoride |
CN104770990A (en) * | 2015-02-28 | 2015-07-15 | 马晓琳 | Chemical agent storage cabinet |
CN105457964A (en) * | 2016-01-28 | 2016-04-06 | 王斌 | Ventilation hood with safe movable protection window |
US20160100896A1 (en) * | 2014-10-09 | 2016-04-14 | Hansen Medical, Inc. | Systems and methods for aligning an elongate member with an access site |
JP2016083591A (en) * | 2014-10-23 | 2016-05-19 | ヤマト科学株式会社 | Arm insertion opening type hood |
US20180194257A1 (en) * | 2015-04-23 | 2018-07-12 | Eismann Innvations Gmbh | Vehicle having a device for processing food |
US20180250835A1 (en) * | 2017-03-01 | 2018-09-06 | Cl Schutzrechtsverwaltungs Gmbh | Handling device for an apparatus for the additive manufacture of three-dimensional objects |
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US20190381433A1 (en) * | 2016-11-28 | 2019-12-19 | Iyam Lynch | Device that selectively delivers molecular active components and reduces airborne contaminants |
CN112373955A (en) * | 2020-11-10 | 2021-02-19 | 苏州贝康智能制造有限公司 | Heat preservation cabin convenient to manual intervention and heat preservation cabin system |
CN114206498A (en) * | 2019-07-30 | 2022-03-18 | 斯康股份公司 | Glove arrangement for protected access to a container |
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JP6088155B2 (en) * | 2012-04-27 | 2017-03-01 | ヤマト科学株式会社 | Hand arm insertion opening movable hood |
JP5968694B2 (en) * | 2012-06-26 | 2016-08-10 | 澁谷工業株式会社 | Isolation work device and work method of isolation work device |
JP5724000B1 (en) * | 2014-01-30 | 2015-05-27 | 株式会社日本医化器械製作所 | Globe panel |
KR102151700B1 (en) * | 2020-04-03 | 2020-09-04 | 김상일 | Medical treatment booth |
KR102222135B1 (en) * | 2020-04-14 | 2021-03-02 | 오윤경 | Foldable shielding and disinfection booth |
JP7341968B2 (en) * | 2020-09-28 | 2023-09-11 | 株式会社日立産機システム | safety cabinet |
JP7445091B1 (en) | 2022-07-26 | 2024-03-06 | 株式会社日立産機システム | safety work equipment |
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CN104097216A (en) * | 2014-07-30 | 2014-10-15 | 万英南 | Glove box system for removing hydrogen fluoride |
US20160100896A1 (en) * | 2014-10-09 | 2016-04-14 | Hansen Medical, Inc. | Systems and methods for aligning an elongate member with an access site |
JP2016083591A (en) * | 2014-10-23 | 2016-05-19 | ヤマト科学株式会社 | Arm insertion opening type hood |
CN104770990A (en) * | 2015-02-28 | 2015-07-15 | 马晓琳 | Chemical agent storage cabinet |
US10350588B2 (en) | 2015-03-10 | 2019-07-16 | Hitachi Industrial Equipment Systems Co., Ltd. | Clean air apparatus |
US20180194257A1 (en) * | 2015-04-23 | 2018-07-12 | Eismann Innvations Gmbh | Vehicle having a device for processing food |
US10604055B2 (en) * | 2015-04-23 | 2020-03-31 | Zume Pizza, Inc. | Vehicle having a device for processing food |
CN105457964A (en) * | 2016-01-28 | 2016-04-06 | 王斌 | Ventilation hood with safe movable protection window |
US20190381433A1 (en) * | 2016-11-28 | 2019-12-19 | Iyam Lynch | Device that selectively delivers molecular active components and reduces airborne contaminants |
US11666842B2 (en) * | 2016-11-28 | 2023-06-06 | Iyam Lynch | Device that selectively delivers molecular active components and reduces airborne contaminants |
US20180250835A1 (en) * | 2017-03-01 | 2018-09-06 | Cl Schutzrechtsverwaltungs Gmbh | Handling device for an apparatus for the additive manufacture of three-dimensional objects |
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CN109909252A (en) * | 2019-03-27 | 2019-06-21 | 三明学院 | A kind of laboratory fume hood |
CN114206498A (en) * | 2019-07-30 | 2022-03-18 | 斯康股份公司 | Glove arrangement for protected access to a container |
CN112373955A (en) * | 2020-11-10 | 2021-02-19 | 苏州贝康智能制造有限公司 | Heat preservation cabin convenient to manual intervention and heat preservation cabin system |
Also Published As
Publication number | Publication date |
---|---|
JP2012024657A (en) | 2012-02-09 |
JP5416666B2 (en) | 2014-02-12 |
US9144910B2 (en) | 2015-09-29 |
SG177861A1 (en) | 2012-02-28 |
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