US20140276403A1 - Ischemic stroke device - Google Patents
Ischemic stroke device Download PDFInfo
- Publication number
- US20140276403A1 US20140276403A1 US13/801,979 US201313801979A US2014276403A1 US 20140276403 A1 US20140276403 A1 US 20140276403A1 US 201313801979 A US201313801979 A US 201313801979A US 2014276403 A1 US2014276403 A1 US 2014276403A1
- Authority
- US
- United States
- Prior art keywords
- expandable member
- obstruction
- proximal
- interstices
- distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22031—Gripping instruments, e.g. forceps, for removing or smashing calculi
- A61B17/22032—Gripping instruments, e.g. forceps, for removing or smashing calculi having inflatable gripping elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
- A61B2017/2212—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop
Definitions
- the present invention relates to an apparatus and method for increasing blood flow through an obstructed blood vessel and, more particularly relates to an apparatus and method for removal of at least a portion of an obstruction such as a clot from an obstructed blood vessel for treatment of ischemic stroke.
- a common treatment for ischemic stroke is the use of a thrombectomy device to physically remove an obstruction such as a blood clot from the affected artery.
- a thrombectomy device typically is advanced through a microcatheter into the vasculature, and is deployed into an obstruction or clot in the vasculature by pulling back on the microcatheter, allowing the thrombectomy device to capture at least a portion of the obstruction or clot, and the thrombectomy device is then retrieved by withdrawing the thrombectomy device into a catheter such as a guide catheter or an intermediate catheter.
- a balloon guide catheter or aspiration catheter may be used. Aspiration is performed by attaching a syringe to a proximal end of the guide catheter and pulling a vacuum in the syringe, while simultaneously pulling the retrieving the thrombectomy device and the captured portion of the obstruction or clot into the guide catheter.
- a balloon guide may be inflated just prior to retrieval of the thrombectomy device and the captured portion of the obstruction or clot in order to arrest blood flow. The thrombectomy device with the captured portion of the obstruction or clot is then pulled back into the balloon guide catheter.
- One embolic protection device includes inner and outer tubular members and a flexible everting filter portion that is attached at one end to a distal end of the inner tubular member, and that is attached at a second end to a distal end of the outer tubular member, so that the inner and outer tubular members are movable relative to one another to position the filter portion within the body vessel.
- the filter portion is movable from a collapsed, everted configuration to an expanded, generally non-everted deployed configuration.
- the filter portion expands radially outward to engage the filter body with an enclosing vessel wall, and also allows the passage of blood cells, while preventing the passage of captured emboli or thrombi through the filter portion.
- Another similar invertible filter includes a guiding member configured to slidably engage a tubular filter portion that extends distally from the guiding member and is configured to evert to form a concave shape for capturing emboli, while allowing blood cells to pass through the filter portion.
- Another type of device for treating a vascular condition includes a graft, and first and second support members such as stents attached to distal and proximal regions of the graft.
- the first and second stents are deployed distally and proximally of a vascular condition, and the graft can be everted to form a pocket to trap emboli during treatment of the vascular condition.
- Another device includes a capturing section configured that can be inverted within a translating section by proximal movement of a leading wire when an open proximal end of the translating section engages resistance, and the size of the capturing section is reduced to enable the capturing section to re-enter a catheter.
- Another device for increasing blood flow through an obstructed blood vessel includes an expandable member that is positioned within a blood vessel and radially adjacent to at least a portion of an obstruction, and that is expanded to bring at least a portion of the expandable member into contact with the obstruction.
- the expandable member is made of a mesh having a plurality of interstices that allow one or more fragments of the obstruction to pass into and be retained within the expandable member when an outward radial force is exerted on the obstruction by the expandable member.
- the present invention meets these and other needs.
- the present invention provides for an apparatus and method for removal of at least a portion of an obstruction such as a clot from an obstructed blood vessel for treatment of a condition of a patient's vasculature such as ischemic stroke.
- the apparatus and method of the invention helps to reduce the risk of losing one or more pieces of an obstruction such as a clot during a thrombectomy procedure by providing a first or proximal expandable member that functions as a cover element that can evert to enfold and enclose a second or distal expandable member used to secure the obstruction or clot prior to pulling the secured obstruction or clot into a catheter for removal from the patient's vasculature.
- the first or proximal expandable member covers over not only the captured obstruction or clot, but also portions of the obstruction or clot which may be only partially captured, such as a portion of the obstruction stuck to or extending from the outside of the second or distal expandable member, to help to prevent the clot from being scraped off when the clot is pulled into a catheter.
- the close proximity of the first and second expandable members also allows the captured obstruction or clot to be covered almost immediately, which also can help to reduce the possibility of fragmentation of the obstruction or clot.
- a telescoping support member connected to the first or proximal expandable member also allows a user to initiate the process of causing the first or proximal expandable member to evert to enfold and enclose the second or distal expandable member used to secure the obstruction or clot.
- the present invention accordingly provides for an apparatus and method for removal of at least a portion of an obstruction from an obstructed blood vessel for treatment of ischemic stroke.
- the apparatus includes a telescoping support member, a first or proximal expandable member connected to the telescoping support member, and a second or distal expandable member connected to the first or proximal expandable member.
- the telescoping support member includes an outer tubular shaft and an inner elongate member that extends through and is slidable within the outer tubular shaft.
- the first or proximal expandable member has a proximal end that is attached to a distal end of the outer tubular shaft of the telescoping support member, and a distal end of the first or proximal expandable member is attached to a distal portion of the inner elongate member.
- the first or proximal expandable member preferably has a radially compressed configuration and a radially expanded configuration, as well as a longitudinally extended configuration with proximal and distal ends of the first or proximal expandable member disposed at opposing ends of the first or proximal expandable member, and an everted configuration with the distal end of the first or proximal expandable member withdrawn within the tubular body of the first or proximal expandable member and adjacent to the proximal end of the first or proximal expandable member.
- the second or distal expandable member preferably has a closed distal end and a closed proximal end, and a tubular mesh body extending between the proximal and distal ends of the second or distal expandable member, and is configured to be deployed into an obstruction within the blood vessel.
- the closed proximal end of the second or distal expandable member preferably also is permanently joined to the distal end of the inner elongate member of the telescoping support member.
- the second or distal expandable member also preferably has a radially compressed configuration and a radially expanded configuration, and the tubular mesh body of the second or distal expandable member preferably is configured to radially expand into contact with at least a portion of the obstruction or clot such that a portion of the obstruction or clot is dislodged to enhance blood flow through the blood vessel.
- the tubular mesh body includes a plurality of interstices, at least a portion of which are adapted to allow passage of at least one dislodged portion of the obstruction therethrough in a radial direction into the tubular mesh body.
- the tubular body of the first or proximal expandable member includes a plurality strands defining a plurality of interstices therebetween.
- the tubular body of the first or proximal expandable member includes a radiopaque band permanently attached to the distal end of the first or proximal expandable member.
- the tubular mesh body of the second or distal expandable member comprises a plurality of strands, and the plurality of strands may form first and second meshes.
- each of the plurality of strands is oriented in at least one of a helical, longitudinal, and radial direction with respect to the tubular mesh body.
- the second or distal expandable member is at least partially constructed of a self-expanding material, and the second or distal expandable member is configured to dislodge the obstruction by fracturing a portion of the obstruction or by extruding a portion of the obstruction.
- the second or distal expandable member includes at least one radiopaque portion.
- the second or distal expandable member is at least partially adapted to elute a pharmaceutical agent.
- the pharmaceutical agent is adapted to at least partially lyse the at least one fragment.
- the tubular mesh body of the second or distal expandable member includes a distal portion and a proximal portion, the distal portion of the tubular mesh body being formed of a first mesh, and the proximal portion of the tubular mesh body being made of a second mesh having a plurality of second interstices, at least one of the second interstices being adapted to selectively allow passage of at least one fragment therethrough.
- the first mesh is formed integrally with the second mesh.
- at least one of the first interstices is defined by a plurality of first strands, and at least one of the plurality of first strands is adapted to penetrate into the obstruction to longitudinally separate the at least one fragment from a remaining portion of the obstruction.
- At least one of the second interstices is defined by a plurality of second strands, at least one of the plurality of second strands is adapted to break the at least one fragment into a plurality of subfragments, and at least one of the second interstices is adapted to selectively allow passage therethrough of at least one subfragment to release the at least one subfragment from the second or distal expandable member.
- at least one of the plurality of second interstices is smaller than at least one of the plurality of first interstices.
- a size of at least one of the plurality of second interstices is chosen on the basis of an allowable particulate size of the blood vessel.
- the tubular mesh body of the second or distal expandable member is configured to compress at least a portion of the obstruction against a vessel wall of the blood vessel.
- movement of the inner elongate member in a proximal direction relative to the outer tubular shaft of the telescoping support member moves the first or proximal expandable member between the longitudinally extended configuration and the everted configuration such that the first or proximal expandable member covers, enfolds or envelopes the second or distal expandable member.
- FIG. 1 is an elevational, schematic diagram of the apparatus of the invention disposed within a patient's vasculature, showing the first and second expandable members in radially expanded configurations within the vasculature, with an obstruction or clot captured within the second or distal expandable member, according to the invention.
- FIG. 2 is an elevational, schematic diagram similar to FIG. 1 , showing the first or proximal expandable member beginning to evert to enfold and cover the second or distal expandable member as the second or distal expandable member is drawn into the first or proximal expandable member.
- FIG. 3 is an elevational, schematic diagram similar to FIG. 2 , showing the first or proximal expandable member everted to enfold and cover the second or distal expandable member, which has been drawn into the first or proximal expandable member.
- FIG. 4 is an enlarged cross-sectional view similar to FIG. 3 .
- FIG. 5 is an elevational, schematic diagram similar to FIG. 3 , showing the first and second expandable members with the captured obstruction or clot being retrieved and withdrawn into a catheter.
- the present invention provides for an apparatus 10 having a proximal end 12 and a distal end 14 , for removal of at least a portion of an obstruction 16 , such as a clot, for example, from an obstructed blood vessel in a patient's vasculature 18 , such as for treatment of ischemic stroke, for example.
- an obstruction 16 such as a clot, for example, from an obstructed blood vessel in a patient's vasculature 18 , such as for treatment of ischemic stroke, for example.
- the apparatus includes a telescoping support member 20 , including an outer tubular shaft 22 having a distal end 24 , and an inner elongate member or core advancement wire 26 having a distal end 28 and a proximal portion 30 , and extending through the outer tubular shaft and slidable within the outer tubular shaft.
- the apparatus also includes a first, proximal expandable member or cover element 32 having a proximal end 34 and a distal end 36 , and a tubular body 38 extending between the proximal and distal ends of the first or proximal expandable member.
- the proximal end of the first or proximal expandable member is preferably permanently attached to the distal end of the outer tubular shaft of the telescoping support member, and the distal end of the first or proximal expandable member is preferably permanently attached to a distal portion 40 of the inner elongate member or core advancement wire.
- the first or proximal expandable member has a radially expanded configuration configured to engage the inner surface of a blood vessel in the patient's vasculature, as shown in FIGS. 1-4 , and a radially compressed configuration, such as when the first or proximal expandable member is disposed within and constrained by an introducer or delivery catheter 42 having an inner lumen (not shown).
- the first or proximal expandable member preferably is dimensioned to fit within the inner lumen of the catheter in the radially compressed configuration, and is configured to be constrained from expanding when the first or proximal expandable member is contained within the catheter.
- the first or proximal expandable member in the radially expanded configuration, preferably also has a longitudinally extended configuration with the proximal and distal ends of the first or proximal expandable member disposed at opposing ends of the first or proximal expandable member, and an everted configuration, best shown fully in FIG. 4 , with the distal end of the first or proximal expandable member withdrawn within the tubular body of the first or proximal expandable member adjacent to the proximal end of the first or proximal expandable member.
- the tubular body of the first or proximal expandable member preferably includes a plurality strands of material 48 forming a proximal braided portion of the apparatus, defining a plurality of interstices 50 therebetween.
- the first or proximal expandable member also preferably includes at least one radiopaque portion, such as a radiopaque band 52 that is permanently attached to the distal end of the first or proximal expandable member.
- the apparatus also includes a second, distal expandable member 54 at the distal end of the apparatus, that is configured to be deployed into an obstruction or clot within the blood vessel in the patient's vasculature.
- the second or distal expandable member preferably includes a closed distal end 56 a closed proximal end 58 , and a tubular mesh body 60 extending between the proximal and distal ends of the second or distal expandable member.
- the closed proximal end of the second or distal expandable member preferably is permanently joined to the distal end of the inner elongate member of the telescoping support member, such as by soldering, for example, although the second or distal expandable member may alternatively be permanently joined to the distal end of the inner elongate member of the telescoping support member by other similar suitable means, such as by adhesive or by heat shrinkable tubing, or combinations thereof, for example.
- the tubular mesh body of the second, distal expandable member preferably is configured to radially expand into contact with at least a portion of the obstruction or clot in the blood vessel, such that a portion of the obstruction is dislodged to enhance blood flow through the blood vessel.
- the tubular mesh body preferably includes a plurality of interstices 62 , and at least a portion of the interstices preferably are configured to allow passage of at least one dislodged portion of the obstruction therethrough in a radial direction into the tubular mesh body.
- the tubular mesh body can be formed to include a plurality of strands 63 forming first and second meshes, wherein each of the strands may be oriented in at least one of a helical, longitudinal, and radial direction with respect to the tubular mesh body.
- the second or distal expandable member is configured to dislodge the obstruction or clot by fracturing a portion of the obstruction, by extruding a portion of the obstruction, or a combination thereof.
- the second or distal expandable member is at least partially constructed of a superelastic and/or self-expanding material, such as a nickel-titanium alloy which has been memory-shaped into an expanded condition and is compressed into a collapsed condition before use.
- the second or distal expandable member is constrained in the compressed condition by the introducer or delivery catheter, and preferably self-expands into the expanded condition upon removal from the introducer or delivery catheter.
- the second or distal expandable member may also include one or more radiopaque portions, such as one or more additional radiopaque bands, for example.
- the second or distal expandable member is at least partially adapted to elute a pharmaceutical agent, such as a pharmaceutical agent designed to at least partially lyse the obstruction or fragment of the obstruction.
- the tubular mesh body may include a first mesh in a distal portion of the tubular mesh body having a plurality of first interstices, and a second mesh in a proximal portion of the tubular mesh body being made of having a plurality of second interstices, with at least one of the second interstices being configured to selectively allow passage of at least one fragment therethrough.
- the first mesh can be formed integrally with the second mesh, for example.
- At least one of the first interstices may be defined by a plurality of first strands, in which case at least one of the plurality of first strands may be adapted to penetrate into the obstruction to longitudinally separate the at least one fragment from a remaining portion of the obstruction.
- At least one of the second interstices may be defined by a plurality of second strands, in which case at least one of the plurality of second strands may be adapted to break one or more fragments of the obstruction or clot into a plurality of subfragments, and at least one of the second interstices may be adapted to selectively allow passage of at least one subfragment therethrough to be released from the second or distal expandable member.
- one or more of the plurality of second interstices can be smaller than one or more of the plurality of first interstices, and the size of one or more of the plurality of second interstices may be chosen on the basis of an allowable particulate size of the blood vessel.
- the tubular mesh body may also be configured to compress at least a portion of the obstruction against a vessel wall of the blood vessel
- the proximal braided portion starts to evert, initiating covering the distal element, much like pulling a sock over a foot, so that movement of the inner elongate member in a proximal direction relative to the outer tubular shaft of the telescoping support member moves the first or proximal expandable member between the longitudinally extended configuration and the everted configuration, so that the first or proximal expandable member covers, envelopes or enfolds the second or distal expandable member as shown in FIG.
- any of the obstruction that may be only partially captured in the second or distal expandable member such as a portion of the obstruction stuck to or extending from the outside of the second or distal expandable member, for example, so that the second or distal expandable member and captured obstruction material can be withdrawn and retrieved into a catheter, as is illustrated in FIG. 5 .
Abstract
Description
- The present invention relates to an apparatus and method for increasing blood flow through an obstructed blood vessel and, more particularly relates to an apparatus and method for removal of at least a portion of an obstruction such as a clot from an obstructed blood vessel for treatment of ischemic stroke.
- A common treatment for ischemic stroke is the use of a thrombectomy device to physically remove an obstruction such as a blood clot from the affected artery. One such thrombectomy device typically is advanced through a microcatheter into the vasculature, and is deployed into an obstruction or clot in the vasculature by pulling back on the microcatheter, allowing the thrombectomy device to capture at least a portion of the obstruction or clot, and the thrombectomy device is then retrieved by withdrawing the thrombectomy device into a catheter such as a guide catheter or an intermediate catheter. To prevent the loss of the captured portion of the obstruction or clot when the thrombectomy device is being retrieved, a balloon guide catheter or aspiration catheter may be used. Aspiration is performed by attaching a syringe to a proximal end of the guide catheter and pulling a vacuum in the syringe, while simultaneously pulling the retrieving the thrombectomy device and the captured portion of the obstruction or clot into the guide catheter. A balloon guide may be inflated just prior to retrieval of the thrombectomy device and the captured portion of the obstruction or clot in order to arrest blood flow. The thrombectomy device with the captured portion of the obstruction or clot is then pulled back into the balloon guide catheter.
- One embolic protection device is known that includes inner and outer tubular members and a flexible everting filter portion that is attached at one end to a distal end of the inner tubular member, and that is attached at a second end to a distal end of the outer tubular member, so that the inner and outer tubular members are movable relative to one another to position the filter portion within the body vessel. The filter portion is movable from a collapsed, everted configuration to an expanded, generally non-everted deployed configuration. The filter portion expands radially outward to engage the filter body with an enclosing vessel wall, and also allows the passage of blood cells, while preventing the passage of captured emboli or thrombi through the filter portion.
- Another similar invertible filter is known that includes a guiding member configured to slidably engage a tubular filter portion that extends distally from the guiding member and is configured to evert to form a concave shape for capturing emboli, while allowing blood cells to pass through the filter portion.
- Another type of device for treating a vascular condition is known that includes a graft, and first and second support members such as stents attached to distal and proximal regions of the graft. The first and second stents are deployed distally and proximally of a vascular condition, and the graft can be everted to form a pocket to trap emboli during treatment of the vascular condition.
- Another device is known that includes a capturing section configured that can be inverted within a translating section by proximal movement of a leading wire when an open proximal end of the translating section engages resistance, and the size of the capturing section is reduced to enable the capturing section to re-enter a catheter.
- Another device for increasing blood flow through an obstructed blood vessel is known that includes an expandable member that is positioned within a blood vessel and radially adjacent to at least a portion of an obstruction, and that is expanded to bring at least a portion of the expandable member into contact with the obstruction. The expandable member is made of a mesh having a plurality of interstices that allow one or more fragments of the obstruction to pass into and be retained within the expandable member when an outward radial force is exerted on the obstruction by the expandable member.
- However, whenever a captured obstruction or clot is retrieved into any type of catheter there is always a risk of some or all of the obstruction or clot being released into a patient's vasculature. In many cases some or all of the obstruction or clot is captured on the outside of the thrombectomy device. As the thrombectomy device is pulled back into a catheter, some or all of the obstruction or clot may be scraped off, sending one or more pieces of the obstruction or clot downstream to another artery, after which one or more dislodged pieces of the obstruction or clot will then need to be removed, adding to the length of time and complexity of the procedure. Smaller pieces of the clot also may go further downstream to smaller vessels that are not accessible with current thrombectomy devices.
- It would be desirable to provide an apparatus and method for removal of at least a portion of an obstruction or clot from an obstructed blood vessel for treatment of ischemic stroke that provides a cover over the secured obstruction or clot prior to drawing the secured obstruction or clot into a catheter, in order to reduce the risk of the obstruction or clot being scraped off or otherwise losing one or more pieces of the obstruction or clot being retrieved during a thrombectomy procedure. The present invention meets these and other needs.
- Briefly and in general terms, the present invention provides for an apparatus and method for removal of at least a portion of an obstruction such as a clot from an obstructed blood vessel for treatment of a condition of a patient's vasculature such as ischemic stroke. The apparatus and method of the invention helps to reduce the risk of losing one or more pieces of an obstruction such as a clot during a thrombectomy procedure by providing a first or proximal expandable member that functions as a cover element that can evert to enfold and enclose a second or distal expandable member used to secure the obstruction or clot prior to pulling the secured obstruction or clot into a catheter for removal from the patient's vasculature. The first or proximal expandable member covers over not only the captured obstruction or clot, but also portions of the obstruction or clot which may be only partially captured, such as a portion of the obstruction stuck to or extending from the outside of the second or distal expandable member, to help to prevent the clot from being scraped off when the clot is pulled into a catheter. The close proximity of the first and second expandable members also allows the captured obstruction or clot to be covered almost immediately, which also can help to reduce the possibility of fragmentation of the obstruction or clot. A telescoping support member connected to the first or proximal expandable member also allows a user to initiate the process of causing the first or proximal expandable member to evert to enfold and enclose the second or distal expandable member used to secure the obstruction or clot.
- The present invention accordingly provides for an apparatus and method for removal of at least a portion of an obstruction from an obstructed blood vessel for treatment of ischemic stroke. The apparatus includes a telescoping support member, a first or proximal expandable member connected to the telescoping support member, and a second or distal expandable member connected to the first or proximal expandable member. The telescoping support member includes an outer tubular shaft and an inner elongate member that extends through and is slidable within the outer tubular shaft. The first or proximal expandable member has a proximal end that is attached to a distal end of the outer tubular shaft of the telescoping support member, and a distal end of the first or proximal expandable member is attached to a distal portion of the inner elongate member. The first or proximal expandable member preferably has a radially compressed configuration and a radially expanded configuration, as well as a longitudinally extended configuration with proximal and distal ends of the first or proximal expandable member disposed at opposing ends of the first or proximal expandable member, and an everted configuration with the distal end of the first or proximal expandable member withdrawn within the tubular body of the first or proximal expandable member and adjacent to the proximal end of the first or proximal expandable member. The second or distal expandable member preferably has a closed distal end and a closed proximal end, and a tubular mesh body extending between the proximal and distal ends of the second or distal expandable member, and is configured to be deployed into an obstruction within the blood vessel. The closed proximal end of the second or distal expandable member preferably also is permanently joined to the distal end of the inner elongate member of the telescoping support member. The second or distal expandable member also preferably has a radially compressed configuration and a radially expanded configuration, and the tubular mesh body of the second or distal expandable member preferably is configured to radially expand into contact with at least a portion of the obstruction or clot such that a portion of the obstruction or clot is dislodged to enhance blood flow through the blood vessel. In a presently preferred aspect, the tubular mesh body includes a plurality of interstices, at least a portion of which are adapted to allow passage of at least one dislodged portion of the obstruction therethrough in a radial direction into the tubular mesh body.
- In another presently preferred aspect, the tubular body of the first or proximal expandable member includes a plurality strands defining a plurality of interstices therebetween. In another presently preferred aspect, the tubular body of the first or proximal expandable member includes a radiopaque band permanently attached to the distal end of the first or proximal expandable member. In another presently preferred aspect, the tubular mesh body of the second or distal expandable member comprises a plurality of strands, and the plurality of strands may form first and second meshes. In another presently preferred aspect, each of the plurality of strands is oriented in at least one of a helical, longitudinal, and radial direction with respect to the tubular mesh body.
- In another presently preferred aspect, the second or distal expandable member is at least partially constructed of a self-expanding material, and the second or distal expandable member is configured to dislodge the obstruction by fracturing a portion of the obstruction or by extruding a portion of the obstruction.
- In another presently preferred aspect, the second or distal expandable member includes at least one radiopaque portion. In another presently preferred aspect, the second or distal expandable member is at least partially adapted to elute a pharmaceutical agent. In another presently preferred aspect, the pharmaceutical agent is adapted to at least partially lyse the at least one fragment. In another presently preferred aspect, the tubular mesh body of the second or distal expandable member includes a distal portion and a proximal portion, the distal portion of the tubular mesh body being formed of a first mesh, and the proximal portion of the tubular mesh body being made of a second mesh having a plurality of second interstices, at least one of the second interstices being adapted to selectively allow passage of at least one fragment therethrough. In another presently preferred aspect, the first mesh is formed integrally with the second mesh. In another presently preferred aspect, at least one of the first interstices is defined by a plurality of first strands, and at least one of the plurality of first strands is adapted to penetrate into the obstruction to longitudinally separate the at least one fragment from a remaining portion of the obstruction. In another presently preferred aspect, at least one of the second interstices is defined by a plurality of second strands, at least one of the plurality of second strands is adapted to break the at least one fragment into a plurality of subfragments, and at least one of the second interstices is adapted to selectively allow passage therethrough of at least one subfragment to release the at least one subfragment from the second or distal expandable member. In another presently preferred aspect, at least one of the plurality of second interstices is smaller than at least one of the plurality of first interstices. In another presently preferred aspect, a size of at least one of the plurality of second interstices is chosen on the basis of an allowable particulate size of the blood vessel. In another presently preferred aspect, the tubular mesh body of the second or distal expandable member is configured to compress at least a portion of the obstruction against a vessel wall of the blood vessel.
- In the method of the invention, movement of the inner elongate member in a proximal direction relative to the outer tubular shaft of the telescoping support member moves the first or proximal expandable member between the longitudinally extended configuration and the everted configuration such that the first or proximal expandable member covers, enfolds or envelopes the second or distal expandable member.
- Other features and advantages of the present invention will become more apparent from the following detailed description of the preferred embodiments in conjunction with the accompanying drawings, which illustrate, by way of example, the operation of the invention.
-
FIG. 1 is an elevational, schematic diagram of the apparatus of the invention disposed within a patient's vasculature, showing the first and second expandable members in radially expanded configurations within the vasculature, with an obstruction or clot captured within the second or distal expandable member, according to the invention. -
FIG. 2 is an elevational, schematic diagram similar toFIG. 1 , showing the first or proximal expandable member beginning to evert to enfold and cover the second or distal expandable member as the second or distal expandable member is drawn into the first or proximal expandable member. -
FIG. 3 is an elevational, schematic diagram similar toFIG. 2 , showing the first or proximal expandable member everted to enfold and cover the second or distal expandable member, which has been drawn into the first or proximal expandable member. -
FIG. 4 is an enlarged cross-sectional view similar toFIG. 3 . -
FIG. 5 is an elevational, schematic diagram similar toFIG. 3 , showing the first and second expandable members with the captured obstruction or clot being retrieved and withdrawn into a catheter. - Referring to the drawings, which are provided by way of example, and not by way of limitation, the present invention provides for an
apparatus 10 having aproximal end 12 and adistal end 14, for removal of at least a portion of anobstruction 16, such as a clot, for example, from an obstructed blood vessel in a patient'svasculature 18, such as for treatment of ischemic stroke, for example. - The apparatus includes a
telescoping support member 20, including an outertubular shaft 22 having adistal end 24, and an inner elongate member orcore advancement wire 26 having adistal end 28 and aproximal portion 30, and extending through the outer tubular shaft and slidable within the outer tubular shaft. The apparatus also includes a first, proximal expandable member orcover element 32 having aproximal end 34 and adistal end 36, and atubular body 38 extending between the proximal and distal ends of the first or proximal expandable member. The proximal end of the first or proximal expandable member is preferably permanently attached to the distal end of the outer tubular shaft of the telescoping support member, and the distal end of the first or proximal expandable member is preferably permanently attached to adistal portion 40 of the inner elongate member or core advancement wire. The first or proximal expandable member has a radially expanded configuration configured to engage the inner surface of a blood vessel in the patient's vasculature, as shown inFIGS. 1-4 , and a radially compressed configuration, such as when the first or proximal expandable member is disposed within and constrained by an introducer ordelivery catheter 42 having an inner lumen (not shown). The first or proximal expandable member preferably is dimensioned to fit within the inner lumen of the catheter in the radially compressed configuration, and is configured to be constrained from expanding when the first or proximal expandable member is contained within the catheter. - Referring to
FIG. 1 , in the radially expanded configuration, the first or proximal expandable member preferably also has a longitudinally extended configuration with the proximal and distal ends of the first or proximal expandable member disposed at opposing ends of the first or proximal expandable member, and an everted configuration, best shown fully inFIG. 4 , with the distal end of the first or proximal expandable member withdrawn within the tubular body of the first or proximal expandable member adjacent to the proximal end of the first or proximal expandable member. The tubular body of the first or proximal expandable member preferably includes a plurality strands ofmaterial 48 forming a proximal braided portion of the apparatus, defining a plurality ofinterstices 50 therebetween. The first or proximal expandable member also preferably includes at least one radiopaque portion, such as aradiopaque band 52 that is permanently attached to the distal end of the first or proximal expandable member. - The apparatus also includes a second, distal
expandable member 54 at the distal end of the apparatus, that is configured to be deployed into an obstruction or clot within the blood vessel in the patient's vasculature. The second or distal expandable member preferably includes a closed distal end 56 a closedproximal end 58, and atubular mesh body 60 extending between the proximal and distal ends of the second or distal expandable member. The closed proximal end of the second or distal expandable member preferably is permanently joined to the distal end of the inner elongate member of the telescoping support member, such as by soldering, for example, although the second or distal expandable member may alternatively be permanently joined to the distal end of the inner elongate member of the telescoping support member by other similar suitable means, such as by adhesive or by heat shrinkable tubing, or combinations thereof, for example. - The tubular mesh body of the second, distal expandable member preferably is configured to radially expand into contact with at least a portion of the obstruction or clot in the blood vessel, such that a portion of the obstruction is dislodged to enhance blood flow through the blood vessel. The tubular mesh body preferably includes a plurality of
interstices 62, and at least a portion of the interstices preferably are configured to allow passage of at least one dislodged portion of the obstruction therethrough in a radial direction into the tubular mesh body. The tubular mesh body can be formed to include a plurality ofstrands 63 forming first and second meshes, wherein each of the strands may be oriented in at least one of a helical, longitudinal, and radial direction with respect to the tubular mesh body. In a presently preferred aspect, the second or distal expandable member is configured to dislodge the obstruction or clot by fracturing a portion of the obstruction, by extruding a portion of the obstruction, or a combination thereof. In another presently preferred aspect, the second or distal expandable member is at least partially constructed of a superelastic and/or self-expanding material, such as a nickel-titanium alloy which has been memory-shaped into an expanded condition and is compressed into a collapsed condition before use. The second or distal expandable member is constrained in the compressed condition by the introducer or delivery catheter, and preferably self-expands into the expanded condition upon removal from the introducer or delivery catheter. The second or distal expandable member may also include one or more radiopaque portions, such as one or more additional radiopaque bands, for example. In another presently preferred aspect, the second or distal expandable member is at least partially adapted to elute a pharmaceutical agent, such as a pharmaceutical agent designed to at least partially lyse the obstruction or fragment of the obstruction. - The tubular mesh body may include a first mesh in a distal portion of the tubular mesh body having a plurality of first interstices, and a second mesh in a proximal portion of the tubular mesh body being made of having a plurality of second interstices, with at least one of the second interstices being configured to selectively allow passage of at least one fragment therethrough. The first mesh can be formed integrally with the second mesh, for example. At least one of the first interstices may be defined by a plurality of first strands, in which case at least one of the plurality of first strands may be adapted to penetrate into the obstruction to longitudinally separate the at least one fragment from a remaining portion of the obstruction. At least one of the second interstices may be defined by a plurality of second strands, in which case at least one of the plurality of second strands may be adapted to break one or more fragments of the obstruction or clot into a plurality of subfragments, and at least one of the second interstices may be adapted to selectively allow passage of at least one subfragment therethrough to be released from the second or distal expandable member. In another presently preferred aspect, one or more of the plurality of second interstices can be smaller than one or more of the plurality of first interstices, and the size of one or more of the plurality of second interstices may be chosen on the basis of an allowable particulate size of the blood vessel. The tubular mesh body may also be configured to compress at least a portion of the obstruction against a vessel wall of the blood vessel
- Referring to
FIGS. 2 and 3 , in the method of operation of the device of the invention, when the distal element is pulled back, the proximal braided portion starts to evert, initiating covering the distal element, much like pulling a sock over a foot, so that movement of the inner elongate member in a proximal direction relative to the outer tubular shaft of the telescoping support member moves the first or proximal expandable member between the longitudinally extended configuration and the everted configuration, so that the first or proximal expandable member covers, envelopes or enfolds the second or distal expandable member as shown inFIG. 4 , as well as any of the obstruction that may be only partially captured in the second or distal expandable member, such as a portion of the obstruction stuck to or extending from the outside of the second or distal expandable member, for example, so that the second or distal expandable member and captured obstruction material can be withdrawn and retrieved into a catheter, as is illustrated inFIG. 5 . - It will be apparent from the foregoing that while particular forms of the invention have been illustrated and described, various modifications can be made without departing from the spirit and scope of the invention. Accordingly, it is not intended that the invention be limited, except as by the appended claims.
Claims (21)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/801,979 US20140276403A1 (en) | 2013-03-13 | 2013-03-13 | Ischemic stroke device |
IN520DE2014 IN2014DE00520A (en) | 2013-03-13 | 2014-02-25 | |
AU2014201209A AU2014201209A1 (en) | 2013-03-13 | 2014-03-05 | Ischemic stroke device |
KR1020140027549A KR102258237B1 (en) | 2013-03-13 | 2014-03-10 | Ischemic stroke device |
CA2845439A CA2845439C (en) | 2013-03-13 | 2014-03-11 | Ischemic stroke device |
DK14159071.1T DK2786717T3 (en) | 2013-03-13 | 2014-03-12 | Device for ischemic stroke |
JP2014048677A JP6391951B2 (en) | 2013-03-13 | 2014-03-12 | Ischemic stroke device |
EP15203260.3A EP3020344A1 (en) | 2013-03-13 | 2014-03-12 | Ischemic stroke device |
EP14159071.1A EP2786717B1 (en) | 2013-03-13 | 2014-03-12 | Ischemic stroke device |
BRBR102014005957-1A BR102014005957A2 (en) | 2013-03-13 | 2014-03-13 | Ischemic Stroke Device |
CN201410092295.XA CN104042304B (en) | 2013-03-13 | 2014-03-13 | Ishemic stroke device |
US15/983,719 US10687834B2 (en) | 2013-03-13 | 2018-05-18 | Ischemic stroke device |
AU2018220106A AU2018220106A1 (en) | 2013-03-13 | 2018-08-23 | Ischemic stroke device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/801,979 US20140276403A1 (en) | 2013-03-13 | 2013-03-13 | Ischemic stroke device |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US15/983,719 Continuation US10687834B2 (en) | 2013-03-13 | 2018-05-18 | Ischemic stroke device |
Publications (1)
Publication Number | Publication Date |
---|---|
US20140276403A1 true US20140276403A1 (en) | 2014-09-18 |
Family
ID=50342158
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/801,979 Abandoned US20140276403A1 (en) | 2013-03-13 | 2013-03-13 | Ischemic stroke device |
US15/983,719 Active 2033-10-17 US10687834B2 (en) | 2013-03-13 | 2018-05-18 | Ischemic stroke device |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US15/983,719 Active 2033-10-17 US10687834B2 (en) | 2013-03-13 | 2018-05-18 | Ischemic stroke device |
Country Status (10)
Country | Link |
---|---|
US (2) | US20140276403A1 (en) |
EP (2) | EP3020344A1 (en) |
JP (1) | JP6391951B2 (en) |
KR (1) | KR102258237B1 (en) |
CN (1) | CN104042304B (en) |
AU (2) | AU2014201209A1 (en) |
BR (1) | BR102014005957A2 (en) |
CA (1) | CA2845439C (en) |
DK (1) | DK2786717T3 (en) |
IN (1) | IN2014DE00520A (en) |
Cited By (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20150080896A1 (en) | 2013-07-19 | 2015-03-19 | Ouroboros Medical, Inc. | Anti-clogging device for a vacuum-assisted, tissue removal system |
US20160296315A1 (en) * | 2013-11-28 | 2016-10-13 | Innoventions Ltd. | Filtration and entrapment apparatus and method of use |
US9579116B1 (en) | 2015-08-06 | 2017-02-28 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9592068B2 (en) | 2013-03-15 | 2017-03-14 | Insera Therapeutics, Inc. | Free end vascular treatment systems |
US9744024B2 (en) | 2015-08-06 | 2017-08-29 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9750524B2 (en) | 2013-03-15 | 2017-09-05 | Insera Therapeutics, Inc. | Shape-set textile structure based mechanical thrombectomy systems |
US9770251B2 (en) | 2012-08-13 | 2017-09-26 | Microvention, Inc. | Shaped removal device |
US9833251B2 (en) | 2013-03-15 | 2017-12-05 | Insera Therapeutics, Inc. | Variably bulbous vascular treatment devices |
US9833252B2 (en) | 2013-03-15 | 2017-12-05 | Microvention, Inc. | Multi-component obstruction removal system and method |
US9901435B2 (en) | 2013-03-15 | 2018-02-27 | Insera Therapeutics, Inc. | Longitudinally variable vascular treatment devices |
US20180070968A1 (en) * | 2016-09-12 | 2018-03-15 | Stryker Corporation | Self-rolling thrombectomy apparatuses and methods |
US9999493B2 (en) | 2015-08-06 | 2018-06-19 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US20180325535A1 (en) * | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
US20180325531A1 (en) * | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
WO2018209310A1 (en) | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
WO2018237185A1 (en) * | 2017-06-22 | 2018-12-27 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
US20190046219A1 (en) * | 2017-01-10 | 2019-02-14 | Inari Medical, Inc. | Devices and methods for treating vascular occlusion |
US10299824B2 (en) * | 2016-09-07 | 2019-05-28 | Daniel Ezra Walzman | Rotating separator, irrigator microcatheter for thrombectomy |
US10307242B2 (en) * | 2016-09-07 | 2019-06-04 | Daniel Ezra Walzman | Simultaneous rotating separator, irrigator microcatheter for thrombectomy and method of use |
US10390926B2 (en) | 2013-07-29 | 2019-08-27 | Insera Therapeutics, Inc. | Aspiration devices and methods |
US10448967B2 (en) | 2011-12-03 | 2019-10-22 | DePuy Synthes Products, Inc. | Discectomy kits with an obturator, guard cannula |
US10478322B2 (en) * | 2017-06-19 | 2019-11-19 | Covidien Lp | Retractor device for transforming a retrieval device from a deployed position to a delivery position |
US10512478B2 (en) | 2016-04-25 | 2019-12-24 | Stryker Corporation | Clot-engulfing mechanical thrombectomy apparatuses |
US10517624B2 (en) | 2016-06-03 | 2019-12-31 | Stryker Corporation | Inverting thrombectomy apparatuses and methods |
US10709464B2 (en) | 2017-05-12 | 2020-07-14 | Covidien Lp | Retrieval of material from vessel lumens |
WO2020146343A1 (en) * | 2019-01-08 | 2020-07-16 | Progressive NEURO, Inc. | Apparatus, system, and method for vasculature obstruction removal |
US10779843B2 (en) | 2017-11-09 | 2020-09-22 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10835269B1 (en) | 2018-09-10 | 2020-11-17 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US10842513B2 (en) | 2016-04-25 | 2020-11-24 | Stryker Corporation | Methods for advancing inverting mechanical thrombectomy apparatuses in the vasculature |
US10888343B2 (en) | 2016-04-25 | 2021-01-12 | Stryker Corporation | Anti-jamming and macerating thrombectomy apparatuses and methods |
US11000682B2 (en) | 2017-09-06 | 2021-05-11 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11026709B2 (en) | 2015-09-28 | 2021-06-08 | Stryker Corporation | Mechanical thrombectomy apparatuses and methods |
US11058451B2 (en) | 2015-10-23 | 2021-07-13 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US11058445B2 (en) | 2013-10-21 | 2021-07-13 | Inari Medical, Inc. | Methods and apparatus for treating embolism |
US11103265B2 (en) | 2018-05-14 | 2021-08-31 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US11129630B2 (en) | 2017-05-12 | 2021-09-28 | Covidien Lp | Retrieval of material from vessel lumens |
US11141178B2 (en) * | 2017-03-03 | 2021-10-12 | Maria G. Aboytes | Systems, devices, and methods for obstruction retrieval and treatment |
US11147571B2 (en) | 2012-09-24 | 2021-10-19 | Inari Medical, Inc. | Device and method for treating vascular occlusion |
US11191555B2 (en) | 2017-05-12 | 2021-12-07 | Covidien Lp | Retrieval of material from vessel lumens |
US11253291B2 (en) | 2018-09-10 | 2022-02-22 | Stryker Corporation | Laser slotted grabbing device |
US11259820B2 (en) | 2016-09-07 | 2022-03-01 | Daniel Ezra Walzman | Methods and devices to ameliorate vascular obstruction |
US11433218B2 (en) | 2015-12-18 | 2022-09-06 | Inari Medical, Inc. | Catheter shaft and associated devices, systems, and methods |
US11439492B2 (en) | 2016-09-07 | 2022-09-13 | Daniel Ezra Walzman | Lasso filter tipped microcatheter for simultaneous rotating separator, irrigator for thrombectomy and method for use |
US11497512B2 (en) | 2016-04-25 | 2022-11-15 | Stryker Corporation | Inverting thrombectomy apparatuses and methods |
US11529158B2 (en) | 2004-03-25 | 2022-12-20 | Inari Medical, Inc. | Method for treating vascular occlusion |
US11554005B2 (en) | 2018-08-13 | 2023-01-17 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11596427B2 (en) | 2017-06-12 | 2023-03-07 | Covidien Lp | Tools for sheathing treatment devices and associated systems and methods |
CN115844489A (en) * | 2022-12-06 | 2023-03-28 | 杭州亿科医疗科技有限公司 | Supplementary thrombus entrapment device that gets back of thrombus device |
US11622781B2 (en) | 2020-01-30 | 2023-04-11 | Julier Medical AG | Apparatus and method for neurovascular endoluminal intervention |
US11648028B2 (en) | 2012-11-20 | 2023-05-16 | Inari Medical, Inc. | Methods and apparatus for treating embolism |
US11737767B2 (en) | 2022-01-21 | 2023-08-29 | Julier Medical AG | Neurovascular catheter and method of use |
US11793531B2 (en) | 2019-11-05 | 2023-10-24 | Vascular Medcure, Inc. | Axial lengthening thrombus capture system, tensioning system and expandable funnel catheter |
US11849963B2 (en) | 2018-01-26 | 2023-12-26 | Inari Medical, Inc. | Single insertion delivery system for treating embolism and associated systems and methods |
US11864779B2 (en) | 2019-10-16 | 2024-01-09 | Inari Medical, Inc. | Systems, devices, and methods for treating vascular occlusions |
US11877752B2 (en) | 2016-09-07 | 2024-01-23 | Daniel Ezra Walzman | Filterless aspiration, irrigating, macerating, rotating microcatheter and method of use |
US11896247B2 (en) | 2016-04-25 | 2024-02-13 | Stryker Corporation | Inverting mechanical thrombectomy apparatuses |
US11918244B2 (en) | 2015-10-23 | 2024-03-05 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9402707B2 (en) | 2008-07-22 | 2016-08-02 | Neuravi Limited | Clot capture systems and associated methods |
EP2629684B1 (en) | 2010-10-22 | 2018-07-25 | Neuravi Limited | Clot engagement and removal system |
US11259824B2 (en) | 2011-03-09 | 2022-03-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
WO2014139845A1 (en) | 2013-03-14 | 2014-09-18 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
US9433429B2 (en) | 2013-03-14 | 2016-09-06 | Neuravi Limited | Clot retrieval devices |
ES2713633T3 (en) | 2013-03-14 | 2019-05-23 | Neuravi Ltd | Devices and methods for elimination of severe blockages of blood vessels |
US10617435B2 (en) | 2014-11-26 | 2020-04-14 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
US11253278B2 (en) | 2014-11-26 | 2022-02-22 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
US10363054B2 (en) | 2014-11-26 | 2019-07-30 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
CN105476689A (en) * | 2015-12-28 | 2016-04-13 | 威海维心医疗设备有限公司 | Thrombus extraction support device |
JP7046924B2 (en) * | 2016-09-06 | 2022-04-04 | ニューラヴィ・リミテッド | Clot recovery device for removing obstructive clots from blood vessels |
US10265085B2 (en) * | 2016-11-16 | 2019-04-23 | Osama O. Zaidat | System and device for engulfing thrombi |
CN106618676B (en) * | 2016-12-30 | 2020-07-28 | 上海加奇生物科技苏州有限公司 | Intravascular thrombus taking-out device |
WO2020033853A1 (en) * | 2018-08-10 | 2020-02-13 | Gifford Hanson S Iii | Mechanical venous clot retrieval |
US11406416B2 (en) | 2018-10-02 | 2022-08-09 | Neuravi Limited | Joint assembly for vasculature obstruction capture device |
US11712231B2 (en) | 2019-10-29 | 2023-08-01 | Neuravi Limited | Proximal locking assembly design for dual stent mechanical thrombectomy device |
US11517340B2 (en) | 2019-12-03 | 2022-12-06 | Neuravi Limited | Stentriever devices for removing an occlusive clot from a vessel and methods thereof |
US11717308B2 (en) | 2020-04-17 | 2023-08-08 | Neuravi Limited | Clot retrieval device for removing heterogeneous clots from a blood vessel |
US11871946B2 (en) | 2020-04-17 | 2024-01-16 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
US11730501B2 (en) | 2020-04-17 | 2023-08-22 | Neuravi Limited | Floating clot retrieval device for removing clots from a blood vessel |
US11737771B2 (en) | 2020-06-18 | 2023-08-29 | Neuravi Limited | Dual channel thrombectomy device |
US11937836B2 (en) | 2020-06-22 | 2024-03-26 | Neuravi Limited | Clot retrieval system with expandable clot engaging framework |
US11395669B2 (en) | 2020-06-23 | 2022-07-26 | Neuravi Limited | Clot retrieval device with flexible collapsible frame |
US11439418B2 (en) | 2020-06-23 | 2022-09-13 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
US11864781B2 (en) | 2020-09-23 | 2024-01-09 | Neuravi Limited | Rotating frame thrombectomy device |
US11937837B2 (en) | 2020-12-29 | 2024-03-26 | Neuravi Limited | Fibrin rich / soft clot mechanical thrombectomy device |
CN114903538A (en) * | 2021-02-09 | 2022-08-16 | 北京术锐技术有限公司 | Growable instrument and surgical robot system |
Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4425908A (en) * | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
US4643184A (en) * | 1982-09-29 | 1987-02-17 | Mobin Uddin Kazi | Embolus trap |
US5108419A (en) * | 1990-08-16 | 1992-04-28 | Evi Corporation | Endovascular filter and method for use thereof |
US5855565A (en) * | 1997-02-21 | 1999-01-05 | Bar-Cohen; Yaniv | Cardiovascular mechanically expanding catheter |
US20020138095A1 (en) * | 1994-07-08 | 2002-09-26 | Microvena Corporation | Method of forming medical devices; intravascular occlusion devices |
US20060259067A1 (en) * | 2005-05-10 | 2006-11-16 | Welch Eric D | Intravascular filter with drug reservoir |
US20070208370A1 (en) * | 2004-03-25 | 2007-09-06 | Hauser David L | Vascular Filter Device |
US7875050B2 (en) * | 1997-09-30 | 2011-01-25 | Target Therapeutics, Inc. | Mechanical clot treatment device |
US8052640B2 (en) * | 2006-02-01 | 2011-11-08 | The Cleveland Clinic Foundation | Method and apparatus for increasing blood flow through an obstructed blood vessel |
US20110288572A1 (en) * | 2010-01-22 | 2011-11-24 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
US20120197285A1 (en) * | 2009-03-06 | 2012-08-02 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US755663A (en) | 1903-07-30 | 1904-03-29 | John E Hill | Fish-mouth opener. |
US4611594A (en) * | 1984-04-11 | 1986-09-16 | Northwestern University | Medical instrument for containment and removal of calculi |
EP0200668A3 (en) * | 1985-04-25 | 1988-03-09 | FOGARTY, Thomas J. | Apparatus and method for dislodging and removing occlusive objects from body passages |
US4927426A (en) * | 1989-01-03 | 1990-05-22 | Dretler Stephen P | Catheter device |
DE9109006U1 (en) * | 1991-07-22 | 1991-10-10 | Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med., 5100 Aachen, De | |
US5846251A (en) | 1996-07-22 | 1998-12-08 | Hart; Charles C. | Access device with expandable containment member |
US5972019A (en) * | 1996-07-25 | 1999-10-26 | Target Therapeutics, Inc. | Mechanical clot treatment device |
US6210370B1 (en) | 1997-01-10 | 2001-04-03 | Applied Medical Resources Corporation | Access device with expandable containment member |
WO1999039649A1 (en) | 1998-02-10 | 1999-08-12 | Dubrul William R | Occlusion, anchoring, tensioning and flow direction apparatus and methods for use |
US7220271B2 (en) | 2003-01-30 | 2007-05-22 | Ev3 Inc. | Embolic filters having multiple layers and controlled pore size |
EP1617893B1 (en) | 2003-04-16 | 2018-06-06 | Genesis Technologies LLC. | Medical device and method |
US7604650B2 (en) | 2003-10-06 | 2009-10-20 | 3F Therapeutics, Inc. | Method and assembly for distal embolic protection |
US8252017B2 (en) | 2005-10-18 | 2012-08-28 | Cook Medical Technologies Llc | Invertible filter for embolic protection |
US20080071307A1 (en) | 2006-09-19 | 2008-03-20 | Cook Incorporated | Apparatus and methods for in situ embolic protection |
DE102006044831A1 (en) * | 2006-09-20 | 2008-04-03 | Phenox Gmbh | Device for removing thrombi from blood vessels |
US8535334B2 (en) | 2007-04-17 | 2013-09-17 | Lazarus Effect, Inc. | Complex wire formed devices |
US8066757B2 (en) | 2007-10-17 | 2011-11-29 | Mindframe, Inc. | Blood flow restoration and thrombus management methods |
WO2009055782A1 (en) * | 2007-10-26 | 2009-04-30 | Possis Medical, Inc. | Intravascular guidewire filter system for pulmonary embolism protection and embolism removal or maceration |
EP2231037B1 (en) * | 2007-12-26 | 2015-08-12 | Lazarus Effect, Inc. | Retrieval systems |
US20110152920A1 (en) | 2008-12-02 | 2011-06-23 | Rapid Medical Ltd. | Embolectomy device |
US8388644B2 (en) | 2008-12-29 | 2013-03-05 | Cook Medical Technologies Llc | Embolic protection device and method of use |
ES2683178T3 (en) * | 2011-05-23 | 2018-09-25 | Covidien Lp | Extraction systems |
-
2013
- 2013-03-13 US US13/801,979 patent/US20140276403A1/en not_active Abandoned
-
2014
- 2014-02-25 IN IN520DE2014 patent/IN2014DE00520A/en unknown
- 2014-03-05 AU AU2014201209A patent/AU2014201209A1/en not_active Abandoned
- 2014-03-10 KR KR1020140027549A patent/KR102258237B1/en active IP Right Grant
- 2014-03-11 CA CA2845439A patent/CA2845439C/en not_active Expired - Fee Related
- 2014-03-12 JP JP2014048677A patent/JP6391951B2/en active Active
- 2014-03-12 EP EP15203260.3A patent/EP3020344A1/en not_active Withdrawn
- 2014-03-12 EP EP14159071.1A patent/EP2786717B1/en active Active
- 2014-03-12 DK DK14159071.1T patent/DK2786717T3/en active
- 2014-03-13 CN CN201410092295.XA patent/CN104042304B/en active Active
- 2014-03-13 BR BRBR102014005957-1A patent/BR102014005957A2/en active Search and Examination
-
2018
- 2018-05-18 US US15/983,719 patent/US10687834B2/en active Active
- 2018-08-23 AU AU2018220106A patent/AU2018220106A1/en not_active Abandoned
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4425908A (en) * | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
US4643184A (en) * | 1982-09-29 | 1987-02-17 | Mobin Uddin Kazi | Embolus trap |
US5108419A (en) * | 1990-08-16 | 1992-04-28 | Evi Corporation | Endovascular filter and method for use thereof |
US20020138095A1 (en) * | 1994-07-08 | 2002-09-26 | Microvena Corporation | Method of forming medical devices; intravascular occlusion devices |
US5855565A (en) * | 1997-02-21 | 1999-01-05 | Bar-Cohen; Yaniv | Cardiovascular mechanically expanding catheter |
US7875050B2 (en) * | 1997-09-30 | 2011-01-25 | Target Therapeutics, Inc. | Mechanical clot treatment device |
US20070208370A1 (en) * | 2004-03-25 | 2007-09-06 | Hauser David L | Vascular Filter Device |
US20060259067A1 (en) * | 2005-05-10 | 2006-11-16 | Welch Eric D | Intravascular filter with drug reservoir |
US8052640B2 (en) * | 2006-02-01 | 2011-11-08 | The Cleveland Clinic Foundation | Method and apparatus for increasing blood flow through an obstructed blood vessel |
US20120197285A1 (en) * | 2009-03-06 | 2012-08-02 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
US20110288572A1 (en) * | 2010-01-22 | 2011-11-24 | Lazarus Effect, Inc. | Retrieval systems and methods for use thereof |
Cited By (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11832838B2 (en) | 2004-03-25 | 2023-12-05 | Inari Medical, Inc. | Method for treating vascular occlusion |
US11529158B2 (en) | 2004-03-25 | 2022-12-20 | Inari Medical, Inc. | Method for treating vascular occlusion |
US11925369B2 (en) | 2004-03-25 | 2024-03-12 | Inari Medical, Inc. | Method for treating vascular occlusion |
US11839393B2 (en) | 2004-03-25 | 2023-12-12 | Inari Medical, Inc. | Method for treating vascular occlusion |
US11832837B2 (en) | 2004-03-25 | 2023-12-05 | Inari Medical, Inc. | Method for treating vascular occlusion |
US10448967B2 (en) | 2011-12-03 | 2019-10-22 | DePuy Synthes Products, Inc. | Discectomy kits with an obturator, guard cannula |
US9770251B2 (en) | 2012-08-13 | 2017-09-26 | Microvention, Inc. | Shaped removal device |
US11147571B2 (en) | 2012-09-24 | 2021-10-19 | Inari Medical, Inc. | Device and method for treating vascular occlusion |
US11648028B2 (en) | 2012-11-20 | 2023-05-16 | Inari Medical, Inc. | Methods and apparatus for treating embolism |
US9833252B2 (en) | 2013-03-15 | 2017-12-05 | Microvention, Inc. | Multi-component obstruction removal system and method |
US10463468B2 (en) | 2013-03-15 | 2019-11-05 | Insera Therapeutics, Inc. | Thrombus aspiration with different intensity levels |
US9901435B2 (en) | 2013-03-15 | 2018-02-27 | Insera Therapeutics, Inc. | Longitudinally variable vascular treatment devices |
US9833251B2 (en) | 2013-03-15 | 2017-12-05 | Insera Therapeutics, Inc. | Variably bulbous vascular treatment devices |
US9750524B2 (en) | 2013-03-15 | 2017-09-05 | Insera Therapeutics, Inc. | Shape-set textile structure based mechanical thrombectomy systems |
US9592068B2 (en) | 2013-03-15 | 2017-03-14 | Insera Therapeutics, Inc. | Free end vascular treatment systems |
US10342655B2 (en) | 2013-03-15 | 2019-07-09 | Insera Therapeutics, Inc. | Methods of treating a thrombus in an artery using cyclical aspiration patterns |
US10335260B2 (en) | 2013-03-15 | 2019-07-02 | Insera Therapeutics, Inc. | Methods of treating a thrombus in a vein using cyclical aspiration patterns |
US11298144B2 (en) | 2013-03-15 | 2022-04-12 | Insera Therapeutics, Inc. | Thrombus aspiration facilitation systems |
US10251739B2 (en) | 2013-03-15 | 2019-04-09 | Insera Therapeutics, Inc. | Thrombus aspiration using an operator-selectable suction pattern |
US20150080896A1 (en) | 2013-07-19 | 2015-03-19 | Ouroboros Medical, Inc. | Anti-clogging device for a vacuum-assisted, tissue removal system |
US10342563B2 (en) | 2013-07-19 | 2019-07-09 | DePuy Synthes Products, Inc. | Anti-clogging device for a vacuum-assisted, tissue removal system |
US10390926B2 (en) | 2013-07-29 | 2019-08-27 | Insera Therapeutics, Inc. | Aspiration devices and methods |
US10751159B2 (en) | 2013-07-29 | 2020-08-25 | Insera Therapeutics, Inc. | Systems for aspirating thrombus during neurosurgical procedures |
US11058445B2 (en) | 2013-10-21 | 2021-07-13 | Inari Medical, Inc. | Methods and apparatus for treating embolism |
US11937838B2 (en) | 2013-10-21 | 2024-03-26 | Inari Medical, Inc. | Methods and apparatus for treating embolism |
US10327883B2 (en) * | 2013-11-28 | 2019-06-25 | Innovations Ltd. | Filtration and entrapment apparatus and method of use |
US20160296315A1 (en) * | 2013-11-28 | 2016-10-13 | Innoventions Ltd. | Filtration and entrapment apparatus and method of use |
US11490913B2 (en) | 2015-08-06 | 2022-11-08 | Vascular Medcure, Inc. | Axial lengthening thrombus capture system |
US10238482B2 (en) | 2015-08-06 | 2019-03-26 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US10143482B2 (en) | 2015-08-06 | 2018-12-04 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US11471175B2 (en) | 2015-08-06 | 2022-10-18 | Vascular Medcure, Inc. | Axial lengthening thrombus capture system |
US11510691B2 (en) | 2015-08-06 | 2022-11-29 | Vascular Medcure, Inc. | Axial lengthening thrombus capture system |
US10376275B2 (en) | 2015-08-06 | 2019-08-13 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US10070879B2 (en) | 2015-08-06 | 2018-09-11 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9999493B2 (en) | 2015-08-06 | 2018-06-19 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9579116B1 (en) | 2015-08-06 | 2017-02-28 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US10456236B2 (en) | 2015-08-06 | 2019-10-29 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9844386B2 (en) | 2015-08-06 | 2017-12-19 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9636206B2 (en) | 2015-08-06 | 2017-05-02 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US10512479B2 (en) | 2015-08-06 | 2019-12-24 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US9744024B2 (en) | 2015-08-06 | 2017-08-29 | Kp Medcure, Inc. | Axial lengthening thrombus capture system |
US11026709B2 (en) | 2015-09-28 | 2021-06-08 | Stryker Corporation | Mechanical thrombectomy apparatuses and methods |
US11471176B2 (en) | 2015-09-28 | 2022-10-18 | Stryker Corporation | Biopsy methods |
US11918243B2 (en) | 2015-10-23 | 2024-03-05 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US11058451B2 (en) | 2015-10-23 | 2021-07-13 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US11918244B2 (en) | 2015-10-23 | 2024-03-05 | Inari Medical, Inc. | Intravascular treatment of vascular occlusion and associated devices, systems, and methods |
US11433218B2 (en) | 2015-12-18 | 2022-09-06 | Inari Medical, Inc. | Catheter shaft and associated devices, systems, and methods |
US10888342B2 (en) | 2016-04-25 | 2021-01-12 | Stryker Corporation | Anti-jamming and macerating thrombectomy apparatuses and methods |
US10888343B2 (en) | 2016-04-25 | 2021-01-12 | Stryker Corporation | Anti-jamming and macerating thrombectomy apparatuses and methods |
US10561431B2 (en) * | 2016-04-25 | 2020-02-18 | Stryker Corporation | Pre-loaded inverting tractor thrombectomy apparatuses and methods |
US10512478B2 (en) | 2016-04-25 | 2019-12-24 | Stryker Corporation | Clot-engulfing mechanical thrombectomy apparatuses |
US11497514B2 (en) | 2016-04-25 | 2022-11-15 | Stryker Corporation | Pre-loaded inverting tractor thrombectomy apparatuses and methods |
US11497512B2 (en) | 2016-04-25 | 2022-11-15 | Stryker Corporation | Inverting thrombectomy apparatuses and methods |
US10842513B2 (en) | 2016-04-25 | 2020-11-24 | Stryker Corporation | Methods for advancing inverting mechanical thrombectomy apparatuses in the vasculature |
US11896247B2 (en) | 2016-04-25 | 2024-02-13 | Stryker Corporation | Inverting mechanical thrombectomy apparatuses |
US20200107842A1 (en) * | 2016-04-25 | 2020-04-09 | Stryker Corporation | Clot-engulfing mechanical thrombectomy apparatuses |
US10517624B2 (en) | 2016-06-03 | 2019-12-31 | Stryker Corporation | Inverting thrombectomy apparatuses and methods |
US11559320B2 (en) | 2016-06-03 | 2023-01-24 | Stryker Corporation | Inverting thrombectomy apparatuses and methods |
US11642211B2 (en) | 2016-09-07 | 2023-05-09 | Daniel Ezra Walzman | Lasso filter tipped microcatheter for simultaneous rotating separator, irrigator for thrombectomy and method for use |
US11672643B2 (en) | 2016-09-07 | 2023-06-13 | Daniel Ezra Walzman | Endovascular device with expandable filter |
US11439492B2 (en) | 2016-09-07 | 2022-09-13 | Daniel Ezra Walzman | Lasso filter tipped microcatheter for simultaneous rotating separator, irrigator for thrombectomy and method for use |
US11642210B2 (en) | 2016-09-07 | 2023-05-09 | Daniel Ezra Walzman | Lasso filter tipped microcatheter for simultaneous rotating separator, irrigator for thrombectomy and method for use |
US10299824B2 (en) * | 2016-09-07 | 2019-05-28 | Daniel Ezra Walzman | Rotating separator, irrigator microcatheter for thrombectomy |
US11259820B2 (en) | 2016-09-07 | 2022-03-01 | Daniel Ezra Walzman | Methods and devices to ameliorate vascular obstruction |
US10307242B2 (en) * | 2016-09-07 | 2019-06-04 | Daniel Ezra Walzman | Simultaneous rotating separator, irrigator microcatheter for thrombectomy and method of use |
US10314684B2 (en) * | 2016-09-07 | 2019-06-11 | Daniel Ezra Walzman | Simultaneous rotating separator, irrigator microcatheter for thrombectomy |
US11877752B2 (en) | 2016-09-07 | 2024-01-23 | Daniel Ezra Walzman | Filterless aspiration, irrigating, macerating, rotating microcatheter and method of use |
US11627973B2 (en) | 2016-09-12 | 2023-04-18 | Stryker Corporation | Self-rolling apparatuses and methods for removing material from a body lumen |
US20180070968A1 (en) * | 2016-09-12 | 2018-03-15 | Stryker Corporation | Self-rolling thrombectomy apparatuses and methods |
US10610245B2 (en) * | 2016-09-12 | 2020-04-07 | Stryker Corporation | Self-rolling thrombectomy apparatuses and methods |
CN109922744A (en) * | 2016-09-12 | 2019-06-21 | 斯瑞克公司 | From turnup thrombectomy device and method |
CN110312481A (en) * | 2016-10-24 | 2019-10-08 | 伊纳里医疗有限公司 | Device and method for treating vascular occlusion |
US20190046219A1 (en) * | 2017-01-10 | 2019-02-14 | Inari Medical, Inc. | Devices and methods for treating vascular occlusion |
US11806033B2 (en) | 2017-01-10 | 2023-11-07 | Inari Medical, Inc. | Devices and methods for treating vascular occlusion |
US10912577B2 (en) * | 2017-01-10 | 2021-02-09 | Inari Medical, Inc. | Devices and methods for treating vascular occlusion |
US11141178B2 (en) * | 2017-03-03 | 2021-10-12 | Maria G. Aboytes | Systems, devices, and methods for obstruction retrieval and treatment |
US20180325531A1 (en) * | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
US11298145B2 (en) * | 2017-05-12 | 2022-04-12 | Covidien Lp | Retrieval of material from vessel lumens |
EP3621533A4 (en) * | 2017-05-12 | 2020-12-16 | Covidien LP | Retrieval of material from vessel lumens |
WO2018209310A1 (en) | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
US20180325535A1 (en) * | 2017-05-12 | 2018-11-15 | Covidien Lp | Retrieval of material from vessel lumens |
US11684379B2 (en) | 2017-05-12 | 2023-06-27 | Covidien Lp | Retrieval of material from vessel lumens |
US11129630B2 (en) | 2017-05-12 | 2021-09-28 | Covidien Lp | Retrieval of material from vessel lumens |
US10722257B2 (en) * | 2017-05-12 | 2020-07-28 | Covidien Lp | Retrieval of material from vessel lumens |
US11191555B2 (en) | 2017-05-12 | 2021-12-07 | Covidien Lp | Retrieval of material from vessel lumens |
US10709464B2 (en) | 2017-05-12 | 2020-07-14 | Covidien Lp | Retrieval of material from vessel lumens |
US11596427B2 (en) | 2017-06-12 | 2023-03-07 | Covidien Lp | Tools for sheathing treatment devices and associated systems and methods |
US11304834B2 (en) * | 2017-06-19 | 2022-04-19 | Covidien Lp | Retractor device for transforming a retrieval device from a deployed position to a delivery position |
US10478322B2 (en) * | 2017-06-19 | 2019-11-19 | Covidien Lp | Retractor device for transforming a retrieval device from a deployed position to a delivery position |
US10575864B2 (en) * | 2017-06-22 | 2020-03-03 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
US20180368863A1 (en) * | 2017-06-22 | 2018-12-27 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
EP3641675A4 (en) * | 2017-06-22 | 2021-03-10 | Covidien LP | Securing element for resheathing an intravascular device and associated systems and methods |
WO2018237185A1 (en) * | 2017-06-22 | 2018-12-27 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
US11497513B2 (en) | 2017-06-22 | 2022-11-15 | Covidien Lp | Securing element for resheathing an intravascular device and associated systems and methods |
CN111225623A (en) * | 2017-06-22 | 2020-06-02 | 柯惠有限合伙公司 | Fastening elements for resheathing intravascular devices and associated systems and methods |
US11000682B2 (en) | 2017-09-06 | 2021-05-11 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11865291B2 (en) | 2017-09-06 | 2024-01-09 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11697012B2 (en) | 2017-09-06 | 2023-07-11 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11697011B2 (en) | 2017-09-06 | 2023-07-11 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11844921B2 (en) | 2017-09-06 | 2023-12-19 | Inari Medical, Inc. | Hemostasis valves and methods of use |
US11812980B2 (en) | 2017-11-09 | 2023-11-14 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10779843B2 (en) | 2017-11-09 | 2020-09-22 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10835268B2 (en) | 2017-11-09 | 2020-11-17 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10912576B2 (en) | 2017-11-09 | 2021-02-09 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10863999B2 (en) | 2017-11-09 | 2020-12-15 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US10856894B2 (en) | 2017-11-09 | 2020-12-08 | Stryker Corporation | Inverting thrombectomy apparatuses having enhanced tracking |
US11849963B2 (en) | 2018-01-26 | 2023-12-26 | Inari Medical, Inc. | Single insertion delivery system for treating embolism and associated systems and methods |
US11896251B2 (en) | 2018-05-14 | 2024-02-13 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US11103265B2 (en) | 2018-05-14 | 2021-08-31 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US11559382B2 (en) | 2018-08-13 | 2023-01-24 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11642209B2 (en) | 2018-08-13 | 2023-05-09 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11833023B2 (en) | 2018-08-13 | 2023-12-05 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11554005B2 (en) | 2018-08-13 | 2023-01-17 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11890180B2 (en) | 2018-08-13 | 2024-02-06 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11744691B2 (en) | 2018-08-13 | 2023-09-05 | Inari Medical, Inc. | System for treating embolism and associated devices and methods |
US11771450B2 (en) | 2018-09-10 | 2023-10-03 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US10835269B1 (en) | 2018-09-10 | 2020-11-17 | Stryker Corporation | Inverting thrombectomy apparatuses and methods of use |
US11253291B2 (en) | 2018-09-10 | 2022-02-22 | Stryker Corporation | Laser slotted grabbing device |
WO2020146343A1 (en) * | 2019-01-08 | 2020-07-16 | Progressive NEURO, Inc. | Apparatus, system, and method for vasculature obstruction removal |
US11864779B2 (en) | 2019-10-16 | 2024-01-09 | Inari Medical, Inc. | Systems, devices, and methods for treating vascular occlusions |
US11937834B2 (en) | 2019-10-16 | 2024-03-26 | Inari Medical, Inc. | Systems, devices, and methods for treating vascular occlusions |
US11793531B2 (en) | 2019-11-05 | 2023-10-24 | Vascular Medcure, Inc. | Axial lengthening thrombus capture system, tensioning system and expandable funnel catheter |
US11766272B2 (en) | 2020-01-30 | 2023-09-26 | Julier Medical AG | Apparatus and methods for neurovascular endoluminal intervention |
US11911057B2 (en) | 2020-01-30 | 2024-02-27 | Julier Medical AG | Catheter apparatus and methods for endoluminal intervention |
US11622781B2 (en) | 2020-01-30 | 2023-04-11 | Julier Medical AG | Apparatus and method for neurovascular endoluminal intervention |
US11737767B2 (en) | 2022-01-21 | 2023-08-29 | Julier Medical AG | Neurovascular catheter and method of use |
CN115844489A (en) * | 2022-12-06 | 2023-03-28 | 杭州亿科医疗科技有限公司 | Supplementary thrombus entrapment device that gets back of thrombus device |
Also Published As
Publication number | Publication date |
---|---|
IN2014DE00520A (en) | 2015-06-12 |
CN104042304A (en) | 2014-09-17 |
DK2786717T3 (en) | 2016-04-11 |
CN104042304B (en) | 2018-10-26 |
EP2786717A2 (en) | 2014-10-08 |
CA2845439C (en) | 2021-04-06 |
JP2014176660A (en) | 2014-09-25 |
US10687834B2 (en) | 2020-06-23 |
EP3020344A1 (en) | 2016-05-18 |
EP2786717A3 (en) | 2014-11-19 |
AU2014201209A1 (en) | 2014-10-02 |
EP2786717B1 (en) | 2016-01-13 |
US20190133628A1 (en) | 2019-05-09 |
AU2018220106A1 (en) | 2018-09-13 |
KR20140112415A (en) | 2014-09-23 |
CA2845439A1 (en) | 2014-09-13 |
BR102014005957A2 (en) | 2015-06-23 |
KR102258237B1 (en) | 2021-06-01 |
JP6391951B2 (en) | 2018-09-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10687834B2 (en) | Ischemic stroke device | |
US10729459B2 (en) | Flow restoration systems and methods for use | |
US11648021B2 (en) | Retrieval apparatus and methods for use | |
EP3057516B1 (en) | Mechanical thrombectomy device with proximal occlusion | |
EP2544603B1 (en) | Obstruction removal assembly | |
CN107126244B (en) | Extraction system and method of use | |
EP3827765A1 (en) | An aspiration catheter, systems, and methods thereof | |
CN112890914A (en) | Stent embolectomy device and method for removing occluded clot from a blood vessel | |
CN110494099B (en) | Device and method for clot and plaque contraction | |
US11737769B2 (en) | Clot retrievers and methods for deployment | |
US20220378566A1 (en) | Intravascular catheter having an expandable incising portion and embolic protection device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: DEPUY SYNTHES PRODUCTS, LLC, MASSACHUSETTS Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:FOLLMER, BRETT ALLEN;VALLESTEROS ASUNCION, SHEILA;REEL/FRAME:030655/0345 Effective date: 20130422 |
|
AS | Assignment |
Owner name: DEPUY SYNTHES PRODUCTS, INC., MASSACHUSETTS Free format text: CHANGE OF NAME;ASSIGNOR:DEPUY SYNTHES PRODUCTS, LLC;REEL/FRAME:035074/0647 Effective date: 20141219 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- AFTER EXAMINER'S ANSWER OR BOARD OF APPEALS DECISION |