US2814575A - Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration - Google Patents
Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration Download PDFInfo
- Publication number
- US2814575A US2814575A US449613A US44961354A US2814575A US 2814575 A US2814575 A US 2814575A US 449613 A US449613 A US 449613A US 44961354 A US44961354 A US 44961354A US 2814575 A US2814575 A US 2814575A
- Authority
- US
- United States
- Prior art keywords
- ampoules
- cleaning
- ampoule
- liquid
- bath
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
- B08B3/12—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration by sonic or ultrasonic vibrations
- B08B3/123—Cleaning travelling work, e.g. webs, articles on a conveyor
- B08B3/126—Cleaning travelling work, e.g. webs, articles on a conveyor in particular moving bottles
Definitions
- This invention relates generally to the cleaning of vessels or containers, and more specifically concerns an improved method and apparatus for removing foreign matter from within glass ampoules intended to be used for accommodating sterile drugs and similar materials.
- the cleaning of ampoules usually involves the use of a variety of cleaning agents and detergents dissolved in water or other suitable carrier and forcibly injected into each ampoule. While these porcedures have been found to remove a large part of the foreign matter and produce an acceptable product for packaging drugs, they have not been entirely satisfactory as even the most vigorous cleaning methods will not remove the extremely minute particles that either cling to the walls of the ampoule or are partially imbedded in the microscopically small crevices or interstices therein. It is an object of the present invention to effect the removal of these minute particles through the use of vibration generating means wherein high frequency vibrations are imparted to and introduced into the walls of the ampoule duirng the Cleaning process.
- Another object of the invention is to provide a new and improved method and apparatus that is readily adaptable to automatic and semi-automatic ampoule cleaning equipment, and which will not only expedite the cleaning process but will enable substantial simplification of the apparatus and procedures normally required.
- Still another object of the invention resides in the provision of an improved device readily applicable to antomatic ampoule cleaning apparatus, well adapted to effect more thorough and rapid cleaning, and characterized by its structural and operational simplicity and relatively low cost.
- Figure 1 is an elevational view of ampoule cleaning apparatus embodying the features of the invention
- Figure 2 is a cross-sectional view of Figure 1 taken along the line 22 thereof;
- Figure 3 is a diagrammatic cross-sectional view of the vibration generating means and associated energizing equipment.
- a plurality of ampoules 10 having narrowed neck parts 11 are arranged to be carried or transported by a moving belt 13 by engagement with a plurality of spaced notches 14.
- the ampoules hang from the belt, open ends upward. While only fragments of the lower and upper laps of this belt 13 are shown in the figures, it is understood that it is a continuous endless belt supported at its ends by suitable supporting and rotating equipment.
- the upper lap of the belt is supported during its travel by a longitudinal guide 15 rested within an L-shaped member 16 supported by a horizontal bracket 17.
- the bracket 17 is secured to the upper end of a cylindrical support member 18 mounted on the base 18'.
- the ampoules are retained within the belt slots 14 by a front guide 19 supported on a longitudinal T-shaped member 20.
- the ampoules 10 are preferably processed in groups of two or more.
- the belt 13 is moved intermittently (by belt advancing means of any suitable character, not shown) to transport these groups to successive processing stations of which only one (a cleaning station) is illustrated.
- the ampoules 10 are shown as being processed in groups of twelve, and the cleaning head 22 is therefore provided with a group of twelve nozzles 23.
- the head is positioned above the belt 13 and the injection nozzles 23 extend downwardly therefrom.
- Each of the nozzles 23 is provided with a tubular body part 24 disposed within the head 22 and having an opening 25 communicating with a longitudinal manifold 26.
- the cleaning liquid such as water with or without a suitable detergent
- the cleaning liquid is injected into the manifold 26 by means of an inlet hose 27 whereupon it then passes through the openings 25 in the nozzle body parts 24 and thence through and out of the lower ends of the several nozzles. This action occurs each time the nozzles are moved to the lowered position shown in dotted outline in Figure 2.
- These cavities are coupled with a longitudinal opening or exhaust manifold 28 which is in turn connected to an exhaust tube 29. In this way the cleaning liquid is forcibly introduced into and withdrawn from each ampoule and effectively removes all loose foreign matter.
- the head assembly 22 is reciprocably mounted by means of a collar 32 secured to the upper end of a shaft 33.
- This shaft is slideably mounted within the cylindrical column 18.
- the lower end of the shaft 33 carries a cam follower wheel 34 which rides on a cam 35 secured to a central or main cam shaft 36.
- Rotation of the shaft 36 in synchronism with the intermittent movement of the belt 13 will cause the head 22 together with the nozzles 23 to be moved downwardly each time the belt 13 stops and to permit water to be injected into and withdraws from each capsule or group of ampoules coming to rest beneath the head.
- the cam raises the head 22 whereupon the belt 13 is operated to remove one group of ampoules and bring a succeeding group to the washing station.
- a liquid container 37 reciprocably mounted on the upper end of shaft 38 carried within a vertical guide 39 supported on the base 18.
- the bottom end of the rod 38 carries a cam follower 40 which rides on the periphcry of a cam 41 on and rotated by the shaft 36.
- the earns 41 and 35 are so arranged and coordinated that the cam 35 rotates to lower the head 22 the cam 41 will simultaneously raise the liquid container 37 to submerge the lower parts of the ampoules. This submergence is indicated in dotted lines in Figure 2.
- the cam 41 will function to move the container 37 downwardly, thus freeing the ampoules so that the belt can displace them relative to the cleaning station.
- the generation of pressure waves to expedite and effect more complete cleaning of the ampoules is accomplished by an elongated transducer 42 disposed in the container 37.
- This transducer is preferably curved about a longitudinal axis so that it will tend to direct the pressure waves generated by vibration of the top side of the transducer toward the bottom of the ampoules 10 and thus improve the transfer of energy to the ampoules.
- a ceramic plate respons ive to alternating current frequencies in the desired range may be used.
- a ceramic plate may comprise barium or strontium titanate or a mixture thereof or it may comprise any other suitable magnetostrictive substance such as lead zirconate.
- metal electrodes 44- and 45 of aluminum, silver or other suitable material having a low conductivity are plated or otherwise secured to each side of the plate 43 as shown in Figure 3.
- the oscillator 43 may be of any conventional structure suitable for generating alternating current frequencies in the range of 20 kc. to 500 kc. and functions to cause the transducing element 43 to enlarge and contract in synchronism with the alternations of the applied energy.
- a suitable insulating material 51 of plastic, glass .or the like that will present very little impedance to the transmission of energy from the ceramic plate 43 to the liquid bath 37.
- the transducer may be supported within the bath 37 by any suitable means that will hold it in position and in the desired alignment with the ampoules to be cleaned.
- pressure waves generated by the transducer 42 are transmitted by means of the water or other liquid 37 to the ampoules it) and cause them to be set into vibration. Some of this energy passes through the walls and into the cleaning fluid within the ampoules 19; some of it functions to set into motion the inner wall surface of each ampoule immersed in the bath. These various vibrations combine to release minute impurity particles, and .this enables them to be carried out of the ampoule by the cleaning fluid injected into it.
- Apparatus for cleaning glass ampoules comprising means for supporting an ampoule, means for injecting a liquid into and withdrawing it from said ampoule, a bath of another liquid having vibration generating means therein, and means for submerging at least part of said ampoule into said bath during the injection and withdrawal of the first-named liquid.
- Apparatus for cleaning glass ampoules comprising means for supporting an ampoule to be cleaned, a liquid bath, electrically actuated vibration generating means in said bath for imparting pressure waves thereto, means for submerging said ampoule in said bath, and means for injecting another liquid into and withdrawing it from said ampoule during immersion thereof in said bath.
- Apparatus for cleaning ampoules comprising a conveyor belt for transporting ampoules to be cleaned, a cleaning head including at least one liquid injection nozzle, means for moving said nozzle into and out of successive ampoules, a liquid bath disposed beneath said belt and movable toward and away from the belt for submergence of said ampoules, and means for generating ultrasonic pressure waves in said bath.
- Apparatus according to claim 4 wherein the lastrnentioned means includes an ultrasonic transducer curved about its longitudinal axis and positioned within said bath, the radii of curvature converging toward the submerged ampoules.
- Apparatus for cleaning ampoules comprising a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules hanging from said belt with their open ends upward, a group of injection nozzles mounted for .reciprocable movement relative to said belt for injection of cleaning liquid into successive groups of ampoules, means for reciprocating said nozzles, means operatively connected with said nozzles for withdrawing the injected liquid, a reciprocably mounted bath below said ampoules for submerging at least part of each ampoule during injection of liquid therein, means for reciprocating said bath and ultrasonic generating means in said bath for vibrating the walls of said ampoules to release minute particles of foreign matter and facilitate their removal by said injected liquid.
- the method of cleaning ampoules comprising the steps of injecting a cleaning liquid into and removing it from an ampoule being cleaned, and simultaneously subjecting said ampoule to ultrasonic pressure waves 8.
- the method of cleaning ampoules comprising the steps of immersing an ampoule to be cleaned in a bath with its ,open end extending upwardly from the surface of said bath, generating ultrasonic pressure waves in said bath, and simultaneously injecting a cleaning fluid into and removing it from said ampoule.
- an ampoule cleaning procedure the steps which involve intermittently advancing a train of ampoules open end upward to and past a cleaning station so that at least one ampoule is at rest at said station between periods of advancement, providing at said station a liquid bath in which ultrasonic vibrations are imparted to the liquid, submerging in said bath the ampoule or ampoules coming to rest at said station, and flushing the interior of each such ampoule with a cleaning liquid during the period of its immersion in said bath.
- a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules being carried by said belt with their open ends upward, cleaning liquid injection and withdrawing mechanism above said belt, including injection nozzles adapted to enter said ampoules, means for elfecting relative movement between said mechanism and said ampoules so that cleaning liquid may be injected into and Withdrawn from successive groups of ampoules, a liquid bath below said belt, means for eifecting relative movement between said bath and said ampoules so as to submerge at least part of each arnpoule in said bath during injection of cleaning liquid into it, and ultrasonic generating means in said bath for vibrating the Walls of the sub merged ampoules to release minute particles of foreign matter and facilitate their removal by said cleaning liquid.
- a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules being carried by said belt with their open ends upward, cleaning liquid injection and withdrawing mechanism above said belt, including injection nozzles adapted to enter said ampoules, means for moving said mechanism up and down so that cleaning liquid may be injected into and withdrawn from successive groups of ampoules, a liquid bath below said belt, means for mov ing said bath up and down in timed relation to the move ments of said cleaning liquid mechanism so as to submerge at least part of each ampoule in said bath during injection of cleaning liquid into it, and ultrasonic generating means in said bath for vibrating the walls of the submerged ampoules to release minute particles of foreign matter and facilitate their removal by said cleaning liquid.
Description
Nov. 26, 1957 R. LANGE. JR 2,814,575
METHOD AND APPARATUS FOR CLEANING AMPOULES WITH THE AID OF ULTRASONIC VIBRATION Filed Aug. 15, 1954 Ll-z INVENTQR lizlcfidroi Z007 OSCILLATOR 2,8M,575 Patented Nov. 26, 1957 METHOD APPARATUS FOR CLEANING AMIPOULES WITH THE All) F ULTRA- SGNIC VIBRATION Richard Lange, Jr., Westwood, N. 3., assignor to Hades Lange orporation, North Bergen, N. J., a corporation of N ew Jersey Application August 13, 1954, Serial No. 449,613
12 Claims. (6]. 134-1) This invention relates generally to the cleaning of vessels or containers, and more specifically concerns an improved method and apparatus for removing foreign matter from within glass ampoules intended to be used for accommodating sterile drugs and similar materials.
The cleaning of ampoules usually involves the use of a variety of cleaning agents and detergents dissolved in water or other suitable carrier and forcibly injected into each ampoule. While these porcedures have been found to remove a large part of the foreign matter and produce an acceptable product for packaging drugs, they have not been entirely satisfactory as even the most vigorous cleaning methods will not remove the extremely minute particles that either cling to the walls of the ampoule or are partially imbedded in the microscopically small crevices or interstices therein. It is an object of the present invention to effect the removal of these minute particles through the use of vibration generating means wherein high frequency vibrations are imparted to and introduced into the walls of the ampoule duirng the Cleaning process.
Another object of the invention is to provide a new and improved method and apparatus that is readily adaptable to automatic and semi-automatic ampoule cleaning equipment, and which will not only expedite the cleaning process but will enable substantial simplification of the apparatus and procedures normally required.
Still another object of the invention resides in the provision of an improved device readily applicable to antomatic ampoule cleaning apparatus, well adapted to effect more thorough and rapid cleaning, and characterized by its structural and operational simplicity and relatively low cost.
The above and other objects and advantages of the invention will become more apparent from the following description and accompanying drawings forming part of this application.
In the drawings:
Figure 1 is an elevational view of ampoule cleaning apparatus embodying the features of the invention;
Figure 2 is a cross-sectional view of Figure 1 taken along the line 22 thereof; and
Figure 3 is a diagrammatic cross-sectional view of the vibration generating means and associated energizing equipment.
As pointed out above the cleaning of ampoules has heretofore been carried out by the injection of Water or other liquid under pressure into each ampoule in a manner that mechanically flushes out particles of foreign matter. While this procedure is generally satisfactory it does not effectively remove the minuter particles which, while inactivated by subsequent sterilizing processes, still remain within the ampoule and become intermixed with the fluid or other material ultimately to be held therein.
It has been found that these minute and even micro scopic particles of foreign matter can be removed from within the ampoule by subjecting the cleaning fluid injected into the ampoule to high frequency pressure waves which function to vibrate the ampoule wall and cause these minute particles to become dislodged and carried away with the cleaning liquid. Through the utilization of frequencies exceeding 20 kilocycles and preferably of the order of 400 to 500 kilocycles it has been found that highly effective and efiicient cleaning action can be attained. This is brought about by reason of the differences in the physical characteristics of the ampoule wall and the particles adhered thereto which causes the particles to oscillate at periods of vibration different from those of the wall. With the particles and the ampoule wall oscillating in different ways the force tending to cause the particles to adhere to the wall is overcome with the result that the particles are shaken loose and fall away and are carried off by the washing or cleaning fluid.
One embodiment of the invention for the attainment of these ends is illustrated in the drawing and is intended to be illustrative rather than restrictive of the invention. In this form, a plurality of ampoules 10 having narrowed neck parts 11 are arranged to be carried or transported by a moving belt 13 by engagement with a plurality of spaced notches 14. The ampoules hang from the belt, open ends upward. While only fragments of the lower and upper laps of this belt 13 are shown in the figures, it is understood that it is a continuous endless belt supported at its ends by suitable supporting and rotating equipment.
The upper lap of the belt is supported during its travel by a longitudinal guide 15 rested within an L-shaped member 16 supported by a horizontal bracket 17. The bracket 17 is secured to the upper end of a cylindrical support member 18 mounted on the base 18'. The ampoules are retained within the belt slots 14 by a front guide 19 supported on a longitudinal T-shaped member 20.
In order to expedite the cleaning process, the ampoules 10 are preferably processed in groups of two or more. The belt 13 is moved intermittently (by belt advancing means of any suitable character, not shown) to transport these groups to successive processing stations of which only one (a cleaning station) is illustrated. For present purposes the ampoules 10 are shown as being processed in groups of twelve, and the cleaning head 22 is therefore provided with a group of twelve nozzles 23. The head is positioned above the belt 13 and the injection nozzles 23 extend downwardly therefrom. Each of the nozzles 23 is provided with a tubular body part 24 disposed within the head 22 and having an opening 25 communicating with a longitudinal manifold 26. The cleaning liquid, such as water with or without a suitable detergent, is injected into the manifold 26 by means of an inlet hose 27 whereupon it then passes through the openings 25 in the nozzle body parts 24 and thence through and out of the lower ends of the several nozzles. This action occurs each time the nozzles are moved to the lowered position shown in dotted outline in Figure 2. As the water or liquid is injected into each ampoule it is simultaneously withdrawn by means of a series of cavities 30 surrounding the nozzles and engaging the open ends 31 of respective ampoules when the head 22 is lowered. These cavities are coupled with a longitudinal opening or exhaust manifold 28 which is in turn connected to an exhaust tube 29. In this way the cleaning liquid is forcibly introduced into and withdrawn from each ampoule and effectively removes all loose foreign matter.
The head assembly 22 is reciprocably mounted by means of a collar 32 secured to the upper end of a shaft 33. This shaft is slideably mounted within the cylindrical column 18. The lower end of the shaft 33 carries a cam follower wheel 34 which rides on a cam 35 secured to a central or main cam shaft 36. Rotation of the shaft 36 in synchronism with the intermittent movement of the belt 13 (by any suitable means, not shown) will cause the head 22 together with the nozzles 23 to be moved downwardly each time the belt 13 stops and to permit water to be injected into and withdraws from each capsule or group of ampoules coming to rest beneath the head. After a given time the cam raises the head 22 whereupon the belt 13 is operated to remove one group of ampoules and bring a succeeding group to the washing station.
Beneath the upper lap of the belt 13 and in line therewith is a liquid container 37 reciprocably mounted on the upper end of shaft 38 carried within a vertical guide 39 supported on the base 18. The bottom end of the rod 38 carries a cam follower 40 which rides on the periphcry of a cam 41 on and rotated by the shaft 36. The earns 41 and 35 are so arranged and coordinated that the cam 35 rotates to lower the head 22 the cam 41 will simultaneously raise the liquid container 37 to submerge the lower parts of the ampoules. This submergence is indicated in dotted lines in Figure 2. Similarly when the head 22 is moved upwardly (full lines, Figure 2) the cam 41 will function to move the container 37 downwardly, thus freeing the ampoules so that the belt can displace them relative to the cleaning station.
The generation of pressure waves to expedite and effect more complete cleaning of the ampoules is accomplished by an elongated transducer 42 disposed in the container 37. This transducer is preferably curved about a longitudinal axis so that it will tend to direct the pressure waves generated by vibration of the top side of the transducer toward the bottom of the ampoules 10 and thus improve the transfer of energy to the ampoules.
While any suitable transducer may be employed that is capable of generating pressure waves within the liquid 3'7 and more particularly pressure waves of a frequency in the range of 20 kc. to 500 lcc., a ceramic plate respons ive to alternating current frequencies in the desired range may be used. Such a ceramic plate may comprise barium or strontium titanate or a mixture thereof or it may comprise any other suitable magnetostrictive substance such as lead zirconate. In order to set the plate 43 into oscillation, metal electrodes 44- and 45 of aluminum, silver or other suitable material having a low conductivity are plated or otherwise secured to each side of the plate 43 as shown in Figure 3. These electrodes are connected through suitable insulated wires 46 and 47 to an oscillater or high frequency generator 48 connected to a source of power by means of terminals 49 and 50. The oscillator 43 may be of any conventional structure suitable for generating alternating current frequencies in the range of 20 kc. to 500 kc. and functions to cause the transducing element 43 to enlarge and contract in synchronism with the alternations of the applied energy.
in order to prevent the electrodes {i l and 4-5 from being short-circuited by reason of the immersion of the transducer Within the fluid 37', it is preferably completely covered by a suitable insulating material 51 of plastic, glass .or the like that will present very little impedance to the transmission of energy from the ceramic plate 43 to the liquid bath 37.
The transducer may be supported within the bath 37 by any suitable means that will hold it in position and in the desired alignment with the ampoules to be cleaned.
In the operation of the device pressure waves generated by the transducer 42 are transmitted by means of the water or other liquid 37 to the ampoules it) and cause them to be set into vibration. Some of this energy passes through the walls and into the cleaning fluid within the ampoules 19; some of it functions to set into motion the inner wall surface of each ampoule immersed in the bath. These various vibrations combine to release minute impurity particles, and .this enables them to be carried out of the ampoule by the cleaning fluid injected into it.
With the apparatus described, it has been found that the use of ultrasonic vibrations not only aids in the removal of extremely minute particles of matter but also greatly assists in the removal of the larger particles. Tests have indicated that with prior apparatus the use of as much as 200 lbs. pressure in the injection of cleaning fluid for periods of 30 seconds or more failed to effect complete cleaning, while with the use of ultrasonic vibrations as herein described, more thorough cleaning was accomplished in as little as 5 seconds and with the use of only 5 cc. of cleaning liquid. Thus a substantial saving of time and equipment as well as cleaning materials is attained. Inasmuch as many drugs and particularly those in liquid form are packaged in so-called single dose quantities to avoid accidental contamination of larger quantities when packaged in bulk, these savings in time, maintenance and cost of equipment constitute a substantial reduction in the cost of the packaged article.
While only one embodiment of this invention has been illustrated and described, it is apparent that modifications, alterations and changes may be made without departing from the true scope and spirit thereof.
Having thus described my invention what I claim as new and desire to secure by Letters Patent is:
1. Apparatus for cleaning glass ampoules comprising means for supporting an ampoule, means for injecting a liquid into and withdrawing it from said ampoule, a bath of another liquid having vibration generating means therein, and means for submerging at least part of said ampoule into said bath during the injection and withdrawal of the first-named liquid.
2. Apparatus for cleaning glass ampoules comprising means for supporting an ampoule to be cleaned, a liquid bath, electrically actuated vibration generating means in said bath for imparting pressure waves thereto, means for submerging said ampoule in said bath, and means for injecting another liquid into and withdrawing it from said ampoule during immersion thereof in said bath.
3. Apparatus for cleaning ampoules according to claim 2 wherein said generating means is shaped to direct the pressure waves toward said ampoule.
4. Apparatus for cleaning ampoules comprising a conveyor belt for transporting ampoules to be cleaned, a cleaning head including at least one liquid injection nozzle, means for moving said nozzle into and out of successive ampoules, a liquid bath disposed beneath said belt and movable toward and away from the belt for submergence of said ampoules, and means for generating ultrasonic pressure waves in said bath.
5. Apparatus according to claim 4 wherein the lastrnentioned means includes an ultrasonic transducer curved about its longitudinal axis and positioned within said bath, the radii of curvature converging toward the submerged ampoules.
6. Apparatus for cleaning ampoules comprising a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules hanging from said belt with their open ends upward, a group of injection nozzles mounted for .reciprocable movement relative to said belt for injection of cleaning liquid into successive groups of ampoules, means for reciprocating said nozzles, means operatively connected with said nozzles for withdrawing the injected liquid, a reciprocably mounted bath below said ampoules for submerging at least part of each ampoule during injection of liquid therein, means for reciprocating said bath and ultrasonic generating means in said bath for vibrating the walls of said ampoules to release minute particles of foreign matter and facilitate their removal by said injected liquid.
7. The method of cleaning ampoules comprising the steps of injecting a cleaning liquid into and removing it from an ampoule being cleaned, and simultaneously subjecting said ampoule to ultrasonic pressure waves 8. The method of cleaning ampoules comprising the steps of immersing an ampoule to be cleaned in a bath with its ,open end extending upwardly from the surface of said bath, generating ultrasonic pressure waves in said bath, and simultaneously injecting a cleaning fluid into and removing it from said ampoule.
9. In an ampoule cleaning procedure, the steps which involve advancing an ampoule open end upward to a cleaning station, then at said station submerging the lower part of said ampoule in a liquid bath in which ultrasonic pressure waves are being generated, and flushing the interior of said ampoule with a cleaning liquid during said immersion thereof in said bath.
10. In an ampoule cleaning procedure, the steps which involve intermittently advancing a train of ampoules open end upward to and past a cleaning station so that at least one ampoule is at rest at said station between periods of advancement, providing at said station a liquid bath in which ultrasonic vibrations are imparted to the liquid, submerging in said bath the ampoule or ampoules coming to rest at said station, and flushing the interior of each such ampoule with a cleaning liquid during the period of its immersion in said bath.
11. In apparatus for cleaning ampoules, a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules being carried by said belt with their open ends upward, cleaning liquid injection and withdrawing mechanism above said belt, including injection nozzles adapted to enter said ampoules, means for elfecting relative movement between said mechanism and said ampoules so that cleaning liquid may be injected into and Withdrawn from successive groups of ampoules, a liquid bath below said belt, means for eifecting relative movement between said bath and said ampoules so as to submerge at least part of each arnpoule in said bath during injection of cleaning liquid into it, and ultrasonic generating means in said bath for vibrating the Walls of the sub merged ampoules to release minute particles of foreign matter and facilitate their removal by said cleaning liquid.
12. In apparatus for cleaning ampoules, a conveyor belt for transporting successive groups of ampoules to be cleaned, said ampoules being carried by said belt with their open ends upward, cleaning liquid injection and withdrawing mechanism above said belt, including injection nozzles adapted to enter said ampoules, means for moving said mechanism up and down so that cleaning liquid may be injected into and withdrawn from successive groups of ampoules, a liquid bath below said belt, means for mov ing said bath up and down in timed relation to the move ments of said cleaning liquid mechanism so as to submerge at least part of each ampoule in said bath during injection of cleaning liquid into it, and ultrasonic generating means in said bath for vibrating the walls of the submerged ampoules to release minute particles of foreign matter and facilitate their removal by said cleaning liquid.
References Cited in the file of this patent UNITED STATES PATENTS 1,139,313 Stevens May 11, 1915 1,445,359 Scarborough Feb. 13, 1923 2,102,819 Ronci Dec. 21, 1937 2,616,820 Bourgeaux Nov. 4, 1952
Claims (2)
1. APPARATUS FOR CLEANING GLASS AMPOULES COMPRISING MEANS FOR SUPPORTING AN AMPOULE, MEANS FOR INJECTING A LIQUID INTO AND WITHDRAWING IT FROM SAID AMPOULE, A BATH OF ANOTHER LIQUID HAVING VIBRATION GENERATING MEANS THEREIN, AND MEANS FOR SUBMERGING AT LEAST PART OF SAID AMPOULE INTO SAID BATH DURING THE INJECTION AND WITHDRAWAL OF THE FIRST-NAMED LIQUID.
7. THE METHOD OF CLEANING AMPOULES COMPRISING THE STEPS OF INJECTING A CLEANING LIQUID INTO AND REMOVING IT FROM AN AMPOULE BEING CLEANED, AND SIMULTANEOUSLY SUBJECTING SAID AMPOULE TO ULTRASONIC PRESSURE WAVES.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US449613A US2814575A (en) | 1954-08-13 | 1954-08-13 | Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US449613A US2814575A (en) | 1954-08-13 | 1954-08-13 | Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration |
Publications (1)
Publication Number | Publication Date |
---|---|
US2814575A true US2814575A (en) | 1957-11-26 |
Family
ID=23784815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US449613A Expired - Lifetime US2814575A (en) | 1954-08-13 | 1954-08-13 | Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration |
Country Status (1)
Country | Link |
---|---|
US (1) | US2814575A (en) |
Cited By (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2968584A (en) * | 1956-10-31 | 1961-01-17 | Corning Glass Works | Glass tube cleaning |
US2974070A (en) * | 1957-02-07 | 1961-03-07 | American Enka Corp | Process for cleaning spinnerets |
US2980123A (en) * | 1955-11-14 | 1961-04-18 | Jerome H Lemelson | Ultrasonic apparatus |
US2992142A (en) * | 1958-01-17 | 1961-07-11 | Detrex Chem Ind | Ultrasonic cleaning method |
US3022202A (en) * | 1956-04-09 | 1962-02-20 | Libbey Owens Ford Glass Co | Method of cleaning surfaces |
US3047434A (en) * | 1958-03-28 | 1962-07-31 | Bendix Corp | Solutions and methods for radioactive decontamination |
US3068829A (en) * | 1959-11-13 | 1962-12-18 | Carl W Nuissl | Device for cleaning vessels |
US3085185A (en) * | 1959-05-12 | 1963-04-09 | Detrex Chem Ind | Ultrasonic cleaning apparatus |
US3224213A (en) * | 1964-07-17 | 1965-12-21 | Jr Earl E Hoyt | Method for making and harvesting ice using ultrasonic vibrators |
US3233449A (en) * | 1960-10-06 | 1966-02-08 | Republic Steel Corp | Method and apparatus for ultrasonic testing of pipe |
US3253219A (en) * | 1961-06-01 | 1966-05-24 | Union Oil Co | Method using change of piezoelectric crystal frequency to determine corrosion rate and apparatus therefor |
US3291640A (en) * | 1963-05-27 | 1966-12-13 | Chemclean Corp | Ultrasonic cleaning process |
US3364067A (en) * | 1963-12-24 | 1968-01-16 | Gen Dynamics Corp | Method and apparatus for surface cleaning |
US3448743A (en) * | 1966-11-07 | 1969-06-10 | R & D Suppliers Inc | Apparatus for cleaning containers |
US3628873A (en) * | 1969-02-22 | 1971-12-21 | Leitz Ernst Gmbh | Method of continuously determining the degree of pollution of translucent liquids and apparatus therefor |
US4036168A (en) * | 1973-09-10 | 1977-07-19 | Omnitech Inc. | Apparatus for coating articles |
US4082565A (en) * | 1975-12-15 | 1978-04-04 | Rino Sjolander | Method and apparatus for the removal of deposits from a fuel injection valve |
US4091495A (en) * | 1976-05-17 | 1978-05-30 | Aspenlind Ake Lars G | Gas cylinder washing, draining and/or drying apparatus |
US4106155A (en) * | 1976-10-06 | 1978-08-15 | Cortex Research Corporation | Apparatus for washing contaminated laboratory containers |
US4211744A (en) * | 1978-05-24 | 1980-07-08 | Biophysics Research & Consulting Corporation | Process for ultrasonic pasteurization |
US4377880A (en) * | 1981-02-27 | 1983-03-29 | The United States Of America As Represented By The United States Department Of Energy | Cleaning method and apparatus |
US4525219A (en) * | 1983-04-11 | 1985-06-25 | Gard Corporation | Ampule cleaning and quality control system |
US4559664A (en) * | 1981-08-31 | 1985-12-24 | Prolic Ag | Automatic washing- and rinsing device for titration plates or the like |
US4565942A (en) * | 1983-07-01 | 1986-01-21 | Murata Manufacturing Co., Ltd. | Energy trapped piezoelectric resonator liquid sensor |
US4582077A (en) * | 1983-08-22 | 1986-04-15 | Skoda, Koncernovy Podnik | Arrangement for cleaning of objects by means of a close ultrasonic field |
US4607652A (en) * | 1984-08-29 | 1986-08-26 | Yung Simon K C | Contact lens cleaning apparatus |
US4697605A (en) * | 1984-08-29 | 1987-10-06 | Smc Metal Tech Co., Ltd. | Contact lens cleaning apparatus |
US4754186A (en) * | 1986-12-23 | 1988-06-28 | E. I. Du Pont De Nemours And Company | Drive network for an ultrasonic probe |
US5254900A (en) * | 1989-06-23 | 1993-10-19 | Siemens Aktiengesellschaft | Broad beam ultrasonic transducer |
US5355048A (en) * | 1993-07-21 | 1994-10-11 | Fsi International, Inc. | Megasonic transducer for cleaning substrate surfaces |
US5353823A (en) * | 1989-09-29 | 1994-10-11 | Starrfras Maschinen AG | Device for cleaning the fastening shank of a tool or of a toolholder |
US5534076A (en) * | 1994-10-03 | 1996-07-09 | Verteg, Inc. | Megasonic cleaning system |
EP0792699A2 (en) * | 1996-03-01 | 1997-09-03 | Pharma-Tech Co. Ltd. | Apparatus and process for ultrasonic cleaning |
US5713101A (en) * | 1995-12-13 | 1998-02-03 | Jackson; Robert L. | Nozzles and container cleaning system |
US6039059A (en) * | 1996-09-30 | 2000-03-21 | Verteq, Inc. | Wafer cleaning system |
US20030084535A1 (en) * | 2001-10-18 | 2003-05-08 | Duval Dean Larry | Enhanced ultrasonic cleaning devices |
US20030107302A1 (en) * | 2001-07-27 | 2003-06-12 | Michael Birth | Piezoelectric element and an oscillation transducer with a piezoelectric element |
US6653762B2 (en) * | 2000-04-19 | 2003-11-25 | Murata Manufacturing Co., Ltd. | Piezoelectric type electric acoustic converter |
US20100243008A1 (en) * | 2009-03-24 | 2010-09-30 | Paul Schmitt | Cleaning system for an electric shaver |
US20100242285A1 (en) * | 2009-03-24 | 2010-09-30 | Paul Schmitt | Cleaning system for an electric shaver |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1139313A (en) * | 1914-05-15 | 1915-05-11 | Frank Hoyt Stevens | Dish-washer. |
US1445359A (en) * | 1919-09-16 | 1923-02-13 | Scarborough | Apparatus for cleaning bottles and like containers |
US2102819A (en) * | 1937-02-23 | 1937-12-21 | Fernando M Ronci | Immersing and drying machine |
US2616820A (en) * | 1947-05-19 | 1952-11-04 | Saint Gobain | Vibratory cleansing of objects |
-
1954
- 1954-08-13 US US449613A patent/US2814575A/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1139313A (en) * | 1914-05-15 | 1915-05-11 | Frank Hoyt Stevens | Dish-washer. |
US1445359A (en) * | 1919-09-16 | 1923-02-13 | Scarborough | Apparatus for cleaning bottles and like containers |
US2102819A (en) * | 1937-02-23 | 1937-12-21 | Fernando M Ronci | Immersing and drying machine |
US2616820A (en) * | 1947-05-19 | 1952-11-04 | Saint Gobain | Vibratory cleansing of objects |
Cited By (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2980123A (en) * | 1955-11-14 | 1961-04-18 | Jerome H Lemelson | Ultrasonic apparatus |
US3022202A (en) * | 1956-04-09 | 1962-02-20 | Libbey Owens Ford Glass Co | Method of cleaning surfaces |
US2968584A (en) * | 1956-10-31 | 1961-01-17 | Corning Glass Works | Glass tube cleaning |
US2974070A (en) * | 1957-02-07 | 1961-03-07 | American Enka Corp | Process for cleaning spinnerets |
US2992142A (en) * | 1958-01-17 | 1961-07-11 | Detrex Chem Ind | Ultrasonic cleaning method |
US3047434A (en) * | 1958-03-28 | 1962-07-31 | Bendix Corp | Solutions and methods for radioactive decontamination |
US3085185A (en) * | 1959-05-12 | 1963-04-09 | Detrex Chem Ind | Ultrasonic cleaning apparatus |
US3068829A (en) * | 1959-11-13 | 1962-12-18 | Carl W Nuissl | Device for cleaning vessels |
US3233449A (en) * | 1960-10-06 | 1966-02-08 | Republic Steel Corp | Method and apparatus for ultrasonic testing of pipe |
US3253219A (en) * | 1961-06-01 | 1966-05-24 | Union Oil Co | Method using change of piezoelectric crystal frequency to determine corrosion rate and apparatus therefor |
US3291640A (en) * | 1963-05-27 | 1966-12-13 | Chemclean Corp | Ultrasonic cleaning process |
US3364067A (en) * | 1963-12-24 | 1968-01-16 | Gen Dynamics Corp | Method and apparatus for surface cleaning |
US3224213A (en) * | 1964-07-17 | 1965-12-21 | Jr Earl E Hoyt | Method for making and harvesting ice using ultrasonic vibrators |
US3448743A (en) * | 1966-11-07 | 1969-06-10 | R & D Suppliers Inc | Apparatus for cleaning containers |
US3628873A (en) * | 1969-02-22 | 1971-12-21 | Leitz Ernst Gmbh | Method of continuously determining the degree of pollution of translucent liquids and apparatus therefor |
US4036168A (en) * | 1973-09-10 | 1977-07-19 | Omnitech Inc. | Apparatus for coating articles |
US4082565A (en) * | 1975-12-15 | 1978-04-04 | Rino Sjolander | Method and apparatus for the removal of deposits from a fuel injection valve |
US4091495A (en) * | 1976-05-17 | 1978-05-30 | Aspenlind Ake Lars G | Gas cylinder washing, draining and/or drying apparatus |
US4106155A (en) * | 1976-10-06 | 1978-08-15 | Cortex Research Corporation | Apparatus for washing contaminated laboratory containers |
US4211744A (en) * | 1978-05-24 | 1980-07-08 | Biophysics Research & Consulting Corporation | Process for ultrasonic pasteurization |
US4377880A (en) * | 1981-02-27 | 1983-03-29 | The United States Of America As Represented By The United States Department Of Energy | Cleaning method and apparatus |
US4559664A (en) * | 1981-08-31 | 1985-12-24 | Prolic Ag | Automatic washing- and rinsing device for titration plates or the like |
US4525219A (en) * | 1983-04-11 | 1985-06-25 | Gard Corporation | Ampule cleaning and quality control system |
US4565942A (en) * | 1983-07-01 | 1986-01-21 | Murata Manufacturing Co., Ltd. | Energy trapped piezoelectric resonator liquid sensor |
US4582077A (en) * | 1983-08-22 | 1986-04-15 | Skoda, Koncernovy Podnik | Arrangement for cleaning of objects by means of a close ultrasonic field |
US4607652A (en) * | 1984-08-29 | 1986-08-26 | Yung Simon K C | Contact lens cleaning apparatus |
US4697605A (en) * | 1984-08-29 | 1987-10-06 | Smc Metal Tech Co., Ltd. | Contact lens cleaning apparatus |
US4754186A (en) * | 1986-12-23 | 1988-06-28 | E. I. Du Pont De Nemours And Company | Drive network for an ultrasonic probe |
US5254900A (en) * | 1989-06-23 | 1993-10-19 | Siemens Aktiengesellschaft | Broad beam ultrasonic transducer |
US5353823A (en) * | 1989-09-29 | 1994-10-11 | Starrfras Maschinen AG | Device for cleaning the fastening shank of a tool or of a toolholder |
US5355048A (en) * | 1993-07-21 | 1994-10-11 | Fsi International, Inc. | Megasonic transducer for cleaning substrate surfaces |
US5534076A (en) * | 1994-10-03 | 1996-07-09 | Verteg, Inc. | Megasonic cleaning system |
US5713101A (en) * | 1995-12-13 | 1998-02-03 | Jackson; Robert L. | Nozzles and container cleaning system |
EP0792699A2 (en) * | 1996-03-01 | 1997-09-03 | Pharma-Tech Co. Ltd. | Apparatus and process for ultrasonic cleaning |
EP0792699A3 (en) * | 1996-03-01 | 1998-06-10 | Pharma-Tech Co. Ltd. | Apparatus and process for ultrasonic cleaning |
US6684891B2 (en) | 1996-09-30 | 2004-02-03 | Verteq, Inc. | Wafer cleaning |
US6681782B2 (en) | 1996-09-30 | 2004-01-27 | Verteq, Inc. | Wafer cleaning |
US6295999B1 (en) | 1996-09-30 | 2001-10-02 | Verteq, Inc. | Wafer cleaning method |
US6463938B2 (en) | 1996-09-30 | 2002-10-15 | Verteq, Inc. | Wafer cleaning method |
US8771427B2 (en) | 1996-09-30 | 2014-07-08 | Akrion Systems, Llc | Method of manufacturing integrated circuit devices |
US8257505B2 (en) | 1996-09-30 | 2012-09-04 | Akrion Systems, Llc | Method for megasonic processing of an article |
US6140744A (en) * | 1996-09-30 | 2000-10-31 | Verteq, Inc. | Wafer cleaning system |
US7117876B2 (en) | 1996-09-30 | 2006-10-10 | Akrion Technologies, Inc. | Method of cleaning a side of a thin flat substrate by applying sonic energy to the opposite side of the substrate |
US6039059A (en) * | 1996-09-30 | 2000-03-21 | Verteq, Inc. | Wafer cleaning system |
US7518288B2 (en) | 1996-09-30 | 2009-04-14 | Akrion Technologies, Inc. | System for megasonic processing of an article |
US7268469B2 (en) | 1996-09-30 | 2007-09-11 | Akrion Technologies, Inc. | Transducer assembly for megasonic processing of an article and apparatus utilizing the same |
US7211932B2 (en) | 1996-09-30 | 2007-05-01 | Akrion Technologies, Inc. | Apparatus for megasonic processing of an article |
US20060175935A1 (en) * | 1996-09-30 | 2006-08-10 | Bran Mario E | Transducer assembly for megasonic processing of an article |
US20060180186A1 (en) * | 1996-09-30 | 2006-08-17 | Bran Mario E | Transducer assembly for megasonic processing of an article |
US6653762B2 (en) * | 2000-04-19 | 2003-11-25 | Murata Manufacturing Co., Ltd. | Piezoelectric type electric acoustic converter |
US6825593B2 (en) | 2000-04-19 | 2004-11-30 | Murata Manufacturing Co., Ltd. | Piezoelectric type electric acoustic converter |
US6897601B2 (en) * | 2001-07-27 | 2005-05-24 | Holmberg Gmbh & Co. Kg | Piezoelectric element and an oscillation transducer with a piezoelectric element |
US20030107302A1 (en) * | 2001-07-27 | 2003-06-12 | Michael Birth | Piezoelectric element and an oscillation transducer with a piezoelectric element |
US7004182B2 (en) * | 2001-10-18 | 2006-02-28 | The Procter & Gamble Company | Enhanced ultrasonic cleaning devices |
US20030084535A1 (en) * | 2001-10-18 | 2003-05-08 | Duval Dean Larry | Enhanced ultrasonic cleaning devices |
US20100243008A1 (en) * | 2009-03-24 | 2010-09-30 | Paul Schmitt | Cleaning system for an electric shaver |
US20100242285A1 (en) * | 2009-03-24 | 2010-09-30 | Paul Schmitt | Cleaning system for an electric shaver |
US8177918B2 (en) * | 2009-03-24 | 2012-05-15 | Rovcal, LLC | Cleaning system for an electric shaver |
US8939161B2 (en) | 2009-03-24 | 2015-01-27 | Spectrum Brands, Inc. | Cleaning system for an electric shaver |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US2814575A (en) | Method and apparatus for cleaning ampoules with the aid of ultrasonic vibration | |
US9776222B2 (en) | Method for removing contaminating particles from containers | |
US3071497A (en) | Method and apparatus for cleaning small glass containers | |
KR960039177A (en) | Semiconductor wafer cleaning apparatus and method | |
US4442852A (en) | Ultrasonic cleaner apparatus | |
US4200470A (en) | Method and apparatus for cleaning ampules or similar containers | |
JPS551114A (en) | Method and device for washing wafer | |
EP0792699A2 (en) | Apparatus and process for ultrasonic cleaning | |
US2003668A (en) | Apparatus for cleaning bottles | |
JPH07197268A (en) | Plating device for surface zipper | |
US2879575A (en) | Apparatus for producing concrete products on a floor | |
SU416111A1 (en) | DEVICE FOR CLEANING DETAILS | |
JPH10156297A (en) | Ultrasonic cleaning method and its device | |
JPH09290227A (en) | Ultrasonic washer and method thereof | |
FR2213788A1 (en) | Drying appts - to remove liquid esp water from non-absorbent esp flat articles | |
JPH0442530A (en) | Ultrasonic cleaning device | |
SU1519793A1 (en) | Method and apparatus for ultrasonic cleaning of articles | |
JPS649235B2 (en) | ||
SU1688950A1 (en) | Methods for cleaning vessels | |
SU580020A1 (en) | Method of cleaning articles with blind cavities | |
GB2192726A (en) | Method and apparatus for the stress testing of glass containers | |
JPH0290981A (en) | Cleaning and drying device for ampoule, bottle or the like | |
SU962234A2 (en) | Method for cleaning glass ampoules and appratus for cleaning glass ampoules | |
GB1065474A (en) | Apparatus for handling ampules | |
SU1146283A1 (en) | Method of manufacturing and filling ampoules |