US2409734A - Instrument for blood transfusion - Google Patents

Instrument for blood transfusion Download PDF

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US2409734A
US2409734A US457340A US45734042A US2409734A US 2409734 A US2409734 A US 2409734A US 457340 A US457340 A US 457340A US 45734042 A US45734042 A US 45734042A US 2409734 A US2409734 A US 2409734A
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bag
instrument
blood
liquid
bushing
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US457340A
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Bucher Rudolf
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Swiss Firm Of G Laubscher & Co
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Swiss Firm Of G Laubscher & Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/155Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/12Pressure infusion

Definitions

  • This invention relates to the transfusion of vblood plasma, full blood, blood-replacing liquid or serum into human or animal bodies and has for its primary object to provide anew or improved instrument oi very simple, light and portable character lending itself to easy manipulation by practitioners, .physicians or veterinary surgeons.
  • Another object of the invention is to provide a new instrument as aforesaid capable of being readily manipulated by the practitioner singlehanded, the transfusable liquid being gradually forced out of a flexible receptacle ⁇ containing the same either by gravity or by a stress exerted with particular advantage through an iniiatable actuator such as an air bag arranged inside or outside said receptacle and adapted to progressively contract its wall so as to lessen its volume.
  • an iniiatable actuator such as an air bag arranged inside or outside said receptacle and adapted to progressively contract its wall so as to lessen its volume.
  • a further object of the invention is to provide a new instrument as aforesaid wherein the means conducting the liquid from its storage receptacle .to the transfusion point incorporate a lter whereby said liquid enters the live body in such an optically homogeneous and purecondition as to minimize the risk oi embolism or like accidents.
  • a still further object of the invention is to provide a new instrument as aforesaid wherein the filter has a progressive effect and is so retained in a readily dismountable casing adaptable to the liquid receptacle as to lend itself to easy interchange or cleaning.
  • FIG. 1 is an elevational view partly broken away of a transfusion instrument representing the first embodiment of the invention.
  • Figures 2 vand 3 are two different views of an instrument similar to the one shown in Figure l but provided with a stepped filter and representing the second embodiment of the invention.
  • Figure 4 is a separate view of a constructional detail of the instrument shown in Figures 2 and 3.
  • Figures 5 and 6 are respectively an elevational view and a sectional view of a twin rubber bag unit belonging to the instrument shown in Figures 2 and 3.
  • Figure '7 is an elevational view of a twin rubber bag unit belonging to an instrument representing the third embodiment of the invention.
  • the instrument for the transfusion of blood plasma, full blood and blood-replacing liquid or serum comprises a receptable constituted by a rubber bag a provided with a perforated suspension lug al and adapted to receive the transfusable liquid.
  • the mouth of the bag a has tted therein a flanged threaded bushing b. Between the annular ilange b1 of said bushing and a at nutJ c are clamped the peripheral edge of the bag mouth and a holding ring d provided with a pair of diametrically opposed bails dl, d1.
  • the threaded bushing b is conically splayed out at its outer end to provide a seat into which is tightly tted a cooperating seat formed o-n a beaded nipple k held against said bushing by va screwed cap e.
  • the nipple ⁇ lc has an olive-shaped mouthpiece upon which may be frictionally held the one end of a rubber or like hose f whose opposite end is connected through a thick walled glass tube g and a valve or cock h with a transfusion or injection hollow needle i interchangeably tted upon the body of the cock h and protected, when not in use, by a suitable hood il.
  • the screwed cap e may be replaced by some suitable form of tapped cover (not shown) which can be screwed into tight itting engagement upon the screw-threaded bushing b, thereby permitting the rubber bag a to be used not only vfor immediate transfusion of blood or another transfusable liquid but also for transporting or keeping said blood or liquid stored.
  • the rubber bag a is advantageously so sized as to enable a quantity of vtransfusable liquid up to 600 cubic centimeters to be either transfused or preserved in stored condition for subsequent use.
  • an instrumen-t built as above stated presents great advantages for practitioners because it combines the possibility of transfusing blood or blood-replacingr liquid such for example as serum Without hindrances with the further possibility of conveniently transporting the same in a non-brittle container and of preserving blood away from outer air access under conditions of utmost safety. Therefore, .this improved instrument is particularly well adapted for use either in clinical hospitals or for countryside practitioners or physicians orl else for veterinary surgery.
  • the instrument comprises likewise a flexible sealed bag a having its mouth provided with a threaded L-shaped bushing b upon which may be screwed up for the purpose of transporting the bag filled with liquid a ltapped cover c1 ( Figure 3).
  • the instrument also comprises a stepped lter accommodated in a casing q and including a stack of three perforated metal disks q1, as shown in Figure 4. Between said disks are interposed ⁇ filtering layers of a material such for example as silk gauze having different thicknesses, said thicknesses increasing in the downward direction, i, e.
  • the superimposed fil-tering layers are arranged in the cylindrical portion of the casing q, the latter surmounting its ytapering portion ending in the nipple q2. Said filtering layers are securely held in proper position in said casing by a wedged in expansion ring p.
  • the casing q is provided at its upper end with an upstanding rim v having an outer flaring wall forming a seat adapted to cooperate with the seat formed by the inner wall of .the threaded bushing b when the filter unit is connected up to the bag a.
  • Said filter unit is securely and removably held in its connected relation to the bag a by a screwed cap m having an inner shape matching ⁇ the outer shape of the casing q and adapted to be screwed upon the threaded bushing b.
  • Over the olive-shaped nipple q2 may be frictionally engaged the one end of a rubber hose f whose opposite end communicates through a short glass tube g with the barrel of a closing off valve or cock h to which an injection needle i is interchangeably fitted, the tip of said needle being protected when it is not being used by a hood i1.
  • a tting on a hose connected to an injection needle may be substituted for the tapped cover c1.
  • a smaller air bag b3 also made of rubber which can be inflated from a small pump constituted by a hollow rubber ball c3 and connected thereto by a hose c4.
  • FIG. '7 is shown a modification representing a reverse combination of lthe two bags.
  • the inner bag m1 is adapted to contain the transfusable liquid, while lthe outer bag n can be inflated to so flexibly distort the wall of the bag m1 as to drive ythe liquid therefrom towards the injecting needle (not shown).
  • Both bags m1 and n are advantageously made of rubber.
  • An instrument for the transfusion oi liquids such as blood plasma, whole blood and serum, comprising a primary sealed rubber bag having a mouth, a flanged threaded bushing fitted in said mouth, a secondary sealed rubber bag surrounding the primary bag and so associated therewith as to constrict its volume when inflated, means for inflating said secondary bag, said bushing being splayed out to form a seat, a nut screwed on said bushing, a ring clamped together with the peripheral edge of the bag mouth intermediate the bushing flange and said nut, said ring having diametrically opposed bails, a combination lter and outlet nipple having a seat matching the bushing seat to cooperate therewith, a screw cap engageable over said nipple and threadable to said bushing, and means for conducting the liquid from said bag and nipple .to the transfusion point.
  • a primary sealed rubber bag having a mouth, a flanged threaded bushing fitted in said mouth, a

Description

Oct.'22, 1946; R. BUCHYER INSTRUMENT FOR BLOOD TRANSFUSION Filed Sept. 4, 1942 s sheets-sheet 1 4Oct. 22, 1946. R. BucHE f l 2,409,734.
K INSTRUMENT FOR BLOOD TRANSFUSION Filed Sept. '4, 1942 5 Sheets-Sheet 2 Oct. 22, 1946. R. BUCHER I INSTRUMENT FOR BLOOD TRANSFUSION s lsheets-sheet s Filed sept. 4, -1942 Patented Oct. 22, 1946 INSTRMENT FOR BLOOD TRANSFUSIN Rudolf Bucher, Basel, Switzerland, assgnor to the Swiss firm of G. Laubscher & Co., Basel, Switzerland Application September 4, 1942, Serial No. 457,340 In Switzerland September 20, 1941 2 claims. (ci. 12s- 214) This invention relates to the transfusion of vblood plasma, full blood, blood-replacing liquid or serum into human or animal bodies and has for its primary object to provide anew or improved instrument oi very simple, light and portable character lending itself to easy manipulation by practitioners, .physicians or veterinary surgeons.
Another object of the invention is to provide a new instrument as aforesaid capable of being readily manipulated by the practitioner singlehanded, the transfusable liquid being gradually forced out of a flexible receptacle` containing the same either by gravity or by a stress exerted with particular advantage through an iniiatable actuator such as an air bag arranged inside or outside said receptacle and adapted to progressively contract its wall so as to lessen its volume.
A further object of the invention is to provide a new instrument as aforesaid wherein the means conducting the liquid from its storage receptacle .to the transfusion point incorporate a lter whereby said liquid enters the live body in such an optically homogeneous and purecondition as to minimize the risk oi embolism or like accidents. i
A still further object of the invention is to provide a new instrument as aforesaid wherein the filter has a progressive effect and is so retained in a readily dismountable casing adaptable to the liquid receptacle as to lend itself to easy interchange or cleaning.
With these and such other objects in view as will incidentally appear hereafter, the invention comprises the novel construction and combination of parts that will now be described with reference to the accompanying diagrammatic drawings illustrating three convenient exemplifying embodiments thereof and forming a part of the present disclosure.
In the drawings- Figure 1 is an elevational view partly broken away of a transfusion instrument representing the first embodiment of the invention.
Figures 2 vand 3 are two different views of an instrument similar to the one shown in Figure l but provided with a stepped filter and representing the second embodiment of the invention.
Figure 4 is a separate view of a constructional detail of the instrument shown in Figures 2 and 3.
Figures 5 and 6 are respectively an elevational view and a sectional view of a twin rubber bag unit belonging to the instrument shown in Figures 2 and 3.
Figure '7 is an elevational view of a twin rubber bag unit belonging to an instrument representing the third embodiment of the invention.
Like reference characters designate like parts throughout the Several views.
As shown in Figure l, the instrument for the transfusion of blood plasma, full blood and blood-replacing liquid or serum comprises a receptable constituted by a rubber bag a provided with a perforated suspension lug al and adapted to receive the transfusable liquid. The mouth of the bag a has tted therein a flanged threaded bushing b. Between the annular ilange b1 of said bushing and a at nutJ c are clamped the peripheral edge of the bag mouth and a holding ring d provided with a pair of diametrically opposed bails dl, d1. The threaded bushing b is conically splayed out at its outer end to provide a seat into which is tightly tted a cooperating seat formed o-n a beaded nipple k held against said bushing by va screwed cap e. The nipple `lc has an olive-shaped mouthpiece upon which may be frictionally held the one end of a rubber or like hose f whose opposite end is connected through a thick walled glass tube g and a valve or cock h with a transfusion or injection hollow needle i interchangeably tted upon the body of the cock h and protected, when not in use, by a suitable hood il.
It will be understood that by holding the rubber bag a at the required height or by hanging it up by means of its suspension lug a1 the blood to be transfused may be caused to flow through the rubber hose f, glass tube g and needle i and that such bag ensures proper uniform and unobstructed outflow of the transfusable liquid following its constantly diminishing capacity, without calling for the intake of atmospheric air.
After removal of the nipple 7c and associated parts, the screwed cap e may be replaced by some suitable form of tapped cover (not shown) which can be screwed into tight itting engagement upon the screw-threaded bushing b, thereby permitting the rubber bag a to be used not only vfor immediate transfusion of blood or another transfusable liquid but also for transporting or keeping said blood or liquid stored.
So far as its capacity is concerned, the rubber bag a is advantageously so sized as to enable a quantity of vtransfusable liquid up to 600 cubic centimeters to be either transfused or preserved in stored condition for subsequent use.
As above set forth, an instrumen-t built as above stated presents great advantages for practitioners because it combines the possibility of transfusing blood or blood-replacingr liquid such for example as serum Without hindrances with the further possibility of conveniently transporting the same in a non-brittle container and of preserving blood away from outer air access under conditions of utmost safety. Therefore, .this improved instrument is particularly well adapted for use either in clinical hospitals or for countryside practitioners or physicians orl else for veterinary surgery.
Reference being now made to Figures 2 and 3, it will be seen tha-t the instrument comprises likewise a flexible sealed bag a having its mouth provided with a threaded L-shaped bushing b upon which may be screwed up for the purpose of transporting the bag filled with liquid a ltapped cover c1 (Figure 3). In this embodiment, .the instrument also comprises a stepped lter accommodated in a casing q and including a stack of three perforated metal disks q1, as shown in Figure 4. Between said disks are interposed` filtering layers of a material such for example as silk gauze having different thicknesses, said thicknesses increasing in the downward direction, i, e. towards the lower olive-shaped outlet nipple q2 of the tapering casing q. On the uppermost ltering layer is laid a coarse sieve q3 made of wire net or gauze. The superimposed fil-tering layers are arranged in the cylindrical portion of the casing q, the latter surmounting its ytapering portion ending in the nipple q2. Said filtering layers are securely held in proper position in said casing by a wedged in expansion ring p. The casing q is provided at its upper end with an upstanding rim v having an outer flaring wall forming a seat adapted to cooperate with the seat formed by the inner wall of .the threaded bushing b when the filter unit is connected up to the bag a. Said filter unit is securely and removably held in its connected relation to the bag a by a screwed cap m having an inner shape matching `the outer shape of the casing q and adapted to be screwed upon the threaded bushing b.
Over the olive-shaped nipple q2 may be frictionally engaged the one end of a rubber hose f whose opposite end communicates through a short glass tube g with the barrel of a closing off valve or cock h to which an injection needle i is interchangeably fitted, the tip of said needle being protected when it is not being used by a hood i1.
When carrying out a blood transfusing operation by means of the present instrument, .the
blood percolates through the several filtering layers and reaches the injection needle i in an optically homogeneous coagulate-free condition, thus surely obviating the risk of embolism owing to impurities arising from coagulation,
Reference being now made to Figures 5 and 6, I
it will be seen that a still designates the rubber bag `adapted to receive the .transfusable liquid and provided at its upper end with a perforated suspension lug a1 and at its lower end with a tight closure including a tapped cover c1. As above stated and as illustrated in broken lines,
a tting on a hose connected to an injection needle may be substituted for the tapped cover c1. Inside the bag a is provided a smaller air bag b3 also made of rubber which can be inflated from a small pump constituted by a hollow rubber ball c3 and connected thereto by a hose c4. By inating the smaller or inner air bag b3, the volume of the larger or outer bag a capable of receiving `the transfusable liquid is reduced whereby said liquid is forced out and transfused through the injection needle.
In Figure '7 is shown a modification representing a reverse combination of lthe two bags. The inner bag m1 is adapted to contain the transfusable liquid, while lthe outer bag n can be inflated to so flexibly distort the wall of the bag m1 as to drive ythe liquid therefrom towards the injecting needle (not shown). Both bags m1 and n are advantageously made of rubber.
Minor constructional details of the instrument might be changed without departing from the scope of the subjoined claims.
What I claim is:
1. An instrument for the transfusion of liquids, such as blood plasma, whole blood and serum, comprising a primary sealed rubber bag having a mouth, a flanged threaded bushing tted in said mouth, a secondary sealed rubber bag so associated with the primary bag as to contract the volume of the latter when iniated, means for inlating said secondary bag, said bushing being splayed out to form a seat, a nut screwed on said bushing, a ring clamped together with the peripheral edge of the bag mouth intermediate the bushing ange and said nut, said ring having diametrically opposed bails, a combination filter and outlet nipple having a seat matching the bushing seat to cooperate therewith, a screw cap engageable over said nipple and threadable to said bushing, and means for conducting the liquid from said bag and nipple =to the transfusion point.
2. An instrument for the transfusion oi liquids, such as blood plasma, whole blood and serum, comprising a primary sealed rubber bag having a mouth, a flanged threaded bushing fitted in said mouth, a secondary sealed rubber bag surrounding the primary bag and so associated therewith as to constrict its volume when inflated, means for inflating said secondary bag, said bushing being splayed out to form a seat, a nut screwed on said bushing, a ring clamped together with the peripheral edge of the bag mouth intermediate the bushing flange and said nut, said ring having diametrically opposed bails, a combination lter and outlet nipple having a seat matching the bushing seat to cooperate therewith, a screw cap engageable over said nipple and threadable to said bushing, and means for conducting the liquid from said bag and nipple .to the transfusion point.
RUDOLF BCHER.
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Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2617359A (en) * 1951-11-16 1952-11-11 George E Van Horn Hypodermic projectile
US2642866A (en) * 1951-02-03 1953-06-23 Arthur F Smith Blood container and method of making the same
US2647514A (en) * 1951-06-29 1953-08-04 American Optical Corp Apparatus for collecting and preserving blood
US2653606A (en) * 1949-07-06 1953-09-29 George R Ryan Transfusion apparatus
US2663298A (en) * 1950-06-16 1953-12-22 Hilton W Rose Apparatus and method for administering parenteral solutions
US2702034A (en) * 1950-07-20 1955-02-15 Fenwal Inc Apparatus for collecting, storing, and dispensing whole blood
US2761445A (en) * 1952-05-03 1956-09-04 Baxter Don Inc Apparatus for regulating fluid flow
US2764452A (en) * 1954-06-28 1956-09-25 Anderson Denton Sprayer
US2839056A (en) * 1955-03-01 1958-06-17 Jouan S A Ets Device for administering and transfusing blood, serums, plasmas and other medicinal preparations
US3023750A (en) * 1959-03-04 1962-03-06 Howard C Baron Self-generating pressure device for infusion administration systems
US3054401A (en) * 1959-12-23 1962-09-18 American Sterilizer Co Transfusion set
US3153414A (en) * 1962-02-02 1964-10-20 Abbott Lab Apparatus for the induced infusion of liquid from a flexible liquid container
US3228395A (en) * 1961-11-10 1966-01-11 Mcgaw Lab Inc Blood bag transfusion unit with pressure chamber
US3584770A (en) * 1969-01-28 1971-06-15 Philip Taylor Intravenous bottle having expandable inner receptacle
US3838794A (en) * 1972-07-10 1974-10-01 H Markham Package for storing and dispensing liquids
US4033345A (en) * 1975-11-13 1977-07-05 Sorenson Research Co., Inc. Autologous transfusion filter system and method
US4048994A (en) * 1976-08-24 1977-09-20 Lo Liu Ying P Self-inflating liquid container for keeping I.V. fluid or blood plasma
US4379453A (en) * 1978-12-28 1983-04-12 Baron Howard C Infusion system with self-generating pressure assembly
EP0094998A1 (en) * 1982-05-24 1983-11-30 Staodynamics Inc. Positive displacement intravenous infusion pump device and method
US20070244466A1 (en) * 2006-04-12 2007-10-18 Fangrow Thomas F Vial adaptor for regulating pressure
US20080249498A1 (en) * 2007-03-09 2008-10-09 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
US20100049157A1 (en) * 2008-08-20 2010-02-25 Fangrow Thomas F Anti-reflux vial adaptors
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
US9132062B2 (en) 2011-08-18 2015-09-15 Icu Medical, Inc. Pressure-regulating vial adaptors
US9610217B2 (en) 2012-03-22 2017-04-04 Icu Medical, Inc. Pressure-regulating vial adaptors
US9615997B2 (en) 2013-01-23 2017-04-11 Icu Medical, Inc. Pressure-regulating vial adaptors
US9987195B2 (en) 2012-01-13 2018-06-05 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US10201476B2 (en) 2014-06-20 2019-02-12 Icu Medical, Inc. Pressure-regulating vial adaptors
US10292904B2 (en) 2016-01-29 2019-05-21 Icu Medical, Inc. Pressure-regulating vial adaptors
US10406072B2 (en) 2013-07-19 2019-09-10 Icu Medical, Inc. Pressure-regulating fluid transfer systems and methods
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Cited By (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653606A (en) * 1949-07-06 1953-09-29 George R Ryan Transfusion apparatus
US2663298A (en) * 1950-06-16 1953-12-22 Hilton W Rose Apparatus and method for administering parenteral solutions
US2702034A (en) * 1950-07-20 1955-02-15 Fenwal Inc Apparatus for collecting, storing, and dispensing whole blood
US2642866A (en) * 1951-02-03 1953-06-23 Arthur F Smith Blood container and method of making the same
US2647514A (en) * 1951-06-29 1953-08-04 American Optical Corp Apparatus for collecting and preserving blood
US2617359A (en) * 1951-11-16 1952-11-11 George E Van Horn Hypodermic projectile
US2761445A (en) * 1952-05-03 1956-09-04 Baxter Don Inc Apparatus for regulating fluid flow
US2764452A (en) * 1954-06-28 1956-09-25 Anderson Denton Sprayer
US2839056A (en) * 1955-03-01 1958-06-17 Jouan S A Ets Device for administering and transfusing blood, serums, plasmas and other medicinal preparations
US3023750A (en) * 1959-03-04 1962-03-06 Howard C Baron Self-generating pressure device for infusion administration systems
US3054401A (en) * 1959-12-23 1962-09-18 American Sterilizer Co Transfusion set
US3228395A (en) * 1961-11-10 1966-01-11 Mcgaw Lab Inc Blood bag transfusion unit with pressure chamber
US3153414A (en) * 1962-02-02 1964-10-20 Abbott Lab Apparatus for the induced infusion of liquid from a flexible liquid container
US3584770A (en) * 1969-01-28 1971-06-15 Philip Taylor Intravenous bottle having expandable inner receptacle
US3838794A (en) * 1972-07-10 1974-10-01 H Markham Package for storing and dispensing liquids
US4033345A (en) * 1975-11-13 1977-07-05 Sorenson Research Co., Inc. Autologous transfusion filter system and method
US4048994A (en) * 1976-08-24 1977-09-20 Lo Liu Ying P Self-inflating liquid container for keeping I.V. fluid or blood plasma
US4379453A (en) * 1978-12-28 1983-04-12 Baron Howard C Infusion system with self-generating pressure assembly
EP0094998A1 (en) * 1982-05-24 1983-11-30 Staodynamics Inc. Positive displacement intravenous infusion pump device and method
US8945084B2 (en) 2006-04-12 2015-02-03 Icu Medical, Inc. Pressure-regulating vial adaptors and methods
US10327993B2 (en) 2006-04-12 2019-06-25 Icu Medical, Inc. Vial access devices
US7354427B2 (en) * 2006-04-12 2008-04-08 Icu Medical, Inc. Vial adaptor for regulating pressure
US20080161770A1 (en) * 2006-04-12 2008-07-03 Fangrow Thomas F Vial adaptor for regulating pressure
US11696871B2 (en) 2006-04-12 2023-07-11 Icu Medical, Inc. Devices for accessing medicinal fluid from a container
US7507227B2 (en) 2006-04-12 2009-03-24 Icu Medical, Inc. Vial adaptor for regulating pressure
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US8206367B2 (en) 2006-04-12 2012-06-26 Icu Medical, Inc. Medical fluid transfer devices and methods with enclosures of sterilized gas
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US20070244462A1 (en) * 2006-04-12 2007-10-18 Fangrow Thomas F Vial adaptor for regulating pressure
US10327989B2 (en) 2006-04-12 2019-06-25 Icu Medical, Inc. Devices and methods for transferring fluid to or from a vial
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