US3528406A - Flexible spring guide tip for insertion of vascular catheters - Google Patents
Flexible spring guide tip for insertion of vascular catheters Download PDFInfo
- Publication number
- US3528406A US3528406A US505610A US3528406DA US3528406A US 3528406 A US3528406 A US 3528406A US 505610 A US505610 A US 505610A US 3528406D A US3528406D A US 3528406DA US 3528406 A US3528406 A US 3528406A
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- US
- United States
- Prior art keywords
- spring guide
- wire
- flexible spring
- vascular catheters
- distal tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M25/09016—Guide wires with mandrils
- A61M25/09033—Guide wires with mandrils with fixed mandrils, e.g. mandrils fixed to tip; Tensionable wires
Definitions
- This invention relates to new and useful improvements in spring guides used primarily in vascular manipulations and more particularly seeks to provide a spring guide that has reinforced strength throughout the proximal portion but flexibility within the distal tip.
- the spring guide is then fed into the vessel generally under the fluoroscope until the desired point is reached which may or may not require considerable manipulation if there are branched vessels or curves concerned. Thereafter the catheter is passed over the flexible spring guide and fed into the desired position and the spring guide then withdrawn from the catheter unless both are needed for cooperative manipulation purposes.
- the guides consist of an outer case which is a closely wound stainless steel spring to form a continuous coil surrounding an inner bore which is then sealed at the distal end with a rounded tip or cap.
- a straight core wire is placed within the coil bore and is either freely movable within the guide or fixed within the guide about 3 cm. short of the distal tip which is left flexible for manipulation purposes.
- the distal tip has the consistency of the proximal portion or complete lack of reinforcement.
- an 0.014 wire has been braided over with a finer wire with the braid passing about 3 cm. beyond the primary wire and the entire unit placed within the spring guide and secured at both ends within the braided extension being with the tip portion of the spring guide. This is obviously complex and expensive, and
- wire diameter of the reinforcing core wire can be reduced in the distal tip relative to that in the proximal body portion to satisfactorily accomplish the above object.
- FIG. 1 is a longitudinal cross-section taken through a spring guide constructed in accordance with this invention.
- FIG. 2 is a similar longitudinal cross-section through a modifie Spring g i
- This invention as illustrated shows two modicfications of spring guides constructed in accordance with this invention but obviously others will fall within the scope thereof.
- a conventional spring guide 5 is shown in FIGS. 1 and 2 made up of continuous contiguous coil 6 with a proximal portion 7 and a distal tip 8. These represent .035 OD. spring guides, but the same principle is applicable to smaller sizes or larger sizes that may be made.
- the inner core wire has two portions, the proximal heavy portion 9 and the distal lighter portion 10 which coincides with the distal tip of the spring guide. Portion 9 is about .014" and portion 10 is about .010".
- wire 11 being approximately .006 and extending throughout the entire length of the spring guide and wire 12 being about .010" but extending only up to the beginning of the distal tip 8 of the spring guide.
- All three of the inner wires disclosed herein are fixed at the proximal end of the spring guide and wires 10 and 1 1 are fixed at the distal end thereof whereas wire 12 is fixed at the proximal end of the distal tip.
- both the spring guides and the inner core wires are stainless steel but the same principles are obviously applicable to any of the various materials from which a spring guide may be made.
- said wire core having a reduced cross-section within said distal tip portion and consisting of a first wire within said proximal portion and a second wire within said proximal portion and said distal tip.
Description
United States Patent Inventors Norman C. Jeckel;
Ronald N. Jeck el; Charles C. Roach, Glens Falls, New York Appl. No. 505,610
Filed Oct. 29, 1965 Patented Sept. 15, 1970 Assignee United States Catheter & Instrument Corporation Glens Falls, New York a corporation of Delaware FLEXIBLE SPRING GUIDE TIP FOR INSERTION OF VASCULAR CATHETERS 3 Claims, 2 Drawing Figs.
US. Cl. 128/341,128/348 Int. Cl A61b 5/02,
A6lm 23/00 Field ofSearch l28/2.05,
[56] References Cited UNITED STATES PATENTS 707,775 8/1902 Harris 128/349 812,020 2/ 1906 Crippen 27/24 2,118,631 5/1938 Wappler 128/349 2,684,069 7/ 1954 Donaldson et a1. 128/303 OTHER REFERENCES U. S.C.l. Catalogue, 1964, pages 29, 32 and 33 relied on.
Primary Examiner-Dalton L. Truluck Attorney-W. Saxton Seward ABSTRACT: A spring guide for use in connection with the insertion of cardiac or vascular catheters having internal reinforcement throughout its length, the reinforcing means having reduced stiffening effect within .the distal tip to provide relatively greater flexibility of the guide in the tip portion thereof.
Patented Sept. 15, 1970 3,528,406
,, ,v mm
IN VE N TOR NORMAN c. JEcKEL' RONALD 1v. JECKEL CHARLES c ROACH FLEXIBLE SPRING GUIDE TIP FOR INSERTION OF VASCULAR CATHETERS This invention relates to new and useful improvements in spring guides used primarily in vascular manipulations and more particularly seeks to provide a spring guide that has reinforced strength throughout the proximal portion but flexibility within the distal tip.
The marked advances in cardiac and vascular surgery in the past few years and other medical problems that require diagnostic study of the vascular beds and systems has led to the extensive use of cardiac or vascular catheters, particularly for retrograde aortography and angiocardiography, and less often to take blood samples, determine oxygen content, infuse medicaments, etc. at internal sites and various other uses that require the insertion of a relatively long catheter to an internal site that requires movement of the catheter into branch vessels at sharp angles relative to the feeding direction of the catheter.
The most common method for insertion of such catheters is the percutaneous technique described in 1953 by Sven Ivar Seldinger. In this procedure a local anaesthesia is ,administered and a skin puncture made at a small angle to the vessel (e.g. femoral in the leg or branchial in the arm) with an obturator positioned within a cannula. Once the unit has been properly located in the vessel, the obturator is removed and the flexible spring guide then inserted through the cannula into the vessel for a short distance. Pressure is then applied to hold the spring guide in place while the cannula is withdrawn. The spring guide is then fed into the vessel generally under the fluoroscope until the desired point is reached which may or may not require considerable manipulation if there are branched vessels or curves concerned. Thereafter the catheter is passed over the flexible spring guide and fed into the desired position and the spring guide then withdrawn from the catheter unless both are needed for cooperative manipulation purposes.
There are presently available spring guides made from stainless steel having outside diameter sizes from about 0.025" (pediatric), up to 0.054" and from about 100 to 150 cm. long which are used with correspondingly shorter catheters. The guides consist of an outer case which is a closely wound stainless steel spring to form a continuous coil surrounding an inner bore which is then sealed at the distal end with a rounded tip or cap. A straight core wire is placed within the coil bore and is either freely movable within the guide or fixed within the guide about 3 cm. short of the distal tip which is left flexible for manipulation purposes.
Thus the distal tip has the consistency of the proximal portion or complete lack of reinforcement. In some instances, an 0.014 wire has been braided over with a finer wire with the braid passing about 3 cm. beyond the primary wire and the entire unit placed within the spring guide and secured at both ends within the braided extension being with the tip portion of the spring guide. This is obviously complex and expensive, and
in any event, cannot be accomplished in smaller sizes such as 0.035 or 0.0025 OD.
Therefore, it is an object of this invention to provide a spring guide, the distal end of which has flexibility and strength intermediate to that of the proximal body portion of the spring guide.
We have found the wire diameter of the reinforcing core wire can be reduced in the distal tip relative to that in the proximal body portion to satisfactorily accomplish the above object.
With the above and other objects and features in view, the nature of which will be more apparent, the invention will be more fully understood by reference to the drawings the accompanying detailed description and the appended claims.
In the drawings:
FIG. 1 is a longitudinal cross-section taken through a spring guide constructed in accordance with this invention; and
FIG. 2 is a similar longitudinal cross-section through a modifie Spring g i This invention as illustrated shows two modicfications of spring guides constructed in accordance with this invention but obviously others will fall within the scope thereof.
A conventional spring guide 5 is shown in FIGS. 1 and 2 made up of continuous contiguous coil 6 with a proximal portion 7 and a distal tip 8. These represent .035 OD. spring guides, but the same principle is applicable to smaller sizes or larger sizes that may be made. As shown in FIG. I the inner core wire has two portions, the proximal heavy portion 9 and the distal lighter portion 10 which coincides with the distal tip of the spring guide. Portion 9 is about .014" and portion 10 is about .010".
As shown in FIG. 2 there are two core wires, wire 11 being approximately .006 and extending throughout the entire length of the spring guide and wire 12 being about .010" but extending only up to the beginning of the distal tip 8 of the spring guide. All three of the inner wires disclosed herein are fixed at the proximal end of the spring guide and wires 10 and 1 1 are fixed at the distal end thereof whereas wire 12 is fixed at the proximal end of the distal tip. Thus in both modifications there is provided an intermediate reinforcement and flexibility of the distal tip of the spring guide.
In the examples shown, both the spring guides and the inner core wires are stainless steel but the same principles are obviously applicable to any of the various materials from which a spring guide may be made. p I va ri ods chaii g e s; modifications and ramifications will, of course, be obvious to those skilled in the art and are considered to be within the scope of the appended claims hereto.
having a proximal portion, a flexible distal tip portion and a wire core extending throughout the entire length of both said 1 portions and fixed at the respective ends of said spring guide,
said wire core having a reduced cross-section within said distal tip portion and consisting of a first wire within said proximal portion and a second wire within said proximal portion and said distal tip.
ing the full length of the coil spring guide and a second elongated rod-like member of shorter length than said first member extending only through said proximal portion, said second member being substantially thicker in cross-section than said first member.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50561065A | 1965-10-29 | 1965-10-29 |
Publications (1)
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US3528406A true US3528406A (en) | 1970-09-15 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US505610A Expired - Lifetime US3528406A (en) | 1965-10-29 | 1965-10-29 | Flexible spring guide tip for insertion of vascular catheters |
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Cited By (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3612058A (en) * | 1968-04-17 | 1971-10-12 | Electro Catheter Corp | Catheter stylets |
US3731671A (en) * | 1971-10-21 | 1973-05-08 | Cordis Corp | Low-friction catheter guide |
US3837347A (en) * | 1972-04-20 | 1974-09-24 | Electro Catheter Corp | Inflatable balloon-type pacing probe |
US3906938A (en) * | 1974-09-03 | 1975-09-23 | Lake Region Manufacturing Comp | Coil spring wire guide |
US3973556A (en) * | 1975-06-20 | 1976-08-10 | Lake Region Manufacturing Company, Inc. | Smoothened coil spring wire guide |
US4080706A (en) * | 1975-04-22 | 1978-03-28 | Medrad, Inc. | Method of manufacturing catheter guidewire |
JPS5754410U (en) * | 1980-09-18 | 1982-03-30 | ||
WO1984004686A1 (en) * | 1983-05-27 | 1984-12-06 | Rene Gilliard | Probe head |
EP0132387A2 (en) * | 1983-07-21 | 1985-01-30 | Cook Incorporated | Catheter wire guide with movable mandril |
EP0142330A2 (en) * | 1983-11-10 | 1985-05-22 | Advanced Cardiovascular Systems, Inc. | Guide wire for catheters |
EP0200919A1 (en) * | 1985-05-04 | 1986-11-12 | ANGIOMED Aktiengesellschaft | Guide wire |
US4659328A (en) * | 1984-03-12 | 1987-04-21 | Biosearch Medical Products, Inc. | Stylet |
EP0247371A1 (en) * | 1986-05-23 | 1987-12-02 | Sarcem Sa | Catheter guide |
EP0254885A1 (en) * | 1986-07-29 | 1988-02-03 | Sarcem Sa | Remote controlled catheter guide |
US4757827A (en) * | 1987-02-17 | 1988-07-19 | Versaflex Delivery Systems Inc. | Steerable guidewire with deflectable tip |
US4779628A (en) * | 1987-06-12 | 1988-10-25 | Medrad, Inc. | Guidewire assembly having moveable core and low profile safety wire |
US4813434A (en) * | 1987-02-17 | 1989-03-21 | Medtronic Versaflex, Inc. | Steerable guidewire with deflectable tip |
US4815478A (en) * | 1987-02-17 | 1989-03-28 | Medtronic Versaflex, Inc. | Steerable guidewire with deflectable tip |
US4830023A (en) * | 1987-11-27 | 1989-05-16 | Medi-Tech, Incorporated | Medical guidewire |
WO1989006985A1 (en) * | 1988-01-27 | 1989-08-10 | Advanced Biomedical Devices, Inc. | Steerable guidewire for vascular system |
US4886067A (en) * | 1989-01-03 | 1989-12-12 | C. R. Bard, Inc. | Steerable guidewire with soft adjustable tip |
US4917102A (en) * | 1988-09-14 | 1990-04-17 | Advanced Cardiovascular Systems, Inc. | Guidewire assembly with steerable adjustable tip |
US4925445A (en) * | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
US4934380A (en) * | 1987-11-27 | 1990-06-19 | Boston Scientific Corporation | Medical guidewire |
US4940062A (en) * | 1988-05-26 | 1990-07-10 | Advanced Cardiovascular Systems, Inc. | Guiding member with deflectable tip |
US4947864A (en) * | 1989-03-13 | 1990-08-14 | Schneider (U.S.A.), Inc. A Pfizer Company | Guidewire exchange catheter |
US4984581A (en) * | 1988-10-12 | 1991-01-15 | Flexmedics Corporation | Flexible guide having two-way shape memory alloy |
US5059176A (en) * | 1989-12-21 | 1991-10-22 | Winters R Edward | Vascular system steerable guidewire with inflatable balloon |
US5168864A (en) * | 1991-09-26 | 1992-12-08 | Clarus Medical Systems, Inc. | Deflectable endoscope |
US5176149A (en) * | 1990-12-28 | 1993-01-05 | Nivarox-Far S.A. | Catheter guide support |
US5195968A (en) * | 1990-02-02 | 1993-03-23 | Ingemar Lundquist | Catheter steering mechanism |
US5207229A (en) * | 1989-12-21 | 1993-05-04 | Advanced Biomedical Devices, Inc. | Flexibility steerable guidewire with inflatable balloon |
US5254088A (en) * | 1990-02-02 | 1993-10-19 | Ep Technologies, Inc. | Catheter steering mechanism |
US5295493A (en) * | 1992-03-19 | 1994-03-22 | Interventional Technologies, Inc. | Anatomical guide wire |
US5345945A (en) * | 1990-08-29 | 1994-09-13 | Baxter International Inc. | Dual coil guidewire with radiopaque distal tip |
US5377690A (en) * | 1993-02-09 | 1995-01-03 | C. R. Bard, Inc. | Guidewire with round forming wire |
US5396902A (en) * | 1993-02-03 | 1995-03-14 | Medtronic, Inc. | Steerable stylet and manipulative handle assembly |
US5402799A (en) * | 1993-06-29 | 1995-04-04 | Cordis Corporation | Guidewire having flexible floppy tip |
US5409015A (en) * | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US5488959A (en) * | 1993-12-27 | 1996-02-06 | Cordis Corporation | Medical guidewire and welding process |
US5545200A (en) * | 1993-07-20 | 1996-08-13 | Medtronic Cardiorhythm | Steerable electrophysiology catheter |
US5605162A (en) * | 1991-10-15 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Method for using a variable stiffness guidewire |
US5662119A (en) * | 1991-08-28 | 1997-09-02 | Medtronic Inc. | Steerable stylet and manipulative handle assembly |
US5673707A (en) * | 1994-09-23 | 1997-10-07 | Boston Scientific Corporation | Enhanced performance guidewire |
US5695499A (en) * | 1994-10-27 | 1997-12-09 | Schneider (Usa) Inc. | Medical device supported by spirally wound wire |
US5749837A (en) * | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
US5769796A (en) * | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
US5772609A (en) * | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
US5830155A (en) * | 1995-10-27 | 1998-11-03 | Cordis Corporation | Guidewire assembly |
US5836892A (en) * | 1995-10-30 | 1998-11-17 | Cordis Corporation | Guidewire with radiopaque markers |
US5951568A (en) * | 1998-03-19 | 1999-09-14 | Schatz; Richard A. | Over the wire single operator catheter with wire stabilizer |
US5987344A (en) * | 1996-08-08 | 1999-11-16 | Medtronic, Inc. | Handle for catheter assembly with multifunction wire |
US6033378A (en) * | 1990-02-02 | 2000-03-07 | Ep Technologies, Inc. | Catheter steering mechanism |
US6139510A (en) * | 1994-05-11 | 2000-10-31 | Target Therapeutics Inc. | Super elastic alloy guidewire |
US20090234184A1 (en) * | 2008-03-17 | 2009-09-17 | Fujifilm Corporation | Endoscope |
WO2009131750A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic Vascular Inc. | Catheter flushing mandrel |
US20100022989A1 (en) * | 2008-07-25 | 2010-01-28 | Parasmo Ronald S | Steerable catheter and method of making the same |
US20100087780A1 (en) * | 2008-10-03 | 2010-04-08 | Cook Incorporated | Wire Guide having Variable Flexibility and Method of Use Thereof |
US7883474B1 (en) | 1993-05-11 | 2011-02-08 | Target Therapeutics, Inc. | Composite braided guidewire |
US9017246B2 (en) | 2010-11-19 | 2015-04-28 | Boston Scientific Scimed, Inc. | Biliary catheter systems including stabilizing members |
WO2019116313A1 (en) * | 2017-12-14 | 2019-06-20 | Acclarent, Inc. | Guidewire assembly with offset core wires |
-
1965
- 1965-10-29 US US505610A patent/US3528406A/en not_active Expired - Lifetime
Cited By (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3612058A (en) * | 1968-04-17 | 1971-10-12 | Electro Catheter Corp | Catheter stylets |
US3731671A (en) * | 1971-10-21 | 1973-05-08 | Cordis Corp | Low-friction catheter guide |
US3837347A (en) * | 1972-04-20 | 1974-09-24 | Electro Catheter Corp | Inflatable balloon-type pacing probe |
US3906938A (en) * | 1974-09-03 | 1975-09-23 | Lake Region Manufacturing Comp | Coil spring wire guide |
US4080706A (en) * | 1975-04-22 | 1978-03-28 | Medrad, Inc. | Method of manufacturing catheter guidewire |
US3973556A (en) * | 1975-06-20 | 1976-08-10 | Lake Region Manufacturing Company, Inc. | Smoothened coil spring wire guide |
JPS5754410U (en) * | 1980-09-18 | 1982-03-30 | ||
JPH0221045Y2 (en) * | 1980-09-18 | 1990-06-07 | ||
WO1984004686A1 (en) * | 1983-05-27 | 1984-12-06 | Rene Gilliard | Probe head |
EP0132387A3 (en) * | 1983-07-21 | 1986-03-19 | Cook Incorporated | Catheter wire guide with movable mandril |
EP0132387A2 (en) * | 1983-07-21 | 1985-01-30 | Cook Incorporated | Catheter wire guide with movable mandril |
US4925445A (en) * | 1983-09-16 | 1990-05-15 | Fuji Terumo Co., Ltd. | Guide wire for catheter |
EP0142330A3 (en) * | 1983-11-10 | 1986-07-23 | Advanced Cardiovascular System | Guide wire for catheters |
EP0142330A2 (en) * | 1983-11-10 | 1985-05-22 | Advanced Cardiovascular Systems, Inc. | Guide wire for catheters |
US4659328A (en) * | 1984-03-12 | 1987-04-21 | Biosearch Medical Products, Inc. | Stylet |
EP0200919A1 (en) * | 1985-05-04 | 1986-11-12 | ANGIOMED Aktiengesellschaft | Guide wire |
EP0247371A1 (en) * | 1986-05-23 | 1987-12-02 | Sarcem Sa | Catheter guide |
US4798598A (en) * | 1986-05-23 | 1989-01-17 | Sarcem S.A. | Guide for a catheter |
EP0254885A1 (en) * | 1986-07-29 | 1988-02-03 | Sarcem Sa | Remote controlled catheter guide |
US4787399A (en) * | 1986-07-29 | 1988-11-29 | Sarcem S.A. | Remote controlled catheter guide |
US4757827A (en) * | 1987-02-17 | 1988-07-19 | Versaflex Delivery Systems Inc. | Steerable guidewire with deflectable tip |
US4815478A (en) * | 1987-02-17 | 1989-03-28 | Medtronic Versaflex, Inc. | Steerable guidewire with deflectable tip |
US4813434A (en) * | 1987-02-17 | 1989-03-21 | Medtronic Versaflex, Inc. | Steerable guidewire with deflectable tip |
US4779628A (en) * | 1987-06-12 | 1988-10-25 | Medrad, Inc. | Guidewire assembly having moveable core and low profile safety wire |
US4830023A (en) * | 1987-11-27 | 1989-05-16 | Medi-Tech, Incorporated | Medical guidewire |
US4934380A (en) * | 1987-11-27 | 1990-06-19 | Boston Scientific Corporation | Medical guidewire |
WO1989006985A1 (en) * | 1988-01-27 | 1989-08-10 | Advanced Biomedical Devices, Inc. | Steerable guidewire for vascular system |
US4940062A (en) * | 1988-05-26 | 1990-07-10 | Advanced Cardiovascular Systems, Inc. | Guiding member with deflectable tip |
US4917102A (en) * | 1988-09-14 | 1990-04-17 | Advanced Cardiovascular Systems, Inc. | Guidewire assembly with steerable adjustable tip |
US4984581A (en) * | 1988-10-12 | 1991-01-15 | Flexmedics Corporation | Flexible guide having two-way shape memory alloy |
US4886067A (en) * | 1989-01-03 | 1989-12-12 | C. R. Bard, Inc. | Steerable guidewire with soft adjustable tip |
US4947864A (en) * | 1989-03-13 | 1990-08-14 | Schneider (U.S.A.), Inc. A Pfizer Company | Guidewire exchange catheter |
US5059176A (en) * | 1989-12-21 | 1991-10-22 | Winters R Edward | Vascular system steerable guidewire with inflatable balloon |
US5207229A (en) * | 1989-12-21 | 1993-05-04 | Advanced Biomedical Devices, Inc. | Flexibility steerable guidewire with inflatable balloon |
US5336182A (en) * | 1990-02-02 | 1994-08-09 | Ep Technologies, Inc. | Catheter steering mechanism |
US5531686A (en) * | 1990-02-02 | 1996-07-02 | Ep Technologies, Inc. | Catheter steering mechanism |
US5254088A (en) * | 1990-02-02 | 1993-10-19 | Ep Technologies, Inc. | Catheter steering mechanism |
US5395327A (en) * | 1990-02-02 | 1995-03-07 | Ep Technologies, Inc. | Catheter steering mechanism |
US5195968A (en) * | 1990-02-02 | 1993-03-23 | Ingemar Lundquist | Catheter steering mechanism |
US6033378A (en) * | 1990-02-02 | 2000-03-07 | Ep Technologies, Inc. | Catheter steering mechanism |
US5345945A (en) * | 1990-08-29 | 1994-09-13 | Baxter International Inc. | Dual coil guidewire with radiopaque distal tip |
US5176149A (en) * | 1990-12-28 | 1993-01-05 | Nivarox-Far S.A. | Catheter guide support |
US5662119A (en) * | 1991-08-28 | 1997-09-02 | Medtronic Inc. | Steerable stylet and manipulative handle assembly |
US5873842A (en) * | 1991-08-28 | 1999-02-23 | Medtronic, Inc. | Steerable stylet and manipulative handle assembly |
US5168864A (en) * | 1991-09-26 | 1992-12-08 | Clarus Medical Systems, Inc. | Deflectable endoscope |
US5605162A (en) * | 1991-10-15 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Method for using a variable stiffness guidewire |
US5957903A (en) * | 1991-10-15 | 1999-09-28 | Advanced Cardiovascular Systems, Inc. | Variable stiffness guidewire |
US5295493A (en) * | 1992-03-19 | 1994-03-22 | Interventional Technologies, Inc. | Anatomical guide wire |
US5396902A (en) * | 1993-02-03 | 1995-03-14 | Medtronic, Inc. | Steerable stylet and manipulative handle assembly |
US5377690A (en) * | 1993-02-09 | 1995-01-03 | C. R. Bard, Inc. | Guidewire with round forming wire |
US5769796A (en) * | 1993-05-11 | 1998-06-23 | Target Therapeutics, Inc. | Super-elastic composite guidewire |
US5749837A (en) * | 1993-05-11 | 1998-05-12 | Target Therapeutics, Inc. | Enhanced lubricity guidewire |
US5772609A (en) * | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
US5636642A (en) * | 1993-05-11 | 1997-06-10 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US7883474B1 (en) | 1993-05-11 | 2011-02-08 | Target Therapeutics, Inc. | Composite braided guidewire |
US5409015A (en) * | 1993-05-11 | 1995-04-25 | Target Therapeutics, Inc. | Deformable tip super elastic guidewire |
US5402799A (en) * | 1993-06-29 | 1995-04-04 | Cordis Corporation | Guidewire having flexible floppy tip |
US5545200A (en) * | 1993-07-20 | 1996-08-13 | Medtronic Cardiorhythm | Steerable electrophysiology catheter |
US5488959A (en) * | 1993-12-27 | 1996-02-06 | Cordis Corporation | Medical guidewire and welding process |
US6139510A (en) * | 1994-05-11 | 2000-10-31 | Target Therapeutics Inc. | Super elastic alloy guidewire |
US5673707A (en) * | 1994-09-23 | 1997-10-07 | Boston Scientific Corporation | Enhanced performance guidewire |
US5695499A (en) * | 1994-10-27 | 1997-12-09 | Schneider (Usa) Inc. | Medical device supported by spirally wound wire |
US20110144625A1 (en) * | 1995-05-26 | 2011-06-16 | Target Therapeutics, Inc. | Composite Braided Guidewire |
US5830155A (en) * | 1995-10-27 | 1998-11-03 | Cordis Corporation | Guidewire assembly |
US5836892A (en) * | 1995-10-30 | 1998-11-17 | Cordis Corporation | Guidewire with radiopaque markers |
US6156027A (en) * | 1996-08-08 | 2000-12-05 | Medtronic, Inc. | Handle for catheter assembly with multifunction wire |
US6169916B1 (en) | 1996-08-08 | 2001-01-02 | Medtronic Inc. | Electrophysiology catheter with multifunctional wire and method for making |
US5987344A (en) * | 1996-08-08 | 1999-11-16 | Medtronic, Inc. | Handle for catheter assembly with multifunction wire |
US5951568A (en) * | 1998-03-19 | 1999-09-14 | Schatz; Richard A. | Over the wire single operator catheter with wire stabilizer |
US20090234184A1 (en) * | 2008-03-17 | 2009-09-17 | Fujifilm Corporation | Endoscope |
US20090270838A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic Vascular, Inc. | Catheter Flushing Mandrel |
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