US3166069A - Operating mechanism for automatic hypodermic syringes - Google Patents

Operating mechanism for automatic hypodermic syringes Download PDF

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US3166069A
US3166069A US89250A US8925061A US3166069A US 3166069 A US3166069 A US 3166069A US 89250 A US89250 A US 89250A US 8925061 A US8925061 A US 8925061A US 3166069 A US3166069 A US 3166069A
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Prior art keywords
syringe
shoulder
rod
spring
actuating rod
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Expired - Lifetime
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US89250A
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Enstrom Hans Gosta
Fredriksson Rune Gerold
Rudolf A I Lundgren
Nojd John Adolf
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AstraZeneca AB
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Astra AB
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock

Definitions

  • This invention deals with an operating mechanism for automatic hypodermic syringes, that is to say syringes where the injection occurs automatically after the mechanism has been released so that the injection needle is brought into an active position and the injection fluid is squirted out through the needle.
  • Automatic syringes are particularly intended for such civilian or military use where the patient gives himself an injection.
  • Syringes of this type are often kept for long periods in a charged condition, that is to say, they are ready for immediate use. It is therefore a prerequisite thatthe releasing device provides a guarantee against involuntary release as well as of satisfactory functioning when needed. Further it is important that after use the syringe can be reloaded in a simple way, that is to say, it must be easy to re-apply the tension so that the syringe is ready for further use when new injection fluid is inserted,
  • the operating mechanism comprises a spring-driven operating device for the moving parts of the syringe, a retaining catch for holding the operating device taut, as well as an arrangement for releasing the operating mechanism from the retaining catch, and is characterised in that it consists of at least two tongues of a springy material running along the body of the syringe and arranged to engage with as well as holding in a taut position, a spring-loaded rod that serves as a driving device and is arranged to move along the centre of the syringe body, and also in that the rear end of the syringe body is provided with a release arrangement which can be movedalong the syringe and which is arranged to engage withthe rear portions of the tongues and which, when moved towards the'body of the syringe, presses these tongues outwards so that they release the rod.
  • FIGS. 1 and 2 show an embodiment of the invention with FIG. 1 showing the arrangement in a loaded, secured state and FIG. 2 showing the same arrangement where the release has just occurred following the Withdrawal of the securing arrangement.
  • FIGS. 3 and 4 show a second embodiment, FIG. 3 in a loaded state, and FIG. 4 in a state of beginning release, analogous to FIG. 2.
  • FIGS. 1 and 2 consists of a substantially cylindrical portion 1 which, by means of threads 2, is designed to be screwed into the upper end of a hypodermic syringe, which is not shown.
  • portion 1 will constitute the rear part of the body of the syringe.
  • the rear part of the member 1 is divided into a num-' ber of preferably four, flexible tongues 13.
  • the tongues 3 are arranged to engage with a flange 5 on a rod 6 arranged in the cylindrical member 1, by means of heels i3.
  • This rod 6 is actuated by a coil-spiing 7 which endeavours to push it in the direction of the front part of the syringe.
  • the member 1 is surrounded by a cylindrical cover 8.
  • V has projections 9 arranged to engage with the upper ends 10 of the tongues 3 and to move these outwards w the cover 8 is pressed down to its extreme position.
  • a resilient split ring 11 which is furnished v a handle 12, preferably in the form of a nylon cord ranged round the member 1 so that it rests partly aga: the lower edge of the cover '8 and partly against a 3.4 on the member 1.
  • the device of FIGS. 3 and 4 differs from that of PK 1 and 2 only as regards the cover, designated 19 in PK 3 and 4.
  • the cylindrical portion of the cover is clos at its top by a member 13 which'is provided with p] jecting portions 17, arranged to engage with theup; portions 15 of the springy tongues which hold the sprir loaded rod in a taut position.
  • the upper portion of t wall of the cylindrical cover 19 has a thinner portion 1
  • the space between said portion 16 and the projectio 17 is so wide that the tongue portions 15 can enter in said space without changing their upward-outward dire tion. Compare with the embodiment of FlGS. 1 and where the tongue portion 1 must be bent from the po tion of FIG. 1 into the position of FIG. 2 when t mechanism is to be released. 7
  • An operating -mechanism for an automatic hyp dermic syringe of the type including a spring-driven o crating device for the moving parts of the syringe,- retaining catch for holding the operating device star and an arrangement for releasing the operating mec anism from the retaining catch, characterized in th said mechanism comprises a generally cylindrical hollc body the same being at one end thereof threaded to ma a threaded end of such syringe, a coil spring and an a tuating rod within the coil thereof, said coil spring at actuating rod being disposed within said hollow bod 7 said actuating rod being provided with a shoulder at tl 'rear end of the same which is remote from said threadt portion, a plurality of resilient tongues extending fro and, mounted on said hollow body rearwardly with r spectto said threaded portion and surrounding the a jacent rear portions of said actuating rod and coil sprin said tongues, being interiorly providedrwitha
  • mechanism comprises'a generally cylindrical hollow the same being at one end thereof threaded to mate readed end of such syringe, a coilspring and an iting rod within the coil thereof, said coil spring actuating rod being disposed within said hollow body, actuating rod being provided with a shoulder at rear end of the same'which is' remote from said tded portion, a plurality of resilient tongues extendfrom and mounted on said hollow body rearwardly movably inactivating said A release, arrangement.

Description

Jan. 19, 1965 H. s. ENSTROM ETAL OPERATING MECHANISM FOR AUTOMATIC HYPODERMIC SYRINGES Filed Feb. 14, 1961 Fig.1 Fig. 2
F i g. 4
I E 5 E g United States Patent 3,166,069 OPERATENG MECHANTSM FGR AUTGMATEC HYPQDEPMEQ SYRINGES Hans Gosta Enstrom, Gstertalfie, Rune Gerald Fredriltsson, .larna, Rudolf A. I. Lundgren, Overenhorna, and John Adolf Nojd, Sodertalje, Sweden, assigners to Alrtiebolaget Astra, Apotelrarnes Kemiska Fahrilrer, Sodertalje, Sweden, a company of Sweden Fiied Feb. 14, 1961, Ser. No. 39,256 Claims priority, application Sweden, Feb. 16, 196i),
1,549/0. a 3 Claims. (4C5. 123-213) This invention deals with an operating mechanism for automatic hypodermic syringes, that is to say syringes where the injection occurs automatically after the mechanism has been released so that the injection needle is brought into an active position and the injection fluid is squirted out through the needle. Automatic syringes are particularly intended for such civilian or military use where the patient gives himself an injection.
Syringes of this type are often kept for long periods in a charged condition, that is to say, they are ready for immediate use. It is therefore a prerequisite thatthe releasing device provides a guarantee against involuntary release as well as of satisfactory functioning when needed. Further it is important that after use the syringe can be reloaded in a simple way, that is to say, it must be easy to re-apply the tension so that the syringe is ready for further use when new injection fluid is inserted,
usually in the formof a full ampoule.
The operating mechanism according to the present invention comprises a spring-driven operating device for the moving parts of the syringe, a retaining catch for holding the operating device taut, as well as an arrangement for releasing the operating mechanism from the retaining catch, and is characterised in that it consists of at least two tongues of a springy material running along the body of the syringe and arranged to engage with as well as holding in a taut position, a spring-loaded rod that serves as a driving device and is arranged to move along the centre of the syringe body, and also in that the rear end of the syringe body is provided with a release arrangement which can be movedalong the syringe and which is arranged to engage withthe rear portions of the tongues and which, when moved towards the'body of the syringe, presses these tongues outwards so that they release the rod.
The invention will subsequently be described by reference to the accompanying drawing, where FIGS. 1 and 2 show an embodiment of the invention with FIG. 1 showing the arrangement in a loaded, secured state and FIG. 2 showing the same arrangement where the release has just occurred following the Withdrawal of the securing arrangement. FIGS. 3 and 4 show a second embodiment, FIG. 3 in a loaded state, and FIG. 4 in a state of beginning release, analogous to FIG. 2.
The arrangement according to FIGS. 1 and 2 consists of a substantially cylindrical portion 1 which, by means of threads 2, is designed to be screwed into the upper end of a hypodermic syringe, which is not shown. Thus the portion 1 will constitute the rear part of the body of the syringe.
The rear part of the member 1 is divided into a num-' ber of preferably four, flexible tongues 13. The tongues 3 are arranged to engage with a flange 5 on a rod 6 arranged in the cylindrical member 1, by means of heels i3. This rod 6 is actuated by a coil-spiing 7 which endeavours to push it in the direction of the front part of the syringe. The member 1 is surrounded by a cylindrical cover 8. V has projections 9 arranged to engage with the upper ends 10 of the tongues 3 and to move these outwards w the cover 8 is pressed down to its extreme position.
as to secure the mechanism against involuntary rele there is a resilient split ring 11, which is furnished v a handle 12, preferably in the form of a nylon cord ranged round the member 1 so that it rests partly aga: the lower edge of the cover '8 and partly against a 3.4 on the member 1.
When the mechanism is to be released one first p: out the ring 11 with the aid of the handle 12. Then 1 grips the cover 8 and 'jabs or pushes the front end of syringe against that part of the body where the inject is to be made. 7 The cover 8 'is pressed down over member 1, and the projections 9 press the obliquely" ranged ends it) of the tongues 3 outwardsrtowards inner wall of the cover 3, by which the heels 13 rele the flange 5 on the rod 6. The spring 7'n ow pushes 7 0 The inside of the bottom of said cover released rod 6 forward in the 'body of the syringe wards its front part;
The events that take place in the front part of hypodermic syringe, which is not shown, will not described here since they do not constitute any p of this invention. .1
When the injection is finished and the syringe is to prepared for immediate use the com lete operatin me anism is unscrewed from the front part of the body the syringe and the securing ring is replaced, and the c spring is compressed by pressing inthe rod 6 until a cl is heard. No special tool is required for this operatil but the rod can simply be pressed against a table, 3 instance, until it reaches the secured positionillustrai in FIG. 1, where the lower end of the rod reaches son what beyond the threaded portion of the cylindrical p tion 1. Thereafter the operating mechanism is screvs into an already prepared front part and the syringe again ready for use. 7
The device of FIGS. 3 and 4 differs from that of PK 1 and 2 only as regards the cover, designated 19 in PK 3 and 4. The cylindrical portion of the cover is clos at its top bya member 13 which'is provided with p] jecting portions 17, arranged to engage with theup; portions 15 of the springy tongues which hold the sprir loaded rod in a taut position. The upper portion of t wall of the cylindrical cover 19 has a thinner portion 1 The space between said portion 16 and the projectio 17 is so wide that the tongue portions 15 can enter in said space without changing their upward-outward dire tion. Compare with the embodiment of FlGS. 1 and where the tongue portion 1 must be bent from the po tion of FIG. 1 into the position of FIG. 2 when t mechanism is to be released. 7
What is claimed is: g 1. An operating -mechanism for an automatic hyp dermic syringe of the type including a spring-driven o crating device for the moving parts of the syringe,- retaining catch for holding the operating device star and an arrangement for releasing the operating mec anism from the retaining catch, characterized in th said mechanism comprises a generally cylindrical hollc body the same being at one end thereof threaded to ma a threaded end of such syringe, a coil spring and an a tuating rod within the coil thereof, said coil spring at actuating rod being disposed within said hollow bod 7 said actuating rod being provided with a shoulder at tl 'rear end of the same which is remote from said threadt portion, a plurality of resilient tongues extending fro and, mounted on said hollow body rearwardly with r spectto said threaded portion and surrounding the a jacent rear portions of said actuating rod and coil sprin said tongues, being interiorly providedrwitha first shou I der constituting a support for'therear end of saidcc der of said operating rod to hold the operating rod ring-loaded position, a release arrangement movable said hollow body and adapted to engage said dered tongue and which, when moved toward the ded end of said body, presses said shouldered tongue and with a second shoulder engaging the said with respect to said threaded portion and surrounding the adjacent rear portions of said actuating rod and coil spring, said tongues being interiorly provided with a first shoulder constituting a support for the rear end of said coil spring and with a second shoulder engaging the said shoulder of said operating rod to hold the operating rod in spring-loaded position, a release arrangement movable along said hollow body and adapted to engage said shouldered tongue and which, when moved toward the threaded end of said body, presses said shouldered tongue outwardly so as to release said spring-loaded actuating rod from said tongues, and latch means reng device for the moving parts of the syringe, a
ning catch for holding the operating device taut, an arrangement for releasing the operating mechn from the retaining catch, characterized in that mechanism comprises'a generally cylindrical hollow the same being at one end thereof threaded to mate readed end of such syringe, a coilspring and an iting rod within the coil thereof, said coil spring actuating rod being disposed within said hollow body, actuating rod being provided with a shoulder at rear end of the same'which is' remote from said tded portion, a plurality of resilient tongues extendfrom and mounted on said hollow body rearwardly movably inactivating said A release, arrangement.
References Cited by the Examiner UNITED STATES PATENTS 2,676,591 4/54 FOX 128-216 7 2,832,339 4/58 Sarnoffetal 12s- 21s 3,066,670 12/62 Stauifer.
FOREIGN PATENTS 331,375 1/59 Switzerland.
RICHARD. A. GAUDET, Primary Examiner.
JORDAN FRANKLIN, RICHARD J. HOFFMAN,
I Examiners.

Claims (1)

1. AN OPERATING MECHANISM FOR AN AUTOMATIC HYPODERMIC SYRINGE OF THE TYPE INCLUDING A SPRING-DRIVEN OPERATING DEVICE FOR THE MOVING PARTS OF THE SYRINGE, A RETAINING CATCH FOR HOLDING THE OPERATING DEVICE TAUT, AND AN ARRANGEMENT FOR RELEASING THE OPENING MECHANISM FROM THE RETAINING CATCH, CHARACTERIZED IN THAT SAID MECHANISM COMPRISES A GENERALLY CYLINDRICAL HOLLOW BODY THE SAME BEING AT ONE END THEREOF THREADED TO MATE A THREADED END OF SUCH SYRINGE, A COIL SPRING AND AN ACTUATING ROD WITHIN THE COIL THEREOF, SAID COIL SPRING AND ACTUATING ROD BEING DISPOSED WITHIN SAID HOLLOW BODY, SAID ACTUATING ROD BEING PROVIDED WITH A SHOULDER AT THE REAR END OF THE SAME WHICH IS REMOTE FROM SAID THREADED PORTION, A PLURALITY OF RESILIENT TONGUES EXTENDING FROM AND MOUNTED ON SAID HOLLOW BODY REARWARDLY WITH RESPECT TO SAID THREADED PORTION AND SURROUNDING THE ADJACENT REAR PORTIONS OF SAID ACTUATING ROD AND COIL SPRING, SAID TONGUES BEING INTERIORLY PROVIDED WITH A FIRST SHOULDER CONSTITUTING A SUPPORT FOR THE REAR END OF SAID COIL SPRING AND WITH A SECOND SHOULDER ENGAGING THE SAID SHOULDER OF SAID OPERATING ROD TO HOLD THE OPERATING ROD IN SPRING-LOADED POSITION, A RELEASE ARRANGEMENT MOVABLE ALONG SAID HOLLOW BODY AND ADAPTED TO ENGAGE SAID SHOULDERED TONGUE AND WHICH, WHEN MOVED TOWARD THE THREADED END OF SAID BODY, PRESSES SAID SHOULDER TONGUE OUTWARDLY SO AS TO RELEASE SAID SPRING-LOADED ACTUATING ROD FROM SAID TONGUES.
US89250A 1954-10-27 1961-02-14 Operating mechanism for automatic hypodermic syringes Expired - Lifetime US3166069A (en)

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SE154960 1954-10-27
SE831260 1960-08-31

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32922E (en) * 1983-01-13 1989-05-16 Paul D. Levin Blood sampling instrument
US6210369B1 (en) 1997-12-16 2001-04-03 Meridian Medical Technologies Inc. Automatic injector
WO2009114542A1 (en) 2008-03-10 2009-09-17 Antares Pharma, Inc. Injector safety device
US8915889B2 (en) 2008-08-05 2014-12-23 Antares Pharma, Inc. Multiple dosage injector
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676591A (en) * 1951-03-27 1954-04-27 Fox Dorothy Brown Hypodermic unit
US2832339A (en) * 1953-09-02 1958-04-29 Potter Pharmaceutical Corp Hypodermic injector
CH331375A (en) * 1957-05-31 1958-07-15 Stauffer Ferdinand Injection device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676591A (en) * 1951-03-27 1954-04-27 Fox Dorothy Brown Hypodermic unit
US2832339A (en) * 1953-09-02 1958-04-29 Potter Pharmaceutical Corp Hypodermic injector
CH331375A (en) * 1957-05-31 1958-07-15 Stauffer Ferdinand Injection device
US3066670A (en) * 1957-05-31 1962-12-04 Stato A G Hypodermic injection apparatus

Cited By (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32922E (en) * 1983-01-13 1989-05-16 Paul D. Levin Blood sampling instrument
US6210369B1 (en) 1997-12-16 2001-04-03 Meridian Medical Technologies Inc. Automatic injector
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9737670B2 (en) 2002-02-11 2017-08-22 Antares Pharma, Inc. Intradermal injector
US11446441B2 (en) 2005-01-24 2022-09-20 Antares Pharma, Inc. Prefilled syringe injector
US10478560B2 (en) 2005-01-24 2019-11-19 Antares Pharma, Inc. Prefilled syringe injector
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9629959B2 (en) 2005-01-24 2017-04-25 Antares Pharma, Inc. Prefilled syringe jet injector
US11547808B2 (en) 2006-05-03 2023-01-10 Antares Pharma, Inc. Two-stage reconstituting injector
US10688250B2 (en) 2006-05-03 2020-06-23 Antares Pharma, Inc. Two-stage reconstituting injector
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US9867949B2 (en) * 2008-03-10 2018-01-16 Antares Pharma, Inc. Injector safety device
US20180099099A1 (en) * 2008-03-10 2018-04-12 Antares Pharma, Inc. Injector Safety Device
US11684723B2 (en) 2008-03-10 2023-06-27 Antares Pharma, Inc. Injector safety device
WO2009114542A1 (en) 2008-03-10 2009-09-17 Antares Pharma, Inc. Injector safety device
US20110144594A1 (en) * 2008-03-10 2011-06-16 Antares Pharma, Inc. Injector safety device
US10709844B2 (en) * 2008-03-10 2020-07-14 Antares Pharma, Inc. Injector safety device
US8814834B2 (en) * 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
EP3636301A1 (en) * 2008-03-10 2020-04-15 Antares Pharma, Inc. Injector safety device
EP2990067A1 (en) * 2008-03-10 2016-03-02 Antares Pharma, Inc. Injector safety device
US20140336589A1 (en) * 2008-03-10 2014-11-13 Antares Pharma, Inc. Injector safety device
US8915889B2 (en) 2008-08-05 2014-12-23 Antares Pharma, Inc. Multiple dosage injector
US10555954B2 (en) 2009-03-20 2020-02-11 Antares Pharma, Inc. Hazardous agent injection system
US11497753B2 (en) 2009-03-20 2022-11-15 Antares Pharma, Inc. Hazardous agent injection system
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9750881B2 (en) 2009-03-20 2017-09-05 Antares Pharma, Inc. Hazardous agent injection system
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US10279131B2 (en) 2011-07-15 2019-05-07 Antares Pharma, Inc. Injection device with cammed RAM assembly
US10568809B2 (en) 2011-07-15 2020-02-25 Ferring B.V. Liquid-transfer adapter beveled spike
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US11185642B2 (en) 2011-07-15 2021-11-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US10821072B2 (en) 2012-04-06 2020-11-03 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
US11771646B2 (en) 2012-04-06 2023-10-03 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
US11446440B2 (en) 2012-05-07 2022-09-20 Antares Pharma, Inc. Needle assisted injection device having reduced trigger force
US10905827B2 (en) 2012-05-07 2021-02-02 Antares Pharma, Inc. Injection device with cammed ram assembly
US10357609B2 (en) 2012-05-07 2019-07-23 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US10881798B2 (en) 2013-02-11 2021-01-05 Antares Pharma, Inc. Needle assisted injection device having reduced trigger force
US11813435B2 (en) 2013-02-11 2023-11-14 Antares Pharma, Inc. Needle assisted injection device having reduced trigger force
US10610649B2 (en) 2013-03-11 2020-04-07 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US11628260B2 (en) 2013-03-11 2023-04-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system

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DK97473C (en) 1963-12-02
GB933975A (en) 1963-08-14
CH389165A (en) 1965-03-15

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