US2474496A - Syringe - Google Patents
Syringe Download PDFInfo
- Publication number
- US2474496A US2474496A US757253A US75725347A US2474496A US 2474496 A US2474496 A US 2474496A US 757253 A US757253 A US 757253A US 75725347 A US75725347 A US 75725347A US 2474496 A US2474496 A US 2474496A
- Authority
- US
- United States
- Prior art keywords
- plunger
- syringe
- fluid
- barrel
- clip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
Definitions
- Another object of the invention resides in the provision of a resilient means in combination with an injection syringe whereby a pre-determined unit or units of fluid may be extruded from the syringe without necessitating visual examination of the syringe.
- Figure 1 is an elevational view of the syringe of the hypodermic type embodying a form of my invention
Description
June 28, 1949. I L. RAYMANII 2,474,496
SYRINGE Filed June 26, 1947 T INVENTOR. Lawrence l-Fayman I Patented June 28, 1949 UNITED STATES- Application June 26,
1 Claim. (Cl. 128-218) This invention relates to fluid injecting devices and more especially to devicesof the syringe type for the injection of medicament or composition in hypodermic or intravenous injections.
The invention embraces the provision of means in combination with a fluid injection syringe whereby the amount of fluid to be drawn into or extruded from the syringe may be accurately determined.
An object of the invention is the provision of means engageable with spaced abutments or depressions formed on a syringe plunger for interrupting or retarding movement of the plunger, the spaces between the abutments or depressions representing pre-determined units of volume of contents in the syringe for injection purposes.
Another object of the invention is the provision of resilient means associated with a barrel of a syringe and cooperable with a serrated plunger for pre-determining by feel of the plunger movement the dosage of medicament or fluid ejected from the syringe.
Another object of the invention resides in the provision of a resilient means in combination with an injection syringe whereby a pre-determined unit or units of fluid may be extruded from the syringe without necessitating visual examination of the syringe.
Further objects and advantages are within the scope of this invention such as relate to the arrangement, operation and function of the related elements of the structure, to various details of construction and to combinations of parts, elements per se, and to economies of manufacture and numerous other features as will be apparent from a consideration of the specification and drawing of a form of the invention, which may be preferred, in which:
Figure 1 is an elevational view of the syringe of the hypodermic type embodying a form of my invention;
Referring to the drawings in detail, the syringe PATIENT OFFICE 2,474,49 SYRINGE Lawrence Rayman, Toledo, Ohio 1947, Serial No. 757,253
construction is inclusive oi a cylindrically shaped member or barrel I fabricated of glass or other suitable material which has a hollow interior forming a tubular or cylindrical chamber H. The barrel I0 is adapted to snugly yet slidably receive a plunger l2 also formed of glass or other suitable material. The plunger l2, while of a diameter permitting slidable movement of the plunger in the barrel [0, provides only a slight clearance space between-the plunger and the interior wall of the barrel which is insufiicient to permit fluid to flow barrel and plunger. The barrel l3 terminates at one end in a nipple M which is formed with a slightly tapered exterior surface arranged to frictionally receive the hollow shank portion l5 of a hypodermic needle [6. The needle [6 is formed with a very minute longitudinal channel I! to permit the passage of fluid therethrough. The nipple I4 is provided with a channel [8 for establishing communication between the channel I! of the needle and the interior of chamber II.
The exterior wall of the barrel I0 is provided with graduations or indications 25 in the form of lines inscribed transversely of the barrel It for indicating quantities of fluid that may be contained within the chamber II. The graduations 20 provide a visual means for informing the user of the syringe as to the amount of fluid or material in the chamber H and serves visually to advise the user of the amount of fluid ejected from the chamber by movement of the plunger l2.
The plunger I2 is formed at its outer extremity with a thumb piece or button portion 22 which is integrally joined to the body portion by means of a tenon 23 of slightly reduced diameter. My invention is inclusive of simple yet effective means for mechanically informing the user of the syringe of the withdrawing or ejection of a pre-determined unit or amount of fluid. In accomplishing this result, the plunger I2 is provided with spaced circular depressions or recesses 24 formed in stacked alinement in the cylindrical exterior surface of the plunger. Means is provided resiliently engageable with the recesses for mechanically. determining the ex- .tent of movement of the plunger 12 during a fluid ejecting operation. The mouth portion of the barrel 40 which is adapted to receive the plunger I2 is formed with spaced ridges or beads 26 and 21 forming together a circular recess or depression 28. A resilient clip or member 29, arranged for cooperation with the plunger 12 55 for fluid measuring purposes, is formed with an between the walls of the annular portion 30 extending throughout a major portion circumferentially of the barrel l0 and is disposed in the recess 28 formed by the beads or ridges 26 and 21. The clip 29 is preferably formed of spring wire or other suitable material having resilient characteristics so that the inherent tension or stress in portion 30 serves to hold the clip in close frictional engagement in the recess-"28?: andt preuent dislodgment of the clip. Ilhexclip 29 is of a cantilever :typerideing formed 'with a radially extending portion 32 which takes over the head 21 and is bent in the opposite direction as shown as 33 to form a V- shaped configuration as indicated in Figure 2,
being arranged for slidable contact with the sion or inherent stress in the Wire orimetaliof the clip serves to resiliently maintain the apex .34. at all times. in frictional contact with the plunger! 2.
".In the use of the construction shown :in Figlures" l throu'gh23.inclusivefthe'user'inserts the '..nee.dle"I6' into .a receptacle containing fluidror medicament with the. plunger 'telescoped to'its .;in-nermost position 'withinathe' .barr'el "Ill. .The .iplunger. 12 .isjthen' withdrawn relative to the cyliinder whilethenee'dle' 16 is inserted in'the' fluid, lthe'jflnid.being..thereby sucked up or aspirated ..into.'-.the..chamher I I. ll'he'distancesbetween the .iserraticnslld. .formedqinlthe plunger 'of the. barrel ..are...made equivalent tqapresdetermined units. of evolumenofnfluidrinIthe' chamber .II. 'IThus, for .aexample, .the distance. between. adjacent recesses :'Z4,.-may .be thenequivalentlin .volume .to onehalf" icubicwcentimeter offluidiinthe chamber H. It vista. be understoodthat anytother unit. of. meas- .ureme-ntmay @be employed. Theimarkshor serra- ..-tions 2H. disposed on. the. exterior surface of .the .barrel. I i). may also betca-librated to the same volu- :"Inetric -.units.- as those; indicated.. by the. distances wbetween the serrations IOTaFGCBSSSS '24 on the -.-plunger1 l2. Asutheplunger l2 isawithdrawndn ea rig-ht 'hand directionas .viewedin. Figure 1', .to -=cause-. =fl-uid= withoutturning the plunger to .sbe
ldrawn. into' the chamber l lntheeapexi l of .the
..clip "29 registers with :each consecutive recessr24 -zso thatuthenuser iseinformedlby the .feel :or I -added re'sistance rtoithe plunger movement whenweverthe apex 34 engagesinza recess. If more .\than.. one .unitof fluiduindicated by the distance between successive recesses is desired, thenuser *exents further outward.-.force upontthe: plunger 12 .to* disengagetheapex-M- of the'clip with-1a.; rec ess and; "upon :further movement of the plung- 55 .er, .the :clip will again engage with the". next successive recess. -.The resistance to further moveunent: :ofttha plunger: gagain. rindicates I to the user .athatai second. unit. of 'volume 'i'Ofi fluid :has been "drawn intothe chamber .1. l.
During ejection of .thetifluid :from the :syrirrge, --.t'he"l'uSe1'"'0f the syringe :exerts 1pressure upon 1the tithumb *piece .22 of :the.;plunger.- without turning .ithe zsame to force .;the' plunger 1 21in a .lieftphand; adire ction as viewed in" Figure 1 :eausingnthe plunger ato extrudet for: eject fluid; from .thercham'ber. :l I. iThezuseriof ttheisyringe Willrimmediately. notice aanyincreaserin-.resistancerto .the" movement ofithe oplungenuntil the apex 34 has heenrmoved "out-50f szengagement "with :one'are'cess. After this 1diseng gagementis efiected;thepressure-required:to. move tithe plunger is-.-decreased..=iAssoon as. the. next sucperiphery of the plunger I2."- The- 'spring ten- .4 ceeding recess 24 is moved into registration with the apex 34 of the clip, the movement of travel of the plunger will be temporarily interrupted because of the resilient force exerted by the clip in urging the apex 34 thereof into a recess or detent 24. This increase in resistance to movement of the plunger informs the user of the syringe that a pre-determined unit of fluid has been ejectfledrirom theisyrinee. .iByrthisrmeans zthe syringe but also by patients administering injections to irthemselves, as the desired dosage may be had independently of visual inspection of the graduations on the barrel. Thus a patient having defo min an apex or bi ht p0rti 4 v nl. 'zefeclxive eymlsight is enabled to use the syringe .:and efiectan. injection of a pre-determined unit ort-units---bf-"m'edicament through the aid of mechanical measuring means for determining the quantity of fluid ejected from the syringe.
2o l..If.. desired the recesses or. depressions may. ex-
. .tend...only partiallyrraround; the barrel. T12. :As shownJnZFEigurei; jthe' recesses 2'4. extend only partially. amundi'the Lplunger. 'ZfThusjiL it is. .de-
.. sired to utilize lthe;syringe. without .emp10yil1g;the
" 25' recessessassmeasuring' means, the plunger. may
s, be emtatedsto. bringilthe' iclipfs'29i out. of .the locus of thelrecesses.
' In both 'forms of"the'inve'ntion, the clip;29..not
nonly=serves as. a :means.forsmechanicallumeasur- .from a syringe,- b.ut..'a1so' functions. .as a. friction means. to; preuenthinaiduertent removal, of. :the lplungerirom the. .ha1:r'e1 .lllv whenv the syringelis :inverted.
"35 ...It.;.is,i. apparent. that, .:within the scope .of the Qntionslthereof.
What I claim is: i A, llypodermic'syringercomprisingt a. barrel porstionmanm a plungersxisaidmlunger having 7 a plusralitystof graduations .iormed :thereorr extending acireumierentiallythereaboutt-saidgraduationsbeingsin; ithe; 1form iofisedepressions formed. -on.- the plunger, said depressionsmbeing icoextensive. in -'.length and insstackedzalinement; :saidtbarrel porstionahaving a -.resilient.-icantilever :type .clip with .-..convergingliclip;lelements storming a bight :por- ..;.tion :molunte'd sexternallysthereon; the. bight.- .portion, of rsaiclr-iclipel-engaging. the: peripheryof. the uplungenwhich extends outside of said barrel-por- Mtiona'and; adaptedzto'zcooperatewithgsaida depres- :sions *in :2 the .plungemwhenl the. plunger .is moved .rinwardly; zon-zoutwlardly dim a' straight line movement for resiliently snestraining -at 1 the. depressed .;-..-portions :':the :longitudmal:rdisplacement:utofii the gziplunger. therebyafacilitating :rmeasurement rof units of fluid drawn into or ejented zfrom "said -fhEfl-Bl.
rLAWRENCEIaRAYMAN.
L-BEFERENCESJC ITED mi -Number Name 'Date 1,546,494 liangbein July '2l; 1925 2,373,520 '-Wa'1lin Apr. "10, 1 945
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US757253A US2474496A (en) | 1947-06-26 | 1947-06-26 | Syringe |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US757253A US2474496A (en) | 1947-06-26 | 1947-06-26 | Syringe |
Publications (1)
Publication Number | Publication Date |
---|---|
US2474496A true US2474496A (en) | 1949-06-28 |
Family
ID=25047061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US757253A Expired - Lifetime US2474496A (en) | 1947-06-26 | 1947-06-26 | Syringe |
Country Status (1)
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US (1) | US2474496A (en) |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2764981A (en) * | 1955-09-01 | 1956-10-02 | Norman D Helmer | Multiple dosage syringe |
US2856925A (en) * | 1956-01-13 | 1958-10-21 | Easton | Syringe structure |
US3934586A (en) * | 1975-01-22 | 1976-01-27 | Easton Fred H | Non-refillable multiple dosage syringe |
FR2536285A1 (en) * | 1982-11-18 | 1984-05-25 | Buttigieg Charles | Improved syringe with a controllable locking position |
US4466426A (en) * | 1981-06-29 | 1984-08-21 | Blackman Seymour N | Syringe with actinic ray blocking stripe |
US4874385A (en) * | 1987-12-16 | 1989-10-17 | Sherwood Medical Company | Plunger lock device |
WO1989010151A1 (en) * | 1988-04-18 | 1989-11-02 | Nujenko Pty Ltd | Single-use syringe |
US4946069A (en) * | 1987-10-10 | 1990-08-07 | Ing. Erich Pfeiffer Gmbh & Co. Kg | Dispenser for manually discharging flowable media |
US5279582A (en) * | 1992-04-01 | 1994-01-18 | Thomas R Davison | Retractable syringe sheath with bottle engagement |
US5328484A (en) * | 1992-08-12 | 1994-07-12 | Brice Somers | Non-reusable syringe for medical purposes |
US5501373A (en) * | 1991-08-02 | 1996-03-26 | R.G.S.A.S.Di Rosaria Galli & C | Atomizing dispenser for endonasal drug spray administration |
EP0711571A1 (en) * | 1994-05-31 | 1996-05-15 | Keytron Co., Ltd. | Injector type atomizer |
US6110143A (en) * | 1998-06-25 | 2000-08-29 | Kamen; Jack M. | Inflation/deflation medical device |
US20030054379A1 (en) * | 2000-01-31 | 2003-03-20 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
US20030225358A1 (en) * | 2002-06-04 | 2003-12-04 | Berman Irwin R. | Focused dosimetry device and methods associated therewith |
US20040015120A1 (en) * | 2002-06-04 | 2004-01-22 | Berman Irwin R. | Focused dosimetry device and methods associated therewith |
US20050010174A1 (en) * | 2002-06-04 | 2005-01-13 | Berman Irwin R. | Applicator and methods of applying a substance |
US20060064602A1 (en) * | 2003-01-13 | 2006-03-23 | Frank Uittenbogaard | Navigating to content in a recording |
WO2011097742A1 (en) | 2010-02-12 | 2011-08-18 | Medmix Systems Ag | Discharge device having a locking element |
WO2012174670A1 (en) | 2011-06-22 | 2012-12-27 | Medmix Systems Ag | Device for low-bubble mixing and discharge of a product |
USD750768S1 (en) | 2014-06-06 | 2016-03-01 | Anutra Medical, Inc. | Fluid administration syringe |
US9387151B2 (en) | 2013-08-20 | 2016-07-12 | Anutra Medical, Inc. | Syringe fill system and method |
USD763433S1 (en) | 2014-06-06 | 2016-08-09 | Anutra Medical, Inc. | Delivery system cassette |
EP3072547A1 (en) * | 2015-03-25 | 2016-09-28 | Q-Med AB | Track-indexed syringe |
USD774182S1 (en) | 2014-06-06 | 2016-12-13 | Anutra Medical, Inc. | Anesthetic delivery device |
US20180280613A1 (en) * | 2015-09-24 | 2018-10-04 | Vidacare LLC | Infusing devices, systems, and methods |
US10532163B2 (en) * | 2016-07-02 | 2020-01-14 | Gennady Kleyman | Fluid dispensing device |
US11013898B2 (en) | 2012-09-13 | 2021-05-25 | Syringe, Llc | Applicator for dispensing a medical substance and methods associated therewith |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1546494A (en) * | 1923-09-25 | 1925-07-21 | Langbein George | Syringe |
US2373520A (en) * | 1944-12-02 | 1945-04-10 | Wallin Loren | Hypodermic syringe |
-
1947
- 1947-06-26 US US757253A patent/US2474496A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1546494A (en) * | 1923-09-25 | 1925-07-21 | Langbein George | Syringe |
US2373520A (en) * | 1944-12-02 | 1945-04-10 | Wallin Loren | Hypodermic syringe |
Cited By (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2764981A (en) * | 1955-09-01 | 1956-10-02 | Norman D Helmer | Multiple dosage syringe |
US2856925A (en) * | 1956-01-13 | 1958-10-21 | Easton | Syringe structure |
US3934586A (en) * | 1975-01-22 | 1976-01-27 | Easton Fred H | Non-refillable multiple dosage syringe |
US4466426A (en) * | 1981-06-29 | 1984-08-21 | Blackman Seymour N | Syringe with actinic ray blocking stripe |
FR2536285A1 (en) * | 1982-11-18 | 1984-05-25 | Buttigieg Charles | Improved syringe with a controllable locking position |
US4946069A (en) * | 1987-10-10 | 1990-08-07 | Ing. Erich Pfeiffer Gmbh & Co. Kg | Dispenser for manually discharging flowable media |
US4874385A (en) * | 1987-12-16 | 1989-10-17 | Sherwood Medical Company | Plunger lock device |
WO1989010151A1 (en) * | 1988-04-18 | 1989-11-02 | Nujenko Pty Ltd | Single-use syringe |
US5501373A (en) * | 1991-08-02 | 1996-03-26 | R.G.S.A.S.Di Rosaria Galli & C | Atomizing dispenser for endonasal drug spray administration |
US5279582A (en) * | 1992-04-01 | 1994-01-18 | Thomas R Davison | Retractable syringe sheath with bottle engagement |
US5328484A (en) * | 1992-08-12 | 1994-07-12 | Brice Somers | Non-reusable syringe for medical purposes |
EP0711571A1 (en) * | 1994-05-31 | 1996-05-15 | Keytron Co., Ltd. | Injector type atomizer |
EP0711571A4 (en) * | 1994-05-31 | 1997-03-26 | Keytron Co Ltd | Injector type atomizer |
US6110143A (en) * | 1998-06-25 | 2000-08-29 | Kamen; Jack M. | Inflation/deflation medical device |
US20030054379A1 (en) * | 2000-01-31 | 2003-03-20 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
US7141036B2 (en) | 2002-06-04 | 2006-11-28 | Syringe, Llc | Methods of applying a medicinal substance |
US20040015120A1 (en) * | 2002-06-04 | 2004-01-22 | Berman Irwin R. | Focused dosimetry device and methods associated therewith |
US20050010174A1 (en) * | 2002-06-04 | 2005-01-13 | Berman Irwin R. | Applicator and methods of applying a substance |
US7125394B2 (en) | 2002-06-04 | 2006-10-24 | Syringe, Llc | Applicator for dispensing a medicinal substance |
US20030225358A1 (en) * | 2002-06-04 | 2003-12-04 | Berman Irwin R. | Focused dosimetry device and methods associated therewith |
US20070093746A1 (en) * | 2002-06-04 | 2007-04-26 | Berman Irwin R | Focused dosimetry device and methods associated therewith |
US20070179449A1 (en) * | 2002-06-04 | 2007-08-02 | Berman Irwin R | Applicator for dispensing a medicinal substance |
US8845596B2 (en) | 2002-06-04 | 2014-09-30 | Irwin R. Berman | Focused dosimetry device and methods associated therewith |
US20060064602A1 (en) * | 2003-01-13 | 2006-03-23 | Frank Uittenbogaard | Navigating to content in a recording |
WO2011097742A1 (en) | 2010-02-12 | 2011-08-18 | Medmix Systems Ag | Discharge device having a locking element |
WO2012174670A1 (en) | 2011-06-22 | 2012-12-27 | Medmix Systems Ag | Device for low-bubble mixing and discharge of a product |
US11013898B2 (en) | 2012-09-13 | 2021-05-25 | Syringe, Llc | Applicator for dispensing a medical substance and methods associated therewith |
US9393177B2 (en) | 2013-08-20 | 2016-07-19 | Anutra Medical, Inc. | Cassette assembly for syringe fill system |
US10010482B2 (en) | 2013-08-20 | 2018-07-03 | Anutra Medical, Inc. | Syringe fill system and method |
US9387151B2 (en) | 2013-08-20 | 2016-07-12 | Anutra Medical, Inc. | Syringe fill system and method |
US9579257B2 (en) | 2013-08-20 | 2017-02-28 | Anutra Medical, Inc. | Haptic feedback and audible output syringe |
US10010483B2 (en) | 2013-08-20 | 2018-07-03 | Anutra Medical, Inc. | Cassette assembly for syringe fill system |
USD763433S1 (en) | 2014-06-06 | 2016-08-09 | Anutra Medical, Inc. | Delivery system cassette |
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