US20130073034A1 - Leaflet Reinforcement For Regurgitant Valves - Google Patents
Leaflet Reinforcement For Regurgitant Valves Download PDFInfo
- Publication number
- US20130073034A1 US20130073034A1 US13/673,886 US201213673886A US2013073034A1 US 20130073034 A1 US20130073034 A1 US 20130073034A1 US 201213673886 A US201213673886 A US 201213673886A US 2013073034 A1 US2013073034 A1 US 2013073034A1
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- US
- United States
- Prior art keywords
- support
- downstream
- leaflet
- valve leaflet
- upstream
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2463—Implants forming part of the valve leaflets
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
A support, and a method for attaching said support, for providing additional strength to existing regurgitant or prolapsed valve leaflets. The support restores an otherwise non-functioning, or poorly functioning, native valve to a functioning condition, obviating the need for a complete valve removal or replacement. The support may also be applied to a functioning valve leaflet as a prophylactic measure against future failure. The delivery method includes a delivery mechanism for attaching the support to the native valve leaflet.
Description
- This application is a divisional of U.S. patent application Ser. No. 10/613,121 filed Jul. 3, 2003 entitled Leaflet Reinforcement For Regurgitant Valves, which claims the benefit of U.S. Provisional Application No. 60/393,794, filed Jul. 3, 2002, the contents of both of which are hereby incorporated by reference in their entireties.
- Blood vessel valves include flexible tissue leaflets that passively alternate between open and closed positions as the forces of a blood stream act upon them. As blood flows in a first direction, the leaflets are urged apart from each other, and allow the blood to pass. Between pulses, as the blood attempts to flow in a reverse direction, the blood acts upon upstream surfaces of the individual leaflets, causing the leaflets to move inwardly. As the leaflets move inwardly, the edges of the individual leaflets (two, in the case of bicuspid valves, and three in the case of tricuspid valves) abut against each other, effectively blocking the blood flow in the reverse direction.
- If the individual leaflets suffer degradation in structural integrity, such as degeneration, a prolapse condition may result.
FIGS. 1 through 3 demonstrate the mechanics of a regurgitant valve with leaflet prolapse.FIGS. 1 a and 1 b show ahealthy tricuspid valve 1 in the open position. The direction of blood flow is indicated byarrow 2. Thevalve 1 includes threeleaflets 3 growing into the lumen of ablood vessel 4. It can be seen that when the blood is flowing in the direction shown byarrow 2 ofFIG. 1 a, theflexible valve leaflets 3 naturally fold themselves against the interior walls of theblood vessel 4, thereby minimizing their impact on blood flow in that direction. - As depicted in
FIG. 2 a, when blood attempts to flow in the reverse direction, between cardiac pulses, thesevalve leaflets 3 move inward, toward each other. As best shown inFIG. 2 b, when theleaflets 3 abut, they form aseal 5, effectively preventing fluid flow in the direction ofarrows 2 fromFIG. 2 a. Theseal 5 can only be formed if all threevalve leaflets 3 are structurally sound. - When a valve, such as
valve 1 ofFIG. 3 , has a prolapsedleaflet 3 a, theseal 5 cannot be effectively formed.Leaflet 3 a lacks the structural integrity of thehealthy leaflets 3. When the flow is reversed, as indicated byarrow 2, thehealthy leaflets 3 balloon inwardly. However, the prolapsedleaflet 3 a falls away from theseal 5, leaving asignificant gap 6 in theseal 5. Blood passes through thegap 6, resulting in a loss of systolic pressure, as well as a reduction in the pumping efficacy of the heart. - Current methods of repairing prolapsed valves involve replacing the valve entirely with a prosthetic valve. The structurally sound leaflets are not preserved. It would be advantageous to provide a method of repairing a prolapsed valve, leaving as much of the native valve as possible intact, thereby minimizing the risk of rejection, and preserving the healthy leaflets. Percutaneous treatment would obviate the risks associated with open heart surgery.
- In one aspect of the present invention, there is a method for repairing a prolapsed valve that involves reinforcing the prolapsed leaflet or leaflets to reestablish the structural integrity thereof. The method involves attaching a support to one or both sides of the valve. The support is constructed and arranged to allow the leaflet to open when blood is flowing through the valve in the natural direction. When the flow is reversed during a diastole, the support resists, preventing the leaflet from prolapsing.
- In another aspect of the present invention, a support is provided that is attachable to the downstream side of a prolapsed valve leaflet. The support includes an attachment mechanism, preferably barbs, staples, or similar suitable tissue-grabbing means. The support may be bifurcated with one or more hinge, allowing one side of the support to pivot relative to the second side. The hinge is constructed and arranged with a stop, so that the hinge prevents pivoting past a sealing point. Preferably, the hinge is constructed to avoid pinching the leaflet tissue with the stop is reached.
- Another aspect of the present invention provides a support that is attachable to the upstream side of a prolapsed valve leaflet. The construction of the upstream support is very similar to that of the downstream support. The upstream support also includes an attachment mechanism, preferably barbs, staples, or similar suitable tissue-grabbing means. Again, the support may be bifurcated with one or more hinge, allowing one side of the support to pivot relative to the other side. The hinge is also constructed and arranged with a stop, so that the hinge prevents pivoting past a sealing point. Placing the support on the upstream side of the valve may be advantageous because the stress encountered during diastole, when the support is preventing the leaflet from prolapsing due to the pressure of the blood, acts in conjunction with the attachment mechanism, rather than against it. Thus, the support is less likely to become separated from the leaflet.
- Yet another aspect of the present invention provides a support that includes both upstream and downstream members. These members are similar in construction to the upstream and downstream members. However, the attachment mechanism used in this aspect takes advantage of the additional structure provided by the opposing support. The opposing supports lock together, through the prolapsed leaflet, sandwiching the leaflet therebetween. Preferably, one member includes male connectors, while the other member includes corresponding female connectors. Alternatively, each side includes one or more male and one or more female connectors, and the other member includes corresponding mating connectors. Whereas the downstream member may provide a single hinge, the upstream member may provide a double or triple hinge, constructed and arranged to allow the upstream member to move with the downstream member, without changing the relative position between the two members. Providing such an arrangement avoids the occurrence of locked hinges and/or tearing the leaflet tissue between the two members. Alternatively, one or both supports may be hingeless.
- Still another aspect of the present invention provides a support with a more complex, multi-member structure, flexible in one direction but rigid in another direction. This structure obviates the necessity of hinges. The support members form a frame with either an open or covered interior.
- A further aspect of the present invention includes a woven, pressed, laminar or similar substrate-like hingeless support. This support operates on the principle that strength is achieved in an otherwise flimsy substrate when the substrate is curved. This principle is easily demonstrated by holding a piece of paper while imparting a curve onto the paper with one's fingers. The paper can be made to easily support itself or even to hold other objects on the concave side, without supporting opposite sides of the paper. However, placing pressure on the convex side of the curved paper causes the paper to quickly bend. Steel tape measures operate on this principle. The tape measures are curved and can be bent easily in one direction but are relatively rigid in the opposite direction.
- Yet another aspect of the present invention includes a method of attaching a support to a prolapsed valve leaflet. The method involves passing a wire from the aorta through the prolapsed valve. A catheter is then guided over the wire that contains the support mechanism. Preferably, the support mechanism includes a biasing means that allows the support to be pre-loaded in the catheter such that, when released from the catheter sheath, the support mechanism attaches itself to the prolapsed valve leaflet. Alternatively, a positioning means is provided so the support members do not require pre-loading in the catheter unit. The positioning means would allow manual manipulation of the support members during placement. The support is preferably removably attached to the leaflet, thereby allowing removal and reattachment if necessary.
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FIG. 1 a is a sectional view of a healthy native tricuspid valve in an open position; -
FIG. 1 b is a sectional view of the valve ofFIG. 1 a taken alonglines 1 b-1 b; -
FIG. 2 a is a sectional view of a healthy tricuspid valve in a closed position; -
FIG. 2 b is a sectional view of the valve ofFIG. 2 a taken alonglines 2 b-2 b; -
FIG. 3 a is a sectional view of a native prolapsed valve; -
FIG. 3 b is a sectional view of the valve ofFIG. 3 a taken alonglines 3 b-3 b; -
FIG. 4 is a perspective view of an unhinged downstream embodiment of the present invention; -
FIG. 5 is a perspective view of a hinged downstream embodiment of the present invention; -
FIG. 6 is an end view of the embodiment ofFIG. 5 attached to a valve leaflet; -
FIG. 7 is a perspective view of a downstream hinge of the present invention; -
FIG. 8 is a perspective view of an unhinged upstream embodiment of the present invention; -
FIG. 9 is a perspective view of a hinged upstream embodiment of the present invention; -
FIG. 10 is a side elevation of a hinged embodiment of the present invention having members on both the upstream and downstream sides of a prolapsed leaflet; -
FIG. 11 is a perspective view of a substrate embodiment of the present invention in a closed position; -
FIG. 12 is a perspective view of a substrate embodiment of the present invention in an open position; -
FIG. 13 is a perspective view of a multi-member structure embodiment of the present invention; -
FIGS. 14 a-d are a series of drawings depicting a preferred method of attaching a support to a prolapsed leaflet; -
FIG. 15 is an elevation of a preferred delivery device of the present invention; and, -
FIG. 16 is a perspective view of a preferred delivery device of the present invention. - Referring now to the Figures, and first to
FIG. 4 , there is shown unhinged embodiment of asupport 10 of the present invention.Support 10 includes asupport member 12, which is curved to approximately match the curve of a healthy valve leaflet in a closed position. The curve defines aconvex side 14 and aconcave side 16 of thesupport member 12. A plurality ofbarbs 18 extend from thesupport member 12, and are constructed and arranged to penetrate and catch the tissue of a prolapsed leaflet, securing thesupport member 12 thereto. That thebarbs 18 extend from the convex side indicates that thesupport 10 ofFIG. 4 is constructed and arranged for attachment to the downstream side of a prolapsed leaflet. - The
support 10 is a biocompatible material. Acceptable biocompatible metals that could be used to construct thesupport 10 include, but are not limited to, Nitonol, stainless steel, titanium, and other appropriate metals. Acceptable non-metal biocompatible materials include, but are not limited to, PTFE, pyrolytic carbon, or any appropriate polymer. -
FIG. 5 shows a hinged embodiment of asupport 10. Thesupport 10 is bifurcated into afirst part 20 and asecond part 22. Thefirst part 20 and thesecond part 22 are connected with ahinge 24, which allows thesecond part 22 to rotate relative to thefirst part 20. Rather than thebarbs 18 shown inFIG. 4 , thesupport 10 ofFIG. 5 uses a plurality ofstaples 26 as an attachment mechanism.FIG. 6 shows thestaples 26 attaching thesupport 10 to avalve leaflet 3. Thestaples 26 are shown with a hingedembodiment 10 but there is no association between thestaples 26 and thehinge 24. Thebarbs 18 ofFIG. 4 could be used with a hinged embodiment ofsupport 10, and vice versa. - The
hinge 24 is preferably designed to prevent pinching thevalve leaflet 3 during operation.FIG. 7 provides a detailed view of thehinge 24. It can be seen that thehinge 24 includes afirst part component 28, integral with thefirst part 20 and asecond part component 30 integral with thesecond part 22. Thecomponents stop 32 on a side opposite of thevalve leaflet 3. -
FIG. 8 shows asupport 10 constructed and arranged for attachment to an upstream side of a valve leaflet. Again, thesupport member 12 has aconvex side 14 and aconcave side 16. However, the attachment mechanism, shown asbarbs 18, protrudes from theconcave side 16, placing thesupport member 12 on the upstream, convex side of the leaflet. -
FIG. 9 shows a hingedsupport 10 constructed and arranged for attachment to an upstream side of a valve leaflet. Again, the attachment mechanism, a plurality ofbarbs 18, protrudes from theconcave side 16. Thehinge 24 of the upstream, hinged embodiment includes a stop on the upstream side, so as to prevent pinching the leaflet tissue. -
FIG. 10 shows asupport 10 that provides additional support and is less reliant on the structural integrity of the leaflet tissue for attachment purposes than the aforementioned embodiments. Thesupport 10 includes anupstream member 32 and adownstream member 34. Theupstream member 32 is attached to thedownstream member 34 through thevalve leaflet 3 with anattachment mechanism 36. Theattachment mechanism 36 shown includes a plurality ofmale posts 38 that extend through and engagecorresponding apertures 40 through thedownstream member 34. A variety of alternatives may be effectively used asattachment mechanism 36. For example, the male posts could extend from thedownstream member 34 into theupstream member 32. Eachsupport supports leaflet tissue 3. - The
support 10 ofFIG. 10 also includes a hinge assembly 42, however an unhinged two-sided support is also considered within the scope of the present invention. The hinge assembly 42 includes asingle hinge 24 on thedownstream member 34, which may be similar to the hinge shown inFIG. 7 . Theupstream member 32 includes two, or preferably three hinges 44 interconnected with connectingmembers 46. The connectingmembers 46 add length to the hinge assembly 42 such that, when thesupport 10 bends to an open position, the upstream anddownstream members -
FIG. 11 shows an alternative design for asupport 10 that incorporates asubstrate 48. Thesubstrate 48 is preferably a flexible, biocompatible fabric that is at least somewhat resistant to stretching and compressing. The substrate is curved around alongitudinal axis 50 to form aconcave side 52 and aconvex side 54. The curve is imparted to thesubstrate 48 using a heat, mechanical, or chemical forming process. Alternatively, or additionally, acurved brace 56 is included at one end of thesupport 10 that is to be placed near the base of the valve leaflet, proximal the arterial wall. - Imparting a curve around the
longitudinal axis 50 provides a directional strength to thesupport 10 that lends itself to the application of supporting a prolapsed valve leaflet. As seen inFIG. 12 , when blood flows in a systolic direction, the blood pushes on theconvex side 54 of thesupport 10 and causes the support to buckle, allowing the blood to pass through the valve. The curve does not add significant strength to thesupport 10 in this direction. However, when the pressure reverses, such as during diastole, thesupport 10 snaps back into the closed position shown inFIG. 11 . - Pressure against the
concave side 52 is met with the resistance imparted to thesupport 10 by the curve, preventing thesupport 10 from buckling toward theconvex side 54. - The
support 10 ofFIGS. 11 and 12 is versatile enough to be placed on either or both sides of a prolapsed valve. Attachment mechanisms such as staples, permanent sutures, adhesives, magnets, or the like could be used to secure thesupport 10 to the valve leaflet. -
FIG. 13 shows another embodiment of asupport 10 attached to a prolapsedvalve leaflet 3. Thesupport 10 includes anetwork 58 ofinterconnected structures 60. Thestructures 60 are constructed and arranged to allow thesupport 10 to bend in a downstream direction to an open position, yet provides resistance to bending in an upstream direction during a diastole. Thesupport 10 may include a covering over thenetwork 58 or thenetwork 58 may remain open. - A method of securing a
support 10 to a prolapsedvalve leaflet 3 is illustrated inFIGS. 14 a-d. Aguide wire 62 is threaded through ablood vessel 4 to the site where thesupport 10 is to be installed. Acatheter sheath 64, containing thesupport 10, is then fed along theguide wire 62 until thevalve 1 is reached and thesupport 10 is adjacent thetarget leaflet 3. Thesheath 64 is then carefully retracted until thesupport 10 is exposed and free to rotate. - The
support 10 is attached at one end to adelivery mechanism 66, best shown inFIGS. 15 and 16 . Thedelivery mechanism 66 is used to rotate thesupport 10 into place after thesheath 64 is removed. Rotation is achieved by manually pulling on activation strings 68. When thestrings 68 are pulled, thedelivery arms 70 rotate aroundaxles 72 in the directions shown by arrows 74 (FIG. 14 d). Thesupport 10, being temporarily attached to thedelivery arms 70, rotate therewith. It may be necessary to hold acarrier 76, on which thearms 70 are pivotally mounted, when pulling thestrings 68, in order to maintain the position of thedelivery mechanism 66. Once in place, the attachment mechanism of the support penetrates the leaflet, or otherwise fixes thesupport 10 to the leaflet, and allows thedelivery arms 70 to be dislodged from thesupport 10. Thedelivery mechanism 66 andguide wire 62 are then retracted into thesheath 64 and thesheath 64 is removed from the patient. - The
delivery mechanism 66 is shown inFIG. 15 as delivering asupport 10 that includes both anupstream member 32 and adownstream member 34. However, thesame delivery mechanism 66, having twodelivery arms 70, could also be used to deliver supports having only one support member, either upstream or downstream. Theunused arm 70 provides a surface against which the other arm acts to secure the support to the leaflet. The unused arm also provides a surface against which staples, if used as an attachment mechanism, can be folded into an attached arrangement. - The foregoing description addresses embodiments encompassing the principles of the present invention. The embodiments may be changed, modified and/or implemented using various types of arrangements. Those skilled in the art will readily recognize various modifications and changes that may be made to the invention without strictly following the exemplary embodiments and applications illustrated and described herein, and without departing from the scope of the invention, which is set forth in the following claims.
Claims (21)
1. A device useable to attach a support to a valve leaflet comprising:
a sheath;
a delivery mechanism slideably disposed within the sheath, said delivery mechanism constructed and arranged to carry at least one support, whereby when said sheath is retracted to expose said delivery mechanism, said delivery mechanism is moveable such that the support is pressed against the valve leaflet.
2. The device of claim 1 wherein said delivery mechanism comprises at least one delivery arm pivotally attached to a carrier.
3. The device of claim 2 further comprising at least one activation string operably connected to said at least one delivery arm such that pulling said at least one activation string causes said at least one delivery arm to pivot.
4. A device useable to support a prolapsed valve leaflet, comprising:
a support;
an attachment mechanism, operably attached to the support member, and useable to attach the support member to a prolapsed valve leaflet.
5. The device of claim 4 wherein said support comprises a first part pivotally connected to a second part.
6. The device of claim 5 further comprising a hinge pivotally connecting said first and second parts.
7. The device of claim 4 wherein said support comprises at least one elongate beam.
8. The device of claim 4 wherein said support comprises Nitonol.
9. The device of claim 4 wherein said support comprises an open network of support members.
10. The device of claim 4 wherein said support comprises a covered network of support members.
11. The device of claim 4 wherein said support comprises a substrate.
12. The device of claim 11 wherein said substrate is curved, forming a concave side and a convex side, the concave side facing a downstream direction when the device is attached to a prolapsed valve leaflet.
13. The device of claim 11 wherein said substrate is attachable to an upstream side of a prolapsed valve.
14. The device of claim 11 wherein said substrate is attachable to a downstream side of a prolapsed valve.
15. The device of claim 4 wherein said attachment mechanism comprises barbs.
16. The device of claim 4 wherein said attachment mechanism comprises staples.
17. The device of claim 4 wherein said attachment mechanism protrudes from an upstream side of said support.
18. The device of claim 4 wherein said attachment mechanism protrudes from a downstream side of said support.
19. The device of claim 4 wherein said support comprises an upstream member constructed and arranged for placement on an upstream side of a prolapsed valve leaflet, and a downstream member constructed and arranged for placement on a downstream side of the prolapsed valve leaflet.
20. The device of claim 19 wherein said attachment mechanism operably connects the upstream member to the downstream member, such that the prolapsed valve leaflet is sandwiched between the upstream member and the downstream member.
21. The device of claim 19 wherein said attachment mechanism comprises a magnetic field operably connecting the upstream member to the downstream member.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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US13/673,886 US20130073034A1 (en) | 2003-07-03 | 2012-11-09 | Leaflet Reinforcement For Regurgitant Valves |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/613,121 US8348963B2 (en) | 2002-07-03 | 2003-07-03 | Leaflet reinforcement for regurgitant valves |
US13/673,886 US20130073034A1 (en) | 2003-07-03 | 2012-11-09 | Leaflet Reinforcement For Regurgitant Valves |
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Application Number | Title | Priority Date | Filing Date |
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US10/613,121 Division US8348963B2 (en) | 2002-07-03 | 2003-07-03 | Leaflet reinforcement for regurgitant valves |
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US20130073034A1 true US20130073034A1 (en) | 2013-03-21 |
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US10/613,121 Active 2025-09-06 US8348963B2 (en) | 2002-07-03 | 2003-07-03 | Leaflet reinforcement for regurgitant valves |
US13/673,886 Abandoned US20130073034A1 (en) | 2003-07-03 | 2012-11-09 | Leaflet Reinforcement For Regurgitant Valves |
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US10/613,121 Active 2025-09-06 US8348963B2 (en) | 2002-07-03 | 2003-07-03 | Leaflet reinforcement for regurgitant valves |
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US11583396B2 (en) | 2009-12-04 | 2023-02-21 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US11839544B2 (en) | 2019-02-14 | 2023-12-12 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US11969346B2 (en) | 2021-01-29 | 2024-04-30 | Edwards Lifesciences Corporation | Heart valve coaptation device |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0850607A1 (en) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
WO1999000059A1 (en) | 1997-06-27 | 1999-01-07 | The Trustees Of Columbia University In The City Of New York | Method and apparatus for circulatory valve repair |
FR2768324B1 (en) | 1997-09-12 | 1999-12-10 | Jacques Seguin | SURGICAL INSTRUMENT FOR PERCUTANEOUSLY FIXING TWO AREAS OF SOFT TISSUE, NORMALLY MUTUALLY REMOTE, TO ONE ANOTHER |
US10327743B2 (en) * | 1999-04-09 | 2019-06-25 | Evalve, Inc. | Device and methods for endoscopic annuloplasty |
ATE484241T1 (en) | 1999-04-09 | 2010-10-15 | Evalve Inc | METHOD AND DEVICE FOR HEART VALVE REPAIR |
US7563267B2 (en) | 1999-04-09 | 2009-07-21 | Evalve, Inc. | Fixation device and methods for engaging tissue |
US7811296B2 (en) | 1999-04-09 | 2010-10-12 | Evalve, Inc. | Fixation devices for variation in engagement of tissue |
US8216256B2 (en) | 1999-04-09 | 2012-07-10 | Evalve, Inc. | Detachment mechanism for implantable fixation devices |
US20040044350A1 (en) * | 1999-04-09 | 2004-03-04 | Evalve, Inc. | Steerable access sheath and methods of use |
US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6733525B2 (en) | 2001-03-23 | 2004-05-11 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of use |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US6575971B2 (en) | 2001-11-15 | 2003-06-10 | Quantum Cor, Inc. | Cardiac valve leaflet stapler device and methods thereof |
US6997950B2 (en) * | 2003-01-16 | 2006-02-14 | Chawla Surendra K | Valve repair device |
US10646229B2 (en) | 2003-05-19 | 2020-05-12 | Evalve, Inc. | Fixation devices, systems and methods for engaging tissue |
EP2308425B2 (en) | 2004-03-11 | 2023-10-18 | Percutaneous Cardiovascular Solutions Pty Limited | Percutaneous Heart Valve Prosthesis |
CA2566666C (en) | 2004-05-14 | 2014-05-13 | Evalve, Inc. | Locking mechanisms for fixation devices and methods of engaging tissue |
AU2005284739B2 (en) | 2004-09-14 | 2011-02-24 | Edwards Lifesciences Ag | Device and method for treatment of heart valve regurgitation |
US8052592B2 (en) | 2005-09-27 | 2011-11-08 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
US7635329B2 (en) * | 2004-09-27 | 2009-12-22 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
CA2597066C (en) | 2005-02-07 | 2014-04-15 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
US8470028B2 (en) | 2005-02-07 | 2013-06-25 | Evalve, Inc. | Methods, systems and devices for cardiac valve repair |
EP2649964B1 (en) * | 2005-02-28 | 2019-07-24 | Medtentia International Ltd Oy | Devices for improving the function of a heart valve |
SE531468C2 (en) * | 2005-04-21 | 2009-04-14 | Edwards Lifesciences Ag | An apparatus for controlling blood flow |
BRPI0617066A2 (en) | 2005-09-07 | 2011-07-12 | Medtentia Ab | heart valve function enhancement devices and method |
US8092525B2 (en) * | 2005-10-26 | 2012-01-10 | Cardiosolutions, Inc. | Heart valve implant |
US8216302B2 (en) * | 2005-10-26 | 2012-07-10 | Cardiosolutions, Inc. | Implant delivery and deployment system and method |
US8778017B2 (en) * | 2005-10-26 | 2014-07-15 | Cardiosolutions, Inc. | Safety for mitral valve implant |
US7785366B2 (en) | 2005-10-26 | 2010-08-31 | Maurer Christopher W | Mitral spacer |
US8449606B2 (en) * | 2005-10-26 | 2013-05-28 | Cardiosolutions, Inc. | Balloon mitral spacer |
US8852270B2 (en) | 2007-11-15 | 2014-10-07 | Cardiosolutions, Inc. | Implant delivery system and method |
US9259317B2 (en) | 2008-06-13 | 2016-02-16 | Cardiosolutions, Inc. | System and method for implanting a heart implant |
US7797607B2 (en) * | 2005-12-27 | 2010-09-14 | Lg Electronics, Inc. | DTV transmitter and method of coding main and enhanced data in DTV transmitter |
US8932348B2 (en) | 2006-05-18 | 2015-01-13 | Edwards Lifesciences Corporation | Device and method for improving heart valve function |
WO2007140470A2 (en) * | 2006-06-01 | 2007-12-06 | Edwards Lifesciences Corporation | Prosthetic insert for improving heart valve function |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
US8480730B2 (en) * | 2007-05-14 | 2013-07-09 | Cardiosolutions, Inc. | Solid construct mitral spacer |
US8597347B2 (en) | 2007-11-15 | 2013-12-03 | Cardiosolutions, Inc. | Heart regurgitation method and apparatus |
US20100121437A1 (en) * | 2008-04-16 | 2010-05-13 | Cardiovascular Technologies, Llc | Transvalvular intraannular band and chordae cutting for ischemic and dilated cardiomyopathy |
US11083579B2 (en) | 2008-04-16 | 2021-08-10 | Heart Repair Technologies, Inc. | Transvalvular intraanular band and chordae cutting for ischemic and dilated cardiomyopathy |
US20100131057A1 (en) | 2008-04-16 | 2010-05-27 | Cardiovascular Technologies, Llc | Transvalvular intraannular band for aortic valve repair |
US20100121435A1 (en) | 2008-04-16 | 2010-05-13 | Cardiovascular Technologies, Llc | Percutaneous transvalvular intrannular band for mitral valve repair |
US8262725B2 (en) * | 2008-04-16 | 2012-09-11 | Cardiovascular Technologies, Llc | Transvalvular intraannular band for valve repair |
US10456259B2 (en) | 2008-04-16 | 2019-10-29 | Heart Repair Technologies, Inc. | Transvalvular intraannular band for mitral valve repair |
US11013599B2 (en) | 2008-04-16 | 2021-05-25 | Heart Repair Technologies, Inc. | Percutaneous transvalvular intraannular band for mitral valve repair |
US20090276040A1 (en) | 2008-05-01 | 2009-11-05 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
US8591460B2 (en) | 2008-06-13 | 2013-11-26 | Cardiosolutions, Inc. | Steerable catheter and dilator and system and method for implanting a heart implant |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
US20100023118A1 (en) * | 2008-07-24 | 2010-01-28 | Edwards Lifesciences Corporation | Method and apparatus for repairing or replacing chordae tendinae |
US8778016B2 (en) * | 2008-08-14 | 2014-07-15 | Edwards Lifesciences Corporation | Method and apparatus for repairing or replacing chordae tendinae |
CN102438546B (en) | 2008-11-21 | 2015-07-15 | 经皮心血管解决方案公司 | Heart valve prosthesis |
EP2477555B1 (en) | 2009-09-15 | 2013-12-25 | Evalve, Inc. | Device for cardiac valve repair |
US20110077733A1 (en) * | 2009-09-25 | 2011-03-31 | Edwards Lifesciences Corporation | Leaflet contacting apparatus and method |
CA3035048C (en) | 2010-12-23 | 2021-05-04 | Mark Deem | System for mitral valve repair and replacement |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9289282B2 (en) | 2011-05-31 | 2016-03-22 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
AU2012272855C1 (en) | 2011-06-21 | 2018-04-05 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US8945177B2 (en) | 2011-09-13 | 2015-02-03 | Abbott Cardiovascular Systems Inc. | Gripper pusher mechanism for tissue apposition systems |
US10016271B2 (en) | 2011-10-19 | 2018-07-10 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
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EP2750630B1 (en) | 2011-10-19 | 2021-06-30 | Twelve, Inc. | Device for heart valve replacement |
EP2591754B1 (en) | 2011-11-10 | 2015-02-25 | Medtentia International Ltd Oy | A device and a method for improving the function of a heart valve |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US20140067048A1 (en) * | 2012-09-06 | 2014-03-06 | Edwards Lifesciences Corporation | Heart Valve Sealing Devices |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US9289297B2 (en) | 2013-03-15 | 2016-03-22 | Cardiosolutions, Inc. | Mitral valve spacer and system and method for implanting the same |
US9232998B2 (en) | 2013-03-15 | 2016-01-12 | Cardiosolutions Inc. | Trans-apical implant systems, implants and methods |
ES2908132T3 (en) | 2013-05-20 | 2022-04-27 | Edwards Lifesciences Corp | Prosthetic Heart Valve Delivery Apparatus |
CN108294846A (en) | 2013-05-20 | 2018-07-20 | 托尔福公司 | Implantable cardiac valve device, mitral valve repair device and related system and method |
JP6731339B2 (en) | 2013-06-14 | 2020-07-29 | カーディオソリューションズ インコーポレイテッドCardiosolutions, Inc. | Mitral valve spacer and implantation system and method thereof |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
CN106163453B (en) * | 2014-02-14 | 2018-05-29 | 爱德华兹生命科学公司 | Percutaneous leaflet increase |
US10390943B2 (en) | 2014-03-17 | 2019-08-27 | Evalve, Inc. | Double orifice device for transcatheter mitral valve replacement |
US9572666B2 (en) | 2014-03-17 | 2017-02-21 | Evalve, Inc. | Mitral valve fixation device removal devices and methods |
US10188392B2 (en) | 2014-12-19 | 2019-01-29 | Abbott Cardiovascular Systems, Inc. | Grasping for tissue repair |
US10524912B2 (en) | 2015-04-02 | 2020-01-07 | Abbott Cardiovascular Systems, Inc. | Tissue fixation devices and methods |
US10376673B2 (en) | 2015-06-19 | 2019-08-13 | Evalve, Inc. | Catheter guiding system and methods |
US10238494B2 (en) | 2015-06-29 | 2019-03-26 | Evalve, Inc. | Self-aligning radiopaque ring |
US10667815B2 (en) | 2015-07-21 | 2020-06-02 | Evalve, Inc. | Tissue grasping devices and related methods |
US10413408B2 (en) | 2015-08-06 | 2019-09-17 | Evalve, Inc. | Delivery catheter systems, methods, and devices |
CN107920895B (en) * | 2015-08-21 | 2020-06-26 | 托尔福公司 | Implantable heart valve devices, mitral valve repair devices, and associated systems and methods |
US10238495B2 (en) | 2015-10-09 | 2019-03-26 | Evalve, Inc. | Delivery catheter handle and methods of use |
EP3367971B1 (en) | 2015-10-27 | 2023-12-27 | Xeltis AG | Medical device using bioabsorbable material |
CN109069272A (en) | 2016-04-29 | 2018-12-21 | 美敦力瓦斯科尔勒公司 | Prosthetic heart valve equipment and associated system and method with the anchor log with tether |
US20200146854A1 (en) * | 2016-05-16 | 2020-05-14 | Elixir Medical Corporation | Methods and devices for heart valve repair |
CN106512107A (en) * | 2016-07-04 | 2017-03-22 | 中国人民解放军第四军医大学 | Peritoneoscope aspirator and mouth structure |
US10736632B2 (en) | 2016-07-06 | 2020-08-11 | Evalve, Inc. | Methods and devices for valve clip excision |
US11071564B2 (en) | 2016-10-05 | 2021-07-27 | Evalve, Inc. | Cardiac valve cutting device |
US10363138B2 (en) | 2016-11-09 | 2019-07-30 | Evalve, Inc. | Devices for adjusting the curvature of cardiac valve structures |
US10398553B2 (en) | 2016-11-11 | 2019-09-03 | Evalve, Inc. | Opposing disk device for grasping cardiac valve tissue |
US10426616B2 (en) | 2016-11-17 | 2019-10-01 | Evalve, Inc. | Cardiac implant delivery system |
US10779837B2 (en) | 2016-12-08 | 2020-09-22 | Evalve, Inc. | Adjustable arm device for grasping tissues |
US10314586B2 (en) | 2016-12-13 | 2019-06-11 | Evalve, Inc. | Rotatable device and method for fixing tricuspid valve tissue |
EP3558166A4 (en) | 2016-12-22 | 2021-03-31 | Heart Repair Technologies, Inc. | Percutaneous delivery systems for anchoring an implant in a cardiac valve annulus |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US11065119B2 (en) | 2017-05-12 | 2021-07-20 | Evalve, Inc. | Long arm valve repair clip |
US10842619B2 (en) | 2017-05-12 | 2020-11-24 | Edwards Lifesciences Corporation | Prosthetic heart valve docking assembly |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
WO2019144121A1 (en) | 2018-01-22 | 2019-07-25 | Edwards Lifesciences Corporation | Heart shape preserving anchor |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6565581B1 (en) * | 1996-09-16 | 2003-05-20 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US6629534B1 (en) * | 1999-04-09 | 2003-10-07 | Evalve, Inc. | Methods and apparatus for cardiac valve repair |
US6752813B2 (en) * | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US15192A (en) * | 1856-06-24 | Tubular | ||
US5046497A (en) * | 1986-11-14 | 1991-09-10 | Millar Instruments, Inc. | Structure for coupling a guidewire and a catheter |
US5071407A (en) * | 1990-04-12 | 1991-12-10 | Schneider (U.S.A.) Inc. | Radially expandable fixation member |
US5221261A (en) * | 1990-04-12 | 1993-06-22 | Schneider (Usa) Inc. | Radially expandable fixation member |
US5411552A (en) * | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
DK124690D0 (en) * | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION |
US5397351A (en) * | 1991-05-13 | 1995-03-14 | Pavcnik; Dusan | Prosthetic valve for percutaneous insertion |
US5258023A (en) * | 1992-02-12 | 1993-11-02 | Reger Medical Development, Inc. | Prosthetic heart valve |
IN175399B (en) * | 1992-03-26 | 1995-06-10 | Kalke Mhatre Associates | |
US5409019A (en) * | 1992-10-30 | 1995-04-25 | Wilk; Peter J. | Coronary artery by-pass method |
US5429144A (en) * | 1992-10-30 | 1995-07-04 | Wilk; Peter J. | Coronary artery by-pass method |
US5797960A (en) * | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
US5496329A (en) * | 1993-09-08 | 1996-03-05 | Alpha Surgical, Inc. | Method and apparatus for implanting a medical ventilation tube |
US5725552A (en) * | 1994-07-08 | 1998-03-10 | Aga Medical Corporation | Percutaneous catheter directed intravascular occlusion devices |
US6123715A (en) * | 1994-07-08 | 2000-09-26 | Amplatz; Curtis | Method of forming medical devices; intravascular occlusion devices |
US5846261A (en) * | 1994-07-08 | 1998-12-08 | Aga Medical Corp. | Percutaneous catheter directed occlusion devices |
IL118149A0 (en) * | 1996-05-05 | 1996-09-12 | Rdc Rafael Dev Corp | Method for producing heart valves and heart valves produced by the method |
US6293955B1 (en) * | 1996-09-20 | 2001-09-25 | Converge Medical, Inc. | Percutaneous bypass graft and securing system |
AU4489197A (en) * | 1996-09-20 | 1998-04-14 | Sid D. Fleischman | Radially expanding prostheses and systems for their deployment |
US5972017A (en) * | 1997-04-23 | 1999-10-26 | Vascular Science Inc. | Method of installing tubular medical graft connectors |
US6120432A (en) * | 1997-04-23 | 2000-09-19 | Vascular Science Inc. | Medical grafting methods and apparatus |
US6036702A (en) * | 1997-04-23 | 2000-03-14 | Vascular Science Inc. | Medical grafting connectors and fasteners |
NL1004827C2 (en) * | 1996-12-18 | 1998-06-19 | Surgical Innovations Vof | Device for regulating blood circulation. |
EP0850607A1 (en) * | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
US5928224A (en) * | 1997-01-24 | 1999-07-27 | Hearten Medical, Inc. | Device for the treatment of damaged heart valve leaflets and methods of using the device |
US6106497A (en) * | 1997-01-31 | 2000-08-22 | Medical Instrument Development Laboratories | System and method for preventing an air embolism in a surgical procedure |
US5957949A (en) * | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
US6074416A (en) * | 1997-10-09 | 2000-06-13 | St. Jude Medical Cardiovascular Group, Inc. | Wire connector structures for tubular grafts |
US5944738A (en) * | 1998-02-06 | 1999-08-31 | Aga Medical Corporation | Percutaneous catheter directed constricting occlusion device |
US6074418A (en) * | 1998-04-20 | 2000-06-13 | St. Jude Medical, Inc. | Driver tool for heart valve prosthesis fasteners |
JP4399585B2 (en) * | 1998-06-02 | 2010-01-20 | クック インコーポレイティド | Multi-sided medical device |
US7452371B2 (en) * | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US6165183A (en) * | 1998-07-15 | 2000-12-26 | St. Jude Medical, Inc. | Mitral and tricuspid valve repair |
US6641610B2 (en) | 1998-09-10 | 2003-11-04 | Percardia, Inc. | Valve designs for left ventricular conduits |
US6334873B1 (en) * | 1998-09-28 | 2002-01-01 | Autogenics | Heart valve having tissue retention with anchors and an outer sheath |
US6475239B1 (en) * | 1998-10-13 | 2002-11-05 | Sulzer Carbomedics Inc. | Method for making polymer heart valves with leaflets having uncut free edges |
US6113612A (en) * | 1998-11-06 | 2000-09-05 | St. Jude Medical Cardiovascular Group, Inc. | Medical anastomosis apparatus |
US6336937B1 (en) * | 1998-12-09 | 2002-01-08 | Gore Enterprise Holdings, Inc. | Multi-stage expandable stent-graft |
DE60037309T2 (en) * | 1999-01-26 | 2008-11-27 | Edwards Lifesciences Corp., Irvine | FLEXIBLE HEART FLAP |
US6425916B1 (en) * | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
DE60017095T2 (en) * | 1999-02-22 | 2005-12-15 | University Of Miami, Miami | FLAP FOR A TINY CAPSULORHEXIS |
WO2000053104A1 (en) * | 1999-03-09 | 2000-09-14 | St. Jude Medical Cardiovascular Group, Inc. | Medical grafting methods and apparatus |
US6428550B1 (en) * | 1999-05-18 | 2002-08-06 | Cardica, Inc. | Sutureless closure and deployment system for connecting blood vessels |
US6494889B1 (en) * | 1999-09-01 | 2002-12-17 | Converge Medical, Inc. | Additional sutureless anastomosis embodiments |
US6440164B1 (en) * | 1999-10-21 | 2002-08-27 | Scimed Life Systems, Inc. | Implantable prosthetic valve |
US6458153B1 (en) | 1999-12-31 | 2002-10-01 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US7195641B2 (en) * | 1999-11-19 | 2007-03-27 | Advanced Bio Prosthetic Surfaces, Ltd. | Valvular prostheses having metal or pseudometallic construction and methods of manufacture |
US6423090B1 (en) * | 2000-02-11 | 2002-07-23 | Advanced Cardiovascular Systems, Inc. | Stent pattern with staged expansion |
US6454799B1 (en) * | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US6358277B1 (en) * | 2000-06-21 | 2002-03-19 | The International Heart Institute Of Montana Foundation | Atrio-ventricular valvular device |
US6676698B2 (en) * | 2000-06-26 | 2004-01-13 | Rex Medicol, L.P. | Vascular device with valve for approximating vessel wall |
US6419696B1 (en) * | 2000-07-06 | 2002-07-16 | Paul A. Spence | Annuloplasty devices and related heart valve repair methods |
US20020023300A1 (en) * | 2000-07-11 | 2002-02-28 | Stanley Arthur Lagrant | Liquid-filled, tube style, shock inverter/seat cushion |
ATE346571T1 (en) | 2000-09-21 | 2006-12-15 | St Jude Medical | VALVE PROSTHESIS WITH LEAF ELEMENTS MADE OF REINFORCED PLASTIC |
FR2816826B1 (en) | 2000-11-17 | 2003-09-26 | Laurent Jacquemin | DEVICE FOR CORRECTING THE SHRINKAGE OF THE AORTIC VALVE OF MAN WITHOUT OPENING OR STOPPING THE HEART |
US6494909B2 (en) * | 2000-12-01 | 2002-12-17 | Prodesco, Inc. | Endovascular valve |
US6454798B1 (en) * | 2000-12-21 | 2002-09-24 | Sulzer Carbomedics Inc. | Polymer heart valve with helical coaption surface |
US6503272B2 (en) * | 2001-03-21 | 2003-01-07 | Cordis Corporation | Stent-based venous valves |
-
2003
- 2003-07-03 US US10/613,121 patent/US8348963B2/en active Active
-
2012
- 2012-11-09 US US13/673,886 patent/US20130073034A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6565581B1 (en) * | 1996-09-16 | 2003-05-20 | Origin Medsystems, Inc. | Apparatus and method for performing an anastomosis |
US6629534B1 (en) * | 1999-04-09 | 2003-10-07 | Evalve, Inc. | Methods and apparatus for cardiac valve repair |
US6752813B2 (en) * | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
Cited By (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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