US2535844A - Aspirator for administering medicine - Google Patents

Aspirator for administering medicine Download PDF

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US2535844A
US2535844A US68758646A US2535844A US 2535844 A US2535844 A US 2535844A US 68758646 A US68758646 A US 68758646A US 2535844 A US2535844 A US 2535844A
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chamber
pressure
nozzle
aspirator
gas
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John H Emerson
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/2496Self-proportioning or correlating systems
    • Y10T137/2514Self-proportioning flow systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/2496Self-proportioning or correlating systems
    • Y10T137/2544Supply and exhaust type

Definitions

  • This invention pertains to aspirators such as are employed in admin stering medical substances in spray form, for instance for inhalation by a patient, and in particular to an aspirator designed for use with medicaments which are too expensive to waste.
  • aspirators such as are employed in admin stering medical substances in spray form, for instance for inhalation by a patient
  • an aspirator designed for use with medicaments which are too expensive to waste for example penicillin has been found effective as an inha ant in the treatment of some forms of asthma, but at the present price of penicillin it is not available to many persons who would benefit from its use because of the wasteful methods of administration.
  • the object of the present invention is to provide apparatus of the type above referred to wherein a l quid medicament is atomized by a jet of compressed gas, for example oxygen, and having provision for the automatic limitation of the atomizing action to the period of inhalation, thus relieving the patient of the necessity of manipulating any control devices, and at the same time avoiding any waste of the expensive medicine.
  • Another object of the invention is to provide simple atomizing apparatus for the intended purpose and such as may be manufactured at a reasonable cost so as to make it generally available.
  • Fig. 2 is an edge elevation, partly broken away and to larger scale, showing details of the control mechanism with the parts in the position which they occupy during inhalation;
  • Fig. 3 is a view similar to Fig. 2 but showing the position of the parts during exhalation.
  • the numeral designates a casing of any suitable material, for instance a moulded plastic, glass or metal, delining a chamber 2, the lower part of which, in
  • the casing l is provided with a tubular branch 4 defining the delivery passage 5.
  • This branch 4 may be shaped to be held in the mouth of the patient or alternatively it may be shaped tofit into one nostril or into both nostrils.
  • the casing also has the tubular branch 6 providing the breathing port I, this port being of a size sufli'; cient to admit the passage of air in sufiicient quantity for breathing.
  • a jet nozzle 8 which is supplied with the medicinal substance from the body 3 by means of an elevat ng tube 9 supported by a rigid bracket It).
  • the upper end of the elevating tube is so arranged, relatively to the jet nozzle 8, that the aspirating effect of gas delivered from the jet nozzle lifts the medicinal substance to the nozzle tip so that the medicinal substance is atomized by the jet of gas issuing from the nozzle.
  • pressure motor l6 comprising a case I! which houses a very light and flexible diaphragm Hi.
  • the case defines a chamber l9, at one side of the diaphragm, which communicates by means of a tube 2E3 with the chamber 2 of the casing I. Since the chamber I9 of the pressure motor communicates with the chamber 2 of the casing i the diaphragm is responsive to pressure variations in the chamber 2. The right-hand side of the diaphragm is open to atmospheric pressure at all times.
  • the support I5 is provided with a discharge port/2! which is controlled by a movable valve head 22.
  • this valve head is carried by a lever 23 having an arm 23 which engages the central part of the diaphragm It; so that motion of the diaphragm causes the valve 22 to be seated or unseated.
  • valve means including a movable valve head operative alternatively to deliver gas to the nozzle or to vent the gas to the atmosphere and a pressure motor including a movable diaphragm which moves in one direction in response to exhalation pressure and in the other direction in response to inhalation pressure, and means so connecting the diaphragm and valve head that the valve head is actuated to vent the gas to the atmosphere, thereby to cease vaporization during periods of exhalation.
  • Apparatus for use in administering a medicinal substance in atomized form for inhalation by a patient comprising a vaporizing nozzle, and having provision, includ ing a constantly open, unobstructed conduit for supplying gas under pressure to said nozzle, said conduit having a vent port intermediate its ends, and a movable valve head operative at times to close said port, and automatic means responsive to exhalation pressure to open said valve thereby to vent the gas to the atmosphere at a point intermediate the ends of the conduit.
  • Apparatus for use in administering a medicinal substance in atomized form comprising means defining a chamber through which the patient inhales and exhales, the chamber having a constantly open aperture in its Wall of a size sufficient to pass air in the amount requisite for breathing, but such that the pressure in the chamber decreases and increases slightly in response to inhalation and exhalation respectively, a nozzle arranged to discharge the atomized medicinal substance into the chamber, a constantly open unobstructed conduit for leading gas under pressure from the source of supply to the nozzle, and means responsive to exhalation pressure Within the chamber to vent the gas on its way from the supply to the nozzle to the outer atmosphere.

Description

Dec. 26, 1950 J. H. EMERSON 2,535,844
ASPIRATOR FOR ADMINISTERING MEDICINE Filed Au 1, 1946 I 722162241502" T157272 HZ/mersmz z 8 6 M J Attys Patented Dec. 26, 1950 UNITED STATES PATENT OFFICE ASPIRATOR FOR ADli/IINISTERING MEDICINE John H. Emerson, Cambridge, Mass.
Application August 1, 1946, Serial No. 687,586
(Cl. Mil-"195) 10 Claims. 1
This invention pertains to aspirators such as are employed in admin stering medical substances in spray form, for instance for inhalation by a patient, and in particular to an aspirator designed for use with medicaments which are too expensive to waste. For example penicillin has been found effective as an inha ant in the treatment of some forms of asthma, but at the present price of penicillin it is not available to many persons who would benefit from its use because of the wasteful methods of administration.
It has heretofore been proposed to employ apparatus for this purpose wherein the penicill n or other medical substance is atomized by a jet of oxygen and wherein the patient by the operation of a valve or vent limits the actual atomization to the period of inhalation so that the medicine is not wasted during exhalation. While this prior apparatus is useful, it is necessary for the patient to manipulate the control valve or vent. .This places a considerable burden upon a patient even though he may be able to do so, and many patients are wholly unable to perform this operation. 7
The object of the present invention is to provide apparatus of the type above referred to wherein a l quid medicament is atomized by a jet of compressed gas, for example oxygen, and having provision for the automatic limitation of the atomizing action to the period of inhalation, thus relieving the patient of the necessity of manipulating any control devices, and at the same time avoiding any waste of the expensive medicine. Another object of the invention is to provide simple atomizing apparatus for the intended purpose and such as may be manufactured at a reasonable cost so as to make it generally available. Other and further objects and advantages of the invention will be pointed out i in the following more detailed description and by reference to the accompanying drawings wherein Fig. 1 is a diagrammatic elevation illustrating the novel apparatus;
Fig. 2 is an edge elevation, partly broken away and to larger scale, showing details of the control mechanism with the parts in the position which they occupy during inhalation; and
Fig. 3 is a view similar to Fig. 2 but showing the position of the parts during exhalation.
Referring to the drawings, the numeral designates a casing of any suitable material, for instance a moulded plastic, glass or metal, delining a chamber 2, the lower part of which, in
the simple construction herein illustrated, constitutes a reservoir for a body 3 of the medicinal substance which is to be administered. The casing l is provided with a tubular branch 4 defining the delivery passage 5. This branch 4 may be shaped to be held in the mouth of the patient or alternatively it may be shaped tofit into one nostril or into both nostrils. The casing also has the tubular branch 6 providing the breathing port I, this port being of a size sufli'; cient to admit the passage of air in sufiicient quantity for breathing.
Within the chamber 2 there is arranged a jet nozzle 8 which is supplied with the medicinal substance from the body 3 by means of an elevat ng tube 9 supported by a rigid bracket It). The upper end of the elevating tube is so arranged, relatively to the jet nozzle 8, that the aspirating effect of gas delivered from the jet nozzle lifts the medicinal substance to the nozzle tip so that the medicinal substance is atomized by the jet of gas issuing from the nozzle. The
pressure motor l6 comprising a case I! which houses a very light and flexible diaphragm Hi. The case defines a chamber l9, at one side of the diaphragm, which communicates by means of a tube 2E3 with the chamber 2 of the casing I. Since the chamber I9 of the pressure motor communicates with the chamber 2 of the casing i the diaphragm is responsive to pressure variations in the chamber 2. The right-hand side of the diaphragm is open to atmospheric pressure at all times.
The support I5 is provided with a discharge port/2! which is controlled by a movable valve head 22. As illustrated, this valve head is carried by a lever 23 having an arm 23 which engages the central part of the diaphragm It; so that motion of the diaphragm causes the valve 22 to be seated or unseated.
Assuming that gas under pressure is being supplied through the tube I4 to the tubular support l5 and is thus available for delivery to the jet nozzle 8, if the patient places the part 4 in his mouth and inhales, the pressure in chamber 2 is slightly reduced, and this reduction in pressure is communicated to the chamber I9, thus the liquid to the nozzle tip in response to the aspirating action of the issuing gas jet, valve means including a movable valve head operative alternatively to deliver gas to the nozzle or to vent the gas to the atmosphere and a pressure motor including a movable diaphragm which moves in one direction in response to exhalation pressure and in the other direction in response to inhalation pressure, and means so connecting the diaphragm and valve head that the valve head is actuated to vent the gas to the atmosphere, thereby to cease vaporization during periods of exhalation.
9. Apparatus for use in administering a medicinal substance in atomized form for inhalation by a patient, said apparatus comprising a vaporizing nozzle, and having provision, includ ing a constantly open, unobstructed conduit for supplying gas under pressure to said nozzle, said conduit having a vent port intermediate its ends, and a movable valve head operative at times to close said port, and automatic means responsive to exhalation pressure to open said valve thereby to vent the gas to the atmosphere at a point intermediate the ends of the conduit.
10. Apparatus for use in administering a medicinal substance in atomized form, comprising means defining a chamber through which the patient inhales and exhales, the chamber having a constantly open aperture in its Wall of a size sufficient to pass air in the amount requisite for breathing, but such that the pressure in the chamber decreases and increases slightly in response to inhalation and exhalation respectively, a nozzle arranged to discharge the atomized medicinal substance into the chamber, a constantly open unobstructed conduit for leading gas under pressure from the source of supply to the nozzle, and means responsive to exhalation pressure Within the chamber to vent the gas on its way from the supply to the nozzle to the outer atmosphere.
JOHN H. EMERSON.
REFERENCES CITED The following references are of record in the file of this patent:
UNITED STATES PATENTS Number Name Date 2,181,421 Fahr et a1. Nov. 28%, 1939 FOREIGN PATENTS Number Country Date 500,789 Great Britain Feb. 15 1939
US68758646 1946-08-01 1946-08-01 Aspirator for administering medicine Expired - Lifetime US2535844A (en)

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Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2605764A (en) * 1948-01-23 1952-08-05 Frank H Adams Apparatus for nebulizing
US2693178A (en) * 1949-12-21 1954-11-02 Air Reduction Demand type gas regulator
US3083707A (en) * 1956-02-13 1963-04-02 Henry W Seeler Device for treatment of pulmonary diseases
US3362404A (en) * 1964-11-16 1968-01-09 Bennett Respiration Products I Respiration apparatus for administering intermittent positive pressure breathing therapy
DE1287260B (en) * 1962-08-31 1969-01-16 Merck & Co Inc Spray device
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US3777742A (en) * 1972-09-18 1973-12-11 Barber Colman Co Tantalum insufflator
US4396015A (en) * 1980-12-22 1983-08-02 Johnson Robert J Medication control device for use in treating lungs
EP0166476A2 (en) * 1984-05-28 1986-01-02 MALLINCKRODT, INC.(a Missouri corporation) Aerosol generator-inhalator
WO1997029799A2 (en) * 1996-02-13 1997-08-21 Trudell Medical Limited Nebulizer apparatus and method
US5666945A (en) * 1995-06-07 1997-09-16 Salter Labs Pneumatically-operated gas demand apparatus
FR2751883A1 (en) * 1996-08-01 1998-02-06 Cieutat Bertrand Pneumatic aerosol generator control unit, especially for medication nebuliser
EP0855224A3 (en) * 1997-01-27 1999-07-07 Medic-Aid Limited Atomizer
US6044841A (en) * 1997-08-29 2000-04-04 1263152 Ontario Inc. Breath actuated nebulizer with valve assembly having a relief piston
US20020157663A1 (en) * 2001-03-20 2002-10-31 Rick Blacker Nebulizer apparatus and method
US20030051729A1 (en) * 2001-09-16 2003-03-20 Eliezer Be'eri Inexsufflator
US20030136399A1 (en) * 2001-12-21 2003-07-24 Foley Martin P. Nebulizer apparatus and method
AU771684B2 (en) * 1996-02-13 2004-04-01 Trudell Medical International Nebulizer apparatus and method
US20070062519A1 (en) * 2004-02-24 2007-03-22 Boehringer Ingelheim International Gmbh Nebulizer
US7267120B2 (en) 2002-08-19 2007-09-11 Allegiance Corporation Small volume nebulizer
US7270123B2 (en) 2003-08-13 2007-09-18 Trudell Medical International Nebulizer apparatus and method
USRE40591E1 (en) 1994-11-11 2008-12-02 Profile Respiratory Systems Limited Atomizer
US20090199855A1 (en) * 2004-11-01 2009-08-13 Davenport James M System and method for conserving oxygen delivery while maintaining saturation
US7686036B1 (en) * 2008-10-13 2010-03-30 Youngdo Ind. Co., Ltd. Valve apparatus for movable oxygen cylinder
US8074642B2 (en) 2002-05-21 2011-12-13 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US8459252B2 (en) 2002-05-02 2013-06-11 Pari Innovative Manufacturers, Inc. Aerosol medication inhalation system
US20130277443A1 (en) * 2010-10-20 2013-10-24 Wolfe Tory Medical, Inc. Miniature fluid atomizer
USRE45068E1 (en) 2000-04-11 2014-08-12 Trudell Medical International Aerosol delivery apparatus
US9539408B2 (en) 2012-10-31 2017-01-10 Trudell Medical International Nebulizer apparatus
US20180001038A1 (en) * 2014-02-21 2018-01-04 Neogen Corporation Fluid Atomizer, Nozzle Assembly and Methods for Assembling and Utilizing the Same
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
US10850050B2 (en) 2016-05-19 2020-12-01 Trudell Medical International Smart valved holding chamber
EP3551261B1 (en) * 2016-12-09 2022-05-11 Trudell Medical International Smart nebulizer
US11666801B2 (en) 2018-01-04 2023-06-06 Trudell Medical International Smart oscillating positive expiratory pressure device
US11712175B2 (en) 2019-08-27 2023-08-01 Trudell Medical International Smart oscillating positive expiratory pressure device with feedback indicia
US11839716B2 (en) 2016-07-08 2023-12-12 Trudell Medical International Smart oscillating positive expiratory pressure device
US11964185B2 (en) 2023-04-24 2024-04-23 Trudell Medical International Smart oscillating positive expiratory pressure device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB500789A (en) * 1938-09-07 1939-02-15 Henry William Carsberg Improvements in and relating to apparatus for administering anaesthetic gases or vapours
US2181421A (en) * 1937-11-06 1939-11-28 George E Fahr Vaporizer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2181421A (en) * 1937-11-06 1939-11-28 George E Fahr Vaporizer
GB500789A (en) * 1938-09-07 1939-02-15 Henry William Carsberg Improvements in and relating to apparatus for administering anaesthetic gases or vapours

Cited By (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2605764A (en) * 1948-01-23 1952-08-05 Frank H Adams Apparatus for nebulizing
US2693178A (en) * 1949-12-21 1954-11-02 Air Reduction Demand type gas regulator
US3083707A (en) * 1956-02-13 1963-04-02 Henry W Seeler Device for treatment of pulmonary diseases
DE1287260B (en) * 1962-08-31 1969-01-16 Merck & Co Inc Spray device
US3362404A (en) * 1964-11-16 1968-01-09 Bennett Respiration Products I Respiration apparatus for administering intermittent positive pressure breathing therapy
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
US3777742A (en) * 1972-09-18 1973-12-11 Barber Colman Co Tantalum insufflator
US4396015A (en) * 1980-12-22 1983-08-02 Johnson Robert J Medication control device for use in treating lungs
EP0166476A2 (en) * 1984-05-28 1986-01-02 MALLINCKRODT, INC.(a Missouri corporation) Aerosol generator-inhalator
EP0166476A3 (en) * 1984-05-28 1986-04-02 Mallinckrodt, Inc. Aerosol generator-inhalator
USRE40591E1 (en) 1994-11-11 2008-12-02 Profile Respiratory Systems Limited Atomizer
US5666945A (en) * 1995-06-07 1997-09-16 Salter Labs Pneumatically-operated gas demand apparatus
US8061352B2 (en) 1996-02-13 2011-11-22 Trudell Medical International Aerosol delivery apparatus and method
WO1997029799A3 (en) * 1996-02-13 1997-10-23 Trudell Medical Ltd Nebulizer apparatus and method
US5823179A (en) * 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
US20040173209A1 (en) * 1996-02-13 2004-09-09 Trudell Medical International. Nebulizer apparatus and method
US6644304B2 (en) 1996-02-13 2003-11-11 1263152 Ontario Inc. Nebulizer apparatus and method
US6748945B2 (en) 1996-02-13 2004-06-15 Trudell Medical International Nebulizer apparatus and method
AU771684B2 (en) * 1996-02-13 2004-04-01 Trudell Medical International Nebulizer apparatus and method
AU734111B2 (en) * 1996-02-13 2001-06-07 Trudell Medical International Nebulizer apparatus and method
US7634995B2 (en) 1996-02-13 2009-12-22 Trudell Medical International Nebulizer apparatus and method
US7080643B2 (en) 1996-02-13 2006-07-25 Trudell Medical Internationl Nebulizer apparatus and method
WO1997029799A2 (en) * 1996-02-13 1997-08-21 Trudell Medical Limited Nebulizer apparatus and method
EP2324876A3 (en) * 1996-02-13 2012-08-22 Trudell Medical Limited Nebulizer apparatus and method
US6612303B1 (en) 1996-02-13 2003-09-02 1263152 Ontario Inc. Nebulizer apparatus and method
FR2751883A1 (en) * 1996-08-01 1998-02-06 Cieutat Bertrand Pneumatic aerosol generator control unit, especially for medication nebuliser
GB2321419B (en) * 1997-01-27 2001-02-07 Medic Aid Ltd Atomizer
US6129080A (en) * 1997-01-27 2000-10-10 Medic-Aid Limited Atomizer
EP0855224A3 (en) * 1997-01-27 1999-07-07 Medic-Aid Limited Atomizer
US6450163B1 (en) 1997-08-29 2002-09-17 Trudell Medical International Breath actuated nebulizer with valve assembly having a relief piston
US6044841A (en) * 1997-08-29 2000-04-04 1263152 Ontario Inc. Breath actuated nebulizer with valve assembly having a relief piston
USRE46050E1 (en) 2000-04-11 2016-07-05 Trudell Medical International Aerosol delivery apparatus
USRE45068E1 (en) 2000-04-11 2014-08-12 Trudell Medical International Aerosol delivery apparatus
US20050205085A1 (en) * 2001-03-20 2005-09-22 Trudell Medical International Nebulizer apparatus and method
US6929003B2 (en) 2001-03-20 2005-08-16 Trudell Medical International Nebulizer apparatus and method
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US9907918B2 (en) 2001-03-20 2018-03-06 Trudell Medical International Nebulizer apparatus and method
US20020157663A1 (en) * 2001-03-20 2002-10-31 Rick Blacker Nebulizer apparatus and method
US7905228B2 (en) 2001-03-20 2011-03-15 Trudell Medical International Nebulizer apparatus and method
US7096866B2 (en) * 2001-09-16 2006-08-29 Alyn Woldenberg Family Hospital Inexsufflator
US20030051729A1 (en) * 2001-09-16 2003-03-20 Eliezer Be'eri Inexsufflator
US7559322B2 (en) 2001-12-21 2009-07-14 Trudell Medical International Nebulizer apparatus and method
US8397712B2 (en) 2001-12-21 2013-03-19 Trudell Medical International Nebulizer apparatus and method
US6994083B2 (en) 2001-12-21 2006-02-07 Trudell Medical International Nebulizer apparatus and method
US20030136399A1 (en) * 2001-12-21 2003-07-24 Foley Martin P. Nebulizer apparatus and method
US8844520B2 (en) 2001-12-21 2014-09-30 Trudell Medical International Nebulizer apparatus and method
US7568480B2 (en) 2001-12-21 2009-08-04 Trudell Medical International Nebulizer apparatus and method
US9308335B2 (en) 2002-05-02 2016-04-12 Pre Holding, Inc. Aerosol medication inhalation system
US8459252B2 (en) 2002-05-02 2013-06-11 Pari Innovative Manufacturers, Inc. Aerosol medication inhalation system
US8973571B1 (en) 2002-05-02 2015-03-10 Pre Holding, Inc. Aerosol medication inhalation system
US9814849B2 (en) 2002-05-21 2017-11-14 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
US8074642B2 (en) 2002-05-21 2011-12-13 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US8550067B2 (en) 2002-05-21 2013-10-08 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US9700689B2 (en) 2002-05-21 2017-07-11 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
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US7267120B2 (en) 2002-08-19 2007-09-11 Allegiance Corporation Small volume nebulizer
US7270123B2 (en) 2003-08-13 2007-09-18 Trudell Medical International Nebulizer apparatus and method
US7954487B2 (en) 2003-08-13 2011-06-07 Trudell Medical International Nebulizer apparatus and method
US20070062519A1 (en) * 2004-02-24 2007-03-22 Boehringer Ingelheim International Gmbh Nebulizer
US7571722B2 (en) 2004-02-24 2009-08-11 Boehringer Ingelheim International Gmbh Nebulizer
US20090199855A1 (en) * 2004-11-01 2009-08-13 Davenport James M System and method for conserving oxygen delivery while maintaining saturation
US20100089400A1 (en) * 2008-10-13 2010-04-15 Kwang Ho Lee Valve apparatus for movable oxygen cylinder
US7686036B1 (en) * 2008-10-13 2010-03-30 Youngdo Ind. Co., Ltd. Valve apparatus for movable oxygen cylinder
US20130277443A1 (en) * 2010-10-20 2013-10-24 Wolfe Tory Medical, Inc. Miniature fluid atomizer
US9539408B2 (en) 2012-10-31 2017-01-10 Trudell Medical International Nebulizer apparatus
US10668229B2 (en) 2012-10-31 2020-06-02 Trude Medical International Nebulizer apparatus
US20180001038A1 (en) * 2014-02-21 2018-01-04 Neogen Corporation Fluid Atomizer, Nozzle Assembly and Methods for Assembling and Utilizing the Same
US10850050B2 (en) 2016-05-19 2020-12-01 Trudell Medical International Smart valved holding chamber
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
US11839716B2 (en) 2016-07-08 2023-12-12 Trudell Medical International Smart oscillating positive expiratory pressure device
EP3551261B1 (en) * 2016-12-09 2022-05-11 Trudell Medical International Smart nebulizer
US11497867B2 (en) 2016-12-09 2022-11-15 Trudell Medical International Smart nebulizer
US11666801B2 (en) 2018-01-04 2023-06-06 Trudell Medical International Smart oscillating positive expiratory pressure device
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