US3817837A - Enzyme amplification assay - Google Patents
Enzyme amplification assay Download PDFInfo
- Publication number
- US3817837A US3817837A US00304156A US30415672A US3817837A US 3817837 A US3817837 A US 3817837A US 00304156 A US00304156 A US 00304156A US 30415672 A US30415672 A US 30415672A US 3817837 A US3817837 A US 3817837A
- Authority
- US
- United States
- Prior art keywords
- ligand
- enzyme
- hydrogen
- bound
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9486—Analgesics, e.g. opiates, aspirine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
D C UNTERFEIT TO PROVIDE AN "ENZYME-BOUNDLIGAND OR LIGANG COUNTERFEIT TO PROVIDE AN "ENZYME-BOUNDLIGAND," AN EXTREMELY SENSITIVE METHOD IS PROVIDED FOR ASSAYING FOR LIGANDS. THE RECEPTOR WHEN BOUND TO THE ENZYME-BOUND-LIGAND SUBSTANTIALLY INHIBITS ENZYMATIC ACTIVITY, PROVIDING FOR DIFFERENT CATALYTIC EFFICIENCIES OF ENZYME-BOUND-LIGAND AND ENZYME-BOUND-LIGAND COMBINED WITH RECEPTOR. THE RECEPTOR, LIGAND AND ENZYME-BOUND-LIGAND ARE COMBINED IN AN ARBITRARY ORDER AND THE EFFECT OF THE PRESENCE OF LIGAND ON ENZYMATIC ACTIVITY DETERMINED. VARIOUS PROTOCOLS MAY BE USED FOR ASSAYING FOR ENNZYMATIC ACTIVITY AND RELATING TO THE RESULT TO THE AMOUNT OF LIGAND PRESENT.
Description
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00304156A US3817837A (en) | 1971-05-14 | 1972-11-06 | Enzyme amplification assay |
BE170633A BE846194Q (en) | 1971-05-14 | 1976-09-14 | DOSAGE BY ENZYMATIC AMPLIFICATION |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14360971A | 1971-05-14 | 1971-05-14 | |
US00304156A US3817837A (en) | 1971-05-14 | 1972-11-06 | Enzyme amplification assay |
Publications (1)
Publication Number | Publication Date |
---|---|
US3817837A true US3817837A (en) | 1974-06-18 |
Family
ID=26841233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US00304156A Expired - Lifetime US3817837A (en) | 1971-05-14 | 1972-11-06 | Enzyme amplification assay |
Country Status (2)
Country | Link |
---|---|
US (1) | US3817837A (en) |
BE (1) | BE846194Q (en) |
Cited By (910)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
US3879262A (en) * | 1972-05-11 | 1975-04-22 | Akzona Inc | Detection and determination of haptens |
US3932221A (en) * | 1971-06-09 | 1976-01-13 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Immunological isozyme determination method |
DE2521523A1 (en) * | 1974-06-28 | 1976-01-15 | Syva Co | LACTAM COMPOUNDS AND CONJUGATES |
US3959078A (en) * | 1973-05-18 | 1976-05-25 | Midwest Research Institute | Enzyme immobilization with a thermochemical-photochemical bifunctional agent |
DE2618511A1 (en) * | 1975-04-28 | 1976-11-04 | Miles Lab | METHOD OF DETERMINING A LIGAND IN A LIQUID MEDIUM AND MEANS OF IMPLEMENTING IT |
US4012285A (en) * | 1972-12-01 | 1977-03-15 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Analysis of isoenzyme patterns |
US4025501A (en) * | 1975-03-20 | 1977-05-24 | Syva Company | Polypeptide propoxyphene derivatives for immunoassay reagents |
US4043872A (en) * | 1975-02-20 | 1977-08-23 | Syva Company | Polyiodothyronine immunoassay |
US4069105A (en) * | 1977-03-03 | 1978-01-17 | Syva Company | Lidocaine antigens and antibodies |
FR2384259A1 (en) * | 1977-03-15 | 1978-10-13 | Snam Progetti | COMPOSITION INTENDED FOR THE DETERMINATION OF TRI-IODO THYRONINE AND DIAGNOSIS METHOD USING THIS COMPOSITION |
DE2805961A1 (en) * | 1977-04-15 | 1978-10-19 | Syva Co | THEOPHYLLINE ANTIGENS AND ANTIBODIES AND THEIR USE FOR THE DETERMINATION OF THEOPHYLLINE |
US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
DE2830862A1 (en) * | 1977-07-14 | 1979-02-01 | Syva Co | HOMOGENEOUS, COMPETITIVE ANTIENZYME BINDING TEST AND REAGENT FOR CARRYING OUT THE PROCEDURE |
US4168207A (en) * | 1977-08-03 | 1979-09-18 | Syva Company | TBG assay |
US4171244A (en) * | 1975-02-20 | 1979-10-16 | Syva Company | Enzyme-bound-polyidothyronine |
DE2913550A1 (en) * | 1978-04-05 | 1979-10-18 | Syva Co | ANALYTICAL PROCEDURE AND REAGENT FOR THE IMPLEMENTATION OF IT |
WO1979000882A1 (en) * | 1978-04-05 | 1979-11-01 | Syva Co | Macromolecular environment control in specific receptor assays |
US4230797A (en) * | 1975-04-28 | 1980-10-28 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a coenzyme as label |
US4233401A (en) * | 1977-07-14 | 1980-11-11 | Syva Company | Antienzyme homogeneous competitive binding assay |
US4234681A (en) * | 1978-07-21 | 1980-11-18 | The Regents Of The University Of California | Immobolized light emitting systems |
US4235969A (en) * | 1978-05-08 | 1980-11-25 | Syva Company | Procainamide antigen conjugates and antibodies |
US4239745A (en) * | 1978-11-22 | 1980-12-16 | Penicillin Assays, Inc. | Antibiotic detection method |
US4239852A (en) * | 1978-06-12 | 1980-12-16 | Penicillin Assays, Inc. | Antibiotic detection method |
US4241177A (en) * | 1978-08-28 | 1980-12-23 | Syva Company | Propanolol antigen conjugates and antibodies |
WO1980002800A1 (en) * | 1979-06-21 | 1980-12-24 | G Oster | Specific impending ovulation indicator |
US4244939A (en) * | 1978-06-12 | 1981-01-13 | Baxter Travenol Laboratories, Inc. | Barbituric acid tracers and their preparation |
WO1981000261A1 (en) * | 1979-07-26 | 1981-02-05 | Syva Co | Charge effects in immunoassays |
US4255329A (en) * | 1973-10-02 | 1981-03-10 | Syva Company | Double receptor fluorescent immunoassay |
WO1981001414A1 (en) * | 1979-11-19 | 1981-05-28 | Charles Hospital Dev | An improved method of non homogenous enzyme immunoassay |
EP0043285A1 (en) * | 1980-07-01 | 1982-01-06 | Dainippon Pharmaceutical Co., Ltd. | Method for determination of valproic acid and reagents therein |
US4318980A (en) * | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
EP0047455A2 (en) * | 1980-09-02 | 1982-03-17 | Syva Company | Single test compositions for immunoassays and method for their preparation |
EP0057731A1 (en) * | 1980-07-11 | 1982-08-18 | Syva Company | Valproate derivatives and their conjugates to antigenic materials, antibodies thereto and method for the determination of valproate in physiological fluids |
US4347312A (en) * | 1980-03-20 | 1982-08-31 | Research Triangle Institute | Detection of antibiotics in milk |
EP0061762A2 (en) | 1981-03-30 | 1982-10-06 | Baker Instruments Corporation | Nucleotide-based substrates |
US4372745A (en) * | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
DE3227474A1 (en) * | 1981-07-24 | 1983-02-10 | Fuji Photo Film Co., Ltd., Minami-Ashigara, Kanagawa | ANALYZING FILM AND ANALYZING METHOD USING THE SAME |
US4375414A (en) * | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
US4378428A (en) * | 1981-03-30 | 1983-03-29 | Baker Instruments Corporation | Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays |
US4446233A (en) * | 1982-05-05 | 1984-05-01 | E. I. Du Pont De Nemours And Company | Homogeneous immunoassay using covalent hybrid antibodies |
EP0110640A2 (en) * | 1982-11-19 | 1984-06-13 | Minnesota Mining And Manufacturing Company | Receptor-based histamine assay |
EP0117693A2 (en) * | 1983-02-25 | 1984-09-05 | The Upjohn Company | Enzyme-linked immunoassay, assay kits and pair-binding compounds |
US4472301A (en) * | 1982-05-27 | 1984-09-18 | Miles Laboratories, Inc. | Propranolol immunogen and antibodies |
US4474878A (en) * | 1975-09-29 | 1984-10-02 | Cordis Laboratories, Inc. | Sandwich EIA for antigen associated with hepatitis |
US4477576A (en) * | 1982-07-26 | 1984-10-16 | Mex Research Associates | Antigen assay method and kit |
EP0126631A1 (en) * | 1983-05-18 | 1984-11-28 | Syntex (U.S.A.) Inc. | Chloramphenicol derivatives, intermediates and processes therefor |
US4489157A (en) * | 1981-09-28 | 1984-12-18 | Syva Company | Chloramphenicol derivatives |
US4489156A (en) * | 1981-04-23 | 1984-12-18 | Syva Company | Chloramphenicol derivatives |
US4492751A (en) * | 1978-04-10 | 1985-01-08 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing an enzyme substrate as label |
US4495281A (en) * | 1982-10-21 | 1985-01-22 | Miles Laboratories, Inc. | Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives |
EP0137678A1 (en) * | 1983-08-29 | 1985-04-17 | Syntex (U.S.A.) Inc. | Ultrasonic enhanced immuno-reactions |
WO1985001747A1 (en) * | 1983-10-17 | 1985-04-25 | Inomedix, Incorporated | Device for rapid quantitative analysis of a fluid |
WO1985004397A1 (en) | 1984-03-23 | 1985-10-10 | Oncogen | Platelet related growth regulator |
US4550075A (en) * | 1983-06-22 | 1985-10-29 | Kallestad Laboratories, Inc. | Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor |
US4560648A (en) * | 1983-09-23 | 1985-12-24 | Syntex (U.S.A.) Inc. | Homogeneous enzyme immunoassay for ferritin |
US4587212A (en) * | 1982-05-26 | 1986-05-06 | Boots-Celltech Diagnostics Limited | Immunoassay |
DE2660911C2 (en) * | 1975-02-20 | 1986-05-28 | Syva Co., Palo Alto, Calif. | Method for the detection or determination of a ligand |
EP0185432A2 (en) * | 1984-12-21 | 1986-06-25 | SCLAVO S.p.A. | Immunoenzymatic method for the determination of analytes, and composition suitable to the purpose |
US4604365A (en) * | 1981-06-02 | 1986-08-05 | Electro-Nucleonics, Inc. | Immunoprecipitation assay |
US4606855A (en) * | 1982-07-26 | 1986-08-19 | Mex Research Associates C/O Leon Reimer | Monoclonal antibody to digoxin |
US4608252A (en) * | 1981-04-23 | 1986-08-26 | Syntex (U.S.A.) Inc. | Chloramphenicol derivatives antigens and antibodies |
EP0201716A2 (en) | 1985-04-08 | 1986-11-20 | Bristol-Myers Squibb Company | Expression of immunologically reactive viral proteins |
EP0204523A2 (en) * | 1985-05-31 | 1986-12-10 | Syntex (U.S.A.) Inc. | Glucose-6-phosphate dehydrogenase conjugates, their preparation and use |
US4629688A (en) * | 1975-04-28 | 1986-12-16 | Miles Laboratories, Inc. | Homogeneous specific binding assay method |
US4642285A (en) * | 1975-09-29 | 1987-02-10 | Diamedix Corporation | Sandwich EIA for antigen |
US4654311A (en) * | 1984-06-15 | 1987-03-31 | Syntex (U.S.A.) Inc. | Serum pretreatment for digoxin assay |
US4708929A (en) * | 1984-10-29 | 1987-11-24 | Microgenics Corporation | Methods for protein binding enzyme complementation assays |
US4716109A (en) * | 1983-01-31 | 1987-12-29 | Boots-Celltech Diagnostics Limited | Immunoassay |
US4719176A (en) * | 1983-10-31 | 1988-01-12 | Klotz Irving M | Enzyme-free diagnostic binding reagents |
US4721704A (en) * | 1986-05-09 | 1988-01-26 | Peninsula Laboratories, Inc. | Potent synthetic atrial peptide analogs |
USRE32696E (en) * | 1975-09-04 | 1988-06-14 | Akzona Incorporated | Enzymatic immunological method for determination of antigens and antibodies |
US4780409A (en) * | 1985-05-02 | 1988-10-25 | Genetic Systems Corporation | Thermally induced phase separation immunoassay |
US4785080A (en) * | 1981-03-30 | 1988-11-15 | Baker Instruments Corporation | Labeled analytes |
US4791055A (en) * | 1978-04-10 | 1988-12-13 | Miles Inc. | Homogenous specific binding assay reagent system and labeled conjugates |
US4791068A (en) * | 1984-06-22 | 1988-12-13 | Scripps Clinic And Research Foundation | Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators |
US4830786A (en) * | 1986-02-27 | 1989-05-16 | Syntex (U.S.A.) Inc. | Squaraine dyes |
US4868132A (en) * | 1987-02-03 | 1989-09-19 | Abbott Laboratories | Fluorescence polarization immunoassay for amphetamine/methamphetamine |
US4888276A (en) * | 1986-06-26 | 1989-12-19 | Minnesota Mining And Manufacturing Company | Method and composition for the diagnosis of Lyme disease |
US4889800A (en) * | 1985-08-12 | 1989-12-26 | Scripps Clinic And Research Foundation | Synthetic polypeptides and receptor molecules derived therefrom and methods of use |
AU592324B2 (en) * | 1984-10-29 | 1990-01-11 | Roche Diagnostics Corporation | Mehods for protein binding enzyme complementation assays |
US4946958A (en) * | 1981-12-11 | 1990-08-07 | The Welsh National School Of Medicine | Chemiluminescent acridinium labelling compounds |
EP0421589A2 (en) * | 1989-08-15 | 1991-04-10 | Microgenics Corporation | Drug screening assay |
US5057430A (en) * | 1988-09-15 | 1991-10-15 | Biotronic Systems Corporation | Biochemical sensor responsive to bubbles |
US5073629A (en) * | 1989-01-23 | 1991-12-17 | Abbott Laboratories | Methadone fluorescence polarization immunoassay |
US5089388A (en) * | 1983-04-19 | 1992-02-18 | Syntex (U.S.A.) Inc. | Antibodies for salicylate and their preparation |
US5101015A (en) * | 1989-04-10 | 1992-03-31 | Abbott Laboratories | Reagents for an amphetamine-class fluorescence polarization immunoassay |
US5103021A (en) * | 1982-04-02 | 1992-04-07 | Syntex (U.S.A.) Inc. | Acetaminophen analogs, antigens, and antibodies |
US5143852A (en) * | 1990-09-14 | 1992-09-01 | Biosite Diagnostics, Inc. | Antibodies to ligand analogues and their utility in ligand-receptor assays |
US5248791A (en) * | 1989-04-10 | 1993-09-28 | Abbott Laboratories | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay |
US5260441A (en) * | 1986-07-14 | 1993-11-09 | Abbott Laboratories | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
US5273885A (en) * | 1992-07-31 | 1993-12-28 | Syntex (U.S.A.) Inc. | Conjugates of monophenyl thyroid analogs useful in assays |
US5279937A (en) * | 1992-04-30 | 1994-01-18 | Detechnology Canada | Use of macroglobulins to improve the signal-to-background ratio in affinity binding assays |
US5329019A (en) * | 1986-02-27 | 1994-07-12 | Syntex (U.S.A.) Inc. | Squaraine dye compounds |
US5328828A (en) * | 1988-12-23 | 1994-07-12 | Syntex (U.S.A.) Inc. | Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine |
US5334513A (en) * | 1988-05-17 | 1994-08-02 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5358931A (en) * | 1990-01-17 | 1994-10-25 | The Regents Of The University Of California | Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications |
US5358690A (en) * | 1989-01-10 | 1994-10-25 | Lamina, Ltd. | Environmental sample collection and membrane testing device |
US5468647A (en) * | 1988-05-17 | 1995-11-21 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
EP0699754A1 (en) | 1994-08-12 | 1996-03-06 | Myriad Genetics, Inc. | Method for diagnosing a predisposition for breast and ovarian cancer |
EP0705903A1 (en) | 1994-08-12 | 1996-04-10 | Myriad Genetics, Inc. | In vivo mutations and polymorphisms in the 17q-linked breast and ovarian cancer susceptibility gene |
US5516647A (en) * | 1993-11-05 | 1996-05-14 | Abbott Laboratories | Compounds useful as alkaline phosphatase inhibitors and therapeutic agents |
US5516639A (en) * | 1993-07-22 | 1996-05-14 | Mayo Foundation For Medical Education And Research | Antibodies specific for human prostate glandular kallkrein |
US5518890A (en) * | 1992-11-20 | 1996-05-21 | Mccormick & Company, Inc. | Method and apparatus for the quantitation and separation of contaminants from particulate materials |
US5527686A (en) * | 1991-07-29 | 1996-06-18 | Serex, Inc. | Differential binding affinities and dissociation assays based thereon |
US5532138A (en) * | 1990-04-26 | 1996-07-02 | Behringwerke Ag | Method and kits for determining peroxidatively active catalysts |
WO1997001097A1 (en) * | 1995-06-22 | 1997-01-09 | Serex, Inc. | Receptor:release ligand (reland) complexes and assays and kits based thereon |
US5605800A (en) * | 1978-04-13 | 1997-02-25 | Institut Pasteur | Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method |
US5639624A (en) * | 1989-03-14 | 1997-06-17 | Board Of Regents Of The University Of Nebraska | Monoclonal antibodies specific for metallic cations and method therefor |
US5643732A (en) * | 1971-05-20 | 1997-07-01 | Strahilevitz; Meir | Immunological assay methods |
EP0785216A1 (en) | 1995-12-18 | 1997-07-23 | Myriad Genetics, Inc. | Chomosome 13-linked breast cancer susceptibility gene BRCA2 |
US5679526A (en) * | 1989-01-10 | 1997-10-21 | Biosite Diagnostics Incorporated | Threshold ligand-receptor assay |
US5684144A (en) * | 1993-07-28 | 1997-11-04 | University Of North Texas | Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof |
US5726023A (en) * | 1993-03-17 | 1998-03-10 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
US5808074A (en) * | 1996-02-02 | 1998-09-15 | Georgetown University | Benzoylecgonine conjugate diagnostic reagents |
US5843634A (en) * | 1993-03-09 | 1998-12-01 | Abbott Laboratories | Genetically engineered enzymes and their conjugates for diagnostic assays |
US5856083A (en) * | 1994-05-06 | 1999-01-05 | Pharmacopeia, Inc. | Lawn assay for compounds that affect enzyme activity or bind to target molecules |
US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
US5876928A (en) * | 1978-04-13 | 1999-03-02 | Institut Pasteur | Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method |
US5879894A (en) * | 1993-03-19 | 1999-03-09 | Chiron Diagnostics Corporation | Long emission wavelength chemiluminescent compounds and their use in test assays |
US5882644A (en) * | 1996-03-22 | 1999-03-16 | Protein Design Labs, Inc. | Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof |
US5929049A (en) * | 1997-08-08 | 1999-07-27 | Dade Behring Marburg Gmbh | Polysaccharide conjugates of biomolecules |
US5939272A (en) * | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
WO1999045124A2 (en) | 1998-03-04 | 1999-09-10 | Genencor International, Inc. | Modified forms of pullulanase |
WO1999064447A1 (en) * | 1998-06-09 | 1999-12-16 | Immco Diagnostics | Solution-phase elisa |
US6013471A (en) * | 1994-05-10 | 2000-01-11 | Hybritech Incorporated | DNA encoding hK2 variant polypeptides |
US6033890A (en) * | 1993-04-08 | 2000-03-07 | Behring Diagnostics Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
WO2000015824A1 (en) | 1998-09-13 | 2000-03-23 | Karolinska Innovations Ab | Transfer method for specific cellular localisation of nucleic acids |
US6060260A (en) * | 1998-02-27 | 2000-05-09 | Dade Behring Inc. | Methods for reducing adsorption in an assay |
US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
US6103237A (en) * | 1993-07-22 | 2000-08-15 | Hybritech Incorporated | Stable variant hK2 polypeptide |
US6127338A (en) * | 1997-04-01 | 2000-10-03 | Calyx Therapeutics, Inc. | Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes |
US6129917A (en) * | 1996-03-22 | 2000-10-10 | The University Of Georgia Research Foundation, Inc. | Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods |
US6153442A (en) * | 1998-05-20 | 2000-11-28 | Dade Behring Inc. | Reagents and methods for specific binding assays |
WO2000073451A1 (en) | 1999-06-01 | 2000-12-07 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
US6159698A (en) * | 1996-07-18 | 2000-12-12 | Dade Behring Marburg Gmbh | Reagents for assays for mycophenolic acid |
US6171801B1 (en) | 1996-07-18 | 2001-01-09 | Dade Behring Marburg Gmbh | Methods for releasing a ligand from a complex |
US6180411B1 (en) | 1997-08-01 | 2001-01-30 | The Regents Of The University Of California | Light-triggered indicators that memorize analyte concentrations |
US6187563B1 (en) | 1998-08-07 | 2001-02-13 | Yale University | βIV-spectrin-polypeptides and nucleic acids encoding same |
US6207153B1 (en) | 1996-05-22 | 2001-03-27 | Viventia Biotech, Inc. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
US6228638B1 (en) | 1997-07-11 | 2001-05-08 | University Of North Texas, Health Science Center At Fort Worth | Escherichia coli CSRB gene and RNA encoded thereby |
US6228575B1 (en) | 1996-02-08 | 2001-05-08 | Affymetrix, Inc. | Chip-based species identification and phenotypic characterization of microorganisms |
US6235486B1 (en) | 1997-06-20 | 2001-05-22 | Mayo Foundation For Medical Education & Research | Method for detection of breast cancer |
US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
US6262265B1 (en) | 1999-06-18 | 2001-07-17 | Microgenics Corporation | Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay |
US6297060B1 (en) | 1990-03-12 | 2001-10-02 | Biosite Diagnostics, Inc. | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
US6303325B1 (en) | 1998-05-29 | 2001-10-16 | Dade Behring Inc. | Method for detecting analytes |
US6303344B1 (en) | 1996-12-18 | 2001-10-16 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6312901B2 (en) | 1996-07-08 | 2001-11-06 | Burstein Technologies, Inc. | Spatially addressable, cleavable reflective signal elements, assay device and method |
US6326136B1 (en) | 1988-04-01 | 2001-12-04 | Digene Corporation | Macromolecular conjugate made using unsaturated aldehydes |
US6331275B1 (en) | 1996-07-08 | 2001-12-18 | Burstein Technologies, Inc. | Spatially addressable, cleavable reflective signal elements, assay device and method |
US6342349B1 (en) | 1996-07-08 | 2002-01-29 | Burstein Technologies, Inc. | Optical disk-based assay devices and methods |
WO2002020569A2 (en) | 2000-09-08 | 2002-03-14 | Schering Corporation | Mammalian genes; related reagents and methods |
US6391980B1 (en) | 1987-05-19 | 2002-05-21 | Aventis Pharmaceuticals Products, Inc. | Activated and conjugated polystyrene substrate |
US20020061580A1 (en) * | 1997-11-20 | 2002-05-23 | Estell David A. | Alpha/beta hydrolase-fold enzymes |
US6403807B1 (en) | 1999-07-06 | 2002-06-11 | Surromed, Inc. | Bridged fluorescent dyes, their preparation and their use in assays |
US6406855B1 (en) | 1994-02-17 | 2002-06-18 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6410687B1 (en) | 1998-04-14 | 2002-06-25 | The Regents Of The University Of California | Polypeptides for the detection of microtubule depolymerization inhibitors |
US6414152B1 (en) | 1981-12-11 | 2002-07-02 | University Of Wales College Of Medicine Of Heath Park | Luminescent labelling material and procedures |
US20020106661A1 (en) * | 1996-07-08 | 2002-08-08 | Burstein Laboratories, Inc. | Optical disk-based assay devices and methods |
US6433155B1 (en) | 1996-09-24 | 2002-08-13 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20020110860A1 (en) * | 2000-09-18 | 2002-08-15 | Sierd Bron | Twin-arginine translocation in Bacillus |
GR20000100255A (en) * | 2000-07-26 | 2002-09-06 | Αυτοματοι Αναλυτες Και Διαγνωστικα Αντιδραστηρια Medicon Hellas.. | DEVELOPMENT OF A NEW HOMOGENEOUS IMMUNOENZYMIC METHOD FOR THE PRODUCTION OF A CLINICAL LABORATORY TEST SYSTEM (kit) FOR THE QUANTIFICATION OF THYROXINE AND TRIIODOTHYRONINE IN HUMAN SERUM, UTILIZING POLYIODOTHYRONINE CONJUGATED WITH GLYCOGEN PHOSPHO.... |
US20020127641A1 (en) * | 1997-09-15 | 2002-09-12 | Estell David A. | Proteases from gram-positive organisms |
US20020137681A1 (en) * | 1999-07-06 | 2002-09-26 | Lawrence Steinman | Treatment of demyelinating autoimmune disease with ordered peptides |
US6458557B1 (en) | 1997-11-20 | 2002-10-01 | Genencor International, Inc. | Enhancing growth in gram-positive microorganisms using formate supplementation and inactivation of formate-associated transport proteins |
US20020154615A1 (en) * | 2000-01-28 | 2002-10-24 | Martin Hans | Detection method and device |
US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US20020165149A1 (en) * | 2000-12-08 | 2002-11-07 | Kranz David M. | Mutated class II major histocompatibility proteins |
US6479263B1 (en) | 1996-11-14 | 2002-11-12 | Baylor College Of Medicine | Method for detection of micrometastatic prostate cancer |
US20020172980A1 (en) * | 2000-11-27 | 2002-11-21 | Phan Brigitte Chau | Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems |
US20020187471A1 (en) * | 1996-10-01 | 2002-12-12 | Cech Thomas R. | Novel telomerase |
US20020187467A1 (en) * | 1998-04-03 | 2002-12-12 | Thomas Gingeras | Mycobacterial rpob sequences |
US20020192839A1 (en) * | 1998-03-30 | 2002-12-19 | Epitope, Inc. | Collection device for single step assay of oral fluids |
US20030003464A1 (en) * | 2000-11-27 | 2003-01-02 | Phan Brigitte C. | Dual bead assays including optical biodiscs and methods relating thereto |
US6506579B1 (en) | 1997-07-15 | 2003-01-14 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms using SecG |
US6521421B1 (en) | 1997-07-16 | 2003-02-18 | Genencor International, Inc. | Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same |
US6521440B1 (en) | 1997-09-15 | 2003-02-18 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20030054446A1 (en) * | 2000-11-29 | 2003-03-20 | Weber Bernard H. F. | Novel retina-specific human proteins C7orf9, C12orf7, MPP4 and F379 |
US20030064364A1 (en) * | 1996-01-23 | 2003-04-03 | Lockhart David J. | Nucleic acid analysis techniques |
US6544792B1 (en) | 1999-12-21 | 2003-04-08 | Genencor International, Inc. | Production of secreted polypeptides |
WO2003030835A2 (en) | 2001-10-12 | 2003-04-17 | Schering Corporation | Use of bispecific antibodies to regulate immune responses |
US20030073248A1 (en) * | 2001-09-28 | 2003-04-17 | J.W. Roth | Bovine pregnancy test |
US20030078177A1 (en) * | 1997-12-30 | 2003-04-24 | Estell David A. | Proteases from gram positive organisms |
US20030082596A1 (en) * | 2001-08-08 | 2003-05-01 | Michael Mittmann | Methods of genetic analysis of probes: test3 |
WO2003043524A2 (en) | 2001-11-20 | 2003-05-30 | The Curators Of The University Of Missouri | Compositions and methods for accurate early pregnancy diagnosis |
US20030104355A1 (en) * | 2001-11-02 | 2003-06-05 | Caili Wang | Adapter-directed display systems |
US20030105770A1 (en) * | 2001-11-26 | 2003-06-05 | Macleod Stewart | Extending a directory schema independent of schema modification |
WO2003046201A2 (en) | 2001-11-21 | 2003-06-05 | Kimberly-Clark Worldwide, Inc. | Detection and identification of enteric bacteria |
US20030104410A1 (en) * | 2001-03-16 | 2003-06-05 | Affymetrix, Inc. | Human microarray |
US20030108927A1 (en) * | 2000-04-03 | 2003-06-12 | Kathryn Leishman | Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases |
US20030118593A1 (en) * | 1997-07-08 | 2003-06-26 | Dan Michael D. | Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
US6599731B1 (en) | 1997-12-30 | 2003-07-29 | Genencor International, Inc. | Proteases from gram positive organisms |
EP1333094A2 (en) | 1996-10-01 | 2003-08-06 | Geron Corporation | Human telomerase catalytic subunit |
US20030158070A1 (en) * | 1997-07-15 | 2003-08-21 | Estell David A. | Proteases from gram-positive organisms |
US20030157642A1 (en) * | 1997-07-15 | 2003-08-21 | Caldwell Robert M. | Increasing production of proteins in gram-positive microorganisms |
US20030158133A1 (en) * | 2001-08-01 | 2003-08-21 | Movsesian Matthew A. | Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases |
US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
WO2003072799A2 (en) | 2002-02-22 | 2003-09-04 | The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Brother of the regulator of imprinted sites (boris) |
US20030170678A1 (en) * | 2001-10-25 | 2003-09-11 | Neurogenetics, Inc. | Genetic markers for Alzheimer's disease and methods using the same |
US20030180757A1 (en) * | 1996-01-23 | 2003-09-25 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US6630328B2 (en) | 1909-07-15 | 2003-10-07 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms |
US20030220475A1 (en) * | 2001-04-03 | 2003-11-27 | Fields Howard A. | Neutralizing immunogenic hev polypepetides |
US20030224373A1 (en) * | 2002-06-04 | 2003-12-04 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes |
US20030224452A1 (en) * | 2002-05-02 | 2003-12-04 | Mark Colgin | Pregnancy detection |
US20030224380A1 (en) * | 2001-10-25 | 2003-12-04 | The General Hospital Corporation | Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases |
US20030232979A1 (en) * | 1998-07-31 | 2003-12-18 | Mcgall Glenn | Nucleic acid labeling compounds |
US6670196B1 (en) | 1997-05-14 | 2003-12-30 | Biosite, Inc. | Rapid evaluation of the ratio of biological molecules |
US6673914B1 (en) | 1998-01-22 | 2004-01-06 | John Wayne Cancer Institute | Human tumor-associated gene |
US6673623B1 (en) | 2000-09-12 | 2004-01-06 | Novocure, Inc. | Methods and compositions that control lipid production |
US20040009164A1 (en) * | 2002-05-01 | 2004-01-15 | Jonathan Reeves | PSP94 diagnostic reagents and assays |
US6699969B1 (en) | 1998-04-14 | 2004-03-02 | The Regents Of The University Of California | Assays for the detection of microtubule depolymerization inhibitors |
US20040044198A1 (en) * | 2002-07-02 | 2004-03-04 | Pandey Ravindra K. | Efficient synthesis of pyropheophorbide a and its derivatives |
WO2004037251A1 (en) | 2002-10-24 | 2004-05-06 | Sterix Limited | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2 |
US20040101892A1 (en) * | 1996-01-23 | 2004-05-27 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20040106158A1 (en) * | 2002-10-21 | 2004-06-03 | Tabassum Naqvi | IP3 protein binding assay |
US20040126868A1 (en) * | 1997-07-15 | 2004-07-01 | Estell David A. | Gram-positive microorganisms with an inactivated cysteine protease-3 |
US6759243B2 (en) | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
US20040132109A1 (en) * | 2001-01-23 | 2004-07-08 | Masato Enari | Method |
US6794179B2 (en) | 1997-12-30 | 2004-09-21 | Genencor International, Inc. | Proteases from gram positive organisms |
US20040210045A1 (en) * | 1996-01-23 | 2004-10-21 | Mcgall Glenn | Nucleic acid labeling compounds |
US20040214248A1 (en) * | 2001-04-06 | 2004-10-28 | Roberts David D | Use of semenogelin in the diagnosis, prognosis and treatment of cancer |
WO2004096157A2 (en) | 2003-03-07 | 2004-11-11 | New England Medical Center Hospitals, Inc. | Treatment of igai deposition diseases |
US20040229245A1 (en) * | 2003-01-06 | 2004-11-18 | Anton Bittner | Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology |
US20040242529A1 (en) * | 1997-04-18 | 2004-12-02 | Geron Corporation | Vector encoding inactivated telomerase for treating cancer |
US20040248093A1 (en) * | 2000-11-27 | 2004-12-09 | Coombs James Howard | Magneto-optical bio-discs and systems including related methods |
US20040247613A1 (en) * | 1997-04-18 | 2004-12-09 | Geron Corporation | Treating cancer using a telomerase vaccine |
US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
US20040259113A1 (en) * | 1993-07-22 | 2004-12-23 | Mayo Foundation For Medical Education And Research, Hybritech Incorporated | Method for detection of metastatic prostate cancer |
US20050003147A1 (en) * | 2003-03-24 | 2005-01-06 | Anderson-Tully Engineered Wood Llc | Laminated board and methods of producing the same |
US20050003496A1 (en) * | 1996-01-23 | 2005-01-06 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20050009031A1 (en) * | 2001-10-25 | 2005-01-13 | Becker Kenneth David | Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases |
US20050013825A1 (en) * | 1997-04-18 | 2005-01-20 | Geron Corporation | Vaccine containing the catalytic subunit of telomerase for treating cancer |
US20050032126A1 (en) * | 2003-03-03 | 2005-02-10 | Coombs James H. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
WO2005016282A2 (en) | 2003-08-14 | 2005-02-24 | Exelixis, Inc. | Prkcs as modifiers of the beta catenin pathway and methods of use |
WO2005019409A2 (en) | 2002-07-15 | 2005-03-03 | Board Of Regents, The University Of Texas System | Combinatorial protein library screening by periplasmic expression |
US20050064479A1 (en) * | 2003-08-12 | 2005-03-24 | Affymetrix, Inc. | Compounds and methods for post incorporation labeling of nucleic acids |
US6872537B1 (en) | 1998-04-14 | 2005-03-29 | Regents Of The University Of California | Assays for the detection of microtubule depolymerization inhibitors |
WO2005048771A1 (en) | 2003-11-18 | 2005-06-02 | Atsushi Takahashi | Resin twisting brush |
WO2005058864A1 (en) | 2003-12-15 | 2005-06-30 | Dade Behring Inc. | Assay for entactogens |
WO2005061482A1 (en) | 2003-12-15 | 2005-07-07 | Dade Behring Inc. | Ecstasy haptens and immunogens |
US20050158809A1 (en) * | 2002-04-16 | 2005-07-21 | The Regents Of The University Of Califorina | Methods of renal cell carcinoma prognosis and treatment selection with carbonic anhydrase IX |
US6924094B1 (en) | 1996-02-08 | 2005-08-02 | Affymetrix, Inc. | Chip-based species identification and phenotypic characterization of microorganisms |
US20050186646A1 (en) * | 2004-01-26 | 2005-08-25 | Cruz Miguel A. | Rapid assay to detect ADAMTS-13 activity |
US20050191285A1 (en) * | 1993-03-17 | 2005-09-01 | University Of Washington | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US20050196820A1 (en) * | 2004-03-03 | 2005-09-08 | Zweig Stephen E. | Apoenzyme reactivation electrochemical detection method and assay |
US20050214827A1 (en) * | 1996-07-08 | 2005-09-29 | Burstein Technologies, Inc. | Assay device and method |
US6958214B2 (en) | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
US20050249789A1 (en) * | 1997-11-20 | 2005-11-10 | Estell David A | Alpha/beta hydrolase-fold enzymes |
US6965020B2 (en) | 1996-01-23 | 2005-11-15 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20050271655A1 (en) * | 2002-08-10 | 2005-12-08 | Biogen Idec Ma Inc. | Nogo receptor antagonists |
WO2005118864A2 (en) | 2004-05-28 | 2005-12-15 | Agensys, Inc. | Antibodies and related molecules that bind to psca proteins |
US20050281916A1 (en) * | 2001-05-18 | 2005-12-22 | Kirsten Bojsen | Method of improving dough and bread quality |
US20050283861A1 (en) * | 2003-06-26 | 2005-12-22 | The J. C. Robinson Seed Co. | Inbred corn line w23129 |
US20050287563A1 (en) * | 1996-01-23 | 2005-12-29 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20050287604A1 (en) * | 2002-05-31 | 2005-12-29 | Bohmer Ralph M | Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood |
US20060008479A1 (en) * | 1996-04-01 | 2006-01-12 | University Of Washington | Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins |
US20060019285A1 (en) * | 2004-06-30 | 2006-01-26 | Joseph Horecka | Analysis of intracellular modifications |
US20060029984A1 (en) * | 2002-05-01 | 2006-02-09 | Jonathan Reeves | PSP94 diagnostic reagents and assays |
US20060035367A1 (en) * | 1997-12-30 | 2006-02-16 | Estell David A | Proteases from gram positive organisms |
US20060035980A1 (en) * | 2003-04-18 | 2006-02-16 | Scanlan Thomas S | Thyronamine derivatives and analogs and methods of use thereof |
US20060040307A1 (en) * | 1997-04-18 | 2006-02-23 | Geron Corporation | Human telomerase catalytic subunit |
US20060046273A1 (en) * | 2004-08-27 | 2006-03-02 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for oral fluid |
WO2006024694A2 (en) | 2004-09-03 | 2006-03-09 | Licentia Oy | Peptide inhibitors of hk2 and their use |
WO2006034048A2 (en) | 2004-09-18 | 2006-03-30 | University Of Maryland, Baltimore | Therapeutic agents targeting the ncca-atp channel and methods of use thereof |
US20060073530A1 (en) * | 2001-08-15 | 2006-04-06 | Olaf Schneewind | Methods and compositions involving sortase B |
US7025961B1 (en) | 1999-03-04 | 2006-04-11 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-plasmodium composition and methods of use |
US20060078951A1 (en) * | 2004-10-08 | 2006-04-13 | Youn Byung S | Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody |
US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
WO2006043178A2 (en) | 2004-10-18 | 2006-04-27 | Danisco A/S | Enzymes |
EP1655381A1 (en) | 2004-11-04 | 2006-05-10 | Affymetrix, Inc. (A US Entity) | Nucleic acid labeling methods |
US20060105354A1 (en) * | 2004-11-18 | 2006-05-18 | Eppendorf Array Technologies S.A. | Real-time quantification of multiple targets on a micro-array |
US7053188B2 (en) | 2002-02-22 | 2006-05-30 | Purdue Research Foundation | Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase |
US7053268B1 (en) | 1999-06-17 | 2006-05-30 | Danisco A/S | Promoter |
US20060134538A1 (en) * | 2004-12-16 | 2006-06-22 | Radu Nora S | Aromatic chalcogen compounds and their use |
US20060140934A1 (en) * | 2004-09-24 | 2006-06-29 | Colin Gegg | Modified Fc molecules |
WO2006072000A2 (en) | 2004-12-29 | 2006-07-06 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositoins and methods related thereto |
US20060153881A1 (en) * | 2000-08-07 | 2006-07-13 | Narum David L | Anti-plasmodium compositions and methods of use |
US7078495B1 (en) | 1999-08-03 | 2006-07-18 | Dade Behring Inc. | Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus |
US7087395B1 (en) | 2001-01-16 | 2006-08-08 | Quest Diagnostics Investments Incorporated | Vitamin D assay |
US20060198817A1 (en) * | 2002-11-26 | 2006-09-07 | Alverdy John C | Materials and methods for preventing and treating microbe-mediated epithelial disorders |
US20060199216A1 (en) * | 2003-09-24 | 2006-09-07 | Intel Corporation | Programmable molecular barcodes |
US7115722B1 (en) | 1997-05-22 | 2006-10-03 | Viventia Biotech, Inc. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
WO2006107962A2 (en) | 2005-04-04 | 2006-10-12 | Biogen Idec Ma Inc | Methods and products for evaluating an immune response to a therapeutic protein |
US20060240496A1 (en) * | 2005-04-21 | 2006-10-26 | Lakshmi Anne | Immunogens, derivatives and immunoassay for ethyl glucuronide |
US20060240498A1 (en) * | 2002-08-13 | 2006-10-26 | Michael Friedman | Devices and methods for detecting amniotic fluid in vaginal secretions |
WO2006116727A2 (en) | 2005-04-27 | 2006-11-02 | Dade Rehring Inc. | Compositions and methods for detection of sirolimus |
EP1728875A2 (en) | 1996-02-08 | 2006-12-06 | Affymetrix, Inc. | Chip-based speciation and phenotypic characterization of microorganisms |
US20060275267A1 (en) * | 1998-03-31 | 2006-12-07 | Morin Gregg B | Nucleic acids encoding inactive variants of human telomerase |
US20060281106A1 (en) * | 1997-10-01 | 2006-12-14 | Andrews William H | Telomerase promoter sequences for screening telomerase modulators |
US20060292570A1 (en) * | 2003-09-04 | 2006-12-28 | Technion Research & Development Foundation Ltd. | Novel synthetic binding pairs and uses thereof |
US20060292579A1 (en) * | 1994-10-21 | 2006-12-28 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface bound double-stranded DNA |
WO2007001991A2 (en) | 2005-06-23 | 2007-01-04 | Dade Behring Inc. | Detection of adulterated samples |
WO2007001986A2 (en) | 2005-06-20 | 2007-01-04 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
US20070026106A1 (en) * | 2003-01-17 | 2007-02-01 | Kreij Arno D | Method |
US20070037187A1 (en) * | 2000-03-24 | 2007-02-15 | Isabelle Alexandre | Identification and quantification of a plurality of biological (micro)organisms or their components |
US20070053840A1 (en) * | 1999-12-23 | 2007-03-08 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
WO2007027714A2 (en) | 2005-08-31 | 2007-03-08 | Schering Corporation | Engineered anti-il-23 antibodies |
EP1762243A1 (en) | 1999-03-31 | 2007-03-14 | Oxford Biomedica (UK) Ltd | Factor for regulation of neurite growth |
US20070059780A1 (en) * | 1998-06-10 | 2007-03-15 | Kent State University | Detection and amplification of ligands |
US20070059717A1 (en) * | 2005-09-15 | 2007-03-15 | Baylor Research Institute | Systemic lupus erythematosus diagnostic assay |
US7192555B2 (en) | 1998-03-30 | 2007-03-20 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
US20070065429A1 (en) * | 2003-04-16 | 2007-03-22 | Biogen Idec Ma Inc. | Nogo-receptor antagonists for the treatment of conditions involving amyloid plaques |
US20070071751A1 (en) * | 1996-09-24 | 2007-03-29 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20070099204A1 (en) * | 2000-03-24 | 2007-05-03 | Isabelle Alexandre | Identification and quantification of a plurality of biological (micro)organisms or their components |
WO2007056352A2 (en) | 2005-11-07 | 2007-05-18 | The Scripps Research Institute | Compositions and methods for controlling tissue factor signaling specificity |
US20070134658A1 (en) * | 2003-03-05 | 2007-06-14 | Genetic Technologies Limited, A.C.N. 009 212 328 | Identification of fetal dna and fetal cell markers in maternal plasma or serum |
US20070134814A1 (en) * | 2005-12-09 | 2007-06-14 | Kajander E O | Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease |
EP1798286A2 (en) | 1997-08-01 | 2007-06-20 | Schering Corporation | Mammalian cell membrane proteins and related reagents |
US20070141570A1 (en) * | 2003-03-07 | 2007-06-21 | Sequenom, Inc. | Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods |
EP1803816A2 (en) | 1996-12-13 | 2007-07-04 | Schering Corporation | Mammalian cell surface antigens; related reagents |
US20070161007A1 (en) * | 2006-01-11 | 2007-07-12 | Wisconsin Alumni Research Foundation | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use |
US20070178462A1 (en) * | 2004-02-18 | 2007-08-02 | Uebele Victor N | Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha1h, encoded proteins and methods of use thereof |
US7252950B1 (en) | 1997-09-04 | 2007-08-07 | The Regents Of The University Of California | Assays for detecting modulators of cytoskeletal function |
WO2007088051A2 (en) | 2006-01-31 | 2007-08-09 | Bayer Schering Pharma Aktiengesellschaft | Modulation of mdl-1 activity for treatment of inflammatory disease |
US20070190534A1 (en) * | 2001-06-11 | 2007-08-16 | Genesis Genomics Inc. | Mitochondrial sites and genes associated with prostate cancer |
WO2007092563A2 (en) | 2006-02-08 | 2007-08-16 | Genzyme Corporation | Gene therapy for niemann-pick disease type a |
DE102006009516A1 (en) * | 2006-02-28 | 2007-08-30 | Analyticon Biotechnologies Ag | Test device for detecting an analyte in a liquid sample comprises a dry porous support with a reaction zone containing an analyte-selective binder, a biomarker/reporter enzyme complex and a reporter substrate |
US20070202515A1 (en) * | 2005-10-12 | 2007-08-30 | Pathologica, Llc. | Promac signature application |
US20070218511A1 (en) * | 1998-03-31 | 2007-09-20 | Genzyme Corporation | Methods for the diagnosis and treatment of lung cancer |
US20070232556A1 (en) * | 2006-03-31 | 2007-10-04 | Montine Thomas J | Methods and compositions for the treatment of neurological diseases and disorders |
WO2007124299A2 (en) | 2006-04-21 | 2007-11-01 | Novartis Ag | Antagonist anti-cd40 antibody pharmaceutical compositions |
US20070264665A1 (en) * | 2006-05-09 | 2007-11-15 | Hashen Akhavan-Tafti | Nonseparation assay methods |
US20070292891A1 (en) * | 2006-06-20 | 2007-12-20 | Wei Tie Q | Tacrolimus standard and methods of using same |
US20070289880A1 (en) * | 2001-09-04 | 2007-12-20 | Zweig Stephen E | Apoenzyme reactivation electrochemical detection method and assay |
US20070298157A1 (en) * | 2004-07-16 | 2007-12-27 | Soe Jorn B | Enzymatic oil-degumming method |
WO2008005429A2 (en) | 2006-07-03 | 2008-01-10 | Charles David Adair | Composition for modulating the expression of cell adhesion molecules |
US7320786B2 (en) | 2000-01-12 | 2008-01-22 | Light Sciences Oncology, Inc. | Photodynamic therapy treatment for eye disease |
WO2008010934A2 (en) | 2006-07-14 | 2008-01-24 | Chemocentryx, Inc. | Triazolyl phenyl benzenesulfonamides |
US20080026394A1 (en) * | 2006-07-11 | 2008-01-31 | Antara Biosciences Inc. | Methods of detecting one or more cancer markers |
US20080044416A1 (en) * | 1999-02-09 | 2008-02-21 | Gang An | Novel, prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
EP1897949A2 (en) | 1998-09-21 | 2008-03-12 | Schering Corporation | Human interleukin-B50. Therapeutic uses |
US20080063783A1 (en) * | 2003-01-17 | 2008-03-13 | Kreij Arno D | Method |
US20080064114A1 (en) * | 2006-09-07 | 2008-03-13 | Institut Pasteur | Genomic morse code |
US20080075322A1 (en) * | 2006-09-13 | 2008-03-27 | Fluidigm Corporation | Methods and systems for determining a baseline during image processing |
US20080075380A1 (en) * | 2006-09-13 | 2008-03-27 | Fluidigm Corporation | Methods and systems for image processing of microfluidic devices |
EP1905832A2 (en) | 1999-09-09 | 2008-04-02 | Schering Corporation | Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions |
EP1908837A2 (en) | 2000-05-25 | 2008-04-09 | Schering Corporation | Human receptor proteins, related reagents and methods |
US20080085526A1 (en) * | 2006-09-08 | 2008-04-10 | United Therapeutics Corporation | Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers |
WO2008043566A2 (en) | 2006-10-11 | 2008-04-17 | Janssen Pharmaceutica N.V. | Compositions and methods for treating and diagnosing irritable bowel syndrome |
WO2008051761A2 (en) | 2006-10-26 | 2008-05-02 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
EP1918377A1 (en) | 2000-05-10 | 2008-05-07 | Schering Corporation | Mammalian cytokine receptor subunit proteins, related reagents and methods |
WO2008067547A2 (en) | 2006-11-30 | 2008-06-05 | Research Development Foundation | Improved immunoglobulin libraries |
US20080129736A1 (en) * | 2006-11-30 | 2008-06-05 | Fluidigm Corporation | Method and apparatus for biological sample analysis |
US20080138346A1 (en) * | 1994-12-07 | 2008-06-12 | Incyte Corporation | Antibodies to a chemokine expressed in inflamed adenoid |
WO2008076321A1 (en) | 2006-12-14 | 2008-06-26 | Schering Corporation | Engineered anti-tslp antibody |
EP1942114A2 (en) | 1999-03-11 | 2008-07-09 | Schering Corporation | Mammalian cytokines; related reagents and methods |
WO2008084410A2 (en) | 2007-01-04 | 2008-07-17 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
EP1947183A1 (en) | 1996-08-16 | 2008-07-23 | Schering Corporation | Mammalian cell surface antigens; related reagents |
DE212006000071U1 (en) | 2005-11-18 | 2008-07-24 | Board of Regents, The University of Texas System, Austin | Quantification of fusion proteins and their activity as a result of chromosomal translocation |
WO2008092164A2 (en) | 2007-01-26 | 2008-07-31 | University Of Louisville Research Foundation, Inc. | Methods of detecting autoantibodies for diagnosing and characterizing disorders |
US20080206188A1 (en) * | 2004-04-20 | 2008-08-28 | Alverdy John C | Therapeutic Delivery System Comprising a High Molecular Weight Peg-Like Compound |
EP1964921A2 (en) | 2000-04-05 | 2008-09-03 | Oscient Pharmaceuticals Corporation | The high bone mass gene of 11q13.3 |
US20080214407A1 (en) * | 2006-10-12 | 2008-09-04 | Eppendorf Array Technologies S.A. | Method and system for quantification of a target compound obtained from a biological sample upon chips |
US20080220498A1 (en) * | 2007-03-06 | 2008-09-11 | Cervin Marguerite A | Variant Buttiauxella sp. phytases having altered properties |
US20080219995A1 (en) * | 2007-02-16 | 2008-09-11 | Konkuk University Industrial Cooperation Corp. | Il-32 monoclonal antibodies and uses thereof |
WO2008110006A1 (en) | 2007-03-12 | 2008-09-18 | Miraculins Inc. | Biomarkers of prostate cancer and uses thereof |
US7432342B2 (en) | 2002-05-03 | 2008-10-07 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof and related documents |
EP1980573A2 (en) | 1997-07-09 | 2008-10-15 | Schering Corporation | Isolated dendritic cell membrane protein genes |
WO2008124670A2 (en) | 2007-04-06 | 2008-10-16 | Becton, Dickinson And Company | Compositions and methods for the identification of a carbapenemase gene |
EP1983001A2 (en) | 1998-09-25 | 2008-10-22 | Schering Corporation | Antibodies to mammalian Langerhans cell antigen and their uses |
US20080267999A1 (en) * | 2001-12-04 | 2008-10-30 | Tainsky Michael A | Neoepitope detection of disease using protein arrays |
EP1988166A1 (en) | 1997-05-07 | 2008-11-05 | Schering Corporation | Human Toll-like receptor proteins, related reagents and methods |
US20080274905A1 (en) * | 2005-09-30 | 2008-11-06 | The Trustees Of Columbia University In The City Of New York | Microfluidic cells with parallel arrays of individual dna molecules |
EP1990057A1 (en) | 2001-05-22 | 2008-11-12 | Merck & Co., Inc. | Beta-secretase substrates and uses thereof |
WO2008137475A2 (en) | 2007-05-01 | 2008-11-13 | Research Development Foundation | Immunoglobulin fc libraries |
US20080287667A1 (en) * | 2001-03-12 | 2008-11-20 | Affymetrix, Inc. | Nucleic Acid Labeling Compounds |
US20080299084A1 (en) * | 2004-08-26 | 2008-12-04 | Engeneic Therapy Pty. Ltd. | Bacterially derived intact minicells that encompass plasma free functional nucleic acid for in vivo delivery to mammalian cells |
US20080305512A1 (en) * | 2006-10-26 | 2008-12-11 | Mattingly Phillip G | Assay for cardiac troponin autoantibodies |
US20090005410A1 (en) * | 2007-06-22 | 2009-01-01 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and n-(2-(hetaryl) hetaryl arylsulfonamides |
US20090023594A1 (en) * | 2006-11-29 | 2009-01-22 | Exiqon A/S | Reagents for labelling nucleic acids and uses thereof |
EP2020239A1 (en) | 2000-04-18 | 2009-02-04 | Schering Corporation | Use of IL-174 agonists for treating infectious diseases |
US20090035784A1 (en) * | 2004-07-30 | 2009-02-05 | Mount Sinai School Of Medicine Of New York University | Npc1l1 and npc1l1 inhibitors and methods of use thereof |
US20090036321A1 (en) * | 2003-06-03 | 2009-02-05 | Chiron Corporation | Methods for predicting the course of a malignant disease |
US20090042209A1 (en) * | 2006-09-01 | 2009-02-12 | Nox Technologies, Inc. | Neoplasia-Specific tNOX Isoforms and Methods |
WO2009021054A2 (en) | 2007-08-06 | 2009-02-12 | Orion Genomics Llc | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene |
EP2026070A1 (en) | 2002-09-09 | 2009-02-18 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
US7495089B2 (en) | 1995-10-23 | 2009-02-24 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
EP2028187A1 (en) | 2000-09-08 | 2009-02-25 | Board Of Regents, The University Of Texas System | Human and mouse targeting peptides identified by phage display |
EP2031070A1 (en) | 2002-12-04 | 2009-03-04 | Applera Corporation | Multiplex amplification of polynucleotides |
US7501509B2 (en) | 2002-06-27 | 2009-03-10 | Health Research, Inc. | Water soluble tetrapyrollic photosensitizers for photodynamic therapy |
WO2009032477A2 (en) | 2007-08-08 | 2009-03-12 | The Board Of Regents Of The University Of Texas System | Vegfr-1/nrp-1 targeting peptides |
EP2042869A2 (en) | 1999-12-06 | 2009-04-01 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
US20090098576A1 (en) * | 2007-10-15 | 2009-04-16 | Idexx Laboratories, Inc. | Feline Pancreatic Lipase |
US20090098249A1 (en) * | 2007-02-07 | 2009-04-16 | Cervin Marguerite A | Variant Buttiauxella sp. Phytases having altered properties |
US20090098245A1 (en) * | 1998-07-21 | 2009-04-16 | Jorn Borch Soe | Foodstuff |
EP2050826A2 (en) | 2007-10-16 | 2009-04-22 | Roche Diagnostics GmbH | Reagents and methods for detecting neisseria gonorrhoeae |
US20090104170A1 (en) * | 2004-11-02 | 2009-04-23 | Richard William Wyatt Childs | Compositions and methods for treating hyperproliferative disorders |
US20090118132A1 (en) * | 2004-11-04 | 2009-05-07 | Roche Molecular Systems, Inc. | Classification of Acute Myeloid Leukemia |
US20090136916A1 (en) * | 2007-08-13 | 2009-05-28 | Trustees Of Tufts College | Methods and microarrays for detecting enteric viruses |
US20090143243A1 (en) * | 2007-08-12 | 2009-06-04 | Gunning Kerry B | Microarray system with improved sequence specificity |
EP2070944A1 (en) | 2001-10-11 | 2009-06-17 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
WO2009079374A1 (en) | 2007-12-14 | 2009-06-25 | Siemens Healthcare Diagnostics Inc. | Methods for detection of hydrophobic drugs |
US20090163407A1 (en) * | 2004-11-15 | 2009-06-25 | Mount Sinai School Of Medicine Of New York University | Compositions and methods for altering wnt autocrine signaling |
US20090170072A1 (en) * | 1999-03-29 | 2009-07-02 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
EP2077277A1 (en) | 2002-02-01 | 2009-07-08 | Schering Corporation | Use of mammalian cytokine; related reagents |
US20090181124A1 (en) * | 2003-12-24 | 2009-07-16 | Danisco A/S | Proteins |
US20090208533A1 (en) * | 2004-08-11 | 2009-08-20 | University Of Georgia Research Foundation, Inc. | Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions |
US20090226387A1 (en) * | 2005-12-23 | 2009-09-10 | Partnership & Corp. Technology Transfer | Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of cellular relaxation |
EP2100959A2 (en) | 1997-07-25 | 2009-09-16 | Schering Corporation | Mammalian cytokine: interleukin-B30 and related reagents |
US20090233946A1 (en) * | 2007-07-12 | 2009-09-17 | Antoni Krasinski | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as ccr2 modulators for the treatment of inflammation |
US20090246800A1 (en) * | 2006-10-26 | 2009-10-01 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
EP2107125A1 (en) | 2008-03-31 | 2009-10-07 | Eppendorf Array Technologies SA (EAT) | Real-time PCR of targets on a micro-array |
US20090269780A1 (en) * | 2008-04-23 | 2009-10-29 | Luminex Corporation | Method for Creating a Standard for Multiple Analytes Found in a Starting Material of Biological Origin |
WO2009132124A2 (en) | 2008-04-24 | 2009-10-29 | The Trustees Of Columbia University In The City Of New York | Geometric patterns and lipid bilayers for dna molecule organization and uses thereof |
EP2119771A2 (en) | 2003-12-24 | 2009-11-18 | Danisco A/S | Proteins |
EP2128270A1 (en) | 2003-08-08 | 2009-12-02 | Genenews Inc. | Osteoarthritis biomarkers and uses thereof |
EP2131198A2 (en) | 2001-09-20 | 2009-12-09 | Board of Regents, The University of Texas System | Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays |
US20090311695A1 (en) * | 2008-03-12 | 2009-12-17 | Talat Nasim | Method |
EP2138510A1 (en) | 1999-07-30 | 2009-12-30 | Schering Corporation | Methods of generating antibodies against cytokines |
US20100015651A1 (en) * | 2006-07-11 | 2010-01-21 | Musc Foundation For Research Development | Predicting Heart Failure Following Myocardial Infarction by Protease and Protease Inhibitor Profiling |
EP2149585A1 (en) | 2003-11-04 | 2010-02-03 | Novartis Vaccines and Diagnostics, Inc. | Antagonist anti-CD40 monoclonal antibodies and methods for their use |
US7668658B2 (en) | 1999-10-13 | 2010-02-23 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
US20100047230A1 (en) * | 2005-02-21 | 2010-02-25 | Hellenic Pasteur Institute | Anti her2/neu antibody |
US20100055033A1 (en) * | 2006-04-07 | 2010-03-04 | The Government Of The United States Of America As Represented By The Secretary | Antibody compositions and methods for treatment of neoplastic disease |
US20100062501A1 (en) * | 2003-12-24 | 2010-03-11 | Paul Wassell | Method |
US20100062947A1 (en) * | 2007-01-11 | 2010-03-11 | Erasmus University Medical Center | Circular chromosome conformation capture (4c) |
US20100068135A1 (en) * | 2005-08-08 | 2010-03-18 | Onconon, Llc | Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility |
US20100081169A1 (en) * | 2007-01-25 | 2010-04-01 | Marc Kolkman | Production of a lipid acyltransferase from transformed bacillus licheniformis cells |
US20100080813A1 (en) * | 2008-07-25 | 2010-04-01 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
EP2172478A2 (en) | 1997-02-07 | 2010-04-07 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Activity-dependent neurotrophic factor III (ADNF III) |
EP2177503A1 (en) | 2004-02-20 | 2010-04-21 | UCL Business PLC | Modulators of cannabinoid receptors |
WO2010054328A2 (en) | 2008-11-07 | 2010-05-14 | Research Development Foundation | Compositions and methods for the inhibition of cripto/grp78 complex formation and signaling |
US7732153B2 (en) | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
WO2010065437A1 (en) | 2008-12-03 | 2010-06-10 | Research Development Foundation | Modulation of olfml-3 mediated angiogenesis |
WO2010066252A1 (en) | 2008-12-09 | 2010-06-17 | Dako Denmark A/S | Method for evaluating pre-treatment |
WO2010068757A1 (en) | 2008-12-12 | 2010-06-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions |
EP2202240A1 (en) | 2000-08-18 | 2010-06-30 | Sterix Limited | Compound |
EP2208797A2 (en) | 2004-03-01 | 2010-07-21 | Applied Biosystems, LLC | Methods, compositions and kits for use in polynucleotide amplification |
US20100184084A1 (en) * | 2003-07-08 | 2010-07-22 | Barry Coller | Methods for measuring platelet reactivity of individuals treated with drug eluting stents |
EP2210899A1 (en) | 2004-11-11 | 2010-07-28 | Danisco A/S | pntr transcription factor |
US20100196419A1 (en) * | 2007-05-02 | 2010-08-05 | Compans Richard W | Enhancement of glycoprotein incorporation into virus-like particles |
WO2010093820A2 (en) | 2009-02-11 | 2010-08-19 | Orion Genomics Llc | Combinations of polymorphisms for determining allele-specific expression of igf2 |
WO2010096658A1 (en) | 2009-02-19 | 2010-08-26 | The Cleveland Clinic Foundation | Corin as a marker for heart failure |
US20100216656A1 (en) * | 1994-10-21 | 2010-08-26 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded dna |
US20100215803A1 (en) * | 2007-08-17 | 2010-08-26 | Niels Erik Larsen | Process |
US20100221272A1 (en) * | 2007-06-28 | 2010-09-02 | University Of Saskatchewan | Immunomodulatory compositions and methods for treating disease with modified host defense peptides |
US20100233725A1 (en) * | 2009-03-12 | 2010-09-16 | Siemens Healthcare Diagnostics Inc., A Corporation Of California | Immunoassays employing non-particulate chemiluminescent reagent |
US20100240065A1 (en) * | 2009-03-18 | 2010-09-23 | Boehringer Ingelheim International Gmbh | Prolyl Hydroxylase Compositions and Methods of Use Thereof |
US20100240101A1 (en) * | 2009-03-19 | 2010-09-23 | Massachusetts Institute Of Technology | Parallel Proximity Ligation Event Analysis |
US20100240070A1 (en) * | 2007-11-07 | 2010-09-23 | Beckman Coulter, Inc. | Nonseparation Assay Methods Using Peroxide Generating Enzymes |
US20100255004A1 (en) * | 2007-04-13 | 2010-10-07 | Dana Farber Cancer Institute | Receptor tyrosine kinase profiling |
WO2010115261A1 (en) | 2009-03-27 | 2010-10-14 | Genesis Genomics Inc. | Aberrant mitochondrial dna, associated fusion transcripts and translation products and hybridization probes therefor |
US20100261153A1 (en) * | 2007-04-16 | 2010-10-14 | Scholl David R | Methods For Direct Fluorescent Antibody Virus Detection In Liquids |
EP2243492A1 (en) | 2003-11-04 | 2010-10-27 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-cd40 monoclonal antibodies for treatment of multiple myeloma |
EP2243491A1 (en) | 2003-11-04 | 2010-10-27 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-CD40 monoclonal antibodies for treatment of chronic lymphocytic leukemia |
EP2246444A1 (en) | 2004-09-14 | 2010-11-03 | The Regents of the University of Colorado, A Body Corporate | Method for treatment with bucindolol based on genetic targeting |
WO2010126670A2 (en) | 2009-03-27 | 2010-11-04 | Gojo Industries, Inc. | Compositions and methods for screening and using compounds antagonizing spore-surface interactions |
US20100291602A1 (en) * | 2009-05-14 | 2010-11-18 | University Of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers |
WO2010134035A1 (en) | 2009-05-19 | 2010-11-25 | Danisco A/S | Use |
EP2256203A1 (en) | 2003-11-21 | 2010-12-01 | Schering Corporation | IL-23 and its receptor; related reagents and methods |
EP2258726A1 (en) | 1995-06-14 | 2010-12-08 | The Regents of the University of California | High affinity human antibodies to c-erbB-2 |
WO2010141421A1 (en) | 2009-06-02 | 2010-12-09 | The Board Of Regents Of The University Of Texas System | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases |
EP2261256A2 (en) | 1999-11-24 | 2010-12-15 | Schering Corporation | Methods of inhibiting metastasis |
WO2010150213A1 (en) | 2009-06-25 | 2010-12-29 | Danisco A/S | Protein |
EP2266624A2 (en) | 2002-07-15 | 2010-12-29 | Board of Regents, The University of Texas System | Duramycin peptide binding to anionic phospholipids and aminophospholipids conjugates and their use in treating viral infections |
EP2266405A2 (en) | 2004-03-12 | 2010-12-29 | Danisco A/S | Fungal lipolytic enzymes |
WO2011002834A2 (en) | 2009-07-01 | 2011-01-06 | American Type Culture Collection | Compositions and methods for diagnosis and treatment of type 1 diabetes |
EP2272869A2 (en) | 2001-10-11 | 2011-01-12 | Amgen Inc. | Angiopoietin-2 specific binding agents |
US20110009861A1 (en) * | 2007-01-04 | 2011-01-13 | Music Foundation For Research Development | Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling |
WO2011008780A1 (en) | 2009-07-13 | 2011-01-20 | Accumetrics, Inc. | Apparatus and methods for processing a whole blood sample |
EP2278015A1 (en) | 2003-01-17 | 2011-01-26 | Danisco A/S | Method of producing a carbohydrate ester |
EP2280285A1 (en) | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases |
EP2281841A2 (en) | 2004-12-03 | 2011-02-09 | Schering Corporation | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
WO2011019423A2 (en) | 2009-05-20 | 2011-02-17 | Schering Corporation | Modulation of pilr receptors to treat microbial infections |
EP2292760A2 (en) | 2000-11-10 | 2011-03-09 | Schering Corporation | Mammalian cytokines, receptors, related reagents and methods |
EP2292661A2 (en) | 2003-11-10 | 2011-03-09 | Schering Corporation | Interleukin-10 antibodies |
EP2295978A2 (en) | 1998-03-20 | 2011-03-16 | The Curators Of The University Of Missouri | Early pregnancy diagnosis using PAGs(Pregnancy-associated Glycoproteins) |
US20110065125A1 (en) * | 2003-07-08 | 2011-03-17 | Accumetrics, Inc. | Controlled platelet activation to monitor therapy of adp antagonists |
US20110065649A1 (en) * | 2006-04-27 | 2011-03-17 | Centre National De La Recherche Scientifique (Cnrs) | Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation |
EP2302072A1 (en) | 2004-11-18 | 2011-03-30 | Eppendorf Array Technologies S.A. | Real time-PCR of targets on a micro-array |
EP2301575A1 (en) | 2003-11-04 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for solid tumors expressing the CD40 cell-surface antigen |
WO2011038403A1 (en) | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
WO2011044186A1 (en) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Human single-chain t cell receptors |
WO2011044553A1 (en) | 2009-10-11 | 2011-04-14 | Biogen Idec Ma Inc. | Anti-vla-4 related assays |
EP2312315A1 (en) | 2005-05-18 | 2011-04-20 | Novartis AG | Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component |
EP2319941A2 (en) | 2005-10-21 | 2011-05-11 | GeneNews Inc. | Method and apparatus for correlating levels of biomarker products with disease |
WO2011056688A2 (en) | 2009-10-27 | 2011-05-12 | Caris Life Sciences, Inc. | Molecular profiling for personalized medicine |
US20110117560A1 (en) * | 2009-11-17 | 2011-05-19 | Musc Foundation For Research Development | ASSESSING LEFT VENTRICULAR REMODELING VIA TEMPORAL DETECTION AND MEASUREMENT OF microRNA IN BODY FLUIDS |
WO2011063198A2 (en) | 2009-11-20 | 2011-05-26 | St. Jude Children's Research Hospital | Methods and compositions for modulating the activity of the interleukin-35 receptor complex |
WO2011061657A1 (en) | 2009-11-17 | 2011-05-26 | Danisco A/S | Method |
US20110129818A1 (en) * | 2009-12-02 | 2011-06-02 | Abbott Laboratories | ASSAY FOR CARDIAC TROPONIN-T (cTnT) |
US20110129854A1 (en) * | 2009-12-02 | 2011-06-02 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
EP2330132A1 (en) | 2003-04-04 | 2011-06-08 | Yeda Research and Development Co. Ltd. | Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins |
US20110136141A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
US20110136103A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
EP2336321A1 (en) | 1999-05-13 | 2011-06-22 | Medical Research Council | Ox2 receptor homolog |
EP2338913A1 (en) | 1995-12-18 | 2011-06-29 | The University of Utah Research Foundation | Chromosome 13-linked breast cancer susceptibility gene |
EP2339032A1 (en) | 2005-04-18 | 2011-06-29 | Mitomics Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
WO2011076881A1 (en) | 2009-12-22 | 2011-06-30 | Arabian Gulf University | Mutant ldl receptor gene |
EP2341349A1 (en) | 2000-05-04 | 2011-07-06 | Siemens Healthcare Diagnostics Products GmbH | Methods for detection of multiple analytes |
EP2341346A2 (en) | 2000-10-18 | 2011-07-06 | The Regents of the University of California | Methods of high-throughput screening for internalizing antibodies and metal-chelating liposomes |
EP2341144A1 (en) | 1999-01-11 | 2011-07-06 | Schering Corporation | Interleukin-17 related mammalian cytokines. Polynucleotides encoding them. Uses |
US20110171346A1 (en) * | 2008-04-18 | 2011-07-14 | Spaangner Christiansen Liv | Process |
US20110172113A1 (en) * | 2008-03-28 | 2011-07-14 | Mitomics Inc. | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
WO2011084357A1 (en) | 2009-12-17 | 2011-07-14 | Schering Corporation | Modulation of pilr to treat immune disorders |
US20110184747A1 (en) * | 2006-08-09 | 2011-07-28 | Carmen Bozic | Method for distribution of a drug |
WO2011092700A1 (en) | 2010-01-27 | 2011-08-04 | Yeda Research And Development Co. Ltd. | Antibodies that inhibit metalloproteins |
WO2011094669A1 (en) | 2010-01-29 | 2011-08-04 | Advanced Cell Diagnostics, Inc. | Methods of in situ detection of nucleic acids |
US20110189677A1 (en) * | 2010-02-03 | 2011-08-04 | Massachusetts Institute Of Technology | Methods For Preparing Sequencing Libraries |
WO2011097627A1 (en) | 2010-02-08 | 2011-08-11 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 161p2f10b proteins |
US20110201559A1 (en) * | 2008-05-22 | 2011-08-18 | Centre National De La Recherche Scientifique (Cnrs) | New Optically Pure Compounds for Improved Therapeutic Efficiency |
EP2359832A2 (en) | 2004-09-18 | 2011-08-24 | University of Maryland, Baltimore | Therapeutic agents targeting the NCCA-ATP channel and methods of use thereof |
US20110207664A1 (en) * | 2000-02-25 | 2011-08-25 | Vegenics Pty Limited | Materials and Methods Involving Hybrid Vascular Endothelial Growth Factor DNAs and Proteins |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
EP2364994A1 (en) | 1994-01-05 | 2011-09-14 | Schering Corporation | Purfied primate CTLA-8 antigens and related reagents |
US20110229495A1 (en) * | 2003-07-07 | 2011-09-22 | Wagner David H | Methods for predicting development of auto-immune diseases and treatment of same |
WO2011114251A1 (en) | 2010-03-18 | 2011-09-22 | Danisco A/S | Foodstuff |
US8034553B2 (en) | 2004-06-24 | 2011-10-11 | Kimberly-Clark Worldwide, Inc. | Biomarkers for wound healing |
WO2011127150A2 (en) | 2010-04-06 | 2011-10-13 | Massachusetts Institute Of Technology | Gene-expression profiling with reduced numbers of transcript measurements |
EP2385124A2 (en) | 1999-05-14 | 2011-11-09 | Arbor Vita Corporation | Peptides or peptide analogues for modulating the binding of a PDZ protein and a PL protein |
WO2011140234A1 (en) | 2010-05-07 | 2011-11-10 | Abbott Laboratories | Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor |
WO2011146479A1 (en) | 2010-05-18 | 2011-11-24 | The Texas A&M University System | Method and composition for the diagnosis and monitoring of inflammatory diseases |
EP2395025A1 (en) | 2007-02-28 | 2011-12-14 | Schering Corporation | Engineered Anti-IL-23R Antibodies |
EP2400030A1 (en) | 2004-05-18 | 2011-12-28 | The Board Of Trustees Of The University Of the Leland Stanford Junior University | Detection of protein translocation by beta-galactosidase reporter fragment complementation |
WO2011163340A1 (en) | 2010-06-25 | 2011-12-29 | Siemens Healthcare Diagnostics Inc. | Reduction in false results in assay measurements |
EP2402752A2 (en) | 2006-10-27 | 2012-01-04 | Janssen Pharmaceutica, N.V. | A method for pharmacologically profiling compounds |
WO2012004759A2 (en) | 2010-07-08 | 2012-01-12 | Danisco A/S | Method |
WO2012006056A2 (en) | 2010-06-29 | 2012-01-12 | Oregon Health & Science University | Ccr6 as a biomarker of alzheimer's disease |
EP2407242A1 (en) | 2010-07-13 | 2012-01-18 | Dublin City University | Direct clone analysis and selection technology |
WO2012009627A2 (en) | 2010-07-16 | 2012-01-19 | Vanderbilt University | Low resource processor using surface tension valves for extracting, concentrating and detecting molecular species |
USRE43135E1 (en) | 2001-05-18 | 2012-01-24 | Danisco A/S | Method of improving dough and bread quality |
WO2012012748A2 (en) | 2010-07-23 | 2012-01-26 | Luminex Corporation | Co-coupling to control reactivity of reagents in immunoassays |
WO2012018476A1 (en) | 2010-07-26 | 2012-02-09 | Abbott Laboratories | Antibodies relating to pivka-ii and uses thereof |
WO2012019012A1 (en) | 2010-08-04 | 2012-02-09 | Idexx Laboratories, Inc. | Detection of degradation products of canine nt-probnp |
US8114619B2 (en) | 2006-03-21 | 2012-02-14 | The Johns Hopkins University | Methods for diagnosis and optimizing treatment of multiple sclerosis |
WO2012024416A1 (en) | 2010-08-20 | 2012-02-23 | Siemens Healthcare Diagnostics Inc. | Assay for analytes using multiple receptors |
EP2423333A1 (en) | 2006-08-25 | 2012-02-29 | Oncotherapy Science, Inc. | Prognostic markers and therapeutic targets for lung cancer |
EP2425850A2 (en) | 2005-06-15 | 2012-03-07 | The Regents of The University of California | Bispecific single chain FV antibody molecules and methods of use thereof |
EP2426145A1 (en) | 2007-02-23 | 2012-03-07 | Schering Corporation | Engineered anti-IL-23p19 antibodies |
EP2426199A2 (en) | 2006-10-20 | 2012-03-07 | Danisco US Inc. | Polyol oxidases |
EP2426144A1 (en) | 2007-02-23 | 2012-03-07 | Schering Corporation | Engineered anti-IL-23p19 antibodies |
US8143045B2 (en) | 2004-10-04 | 2012-03-27 | Danisco A/S | Mutant Citrobacter freundii phytase polypeptide |
WO2012040168A2 (en) | 2010-09-20 | 2012-03-29 | Advanced Cell Diagnostics, Inc. | Biomarkers for differentiating melanoma from benign nevus in the skin |
WO2012047724A1 (en) | 2010-09-29 | 2012-04-12 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
EP2441520A1 (en) | 2010-10-12 | 2012-04-18 | Eppendorf AG | Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay |
EP2444099A1 (en) | 2005-03-31 | 2012-04-25 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
WO2012054795A1 (en) | 2010-10-21 | 2012-04-26 | Advanced Cell Diagnostics, Inc. | An ultra sensitive method for in situ detection of nucleic acids |
EP2450456A2 (en) | 2006-11-02 | 2012-05-09 | Yale University | Assessment of oocyte competence |
WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
CN102507917A (en) * | 2011-11-01 | 2012-06-20 | 四川金域医学检验中心有限公司 | Valproic acid homogeneous-phase enzyme immunity rapid detection kit |
WO2012099896A2 (en) | 2011-01-17 | 2012-07-26 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
WO2012103414A2 (en) | 2011-01-28 | 2012-08-02 | Advanced Cell Diagnostics, Inc. | Rnascope® hpv assay for determining hpv status in head and neck cancers and cervical lesions |
WO2012109133A1 (en) | 2011-02-07 | 2012-08-16 | Research Development Foundation | Engineered immunoglobulin fc polypeptides |
WO2012120377A2 (en) | 2011-03-08 | 2012-09-13 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
WO2012125582A1 (en) | 2011-03-11 | 2012-09-20 | Board Of Regents Of The University Of Nebraska | Biomarker for coronary artery disease |
WO2012131594A1 (en) | 2011-03-28 | 2012-10-04 | Novartis Ag | Markers associated with cyclin-dependent kinase inhibitors |
EP2508596A2 (en) | 2002-02-21 | 2012-10-10 | Bayer Healthcare | MN/CA IX-specific monoclonal antibodies generated from MN/CA IX-deficient mice and methods of use |
WO2012137147A1 (en) | 2011-04-08 | 2012-10-11 | Danisco Us, Inc. | Compositions |
WO2012138941A1 (en) | 2011-04-05 | 2012-10-11 | Longevity Biotech, Inc. | Compositions comprising glucagon analogs and methods of making and using the same |
EP2511708A1 (en) | 2007-10-05 | 2012-10-17 | Affymetrix, Inc. | Highly multiplexed particle-based assays |
EP2520669A2 (en) | 2005-02-07 | 2012-11-07 | GeneNews Inc. | Mild osteoathritis biomarkers and uses thereof |
WO2012150959A1 (en) | 2011-05-04 | 2012-11-08 | Abbott Laboratories | Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor |
EP2526968A2 (en) | 2006-01-27 | 2012-11-28 | Biogen Idec MA Inc. | Nogo receptor antagonists |
WO2012162179A1 (en) | 2011-05-20 | 2012-11-29 | Oligomerix, Inc. | Tau protease compositions and methods of use |
EP2532746A2 (en) | 2007-03-30 | 2012-12-12 | EnGeneIC Molecular Delivery Pty Ltd. | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
EP2546359A1 (en) | 2005-12-08 | 2013-01-16 | Novartis AG | Effects of inhibitors of FGFR3 on gene transcription |
WO2013010170A1 (en) | 2011-07-14 | 2013-01-17 | Lovell Mark A | Process for detection of alzheimer's disease from a serum sample |
WO2013012924A2 (en) | 2011-07-18 | 2013-01-24 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
WO2013011347A1 (en) | 2011-07-18 | 2013-01-24 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
WO2013022599A1 (en) | 2011-08-05 | 2013-02-14 | Research Development Foundation | Improved methods and compositions for modulation of olfml3 mediated angiogenesis |
WO2013025834A2 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
WO2013025532A2 (en) | 2011-08-12 | 2013-02-21 | Siemens Healthcare Diagnostics Inc. | Detection of sex steroids |
WO2013056377A1 (en) | 2011-10-21 | 2013-04-25 | Augurex Life Sciences Corporation | Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis |
US8445637B2 (en) | 2008-12-05 | 2013-05-21 | Abraxis Bioscience, Llc | SPARC binding peptides and uses thereof |
WO2013101758A1 (en) | 2011-12-29 | 2013-07-04 | Baylor Research Institute | Biomarkers for kawasaki disease |
US8481333B2 (en) | 2011-05-31 | 2013-07-09 | Idexx Laboratories, Inc. | Detection of degradation products of feline NT-proBNP |
WO2013116088A1 (en) | 2012-02-02 | 2013-08-08 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detection of methodone metabolite |
WO2013130811A1 (en) | 2012-02-29 | 2013-09-06 | Chemocentryx, Inc. | Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists |
WO2013133917A1 (en) | 2012-03-07 | 2013-09-12 | Siemens Healthcare Diagnostics Inc. | Sandwich assay for immunosuppressant drugs |
WO2013140247A1 (en) | 2012-03-20 | 2013-09-26 | Humabs Biomed Sa | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
WO2013152295A1 (en) | 2012-04-05 | 2013-10-10 | Advanced Cell Diagnostics, Inc. | Detection of immunoglobulin light chain restrication by rna in situ hybridization |
WO2013163035A1 (en) | 2012-04-23 | 2013-10-31 | Uhl Ii, Llc | Devices and methods for detecting analyte in bodily fluid |
WO2013162751A1 (en) | 2012-04-26 | 2013-10-31 | University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
WO2013170168A1 (en) | 2012-05-10 | 2013-11-14 | Bioatla Llc | Multi-specific monoclonal antibodies |
WO2013169689A1 (en) | 2012-05-07 | 2013-11-14 | Siemens Healthcare Diagnostics Inc. | Determination of total analyte concentration |
WO2013174003A1 (en) | 2012-05-24 | 2013-11-28 | Mountgate Group Limited | Compositions and methods related to prevention and treatment of rabies infection |
WO2013181530A1 (en) | 2012-06-01 | 2013-12-05 | Icahn School Of Medicine At Mount Sinai | Ceramide levels in the treatment and prevention of infections |
EP2674440A2 (en) | 2005-12-16 | 2013-12-18 | IBC Pharmaceuticals, Inc. | Multivalent immunoglobulin-based bioactive assemblies |
WO2013192616A1 (en) | 2012-06-22 | 2013-12-27 | Htg Molecular Diagnostics, Inc. | Molecular malignancy in melanocytic lesions |
US8617551B2 (en) | 1995-02-17 | 2013-12-31 | Incyte Corporation | Methods of diagnosing pancreatic inflammation by using chemokine PANEC-1 antibodies |
EP2679599A1 (en) | 2008-02-20 | 2014-01-01 | Amgen Inc. | Antibodies directed to Angiopoietin-1 and Angiopoietin-2 and use thereof |
WO2014004444A1 (en) | 2012-06-27 | 2014-01-03 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for liquid mixing assessment |
WO2014011398A1 (en) | 2012-07-09 | 2014-01-16 | Novartis Ag | Biomarkers associated with cdk inhibitors |
WO2014014788A2 (en) | 2012-07-18 | 2014-01-23 | President And Fellows Of Harvard College | Modification of surfaces for simulataneous repellency and targeted binding of desired moieties |
WO2014020502A2 (en) | 2012-07-31 | 2014-02-06 | Novartis Ag | Markers associated with human double minute 2 inhibitors |
EP2712620A1 (en) | 2008-02-07 | 2014-04-02 | Cornell University | Methods for Preventing or Treating Insulin Resistance |
WO2014059442A2 (en) | 2012-10-12 | 2014-04-17 | Arizona Board Agents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
WO2014063097A1 (en) | 2012-10-19 | 2014-04-24 | Danisco Us Inc. | Stabilization of biomimetic membranes |
WO2014062635A1 (en) | 2012-10-19 | 2014-04-24 | Novartis Ag | Markers for acute lymphoblastic leukemia |
WO2014066590A1 (en) | 2012-10-24 | 2014-05-01 | Research Development Foundation | Jam-c antibodies and methods for treatment of cancer |
US8715665B2 (en) | 2007-04-13 | 2014-05-06 | The General Hospital Corporation | Methods for treating cancer resistant to ErbB therapeutics |
WO2014083427A2 (en) | 2012-11-30 | 2014-06-05 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin d |
WO2014088987A1 (en) | 2012-12-04 | 2014-06-12 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of fkbp-binding immunosuppressant drugs |
US8790871B2 (en) | 2006-05-09 | 2014-07-29 | Musc Foundation For Research Development | Detecting diastolic heart failure by protease and protease inhibitor plasma profiling |
US8791232B2 (en) | 2008-04-30 | 2014-07-29 | Dupont Nutrition Biosciences Aps | Proteins |
WO2014121077A2 (en) | 2013-02-01 | 2014-08-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
WO2014126861A1 (en) | 2013-02-13 | 2014-08-21 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
US8828386B2 (en) | 2002-07-25 | 2014-09-09 | Glenveigh Pharmaceuticals, Llc | Method for extending pregnancy by reducing intraventricular hemorrhaging in patients exhibiting at least one symptom of preeclampsia and eclampsia |
EP2774987A1 (en) | 2006-08-17 | 2014-09-10 | Affymetrix, Inc. | Nucleic acid quantitation from tissue slides |
WO2014141038A2 (en) | 2013-03-11 | 2014-09-18 | Irm Llc | Markers associated with wnt inhibitors |
WO2014145718A2 (en) | 2013-03-15 | 2014-09-18 | Longevity Biotech, Inc. | Peptides comprising non-natural amino acids and methods of making and using the same |
WO2014151535A1 (en) | 2013-03-15 | 2014-09-25 | Bayer Healthcare Llc | Gla domains as targeting agents |
WO2014159242A1 (en) | 2013-03-14 | 2014-10-02 | Novartis Ag | Notch 3 mutants and uses thereof |
WO2014159239A2 (en) | 2013-03-14 | 2014-10-02 | Novartis Ag | Antibodies against notch 3 |
US8859467B2 (en) | 2009-07-17 | 2014-10-14 | Bioatla, Llc | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
WO2014168826A1 (en) | 2013-04-12 | 2014-10-16 | Siemens Healthcare Diagnostics Inc. | Assays for analyte homologs |
US8871207B2 (en) | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
WO2014176047A1 (en) | 2013-04-25 | 2014-10-30 | Novartis Ag | Markers for ezh2 inhibitors |
WO2014186402A1 (en) | 2013-05-14 | 2014-11-20 | Siemens Healthcare Diagnostics Inc. | Stabilized liquid formulations containing receptors |
WO2014190040A1 (en) | 2013-05-21 | 2014-11-27 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
WO2014200767A1 (en) | 2013-06-12 | 2014-12-18 | The General Hospital Corporation | Methods, kits, and systems for multiplexed detection of target molecules and uses thereof |
WO2014204814A1 (en) | 2013-06-18 | 2014-12-24 | Dnatrix, Inc. | Treatment of brain cancer with oncolytic adenovirus |
WO2014210540A1 (en) | 2013-06-28 | 2014-12-31 | Baylor Research Institute | Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis |
US8940519B2 (en) | 2009-04-24 | 2015-01-27 | Dupont Nutrition Biosciences Aps | Method of producing a lipolytic enzyme |
WO2015017552A1 (en) | 2013-08-01 | 2015-02-05 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to cd37 proteins |
WO2015061260A1 (en) | 2013-10-24 | 2015-04-30 | Siemens Healthcare Diagnostics Inc. | Assays for macromolecular analytes |
WO2015070009A2 (en) | 2013-11-08 | 2015-05-14 | The Board Of Regents Of The University Of Texas System | Vh4 antibodies against gray matter neuron and astrocyte |
US9040667B2 (en) | 2009-05-01 | 2015-05-26 | Dako Denmark A/S | Antibody cocktail |
WO2015077607A1 (en) | 2013-11-22 | 2015-05-28 | The Board Of Trustees Of The University Of Illinois | Engineered high-affinity human t cell receptors |
WO2015077473A1 (en) | 2013-11-20 | 2015-05-28 | University Of Iowa Research Foundation | Methods and compositions for treating amyloid deposits |
WO2015089172A1 (en) | 2013-12-13 | 2015-06-18 | Siemens Healthcare Diagnostics Inc. | Pretreatment agent in non-agglutination assays |
WO2015094527A1 (en) | 2013-12-19 | 2015-06-25 | Danisco Us Inc. | Use of hydrophobins to increase gas transferin aerobic fermentation processes |
WO2015105888A1 (en) | 2014-01-07 | 2015-07-16 | Bioatla, Llc | Proteins targeting orthologs |
WO2015116753A1 (en) | 2014-01-29 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Antibodies against the muc1-c/extracellular domain (muc1-c/ecd) |
WO2015120273A1 (en) | 2014-02-07 | 2015-08-13 | The General Hospital Corporation | Differential diagnosis of hepatic neoplasms |
WO2015123565A1 (en) | 2014-02-14 | 2015-08-20 | The General Hospital Corporation | Methods for diagnosing igg4-related disease |
WO2015131099A1 (en) | 2014-02-28 | 2015-09-03 | The General Hospital Corporation | Diagnosis of multiple myeloma and lymphoma |
US9125931B2 (en) | 2010-04-06 | 2015-09-08 | Massachusetts Institute Of Technology | Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers |
US9150644B2 (en) | 2011-04-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
EP2933265A2 (en) | 2005-06-03 | 2015-10-21 | Amicus Therapeutics, Inc. | Pharmacological chaperones for treating obesity |
EP2942627A1 (en) | 2014-05-05 | 2015-11-11 | MicroBPlex, Inc. | Media elaborated with newly synthesized antibodies (mensa) from recently proliferated antibody secreting cells (asc) and uses thereof |
WO2015171938A1 (en) | 2014-05-08 | 2015-11-12 | Novodiax, Inc. | Direct immunohistochemistry assay |
EP2944649A1 (en) | 2008-01-10 | 2015-11-18 | Research Development Foundation | Vaccines and diagnostics for the ehrlichioses |
WO2015179435A1 (en) | 2014-05-19 | 2015-11-26 | Bayer Healthcare Llc | Optimized humanized monoclonal antibodies against activated protein c and uses thereof |
US9212258B2 (en) | 2011-02-23 | 2015-12-15 | The Board Of Trustees Of The University Of Illinois | Amphiphilic dendron-coils, micelles thereof and uses |
WO2015200186A1 (en) | 2014-06-27 | 2015-12-30 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin d epimers in vitamin d assays |
WO2015200182A1 (en) | 2014-06-27 | 2015-12-30 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin d epimers |
EP2960250A1 (en) | 2008-07-16 | 2015-12-30 | Institute for Research in Biomedicine | Human cytomegalovirus neutralising antibodies and use thereof |
US9238843B2 (en) | 2010-12-27 | 2016-01-19 | Eli Lilly And Company | Compositions and methods for identifying and differentiating viral components of multivalent shipping fever vaccines |
US9260517B2 (en) | 2009-11-17 | 2016-02-16 | Musc Foundation For Research Development | Human monoclonal antibodies to human nucleolin |
US9273349B2 (en) | 2013-03-14 | 2016-03-01 | Affymetrix, Inc. | Detection of nucleic acids |
WO2016038550A1 (en) | 2014-09-11 | 2016-03-17 | Novartis Ag | Inhibition of prmt5 to treat mtap-deficiency-related diseases |
WO2016044234A1 (en) | 2014-09-16 | 2016-03-24 | Eric Tsao | Anti-egfr antibody and uses of same |
WO2016055950A1 (en) | 2014-10-08 | 2016-04-14 | Novartis Ag | Combination of human cytomegalovirus neutralizing antibodies |
WO2016057424A1 (en) | 2014-10-06 | 2016-04-14 | Chemocentryx, Inc. | Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies |
US9316641B2 (en) | 2010-01-11 | 2016-04-19 | Biogen Ma Inc. | Assay for JC virus antibodies |
EP3009449A1 (en) | 2008-07-16 | 2016-04-20 | Institute for Research in Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
WO2016061111A1 (en) | 2014-10-13 | 2016-04-21 | Life Technologies Corporation | Methods, kits & compositions for determining gene copy numbers |
WO2016064887A1 (en) | 2014-10-20 | 2016-04-28 | Gen-Probe Incorporated | Red blood cell lysis solution |
WO2016065238A1 (en) | 2014-10-24 | 2016-04-28 | Danisco Us Inc. | Method for producing alcohol by use of a tripeptidyl peptidase |
WO2016062855A1 (en) | 2014-10-24 | 2016-04-28 | Dupont Nutrition Biosciences Aps | Proline tolerant tripeptidyl peptidases and uses thereof |
WO2016075546A2 (en) | 2014-11-14 | 2016-05-19 | Antonio Lanzavecchia | Antibodies that neutralize ebola virus and uses thereof |
EP3023438A1 (en) | 2009-09-03 | 2016-05-25 | Merck Sharp & Dohme Corp. | Anti-gitr antibodies |
WO2016089883A1 (en) | 2014-12-01 | 2016-06-09 | Novartis Ag | Compositions and methods for diagnosis and treatment of prostate cancer |
WO2016100116A1 (en) | 2014-12-17 | 2016-06-23 | Siemens Healthcare Diagnostics Inc. | Sandwich assay design for small molecules |
US9395369B2 (en) | 2012-10-19 | 2016-07-19 | Regents Of The University Of Minnesota | Guinea pig cytomegalovirus (CIDMTR strain) |
US9411930B2 (en) | 2013-02-01 | 2016-08-09 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
WO2016130516A1 (en) | 2015-02-09 | 2016-08-18 | Research Development Foundation | Engineered immunoglobulin fc polypeptides displaying improved complement activation |
WO2016138312A2 (en) | 2015-02-25 | 2016-09-01 | Vanderbilt University | Antibody-mediated neutralization of marburg virus |
US9434985B2 (en) | 2008-09-25 | 2016-09-06 | University Of Massachusetts | Methods of identifying interactions between genomic loci |
WO2016145099A1 (en) | 2015-03-09 | 2016-09-15 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to flt3 proteins |
WO2016145409A1 (en) | 2015-03-11 | 2016-09-15 | The Broad Institute, Inc. | Genotype and phenotype coupling |
US9447454B2 (en) | 2003-10-23 | 2016-09-20 | The Rockefeller University | Method of purifying RNA binding protein-RNA complexes |
US9447467B2 (en) | 2009-04-21 | 2016-09-20 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
WO2016160618A2 (en) | 2015-03-27 | 2016-10-06 | University Of Southern California | Car t-cell therapy directed to lhr for the treatment of solid tumors |
US9476884B2 (en) | 2013-10-04 | 2016-10-25 | University Of Massachusetts | Hybridization- independent labeling of repetitive DNA sequence in human chromosomes |
US9487559B2 (en) | 2010-10-04 | 2016-11-08 | Elro Pharma Sarl | Compositions comprising multivalent synthetic ligands of surface nucleolin and glycosaminoglycans |
EP3091026A1 (en) | 2015-05-08 | 2016-11-09 | Centrillion Technology Holdings Corporation | Disulfide-linked reversible terminators |
WO2016197064A1 (en) | 2015-06-04 | 2016-12-08 | Epstein Alan L | Lym-1 and lym-2 targeted car cell immunotherapy |
EP3103451A1 (en) | 2007-01-12 | 2016-12-14 | University of Maryland, Baltimore | Targetting ncca-atp channel for organ protection following ischemic episode |
US9522880B2 (en) | 2007-02-16 | 2016-12-20 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
US9528998B2 (en) | 2010-04-16 | 2016-12-27 | Abbott Laboratories | Methods and reagents for diagnosing rheumatoid arthrtis |
WO2016210395A1 (en) | 2015-06-26 | 2016-12-29 | Dupont Nutrition Biosciences Aps | Aminopeptidases for protein hydrlyzates |
WO2016207402A1 (en) | 2015-06-26 | 2016-12-29 | Institute For Research In Biomedicine | Proteins comprising a mutated lair-1 fragment and uses thereof |
WO2017011329A1 (en) | 2015-07-10 | 2017-01-19 | West Virginia University | Markers of stroke and stroke severity |
WO2017024114A1 (en) | 2015-08-06 | 2017-02-09 | President And Fellows Of Harvard College | Improved microbe-binding molecules and uses thereof |
WO2017023929A1 (en) | 2015-08-04 | 2017-02-09 | Cd Diagnostics, Inc. | Methods for detecting adverse local tissue reaction (altr) necrosis |
WO2017033152A1 (en) | 2015-08-25 | 2017-03-02 | Prothena Biosciences Limited | Methods for detecting phosphorylated alpha-synuclein |
WO2017040813A2 (en) | 2015-09-02 | 2017-03-09 | University Of Massachusetts | Detection of gene loci with crispr arrayed repeats and/or polychromatic single guide ribonucleic acids |
WO2017040380A2 (en) | 2015-08-28 | 2017-03-09 | Research Development Foundation | Engineered antibody fc variants |
WO2017044419A1 (en) | 2015-09-08 | 2017-03-16 | University Of Massachusetts | Dnase h activity of neisseria meningitidis cas9 |
US9611315B2 (en) | 2003-12-23 | 2017-04-04 | Arbor Vita Corporation | Antibodies for oncogenic strains of HPV and methods of their use |
WO2017059108A1 (en) | 2015-09-29 | 2017-04-06 | Htg Molecular Diagnostics, Inc. | Methods for subtyping diffuse b-cell lymphoma (dlbcl) |
WO2017062953A1 (en) | 2015-10-10 | 2017-04-13 | Intrexon Corporation | Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12 |
WO2017074703A1 (en) | 2015-10-29 | 2017-05-04 | Siemens Healthcare Diagnostics Inc. | Sandwich assay for small molecules |
WO2017083296A1 (en) | 2015-11-09 | 2017-05-18 | The Children's Hospital Of Philadelphia | Glypican 2 as a cancer marker and therapeutic target |
WO2017096304A1 (en) | 2015-12-04 | 2017-06-08 | Board Of Regents, The University Of Texas System | Slc45a2 peptides for immunotherapy |
WO2017109679A1 (en) | 2015-12-21 | 2017-06-29 | Novartis Ag | Compositions and methods for decreasing tau expression |
WO2017112492A2 (en) | 2015-12-22 | 2017-06-29 | The Regents Of The University Of Colorado, A Body Corporate | Protecting rnas from degradation using engineered viral rnas |
US9715573B2 (en) | 2015-02-17 | 2017-07-25 | Dovetail Genomics, Llc | Nucleic acid sequence assembly |
US9733242B2 (en) | 2012-10-07 | 2017-08-15 | Sevident, Inc. | Devices for capturing analyte |
WO2017147060A1 (en) | 2016-02-25 | 2017-08-31 | Dupont Nutrition Biosciences Aps | Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase |
WO2017147186A1 (en) | 2016-02-22 | 2017-08-31 | Ursure, Inc. | System and method for detecting therapeutic agents to monitor adherence to a treatment regimen |
WO2017165438A1 (en) | 2016-03-25 | 2017-09-28 | Muralidhar Reddy Moola | Combinatorial synthesis and biomarker development |
WO2017173091A1 (en) | 2016-03-30 | 2017-10-05 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination |
WO2017172518A1 (en) | 2016-03-29 | 2017-10-05 | Stcube, Inc. | Dual function antibodies specific to glycosylated pd-l1 and methods of use thereof |
US9796762B2 (en) | 2013-04-10 | 2017-10-24 | 4D Pharma Research Limited | Polypeptide and immune modulation |
WO2017189746A1 (en) | 2016-04-27 | 2017-11-02 | Gen-Probe Incorporated | Blood cell lysis reagent |
WO2017194589A1 (en) | 2016-05-10 | 2017-11-16 | Vib Vzw | Inhibition of tau-mediated early synaptic dysfunction |
WO2017201064A1 (en) | 2016-05-16 | 2017-11-23 | President And Fellows Of Harvard College | Aqueous biomolecule coupling on co2-plasma-activated surfaces |
WO2017214068A1 (en) | 2016-06-05 | 2017-12-14 | Berg Llc | Systems and methods for patient stratification and identification of potential biomarkers |
WO2018011283A1 (en) | 2016-07-13 | 2018-01-18 | Humabs Biomed Sa | Novel antibodies specifically binding to zika virus epitopes and uses thereof |
WO2018015296A1 (en) | 2016-07-20 | 2018-01-25 | Vib Vzw | Therapeutic agents for neurological and psychiatric disorders |
WO2018017673A1 (en) | 2016-07-20 | 2018-01-25 | Stcube, Inc. | Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated pd-l1 |
US9891233B2 (en) | 2013-01-02 | 2018-02-13 | N-Dia, Inc. | Methods for predicting time-to-delivery in pregnant women |
US9910040B2 (en) | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
EP3293269A1 (en) | 2007-08-03 | 2018-03-14 | MUSC Foundation For Research Development | Human monoclonal antibodies and methods for producing the same |
EP3301446A1 (en) | 2009-02-11 | 2018-04-04 | Caris MPI, Inc. | Molecular profiling of tumors |
US9937211B2 (en) | 2011-10-07 | 2018-04-10 | 4D Pharma Research Limited | Composition of Roseburia hominis |
US9958464B2 (en) | 2015-03-03 | 2018-05-01 | Ark Diagnostics, Inc. | Pregabalin immunoassays |
EP3318273A1 (en) | 2011-04-01 | 2018-05-09 | ImmunoGen, Inc. | Methods for increasing efficacy of folr1 cancer therapy |
WO2018085679A1 (en) | 2016-11-04 | 2018-05-11 | Stave James W | Direct detection of microorganisms in patient samples by immunoassay |
US9970929B2 (en) | 2013-01-18 | 2018-05-15 | Ark Diagnostics, Inc. | Voriconazole immunoassays |
WO2018089231A1 (en) | 2016-11-09 | 2018-05-17 | Qiagen Sciences Llc | Photoprotective mixtures as imaging reagents in sequencing-by-synthesis |
WO2018100431A1 (en) | 2016-11-29 | 2018-06-07 | Genomic Vision | Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest |
EP3348575A1 (en) | 2011-08-16 | 2018-07-18 | Emory University | Jaml specific binding agents, antibodies, and uses related thereto |
US10036011B2 (en) | 2016-02-11 | 2018-07-31 | Qiagen Waltham, Inc. | Scavenger compounds for improved sequencing-by-synthesis |
WO2018140606A1 (en) | 2017-01-26 | 2018-08-02 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
EP3361254A1 (en) | 2013-12-18 | 2018-08-15 | Siemens Healthcare Diagnostics Inc. | Detection of endothelial disease |
WO2018163051A1 (en) | 2017-03-06 | 2018-09-13 | Novartis Ag | Methods of treatment of cancer with reduced ubb expression |
US10089437B2 (en) | 2013-02-01 | 2018-10-02 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
US10107826B2 (en) | 2011-05-20 | 2018-10-23 | Abbott Japan Co. Ltd. | Immunoassay methods and reagents for decreasing nonspecific binding |
WO2018193063A2 (en) | 2017-04-19 | 2018-10-25 | Institute For Research In Biomedicine | Novel malaria vaccines and antibodies binding to plasmodium sporozoites |
US10119976B2 (en) | 2013-05-28 | 2018-11-06 | Biogen Ma Inc. | Method of assessing risk of PML |
US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
EP3404116A1 (en) | 2013-03-15 | 2018-11-21 | The University of Chicago | Methods and compositions related to t-cell activity |
WO2018222689A1 (en) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof |
WO2018222685A1 (en) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1 |
WO2018226671A1 (en) | 2017-06-06 | 2018-12-13 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands |
EP3418397A1 (en) | 2012-01-24 | 2018-12-26 | CD Diagnostics, Inc. | System for detecting infection in synovial fluid |
US10172916B2 (en) | 2013-11-15 | 2019-01-08 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of treating heart failure with agonists of hypocretin receptor 2 |
WO2019016772A2 (en) | 2017-07-21 | 2019-01-24 | Novartis Ag | Compositions and methods to treat cancer |
EP3435087A1 (en) | 2010-07-16 | 2019-01-30 | Bioatla LLC | Novel methods of protein evolution |
WO2019046556A1 (en) | 2017-09-01 | 2019-03-07 | East Carolina University | Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response |
WO2019043166A1 (en) | 2017-08-31 | 2019-03-07 | Humabs Biomed Sa | Multispecific antibodies specifically binding to zika virus epitopes and uses thereof |
WO2019042153A1 (en) | 2017-09-01 | 2019-03-07 | 四川科伦博泰生物医药股份有限公司 | Recombinant bispecific antibody |
WO2019050998A1 (en) | 2017-09-05 | 2019-03-14 | GLAdiator Biosciences, Inc. | Method of targeting exosomes |
WO2019071054A1 (en) | 2017-10-04 | 2019-04-11 | The Broad Institute, Inc. | Methods and compositions for altering function and structure of chromatin loops and/or domains |
WO2019094595A2 (en) | 2017-11-09 | 2019-05-16 | Pinteon Therapeutics Inc. | Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies |
US10294292B2 (en) | 2014-07-15 | 2019-05-21 | Medimmune, Llc | Neutralizing anti-influenza B antibodies and uses thereof |
US10308987B2 (en) | 2005-04-18 | 2019-06-04 | Mdna Life Sciences Inc. | 3.4 kb mitochondrial DNA deletion for use in the detection of cancer |
EP3494996A1 (en) | 2012-08-23 | 2019-06-12 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 158p1d7 proteins |
WO2019109864A1 (en) | 2017-12-04 | 2019-06-13 | 厦门万泰凯瑞生物技术有限公司 | Kit and method for quantitative detecting hbsag |
US10322151B2 (en) | 2015-06-15 | 2019-06-18 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
WO2019118721A2 (en) | 2017-12-15 | 2019-06-20 | Syngenta Participations Ag | Non-antibody ligands for detecting target proteins |
US10337050B2 (en) | 2016-02-11 | 2019-07-02 | Qiagen Sciences, Llc | Polyphenolic additives in sequencing by synthesis |
WO2019155041A1 (en) | 2018-02-12 | 2019-08-15 | Vib Vzw | Gβγ COMPLEX ANTIBODIES AND USES THEREOF |
WO2019156758A2 (en) | 2018-01-05 | 2019-08-15 | Vanderbilt University | Antibody-mediated neutralization of chikungunya virus |
US10391128B2 (en) | 2015-11-23 | 2019-08-27 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10391130B2 (en) | 2015-06-15 | 2019-08-27 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10393739B2 (en) | 2013-10-03 | 2019-08-27 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
WO2019165217A1 (en) | 2018-02-22 | 2019-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cd153 and/or cd30 in infection |
WO2019169212A1 (en) | 2018-03-02 | 2019-09-06 | Five Prime Therapeutics, Inc. | B7-h4 antibodies and methods of use thereof |
WO2019182896A1 (en) | 2018-03-23 | 2019-09-26 | Board Of Regents, The University Of Texas System | Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor |
EP3546474A2 (en) | 2013-12-18 | 2019-10-02 | President and Fellows of Harvard College | Crp capture/detection of gram positive bacteria |
US10442854B2 (en) | 2015-06-01 | 2019-10-15 | Medimmune, Llc | Neutralizing anti-influenza binding molecules and uses thereof |
WO2019199643A1 (en) | 2018-04-09 | 2019-10-17 | Bio-Techne Corporation | Methods to further enhance signal amplification for the in situ detection of nucleic acids |
US10456444B2 (en) | 2014-12-23 | 2019-10-29 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
US10457934B2 (en) | 2015-10-19 | 2019-10-29 | Dovetail Genomics, Llc | Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection |
WO2019206095A1 (en) | 2018-04-24 | 2019-10-31 | 安源医药科技(上海)有限公司 | Antibody against tim-3 and application thereof |
WO2019213276A1 (en) | 2018-05-02 | 2019-11-07 | Novartis Ag | Regulators of human pluripotent stem cells and uses thereof |
US10471108B2 (en) | 2015-11-20 | 2019-11-12 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10485830B2 (en) | 2016-12-12 | 2019-11-26 | 4D Pharma Plc | Compositions comprising bacterial strains |
US10494419B2 (en) | 2013-10-02 | 2019-12-03 | Medimmune, Llc | Neutralizing anti-influenza A antibodies and uses thereof |
US10493112B2 (en) | 2015-06-15 | 2019-12-03 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
EP3575311A1 (en) | 2012-03-20 | 2019-12-04 | Biogen MA Inc. | Jcv neutralizing antibodies |
EP3575792A1 (en) | 2011-05-31 | 2019-12-04 | Biogen MA Inc. | Method of assessing risk of pml |
US10500237B2 (en) | 2015-06-15 | 2019-12-10 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
WO2019244107A1 (en) | 2018-06-21 | 2019-12-26 | Daiichi Sankyo Company, Limited | Compositions including cd3 antigen binding fragments and uses thereof |
US10526641B2 (en) | 2014-08-01 | 2020-01-07 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
US10543171B2 (en) | 2013-02-22 | 2020-01-28 | The Board Of Trustees Of The University Of Illinois | Dermal drug delivery using amphiphilic dendron-coil micelles |
US10583158B2 (en) | 2016-03-04 | 2020-03-10 | 4D Pharma Plc | Compositions comprising bacterial strains |
WO2020056077A1 (en) | 2018-09-13 | 2020-03-19 | The Board Of Regents Of The University Of Texas System | Novel lilrb4 antibodies and uses thereof |
WO2020069424A1 (en) | 2018-09-28 | 2020-04-02 | Centrillion Technologies, Inc. | Disulfide-linked reversible terminators |
US10610549B2 (en) | 2016-07-13 | 2020-04-07 | 4D Pharma Plc | Composition comprising bacterial strains |
US10610550B2 (en) | 2015-11-20 | 2020-04-07 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
EP3636664A1 (en) | 2012-07-27 | 2020-04-15 | The Board of Trustees of the University of Illinois | Engineering t-cell receptors |
WO2020081568A1 (en) | 2018-10-15 | 2020-04-23 | University Of Massachusetts | Programmable dna base editing by nme2cas9-deaminase fusion proteins |
WO2020081204A1 (en) | 2018-10-18 | 2020-04-23 | Oklahoma Medical Research Foundation | Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity |
US10633442B2 (en) | 2013-08-21 | 2020-04-28 | Board Of Regents Of The University Of Texas System | Antibodies to connexin 43 (Cx43) hemichannels and methods of use thereof to inhibit Cx43 hemichannel opening |
WO2020082209A1 (en) | 2018-10-22 | 2020-04-30 | 上海吉倍生物技术有限公司 | Anti-cldn128.2 antibody and uses thereof |
WO2020083979A1 (en) | 2018-10-23 | 2020-04-30 | Glycardial Diagnostics, S.L. | Antibodies specific for glycosylated apoj and uses thereof |
US10640762B2 (en) | 2007-07-26 | 2020-05-05 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
US10656164B2 (en) | 2016-12-22 | 2020-05-19 | Qiagen Sciences, Llc | Screening asymptomatic pregnant woman for preterm birth |
WO2020103691A1 (en) | 2018-11-20 | 2020-05-28 | 厦门万泰凯瑞生物技术有限公司 | Specific antibody for amh, and uses thereof |
WO2020113237A1 (en) | 2018-11-30 | 2020-06-04 | Caris Mpi, Inc. | Next-generation molecular profiling |
WO2020113084A1 (en) | 2018-11-28 | 2020-06-04 | Oregon Health & Science University | Therapeutic factor xii antibody |
US10683344B2 (en) | 2015-10-07 | 2020-06-16 | Humabs Biomed Sa | Antibodies that potently neutralize hepatitis B virus and uses thereof |
US10683363B2 (en) | 2012-03-30 | 2020-06-16 | The United States Of America As Represented By The Department Of Veteran Affairs | Targeting intracellular target-binding determinants with intracellular antibodies |
WO2020132091A2 (en) | 2018-12-19 | 2020-06-25 | Humabs Biomed Sa | Antibodies that neutralize hepatitis b virus and uses thereof |
WO2020135201A1 (en) | 2018-12-28 | 2020-07-02 | 四川科伦博泰生物医药股份有限公司 | Antibody and use thereof |
US10717787B1 (en) | 2019-04-03 | 2020-07-21 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
DE112018005145T5 (en) | 2017-09-15 | 2020-07-23 | The Regents Of The University Of California | INHIBITION OF AMINOACYLASE 3 (AA3) IN TREATMENT OF CANCER |
US10736926B2 (en) | 2015-06-15 | 2020-08-11 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10744166B2 (en) | 2015-11-23 | 2020-08-18 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
WO2020168162A1 (en) | 2019-02-15 | 2020-08-20 | Bio-Techne Corporation | Methods for multiplex detection of nucleic acids by in situ hybridization |
US10758540B2 (en) | 2017-10-11 | 2020-09-01 | Chemocentryx, Inc. | Treatment of focal segmental glomerulosclerosis with CCR2 antagonists |
US10768185B2 (en) | 2017-07-20 | 2020-09-08 | Trustees Of Boston University | Tenofovir detection assay |
WO2020185312A2 (en) | 2019-01-25 | 2020-09-17 | President And Fellows Of Harvard College | Compositions and method for synthesizing nucleic acids |
US10792360B1 (en) | 2019-11-21 | 2020-10-06 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies |
WO2020211674A1 (en) | 2019-04-16 | 2020-10-22 | 四川科伦博泰生物医药股份有限公司 | Anti-fxi/fxia antibody and use thereof |
WO2020223576A1 (en) | 2019-04-30 | 2020-11-05 | Chondrial Therapeutics, Inc. | Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy |
US10836774B2 (en) | 2016-11-30 | 2020-11-17 | North Carolina State University | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds |
WO2020236818A1 (en) | 2019-05-20 | 2020-11-26 | Nirvana Sciences Inc. | Narrow emission dyes, compositions comprising same, and methods for making and using same |
WO2020237491A1 (en) | 2019-05-28 | 2020-12-03 | Shanghaitech University | Composition and methods to treat ectodermal dysplasia 2, clouston type |
EP3754027A1 (en) | 2014-12-01 | 2020-12-23 | The Broad Institute, Inc. | Methods for altering or modulating spatial proximity between nucleic acids inside of a cell |
US10877045B2 (en) | 2015-07-21 | 2020-12-29 | Saint Louis University | Compositions and methods for diagnosing and treating endometriosis-related infertility |
WO2020261227A1 (en) | 2019-06-26 | 2020-12-30 | Biorchestra Co., Ltd. | Micellar nanoparticles and uses thereof |
US10889637B2 (en) | 2016-02-26 | 2021-01-12 | The Board Of Regents Of The University Of Texas System | Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies |
WO2021016062A1 (en) | 2019-07-19 | 2021-01-28 | The Children's Hospital Of Philadelphia | Chimeric antigen receptors containing glypican 2 binding domains |
WO2021021605A1 (en) | 2019-07-26 | 2021-02-04 | Vanderbilt University | Human monoclonal antibodies to enterovirus d68 |
US10919904B2 (en) | 2016-08-17 | 2021-02-16 | North Carolina State University | Northern-southern route to synthesis of bacteriochlorins |
WO2021030729A1 (en) | 2019-08-15 | 2021-02-18 | Psychemedics Corporation | Homogeneous enzyme immunoassay for keratinized structures |
US10935555B2 (en) | 2016-12-22 | 2021-03-02 | Qiagen Sciences, Llc | Determining candidate for induction of labor |
WO2021042000A1 (en) | 2019-08-29 | 2021-03-04 | Vir Biotechnology, Inc. | Antibody compositions and methods for treating hepatitis b virus infection |
US10947579B2 (en) | 2016-05-13 | 2021-03-16 | Dovetail Genomics, Llc | Recovering long-range linkage information from preserved samples |
WO2021051390A1 (en) | 2019-09-20 | 2021-03-25 | 上海吉倍生物技术有限公司 | Bcma-targeted antibody and chimeric antigen receptor |
US10960013B2 (en) | 2016-03-04 | 2021-03-30 | East Carolina University | J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders |
WO2021062323A1 (en) | 2019-09-26 | 2021-04-01 | Stcube & Co. | Antibodies specific to glycosylated ctla-4 and methods of use thereof |
WO2021063201A1 (en) | 2019-09-30 | 2021-04-08 | 四川科伦博泰生物医药股份有限公司 | Anti-pd-1 antibody and use thereof |
US10973809B2 (en) | 2016-11-23 | 2021-04-13 | Chemocentryx, Inc. | Method of treating focal segmental glomerulosclerosis |
US10975417B2 (en) | 2016-02-23 | 2021-04-13 | Dovetail Genomics, Llc | Generation of phased read-sets for genome assembly and haplotype phasing |
WO2021072277A1 (en) | 2019-10-09 | 2021-04-15 | Stcube & Co. | Antibodies specific to glycosylated lag3 and methods of use thereof |
US10987387B2 (en) | 2017-05-24 | 2021-04-27 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
US11001872B2 (en) | 2015-09-22 | 2021-05-11 | Shawn Clark | Designing customized protein-specific buffer system |
US11007233B2 (en) | 2017-06-14 | 2021-05-18 | 4D Pharma Research Limited | Compositions comprising a bacterial strain of the genus Megasphera and uses thereof |
US11013773B2 (en) | 2011-07-14 | 2021-05-25 | 4D Pharma Research Limited | Lactic acid bacterial strains |
EP3831404A1 (en) | 2014-11-18 | 2021-06-09 | Humabs Biomed S.A. | Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof |
WO2021110126A1 (en) | 2019-12-04 | 2021-06-10 | 珠海泰诺麦博生物技术有限公司 | Antibody against human cytomegalovirus and use thereof |
WO2021119402A1 (en) | 2019-12-12 | 2021-06-17 | President And Fellows Of Harvard College | Compositions and methods for light-directed biomolecular barcoding |
WO2021115240A1 (en) | 2019-12-13 | 2021-06-17 | 四川科伦博泰生物医药股份有限公司 | Anti-tslp antibody and uses thereof |
WO2021126435A1 (en) | 2019-12-20 | 2021-06-24 | Novarock Biotherapeutics, Ltd. | Anti-interleukin-23 p19 antibodies and methods of use thereof |
EP3842452A1 (en) | 2019-12-26 | 2021-06-30 | Universitat Autònoma de Barcelona | Scaffold proteins and therapeutic nanoconjugates based on nidogen |
WO2021136082A1 (en) | 2020-01-02 | 2021-07-08 | 厦门大学 | Polypeptide encoded by bnlf2b gene in eb virus and detection use thereof |
US11078528B2 (en) | 2015-10-12 | 2021-08-03 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
WO2021156490A2 (en) | 2020-02-06 | 2021-08-12 | Vib Vzw | Corona virus binders |
WO2021163265A1 (en) | 2020-02-11 | 2021-08-19 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov- 2) |
WO2021167908A1 (en) | 2020-02-17 | 2021-08-26 | Board Of Regents, The University Of Texas System | Methods for expansion of tumor infiltrating lymphocytes and use thereof |
WO2021170540A1 (en) | 2020-02-25 | 2021-09-02 | Vib Vzw | Leucine-rich repeat kinase 2 allosteric modulators |
WO2021173674A1 (en) | 2020-02-26 | 2021-09-02 | A2 Biotherapeutics, Inc. | Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof |
US11123378B2 (en) | 2017-05-22 | 2021-09-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11123379B2 (en) | 2017-06-14 | 2021-09-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
WO2021195385A1 (en) | 2020-03-26 | 2021-09-30 | Vanderbilt University | HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2) |
WO2021195418A1 (en) | 2020-03-26 | 2021-09-30 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2) |
WO2021216728A1 (en) | 2020-04-22 | 2021-10-28 | President And Fellows Of Harvard College | Isothermal methods, compositions, kits, and systems for detecting nucleic acids |
US11175584B2 (en) | 2015-03-31 | 2021-11-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for detecting traumatic brain injury |
EP3909983A1 (en) | 2015-12-02 | 2021-11-17 | STCube & Co. Inc. | Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof |
WO2021228141A1 (en) | 2020-05-15 | 2021-11-18 | 四川科伦博泰生物医药股份有限公司 | Antibody drug conjugate, preparation method therefor and use thereof |
EP3925980A1 (en) | 2013-08-30 | 2021-12-22 | ImmunoGen, Inc. | Antibodies and assays for detection of folate receptor 1 |
WO2021262840A1 (en) | 2020-06-24 | 2021-12-30 | Vir Biotechnology, Inc. | Engineered hepatitis b virus neutralizing antibodies and uses thereof |
US11214800B2 (en) | 2015-08-18 | 2022-01-04 | The Broad Institute, Inc. | Methods and compositions for altering function and structure of chromatin loops and/or domains |
US11224620B2 (en) | 2016-07-13 | 2022-01-18 | 4D Pharma Plc | Compositions comprising bacterial strains |
EP3939999A1 (en) | 2020-07-14 | 2022-01-19 | Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) | Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof |
US11231424B2 (en) | 2008-10-24 | 2022-01-25 | Ark Diagnostics, Inc. | Levetiracetam immunoassays |
US11253590B2 (en) | 2015-12-02 | 2022-02-22 | Stsciences, Inc. | Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator) |
EP3961214A1 (en) | 2010-12-31 | 2022-03-02 | BioAtla, Inc. | Comprehensive monoclonal antibody generation |
WO2022047359A1 (en) | 2020-08-31 | 2022-03-03 | Berg Llc | Protein biomarkers for pancreatic cancer |
US11267885B2 (en) | 2017-01-26 | 2022-03-08 | Zlip Holding Limited | CD47 antigen binding unit and uses thereof |
WO2022051591A2 (en) | 2020-09-04 | 2022-03-10 | Novarock Biotherapeutics, Ltd. | Nectin-4 antibodies and uses thereof |
US11287423B2 (en) | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
US11292845B2 (en) | 2006-02-28 | 2022-04-05 | Biogen Ma Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
US11306144B2 (en) | 2017-08-25 | 2022-04-19 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods of use thereof |
EP3992210A1 (en) | 2014-01-13 | 2022-05-04 | Baylor Research Institute | Novel vaccines against hpv and hpv-related diseases |
US11333670B2 (en) | 2006-03-03 | 2022-05-17 | Biogen Ma Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
WO2022108897A1 (en) | 2020-11-20 | 2022-05-27 | Vanderbilt University | Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan |
WO2022120378A1 (en) | 2020-12-04 | 2022-06-09 | University Of Tennessee Research Foundation | Method for diagnosing amyloid diseases |
WO2022143743A1 (en) | 2020-12-31 | 2022-07-07 | 和铂医药(苏州)有限公司 | Human lifr antigen binding protein, preparation method therefor, and application thereof |
EP4036572A1 (en) | 2007-08-06 | 2022-08-03 | Siemens Healthcare Diagnostics Inc. | Methods for detection of immunosuppressant drugs |
WO2022162192A2 (en) | 2021-01-29 | 2022-08-04 | Thelper As | Therapeutic and diagnostic agents and uses thereof |
WO2022164805A1 (en) | 2021-01-26 | 2022-08-04 | Vir Biotechnology, Inc. | Compositions and methods for treating hepatitis b virus infection |
WO2022170971A1 (en) | 2021-02-09 | 2022-08-18 | 苏州宜联生物医药有限公司 | Bioactive substance conjugate, preparation method therefor and use thereof |
WO2022175532A1 (en) | 2021-02-19 | 2022-08-25 | Vib Vzw | Cation-independent mannose-6-phosphate receptor binders |
WO2022183502A1 (en) | 2021-03-05 | 2022-09-09 | 上海吉倍生物技术有限公司 | Anti-cldn6 antibody and use thereof |
WO2022188652A1 (en) | 2021-03-09 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | Ror1 binding protein and use thereof |
WO2022192134A1 (en) | 2021-03-08 | 2022-09-15 | Immunogen, Inc. | Methods for increasing efficacy of immunoconjugates targeting adam9 for the treatment of cancer |
WO2022189558A2 (en) | 2021-03-10 | 2022-09-15 | Mabylon Ag | Antibodies against tdp-43 and methods of using the same |
WO2022216798A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for the prognosis of breast cancer progression |
WO2022216841A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer |
WO2022216846A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer |
WO2022224137A1 (en) | 2021-04-19 | 2022-10-27 | Temple Therapeutics BV | Methods for detecting or treating endometrial and ovarian hyperproliferative disorders |
US11547756B2 (en) | 2016-01-13 | 2023-01-10 | Medimmune, Llc | Method of treating influenza A |
EP4116327A1 (en) | 2017-10-11 | 2023-01-11 | Board Of Regents, The University Of Texas System | Human pd-l1 antibodies and methods of use therefor |
WO2023288046A1 (en) | 2021-07-15 | 2023-01-19 | President And Fellows Of Harvard College | Compositions and methods relating to cells with adhered particles |
WO2023016828A2 (en) | 2021-07-30 | 2023-02-16 | Vib Vzw | Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation |
WO2023081070A1 (en) | 2021-11-02 | 2023-05-11 | University Of Massachusetts | Nme2Cas9 INLAID DOMAIN FUSION PROTEINS |
WO2023089377A2 (en) | 2021-11-19 | 2023-05-25 | Mirobio Limited | Engineered pd-1 antibodies and uses thereof |
WO2023144392A1 (en) | 2022-01-28 | 2023-08-03 | Thelper As | Therapeutic and diagnostic agents and uses thereof |
US11723933B2 (en) | 2014-12-23 | 2023-08-15 | Cj Bioscience, Inc. | Composition of bacteroides thetaiotaomicron for immune modulation |
EP4238988A1 (en) | 2022-03-01 | 2023-09-06 | Consejo Superior De Investigaciones Científicas | Antibodies against sars-cov-2 and uses thereof |
EP4242329A2 (en) | 2014-12-08 | 2023-09-13 | Berg LLC | Use of markers including filamin a in the diagnosis and treatment of prostate cancer |
WO2023187407A1 (en) | 2022-04-01 | 2023-10-05 | Bradcode Limited | Human monoclonal antibodies binding to sars-cov-2 and methods of use thereof |
WO2023192976A1 (en) | 2022-04-01 | 2023-10-05 | Board Of Regents, The University Of Texas System | Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor |
WO2023196937A1 (en) | 2022-04-06 | 2023-10-12 | Larimar Therapeutics, Inc. | Frataxin-sensitive markers for monitoring frataxin replacement therapy |
WO2023196866A1 (en) | 2022-04-06 | 2023-10-12 | Mirobio Limited | Engineered cd200r antibodies and uses thereof |
US11807896B2 (en) | 2015-03-26 | 2023-11-07 | Dovetail Genomics, Llc | Physical linkage preservation in DNA storage |
US11842805B2 (en) | 2019-12-02 | 2023-12-12 | Caris Mpi, Inc. | Pan-cancer platinum response predictor |
WO2023239710A1 (en) | 2022-06-08 | 2023-12-14 | Onkure, Inc. | Benzopyrimidin-4(3h)-ones as pi3k inhibitors |
WO2023239940A1 (en) | 2022-06-10 | 2023-12-14 | Research Development Foundation | Engineered fcriib selective igg1 fc variants and uses thereof |
WO2023240201A1 (en) | 2022-06-08 | 2023-12-14 | Larimar Therapeutics, Inc. | Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome |
US11883391B2 (en) | 2020-03-31 | 2024-01-30 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-IL-23 blocking antibodies |
WO2024028794A1 (en) | 2022-08-02 | 2024-02-08 | Temple Therapeutics BV | Methods for treating endometrial and ovarian hyperproliferative disorders |
WO2024038160A1 (en) | 2022-08-18 | 2024-02-22 | Vib Vzw | Means and methods to modulate neuron excitability |
WO2024040020A1 (en) | 2022-08-15 | 2024-02-22 | Absci Corporation | Quantitative affinity activity specific cell enrichment |
WO2024054469A1 (en) | 2022-09-08 | 2024-03-14 | Onkure, Inc. | Isoquinolones as pi3k inhibitors |
WO2024064002A1 (en) | 2022-09-20 | 2024-03-28 | Onkure, Inc. | Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation |
WO2024064024A1 (en) | 2022-09-19 | 2024-03-28 | Onkure, Inc. | ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer |
WO2024068744A1 (en) | 2022-09-27 | 2024-04-04 | Vib Vzw | Antivirals against human parainfluenza virus |
WO2024081345A1 (en) | 2022-10-14 | 2024-04-18 | Onkure, Inc. | Benzopyrimidin-4(3h)-ones as pi3k inhibitors |
-
1972
- 1972-11-06 US US00304156A patent/US3817837A/en not_active Expired - Lifetime
-
1976
- 1976-09-14 BE BE170633A patent/BE846194Q/en not_active IP Right Cessation
Cited By (1582)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6630328B2 (en) | 1909-07-15 | 2003-10-07 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms |
US4813924A (en) * | 1971-05-20 | 1989-03-21 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system |
US4375414A (en) * | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
US5643732A (en) * | 1971-05-20 | 1997-07-01 | Strahilevitz; Meir | Immunological assay methods |
US5840588A (en) * | 1971-05-20 | 1998-11-24 | Strahilevitz; Meir | Agglutination inhibition assay methods and reagents for psychoactive substances |
US6602502B1 (en) | 1971-05-20 | 2003-08-05 | Meir Strahilevitz | Methods and devices for removing species |
US5677132A (en) * | 1971-05-20 | 1997-10-14 | Strahilevitz; Meir | Immunological assay reagent package |
US3932221A (en) * | 1971-06-09 | 1976-01-13 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Immunological isozyme determination method |
US3879262A (en) * | 1972-05-11 | 1975-04-22 | Akzona Inc | Detection and determination of haptens |
US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
US4012285A (en) * | 1972-12-01 | 1977-03-15 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Analysis of isoenzyme patterns |
US3959078A (en) * | 1973-05-18 | 1976-05-25 | Midwest Research Institute | Enzyme immobilization with a thermochemical-photochemical bifunctional agent |
US4255329A (en) * | 1973-10-02 | 1981-03-10 | Syva Company | Double receptor fluorescent immunoassay |
DE2521523A1 (en) * | 1974-06-28 | 1976-01-15 | Syva Co | LACTAM COMPOUNDS AND CONJUGATES |
DE2605162C2 (en) | 1975-02-20 | 1986-08-28 | Syva Co., Palo Alto, Calif. | Enzyme-linked ligand |
US4043872A (en) * | 1975-02-20 | 1977-08-23 | Syva Company | Polyiodothyronine immunoassay |
DE2660911C2 (en) * | 1975-02-20 | 1986-05-28 | Syva Co., Palo Alto, Calif. | Method for the detection or determination of a ligand |
US4171244A (en) * | 1975-02-20 | 1979-10-16 | Syva Company | Enzyme-bound-polyidothyronine |
US4025501A (en) * | 1975-03-20 | 1977-05-24 | Syva Company | Polypeptide propoxyphene derivatives for immunoassay reagents |
US4629688A (en) * | 1975-04-28 | 1986-12-16 | Miles Laboratories, Inc. | Homogeneous specific binding assay method |
US4230797A (en) * | 1975-04-28 | 1980-10-28 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a coenzyme as label |
DE2618511A1 (en) * | 1975-04-28 | 1976-11-04 | Miles Lab | METHOD OF DETERMINING A LIGAND IN A LIQUID MEDIUM AND MEANS OF IMPLEMENTING IT |
USRE32696E (en) * | 1975-09-04 | 1988-06-14 | Akzona Incorporated | Enzymatic immunological method for determination of antigens and antibodies |
US4642285A (en) * | 1975-09-29 | 1987-02-10 | Diamedix Corporation | Sandwich EIA for antigen |
US4474878A (en) * | 1975-09-29 | 1984-10-02 | Cordis Laboratories, Inc. | Sandwich EIA for antigen associated with hepatitis |
US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
US4069105A (en) * | 1977-03-03 | 1978-01-17 | Syva Company | Lidocaine antigens and antibodies |
FR2384259A1 (en) * | 1977-03-15 | 1978-10-13 | Snam Progetti | COMPOSITION INTENDED FOR THE DETERMINATION OF TRI-IODO THYRONINE AND DIAGNOSIS METHOD USING THIS COMPOSITION |
US4250253A (en) * | 1977-03-15 | 1981-02-10 | Snamprogetti S.P.A. | Composition adapted for the determination of tri-iodo thyronine and diagnosis method employing same |
DE2805961A1 (en) * | 1977-04-15 | 1978-10-19 | Syva Co | THEOPHYLLINE ANTIGENS AND ANTIBODIES AND THEIR USE FOR THE DETERMINATION OF THEOPHYLLINE |
DE2830862A1 (en) * | 1977-07-14 | 1979-02-01 | Syva Co | HOMOGENEOUS, COMPETITIVE ANTIENZYME BINDING TEST AND REAGENT FOR CARRYING OUT THE PROCEDURE |
US4233401A (en) * | 1977-07-14 | 1980-11-11 | Syva Company | Antienzyme homogeneous competitive binding assay |
US4168207A (en) * | 1977-08-03 | 1979-09-18 | Syva Company | TBG assay |
DE2913550A1 (en) * | 1978-04-05 | 1979-10-18 | Syva Co | ANALYTICAL PROCEDURE AND REAGENT FOR THE IMPLEMENTATION OF IT |
US4233402A (en) * | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
WO1979000882A1 (en) * | 1978-04-05 | 1979-11-01 | Syva Co | Macromolecular environment control in specific receptor assays |
US4318980A (en) * | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
US4492751A (en) * | 1978-04-10 | 1985-01-08 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing an enzyme substrate as label |
US4791055A (en) * | 1978-04-10 | 1988-12-13 | Miles Inc. | Homogenous specific binding assay reagent system and labeled conjugates |
US5955262A (en) * | 1978-04-13 | 1999-09-21 | Institut Pasteur | Method of detecting and characterizing a nucleic acid or reactant for the application of this method |
US5876928A (en) * | 1978-04-13 | 1999-03-02 | Institut Pasteur | Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method |
US5605800A (en) * | 1978-04-13 | 1997-02-25 | Institut Pasteur | Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method |
US4235969A (en) * | 1978-05-08 | 1980-11-25 | Syva Company | Procainamide antigen conjugates and antibodies |
US4239852A (en) * | 1978-06-12 | 1980-12-16 | Penicillin Assays, Inc. | Antibiotic detection method |
US4244939A (en) * | 1978-06-12 | 1981-01-13 | Baxter Travenol Laboratories, Inc. | Barbituric acid tracers and their preparation |
US4234681A (en) * | 1978-07-21 | 1980-11-18 | The Regents Of The University Of California | Immobolized light emitting systems |
US4241177A (en) * | 1978-08-28 | 1980-12-23 | Syva Company | Propanolol antigen conjugates and antibodies |
US4239745A (en) * | 1978-11-22 | 1980-12-16 | Penicillin Assays, Inc. | Antibiotic detection method |
WO1980002800A1 (en) * | 1979-06-21 | 1980-12-24 | G Oster | Specific impending ovulation indicator |
WO1981000261A1 (en) * | 1979-07-26 | 1981-02-05 | Syva Co | Charge effects in immunoassays |
DE3049711C2 (en) * | 1979-07-26 | 1994-05-05 | Syva Co | Charge effects in immunoassays |
US4287300A (en) * | 1979-07-26 | 1981-09-01 | Syva Company | Charge effects in enzyme immunoassays |
WO1981001414A1 (en) * | 1979-11-19 | 1981-05-28 | Charles Hospital Dev | An improved method of non homogenous enzyme immunoassay |
US4372745A (en) * | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
US4347312A (en) * | 1980-03-20 | 1982-08-31 | Research Triangle Institute | Detection of antibiotics in milk |
EP0043285A1 (en) * | 1980-07-01 | 1982-01-06 | Dainippon Pharmaceutical Co., Ltd. | Method for determination of valproic acid and reagents therein |
EP0057731A1 (en) * | 1980-07-11 | 1982-08-18 | Syva Company | Valproate derivatives and their conjugates to antigenic materials, antibodies thereto and method for the determination of valproate in physiological fluids |
EP0047455A3 (en) * | 1980-09-02 | 1982-03-24 | Syva Company | Single test compositions for immunoassays and method for their preparation |
EP0047455A2 (en) * | 1980-09-02 | 1982-03-17 | Syva Company | Single test compositions for immunoassays and method for their preparation |
US4785080A (en) * | 1981-03-30 | 1988-11-15 | Baker Instruments Corporation | Labeled analytes |
US4378458A (en) * | 1981-03-30 | 1983-03-29 | Baker Instruments Corporation | Novel chromogenic and/or fluorogenic substrates for monitoring catalytic or enzymatic activity |
EP0061762A2 (en) | 1981-03-30 | 1982-10-06 | Baker Instruments Corporation | Nucleotide-based substrates |
US4378428A (en) * | 1981-03-30 | 1983-03-29 | Baker Instruments Corporation | Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays |
US4608252A (en) * | 1981-04-23 | 1986-08-26 | Syntex (U.S.A.) Inc. | Chloramphenicol derivatives antigens and antibodies |
US4489156A (en) * | 1981-04-23 | 1984-12-18 | Syva Company | Chloramphenicol derivatives |
US4604365A (en) * | 1981-06-02 | 1986-08-05 | Electro-Nucleonics, Inc. | Immunoprecipitation assay |
DE3227474A1 (en) * | 1981-07-24 | 1983-02-10 | Fuji Photo Film Co., Ltd., Minami-Ashigara, Kanagawa | ANALYZING FILM AND ANALYZING METHOD USING THE SAME |
US4489157A (en) * | 1981-09-28 | 1984-12-18 | Syva Company | Chloramphenicol derivatives |
US6414152B1 (en) | 1981-12-11 | 2002-07-02 | University Of Wales College Of Medicine Of Heath Park | Luminescent labelling material and procedures |
US4946958A (en) * | 1981-12-11 | 1990-08-07 | The Welsh National School Of Medicine | Chemiluminescent acridinium labelling compounds |
US5103021A (en) * | 1982-04-02 | 1992-04-07 | Syntex (U.S.A.) Inc. | Acetaminophen analogs, antigens, and antibodies |
US4446233A (en) * | 1982-05-05 | 1984-05-01 | E. I. Du Pont De Nemours And Company | Homogeneous immunoassay using covalent hybrid antibodies |
US4587212A (en) * | 1982-05-26 | 1986-05-06 | Boots-Celltech Diagnostics Limited | Immunoassay |
US4472301A (en) * | 1982-05-27 | 1984-09-18 | Miles Laboratories, Inc. | Propranolol immunogen and antibodies |
US4477576A (en) * | 1982-07-26 | 1984-10-16 | Mex Research Associates | Antigen assay method and kit |
US4606855A (en) * | 1982-07-26 | 1986-08-19 | Mex Research Associates C/O Leon Reimer | Monoclonal antibody to digoxin |
US4495281A (en) * | 1982-10-21 | 1985-01-22 | Miles Laboratories, Inc. | Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives |
EP0110640A3 (en) * | 1982-11-19 | 1985-01-09 | Minnesota Mining And Manufacturing Company | Receptor-based histamine assay |
EP0110640A2 (en) * | 1982-11-19 | 1984-06-13 | Minnesota Mining And Manufacturing Company | Receptor-based histamine assay |
US4716109A (en) * | 1983-01-31 | 1987-12-29 | Boots-Celltech Diagnostics Limited | Immunoassay |
EP0117693A3 (en) * | 1983-02-25 | 1986-10-08 | The Upjohn Company | Enzyme-linked immunoassay, assay kits and pair-binding compounds |
US4614712A (en) * | 1983-02-25 | 1986-09-30 | The Upjohn Company | Immunoassays with luciferase labeled ligands or receptors |
EP0117693A2 (en) * | 1983-02-25 | 1984-09-05 | The Upjohn Company | Enzyme-linked immunoassay, assay kits and pair-binding compounds |
US5089388A (en) * | 1983-04-19 | 1992-02-18 | Syntex (U.S.A.) Inc. | Antibodies for salicylate and their preparation |
EP0126631A1 (en) * | 1983-05-18 | 1984-11-28 | Syntex (U.S.A.) Inc. | Chloramphenicol derivatives, intermediates and processes therefor |
US4550075A (en) * | 1983-06-22 | 1985-10-29 | Kallestad Laboratories, Inc. | Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor |
EP0137678A1 (en) * | 1983-08-29 | 1985-04-17 | Syntex (U.S.A.) Inc. | Ultrasonic enhanced immuno-reactions |
US4560648A (en) * | 1983-09-23 | 1985-12-24 | Syntex (U.S.A.) Inc. | Homogeneous enzyme immunoassay for ferritin |
WO1985001747A1 (en) * | 1983-10-17 | 1985-04-25 | Inomedix, Incorporated | Device for rapid quantitative analysis of a fluid |
US4719176A (en) * | 1983-10-31 | 1988-01-12 | Klotz Irving M | Enzyme-free diagnostic binding reagents |
WO1985004397A1 (en) | 1984-03-23 | 1985-10-10 | Oncogen | Platelet related growth regulator |
US4654311A (en) * | 1984-06-15 | 1987-03-31 | Syntex (U.S.A.) Inc. | Serum pretreatment for digoxin assay |
US4791068A (en) * | 1984-06-22 | 1988-12-13 | Scripps Clinic And Research Foundation | Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators |
AU592324B2 (en) * | 1984-10-29 | 1990-01-11 | Roche Diagnostics Corporation | Mehods for protein binding enzyme complementation assays |
US4708929A (en) * | 1984-10-29 | 1987-11-24 | Microgenics Corporation | Methods for protein binding enzyme complementation assays |
EP0185432A3 (en) * | 1984-12-21 | 1987-01-07 | SCLAVO S.p.A. | Immunoenzymatic method for the determination of analytes, and composition suitable to the purpose |
EP0185432A2 (en) * | 1984-12-21 | 1986-06-25 | SCLAVO S.p.A. | Immunoenzymatic method for the determination of analytes, and composition suitable to the purpose |
EP0201716A2 (en) | 1985-04-08 | 1986-11-20 | Bristol-Myers Squibb Company | Expression of immunologically reactive viral proteins |
US4780409A (en) * | 1985-05-02 | 1988-10-25 | Genetic Systems Corporation | Thermally induced phase separation immunoassay |
EP0204523A2 (en) * | 1985-05-31 | 1986-12-10 | Syntex (U.S.A.) Inc. | Glucose-6-phosphate dehydrogenase conjugates, their preparation and use |
US4847195A (en) * | 1985-05-31 | 1989-07-11 | Syntex (U.S.A.) Inc. | Glucose-6-phosphate dehydrogenase conjugates useful in polyiodothyronine assays |
EP0204523A3 (en) * | 1985-05-31 | 1988-11-23 | Syntex (U.S.A.) Inc. | Glucose-6-phosphate dehydrogenase conjugates, their preparation and use |
US4889800A (en) * | 1985-08-12 | 1989-12-26 | Scripps Clinic And Research Foundation | Synthetic polypeptides and receptor molecules derived therefrom and methods of use |
US4830786A (en) * | 1986-02-27 | 1989-05-16 | Syntex (U.S.A.) Inc. | Squaraine dyes |
US5416214A (en) * | 1986-02-27 | 1995-05-16 | Syntex (U.S.A.) Inc. | Squaraine dyes |
US5329019A (en) * | 1986-02-27 | 1994-07-12 | Syntex (U.S.A.) Inc. | Squaraine dye compounds |
US4721704A (en) * | 1986-05-09 | 1988-01-26 | Peninsula Laboratories, Inc. | Potent synthetic atrial peptide analogs |
US4888276A (en) * | 1986-06-26 | 1989-12-19 | Minnesota Mining And Manufacturing Company | Method and composition for the diagnosis of Lyme disease |
US5260441A (en) * | 1986-07-14 | 1993-11-09 | Abbott Laboratories | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
US4868132A (en) * | 1987-02-03 | 1989-09-19 | Abbott Laboratories | Fluorescence polarization immunoassay for amphetamine/methamphetamine |
US6391980B1 (en) | 1987-05-19 | 2002-05-21 | Aventis Pharmaceuticals Products, Inc. | Activated and conjugated polystyrene substrate |
US6326136B1 (en) | 1988-04-01 | 2001-12-04 | Digene Corporation | Macromolecular conjugate made using unsaturated aldehydes |
US5334513A (en) * | 1988-05-17 | 1994-08-02 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5624809A (en) * | 1988-05-17 | 1997-04-29 | Behringwerke Ag | Device for immunochromatographic analysis |
US5451507A (en) * | 1988-05-17 | 1995-09-19 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5468647A (en) * | 1988-05-17 | 1995-11-21 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5057430A (en) * | 1988-09-15 | 1991-10-15 | Biotronic Systems Corporation | Biochemical sensor responsive to bubbles |
US5328828A (en) * | 1988-12-23 | 1994-07-12 | Syntex (U.S.A.) Inc. | Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine |
US5358690A (en) * | 1989-01-10 | 1994-10-25 | Lamina, Ltd. | Environmental sample collection and membrane testing device |
US5939272A (en) * | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
US5679526A (en) * | 1989-01-10 | 1997-10-21 | Biosite Diagnostics Incorporated | Threshold ligand-receptor assay |
US5073629A (en) * | 1989-01-23 | 1991-12-17 | Abbott Laboratories | Methadone fluorescence polarization immunoassay |
US5807695A (en) * | 1989-03-14 | 1998-09-15 | Board Of Regents Of University Of Nebraska | Metallic cation binding polypeptides and methods therefor |
US5639624A (en) * | 1989-03-14 | 1997-06-17 | Board Of Regents Of The University Of Nebraska | Monoclonal antibodies specific for metallic cations and method therefor |
US5354693A (en) * | 1989-04-10 | 1994-10-11 | Abbott Laboratories | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassy |
US5248791A (en) * | 1989-04-10 | 1993-09-28 | Abbott Laboratories | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay |
US5101015A (en) * | 1989-04-10 | 1992-03-31 | Abbott Laboratories | Reagents for an amphetamine-class fluorescence polarization immunoassay |
US5434052A (en) * | 1989-08-15 | 1995-07-18 | Microgenics Corporation | Complementation assay for drug screening |
EP0421589A2 (en) * | 1989-08-15 | 1991-04-10 | Microgenics Corporation | Drug screening assay |
EP0421589A3 (en) * | 1989-08-15 | 1991-12-18 | Microgenics Corporation | Drug screening assay |
US5358931A (en) * | 1990-01-17 | 1994-10-25 | The Regents Of The University Of California | Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications |
US6297060B1 (en) | 1990-03-12 | 2001-10-02 | Biosite Diagnostics, Inc. | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
US5532138A (en) * | 1990-04-26 | 1996-07-02 | Behringwerke Ag | Method and kits for determining peroxidatively active catalysts |
US5143852A (en) * | 1990-09-14 | 1992-09-01 | Biosite Diagnostics, Inc. | Antibodies to ligand analogues and their utility in ligand-receptor assays |
US5527686A (en) * | 1991-07-29 | 1996-06-18 | Serex, Inc. | Differential binding affinities and dissociation assays based thereon |
US5279937A (en) * | 1992-04-30 | 1994-01-18 | Detechnology Canada | Use of macroglobulins to improve the signal-to-background ratio in affinity binding assays |
US5273885A (en) * | 1992-07-31 | 1993-12-28 | Syntex (U.S.A.) Inc. | Conjugates of monophenyl thyroid analogs useful in assays |
US5518890A (en) * | 1992-11-20 | 1996-05-21 | Mccormick & Company, Inc. | Method and apparatus for the quantitation and separation of contaminants from particulate materials |
US5843634A (en) * | 1993-03-09 | 1998-12-01 | Abbott Laboratories | Genetically engineered enzymes and their conjugates for diagnostic assays |
US7601697B2 (en) | 1993-03-17 | 2009-10-13 | University Of Washington | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US6664370B2 (en) | 1993-03-17 | 2003-12-16 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US20050191285A1 (en) * | 1993-03-17 | 2005-09-01 | University Of Washington | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US5726023A (en) * | 1993-03-17 | 1998-03-10 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US5846538A (en) * | 1993-03-17 | 1998-12-08 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the her-2/neu oncogene is associated |
US6953573B1 (en) | 1993-03-17 | 2005-10-11 | University Of Washington | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
US20040082758A1 (en) * | 1993-03-17 | 2004-04-29 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US5876712A (en) * | 1993-03-17 | 1999-03-02 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US20080076904A1 (en) * | 1993-03-17 | 2008-03-27 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US7655239B2 (en) | 1993-03-17 | 2010-02-02 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US8524491B2 (en) | 1993-03-17 | 2013-09-03 | University Of Washington Through Its Center For Commercialization | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US6075122A (en) * | 1993-03-17 | 2000-06-13 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US5801005A (en) * | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
US7247703B2 (en) | 1993-03-17 | 2007-07-24 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated |
US5879894A (en) * | 1993-03-19 | 1999-03-09 | Chiron Diagnostics Corporation | Long emission wavelength chemiluminescent compounds and their use in test assays |
US6455288B1 (en) | 1993-04-08 | 2002-09-24 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
US6033890A (en) * | 1993-04-08 | 2000-03-07 | Behring Diagnostics Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
US6090567A (en) * | 1993-04-08 | 2000-07-18 | Behringwerke Ag | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
US5516639A (en) * | 1993-07-22 | 1996-05-14 | Mayo Foundation For Medical Education And Research | Antibodies specific for human prostate glandular kallkrein |
US20040259113A1 (en) * | 1993-07-22 | 2004-12-23 | Mayo Foundation For Medical Education And Research, Hybritech Incorporated | Method for detection of metastatic prostate cancer |
US6103237A (en) * | 1993-07-22 | 2000-08-15 | Hybritech Incorporated | Stable variant hK2 polypeptide |
US5684144A (en) * | 1993-07-28 | 1997-11-04 | University Of North Texas | Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof |
US5516647A (en) * | 1993-11-05 | 1996-05-14 | Abbott Laboratories | Compounds useful as alkaline phosphatase inhibitors and therapeutic agents |
EP2364994A1 (en) | 1994-01-05 | 2011-09-14 | Schering Corporation | Purfied primate CTLA-8 antigens and related reagents |
US5710009A (en) * | 1994-02-17 | 1998-01-20 | Serex, Inc. | Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon |
US6319713B1 (en) | 1994-02-17 | 2001-11-20 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6406855B1 (en) | 1994-02-17 | 2002-06-18 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6613514B2 (en) | 1994-02-17 | 2003-09-02 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6355484B1 (en) | 1994-02-17 | 2002-03-12 | Maxygen, Inc. | Methods and compositions for polypeptides engineering |
US5856083A (en) * | 1994-05-06 | 1999-01-05 | Pharmacopeia, Inc. | Lawn assay for compounds that affect enzyme activity or bind to target molecules |
US6093796A (en) * | 1994-05-10 | 2000-07-25 | Mayo Foundation For Medical Education And Research | Recombinant hK2 polypeptide |
US6013471A (en) * | 1994-05-10 | 2000-01-11 | Hybritech Incorporated | DNA encoding hK2 variant polypeptides |
EP0705903A1 (en) | 1994-08-12 | 1996-04-10 | Myriad Genetics, Inc. | In vivo mutations and polymorphisms in the 17q-linked breast and ovarian cancer susceptibility gene |
EP0705902A1 (en) | 1994-08-12 | 1996-04-10 | Myriad Genetics, Inc. | 17q-Linked breast and ovarian cancer susceptibility gene |
EP0699754A1 (en) | 1994-08-12 | 1996-03-06 | Myriad Genetics, Inc. | Method for diagnosing a predisposition for breast and ovarian cancer |
US8236493B2 (en) | 1994-10-21 | 2012-08-07 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
US20060292579A1 (en) * | 1994-10-21 | 2006-12-28 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface bound double-stranded DNA |
US20100216656A1 (en) * | 1994-10-21 | 2010-08-26 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded dna |
US20080138346A1 (en) * | 1994-12-07 | 2008-06-12 | Incyte Corporation | Antibodies to a chemokine expressed in inflamed adenoid |
US8008027B2 (en) | 1994-12-07 | 2011-08-30 | Incyte Corporation | Methods of screening for compounds that modulate the activity of ADEC, a chemokine expressed in inflamed adenoid |
US7708984B2 (en) | 1994-12-07 | 2010-05-04 | Incyte Corporation | Methods of treatment with anitbodies to a chemokine expressed in inflamed adenoid |
US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US8617551B2 (en) | 1995-02-17 | 2013-12-31 | Incyte Corporation | Methods of diagnosing pancreatic inflammation by using chemokine PANEC-1 antibodies |
US9090687B2 (en) | 1995-02-17 | 2015-07-28 | Incyte Corporation | Methods of treating pancreatitis |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
EP2258726A1 (en) | 1995-06-14 | 2010-12-08 | The Regents of the University of California | High affinity human antibodies to c-erbB-2 |
WO1997001097A1 (en) * | 1995-06-22 | 1997-01-09 | Serex, Inc. | Receptor:release ligand (reland) complexes and assays and kits based thereon |
US7867975B2 (en) | 1995-10-23 | 2011-01-11 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
US7495089B2 (en) | 1995-10-23 | 2009-02-24 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
US6946296B2 (en) | 1995-11-30 | 2005-09-20 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
EP0785216A1 (en) | 1995-12-18 | 1997-07-23 | Myriad Genetics, Inc. | Chomosome 13-linked breast cancer susceptibility gene BRCA2 |
EP2338913A1 (en) | 1995-12-18 | 2011-06-29 | The University of Utah Research Foundation | Chromosome 13-linked breast cancer susceptibility gene |
US7282327B2 (en) | 1996-01-23 | 2007-10-16 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20050287563A1 (en) * | 1996-01-23 | 2005-12-29 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US7423143B2 (en) | 1996-01-23 | 2008-09-09 | Affymetrix. Inc. | Nucleic acid labeling compounds |
US20030064364A1 (en) * | 1996-01-23 | 2003-04-03 | Lockhart David J. | Nucleic acid analysis techniques |
US20050158772A1 (en) * | 1996-01-23 | 2005-07-21 | Affymetrix, Inc. | Nucleic acid analysis techniques |
US20040101892A1 (en) * | 1996-01-23 | 2004-05-27 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20050003496A1 (en) * | 1996-01-23 | 2005-01-06 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US7291463B2 (en) | 1996-01-23 | 2007-11-06 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US6858711B2 (en) | 1996-01-23 | 2005-02-22 | Affymetrix, Inc. | Labeling reagents |
US20040210045A1 (en) * | 1996-01-23 | 2004-10-21 | Mcgall Glenn | Nucleic acid labeling compounds |
US6965020B2 (en) | 1996-01-23 | 2005-11-15 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20030180757A1 (en) * | 1996-01-23 | 2003-09-25 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US6864059B2 (en) | 1996-01-23 | 2005-03-08 | Affymetrix, Inc. | Biotin containing C-glycoside nucleic acid labeling compounds |
US5808074A (en) * | 1996-02-02 | 1998-09-15 | Georgetown University | Benzoylecgonine conjugate diagnostic reagents |
US20060204970A1 (en) * | 1996-02-08 | 2006-09-14 | Affymetrix, Inc. | Chip-based speciation and phenotypic characterization of microorganisms |
US7252948B2 (en) | 1996-02-08 | 2007-08-07 | Affymetrix, Inc. | Chip-based speciation and phenotypic characterization of microorganisms |
EP1728875A2 (en) | 1996-02-08 | 2006-12-06 | Affymetrix, Inc. | Chip-based speciation and phenotypic characterization of microorganisms |
US6228575B1 (en) | 1996-02-08 | 2001-05-08 | Affymetrix, Inc. | Chip-based species identification and phenotypic characterization of microorganisms |
US6924094B1 (en) | 1996-02-08 | 2005-08-02 | Affymetrix, Inc. | Chip-based species identification and phenotypic characterization of microorganisms |
US5882644A (en) * | 1996-03-22 | 1999-03-16 | Protein Design Labs, Inc. | Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof |
US6129917A (en) * | 1996-03-22 | 2000-10-10 | The University Of Georgia Research Foundation, Inc. | Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods |
US20060008479A1 (en) * | 1996-04-01 | 2006-01-12 | University Of Washington | Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins |
US7166286B2 (en) | 1996-05-22 | 2007-01-23 | Viventia Biotech Inc. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for prophylaxis and detection of cancers |
US6207153B1 (en) | 1996-05-22 | 2001-03-27 | Viventia Biotech, Inc. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
US20040091484A1 (en) * | 1996-05-22 | 2004-05-13 | Dan Michael D. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
US20020106661A1 (en) * | 1996-07-08 | 2002-08-08 | Burstein Laboratories, Inc. | Optical disk-based assay devices and methods |
US6342349B1 (en) | 1996-07-08 | 2002-01-29 | Burstein Technologies, Inc. | Optical disk-based assay devices and methods |
US6331275B1 (en) | 1996-07-08 | 2001-12-18 | Burstein Technologies, Inc. | Spatially addressable, cleavable reflective signal elements, assay device and method |
US20050214827A1 (en) * | 1996-07-08 | 2005-09-29 | Burstein Technologies, Inc. | Assay device and method |
US6312901B2 (en) | 1996-07-08 | 2001-11-06 | Burstein Technologies, Inc. | Spatially addressable, cleavable reflective signal elements, assay device and method |
US6159698A (en) * | 1996-07-18 | 2000-12-12 | Dade Behring Marburg Gmbh | Reagents for assays for mycophenolic acid |
US6171801B1 (en) | 1996-07-18 | 2001-01-09 | Dade Behring Marburg Gmbh | Methods for releasing a ligand from a complex |
US6887669B1 (en) | 1996-07-18 | 2005-05-03 | Dade Behring Marburg Gmbh | Reagents for assays for ligands |
EP1947183A1 (en) | 1996-08-16 | 2008-07-23 | Schering Corporation | Mammalian cell surface antigens; related reagents |
US20070082371A1 (en) * | 1996-09-24 | 2007-04-12 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20070299005A1 (en) * | 1996-09-24 | 2007-12-27 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20070077574A1 (en) * | 1996-09-24 | 2007-04-05 | Tanox, Inc. | family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20070071751A1 (en) * | 1996-09-24 | 2007-03-29 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US7045604B2 (en) | 1996-09-24 | 2006-05-16 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20040039184A1 (en) * | 1996-09-24 | 2004-02-26 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US7576187B2 (en) | 1996-09-24 | 2009-08-18 | Genentech, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US7045596B2 (en) | 1996-09-24 | 2006-05-16 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US6433155B1 (en) | 1996-09-24 | 2002-08-13 | Tanox, Inc. | Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof |
US20030096344A1 (en) * | 1996-10-01 | 2003-05-22 | Cech Thomas R. | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US6927285B2 (en) | 1996-10-01 | 2005-08-09 | Geron Corporation | Genes for human telomerase reverse transcriptase and telomerase variants |
US7585622B1 (en) | 1996-10-01 | 2009-09-08 | Geron Corporation | Increasing the proliferative capacity of cells using telomerase reverse transcriptase |
US7285639B2 (en) | 1996-10-01 | 2007-10-23 | Geron Corporation | Antibody to telomerase reverse transcriptase |
US20090269739A1 (en) * | 1996-10-01 | 2009-10-29 | Geron Corporation | Kit for detection of telomerase reverse transcriptase nucleic acids |
US6808880B2 (en) | 1996-10-01 | 2004-10-26 | Geron Corporation | Method for detecting polynucleotides encoding telomerase |
US6475789B1 (en) | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US7560437B2 (en) | 1996-10-01 | 2009-07-14 | Geron Corporation | Nucleic acid compositions for eliciting an immune response against telomerase reverse transcriptase |
EP1333094A2 (en) | 1996-10-01 | 2003-08-06 | Geron Corporation | Human telomerase catalytic subunit |
US8222392B2 (en) | 1996-10-01 | 2012-07-17 | Geron Corporation | Kit for detection of telomerase reverse transcriptase nucleic acids |
EP2213740A1 (en) | 1996-10-01 | 2010-08-04 | The Regents of the University of Colorado | Human telomerase catalytic subunit |
US6093809A (en) * | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
US20070190561A1 (en) * | 1996-10-01 | 2007-08-16 | Geron Corporation | Segments of the Human Gene for Telomerase Reverse Transcriptase |
EP1783139A2 (en) | 1996-10-01 | 2007-05-09 | Geron Corporation | Human telomerase catalytic subunit |
US6921664B2 (en) | 1996-10-01 | 2005-07-26 | Regents Of The University Of Colorado | Telomerase |
US7195911B2 (en) | 1996-10-01 | 2007-03-27 | Geron Corporation | Mammalian cells that have increased proliferative capacity |
US6617110B1 (en) | 1996-10-01 | 2003-09-09 | Geron Corporation | Cells immortalized with telomerase reverse transcriptase for use in drug screening |
US7005262B2 (en) | 1996-10-01 | 2006-02-28 | Geron Corporation | Methods for detecting nucleic acids encoding human telomerase reverse transcriptase |
US20030100093A1 (en) * | 1996-10-01 | 2003-05-29 | Cech Thomas R. | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
US7517971B1 (en) | 1996-10-01 | 2009-04-14 | Geron Corporation | Muteins of human telomerase reverse transcriptase lacking telomerase catalytic activity |
US20020187471A1 (en) * | 1996-10-01 | 2002-12-12 | Cech Thomas R. | Novel telomerase |
US7056513B2 (en) | 1996-10-01 | 2006-06-06 | Geron Corporation | Telomerase |
US7879609B2 (en) | 1996-10-01 | 2011-02-01 | Geron Corporation | Regulatory segments of the human gene for telomerase reverse transcriptase |
US6479263B1 (en) | 1996-11-14 | 2002-11-12 | Baylor College Of Medicine | Method for detection of micrometastatic prostate cancer |
EP1995318A1 (en) | 1996-12-13 | 2008-11-26 | Schering Corporation | Mammalian cell surface antigens; related reagents |
EP1803816A2 (en) | 1996-12-13 | 2007-07-04 | Schering Corporation | Mammalian cell surface antigens; related reagents |
EP1995317A1 (en) | 1996-12-13 | 2008-11-26 | Schering Corporation | Mammalian cell surface antigens; related reagents |
US20060166225A1 (en) * | 1996-12-18 | 2006-07-27 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6653072B1 (en) | 1996-12-18 | 2003-11-25 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6455253B1 (en) | 1996-12-18 | 2002-09-24 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6303344B1 (en) | 1996-12-18 | 2001-10-16 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US20060084091A1 (en) * | 1996-12-18 | 2006-04-20 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US6579678B1 (en) | 1996-12-18 | 2003-06-17 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
EP2172478A2 (en) | 1997-02-07 | 2010-04-07 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Activity-dependent neurotrophic factor III (ADNF III) |
US6391854B1 (en) | 1997-04-01 | 2002-05-21 | Calyx Therapeutics, Inc. | Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes |
US20020193310A1 (en) * | 1997-04-01 | 2002-12-19 | Bishwajit Nag | Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes |
US6852695B2 (en) | 1997-04-01 | 2005-02-08 | Theracos, Inc. | Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes |
US6127338A (en) * | 1997-04-01 | 2000-10-03 | Calyx Therapeutics, Inc. | Orally active fraction of momordica charantia, active peptides thereof, and their use in the treatment of diabetes |
US7750121B2 (en) | 1997-04-18 | 2010-07-06 | Geron Corporation | Antibody to telomerase reverse transcriptive |
US20040242529A1 (en) * | 1997-04-18 | 2004-12-02 | Geron Corporation | Vector encoding inactivated telomerase for treating cancer |
US8236774B2 (en) | 1997-04-18 | 2012-08-07 | Geron Corporation | Human telomerase catalytic subunit |
US20060040307A1 (en) * | 1997-04-18 | 2006-02-23 | Geron Corporation | Human telomerase catalytic subunit |
US7622549B2 (en) | 1997-04-18 | 2009-11-24 | Geron Corporation | Human telomerase reverse transcriptase polypeptides |
US8709995B2 (en) | 1997-04-18 | 2014-04-29 | Geron Corporation | Method for eliciting an immune response to human telomerase reverse transcriptase |
US7262288B1 (en) | 1997-04-18 | 2007-08-28 | Geron Corporation | Nucleic acids encoding human telomerase reverse transcriptase and related homologs |
US20080279871A1 (en) * | 1997-04-18 | 2008-11-13 | Geron Corporation | Immunogenic composition |
US7413864B2 (en) | 1997-04-18 | 2008-08-19 | Geron Corporation | Treating cancer using a telomerase vaccine |
US20050013825A1 (en) * | 1997-04-18 | 2005-01-20 | Geron Corporation | Vaccine containing the catalytic subunit of telomerase for treating cancer |
US20040247613A1 (en) * | 1997-04-18 | 2004-12-09 | Geron Corporation | Treating cancer using a telomerase vaccine |
EP1988166A1 (en) | 1997-05-07 | 2008-11-05 | Schering Corporation | Human Toll-like receptor proteins, related reagents and methods |
US6670196B1 (en) | 1997-05-14 | 2003-12-30 | Biosite, Inc. | Rapid evaluation of the ratio of biological molecules |
US20040077026A1 (en) * | 1997-05-14 | 2004-04-22 | Biosite, Inc. | Rapid evaluation of the ratio of biological molecules |
US7202042B2 (en) | 1997-05-14 | 2007-04-10 | Biosite Incorporated | Rapid evaluation of the ratio of biological molecules |
US7115722B1 (en) | 1997-05-22 | 2006-10-03 | Viventia Biotech, Inc. | Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
US6235486B1 (en) | 1997-06-20 | 2001-05-22 | Mayo Foundation For Medical Education & Research | Method for detection of breast cancer |
US20030118593A1 (en) * | 1997-07-08 | 2003-06-26 | Dan Michael D. | Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers |
EP1980573A2 (en) | 1997-07-09 | 2008-10-15 | Schering Corporation | Isolated dendritic cell membrane protein genes |
US6228638B1 (en) | 1997-07-11 | 2001-05-08 | University Of North Texas, Health Science Center At Fort Worth | Escherichia coli CSRB gene and RNA encoded thereby |
US6537815B2 (en) | 1997-07-11 | 2003-03-25 | University Of North Texas, Health Science Center At Fort Worth | Method of altering the expression of csrB to modify the properties of a cell |
US20030190752A1 (en) * | 1997-07-11 | 2003-10-09 | Tony Romeo | Escherichia coli csrB gene, RNA encoded thereby, and methods of use thereof |
US6881562B2 (en) | 1997-07-15 | 2005-04-19 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20040126868A1 (en) * | 1997-07-15 | 2004-07-01 | Estell David A. | Gram-positive microorganisms with an inactivated cysteine protease-3 |
US20050142638A1 (en) * | 1997-07-15 | 2005-06-30 | Estell David A. | Proteases from gram-positive organisms |
US20050214816A1 (en) * | 1997-07-15 | 2005-09-29 | Estell David A | Proteases from gram-positive organisms |
US7329527B2 (en) | 1997-07-15 | 2008-02-12 | Genencor International, Inc. | Serine proteases from gram-positive microorganisms |
US6911333B2 (en) | 1997-07-15 | 2005-06-28 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20030175892A1 (en) * | 1997-07-15 | 2003-09-18 | Estell David A. | Proteases from gram-positive organisms |
US20050101001A1 (en) * | 1997-07-15 | 2005-05-12 | Estell David A. | Proteases from gram-position organisms |
US20050095683A1 (en) * | 1997-07-15 | 2005-05-05 | Estell David A. | Proteases from gram-positive organisms |
US20030158070A1 (en) * | 1997-07-15 | 2003-08-21 | Estell David A. | Proteases from gram-positive organisms |
US7329526B2 (en) | 1997-07-15 | 2008-02-12 | Genencor International, Inc. | Serine proteases from-gram-positive microorganisms |
US7316920B2 (en) | 1997-07-15 | 2008-01-08 | Genencor International, Inc. | Serine proteases from gram-positive microorganisms |
US20040137505A1 (en) * | 1997-07-15 | 2004-07-15 | Estell David A. | Gram-positive microorganisms with an inactivated cysteine protease-2 |
US20030180932A1 (en) * | 1997-07-15 | 2003-09-25 | Estell David A. | Proteases from gram-positive organisms |
US20030157642A1 (en) * | 1997-07-15 | 2003-08-21 | Caldwell Robert M. | Increasing production of proteins in gram-positive microorganisms |
US6849440B2 (en) | 1997-07-15 | 2005-02-01 | Genencor International, Inc. | Proteases from gram-positive organisms |
US6833261B2 (en) | 1997-07-15 | 2004-12-21 | Genencor International, Inc. | Proteases from gram-positive organisms |
US7329525B2 (en) | 1997-07-15 | 2008-02-12 | Genencor International, Inc. | Serine proteases from gram-positive microorganisms |
US6506579B1 (en) | 1997-07-15 | 2003-01-14 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms using SecG |
US6723550B1 (en) | 1997-07-15 | 2004-04-20 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20030166248A1 (en) * | 1997-07-15 | 2003-09-04 | Estell David A. | Proteases from gram-positive organisms |
US7037714B2 (en) | 1997-07-16 | 2006-05-02 | Genencor International, Inc. | Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same |
US20030124676A1 (en) * | 1997-07-16 | 2003-07-03 | Quax Wilhelmus J. | Increasing production of proteins in gram-positive microorganisms |
US6521421B1 (en) | 1997-07-16 | 2003-02-18 | Genencor International, Inc. | Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same |
EP2233574A1 (en) | 1997-07-25 | 2010-09-29 | Schering Corporation | Mammalian cytokine: interleukin-B30 and related reagents |
EP2100959A2 (en) | 1997-07-25 | 2009-09-16 | Schering Corporation | Mammalian cytokine: interleukin-B30 and related reagents |
US6180411B1 (en) | 1997-08-01 | 2001-01-30 | The Regents Of The University Of California | Light-triggered indicators that memorize analyte concentrations |
EP1798287A2 (en) | 1997-08-01 | 2007-06-20 | Schering Corporation | Mammalian cell membrane proteins and related reagents |
EP1798286A2 (en) | 1997-08-01 | 2007-06-20 | Schering Corporation | Mammalian cell membrane proteins and related reagents |
US6489309B1 (en) | 1997-08-08 | 2002-12-03 | Dade Behring Marburg Gmbh | Polysaccharide conjugates of biomolecules |
US20050281833A1 (en) * | 1997-08-08 | 2005-12-22 | Dade Behring Marburg Gmbh | Polysaccharide conjugates of biomolecules |
US5929049A (en) * | 1997-08-08 | 1999-07-27 | Dade Behring Marburg Gmbh | Polysaccharide conjugates of biomolecules |
US6949524B2 (en) | 1997-08-08 | 2005-09-27 | Dade Behring Marburg Gmbh | Polysaccharide conjugates of biomolecules |
US20030204069A1 (en) * | 1997-08-14 | 2003-10-30 | Morin Gregg B. | Segments of the human gene for telomerase reverse transcriptase |
US7199234B2 (en) | 1997-08-14 | 2007-04-03 | Geron Corporation | Regulatory segments of the human gene for telomerase reverse transcriptase |
US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
US7252950B1 (en) | 1997-09-04 | 2007-08-07 | The Regents Of The University Of California | Assays for detecting modulators of cytoskeletal function |
US20080096225A1 (en) * | 1997-09-04 | 2008-04-24 | The Regents Of The University Of California | Assays for detecting modulators of cytoskeletal function |
US7189555B2 (en) | 1997-09-15 | 2007-03-13 | Genecor International, Inc. | Proteases from gram-positive organisms |
US8101563B2 (en) | 1997-09-15 | 2012-01-24 | Danisco Us Inc. | Proteases from gram-positive organisms |
US6905868B2 (en) | 1997-09-15 | 2005-06-14 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20050106668A1 (en) * | 1997-09-15 | 2005-05-19 | Estell David A. | Proteases from gram-positive organisms |
US7326531B2 (en) | 1997-09-15 | 2008-02-05 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20030113895A1 (en) * | 1997-09-15 | 2003-06-19 | Estell David A. | Proteases from gram-positive organisms |
US20050059112A1 (en) * | 1997-09-15 | 2005-03-17 | Estell David A. | Proteases from gram-positive organisms |
US6833265B2 (en) | 1997-09-15 | 2004-12-21 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20020127641A1 (en) * | 1997-09-15 | 2002-09-12 | Estell David A. | Proteases from gram-positive organisms |
US6521440B1 (en) | 1997-09-15 | 2003-02-18 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20050244925A1 (en) * | 1997-09-15 | 2005-11-03 | Estell David A | Proteases from gram-positive organisms |
US7241575B2 (en) | 1997-09-15 | 2007-07-10 | Genecor International, Inc. | Proteases from gram-positive organisms |
US20050009146A1 (en) * | 1997-09-15 | 2005-01-13 | Estell David A. | Proteases from gram-positive organisms |
US7220716B2 (en) | 1997-09-15 | 2007-05-22 | Genencor International, Inc. | Proteases from gram-positive organisms |
US20060281106A1 (en) * | 1997-10-01 | 2006-12-14 | Andrews William H | Telomerase promoter sequences for screening telomerase modulators |
US7378244B2 (en) | 1997-10-01 | 2008-05-27 | Geron Corporation | Telomerase promoters sequences for screening telomerase modulators |
US20080220438A1 (en) * | 1997-10-01 | 2008-09-11 | Geron Corporation | Telomerase Promoter Sequences for Screening Telomerase Modulators |
US20020061580A1 (en) * | 1997-11-20 | 2002-05-23 | Estell David A. | Alpha/beta hydrolase-fold enzymes |
US6458557B1 (en) | 1997-11-20 | 2002-10-01 | Genencor International, Inc. | Enhancing growth in gram-positive microorganisms using formate supplementation and inactivation of formate-associated transport proteins |
US20050249789A1 (en) * | 1997-11-20 | 2005-11-10 | Estell David A | Alpha/beta hydrolase-fold enzymes |
US7033817B2 (en) | 1997-12-30 | 2006-04-25 | Genencor International, Inc. | Proteases from gram positive organisms |
US6794179B2 (en) | 1997-12-30 | 2004-09-21 | Genencor International, Inc. | Proteases from gram positive organisms |
US20050014227A1 (en) * | 1997-12-30 | 2005-01-20 | Estell David A. | Proteases from gram positive organisms |
US6599731B1 (en) | 1997-12-30 | 2003-07-29 | Genencor International, Inc. | Proteases from gram positive organisms |
US20050019888A1 (en) * | 1997-12-30 | 2005-01-27 | Estell David A. | Proteases from gram positive organisms |
US20050019887A1 (en) * | 1997-12-30 | 2005-01-27 | Estell David A. | Proteases from gram positive organisms |
US7070986B2 (en) | 1997-12-30 | 2006-07-04 | Genencor International, Inc. | Proteases from gram positive organisms |
US6872807B2 (en) | 1997-12-30 | 2005-03-29 | Genencor International, Inc. | Proteases from gram positive organisms |
US7070819B2 (en) | 1997-12-30 | 2006-07-04 | Genencor International, Inc. | Proteases from gram positive organisms |
US20030078177A1 (en) * | 1997-12-30 | 2003-04-24 | Estell David A. | Proteases from gram positive organisms |
US20050245417A1 (en) * | 1997-12-30 | 2005-11-03 | Estell David A | Proteases from gram positive organisms |
US7070990B2 (en) | 1997-12-30 | 2006-07-04 | Genencor International, Inc. | Proteases from GRAM positive organisms |
US20060035367A1 (en) * | 1997-12-30 | 2006-02-16 | Estell David A | Proteases from gram positive organisms |
US20050089963A1 (en) * | 1997-12-30 | 2005-04-28 | Estell David A. | Proteases from gram positive organisms |
US7078216B2 (en) | 1997-12-30 | 2006-07-18 | Genencor International, Inc. | Proteases from gram positive organisms |
US20050101504A1 (en) * | 1997-12-30 | 2005-05-12 | Estell David A. | Proteases from gram positive organisms |
US20050014244A1 (en) * | 1997-12-30 | 2005-01-20 | Estell David A. | Proteases from gram positive organisms |
US7078372B2 (en) | 1997-12-30 | 2006-07-18 | Genencor International, Inc. | Proteases from gram positive organisms |
US7098021B2 (en) | 1997-12-30 | 2006-08-29 | Genencor International, Inc. | Proteases from gram positive organisms |
US7569357B2 (en) | 1998-01-20 | 2009-08-04 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
US6759243B2 (en) | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
US6673914B1 (en) | 1998-01-22 | 2004-01-06 | John Wayne Cancer Institute | Human tumor-associated gene |
US6060260A (en) * | 1998-02-27 | 2000-05-09 | Dade Behring Inc. | Methods for reducing adsorption in an assay |
WO1999045124A2 (en) | 1998-03-04 | 1999-09-10 | Genencor International, Inc. | Modified forms of pullulanase |
EP2295978A2 (en) | 1998-03-20 | 2011-03-16 | The Curators Of The University Of Missouri | Early pregnancy diagnosis using PAGs(Pregnancy-associated Glycoproteins) |
US20070116597A1 (en) * | 1998-03-30 | 2007-05-24 | Mink Ronald W | Device for collection and assay of oral fluids |
US7541194B2 (en) | 1998-03-30 | 2009-06-02 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
US7192555B2 (en) | 1998-03-30 | 2007-03-20 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
EP1696236A2 (en) | 1998-03-30 | 2006-08-30 | OraSure Technologies, Inc. | Device for assay of antibodies in oral fluids |
US20020192839A1 (en) * | 1998-03-30 | 2002-12-19 | Epitope, Inc. | Collection device for single step assay of oral fluids |
US20110091892A1 (en) * | 1998-03-31 | 2011-04-21 | Genzyme Corporation | Methods for the Diagnosis and Treatment of Lung Cancer |
US8796438B2 (en) | 1998-03-31 | 2014-08-05 | Geron Corporation | Nucleic acids encoding inactive variants of human telomerase |
US20100062443A1 (en) * | 1998-03-31 | 2010-03-11 | Genzyme Corporation | Methods for the Diagnosis and Treatment of Lung Cancer |
US7846667B2 (en) | 1998-03-31 | 2010-12-07 | Genzyme Corporation | Methods for the diagnosis and treatment of lung cancer |
US20060275267A1 (en) * | 1998-03-31 | 2006-12-07 | Morin Gregg B | Nucleic acids encoding inactive variants of human telomerase |
US20070218511A1 (en) * | 1998-03-31 | 2007-09-20 | Genzyme Corporation | Methods for the diagnosis and treatment of lung cancer |
US8067240B2 (en) | 1998-03-31 | 2011-11-29 | Esoterix Genetic Laboratories, Llc | Methods for the diagnosis and treatment of lung cancer |
US7108968B2 (en) | 1998-04-03 | 2006-09-19 | Affymetrix, Inc. | Mycobacterial rpoB sequences |
US20020187467A1 (en) * | 1998-04-03 | 2002-12-12 | Thomas Gingeras | Mycobacterial rpob sequences |
US20060147964A1 (en) * | 1998-04-03 | 2006-07-06 | Affymetrix, Inc. | Mycobacterial rpoB sequences |
US6699969B1 (en) | 1998-04-14 | 2004-03-02 | The Regents Of The University Of California | Assays for the detection of microtubule depolymerization inhibitors |
US6410687B1 (en) | 1998-04-14 | 2002-06-25 | The Regents Of The University Of California | Polypeptides for the detection of microtubule depolymerization inhibitors |
US6429304B1 (en) | 1998-04-14 | 2002-08-06 | The Regents Of The University Of California | Nucleic acids encoding a katanin p60 subunit |
US6872537B1 (en) | 1998-04-14 | 2005-03-29 | Regents Of The University Of California | Assays for the detection of microtubule depolymerization inhibitors |
US6153442A (en) * | 1998-05-20 | 2000-11-28 | Dade Behring Inc. | Reagents and methods for specific binding assays |
US6303325B1 (en) | 1998-05-29 | 2001-10-16 | Dade Behring Inc. | Method for detecting analytes |
WO1999064447A1 (en) * | 1998-06-09 | 1999-12-16 | Immco Diagnostics | Solution-phase elisa |
US20070218508A1 (en) * | 1998-06-10 | 2007-09-20 | Kent State University | Detection and amplification of ligands |
US7927827B2 (en) | 1998-06-10 | 2011-04-19 | Kent State University | Detection and amplification of ligands |
US7732219B2 (en) | 1998-06-10 | 2010-06-08 | Kent State University | Detection and amplification of ligands |
US20070243593A1 (en) * | 1998-06-10 | 2007-10-18 | Kent State University | Detection and amplification of ligands |
US20070059780A1 (en) * | 1998-06-10 | 2007-03-15 | Kent State University | Detection and amplification of ligands |
US20080138244A1 (en) * | 1998-06-10 | 2008-06-12 | Kent State University | Detection and amplification of ligands |
US7267957B2 (en) * | 1998-06-10 | 2007-09-11 | Kent State University | Detection and amplification of ligands |
US8163315B2 (en) | 1998-07-21 | 2012-04-24 | Danisco A/S | Foodstuff |
US7972638B2 (en) | 1998-07-21 | 2011-07-05 | Danisco A/S | Foodstuff |
US20090098245A1 (en) * | 1998-07-21 | 2009-04-16 | Jorn Borch Soe | Foodstuff |
US6844433B2 (en) | 1998-07-31 | 2005-01-18 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20040002595A1 (en) * | 1998-07-31 | 2004-01-01 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20030232979A1 (en) * | 1998-07-31 | 2003-12-18 | Mcgall Glenn | Nucleic acid labeling compounds |
US20050164268A1 (en) * | 1998-07-31 | 2005-07-28 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US7179905B2 (en) | 1998-07-31 | 2007-02-20 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US7491818B2 (en) | 1998-07-31 | 2009-02-17 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US6187563B1 (en) | 1998-08-07 | 2001-02-13 | Yale University | βIV-spectrin-polypeptides and nucleic acids encoding same |
WO2000015824A1 (en) | 1998-09-13 | 2000-03-23 | Karolinska Innovations Ab | Transfer method for specific cellular localisation of nucleic acids |
EP1897949A2 (en) | 1998-09-21 | 2008-03-12 | Schering Corporation | Human interleukin-B50. Therapeutic uses |
EP2314696A1 (en) | 1998-09-21 | 2011-04-27 | Schering Corporation | Therapeutic uses of human Interleukin-B50 antagonist. |
EP1983001A2 (en) | 1998-09-25 | 2008-10-22 | Schering Corporation | Antibodies to mammalian Langerhans cell antigen and their uses |
EP2341144A1 (en) | 1999-01-11 | 2011-07-06 | Schering Corporation | Interleukin-17 related mammalian cytokines. Polynucleotides encoding them. Uses |
US7993830B2 (en) | 1999-02-09 | 2011-08-09 | Laboratory Corporation Of America Holdings | Prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
US20080044416A1 (en) * | 1999-02-09 | 2008-02-21 | Gang An | Novel, prostate-specific gene for diagnosis, prognosis and management of prostate cancer |
US7025961B1 (en) | 1999-03-04 | 2006-04-11 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-plasmodium composition and methods of use |
EP1942114A2 (en) | 1999-03-11 | 2008-07-09 | Schering Corporation | Mammalian cytokines; related reagents and methods |
US20090170072A1 (en) * | 1999-03-29 | 2009-07-02 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
US8062908B2 (en) | 1999-03-29 | 2011-11-22 | Orasure Technologies, Inc. | Device for collection and assay of oral fluids |
EP1762243A1 (en) | 1999-03-31 | 2007-03-14 | Oxford Biomedica (UK) Ltd | Factor for regulation of neurite growth |
EP2341143A1 (en) | 1999-05-13 | 2011-07-06 | Medical Research Council | OX2 receptor homolog |
EP2336321A1 (en) | 1999-05-13 | 2011-06-22 | Medical Research Council | Ox2 receptor homolog |
EP2385124A2 (en) | 1999-05-14 | 2011-11-09 | Arbor Vita Corporation | Peptides or peptide analogues for modulating the binding of a PDZ protein and a PL protein |
WO2000073451A1 (en) | 1999-06-01 | 2000-12-07 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
EP1950299A1 (en) | 1999-06-01 | 2008-07-30 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
EP2258849A1 (en) | 1999-06-01 | 2010-12-08 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
US7053268B1 (en) | 1999-06-17 | 2006-05-30 | Danisco A/S | Promoter |
US6262265B1 (en) | 1999-06-18 | 2001-07-17 | Microgenics Corporation | Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay |
US6531130B1 (en) | 1999-07-06 | 2003-03-11 | The Board Of Trustees Of The Leland Stanford University | Treatment of demyelinating autoimmune disease with ordered peptides |
US6403807B1 (en) | 1999-07-06 | 2002-06-11 | Surromed, Inc. | Bridged fluorescent dyes, their preparation and their use in assays |
US7070780B2 (en) | 1999-07-06 | 2006-07-04 | Board Of Trustees Of The Leland Stanford Junior University | Treatment of demyelinating autoimmune disease with ordered peptides |
US20020137681A1 (en) * | 1999-07-06 | 2002-09-26 | Lawrence Steinman | Treatment of demyelinating autoimmune disease with ordered peptides |
EP2138510A1 (en) | 1999-07-30 | 2009-12-30 | Schering Corporation | Methods of generating antibodies against cytokines |
US20090087865A1 (en) * | 1999-08-03 | 2009-04-02 | Siemens Healthcare Diagnostics Inc. | Monoclonal Antibodies to Tacrolimus and Immunoassays Methods for Tacrolimus |
US7078495B1 (en) | 1999-08-03 | 2006-07-18 | Dade Behring Inc. | Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus |
US8030458B2 (en) | 1999-08-03 | 2011-10-04 | Siemens Healthcare Diagnostics Inc. | Monoclonal antibodies to tacrolimus and immunoassays methods for tacrolimus |
US20060216770A1 (en) * | 1999-08-03 | 2006-09-28 | Kasper Kenneth C | Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus |
EP3184637A1 (en) | 1999-09-09 | 2017-06-28 | Merck Sharp & Dohme Corp. | Mammalian interleukin-12 p40 and interleukin b30 complexes, antibodies, uses in pharmaceutical compositions |
EP1905832A2 (en) | 1999-09-09 | 2008-04-02 | Schering Corporation | Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions |
US7668658B2 (en) | 1999-10-13 | 2010-02-23 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
US8229677B2 (en) | 1999-10-13 | 2012-07-24 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
US8818735B2 (en) | 1999-10-13 | 2014-08-26 | Sequenom, Inc. | Methods for generating databases and databases for identifying polymorphic genetic markers |
US20060233840A1 (en) * | 1999-11-15 | 2006-10-19 | Miltenyi Biotech Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
US8183039B2 (en) | 1999-11-15 | 2012-05-22 | Miltenyi Biotec Gmbh | Method for isolating BDCA-4+ dendritic cells |
US10407486B2 (en) | 1999-11-15 | 2019-09-10 | Miltenyi Biotech Gmbh | Ligating BDCA-2 protein with BDCA-2 specific antibody for detecting or modulating dendritic cells |
EP2275447A1 (en) | 1999-11-24 | 2011-01-19 | Schering Corporation | Methods of inhibiting metastasis |
EP2261256A2 (en) | 1999-11-24 | 2010-12-15 | Schering Corporation | Methods of inhibiting metastasis |
EP2336775A2 (en) | 1999-12-06 | 2011-06-22 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
EP2042869A2 (en) | 1999-12-06 | 2009-04-01 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
EP2287185A2 (en) | 1999-12-06 | 2011-02-23 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
US6544792B1 (en) | 1999-12-21 | 2003-04-08 | Genencor International, Inc. | Production of secreted polypeptides |
US7407791B2 (en) | 1999-12-21 | 2008-08-05 | Genencor International, Inc. | Production of secreted polypeptides |
US20050090644A1 (en) * | 1999-12-21 | 2005-04-28 | Diaz-Torres Maria R. | Production of secreted polypeptides |
US6642027B2 (en) | 1999-12-21 | 2003-11-04 | Genecor International, Inc. | Production of secreted polypeptides |
US20070053840A1 (en) * | 1999-12-23 | 2007-03-08 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
US7897140B2 (en) | 1999-12-23 | 2011-03-01 | Health Research, Inc. | Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents |
US7320786B2 (en) | 2000-01-12 | 2008-01-22 | Light Sciences Oncology, Inc. | Photodynamic therapy treatment for eye disease |
US20020154615A1 (en) * | 2000-01-28 | 2002-10-24 | Martin Hans | Detection method and device |
US20110207664A1 (en) * | 2000-02-25 | 2011-08-25 | Vegenics Pty Limited | Materials and Methods Involving Hybrid Vascular Endothelial Growth Factor DNAs and Proteins |
US8278098B2 (en) | 2000-02-25 | 2012-10-02 | Vegenics Pty Limited | Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins |
US7829313B2 (en) | 2000-03-24 | 2010-11-09 | Eppendorf Array Technologies | Identification and quantification of a plurality of biological (micro)organisms or their components |
US20070099204A1 (en) * | 2000-03-24 | 2007-05-03 | Isabelle Alexandre | Identification and quantification of a plurality of biological (micro)organisms or their components |
US7875442B2 (en) | 2000-03-24 | 2011-01-25 | Eppendorf Array Technologies | Identification and quantification of a plurality of biological (micro)organisms or their components |
US20070037187A1 (en) * | 2000-03-24 | 2007-02-15 | Isabelle Alexandre | Identification and quantification of a plurality of biological (micro)organisms or their components |
US20030108927A1 (en) * | 2000-04-03 | 2003-06-12 | Kathryn Leishman | Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases |
EP1964921A2 (en) | 2000-04-05 | 2008-09-03 | Oscient Pharmaceuticals Corporation | The high bone mass gene of 11q13.3 |
EP2389943A1 (en) | 2000-04-18 | 2011-11-30 | Schering Corporation | Use of IL-174 antagonists for treating Th2-related diseases |
EP2020239A1 (en) | 2000-04-18 | 2009-02-04 | Schering Corporation | Use of IL-174 agonists for treating infectious diseases |
EP2341349A1 (en) | 2000-05-04 | 2011-07-06 | Siemens Healthcare Diagnostics Products GmbH | Methods for detection of multiple analytes |
EP1918377A1 (en) | 2000-05-10 | 2008-05-07 | Schering Corporation | Mammalian cytokine receptor subunit proteins, related reagents and methods |
EP2275548A1 (en) | 2000-05-10 | 2011-01-19 | Schering Corporation | Mammalian cytokine receptor subunit proteins, related reagents and methods |
EP1908837A2 (en) | 2000-05-25 | 2008-04-09 | Schering Corporation | Human receptor proteins, related reagents and methods |
US20060003358A1 (en) * | 2000-07-10 | 2006-01-05 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
US6958214B2 (en) | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
GR20000100255A (en) * | 2000-07-26 | 2002-09-06 | Αυτοματοι Αναλυτες Και Διαγνωστικα Αντιδραστηρια Medicon Hellas.. | DEVELOPMENT OF A NEW HOMOGENEOUS IMMUNOENZYMIC METHOD FOR THE PRODUCTION OF A CLINICAL LABORATORY TEST SYSTEM (kit) FOR THE QUANTIFICATION OF THYROXINE AND TRIIODOTHYRONINE IN HUMAN SERUM, UTILIZING POLYIODOTHYRONINE CONJUGATED WITH GLYCOGEN PHOSPHO.... |
US20060153881A1 (en) * | 2000-08-07 | 2006-07-13 | Narum David L | Anti-plasmodium compositions and methods of use |
US7303751B2 (en) | 2000-08-07 | 2007-12-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-plasmodium compositions and methods of use |
EP2202240A1 (en) | 2000-08-18 | 2010-06-30 | Sterix Limited | Compound |
EP2028187A1 (en) | 2000-09-08 | 2009-02-25 | Board Of Regents, The University Of Texas System | Human and mouse targeting peptides identified by phage display |
WO2002020569A2 (en) | 2000-09-08 | 2002-03-14 | Schering Corporation | Mammalian genes; related reagents and methods |
EP2298789A1 (en) | 2000-09-08 | 2011-03-23 | Schering Corporation | Mammalian genes; related reagents and methods |
US6673623B1 (en) | 2000-09-12 | 2004-01-06 | Novocure, Inc. | Methods and compositions that control lipid production |
US20020110860A1 (en) * | 2000-09-18 | 2002-08-15 | Sierd Bron | Twin-arginine translocation in Bacillus |
US7884192B2 (en) | 2000-09-18 | 2011-02-08 | Danisco Us Inc. | Twin-arginine translocation in Bacillus |
US7884191B2 (en) | 2000-09-18 | 2011-02-08 | Danisco Us Inc. | Twin-arginine translocation in Bacillus |
US7897742B2 (en) | 2000-09-18 | 2011-03-01 | Danisco Us Inc. | Twin-arginine translocation in Bacillus |
US20080248525A1 (en) * | 2000-09-18 | 2008-10-09 | Sierd Bron | Twin-Arginine translocation in bacillus |
US7316924B2 (en) | 2000-09-18 | 2008-01-08 | Genencor International, Inc. | Twin-arginine translocation in Bacillus |
US20080166757A1 (en) * | 2000-09-18 | 2008-07-10 | Sierd Bron | Twin-arginine translocation in Bacillus |
EP2341346A2 (en) | 2000-10-18 | 2011-07-06 | The Regents of the University of California | Methods of high-throughput screening for internalizing antibodies and metal-chelating liposomes |
EP2292760A2 (en) | 2000-11-10 | 2011-03-09 | Schering Corporation | Mammalian cytokines, receptors, related reagents and methods |
US20020172980A1 (en) * | 2000-11-27 | 2002-11-21 | Phan Brigitte Chau | Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems |
US20030003464A1 (en) * | 2000-11-27 | 2003-01-02 | Phan Brigitte C. | Dual bead assays including optical biodiscs and methods relating thereto |
US20040248093A1 (en) * | 2000-11-27 | 2004-12-09 | Coombs James Howard | Magneto-optical bio-discs and systems including related methods |
US20030054446A1 (en) * | 2000-11-29 | 2003-03-20 | Weber Bernard H. F. | Novel retina-specific human proteins C7orf9, C12orf7, MPP4 and F379 |
US20020165149A1 (en) * | 2000-12-08 | 2002-11-07 | Kranz David M. | Mutated class II major histocompatibility proteins |
US7087395B1 (en) | 2001-01-16 | 2006-08-08 | Quest Diagnostics Investments Incorporated | Vitamin D assay |
US20080108085A1 (en) * | 2001-01-23 | 2008-05-08 | D-Gen Limited | Method and Detection of the Presence of Prions Protein |
US20040132109A1 (en) * | 2001-01-23 | 2004-07-08 | Masato Enari | Method |
US20110082289A1 (en) * | 2001-03-12 | 2011-04-07 | Affymetric, Inc. | Nucleic Acid Labeling Compounds |
US7468243B2 (en) | 2001-03-12 | 2008-12-23 | Affymetrix, Inc. | 2-aminopyrimidin-4-one nucleic acid labeling compounds |
US8026057B2 (en) | 2001-03-12 | 2011-09-27 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US20080287667A1 (en) * | 2001-03-12 | 2008-11-20 | Affymetrix, Inc. | Nucleic Acid Labeling Compounds |
US8076072B2 (en) | 2001-03-12 | 2011-12-13 | Affymetrix, Inc. | Nucleic acid labeling compounds |
US8497064B2 (en) | 2001-03-12 | 2013-07-30 | Affymetrix, Inc. | Nucleic acid labelling compounds |
US20030104410A1 (en) * | 2001-03-16 | 2003-06-05 | Affymetrix, Inc. | Human microarray |
US20030220475A1 (en) * | 2001-04-03 | 2003-11-27 | Fields Howard A. | Neutralizing immunogenic hev polypepetides |
US20040214248A1 (en) * | 2001-04-06 | 2004-10-28 | Roberts David D | Use of semenogelin in the diagnosis, prognosis and treatment of cancer |
US20100112626A1 (en) * | 2001-04-06 | 2010-05-06 | The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services | Use of Semenogelin in the Diagnosis, Prognosis and Treatment of Cancer |
US7618789B2 (en) | 2001-04-06 | 2009-11-17 | The United States Of America As Represented By The Secretary Of Department Of Health And Human Services | Use of semenogelin in the diagnosis, prognosis and treatment of cancer |
US20050281916A1 (en) * | 2001-05-18 | 2005-12-22 | Kirsten Bojsen | Method of improving dough and bread quality |
USRE43135E1 (en) | 2001-05-18 | 2012-01-24 | Danisco A/S | Method of improving dough and bread quality |
EP1990057A1 (en) | 2001-05-22 | 2008-11-12 | Merck & Co., Inc. | Beta-secretase substrates and uses thereof |
US20070190534A1 (en) * | 2001-06-11 | 2007-08-16 | Genesis Genomics Inc. | Mitochondrial sites and genes associated with prostate cancer |
US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
US8722866B2 (en) | 2001-08-01 | 2014-05-13 | The United States Of America, As Represented By The Department Of Veterans Affairs | Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases |
US20050009139A1 (en) * | 2001-08-01 | 2005-01-13 | Caili Wang | Compositions and methods for generating chimeric heteromultimers |
US20030158133A1 (en) * | 2001-08-01 | 2003-08-21 | Movsesian Matthew A. | Isoform-selective inhibitors and activators of PDE3 cyclic nucleotide phosphodiesterases |
US7429652B2 (en) | 2001-08-01 | 2008-09-30 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
US20100267046A1 (en) * | 2001-08-01 | 2010-10-21 | University Of Utah Research Foundation | Isoform-selective inhibitor and activators of pde3 cyclic nucleotide phosphodiesterases |
US20030082596A1 (en) * | 2001-08-08 | 2003-05-01 | Michael Mittmann | Methods of genetic analysis of probes: test3 |
US20060073530A1 (en) * | 2001-08-15 | 2006-04-06 | Olaf Schneewind | Methods and compositions involving sortase B |
US8118991B2 (en) | 2001-09-04 | 2012-02-21 | Stephen Eliot Zweig | Apoenzyme reactivation electrochemical detection method and assay |
US20070289880A1 (en) * | 2001-09-04 | 2007-12-20 | Zweig Stephen E | Apoenzyme reactivation electrochemical detection method and assay |
EP2131198A2 (en) | 2001-09-20 | 2009-12-09 | Board of Regents, The University of Texas System | Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays |
US7393696B2 (en) | 2001-09-28 | 2008-07-01 | Aspenbio Pharma, Inc. | Bovine pregnancy test |
US20030073248A1 (en) * | 2001-09-28 | 2003-04-17 | J.W. Roth | Bovine pregnancy test |
US7687281B2 (en) | 2001-09-28 | 2010-03-30 | Aspenbio Pharma, Inc. | Bovine pregnancy test |
EP2070944A1 (en) | 2001-10-11 | 2009-06-17 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
EP2272869A2 (en) | 2001-10-11 | 2011-01-12 | Amgen Inc. | Angiopoietin-2 specific binding agents |
EP2157097A1 (en) | 2001-10-11 | 2010-02-24 | Amgen, Inc. | Specific binding agents of human angiopoietin-2 |
EP2316845A1 (en) | 2001-10-11 | 2011-05-04 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
EP2072059A1 (en) | 2001-10-12 | 2009-06-24 | Schering Corporation | Use of bispecific antibodies to regulate immune responses |
WO2003030835A2 (en) | 2001-10-12 | 2003-04-17 | Schering Corporation | Use of bispecific antibodies to regulate immune responses |
EP2316485A1 (en) | 2001-10-12 | 2011-05-04 | Schering Corporation | Use of bispecific antibodies to regulate immune responses |
US20050009031A1 (en) * | 2001-10-25 | 2005-01-13 | Becker Kenneth David | Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases |
US20030224380A1 (en) * | 2001-10-25 | 2003-12-04 | The General Hospital Corporation | Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases |
US20030170678A1 (en) * | 2001-10-25 | 2003-09-11 | Neurogenetics, Inc. | Genetic markers for Alzheimer's disease and methods using the same |
US20060281181A1 (en) * | 2001-11-02 | 2006-12-14 | Caili Wang | Adaptor-directed helper systems |
US20030104355A1 (en) * | 2001-11-02 | 2003-06-05 | Caili Wang | Adapter-directed display systems |
US7175983B2 (en) | 2001-11-02 | 2007-02-13 | Abmaxis, Inc. | Adapter-directed display systems |
US7910350B2 (en) | 2001-11-02 | 2011-03-22 | Abmaxis, Inc. | Adaptor-directed helper systems |
WO2003043524A2 (en) | 2001-11-20 | 2003-05-30 | The Curators Of The University Of Missouri | Compositions and methods for accurate early pregnancy diagnosis |
WO2003046201A2 (en) | 2001-11-21 | 2003-06-05 | Kimberly-Clark Worldwide, Inc. | Detection and identification of enteric bacteria |
US20030105770A1 (en) * | 2001-11-26 | 2003-06-05 | Macleod Stewart | Extending a directory schema independent of schema modification |
US9575070B2 (en) | 2001-12-04 | 2017-02-21 | Wayne State University | Neoepitope detection of disease using protein arrays |
US20080267999A1 (en) * | 2001-12-04 | 2008-10-30 | Tainsky Michael A | Neoepitope detection of disease using protein arrays |
EP2077277A1 (en) | 2002-02-01 | 2009-07-08 | Schering Corporation | Use of mammalian cytokine; related reagents |
EP2311869A1 (en) | 2002-02-01 | 2011-04-20 | Schering Corporation | Use of mammalian cytokine; related reagents |
EP3031910A1 (en) | 2002-02-21 | 2016-06-15 | Institute Of Virology | Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use |
EP2508596A2 (en) | 2002-02-21 | 2012-10-10 | Bayer Healthcare | MN/CA IX-specific monoclonal antibodies generated from MN/CA IX-deficient mice and methods of use |
US7053188B2 (en) | 2002-02-22 | 2006-05-30 | Purdue Research Foundation | Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase |
WO2003072799A2 (en) | 2002-02-22 | 2003-09-04 | The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Brother of the regulator of imprinted sites (boris) |
US20050158809A1 (en) * | 2002-04-16 | 2005-07-21 | The Regents Of The University Of Califorina | Methods of renal cell carcinoma prognosis and treatment selection with carbonic anhydrase IX |
US8936914B2 (en) | 2002-04-16 | 2015-01-20 | The Regents Of The University Of California | Methods of renal cell carcinoma prognosis and treatment selection with carbonic anhydrase IX |
US20040009164A1 (en) * | 2002-05-01 | 2004-01-15 | Jonathan Reeves | PSP94 diagnostic reagents and assays |
US20060029984A1 (en) * | 2002-05-01 | 2006-02-09 | Jonathan Reeves | PSP94 diagnostic reagents and assays |
US7842513B2 (en) | 2002-05-02 | 2010-11-30 | Aspenbio Pharma, Inc. | Pregnancy detection |
US20030224452A1 (en) * | 2002-05-02 | 2003-12-04 | Mark Colgin | Pregnancy detection |
US7432342B2 (en) | 2002-05-03 | 2008-10-07 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof and related documents |
US20050287604A1 (en) * | 2002-05-31 | 2005-12-29 | Bohmer Ralph M | Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood |
US7785898B2 (en) | 2002-05-31 | 2010-08-31 | Genetic Technologies Limited | Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood |
US20030224373A1 (en) * | 2002-06-04 | 2003-12-04 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes |
US7560239B2 (en) | 2002-06-04 | 2009-07-14 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for simultaneous detection of multiple analytes |
USRE43274E1 (en) | 2002-06-27 | 2012-03-27 | Health Research, Inc. | Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy |
US7501509B2 (en) | 2002-06-27 | 2009-03-10 | Health Research, Inc. | Water soluble tetrapyrollic photosensitizers for photodynamic therapy |
US7820143B2 (en) | 2002-06-27 | 2010-10-26 | Health Research, Inc. | Water soluble tetrapyrollic photosensitizers for photodynamic therapy |
US20040044198A1 (en) * | 2002-07-02 | 2004-03-04 | Pandey Ravindra K. | Efficient synthesis of pyropheophorbide a and its derivatives |
US7053210B2 (en) | 2002-07-02 | 2006-05-30 | Health Research, Inc. | Efficient synthesis of pyropheophorbide a and its derivatives |
EP2281578A2 (en) | 2002-07-15 | 2011-02-09 | Board of Regents, The University of Texas System | Selected antibodies and duramycin peptides binding to anionic phospholipids and aminophospholipids and their use in treating viral infections and cancer |
WO2005019409A2 (en) | 2002-07-15 | 2005-03-03 | Board Of Regents, The University Of Texas System | Combinatorial protein library screening by periplasmic expression |
EP2266624A2 (en) | 2002-07-15 | 2010-12-29 | Board of Regents, The University of Texas System | Duramycin peptide binding to anionic phospholipids and aminophospholipids conjugates and their use in treating viral infections |
US8828386B2 (en) | 2002-07-25 | 2014-09-09 | Glenveigh Pharmaceuticals, Llc | Method for extending pregnancy by reducing intraventricular hemorrhaging in patients exhibiting at least one symptom of preeclampsia and eclampsia |
US8030456B2 (en) | 2002-08-10 | 2011-10-04 | Yale University | Nogo receptor antagonists |
US7465705B2 (en) | 2002-08-10 | 2008-12-16 | Yale University | Nogo receptor antagonists |
US20050271655A1 (en) * | 2002-08-10 | 2005-12-08 | Biogen Idec Ma Inc. | Nogo receptor antagonists |
US8114610B2 (en) | 2002-08-13 | 2012-02-14 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
US9568479B2 (en) | 2002-08-13 | 2017-02-14 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
US20060240498A1 (en) * | 2002-08-13 | 2006-10-26 | Michael Friedman | Devices and methods for detecting amniotic fluid in vaginal secretions |
US7709272B2 (en) | 2002-08-13 | 2010-05-04 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
US10422802B2 (en) | 2002-08-13 | 2019-09-24 | Qiagen Sciences, Llc | Devices and methods for detecting amniotic fluid in vaginal secretions |
US9494596B2 (en) | 2002-08-13 | 2016-11-15 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
US9429580B2 (en) | 2002-08-13 | 2016-08-30 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
EP2204654A1 (en) | 2002-08-13 | 2010-07-07 | N-Dia, Inc. | Devices and methods for detecting amniotic fluid in vaginal secretions |
EP2026070A1 (en) | 2002-09-09 | 2009-02-18 | Arbor Vita Corporation | Methods of diagnosing cervical cancer |
US20040106158A1 (en) * | 2002-10-21 | 2004-06-03 | Tabassum Naqvi | IP3 protein binding assay |
WO2004037251A1 (en) | 2002-10-24 | 2004-05-06 | Sterix Limited | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2 |
US20060198817A1 (en) * | 2002-11-26 | 2006-09-07 | Alverdy John C | Materials and methods for preventing and treating microbe-mediated epithelial disorders |
US9549946B2 (en) | 2002-11-26 | 2017-01-24 | The University Of Chicago | Materials and methods for preventing and treating microbe-mediated epithelial disorders |
EP2031070A1 (en) | 2002-12-04 | 2009-03-04 | Applera Corporation | Multiplex amplification of polynucleotides |
EP3000899A1 (en) | 2002-12-04 | 2016-03-30 | Applied Biosystems, LLC | Multiplex amplification of polynucleotides |
EP2194147A1 (en) | 2002-12-04 | 2010-06-09 | Applied Biosystems, LLC | Multiplex amplification of polynucleotides |
WO2004060909A2 (en) | 2002-12-04 | 2004-07-22 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms |
US20040229245A1 (en) * | 2003-01-06 | 2004-11-18 | Anton Bittner | Methods and algorithms for performing quality control during gene expression profiling on DNA microarray technology |
US8278062B2 (en) | 2003-01-14 | 2012-10-02 | Dupont Nutrition Biosciences Aps | Method of using lipid acyltransferase |
US20070026106A1 (en) * | 2003-01-17 | 2007-02-01 | Kreij Arno D | Method |
EP2287317A2 (en) | 2003-01-17 | 2011-02-23 | Danisco A/S | Method of producing a protein ester or a protein subunit ester |
US7955813B2 (en) | 2003-01-17 | 2011-06-07 | Danisco, A/S | Method of using lipid acyltransferase |
US20080063783A1 (en) * | 2003-01-17 | 2008-03-13 | Kreij Arno D | Method |
EP3323887A2 (en) | 2003-01-17 | 2018-05-23 | DuPont Nutrition Biosciences ApS | Method for the in situ production of an emulsifier in a foodstuff |
US20070122525A1 (en) * | 2003-01-17 | 2007-05-31 | Kreij Arno D | Method |
EP2290085A2 (en) | 2003-01-17 | 2011-03-02 | Danisco A/S | Method for the in situ production of an emulsifier in a foodstuff |
US8003095B2 (en) | 2003-01-17 | 2011-08-23 | Danisco A/S | Method of using lipid acyltransferase |
US7955814B2 (en) | 2003-01-17 | 2011-06-07 | Danisco A/S | Method |
EP2278015A1 (en) | 2003-01-17 | 2011-01-26 | Danisco A/S | Method of producing a carbohydrate ester |
US20050032126A1 (en) * | 2003-03-03 | 2005-02-10 | Coombs James H. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
US20070134658A1 (en) * | 2003-03-05 | 2007-06-14 | Genetic Technologies Limited, A.C.N. 009 212 328 | Identification of fetal dna and fetal cell markers in maternal plasma or serum |
US8394582B2 (en) | 2003-03-05 | 2013-03-12 | Genetic Technologies, Inc | Identification of fetal DNA and fetal cell markers in maternal plasma or serum |
US20070141570A1 (en) * | 2003-03-07 | 2007-06-21 | Sequenom, Inc. | Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods |
WO2004096157A2 (en) | 2003-03-07 | 2004-11-11 | New England Medical Center Hospitals, Inc. | Treatment of igai deposition diseases |
US20050003147A1 (en) * | 2003-03-24 | 2005-01-06 | Anderson-Tully Engineered Wood Llc | Laminated board and methods of producing the same |
EP2330132A1 (en) | 2003-04-04 | 2011-06-08 | Yeda Research and Development Co. Ltd. | Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins |
US20070065429A1 (en) * | 2003-04-16 | 2007-03-22 | Biogen Idec Ma Inc. | Nogo-receptor antagonists for the treatment of conditions involving amyloid plaques |
US7355079B2 (en) | 2003-04-18 | 2008-04-08 | The Regents Of The University Of California | Thyronamine derivatives and analogs and methods of use thereof |
US20060035980A1 (en) * | 2003-04-18 | 2006-02-16 | Scanlan Thomas S | Thyronamine derivatives and analogs and methods of use thereof |
US20090036321A1 (en) * | 2003-06-03 | 2009-02-05 | Chiron Corporation | Methods for predicting the course of a malignant disease |
US20050283861A1 (en) * | 2003-06-26 | 2005-12-22 | The J. C. Robinson Seed Co. | Inbred corn line w23129 |
US20110229495A1 (en) * | 2003-07-07 | 2011-09-22 | Wagner David H | Methods for predicting development of auto-immune diseases and treatment of same |
US9341637B2 (en) | 2003-07-08 | 2016-05-17 | Accumetrics Inc. | Controlled platelet activation to monitor therapy of ADP antagonists |
US8574828B2 (en) | 2003-07-08 | 2013-11-05 | Accumetrics, Inc. | Controlled platelet activation to monitor therapy of ADP antagonists |
US9506938B2 (en) | 2003-07-08 | 2016-11-29 | Accumetrics, Inc. | Methods for measuring platelet reactivity of individuals treated with drug eluting stents |
US20100184084A1 (en) * | 2003-07-08 | 2010-07-22 | Barry Coller | Methods for measuring platelet reactivity of individuals treated with drug eluting stents |
US20110065125A1 (en) * | 2003-07-08 | 2011-03-17 | Accumetrics, Inc. | Controlled platelet activation to monitor therapy of adp antagonists |
EP2128270A1 (en) | 2003-08-08 | 2009-12-02 | Genenews Inc. | Osteoarthritis biomarkers and uses thereof |
US20050064479A1 (en) * | 2003-08-12 | 2005-03-24 | Affymetrix, Inc. | Compounds and methods for post incorporation labeling of nucleic acids |
WO2005016282A2 (en) | 2003-08-14 | 2005-02-24 | Exelixis, Inc. | Prkcs as modifiers of the beta catenin pathway and methods of use |
US7875713B2 (en) | 2003-09-04 | 2011-01-25 | Technion Research & Development Foundation Ltd. | Synthetic binding pairs comprising cucurbituril derivatives and polyammonium compounds and uses thereof |
US20060292570A1 (en) * | 2003-09-04 | 2006-12-28 | Technion Research & Development Foundation Ltd. | Novel synthetic binding pairs and uses thereof |
EP2280286A1 (en) | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus |
EP2287616A1 (en) | 2003-09-15 | 2011-02-23 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus |
EP2280285A1 (en) | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases |
US20060199216A1 (en) * | 2003-09-24 | 2006-09-07 | Intel Corporation | Programmable molecular barcodes |
US20070054288A1 (en) * | 2003-09-24 | 2007-03-08 | Intel Corporation | Programmable molecular barcodes |
US9447454B2 (en) | 2003-10-23 | 2016-09-20 | The Rockefeller University | Method of purifying RNA binding protein-RNA complexes |
EP2301575A1 (en) | 2003-11-04 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for solid tumors expressing the CD40 cell-surface antigen |
EP2243492A1 (en) | 2003-11-04 | 2010-10-27 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-cd40 monoclonal antibodies for treatment of multiple myeloma |
EP2243491A1 (en) | 2003-11-04 | 2010-10-27 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-CD40 monoclonal antibodies for treatment of chronic lymphocytic leukemia |
EP2149585A1 (en) | 2003-11-04 | 2010-02-03 | Novartis Vaccines and Diagnostics, Inc. | Antagonist anti-CD40 monoclonal antibodies and methods for their use |
EP2248830A1 (en) | 2003-11-04 | 2010-11-10 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-CD40 antibodies for treatment of autoimmune and inflammatory diseases and organ transplant rejection |
EP2292661A2 (en) | 2003-11-10 | 2011-03-09 | Schering Corporation | Interleukin-10 antibodies |
WO2005048771A1 (en) | 2003-11-18 | 2005-06-02 | Atsushi Takahashi | Resin twisting brush |
EP2256203A1 (en) | 2003-11-21 | 2010-12-01 | Schering Corporation | IL-23 and its receptor; related reagents and methods |
WO2005058864A1 (en) | 2003-12-15 | 2005-06-30 | Dade Behring Inc. | Assay for entactogens |
WO2005061482A1 (en) | 2003-12-15 | 2005-07-07 | Dade Behring Inc. | Ecstasy haptens and immunogens |
US9611315B2 (en) | 2003-12-23 | 2017-04-04 | Arbor Vita Corporation | Antibodies for oncogenic strains of HPV and methods of their use |
US8030044B2 (en) | 2003-12-24 | 2011-10-04 | Danisco A/S | Lipid acyltransferases |
US20100062501A1 (en) * | 2003-12-24 | 2010-03-11 | Paul Wassell | Method |
US8440435B2 (en) | 2003-12-24 | 2013-05-14 | Dupont Nutrition Biosciences Aps | Method for reducing 1,2-diglyceride content of an edible oil |
EP2119771A2 (en) | 2003-12-24 | 2009-11-18 | Danisco A/S | Proteins |
US20090181124A1 (en) * | 2003-12-24 | 2009-07-16 | Danisco A/S | Proteins |
US20050186646A1 (en) * | 2004-01-26 | 2005-08-25 | Cruz Miguel A. | Rapid assay to detect ADAMTS-13 activity |
US20070178462A1 (en) * | 2004-02-18 | 2007-08-02 | Uebele Victor N | Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha1h, encoded proteins and methods of use thereof |
EP2177503A1 (en) | 2004-02-20 | 2010-04-21 | UCL Business PLC | Modulators of cannabinoid receptors |
EP2208797A2 (en) | 2004-03-01 | 2010-07-21 | Applied Biosystems, LLC | Methods, compositions and kits for use in polynucleotide amplification |
US20050196820A1 (en) * | 2004-03-03 | 2005-09-08 | Zweig Stephen E. | Apoenzyme reactivation electrochemical detection method and assay |
US7166208B2 (en) | 2004-03-03 | 2007-01-23 | Stephen Eliot Zweig | Apoenzyme reactivation electrochemical detection method and assay |
US8012732B2 (en) | 2004-03-12 | 2011-09-06 | Danisco A/S | Fungal lypolytic and amylase enzyme composition and methods using the same |
EP2266405A2 (en) | 2004-03-12 | 2010-12-29 | Danisco A/S | Fungal lipolytic enzymes |
US20080206188A1 (en) * | 2004-04-20 | 2008-08-28 | Alverdy John C | Therapeutic Delivery System Comprising a High Molecular Weight Peg-Like Compound |
EP2400030A1 (en) | 2004-05-18 | 2011-12-28 | The Board Of Trustees Of The University Of the Leland Stanford Junior University | Detection of protein translocation by beta-galactosidase reporter fragment complementation |
WO2005118864A2 (en) | 2004-05-28 | 2005-12-15 | Agensys, Inc. | Antibodies and related molecules that bind to psca proteins |
EP2583981A2 (en) | 2004-05-28 | 2013-04-24 | Agensys, Inc. | Antibodies and related molecules that bind to PSCA proteins |
EP2428522A1 (en) | 2004-05-28 | 2012-03-14 | Agensys, Inc. | Antibodies that bind to PSCA proteins for diagnosis of cancer |
US8034553B2 (en) | 2004-06-24 | 2011-10-11 | Kimberly-Clark Worldwide, Inc. | Biomarkers for wound healing |
US20060019285A1 (en) * | 2004-06-30 | 2006-01-26 | Joseph Horecka | Analysis of intracellular modifications |
US7608415B2 (en) | 2004-06-30 | 2009-10-27 | Discoverx Corporation | Analysis of intracellular modifications |
US8535900B2 (en) | 2004-07-16 | 2013-09-17 | Dupont Nutrition Biosciences Aps | Lipolytic enzyme uses thereof in the food industry |
US20110014317A1 (en) * | 2004-07-16 | 2011-01-20 | Andrei Miasnikov | Lipolytic enzyme uses thereof in the food industry |
US8192782B2 (en) | 2004-07-16 | 2012-06-05 | Danisco A/S | Enzymatic oil-degumming method |
US20070298157A1 (en) * | 2004-07-16 | 2007-12-27 | Soe Jorn B | Enzymatic oil-degumming method |
EP2275522A2 (en) | 2004-07-16 | 2011-01-19 | Danisco A/S | Enzymatic oil-degumming method |
EP2267108A1 (en) | 2004-07-16 | 2010-12-29 | Danisco A/S | Enzymatic oil-degumming method |
EP2267107A2 (en) | 2004-07-16 | 2010-12-29 | Danisco A/S | Lipolytic Enzyme. Uses Thereof In The Food Industry |
US8889371B2 (en) | 2004-07-16 | 2014-11-18 | Dupont Nutrition Biosciences Aps | Lipolytic enzyme: uses thereof in the food industry |
US20090035784A1 (en) * | 2004-07-30 | 2009-02-05 | Mount Sinai School Of Medicine Of New York University | Npc1l1 and npc1l1 inhibitors and methods of use thereof |
US20090208533A1 (en) * | 2004-08-11 | 2009-08-20 | University Of Georgia Research Foundation, Inc. | Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions |
US7883876B2 (en) | 2004-08-11 | 2011-02-08 | Stephens David S | Neisseria meningitidis serogroup A capsular polysaccharide acetyltransferase, methods and compositions |
US9242007B2 (en) | 2004-08-26 | 2016-01-26 | Engeneic Molecular Delivery Pty. Ltd. | Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells |
US8669101B2 (en) | 2004-08-26 | 2014-03-11 | Engeneic Molecular Delivery Pty. Ltd. | Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells |
US8735566B2 (en) | 2004-08-26 | 2014-05-27 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells |
US9066982B2 (en) | 2004-08-26 | 2015-06-30 | Engeneic Molecular Delivery Pty Ltd. | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
US8691963B2 (en) | 2004-08-26 | 2014-04-08 | Engeneic Molecular Delivery Pty. Ltd. | Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells |
US10098847B2 (en) | 2004-08-26 | 2018-10-16 | Engeneic Molecular Delivery Pty Ltd | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
US10426736B2 (en) | 2004-08-26 | 2019-10-01 | Engeneic Molecular Delivery Pty. Ltd. | Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells |
US20080299084A1 (en) * | 2004-08-26 | 2008-12-04 | Engeneic Therapy Pty. Ltd. | Bacterially derived intact minicells that encompass plasma free functional nucleic acid for in vivo delivery to mammalian cells |
US10441546B2 (en) | 2004-08-26 | 2019-10-15 | Engenelc Molecular Delivery Pty Ltd | Bacterially derived intact minicells that encompass plasmid free DNA and methods of using the same |
US10383827B2 (en) | 2004-08-26 | 2019-08-20 | Engeneic Molecular Delivery Pty Ltd | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
US20110111041A1 (en) * | 2004-08-26 | 2011-05-12 | EnGenelC Therapy Pty. Ltd. | Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells |
US8956864B2 (en) | 2004-08-26 | 2015-02-17 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells |
EP2386640A2 (en) | 2004-08-26 | 2011-11-16 | EnGeneIC Molecular Delivery Pty Ltd | Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells |
US9730897B2 (en) | 2004-08-26 | 2017-08-15 | Engeneic Molecular Delivery Pty Ltd | Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells |
US20060046273A1 (en) * | 2004-08-27 | 2006-03-02 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for oral fluid |
WO2006024694A2 (en) | 2004-09-03 | 2006-03-09 | Licentia Oy | Peptide inhibitors of hk2 and their use |
EP2343311A2 (en) | 2004-09-03 | 2011-07-13 | Licentia Oy | Peptide inhibitors of HK2 and their use |
EP2246444A1 (en) | 2004-09-14 | 2010-11-03 | The Regents of the University of Colorado, A Body Corporate | Method for treatment with bucindolol based on genetic targeting |
EP2382977A1 (en) | 2004-09-18 | 2011-11-02 | University of Maryland, Baltimore | Therapeutic agents targeting the ncca-atp channel and methods of use thereof |
WO2006034048A2 (en) | 2004-09-18 | 2006-03-30 | University Of Maryland, Baltimore | Therapeutic agents targeting the ncca-atp channel and methods of use thereof |
EP2359832A2 (en) | 2004-09-18 | 2011-08-24 | University of Maryland, Baltimore | Therapeutic agents targeting the NCCA-ATP channel and methods of use thereof |
US7442778B2 (en) | 2004-09-24 | 2008-10-28 | Amgen Inc. | Modified Fc molecules |
US20060140934A1 (en) * | 2004-09-24 | 2006-06-29 | Colin Gegg | Modified Fc molecules |
US20090012272A1 (en) * | 2004-09-24 | 2009-01-08 | Amgen Inc. | Modified Fc molecules |
US7645861B2 (en) | 2004-09-24 | 2010-01-12 | Amgen Inc. | Modified Fc molecules |
US20090022744A1 (en) * | 2004-09-24 | 2009-01-22 | Amgen Inc. | Modified Fc molecules |
US7655765B2 (en) | 2004-09-24 | 2010-02-02 | Amgen Inc. | Modified Fc molecules |
US7750128B2 (en) | 2004-09-24 | 2010-07-06 | Amgen Inc. | Modified Fc molecules |
US7750127B2 (en) | 2004-09-24 | 2010-07-06 | Amgen Inc. | Modified Fc molecules |
US7655764B2 (en) | 2004-09-24 | 2010-02-02 | Amgen Inc. | Modified Fc molecules |
US7662931B2 (en) | 2004-09-24 | 2010-02-16 | Amgen Inc. | Modified Fc molecules |
US8143045B2 (en) | 2004-10-04 | 2012-03-27 | Danisco A/S | Mutant Citrobacter freundii phytase polypeptide |
US9273295B2 (en) | 2004-10-04 | 2016-03-01 | Dupont Nutrition Biosciences Aps | Mutant citrobacter freundii phytase polypeptide |
US20060078951A1 (en) * | 2004-10-08 | 2006-04-13 | Youn Byung S | Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody |
US7390489B2 (en) | 2004-10-08 | 2008-06-24 | Komed Co., Ltd. | Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody |
US20070298145A1 (en) * | 2004-10-18 | 2007-12-27 | Andrei Miasnikov | Enzymes |
US8053221B2 (en) | 2004-10-18 | 2011-11-08 | Danisco A/S | Enzymes |
EP2264156A1 (en) | 2004-10-18 | 2010-12-22 | Danisco A/S | Phytases |
EP2236601A1 (en) | 2004-10-18 | 2010-10-06 | Danisco A/S | Phytases |
WO2006043178A2 (en) | 2004-10-18 | 2006-04-27 | Danisco A/S | Enzymes |
EP2236600A1 (en) | 2004-10-18 | 2010-10-06 | Danisco A/S | Enzymes |
US20090104170A1 (en) * | 2004-11-02 | 2009-04-23 | Richard William Wyatt Childs | Compositions and methods for treating hyperproliferative disorders |
EP1655381A1 (en) | 2004-11-04 | 2006-05-10 | Affymetrix, Inc. (A US Entity) | Nucleic acid labeling methods |
US20090118132A1 (en) * | 2004-11-04 | 2009-05-07 | Roche Molecular Systems, Inc. | Classification of Acute Myeloid Leukemia |
EP2210899A1 (en) | 2004-11-11 | 2010-07-28 | Danisco A/S | pntr transcription factor |
US8809287B2 (en) | 2004-11-15 | 2014-08-19 | Icahn School Of Medicine At Mount Sinai | Compositions and methods for altering Wnt autocrine signaling |
US20090163407A1 (en) * | 2004-11-15 | 2009-06-25 | Mount Sinai School Of Medicine Of New York University | Compositions and methods for altering wnt autocrine signaling |
EP2302072A1 (en) | 2004-11-18 | 2011-03-30 | Eppendorf Array Technologies S.A. | Real time-PCR of targets on a micro-array |
US8288128B2 (en) | 2004-11-18 | 2012-10-16 | Eppendorf Array Technologies S.A. | Real-time quantification of multiple targets on a micro-array |
US20060105354A1 (en) * | 2004-11-18 | 2006-05-18 | Eppendorf Array Technologies S.A. | Real-time quantification of multiple targets on a micro-array |
EP2281841A2 (en) | 2004-12-03 | 2011-02-09 | Schering Corporation | Biomarkers for pre-selection of patients for anti-IGF1R therapy |
EP2283831A2 (en) | 2004-12-03 | 2011-02-16 | Schering Corporation | Biomakers for pre-selection of patients for anti-IGF1R therapy |
US20060134538A1 (en) * | 2004-12-16 | 2006-06-22 | Radu Nora S | Aromatic chalcogen compounds and their use |
US20060217322A1 (en) * | 2004-12-29 | 2006-09-28 | Neal Bricker | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
US20100092999A1 (en) * | 2004-12-29 | 2010-04-15 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
US8034576B2 (en) | 2004-12-29 | 2011-10-11 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
EP3379506A1 (en) | 2004-12-29 | 2018-09-26 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
US8361734B2 (en) | 2004-12-29 | 2013-01-29 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
US10370335B2 (en) | 2004-12-29 | 2019-08-06 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositions and methods related thereto |
WO2006072000A2 (en) | 2004-12-29 | 2006-07-06 | Naturon, Inc. | Xanthurenic acid derivative pharmaceutical compositoins and methods related thereto |
EP2520669A2 (en) | 2005-02-07 | 2012-11-07 | GeneNews Inc. | Mild osteoathritis biomarkers and uses thereof |
US20100047230A1 (en) * | 2005-02-21 | 2010-02-25 | Hellenic Pasteur Institute | Anti her2/neu antibody |
EP2444099A1 (en) | 2005-03-31 | 2012-04-25 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
EP3300739A2 (en) | 2005-03-31 | 2018-04-04 | Agensys, Inc. | Antibodies and related molecules that bind to 161p2f10b proteins |
EP3264094A1 (en) | 2005-04-04 | 2018-01-03 | Biogen MA Inc. | Methods for evaluating an immune response to a therapeutic agent |
US10705095B2 (en) | 2005-04-04 | 2020-07-07 | Biogen Ma Inc. | Methods and products for evaluating an immune response to a therapeutic protein |
EP2645106A2 (en) | 2005-04-04 | 2013-10-02 | Biogen Idec MA Inc. | Methods and products for evaluating an immune response to a therapeutic agent |
US11686734B2 (en) | 2005-04-04 | 2023-06-27 | Biogen Ma Inc. | Methods and products for evaluating an immune response to a therapeutic protein |
WO2006107962A2 (en) | 2005-04-04 | 2006-10-12 | Biogen Idec Ma Inc | Methods and products for evaluating an immune response to a therapeutic protein |
EP3796003A1 (en) | 2005-04-04 | 2021-03-24 | Biogen MA Inc. | Methods for evaluating an immune response to a therapeutic agent |
US10308987B2 (en) | 2005-04-18 | 2019-06-04 | Mdna Life Sciences Inc. | 3.4 kb mitochondrial DNA deletion for use in the detection of cancer |
US10907213B2 (en) | 2005-04-18 | 2021-02-02 | Mdna Life Sciences Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
US11111546B2 (en) | 2005-04-18 | 2021-09-07 | Mdna Life Sciences, Inc. | 3.4 KB mitochondrial DNA deletion for use in the detection of cancer |
US9745632B2 (en) | 2005-04-18 | 2017-08-29 | Mdna Life Sciences Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
EP2339032A1 (en) | 2005-04-18 | 2011-06-29 | Mitomics Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
US8008008B2 (en) | 2005-04-18 | 2011-08-30 | Mitomics Inc. | Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers |
US20060240496A1 (en) * | 2005-04-21 | 2006-10-26 | Lakshmi Anne | Immunogens, derivatives and immunoassay for ethyl glucuronide |
WO2006116727A2 (en) | 2005-04-27 | 2006-11-02 | Dade Rehring Inc. | Compositions and methods for detection of sirolimus |
EP2312315A1 (en) | 2005-05-18 | 2011-04-20 | Novartis AG | Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component |
EP2933265A2 (en) | 2005-06-03 | 2015-10-21 | Amicus Therapeutics, Inc. | Pharmacological chaperones for treating obesity |
EP2425850A2 (en) | 2005-06-15 | 2012-03-07 | The Regents of The University of California | Bispecific single chain FV antibody molecules and methods of use thereof |
EP2711434A1 (en) | 2005-06-20 | 2014-03-26 | Advanced Cell Diagnostics, Inc. | Multiplex detection of nucleic acids |
WO2007001986A2 (en) | 2005-06-20 | 2007-01-04 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
EP2460893A1 (en) | 2005-06-20 | 2012-06-06 | Advanced Cell Diagnostics, Inc. | Multiplex detection of nucleic acids |
EP2500439A1 (en) | 2005-06-20 | 2012-09-19 | Advanced Cell Diagnostics, Inc. | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
WO2007001991A2 (en) | 2005-06-23 | 2007-01-04 | Dade Behring Inc. | Detection of adulterated samples |
US20100068135A1 (en) * | 2005-08-08 | 2010-03-18 | Onconon, Llc | Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility |
US8642330B2 (en) | 2005-08-08 | 2014-02-04 | Onconon, Llc | Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
US11266744B2 (en) | 2005-08-12 | 2022-03-08 | Amgen Inc. | Modified Fc molecules |
EP2425860A1 (en) | 2005-08-12 | 2012-03-07 | Amgen Inc. | Modified Fc molecules |
US9114175B2 (en) | 2005-08-12 | 2015-08-25 | Amgen Inc. | Modified Fc molecules |
US10188740B2 (en) | 2005-08-12 | 2019-01-29 | Amgen Inc. | Modified Fc molecules |
EP3190125A1 (en) | 2005-08-31 | 2017-07-12 | Merck Sharp & Dohme Corp. | Engineered anti-il-23 antibodies |
WO2007027714A2 (en) | 2005-08-31 | 2007-03-08 | Schering Corporation | Engineered anti-il-23 antibodies |
EP2354160A1 (en) | 2005-08-31 | 2011-08-10 | Schering Corporation | Engineered anti-IL-23-antibodies |
US20070059717A1 (en) * | 2005-09-15 | 2007-03-15 | Baylor Research Institute | Systemic lupus erythematosus diagnostic assay |
US7608395B2 (en) | 2005-09-15 | 2009-10-27 | Baylor Research Institute | Systemic lupus erythematosus diagnostic assay |
EP2302079A2 (en) | 2005-09-15 | 2011-03-30 | Baylor Research Institute | Systemic lupus erythematosus diagnostic assay |
US20080274905A1 (en) * | 2005-09-30 | 2008-11-06 | The Trustees Of Columbia University In The City Of New York | Microfluidic cells with parallel arrays of individual dna molecules |
US20070202515A1 (en) * | 2005-10-12 | 2007-08-30 | Pathologica, Llc. | Promac signature application |
EP2319941A2 (en) | 2005-10-21 | 2011-05-11 | GeneNews Inc. | Method and apparatus for correlating levels of biomarker products with disease |
WO2007056352A2 (en) | 2005-11-07 | 2007-05-18 | The Scripps Research Institute | Compositions and methods for controlling tissue factor signaling specificity |
DE212006000071U1 (en) | 2005-11-18 | 2008-07-24 | Board of Regents, The University of Texas System, Austin | Quantification of fusion proteins and their activity as a result of chromosomal translocation |
EP2546359A1 (en) | 2005-12-08 | 2013-01-16 | Novartis AG | Effects of inhibitors of FGFR3 on gene transcription |
US20070134814A1 (en) * | 2005-12-09 | 2007-06-14 | Kajander E O | Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease |
EP2674440A2 (en) | 2005-12-16 | 2013-12-18 | IBC Pharmaceuticals, Inc. | Multivalent immunoglobulin-based bioactive assemblies |
US8318898B2 (en) | 2005-12-23 | 2012-11-27 | Universite De Lausanne | Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of cellular relaxation |
US20090226387A1 (en) * | 2005-12-23 | 2009-09-10 | Partnership & Corp. Technology Transfer | Synthetic peptides for use as inhibitors of neurotransmitter secretion and as inducers of cellular relaxation |
EP2172210A1 (en) | 2005-12-23 | 2010-04-07 | Partnership&Corp. Technology Transfer | Synthetic peptides for use as inhibitors of neurotransmitter secretion |
US20070161007A1 (en) * | 2006-01-11 | 2007-07-12 | Wisconsin Alumni Research Foundation | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use |
US7465544B2 (en) | 2006-01-11 | 2008-12-16 | Wisconsin Alumni Research Foundation | Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use |
US8669345B2 (en) | 2006-01-27 | 2014-03-11 | Biogen Idec Ma Inc. | Nogo receptor antagonists |
US9228015B2 (en) | 2006-01-27 | 2016-01-05 | Biogen Idec Ma Inc. | Nogo receptor antagonists and methods of increasing neurite outgrowth |
EP2526968A2 (en) | 2006-01-27 | 2012-11-28 | Biogen Idec MA Inc. | Nogo receptor antagonists |
WO2007088051A2 (en) | 2006-01-31 | 2007-08-09 | Bayer Schering Pharma Aktiengesellschaft | Modulation of mdl-1 activity for treatment of inflammatory disease |
EP3456331A1 (en) | 2006-02-08 | 2019-03-20 | Genzyme Corporation | Gene therapy for niemann-pick disease type a |
WO2007092563A2 (en) | 2006-02-08 | 2007-08-16 | Genzyme Corporation | Gene therapy for niemann-pick disease type a |
US11292845B2 (en) | 2006-02-28 | 2022-04-05 | Biogen Ma Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
DE102006009516A1 (en) * | 2006-02-28 | 2007-08-30 | Analyticon Biotechnologies Ag | Test device for detecting an analyte in a liquid sample comprises a dry porous support with a reaction zone containing an analyte-selective binder, a biomarker/reporter enzyme complex and a reporter substrate |
DE102006009516B4 (en) * | 2006-02-28 | 2007-12-06 | Analyticon Biotechnologies Ag | Test device, manufacturing method therefor and test method |
US20090061460A1 (en) * | 2006-02-28 | 2009-03-05 | Analyticon Biotechnologies Ag | Test apparatus, production method therefor and test method |
US11333670B2 (en) | 2006-03-03 | 2022-05-17 | Biogen Ma Inc. | Methods of treating inflammatory and autoimmune diseases with natalizumab |
US8114619B2 (en) | 2006-03-21 | 2012-02-14 | The Johns Hopkins University | Methods for diagnosis and optimizing treatment of multiple sclerosis |
US20070232556A1 (en) * | 2006-03-31 | 2007-10-04 | Montine Thomas J | Methods and compositions for the treatment of neurological diseases and disorders |
US8071323B2 (en) | 2006-04-07 | 2011-12-06 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human monoclonal antibodies that bind human insulin like growth factors and their use |
US20100055033A1 (en) * | 2006-04-07 | 2010-03-04 | The Government Of The United States Of America As Represented By The Secretary | Antibody compositions and methods for treatment of neoplastic disease |
WO2007124299A2 (en) | 2006-04-21 | 2007-11-01 | Novartis Ag | Antagonist anti-cd40 antibody pharmaceutical compositions |
US20110065649A1 (en) * | 2006-04-27 | 2011-03-17 | Centre National De La Recherche Scientifique (Cnrs) | Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation |
US8497349B2 (en) | 2006-04-27 | 2013-07-30 | Centre National De La Recherche Scientifique (Cnrs) | Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation |
US9254309B2 (en) | 2006-04-27 | 2016-02-09 | Centre National De La Recherche Scientifique (Cnrs) | Use of multivalent synthetic ligands of surface nucleolin for treating cancer or inflammation |
US20070264665A1 (en) * | 2006-05-09 | 2007-11-15 | Hashen Akhavan-Tafti | Nonseparation assay methods |
US8790871B2 (en) | 2006-05-09 | 2014-07-29 | Musc Foundation For Research Development | Detecting diastolic heart failure by protease and protease inhibitor plasma profiling |
US8377647B2 (en) | 2006-05-09 | 2013-02-19 | Beckman Coulter, Inc. | Nonseparation assay methods |
US7799534B2 (en) | 2006-05-09 | 2010-09-21 | Beckman Coulter, Inc. | Nonseparation assay methods |
US7732153B2 (en) | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
US20100062459A1 (en) * | 2006-06-20 | 2010-03-11 | Siemens Healthcare Diagnostics Inc. | Tacrolimus Standard and Methods of Using Same |
US7642338B2 (en) | 2006-06-20 | 2010-01-05 | Siemens Healthcare Diagnostics Inc. | Tacrolimus standard and methods of using same |
US20070292891A1 (en) * | 2006-06-20 | 2007-12-20 | Wei Tie Q | Tacrolimus standard and methods of using same |
US8153594B2 (en) | 2006-06-20 | 2012-04-10 | Siemens Healthcare Diagnostics Inc. | Tacrolimus standard and methods of using same |
WO2008005429A2 (en) | 2006-07-03 | 2008-01-10 | Charles David Adair | Composition for modulating the expression of cell adhesion molecules |
US20080026394A1 (en) * | 2006-07-11 | 2008-01-31 | Antara Biosciences Inc. | Methods of detecting one or more cancer markers |
US20100015651A1 (en) * | 2006-07-11 | 2010-01-21 | Musc Foundation For Research Development | Predicting Heart Failure Following Myocardial Infarction by Protease and Protease Inhibitor Profiling |
US8445222B2 (en) | 2006-07-11 | 2013-05-21 | Musc Foundation For Research Development | Predicting heart failure following myocardial infarction by protease and protease inhibitor profiling |
WO2008010934A2 (en) | 2006-07-14 | 2008-01-24 | Chemocentryx, Inc. | Triazolyl phenyl benzenesulfonamides |
US20110184747A1 (en) * | 2006-08-09 | 2011-07-28 | Carmen Bozic | Method for distribution of a drug |
EP2774987A1 (en) | 2006-08-17 | 2014-09-10 | Affymetrix, Inc. | Nucleic acid quantitation from tissue slides |
EP2423333A1 (en) | 2006-08-25 | 2012-02-29 | Oncotherapy Science, Inc. | Prognostic markers and therapeutic targets for lung cancer |
EP2423332A1 (en) | 2006-08-25 | 2012-02-29 | Oncotherapy Science, Inc. | Prognostic markers and therapeutic targets for lung cancer |
US20090042209A1 (en) * | 2006-09-01 | 2009-02-12 | Nox Technologies, Inc. | Neoplasia-Specific tNOX Isoforms and Methods |
US8586723B2 (en) | 2006-09-07 | 2013-11-19 | Institut Pasteur | Genomic morse code |
US7985542B2 (en) | 2006-09-07 | 2011-07-26 | Institut Pasteur | Genomic morse code |
US20100041036A1 (en) * | 2006-09-07 | 2010-02-18 | Institut Pasteur | Genomic morse code |
EP3133172A1 (en) | 2006-09-07 | 2017-02-22 | Institut Pasteur | Genomic morse code |
US20080064114A1 (en) * | 2006-09-07 | 2008-03-13 | Institut Pasteur | Genomic morse code |
EP2469283A1 (en) | 2006-09-08 | 2012-06-27 | University of Oxford | Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker. |
US20080085526A1 (en) * | 2006-09-08 | 2008-04-10 | United Therapeutics Corporation | Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers |
US9012162B2 (en) | 2006-09-08 | 2015-04-21 | The Chancellor, Masters And Scholars Of The University Of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers |
EP2469282A1 (en) | 2006-09-08 | 2012-06-27 | University of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers |
US8050516B2 (en) | 2006-09-13 | 2011-11-01 | Fluidigm Corporation | Methods and systems for determining a baseline during image processing |
US8849037B2 (en) | 2006-09-13 | 2014-09-30 | Fluidigm Corporation | Methods and systems for image processing of microfluidic devices |
US8055034B2 (en) | 2006-09-13 | 2011-11-08 | Fluidigm Corporation | Methods and systems for image processing of microfluidic devices |
US20080075322A1 (en) * | 2006-09-13 | 2008-03-27 | Fluidigm Corporation | Methods and systems for determining a baseline during image processing |
US20080075380A1 (en) * | 2006-09-13 | 2008-03-27 | Fluidigm Corporation | Methods and systems for image processing of microfluidic devices |
US8600168B2 (en) | 2006-09-13 | 2013-12-03 | Fluidigm Corporation | Methods and systems for image processing of microfluidic devices |
WO2008043566A2 (en) | 2006-10-11 | 2008-04-17 | Janssen Pharmaceutica N.V. | Compositions and methods for treating and diagnosing irritable bowel syndrome |
US20100222228A1 (en) * | 2006-10-11 | 2010-09-02 | Janssen Pharmaceutica N.V. | Compositions and methods for treating and diagnosing irritable bowel syndrome |
US20080214407A1 (en) * | 2006-10-12 | 2008-09-04 | Eppendorf Array Technologies S.A. | Method and system for quantification of a target compound obtained from a biological sample upon chips |
EP2426199A2 (en) | 2006-10-20 | 2012-03-07 | Danisco US Inc. | Polyol oxidases |
US20080305512A1 (en) * | 2006-10-26 | 2008-12-11 | Mattingly Phillip G | Assay for cardiac troponin autoantibodies |
WO2008051761A2 (en) | 2006-10-26 | 2008-05-02 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
US8357495B2 (en) | 2006-10-26 | 2013-01-22 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
US8173382B2 (en) | 2006-10-26 | 2012-05-08 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
US20090246800A1 (en) * | 2006-10-26 | 2009-10-01 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
US20100311079A1 (en) * | 2006-10-26 | 2010-12-09 | Abbott Laboratories | Assay for cardiac troponin autoantibodies |
EP2402752A2 (en) | 2006-10-27 | 2012-01-04 | Janssen Pharmaceutica, N.V. | A method for pharmacologically profiling compounds |
EP2407783A1 (en) | 2006-10-27 | 2012-01-18 | Janssen Pharmaceutica, N.V. | A method for pharmacologically profiling compounds |
EP2450456A2 (en) | 2006-11-02 | 2012-05-09 | Yale University | Assessment of oocyte competence |
US8293684B2 (en) | 2006-11-29 | 2012-10-23 | Exiqon | Locked nucleic acid reagents for labelling nucleic acids |
US20090023594A1 (en) * | 2006-11-29 | 2009-01-22 | Exiqon A/S | Reagents for labelling nucleic acids and uses thereof |
US8473216B2 (en) | 2006-11-30 | 2013-06-25 | Fluidigm Corporation | Method and program for performing baseline correction of amplification curves in a PCR experiment |
WO2008067547A2 (en) | 2006-11-30 | 2008-06-05 | Research Development Foundation | Improved immunoglobulin libraries |
US20080129736A1 (en) * | 2006-11-30 | 2008-06-05 | Fluidigm Corporation | Method and apparatus for biological sample analysis |
WO2008076321A1 (en) | 2006-12-14 | 2008-06-26 | Schering Corporation | Engineered anti-tslp antibody |
EP2628752A1 (en) | 2006-12-14 | 2013-08-21 | Merck Sharp & Dohme Corp. | Engineered anti-TSLP antibody |
EP2487187A2 (en) | 2007-01-04 | 2012-08-15 | Institute for Research in Biomedicine | Human cytomegalovirus neutralising antibodies and use thereof |
US8506499B2 (en) | 2007-01-04 | 2013-08-13 | Musc Foundation For Research Development | Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling |
WO2008084410A2 (en) | 2007-01-04 | 2008-07-17 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
US20110009861A1 (en) * | 2007-01-04 | 2011-01-13 | Music Foundation For Research Development | Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling |
EP2860189A2 (en) | 2007-01-04 | 2015-04-15 | Institute for Research in Biomedicine | Human cytomegalovirus neutralising antibodies and use thereof |
US8642295B2 (en) | 2007-01-11 | 2014-02-04 | Erasmus University Medical Center | Circular chromosome conformation capture (4C) |
US20100062947A1 (en) * | 2007-01-11 | 2010-03-11 | Erasmus University Medical Center | Circular chromosome conformation capture (4c) |
EP3103451A1 (en) | 2007-01-12 | 2016-12-14 | University of Maryland, Baltimore | Targetting ncca-atp channel for organ protection following ischemic episode |
US20100081169A1 (en) * | 2007-01-25 | 2010-04-01 | Marc Kolkman | Production of a lipid acyltransferase from transformed bacillus licheniformis cells |
US7960150B2 (en) | 2007-01-25 | 2011-06-14 | Danisco A/S | Production of a lipid acyltransferase from transformed Bacillus licheniformis cells |
EP2405007A1 (en) | 2007-01-25 | 2012-01-11 | Danisco A/S | Production of a lipid acyltransferase from transformed bacillus cells |
EP2450702A2 (en) | 2007-01-26 | 2012-05-09 | University Of Louisville Research Foundation, Inc. | Methods of detecting autoantibodies for diagnosing and characterizing disorders |
WO2008092164A2 (en) | 2007-01-26 | 2008-07-31 | University Of Louisville Research Foundation, Inc. | Methods of detecting autoantibodies for diagnosing and characterizing disorders |
US8143046B2 (en) | 2007-02-07 | 2012-03-27 | Danisco Us Inc., Genencor Division | Variant Buttiauxella sp. phytases having altered properties |
US20090098249A1 (en) * | 2007-02-07 | 2009-04-16 | Cervin Marguerite A | Variant Buttiauxella sp. Phytases having altered properties |
US9522880B2 (en) | 2007-02-16 | 2016-12-20 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
US11525835B2 (en) | 2007-02-16 | 2022-12-13 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
US11402395B2 (en) | 2007-02-16 | 2022-08-02 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
US20080219995A1 (en) * | 2007-02-16 | 2008-09-11 | Konkuk University Industrial Cooperation Corp. | Il-32 monoclonal antibodies and uses thereof |
US7641904B2 (en) | 2007-02-16 | 2010-01-05 | Konkuk University Industrial Cooperation Corp. | IL-32 monoclonal antibodies and uses thereof |
US10203345B2 (en) | 2007-02-16 | 2019-02-12 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
US11867705B2 (en) | 2007-02-16 | 2024-01-09 | Ark Diagnostics, Inc. | Compounds and methods for use in detecting gabapentin |
EP2426144A1 (en) | 2007-02-23 | 2012-03-07 | Schering Corporation | Engineered anti-IL-23p19 antibodies |
EP2426145A1 (en) | 2007-02-23 | 2012-03-07 | Schering Corporation | Engineered anti-IL-23p19 antibodies |
EP2395025A1 (en) | 2007-02-28 | 2011-12-14 | Schering Corporation | Engineered Anti-IL-23R Antibodies |
US20080220498A1 (en) * | 2007-03-06 | 2008-09-11 | Cervin Marguerite A | Variant Buttiauxella sp. phytases having altered properties |
WO2008110006A1 (en) | 2007-03-12 | 2008-09-18 | Miraculins Inc. | Biomarkers of prostate cancer and uses thereof |
EP3205724A1 (en) | 2007-03-30 | 2017-08-16 | EnGeneIC Molecular Delivery Pty Ltd. | Bacterially derived, intact minicells encompassing regulatory rna |
EP3564372A1 (en) | 2007-03-30 | 2019-11-06 | EnGeneIC Molecular Delivery Pty Ltd. | Bacterially derived, intact minicells encompassing regulatory rna |
EP2532746A2 (en) | 2007-03-30 | 2012-12-12 | EnGeneIC Molecular Delivery Pty Ltd. | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
EP2865755A2 (en) | 2007-03-30 | 2015-04-29 | EnGeneIC Molecular Delivery Pty Ltd | Bacterially derived, intact minicells encompassing regulatory RNA |
WO2008124670A2 (en) | 2007-04-06 | 2008-10-16 | Becton, Dickinson And Company | Compositions and methods for the identification of a carbapenemase gene |
US20100255004A1 (en) * | 2007-04-13 | 2010-10-07 | Dana Farber Cancer Institute | Receptor tyrosine kinase profiling |
US11008620B2 (en) | 2007-04-13 | 2021-05-18 | The General Hospital Corporation | Methods for treating cancer resistant to ErbB therapeutics |
US8715665B2 (en) | 2007-04-13 | 2014-05-06 | The General Hospital Corporation | Methods for treating cancer resistant to ErbB therapeutics |
EP2851091A1 (en) | 2007-04-13 | 2015-03-25 | Dana-Farber Cancer Institute, Inc. | Methods for treating cancer resistant to ERBB therapeutics |
US20100261153A1 (en) * | 2007-04-16 | 2010-10-14 | Scholl David R | Methods For Direct Fluorescent Antibody Virus Detection In Liquids |
WO2008137475A2 (en) | 2007-05-01 | 2008-11-13 | Research Development Foundation | Immunoglobulin fc libraries |
US8795682B2 (en) | 2007-05-02 | 2014-08-05 | Emory University | Virus-like particles comprising chimeric human immunodeficiency virus (HIV)/mouse mammary tumor virus (MMTV) envelopes |
US20100196419A1 (en) * | 2007-05-02 | 2010-08-05 | Compans Richard W | Enhancement of glycoprotein incorporation into virus-like particles |
WO2009038847A1 (en) | 2007-06-22 | 2009-03-26 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl)arylsulfonamides and n-(2-(hetaryl)hetaryl)arylsulfonamides |
US8198309B2 (en) | 2007-06-22 | 2012-06-12 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl)hetaryl arylsulfonamides |
US7776877B2 (en) | 2007-06-22 | 2010-08-17 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides |
US20100331302A1 (en) * | 2007-06-22 | 2010-12-30 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and n-(2-(hetaryl)hetaryl arylsulfonamides |
US9409909B2 (en) | 2007-06-22 | 2016-08-09 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl)arylsulfonamides and N-(2-(hetaryl)hetaryl)arylsulfonamides |
US8835468B2 (en) | 2007-06-22 | 2014-09-16 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl)arylsulfonamides and n-(2-(hetaryl)hetaryl) arylsulfonamides |
US20090005410A1 (en) * | 2007-06-22 | 2009-01-01 | Chemocentryx, Inc. | N-(2-(hetaryl)aryl) arylsulfonamides and n-(2-(hetaryl) hetaryl arylsulfonamides |
US20100221272A1 (en) * | 2007-06-28 | 2010-09-02 | University Of Saskatchewan | Immunomodulatory compositions and methods for treating disease with modified host defense peptides |
US9102754B2 (en) | 2007-06-28 | 2015-08-11 | University Of Saskatchewan | Immunomodulatory compositions and methods for treating disease with modified host defense peptides |
US9745312B2 (en) | 2007-07-12 | 2017-08-29 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US20090233946A1 (en) * | 2007-07-12 | 2009-09-17 | Antoni Krasinski | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as ccr2 modulators for the treatment of inflammation |
US10208050B2 (en) | 2007-07-12 | 2019-02-19 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US7884110B2 (en) | 2007-07-12 | 2011-02-08 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US8546408B2 (en) | 2007-07-12 | 2013-10-01 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US10899765B2 (en) | 2007-07-12 | 2021-01-26 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US9394307B2 (en) | 2007-07-12 | 2016-07-19 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation |
US10640762B2 (en) | 2007-07-26 | 2020-05-05 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
EP3293269A1 (en) | 2007-08-03 | 2018-03-14 | MUSC Foundation For Research Development | Human monoclonal antibodies and methods for producing the same |
EP4036572A1 (en) | 2007-08-06 | 2022-08-03 | Siemens Healthcare Diagnostics Inc. | Methods for detection of immunosuppressant drugs |
WO2009021054A2 (en) | 2007-08-06 | 2009-02-12 | Orion Genomics Llc | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene |
EP2700723A2 (en) | 2007-08-06 | 2014-02-26 | Orion Genomics, LLC | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene |
EP2952588A1 (en) | 2007-08-06 | 2015-12-09 | Orion Genomics, LLC | Single nucleotide polymorphism in igf2 for determining the allele-specific expression of the igf2 gene |
WO2009032477A2 (en) | 2007-08-08 | 2009-03-12 | The Board Of Regents Of The University Of Texas System | Vegfr-1/nrp-1 targeting peptides |
US8945928B2 (en) | 2007-08-12 | 2015-02-03 | Kerry B Gunning | Microarray system with improved sequence specificity |
US20090143243A1 (en) * | 2007-08-12 | 2009-06-04 | Gunning Kerry B | Microarray system with improved sequence specificity |
US8067164B2 (en) | 2007-08-12 | 2011-11-29 | Integrated Dna Technologies, Inc. | Microarray system with improved sequence specificity |
US20090136916A1 (en) * | 2007-08-13 | 2009-05-28 | Trustees Of Tufts College | Methods and microarrays for detecting enteric viruses |
US8652809B2 (en) | 2007-08-17 | 2014-02-18 | Dupont Nutrition Biosciences Aps | Method for producing ultra-heat treatment milk |
US20100215803A1 (en) * | 2007-08-17 | 2010-08-26 | Niels Erik Larsen | Process |
EP2511708A1 (en) | 2007-10-05 | 2012-10-17 | Affymetrix, Inc. | Highly multiplexed particle-based assays |
US8138316B2 (en) | 2007-10-15 | 2012-03-20 | Idexx Laboratories, Inc. | Feline pancreatic lipase |
US20100267131A1 (en) * | 2007-10-15 | 2010-10-21 | Idexx Laboratories, Inc. | Feline Pancreatic Lipase |
EP2230255A1 (en) | 2007-10-15 | 2010-09-22 | IDEXX Laboratories, Inc. | Feline pancreatic lipase |
US20090098576A1 (en) * | 2007-10-15 | 2009-04-16 | Idexx Laboratories, Inc. | Feline Pancreatic Lipase |
US7771960B2 (en) | 2007-10-15 | 2010-08-10 | Idexx Laboratories, Inc. | Feline pancreatic lipase |
EP2050826A2 (en) | 2007-10-16 | 2009-04-22 | Roche Diagnostics GmbH | Reagents and methods for detecting neisseria gonorrhoeae |
US20100240070A1 (en) * | 2007-11-07 | 2010-09-23 | Beckman Coulter, Inc. | Nonseparation Assay Methods Using Peroxide Generating Enzymes |
WO2009079374A1 (en) | 2007-12-14 | 2009-06-25 | Siemens Healthcare Diagnostics Inc. | Methods for detection of hydrophobic drugs |
EP2944649A1 (en) | 2008-01-10 | 2015-11-18 | Research Development Foundation | Vaccines and diagnostics for the ehrlichioses |
EP3103467A1 (en) | 2008-02-07 | 2016-12-14 | Cornell University | Methods for preventing or treating insulin resistance |
EP3622963A1 (en) | 2008-02-07 | 2020-03-18 | Cornell University | Methods for preventing or treating insulin resistance |
EP3441079A1 (en) | 2008-02-07 | 2019-02-13 | Cornell University | Methods for preventing or treating insulin resistance |
EP2712620A1 (en) | 2008-02-07 | 2014-04-02 | Cornell University | Methods for Preventing or Treating Insulin Resistance |
EP2902036A1 (en) | 2008-02-07 | 2015-08-05 | Cornell University | Methods for preventing or treating insulin resistance |
EP3272353A1 (en) | 2008-02-07 | 2018-01-24 | Cornell University | Methods for preventing or treating insulin resistance |
EP2679599A1 (en) | 2008-02-20 | 2014-01-01 | Amgen Inc. | Antibodies directed to Angiopoietin-1 and Angiopoietin-2 and use thereof |
US20090311695A1 (en) * | 2008-03-12 | 2009-12-17 | Talat Nasim | Method |
US20110172113A1 (en) * | 2008-03-28 | 2011-07-14 | Mitomics Inc. | Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor |
US8715960B2 (en) | 2008-03-28 | 2014-05-06 | Mitomics Inc. | Aberrant mitochondrial DNA, associated fusion transcripts and translation products and hybridization probes therefor |
US10266899B2 (en) | 2008-03-28 | 2019-04-23 | Mdna Life Sciences Inc. | Aberrant mitochondrial DNA, associated fusion transcripts and hybridization probes therefor |
EP2107125A1 (en) | 2008-03-31 | 2009-10-07 | Eppendorf Array Technologies SA (EAT) | Real-time PCR of targets on a micro-array |
US20110171346A1 (en) * | 2008-04-18 | 2011-07-14 | Spaangner Christiansen Liv | Process |
US20090269780A1 (en) * | 2008-04-23 | 2009-10-29 | Luminex Corporation | Method for Creating a Standard for Multiple Analytes Found in a Starting Material of Biological Origin |
WO2009132124A2 (en) | 2008-04-24 | 2009-10-29 | The Trustees Of Columbia University In The City Of New York | Geometric patterns and lipid bilayers for dna molecule organization and uses thereof |
US20110136676A1 (en) * | 2008-04-24 | 2011-06-09 | Greene Eric C | Geometric patterns and lipid bilayers for dna molecule organization and uses thereof |
US9255289B2 (en) | 2008-04-24 | 2016-02-09 | The Trustees Of Columbia University In The City Of New York | Geometric patterns and lipid bilayers for DNA molecule organization and uses thereof |
US8791232B2 (en) | 2008-04-30 | 2014-07-29 | Dupont Nutrition Biosciences Aps | Proteins |
US9243030B2 (en) | 2008-05-22 | 2016-01-26 | Centre National De La Recherche Scientifique (Cnrs) | Optically pure compounds for improved therapeutic efficiency |
US20110201559A1 (en) * | 2008-05-22 | 2011-08-18 | Centre National De La Recherche Scientifique (Cnrs) | New Optically Pure Compounds for Improved Therapeutic Efficiency |
EP3178845A1 (en) | 2008-07-16 | 2017-06-14 | Institute for Research in Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
EP2960250A1 (en) | 2008-07-16 | 2015-12-30 | Institute for Research in Biomedicine | Human cytomegalovirus neutralising antibodies and use thereof |
EP3009449A1 (en) | 2008-07-16 | 2016-04-20 | Institute for Research in Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
US8871207B2 (en) | 2008-07-25 | 2014-10-28 | Humabs, LLC | Neutralizing anti-influenza A virus antibodies and uses thereof |
US20100086555A1 (en) * | 2008-07-25 | 2010-04-08 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
US20100080813A1 (en) * | 2008-07-25 | 2010-04-01 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
US8685402B2 (en) | 2008-07-25 | 2014-04-01 | Institute For Research In Biomedicine | Neutralizing anti-influenza A virus antibodies and uses thereof |
US9340603B2 (en) | 2008-07-25 | 2016-05-17 | Institute For Research In Biomedicine | Neutralizing anti-influenza A virus antibodies and uses thereof |
US10745744B2 (en) | 2008-09-25 | 2020-08-18 | University Of Massachusetts | HiC: method of identifying interactions between genomic loci |
US9434985B2 (en) | 2008-09-25 | 2016-09-06 | University Of Massachusetts | Methods of identifying interactions between genomic loci |
US9708648B2 (en) | 2008-09-25 | 2017-07-18 | University Of Massachusetts | HiC: method of identifying interactions between genomic loci |
US11231424B2 (en) | 2008-10-24 | 2022-01-25 | Ark Diagnostics, Inc. | Levetiracetam immunoassays |
WO2010054328A2 (en) | 2008-11-07 | 2010-05-14 | Research Development Foundation | Compositions and methods for the inhibition of cripto/grp78 complex formation and signaling |
WO2010065437A1 (en) | 2008-12-03 | 2010-06-10 | Research Development Foundation | Modulation of olfml-3 mediated angiogenesis |
US8445637B2 (en) | 2008-12-05 | 2013-05-21 | Abraxis Bioscience, Llc | SPARC binding peptides and uses thereof |
US8821836B2 (en) | 2008-12-05 | 2014-09-02 | Abraxis Bioscience, Llc | SPARC binding peptides and uses thereof |
US9295733B2 (en) | 2008-12-05 | 2016-03-29 | Abraxis Bioscience, Llc | SPARC binding ScFcs |
US9314537B2 (en) | 2008-12-05 | 2016-04-19 | Abraxis Bioscience, Llc | SPARC binding ScFcs |
US8809507B2 (en) | 2008-12-05 | 2014-08-19 | Vuong Trieu | SPARC binding ScFvs |
US9308279B2 (en) | 2008-12-05 | 2016-04-12 | Abraxis Biosciences, Llc | SPARC binding ScFvs |
US10053504B2 (en) | 2008-12-05 | 2018-08-21 | Abraxis Bioscience, Llc | SPARC binding ScFvs |
EP3059247A1 (en) | 2008-12-05 | 2016-08-24 | Abraxis BioScience, LLC | Sparc binding peptides and uses thereof |
WO2010066252A1 (en) | 2008-12-09 | 2010-06-17 | Dako Denmark A/S | Method for evaluating pre-treatment |
WO2010068757A1 (en) | 2008-12-12 | 2010-06-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions |
EP3301446A1 (en) | 2009-02-11 | 2018-04-04 | Caris MPI, Inc. | Molecular profiling of tumors |
EP2955234A1 (en) | 2009-02-11 | 2015-12-16 | Orion Genomics, LLC | Combinations of polymorphisms for determining allele-specific expression of igf2 |
WO2010093820A2 (en) | 2009-02-11 | 2010-08-19 | Orion Genomics Llc | Combinations of polymorphisms for determining allele-specific expression of igf2 |
EP3722810A2 (en) | 2009-02-11 | 2020-10-14 | Caris MPI, Inc. | Molecular profiling of tumors |
WO2010096658A1 (en) | 2009-02-19 | 2010-08-26 | The Cleveland Clinic Foundation | Corin as a marker for heart failure |
CN102348980A (en) * | 2009-03-12 | 2012-02-08 | 西门子医疗保健诊断公司 | Immunoassays employing non-particulate chemiluminescent reagent |
US9347947B2 (en) | 2009-03-12 | 2016-05-24 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
RU2559581C2 (en) * | 2009-03-12 | 2015-08-10 | Сименс Хелткеа Дайагностикс Инк. | Immunologic research with application of non-dispersible chemiluminiscent reagents |
CN102348980B (en) * | 2009-03-12 | 2015-05-27 | 西门子医疗保健诊断公司 | Immunoassays employing non-particulate chemiluminescent reagent |
WO2010104683A1 (en) * | 2009-03-12 | 2010-09-16 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
US20100233725A1 (en) * | 2009-03-12 | 2010-09-16 | Siemens Healthcare Diagnostics Inc., A Corporation Of California | Immunoassays employing non-particulate chemiluminescent reagent |
US9720004B2 (en) | 2009-03-12 | 2017-08-01 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
US20100240065A1 (en) * | 2009-03-18 | 2010-09-23 | Boehringer Ingelheim International Gmbh | Prolyl Hydroxylase Compositions and Methods of Use Thereof |
US8481698B2 (en) | 2009-03-19 | 2013-07-09 | The President And Fellows Of Harvard College | Parallel proximity ligation event analysis |
US20100240101A1 (en) * | 2009-03-19 | 2010-09-23 | Massachusetts Institute Of Technology | Parallel Proximity Ligation Event Analysis |
WO2010126670A2 (en) | 2009-03-27 | 2010-11-04 | Gojo Industries, Inc. | Compositions and methods for screening and using compounds antagonizing spore-surface interactions |
US20100291100A1 (en) * | 2009-03-27 | 2010-11-18 | Gojo Industries, Inc. | Compositions And Methods For Screening And Using Compounds Antagonizing Spore-Surface Interactions |
WO2010115261A1 (en) | 2009-03-27 | 2010-10-14 | Genesis Genomics Inc. | Aberrant mitochondrial dna, associated fusion transcripts and translation products and hybridization probes therefor |
US10088481B2 (en) | 2009-04-16 | 2018-10-02 | Diagnostic Hybrids, Inc. | Methods for liquid direct fluorescent antibody intracellular virus detection |
US8975016B2 (en) | 2009-04-16 | 2015-03-10 | Diagnostic Hybrids, Inc. | Methods for direct fluorescent antibody virus detection in liquids |
US9447467B2 (en) | 2009-04-21 | 2016-09-20 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
US8940519B2 (en) | 2009-04-24 | 2015-01-27 | Dupont Nutrition Biosciences Aps | Method of producing a lipolytic enzyme |
US9040667B2 (en) | 2009-05-01 | 2015-05-26 | Dako Denmark A/S | Antibody cocktail |
US9778262B2 (en) | 2009-05-01 | 2017-10-03 | Dako Denmark A/S | Antibody cocktail |
US20100291602A1 (en) * | 2009-05-14 | 2010-11-18 | University Of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers |
EP2799876A2 (en) | 2009-05-14 | 2014-11-05 | The Chancellors, Masters and Scholars of the University of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers |
US8889364B2 (en) | 2009-05-14 | 2014-11-18 | The Chancellor, Masters And Scholars Of The University Of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers |
WO2010134035A1 (en) | 2009-05-19 | 2010-11-25 | Danisco A/S | Use |
WO2011019423A2 (en) | 2009-05-20 | 2011-02-17 | Schering Corporation | Modulation of pilr receptors to treat microbial infections |
WO2010141421A1 (en) | 2009-06-02 | 2010-12-09 | The Board Of Regents Of The University Of Texas System | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases |
WO2010150213A1 (en) | 2009-06-25 | 2010-12-29 | Danisco A/S | Protein |
WO2011002834A2 (en) | 2009-07-01 | 2011-01-06 | American Type Culture Collection | Compositions and methods for diagnosis and treatment of type 1 diabetes |
US20110165595A1 (en) * | 2009-07-13 | 2011-07-07 | Catanzaro Brian E | Apparatus and methods for processing a whole blood sample |
WO2011008780A1 (en) | 2009-07-13 | 2011-01-20 | Accumetrics, Inc. | Apparatus and methods for processing a whole blood sample |
US10047357B2 (en) | 2009-07-17 | 2018-08-14 | Bioatla, Llc | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
EP3636759A1 (en) | 2009-07-17 | 2020-04-15 | BioAtla LLC | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
EP3042957A1 (en) | 2009-07-17 | 2016-07-13 | Bioatla LLC | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
US8859467B2 (en) | 2009-07-17 | 2014-10-14 | Bioatla, Llc | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
EP3406717A1 (en) | 2009-07-17 | 2018-11-28 | Bioatla LLC | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
US10106788B2 (en) | 2009-07-17 | 2018-10-23 | Bioatla, Llc | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
EP2907873A1 (en) | 2009-07-17 | 2015-08-19 | Bioatla LLC | Simulataneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
US10920216B2 (en) | 2009-07-17 | 2021-02-16 | Bioatla, Inc. | Simultaneous, integrated selection and evolution of antibody/protein performance and expression in production hosts |
EP3023438A1 (en) | 2009-09-03 | 2016-05-25 | Merck Sharp & Dohme Corp. | Anti-gitr antibodies |
WO2011038403A1 (en) | 2009-09-28 | 2011-03-31 | Yuling Luo | Methods of detecting nucleic acid sequences with high specificity |
WO2011044186A1 (en) | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Human single-chain t cell receptors |
US10464987B2 (en) | 2009-10-06 | 2019-11-05 | Abbvie Inc. | Human single-chain T cell receptors |
US9726672B2 (en) | 2009-10-11 | 2017-08-08 | Biogen Ma Inc. | Anti-VLA-4 related assays |
US10302654B2 (en) | 2009-10-11 | 2019-05-28 | Biogen Ma Inc. | Anti-VLA-4 related assays |
US9377458B2 (en) | 2009-10-11 | 2016-06-28 | Biogen Ma Inc. | Anti-VLA-4 related assays |
US11280793B2 (en) | 2009-10-11 | 2022-03-22 | Biogen Ma Inc. | Anti-VLA-4 related assays |
EP3349010A1 (en) | 2009-10-11 | 2018-07-18 | Biogen MA Inc. | Anti-vla-4 related assays |
WO2011044553A1 (en) | 2009-10-11 | 2011-04-14 | Biogen Idec Ma Inc. | Anti-vla-4 related assays |
WO2011056688A2 (en) | 2009-10-27 | 2011-05-12 | Caris Life Sciences, Inc. | Molecular profiling for personalized medicine |
US8592151B2 (en) | 2009-11-17 | 2013-11-26 | Musc Foundation For Research Development | Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids |
WO2011061657A1 (en) | 2009-11-17 | 2011-05-26 | Danisco A/S | Method |
EP3037435A1 (en) | 2009-11-17 | 2016-06-29 | MUSC Foundation For Research Development | Human monoclonal antibodies to human nucleolin |
US10385128B2 (en) | 2009-11-17 | 2019-08-20 | Musc Foundation For Research Development | Nucleolin antibodies |
US20110117560A1 (en) * | 2009-11-17 | 2011-05-19 | Musc Foundation For Research Development | ASSESSING LEFT VENTRICULAR REMODELING VIA TEMPORAL DETECTION AND MEASUREMENT OF microRNA IN BODY FLUIDS |
US9260517B2 (en) | 2009-11-17 | 2016-02-16 | Musc Foundation For Research Development | Human monoclonal antibodies to human nucleolin |
WO2011063198A2 (en) | 2009-11-20 | 2011-05-26 | St. Jude Children's Research Hospital | Methods and compositions for modulating the activity of the interleukin-35 receptor complex |
US10900962B2 (en) | 2009-11-24 | 2021-01-26 | Sienna Cancer Diagnostics Inc. | Molecular nets and devices for capturing analytes including exosomes |
US20110129818A1 (en) * | 2009-12-02 | 2011-06-02 | Abbott Laboratories | ASSAY FOR CARDIAC TROPONIN-T (cTnT) |
WO2011068681A1 (en) | 2009-12-02 | 2011-06-09 | Abbott Laboratories | ASSAY FOR CARDIAC TROPONIN-T (cTnT) |
US20110129854A1 (en) * | 2009-12-02 | 2011-06-02 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
US8835120B2 (en) | 2009-12-02 | 2014-09-16 | Abbott Laboratories | Assay for cardiac troponin-T (cTnT) |
US8652788B2 (en) | 2009-12-02 | 2014-02-18 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
US20110136103A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
WO2011068676A1 (en) | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
US8183002B2 (en) | 2009-12-03 | 2012-05-22 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
US8574858B2 (en) | 2009-12-03 | 2013-11-05 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
WO2011068680A1 (en) | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Assay for diagnosis of cardiac myocyte damage |
US8304201B2 (en) | 2009-12-03 | 2012-11-06 | Abbott Laboratories | Autoantibody enhanced immunoassays and kits |
US20110136141A1 (en) * | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
WO2011084357A1 (en) | 2009-12-17 | 2011-07-14 | Schering Corporation | Modulation of pilr to treat immune disorders |
WO2011076881A1 (en) | 2009-12-22 | 2011-06-30 | Arabian Gulf University | Mutant ldl receptor gene |
US11287423B2 (en) | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
US10444234B2 (en) | 2010-01-11 | 2019-10-15 | Biogen Ma Inc. | Assay for JC virus antibodies |
EP4152004A1 (en) | 2010-01-11 | 2023-03-22 | Biogen MA Inc. | Assay for jc virus antibodies |
US9316641B2 (en) | 2010-01-11 | 2016-04-19 | Biogen Ma Inc. | Assay for JC virus antibodies |
EP3339865A1 (en) | 2010-01-11 | 2018-06-27 | Biogen MA Inc. | Assay for jc virus antibodies |
WO2011092700A1 (en) | 2010-01-27 | 2011-08-04 | Yeda Research And Development Co. Ltd. | Antibodies that inhibit metalloproteins |
EP3216805A1 (en) | 2010-01-27 | 2017-09-13 | Yeda Research and Development Co. Ltd | Antibodies that inhibit metalloproteins |
WO2011094669A1 (en) | 2010-01-29 | 2011-08-04 | Advanced Cell Diagnostics, Inc. | Methods of in situ detection of nucleic acids |
WO2011096926A1 (en) | 2010-02-03 | 2011-08-11 | Massachusetts Institute Of Technology | Methods for preparing sequencing libraries |
US20110189677A1 (en) * | 2010-02-03 | 2011-08-04 | Massachusetts Institute Of Technology | Methods For Preparing Sequencing Libraries |
US8574832B2 (en) | 2010-02-03 | 2013-11-05 | Massachusetts Institute Of Technology | Methods for preparing sequencing libraries |
WO2011097627A1 (en) | 2010-02-08 | 2011-08-11 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 161p2f10b proteins |
EP3395361A1 (en) | 2010-02-08 | 2018-10-31 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 161p2f10b proteins |
WO2011114251A1 (en) | 2010-03-18 | 2011-09-22 | Danisco A/S | Foodstuff |
WO2011127150A2 (en) | 2010-04-06 | 2011-10-13 | Massachusetts Institute Of Technology | Gene-expression profiling with reduced numbers of transcript measurements |
US9125931B2 (en) | 2010-04-06 | 2015-09-08 | Massachusetts Institute Of Technology | Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers |
US9528998B2 (en) | 2010-04-16 | 2016-12-27 | Abbott Laboratories | Methods and reagents for diagnosing rheumatoid arthrtis |
WO2011140234A1 (en) | 2010-05-07 | 2011-11-10 | Abbott Laboratories | Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor |
WO2011146479A1 (en) | 2010-05-18 | 2011-11-24 | The Texas A&M University System | Method and composition for the diagnosis and monitoring of inflammatory diseases |
WO2011163340A1 (en) | 2010-06-25 | 2011-12-29 | Siemens Healthcare Diagnostics Inc. | Reduction in false results in assay measurements |
WO2012006056A2 (en) | 2010-06-29 | 2012-01-12 | Oregon Health & Science University | Ccr6 as a biomarker of alzheimer's disease |
WO2012004759A2 (en) | 2010-07-08 | 2012-01-12 | Danisco A/S | Method |
EP2407242A1 (en) | 2010-07-13 | 2012-01-18 | Dublin City University | Direct clone analysis and selection technology |
WO2012007537A1 (en) | 2010-07-13 | 2012-01-19 | Dublin City University | Direct clone analysis and selection technology |
WO2012009627A2 (en) | 2010-07-16 | 2012-01-19 | Vanderbilt University | Low resource processor using surface tension valves for extracting, concentrating and detecting molecular species |
EP3435087A1 (en) | 2010-07-16 | 2019-01-30 | Bioatla LLC | Novel methods of protein evolution |
KR20130090892A (en) | 2010-07-23 | 2013-08-14 | 루미넥스 코포레이션 | Co-coupling to control reactivity of reagents in immunoassays |
WO2012012748A2 (en) | 2010-07-23 | 2012-01-26 | Luminex Corporation | Co-coupling to control reactivity of reagents in immunoassays |
US9120862B2 (en) | 2010-07-26 | 2015-09-01 | Abbott Laboratories | Antibodies relating to PIVKA-II and uses thereof |
WO2012018476A1 (en) | 2010-07-26 | 2012-02-09 | Abbott Laboratories | Antibodies relating to pivka-ii and uses thereof |
WO2012019012A1 (en) | 2010-08-04 | 2012-02-09 | Idexx Laboratories, Inc. | Detection of degradation products of canine nt-probnp |
US8778699B2 (en) | 2010-08-04 | 2014-07-15 | Idexx Laboratories, Inc. | Detection of degradation products of canine NT-proBNP |
WO2012024416A1 (en) | 2010-08-20 | 2012-02-23 | Siemens Healthcare Diagnostics Inc. | Assay for analytes using multiple receptors |
WO2012040168A2 (en) | 2010-09-20 | 2012-03-29 | Advanced Cell Diagnostics, Inc. | Biomarkers for differentiating melanoma from benign nevus in the skin |
EP3409287A1 (en) | 2010-09-29 | 2018-12-05 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
WO2012047724A1 (en) | 2010-09-29 | 2012-04-12 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
EP3903812A1 (en) | 2010-09-29 | 2021-11-03 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
US9487559B2 (en) | 2010-10-04 | 2016-11-08 | Elro Pharma Sarl | Compositions comprising multivalent synthetic ligands of surface nucleolin and glycosaminoglycans |
EP2441520A1 (en) | 2010-10-12 | 2012-04-18 | Eppendorf AG | Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay |
WO2012049066A2 (en) | 2010-10-12 | 2012-04-19 | Eppendorf Ag | Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay |
WO2012054795A1 (en) | 2010-10-21 | 2012-04-26 | Advanced Cell Diagnostics, Inc. | An ultra sensitive method for in situ detection of nucleic acids |
CN104849472A (en) * | 2010-10-21 | 2015-08-19 | 领先细胞医疗诊断有限公司 | Ultra sensitive method for in situ detection of nucleic acids |
EP3034625A1 (en) | 2010-10-21 | 2016-06-22 | Advanced Cell Diagnostics, Inc. | An ultra sensitive method for in situ detection of nucleic acids |
WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
US9238843B2 (en) | 2010-12-27 | 2016-01-19 | Eli Lilly And Company | Compositions and methods for identifying and differentiating viral components of multivalent shipping fever vaccines |
EP3961214A1 (en) | 2010-12-31 | 2022-03-02 | BioAtla, Inc. | Comprehensive monoclonal antibody generation |
WO2012099896A2 (en) | 2011-01-17 | 2012-07-26 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
EP3216878A1 (en) | 2011-01-17 | 2017-09-13 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
EP3567121A1 (en) | 2011-01-17 | 2019-11-13 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
WO2012103414A2 (en) | 2011-01-28 | 2012-08-02 | Advanced Cell Diagnostics, Inc. | Rnascope® hpv assay for determining hpv status in head and neck cancers and cervical lesions |
WO2012109133A1 (en) | 2011-02-07 | 2012-08-16 | Research Development Foundation | Engineered immunoglobulin fc polypeptides |
US9212258B2 (en) | 2011-02-23 | 2015-12-15 | The Board Of Trustees Of The University Of Illinois | Amphiphilic dendron-coils, micelles thereof and uses |
US9770413B2 (en) | 2011-02-23 | 2017-09-26 | The Board Of Trustees Of The University Of Illinois | Amphiphilic dendron-coils, micelles thereof and uses |
WO2012120377A2 (en) | 2011-03-08 | 2012-09-13 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
US9057107B2 (en) | 2011-03-08 | 2015-06-16 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
US9914974B2 (en) | 2011-03-08 | 2018-03-13 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
WO2012125582A1 (en) | 2011-03-11 | 2012-09-20 | Board Of Regents Of The University Of Nebraska | Biomarker for coronary artery disease |
WO2012131594A1 (en) | 2011-03-28 | 2012-10-04 | Novartis Ag | Markers associated with cyclin-dependent kinase inhibitors |
EP3636279A1 (en) | 2011-04-01 | 2020-04-15 | ImmunoGen, Inc. | Methods for increasing efficacy of folr1 cancer therapy |
EP4309671A2 (en) | 2011-04-01 | 2024-01-24 | ImmunoGen, Inc. | Methods for increasing efficacy of folr1 cancer therapy |
EP3318273A1 (en) | 2011-04-01 | 2018-05-09 | ImmunoGen, Inc. | Methods for increasing efficacy of folr1 cancer therapy |
US9790262B2 (en) | 2011-04-05 | 2017-10-17 | Longevity Biotech, Inc. | Compositions comprising glucagon analogs and methods of making and using the same |
WO2012138941A1 (en) | 2011-04-05 | 2012-10-11 | Longevity Biotech, Inc. | Compositions comprising glucagon analogs and methods of making and using the same |
WO2012137147A1 (en) | 2011-04-08 | 2012-10-11 | Danisco Us, Inc. | Compositions |
US9676846B2 (en) | 2011-04-12 | 2017-06-13 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
US9150644B2 (en) | 2011-04-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
WO2012150959A1 (en) | 2011-05-04 | 2012-11-08 | Abbott Laboratories | Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor |
WO2012162179A1 (en) | 2011-05-20 | 2012-11-29 | Oligomerix, Inc. | Tau protease compositions and methods of use |
US10107826B2 (en) | 2011-05-20 | 2018-10-23 | Abbott Japan Co. Ltd. | Immunoassay methods and reagents for decreasing nonspecific binding |
US8481333B2 (en) | 2011-05-31 | 2013-07-09 | Idexx Laboratories, Inc. | Detection of degradation products of feline NT-proBNP |
EP3575792A1 (en) | 2011-05-31 | 2019-12-04 | Biogen MA Inc. | Method of assessing risk of pml |
EP4187248A1 (en) | 2011-05-31 | 2023-05-31 | Biogen MA Inc. | Method of assessing risk of pml |
WO2013010170A1 (en) | 2011-07-14 | 2013-01-17 | Lovell Mark A | Process for detection of alzheimer's disease from a serum sample |
US11013773B2 (en) | 2011-07-14 | 2021-05-25 | 4D Pharma Research Limited | Lactic acid bacterial strains |
WO2013011347A1 (en) | 2011-07-18 | 2013-01-24 | Institute For Research In Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
EP3081937A1 (en) | 2011-07-18 | 2016-10-19 | President and Fellows of Harvard College | Engineered microbe-targeting molecules and uses thereof |
EP3418300A1 (en) | 2011-07-18 | 2018-12-26 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
US10815294B2 (en) | 2011-07-18 | 2020-10-27 | Institute For Research In Biomedicine | Neutralizing anti-influenza A virus antibodies and uses thereof |
US9587010B2 (en) | 2011-07-18 | 2017-03-07 | The Institute For Research In Biomedicine | Neutralizing anti-influenza A virus antibodies and uses thereof |
EP3812397A1 (en) | 2011-07-18 | 2021-04-28 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
WO2013012924A2 (en) | 2011-07-18 | 2013-01-24 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
WO2013022599A1 (en) | 2011-08-05 | 2013-02-14 | Research Development Foundation | Improved methods and compositions for modulation of olfml3 mediated angiogenesis |
WO2013025532A2 (en) | 2011-08-12 | 2013-02-21 | Siemens Healthcare Diagnostics Inc. | Detection of sex steroids |
WO2013025834A2 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
EP3348575A1 (en) | 2011-08-16 | 2018-07-18 | Emory University | Jaml specific binding agents, antibodies, and uses related thereto |
US11266698B2 (en) | 2011-10-07 | 2022-03-08 | 4D Pharma Research Limited | Bacterium for use as a probiotic for nutritional and medical applications |
US9937211B2 (en) | 2011-10-07 | 2018-04-10 | 4D Pharma Research Limited | Composition of Roseburia hominis |
WO2013056377A1 (en) | 2011-10-21 | 2013-04-25 | Augurex Life Sciences Corporation | Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis |
CN102507917A (en) * | 2011-11-01 | 2012-06-20 | 四川金域医学检验中心有限公司 | Valproic acid homogeneous-phase enzyme immunity rapid detection kit |
WO2013101758A1 (en) | 2011-12-29 | 2013-07-04 | Baylor Research Institute | Biomarkers for kawasaki disease |
EP3418397A1 (en) | 2012-01-24 | 2018-12-26 | CD Diagnostics, Inc. | System for detecting infection in synovial fluid |
WO2013116088A1 (en) | 2012-02-02 | 2013-08-08 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detection of methodone metabolite |
EP3263564A1 (en) | 2012-02-29 | 2018-01-03 | ChemoCentryx, Inc. | Aza-aryl 1h-pyrazol-1-yl benzene sulfonamides as ccr(9) antagonists |
WO2013130811A1 (en) | 2012-02-29 | 2013-09-06 | Chemocentryx, Inc. | Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists |
EP3738958A1 (en) | 2012-02-29 | 2020-11-18 | ChemoCentryx, Inc. | Aza-aryl 1h-pyrazol-1-yl benzene sulfonamides as ccr(9) antagonists |
WO2013133917A1 (en) | 2012-03-07 | 2013-09-12 | Siemens Healthcare Diagnostics Inc. | Sandwich assay for immunosuppressant drugs |
WO2013140247A1 (en) | 2012-03-20 | 2013-09-26 | Humabs Biomed Sa | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
EP3575311A1 (en) | 2012-03-20 | 2019-12-04 | Biogen MA Inc. | Jcv neutralizing antibodies |
US10683363B2 (en) | 2012-03-30 | 2020-06-16 | The United States Of America As Represented By The Department Of Veteran Affairs | Targeting intracellular target-binding determinants with intracellular antibodies |
EP3591072A1 (en) | 2012-04-05 | 2020-01-08 | Advanced Cell Diagnostics, Inc. | Detection of immunoglobulin light chain restrication by rna in situ hybridization |
WO2013152295A1 (en) | 2012-04-05 | 2013-10-10 | Advanced Cell Diagnostics, Inc. | Detection of immunoglobulin light chain restrication by rna in situ hybridization |
EP3312296A1 (en) | 2012-04-05 | 2018-04-25 | Advanced Cell Diagnostics, Inc. | Detection of immunoglobulin light chain restrication by rna in situ hybridization |
WO2013163035A1 (en) | 2012-04-23 | 2013-10-31 | Uhl Ii, Llc | Devices and methods for detecting analyte in bodily fluid |
WO2013162751A1 (en) | 2012-04-26 | 2013-10-31 | University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
WO2013169689A1 (en) | 2012-05-07 | 2013-11-14 | Siemens Healthcare Diagnostics Inc. | Determination of total analyte concentration |
WO2013170168A1 (en) | 2012-05-10 | 2013-11-14 | Bioatla Llc | Multi-specific monoclonal antibodies |
EP3553089A1 (en) | 2012-05-10 | 2019-10-16 | Bioatla, LLC | Multi-specific monoclonal antibodies |
EP3508497A1 (en) | 2012-05-24 | 2019-07-10 | Mountgate Group Limited | Compositions and methods related to prevention and treatment of rabies infection |
US9290564B2 (en) | 2012-05-24 | 2016-03-22 | Mountgate Group Limited | Compositions and methods related to the prevention and treatment of rabies infection |
WO2013174003A1 (en) | 2012-05-24 | 2013-11-28 | Mountgate Group Limited | Compositions and methods related to prevention and treatment of rabies infection |
WO2013181530A1 (en) | 2012-06-01 | 2013-12-05 | Icahn School Of Medicine At Mount Sinai | Ceramide levels in the treatment and prevention of infections |
EP3679923A1 (en) | 2012-06-01 | 2020-07-15 | Icahn School of Medicine at Mount Sinai | Ceramide levels in the treatment and prevention of infections |
WO2013192616A1 (en) | 2012-06-22 | 2013-12-27 | Htg Molecular Diagnostics, Inc. | Molecular malignancy in melanocytic lesions |
WO2014004444A1 (en) | 2012-06-27 | 2014-01-03 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for liquid mixing assessment |
EP3309263A1 (en) | 2012-07-09 | 2018-04-18 | Novartis AG | Biomarkers associated with cdk inhibitors |
WO2014011398A1 (en) | 2012-07-09 | 2014-01-16 | Novartis Ag | Biomarkers associated with cdk inhibitors |
US9910040B2 (en) | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
WO2014014788A2 (en) | 2012-07-18 | 2014-01-23 | President And Fellows Of Harvard College | Modification of surfaces for simulataneous repellency and targeted binding of desired moieties |
EP3327090A1 (en) | 2012-07-18 | 2018-05-30 | President and Fellows of Harvard College | Modification of surfaces for simulataneous repellency and targeted binding of desired moieties |
EP3636664A1 (en) | 2012-07-27 | 2020-04-15 | The Board of Trustees of the University of Illinois | Engineering t-cell receptors |
WO2014020502A2 (en) | 2012-07-31 | 2014-02-06 | Novartis Ag | Markers associated with human double minute 2 inhibitors |
EP3494996A1 (en) | 2012-08-23 | 2019-06-12 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to 158p1d7 proteins |
US9733242B2 (en) | 2012-10-07 | 2017-08-15 | Sevident, Inc. | Devices for capturing analyte |
US9915668B2 (en) | 2012-10-12 | 2018-03-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
EP4356927A2 (en) | 2012-10-12 | 2024-04-24 | Arizona Board of Regents on behalf of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
WO2014059442A2 (en) | 2012-10-12 | 2014-04-17 | Arizona Board Agents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
US11046755B2 (en) | 2012-10-12 | 2021-06-29 | Arizona Board Of Regents On Behalf Of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
US9650436B2 (en) | 2012-10-12 | 2017-05-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Antibody based reagents that specifically recognize toxic oligomeric forms of tau |
US9395369B2 (en) | 2012-10-19 | 2016-07-19 | Regents Of The University Of Minnesota | Guinea pig cytomegalovirus (CIDMTR strain) |
WO2014063097A1 (en) | 2012-10-19 | 2014-04-24 | Danisco Us Inc. | Stabilization of biomimetic membranes |
WO2014062635A1 (en) | 2012-10-19 | 2014-04-24 | Novartis Ag | Markers for acute lymphoblastic leukemia |
WO2014066590A1 (en) | 2012-10-24 | 2014-05-01 | Research Development Foundation | Jam-c antibodies and methods for treatment of cancer |
WO2014083427A2 (en) | 2012-11-30 | 2014-06-05 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin d |
WO2014088987A1 (en) | 2012-12-04 | 2014-06-12 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of fkbp-binding immunosuppressant drugs |
EP3637105A2 (en) | 2013-01-02 | 2020-04-15 | Qiagen Sciences, LLC | Methods for predicting time-to-delivery in pregnant women |
US11353464B2 (en) | 2013-01-02 | 2022-06-07 | Qiagen Sciences, Llc | Methods for predicting time-to-delivery in pregnant women |
US9891233B2 (en) | 2013-01-02 | 2018-02-13 | N-Dia, Inc. | Methods for predicting time-to-delivery in pregnant women |
US9970929B2 (en) | 2013-01-18 | 2018-05-15 | Ark Diagnostics, Inc. | Voriconazole immunoassays |
US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
US9411930B2 (en) | 2013-02-01 | 2016-08-09 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
US10529443B2 (en) | 2013-02-01 | 2020-01-07 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
WO2014121077A2 (en) | 2013-02-01 | 2014-08-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
US11935626B2 (en) | 2013-02-01 | 2024-03-19 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
US10825553B2 (en) | 2013-02-01 | 2020-11-03 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
EP3323884A1 (en) | 2013-02-01 | 2018-05-23 | The United States Of America as Represented by the Secretary, Department of Health an Human Service | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
EP3885446A1 (en) | 2013-02-01 | 2021-09-29 | The Regents of The University of California | Methods for genome assembly and haplotype phasing |
US11081209B2 (en) | 2013-02-01 | 2021-08-03 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
US9910955B2 (en) | 2013-02-01 | 2018-03-06 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
US10089437B2 (en) | 2013-02-01 | 2018-10-02 | The Regents Of The University Of California | Methods for genome assembly and haplotype phasing |
WO2014126861A1 (en) | 2013-02-13 | 2014-08-21 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
US9920136B2 (en) | 2013-02-13 | 2018-03-20 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
US10543171B2 (en) | 2013-02-22 | 2020-01-28 | The Board Of Trustees Of The University Of Illinois | Dermal drug delivery using amphiphilic dendron-coil micelles |
WO2014141038A2 (en) | 2013-03-11 | 2014-09-18 | Irm Llc | Markers associated with wnt inhibitors |
US9273349B2 (en) | 2013-03-14 | 2016-03-01 | Affymetrix, Inc. | Detection of nucleic acids |
EP3611189A1 (en) | 2013-03-14 | 2020-02-19 | Novartis AG | Antibodies against notch 3 |
WO2014159239A2 (en) | 2013-03-14 | 2014-10-02 | Novartis Ag | Antibodies against notch 3 |
US10266879B2 (en) | 2013-03-14 | 2019-04-23 | Affymetrix, Inc. | Detection of nucleic acids |
WO2014159242A1 (en) | 2013-03-14 | 2014-10-02 | Novartis Ag | Notch 3 mutants and uses thereof |
EP3404116A1 (en) | 2013-03-15 | 2018-11-21 | The University of Chicago | Methods and compositions related to t-cell activity |
WO2014151535A1 (en) | 2013-03-15 | 2014-09-25 | Bayer Healthcare Llc | Gla domains as targeting agents |
EP4163387A1 (en) | 2013-03-15 | 2023-04-12 | The University of Chicago | Methods and compositions related to t-cell activity |
WO2014145718A2 (en) | 2013-03-15 | 2014-09-18 | Longevity Biotech, Inc. | Peptides comprising non-natural amino acids and methods of making and using the same |
WO2014151683A1 (en) | 2013-03-15 | 2014-09-25 | Bayer Healthcare Llc | Gla domains as targeting agents |
US9796762B2 (en) | 2013-04-10 | 2017-10-24 | 4D Pharma Research Limited | Polypeptide and immune modulation |
US11414463B2 (en) | 2013-04-10 | 2022-08-16 | 4D Pharma Research Limited | Polypeptide and immune modulation |
US10851137B2 (en) | 2013-04-10 | 2020-12-01 | 4D Pharma Research Limited | Polypeptide and immune modulation |
WO2014168826A1 (en) | 2013-04-12 | 2014-10-16 | Siemens Healthcare Diagnostics Inc. | Assays for analyte homologs |
WO2014176047A1 (en) | 2013-04-25 | 2014-10-30 | Novartis Ag | Markers for ezh2 inhibitors |
WO2014186402A1 (en) | 2013-05-14 | 2014-11-20 | Siemens Healthcare Diagnostics Inc. | Stabilized liquid formulations containing receptors |
EP3848045A1 (en) | 2013-05-21 | 2021-07-14 | President and Fellows of Harvard College | Engineered heme-binding compositions and uses thereof |
WO2014190040A1 (en) | 2013-05-21 | 2014-11-27 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
EP3848044A1 (en) | 2013-05-21 | 2021-07-14 | President and Fellows of Harvard College | Engineered heme-binding compositions and uses thereof |
US10677803B2 (en) | 2013-05-28 | 2020-06-09 | Biogen Ma Inc. | Method of assessing risk of PML |
US11280794B2 (en) | 2013-05-28 | 2022-03-22 | Biogen Ma Inc. | Method of assessing risk of PML |
US10119976B2 (en) | 2013-05-28 | 2018-11-06 | Biogen Ma Inc. | Method of assessing risk of PML |
WO2014200767A1 (en) | 2013-06-12 | 2014-12-18 | The General Hospital Corporation | Methods, kits, and systems for multiplexed detection of target molecules and uses thereof |
EP3587585A1 (en) | 2013-06-12 | 2020-01-01 | The General Hospital Corporation | Methods, kits, and systems for multiplexed detection of target molecules and uses thereof |
WO2014204814A1 (en) | 2013-06-18 | 2014-12-24 | Dnatrix, Inc. | Treatment of brain cancer with oncolytic adenovirus |
WO2014210540A1 (en) | 2013-06-28 | 2014-12-31 | Baylor Research Institute | Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis |
US11633500B2 (en) | 2013-08-01 | 2023-04-25 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to CD37 proteins |
US9925273B2 (en) | 2013-08-01 | 2018-03-27 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to CD37 proteins |
WO2015017552A1 (en) | 2013-08-01 | 2015-02-05 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to cd37 proteins |
US10646583B2 (en) | 2013-08-01 | 2020-05-12 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to CD37 proteins |
US11208479B2 (en) | 2013-08-21 | 2021-12-28 | Board Of Regents, The University Of Texas System | CX43 hemichannel antibodies and methods of use |
US11912762B2 (en) | 2013-08-21 | 2024-02-27 | Board Of Regents Of The University Of Texas System | Method of treating osteoarthritis by administering an anti-connexin 43 antibody |
US10633442B2 (en) | 2013-08-21 | 2020-04-28 | Board Of Regents Of The University Of Texas System | Antibodies to connexin 43 (Cx43) hemichannels and methods of use thereof to inhibit Cx43 hemichannel opening |
EP3925980A1 (en) | 2013-08-30 | 2021-12-22 | ImmunoGen, Inc. | Antibodies and assays for detection of folate receptor 1 |
US11932682B2 (en) | 2013-10-02 | 2024-03-19 | Medimmune, Llc | Neutralizing anti-influenza A antibodies and uses thereof |
US10494419B2 (en) | 2013-10-02 | 2019-12-03 | Medimmune, Llc | Neutralizing anti-influenza A antibodies and uses thereof |
US11186627B2 (en) | 2013-10-02 | 2021-11-30 | Medimmune, Llc | Neutralizing anti-influenza A antibodies and uses thereof |
US10393739B2 (en) | 2013-10-03 | 2019-08-27 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
US11585810B2 (en) | 2013-10-03 | 2023-02-21 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
US9476884B2 (en) | 2013-10-04 | 2016-10-25 | University Of Massachusetts | Hybridization- independent labeling of repetitive DNA sequence in human chromosomes |
WO2015061260A1 (en) | 2013-10-24 | 2015-04-30 | Siemens Healthcare Diagnostics Inc. | Assays for macromolecular analytes |
WO2015070009A2 (en) | 2013-11-08 | 2015-05-14 | The Board Of Regents Of The University Of Texas System | Vh4 antibodies against gray matter neuron and astrocyte |
US10172916B2 (en) | 2013-11-15 | 2019-01-08 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of treating heart failure with agonists of hypocretin receptor 2 |
WO2015077473A1 (en) | 2013-11-20 | 2015-05-28 | University Of Iowa Research Foundation | Methods and compositions for treating amyloid deposits |
WO2015077607A1 (en) | 2013-11-22 | 2015-05-28 | The Board Of Trustees Of The University Of Illinois | Engineered high-affinity human t cell receptors |
WO2015089172A1 (en) | 2013-12-13 | 2015-06-18 | Siemens Healthcare Diagnostics Inc. | Pretreatment agent in non-agglutination assays |
EP3361254A1 (en) | 2013-12-18 | 2018-08-15 | Siemens Healthcare Diagnostics Inc. | Detection of endothelial disease |
EP3546474A2 (en) | 2013-12-18 | 2019-10-02 | President and Fellows of Harvard College | Crp capture/detection of gram positive bacteria |
WO2015094527A1 (en) | 2013-12-19 | 2015-06-25 | Danisco Us Inc. | Use of hydrophobins to increase gas transferin aerobic fermentation processes |
WO2015105888A1 (en) | 2014-01-07 | 2015-07-16 | Bioatla, Llc | Proteins targeting orthologs |
US11293929B2 (en) | 2014-01-07 | 2022-04-05 | Bioatla, Inc. | Proteins targeting orthologs |
EP3447493A1 (en) | 2014-01-07 | 2019-02-27 | Bioatla, LLC | Proteins targeting orthologs |
EP3992210A1 (en) | 2014-01-13 | 2022-05-04 | Baylor Research Institute | Novel vaccines against hpv and hpv-related diseases |
WO2015116753A1 (en) | 2014-01-29 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Antibodies against the muc1-c/extracellular domain (muc1-c/ecd) |
WO2015120273A1 (en) | 2014-02-07 | 2015-08-13 | The General Hospital Corporation | Differential diagnosis of hepatic neoplasms |
WO2015123565A1 (en) | 2014-02-14 | 2015-08-20 | The General Hospital Corporation | Methods for diagnosing igg4-related disease |
WO2015131099A1 (en) | 2014-02-28 | 2015-09-03 | The General Hospital Corporation | Diagnosis of multiple myeloma and lymphoma |
EP3502698A1 (en) | 2014-05-05 | 2019-06-26 | MicroBPlex, Inc. | Media elaborated with newly synthesized antibodies and uses thereof |
EP2942627A1 (en) | 2014-05-05 | 2015-11-11 | MicroBPlex, Inc. | Media elaborated with newly synthesized antibodies (mensa) from recently proliferated antibody secreting cells (asc) and uses thereof |
US11474101B2 (en) | 2014-05-08 | 2022-10-18 | Novodiax, Inc. | Direct immunohistochemistry assay |
WO2015171938A1 (en) | 2014-05-08 | 2015-11-12 | Novodiax, Inc. | Direct immunohistochemistry assay |
WO2015179435A1 (en) | 2014-05-19 | 2015-11-26 | Bayer Healthcare Llc | Optimized humanized monoclonal antibodies against activated protein c and uses thereof |
WO2015200186A1 (en) | 2014-06-27 | 2015-12-30 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin d epimers in vitamin d assays |
WO2015200182A1 (en) | 2014-06-27 | 2015-12-30 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin d epimers |
US11174304B2 (en) | 2014-07-15 | 2021-11-16 | Medimmune, Llc | Neutralizing anti-influenza B antibodies and uses thereof |
US11787853B2 (en) | 2014-07-15 | 2023-10-17 | Medimmune, Llc | Neutralizing anti-influenza b antibodies and uses thereof |
US10294292B2 (en) | 2014-07-15 | 2019-05-21 | Medimmune, Llc | Neutralizing anti-influenza B antibodies and uses thereof |
US10519221B2 (en) | 2014-07-15 | 2019-12-31 | Medimmune, Llc | Neutralizing anti-influenza B antibodies and uses thereof |
EP4219710A2 (en) | 2014-08-01 | 2023-08-02 | Dovetail Genomics, LLC | Tagging nucleic acids for sequence assembly |
US10526641B2 (en) | 2014-08-01 | 2020-01-07 | Dovetail Genomics, Llc | Tagging nucleic acids for sequence assembly |
WO2016038550A1 (en) | 2014-09-11 | 2016-03-17 | Novartis Ag | Inhibition of prmt5 to treat mtap-deficiency-related diseases |
WO2016044234A1 (en) | 2014-09-16 | 2016-03-24 | Eric Tsao | Anti-egfr antibody and uses of same |
EP4268820A2 (en) | 2014-10-06 | 2023-11-01 | ChemoCentryx, Inc. | Combination therapy of c-c chemokine receptor-9 (ccr9) inhibitors and anti-alpha4beta7 integrin blocking antibodies for the treatment of inflammatory bowel disease |
WO2016057424A1 (en) | 2014-10-06 | 2016-04-14 | Chemocentryx, Inc. | Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies |
WO2016055950A1 (en) | 2014-10-08 | 2016-04-14 | Novartis Ag | Combination of human cytomegalovirus neutralizing antibodies |
WO2016061111A1 (en) | 2014-10-13 | 2016-04-21 | Life Technologies Corporation | Methods, kits & compositions for determining gene copy numbers |
EP3739062A1 (en) | 2014-10-20 | 2020-11-18 | Gen-Probe Incorporated | Red blood cell lysis solution |
DE102015220401A1 (en) | 2014-10-20 | 2016-05-19 | Gen-Probe Incorporated | Erythrocyte lysis solution |
WO2016064887A1 (en) | 2014-10-20 | 2016-04-28 | Gen-Probe Incorporated | Red blood cell lysis solution |
WO2016062857A1 (en) | 2014-10-24 | 2016-04-28 | Dupont Nutrition Biosciences Aps | Use of proline tolerant tripeptidyl peptidases in feed additive compositions |
WO2016062855A1 (en) | 2014-10-24 | 2016-04-28 | Dupont Nutrition Biosciences Aps | Proline tolerant tripeptidyl peptidases and uses thereof |
WO2016065238A1 (en) | 2014-10-24 | 2016-04-28 | Danisco Us Inc. | Method for producing alcohol by use of a tripeptidyl peptidase |
WO2016075546A2 (en) | 2014-11-14 | 2016-05-19 | Antonio Lanzavecchia | Antibodies that neutralize ebola virus and uses thereof |
EP3831404A1 (en) | 2014-11-18 | 2021-06-09 | Humabs Biomed S.A. | Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof |
EP3754027A1 (en) | 2014-12-01 | 2020-12-23 | The Broad Institute, Inc. | Methods for altering or modulating spatial proximity between nucleic acids inside of a cell |
WO2016089883A1 (en) | 2014-12-01 | 2016-06-09 | Novartis Ag | Compositions and methods for diagnosis and treatment of prostate cancer |
US11279974B2 (en) | 2014-12-01 | 2022-03-22 | The Broad Institute, Inc. | Method for in situ determination of nucleic acid proximity |
EP4242329A2 (en) | 2014-12-08 | 2023-09-13 | Berg LLC | Use of markers including filamin a in the diagnosis and treatment of prostate cancer |
WO2016100116A1 (en) | 2014-12-17 | 2016-06-23 | Siemens Healthcare Diagnostics Inc. | Sandwich assay design for small molecules |
US10456444B2 (en) | 2014-12-23 | 2019-10-29 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
US10973872B2 (en) | 2014-12-23 | 2021-04-13 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
US11723933B2 (en) | 2014-12-23 | 2023-08-15 | Cj Bioscience, Inc. | Composition of bacteroides thetaiotaomicron for immune modulation |
WO2016130516A1 (en) | 2015-02-09 | 2016-08-18 | Research Development Foundation | Engineered immunoglobulin fc polypeptides displaying improved complement activation |
US9715573B2 (en) | 2015-02-17 | 2017-07-25 | Dovetail Genomics, Llc | Nucleic acid sequence assembly |
US11600361B2 (en) | 2015-02-17 | 2023-03-07 | Dovetail Genomics, Llc | Nucleic acid sequence assembly |
US10318706B2 (en) | 2015-02-17 | 2019-06-11 | Dovetail Genomics, Llc | Nucleic acid sequence assembly |
WO2016138312A2 (en) | 2015-02-25 | 2016-09-01 | Vanderbilt University | Antibody-mediated neutralization of marburg virus |
US10690687B2 (en) | 2015-03-03 | 2020-06-23 | Ark Diagnostics, Inc. | Pregabalin immunoassays |
US9958464B2 (en) | 2015-03-03 | 2018-05-01 | Ark Diagnostics, Inc. | Pregabalin immunoassays |
US11703514B2 (en) | 2015-03-03 | 2023-07-18 | Ark Diagnostics, Inc. | Pregabalin immunoassays |
EP3761036A1 (en) | 2015-03-03 | 2021-01-06 | ARK Diagnostics, Inc. | Pregabalin immunoassays |
WO2016145099A1 (en) | 2015-03-09 | 2016-09-15 | Agensys, Inc. | Antibody drug conjugates (adc) that bind to flt3 proteins |
WO2016145409A1 (en) | 2015-03-11 | 2016-09-15 | The Broad Institute, Inc. | Genotype and phenotype coupling |
US11873483B2 (en) | 2015-03-11 | 2024-01-16 | The Broad Institute, Inc. | Proteomic analysis with nucleic acid identifiers |
US11807896B2 (en) | 2015-03-26 | 2023-11-07 | Dovetail Genomics, Llc | Physical linkage preservation in DNA storage |
WO2016160618A2 (en) | 2015-03-27 | 2016-10-06 | University Of Southern California | Car t-cell therapy directed to lhr for the treatment of solid tumors |
US11175584B2 (en) | 2015-03-31 | 2021-11-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for detecting traumatic brain injury |
US11180522B2 (en) | 2015-05-08 | 2021-11-23 | Centrillion Technology Holdings Corporation | Disulfide-linked reversible terminators |
EP3091026A1 (en) | 2015-05-08 | 2016-11-09 | Centrillion Technology Holdings Corporation | Disulfide-linked reversible terminators |
US10882897B2 (en) | 2015-06-01 | 2021-01-05 | Medimmune, Llc | Neutralizing anti-influenza binding molecules and uses thereof |
US11926657B2 (en) | 2015-06-01 | 2024-03-12 | Medimmune, Llc | Neutralizing anti-influenza binding molecules and uses thereof |
US10442854B2 (en) | 2015-06-01 | 2019-10-15 | Medimmune, Llc | Neutralizing anti-influenza binding molecules and uses thereof |
US11524993B2 (en) | 2015-06-01 | 2022-12-13 | Medimmune, Llc | Neutralizing anti-influenza binding molecules and uses thereof |
WO2016197064A1 (en) | 2015-06-04 | 2016-12-08 | Epstein Alan L | Lym-1 and lym-2 targeted car cell immunotherapy |
US11331352B2 (en) | 2015-06-15 | 2022-05-17 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11433106B2 (en) | 2015-06-15 | 2022-09-06 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10493112B2 (en) | 2015-06-15 | 2019-12-03 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10744167B2 (en) | 2015-06-15 | 2020-08-18 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10391130B2 (en) | 2015-06-15 | 2019-08-27 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11273185B2 (en) | 2015-06-15 | 2022-03-15 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10864236B2 (en) | 2015-06-15 | 2020-12-15 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10780134B2 (en) | 2015-06-15 | 2020-09-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11389493B2 (en) | 2015-06-15 | 2022-07-19 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10736926B2 (en) | 2015-06-15 | 2020-08-11 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10322151B2 (en) | 2015-06-15 | 2019-06-18 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10500237B2 (en) | 2015-06-15 | 2019-12-10 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11040075B2 (en) | 2015-06-15 | 2021-06-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
WO2016207402A1 (en) | 2015-06-26 | 2016-12-29 | Institute For Research In Biomedicine | Proteins comprising a mutated lair-1 fragment and uses thereof |
WO2016210395A1 (en) | 2015-06-26 | 2016-12-29 | Dupont Nutrition Biosciences Aps | Aminopeptidases for protein hydrlyzates |
WO2017011329A1 (en) | 2015-07-10 | 2017-01-19 | West Virginia University | Markers of stroke and stroke severity |
US10877045B2 (en) | 2015-07-21 | 2020-12-29 | Saint Louis University | Compositions and methods for diagnosing and treating endometriosis-related infertility |
WO2017023929A1 (en) | 2015-08-04 | 2017-02-09 | Cd Diagnostics, Inc. | Methods for detecting adverse local tissue reaction (altr) necrosis |
EP3763378A1 (en) | 2015-08-06 | 2021-01-13 | President and Fellows of Harvard College | Improved microbe-binding molecules and uses thereof |
WO2017024114A1 (en) | 2015-08-06 | 2017-02-09 | President And Fellows Of Harvard College | Improved microbe-binding molecules and uses thereof |
US11214800B2 (en) | 2015-08-18 | 2022-01-04 | The Broad Institute, Inc. | Methods and compositions for altering function and structure of chromatin loops and/or domains |
WO2017033152A1 (en) | 2015-08-25 | 2017-03-02 | Prothena Biosciences Limited | Methods for detecting phosphorylated alpha-synuclein |
WO2017040380A2 (en) | 2015-08-28 | 2017-03-09 | Research Development Foundation | Engineered antibody fc variants |
WO2017040813A2 (en) | 2015-09-02 | 2017-03-09 | University Of Massachusetts | Detection of gene loci with crispr arrayed repeats and/or polychromatic single guide ribonucleic acids |
US11390908B2 (en) | 2015-09-02 | 2022-07-19 | University Of Massachusetts | Detection of gene loci with CRISPR arrayed repeats and/or polychromatic single guide ribonucleic acids |
US11453864B2 (en) | 2015-09-08 | 2022-09-27 | University Of Massachusetts | DNase H activity of Neisseria meningitidis Cas9 |
WO2017044419A1 (en) | 2015-09-08 | 2017-03-16 | University Of Massachusetts | Dnase h activity of neisseria meningitidis cas9 |
US11001872B2 (en) | 2015-09-22 | 2021-05-11 | Shawn Clark | Designing customized protein-specific buffer system |
WO2017059108A1 (en) | 2015-09-29 | 2017-04-06 | Htg Molecular Diagnostics, Inc. | Methods for subtyping diffuse b-cell lymphoma (dlbcl) |
EP3753949A1 (en) | 2015-10-07 | 2020-12-23 | Humabs Biomed SA | Antibodies that potently neutralize hepatitis b virus and uses thereof |
US10683344B2 (en) | 2015-10-07 | 2020-06-16 | Humabs Biomed Sa | Antibodies that potently neutralize hepatitis B virus and uses thereof |
US11390664B2 (en) | 2015-10-07 | 2022-07-19 | Humabs Biomed Sa | Antibodies that potently neutralize hepatitis B virus and uses thereof |
WO2017062953A1 (en) | 2015-10-10 | 2017-04-13 | Intrexon Corporation | Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12 |
EP3913068A1 (en) | 2015-10-12 | 2021-11-24 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
US11078528B2 (en) | 2015-10-12 | 2021-08-03 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
US10457934B2 (en) | 2015-10-19 | 2019-10-29 | Dovetail Genomics, Llc | Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection |
WO2017074703A1 (en) | 2015-10-29 | 2017-05-04 | Siemens Healthcare Diagnostics Inc. | Sandwich assay for small molecules |
WO2017083296A1 (en) | 2015-11-09 | 2017-05-18 | The Children's Hospital Of Philadelphia | Glypican 2 as a cancer marker and therapeutic target |
US10471108B2 (en) | 2015-11-20 | 2019-11-12 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11058732B2 (en) | 2015-11-20 | 2021-07-13 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10610550B2 (en) | 2015-11-20 | 2020-04-07 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10744166B2 (en) | 2015-11-23 | 2020-08-18 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10391128B2 (en) | 2015-11-23 | 2019-08-27 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
EP3909983A1 (en) | 2015-12-02 | 2021-11-17 | STCube & Co. Inc. | Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof |
US11253590B2 (en) | 2015-12-02 | 2022-02-22 | Stsciences, Inc. | Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator) |
WO2017096304A1 (en) | 2015-12-04 | 2017-06-08 | Board Of Regents, The University Of Texas System | Slc45a2 peptides for immunotherapy |
WO2017109679A1 (en) | 2015-12-21 | 2017-06-29 | Novartis Ag | Compositions and methods for decreasing tau expression |
WO2017112492A2 (en) | 2015-12-22 | 2017-06-29 | The Regents Of The University Of Colorado, A Body Corporate | Protecting rnas from degradation using engineered viral rnas |
US11547756B2 (en) | 2016-01-13 | 2023-01-10 | Medimmune, Llc | Method of treating influenza A |
US10337050B2 (en) | 2016-02-11 | 2019-07-02 | Qiagen Sciences, Llc | Polyphenolic additives in sequencing by synthesis |
US10036011B2 (en) | 2016-02-11 | 2018-07-31 | Qiagen Waltham, Inc. | Scavenger compounds for improved sequencing-by-synthesis |
US11078526B2 (en) | 2016-02-11 | 2021-08-03 | IsoPlexis Corporation | Polyphenolic additives in sequencing by synthesis |
WO2017147186A1 (en) | 2016-02-22 | 2017-08-31 | Ursure, Inc. | System and method for detecting therapeutic agents to monitor adherence to a treatment regimen |
US10975417B2 (en) | 2016-02-23 | 2021-04-13 | Dovetail Genomics, Llc | Generation of phased read-sets for genome assembly and haplotype phasing |
WO2017147060A1 (en) | 2016-02-25 | 2017-08-31 | Dupont Nutrition Biosciences Aps | Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase |
US10889637B2 (en) | 2016-02-26 | 2021-01-12 | The Board Of Regents Of The University Of Texas System | Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies |
US11912758B2 (en) | 2016-02-26 | 2024-02-27 | The Board Of Regents Of The University Of Texas System | Methods of treating metastasis, including inhibiting bone cancer metastasis, by administering an antibody which binds connexin 43 (Cx43) hemichannel |
US10583158B2 (en) | 2016-03-04 | 2020-03-10 | 4D Pharma Plc | Compositions comprising bacterial strains |
US10960013B2 (en) | 2016-03-04 | 2021-03-30 | East Carolina University | J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders |
US10458995B2 (en) | 2016-03-25 | 2019-10-29 | Muralidhar Reddy Moola | Combinatorial synthesis and biomarker development |
WO2017165438A1 (en) | 2016-03-25 | 2017-09-28 | Muralidhar Reddy Moola | Combinatorial synthesis and biomarker development |
WO2017172518A1 (en) | 2016-03-29 | 2017-10-05 | Stcube, Inc. | Dual function antibodies specific to glycosylated pd-l1 and methods of use thereof |
EP3943508A1 (en) | 2016-03-29 | 2022-01-26 | Board Of Regents, The University Of Texas System | Dual function antibodies specific to glycosylated pd-l1 and methods of use thereof |
WO2017173091A1 (en) | 2016-03-30 | 2017-10-05 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein a repetitions predominant (garp) and for providing effective immunotherapy alone or in combination |
EP3736332A1 (en) | 2016-04-27 | 2020-11-11 | Gen-Probe Incorporated | Blood cell lysis reagent |
WO2017189746A1 (en) | 2016-04-27 | 2017-11-02 | Gen-Probe Incorporated | Blood cell lysis reagent |
DE202017007130U1 (en) | 2016-04-27 | 2019-08-29 | Gen-Probe Inc. | Lysis reagent for blood cells |
DE202017007129U1 (en) | 2016-04-27 | 2019-08-29 | Gen-Probe Incorporated | Lysis reagent for blood cells |
WO2017194589A1 (en) | 2016-05-10 | 2017-11-16 | Vib Vzw | Inhibition of tau-mediated early synaptic dysfunction |
US10947579B2 (en) | 2016-05-13 | 2021-03-16 | Dovetail Genomics, Llc | Recovering long-range linkage information from preserved samples |
WO2017201064A1 (en) | 2016-05-16 | 2017-11-23 | President And Fellows Of Harvard College | Aqueous biomolecule coupling on co2-plasma-activated surfaces |
WO2017214068A1 (en) | 2016-06-05 | 2017-12-14 | Berg Llc | Systems and methods for patient stratification and identification of potential biomarkers |
US10960031B2 (en) | 2016-07-13 | 2021-03-30 | 4D Pharma Plc | Compositions comprising bacterial strains |
WO2018011283A1 (en) | 2016-07-13 | 2018-01-18 | Humabs Biomed Sa | Novel antibodies specifically binding to zika virus epitopes and uses thereof |
US11224620B2 (en) | 2016-07-13 | 2022-01-18 | 4D Pharma Plc | Compositions comprising bacterial strains |
US10610549B2 (en) | 2016-07-13 | 2020-04-07 | 4D Pharma Plc | Composition comprising bacterial strains |
US11117954B2 (en) | 2016-07-13 | 2021-09-14 | Humabs Biomed Sa | Antibodies specifically binding to zika virus epitopes and uses thereof |
US10610548B2 (en) | 2016-07-13 | 2020-04-07 | 4D Pharma Plc | Compositions comprising bacterial strains |
US11912757B2 (en) | 2016-07-13 | 2024-02-27 | Humabs Biomed Sa | Antibodies specifically binding to Zika virus epitopes and uses thereof |
US10967010B2 (en) | 2016-07-13 | 2021-04-06 | 4D Pharma Plc | Compositions comprising bacterial strains |
EP4342911A1 (en) | 2016-07-13 | 2024-03-27 | Humabs Biomed SA | Novel antibodies specifically binding to zika virus epitopes and uses thereof |
WO2018017673A1 (en) | 2016-07-20 | 2018-01-25 | Stcube, Inc. | Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated pd-l1 |
WO2018015296A1 (en) | 2016-07-20 | 2018-01-25 | Vib Vzw | Therapeutic agents for neurological and psychiatric disorders |
US10919904B2 (en) | 2016-08-17 | 2021-02-16 | North Carolina State University | Northern-southern route to synthesis of bacteriochlorins |
WO2018085679A1 (en) | 2016-11-04 | 2018-05-11 | Stave James W | Direct detection of microorganisms in patient samples by immunoassay |
WO2018089231A1 (en) | 2016-11-09 | 2018-05-17 | Qiagen Sciences Llc | Photoprotective mixtures as imaging reagents in sequencing-by-synthesis |
US11162129B2 (en) | 2016-11-09 | 2021-11-02 | IsoPlexis Corporation | Photoprotective mixtures as imaging reagents in sequencing-by-synthesis |
US11324736B2 (en) | 2016-11-23 | 2022-05-10 | Chemocentryx, Inc. | Method of Treating Focal Segmental Glomerulosclerosis |
US10973809B2 (en) | 2016-11-23 | 2021-04-13 | Chemocentryx, Inc. | Method of treating focal segmental glomerulosclerosis |
WO2018100431A1 (en) | 2016-11-29 | 2018-06-07 | Genomic Vision | Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest |
US10836774B2 (en) | 2016-11-30 | 2020-11-17 | North Carolina State University | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds |
US10485830B2 (en) | 2016-12-12 | 2019-11-26 | 4D Pharma Plc | Compositions comprising bacterial strains |
US10935555B2 (en) | 2016-12-22 | 2021-03-02 | Qiagen Sciences, Llc | Determining candidate for induction of labor |
US10656164B2 (en) | 2016-12-22 | 2020-05-19 | Qiagen Sciences, Llc | Screening asymptomatic pregnant woman for preterm birth |
WO2018140606A1 (en) | 2017-01-26 | 2018-08-02 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
US11267885B2 (en) | 2017-01-26 | 2022-03-08 | Zlip Holding Limited | CD47 antigen binding unit and uses thereof |
WO2018163051A1 (en) | 2017-03-06 | 2018-09-13 | Novartis Ag | Methods of treatment of cancer with reduced ubb expression |
WO2018193063A2 (en) | 2017-04-19 | 2018-10-25 | Institute For Research In Biomedicine | Novel malaria vaccines and antibodies binding to plasmodium sporozoites |
US11382936B2 (en) | 2017-05-22 | 2022-07-12 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11123378B2 (en) | 2017-05-22 | 2021-09-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11376284B2 (en) | 2017-05-22 | 2022-07-05 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US10987387B2 (en) | 2017-05-24 | 2021-04-27 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
WO2018222685A1 (en) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1 |
WO2018222689A1 (en) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Antibodies and molecules that immunospecifically bind to btn1a1 and the therapeutic uses thereof |
US11542331B2 (en) | 2017-06-06 | 2023-01-03 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that bind to BTN1A1 or BTN1A1-ligands |
WO2018226671A1 (en) | 2017-06-06 | 2018-12-13 | Stcube & Co., Inc. | Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands |
US11660319B2 (en) | 2017-06-14 | 2023-05-30 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11779613B2 (en) | 2017-06-14 | 2023-10-10 | Cj Bioscience, Inc. | Compositions comprising a bacterial strain of the genus Megasphera and uses thereof |
US11123379B2 (en) | 2017-06-14 | 2021-09-21 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
US11007233B2 (en) | 2017-06-14 | 2021-05-18 | 4D Pharma Research Limited | Compositions comprising a bacterial strain of the genus Megasphera and uses thereof |
US10768185B2 (en) | 2017-07-20 | 2020-09-08 | Trustees Of Boston University | Tenofovir detection assay |
EP4085919A2 (en) | 2017-07-21 | 2022-11-09 | Novartis AG | Compositions and methods to treat cancer |
WO2019016772A2 (en) | 2017-07-21 | 2019-01-24 | Novartis Ag | Compositions and methods to treat cancer |
US11814431B2 (en) | 2017-08-25 | 2023-11-14 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods of use thereof |
US11306144B2 (en) | 2017-08-25 | 2022-04-19 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods of use thereof |
WO2019042555A1 (en) | 2017-08-31 | 2019-03-07 | Humabs Biomed Sa | Multispecific antibodies specifically binding to zika virus epitopes and uses thereof |
WO2019043166A1 (en) | 2017-08-31 | 2019-03-07 | Humabs Biomed Sa | Multispecific antibodies specifically binding to zika virus epitopes and uses thereof |
US11926658B2 (en) | 2017-08-31 | 2024-03-12 | Humabs Biomed Sa | Multispecific antibodies specifically binding to Zika virus epitopes |
WO2019046556A1 (en) | 2017-09-01 | 2019-03-07 | East Carolina University | Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response |
EP4265257A1 (en) | 2017-09-01 | 2023-10-25 | East Carolina University | Combination of a j-series prostaglandin-ethanolamide and a checkpoint inhibitor for use in treating cancer |
US11571401B2 (en) | 2017-09-01 | 2023-02-07 | East Carolina University | Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response |
WO2019042153A1 (en) | 2017-09-01 | 2019-03-07 | 四川科伦博泰生物医药股份有限公司 | Recombinant bispecific antibody |
WO2019050998A1 (en) | 2017-09-05 | 2019-03-14 | GLAdiator Biosciences, Inc. | Method of targeting exosomes |
WO2019050997A1 (en) | 2017-09-05 | 2019-03-14 | GLAdiator Biosciences, Inc. | Delivery of payloads to stem cells |
WO2019051002A1 (en) | 2017-09-05 | 2019-03-14 | GLAdiator Biosciences, Inc. | A method of intracellular delivery |
DE112018005145T5 (en) | 2017-09-15 | 2020-07-23 | The Regents Of The University Of California | INHIBITION OF AMINOACYLASE 3 (AA3) IN TREATMENT OF CANCER |
US11464784B2 (en) | 2017-09-15 | 2022-10-11 | The Regents Of The University Of California | Inhibition of aminocylase 3 (AA3) in the treatment of cancer |
WO2019071054A1 (en) | 2017-10-04 | 2019-04-11 | The Broad Institute, Inc. | Methods and compositions for altering function and structure of chromatin loops and/or domains |
EP4116327A1 (en) | 2017-10-11 | 2023-01-11 | Board Of Regents, The University Of Texas System | Human pd-l1 antibodies and methods of use therefor |
US11382915B2 (en) | 2017-10-11 | 2022-07-12 | Chemocentryx, Inc. | Treatment of focal segmental glomerulosclerosis with CCR2 antagonists |
US10758540B2 (en) | 2017-10-11 | 2020-09-01 | Chemocentryx, Inc. | Treatment of focal segmental glomerulosclerosis with CCR2 antagonists |
WO2019094595A2 (en) | 2017-11-09 | 2019-05-16 | Pinteon Therapeutics Inc. | Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies |
WO2019109864A1 (en) | 2017-12-04 | 2019-06-13 | 厦门万泰凯瑞生物技术有限公司 | Kit and method for quantitative detecting hbsag |
WO2019118721A2 (en) | 2017-12-15 | 2019-06-20 | Syngenta Participations Ag | Non-antibody ligands for detecting target proteins |
WO2019156758A2 (en) | 2018-01-05 | 2019-08-15 | Vanderbilt University | Antibody-mediated neutralization of chikungunya virus |
WO2019155041A1 (en) | 2018-02-12 | 2019-08-15 | Vib Vzw | Gβγ COMPLEX ANTIBODIES AND USES THEREOF |
WO2019165217A1 (en) | 2018-02-22 | 2019-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cd153 and/or cd30 in infection |
US11939383B2 (en) | 2018-03-02 | 2024-03-26 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods and use thereof |
WO2019169212A1 (en) | 2018-03-02 | 2019-09-06 | Five Prime Therapeutics, Inc. | B7-h4 antibodies and methods of use thereof |
WO2019182896A1 (en) | 2018-03-23 | 2019-09-26 | Board Of Regents, The University Of Texas System | Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor |
US11788124B2 (en) | 2018-04-09 | 2023-10-17 | Advanced Cell Diagnostics, Inc. | Methods to further enhance signal amplification for the in situ detection of nucleic acids |
WO2019199643A1 (en) | 2018-04-09 | 2019-10-17 | Bio-Techne Corporation | Methods to further enhance signal amplification for the in situ detection of nucleic acids |
EP4063519A1 (en) | 2018-04-09 | 2022-09-28 | Advanced Cell Diagnostics, Inc. | Methods to further enhance signal amplification for the in situ detection of nucleic acids |
WO2019206095A1 (en) | 2018-04-24 | 2019-10-31 | 安源医药科技(上海)有限公司 | Antibody against tim-3 and application thereof |
US11884725B2 (en) | 2018-04-24 | 2024-01-30 | Ampsource Biopharma Shanghai Inc. | Antibody against TIM-3 and application thereof |
WO2019213276A1 (en) | 2018-05-02 | 2019-11-07 | Novartis Ag | Regulators of human pluripotent stem cells and uses thereof |
WO2019244107A1 (en) | 2018-06-21 | 2019-12-26 | Daiichi Sankyo Company, Limited | Compositions including cd3 antigen binding fragments and uses thereof |
WO2020056077A1 (en) | 2018-09-13 | 2020-03-19 | The Board Of Regents Of The University Of Texas System | Novel lilrb4 antibodies and uses thereof |
WO2020069424A1 (en) | 2018-09-28 | 2020-04-02 | Centrillion Technologies, Inc. | Disulfide-linked reversible terminators |
WO2020081568A1 (en) | 2018-10-15 | 2020-04-23 | University Of Massachusetts | Programmable dna base editing by nme2cas9-deaminase fusion proteins |
WO2020081204A1 (en) | 2018-10-18 | 2020-04-23 | Oklahoma Medical Research Foundation | Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity |
WO2020082209A1 (en) | 2018-10-22 | 2020-04-30 | 上海吉倍生物技术有限公司 | Anti-cldn128.2 antibody and uses thereof |
WO2020083979A1 (en) | 2018-10-23 | 2020-04-30 | Glycardial Diagnostics, S.L. | Antibodies specific for glycosylated apoj and uses thereof |
WO2020103691A1 (en) | 2018-11-20 | 2020-05-28 | 厦门万泰凯瑞生物技术有限公司 | Specific antibody for amh, and uses thereof |
WO2020113084A1 (en) | 2018-11-28 | 2020-06-04 | Oregon Health & Science University | Therapeutic factor xii antibody |
US11315673B2 (en) | 2018-11-30 | 2022-04-26 | Caris Mpi, Inc. | Next-generation molecular profiling |
WO2020113237A1 (en) | 2018-11-30 | 2020-06-04 | Caris Mpi, Inc. | Next-generation molecular profiling |
WO2020132091A2 (en) | 2018-12-19 | 2020-06-25 | Humabs Biomed Sa | Antibodies that neutralize hepatitis b virus and uses thereof |
EP4292659A2 (en) | 2018-12-19 | 2023-12-20 | Humabs Biomed SA | Antibodies that neutralize hepatitis b virus and uses thereof |
WO2020135201A1 (en) | 2018-12-28 | 2020-07-02 | 四川科伦博泰生物医药股份有限公司 | Antibody and use thereof |
WO2020185312A2 (en) | 2019-01-25 | 2020-09-17 | President And Fellows Of Harvard College | Compositions and method for synthesizing nucleic acids |
WO2020168162A1 (en) | 2019-02-15 | 2020-08-20 | Bio-Techne Corporation | Methods for multiplex detection of nucleic acids by in situ hybridization |
US11459403B2 (en) | 2019-04-03 | 2022-10-04 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US10745492B1 (en) | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US11136412B2 (en) | 2019-04-03 | 2021-10-05 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US10919982B2 (en) | 2019-04-03 | 2021-02-16 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US11384158B2 (en) | 2019-04-03 | 2022-07-12 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US11149093B2 (en) | 2019-04-03 | 2021-10-19 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
US10717787B1 (en) | 2019-04-03 | 2020-07-21 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
WO2020211674A1 (en) | 2019-04-16 | 2020-10-22 | 四川科伦博泰生物医药股份有限公司 | Anti-fxi/fxia antibody and use thereof |
WO2020223576A1 (en) | 2019-04-30 | 2020-11-05 | Chondrial Therapeutics, Inc. | Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy |
WO2020236818A1 (en) | 2019-05-20 | 2020-11-26 | Nirvana Sciences Inc. | Narrow emission dyes, compositions comprising same, and methods for making and using same |
WO2020237491A1 (en) | 2019-05-28 | 2020-12-03 | Shanghaitech University | Composition and methods to treat ectodermal dysplasia 2, clouston type |
US11839624B2 (en) | 2019-06-26 | 2023-12-12 | Biorchestra Co., Ltd. | Micellar nanoparticles and uses thereof |
WO2020261227A1 (en) | 2019-06-26 | 2020-12-30 | Biorchestra Co., Ltd. | Micellar nanoparticles and uses thereof |
WO2021016062A1 (en) | 2019-07-19 | 2021-01-28 | The Children's Hospital Of Philadelphia | Chimeric antigen receptors containing glypican 2 binding domains |
WO2021021605A1 (en) | 2019-07-26 | 2021-02-04 | Vanderbilt University | Human monoclonal antibodies to enterovirus d68 |
WO2021030729A1 (en) | 2019-08-15 | 2021-02-18 | Psychemedics Corporation | Homogeneous enzyme immunoassay for keratinized structures |
WO2021042000A1 (en) | 2019-08-29 | 2021-03-04 | Vir Biotechnology, Inc. | Antibody compositions and methods for treating hepatitis b virus infection |
WO2021051390A1 (en) | 2019-09-20 | 2021-03-25 | 上海吉倍生物技术有限公司 | Bcma-targeted antibody and chimeric antigen receptor |
WO2021062323A1 (en) | 2019-09-26 | 2021-04-01 | Stcube & Co. | Antibodies specific to glycosylated ctla-4 and methods of use thereof |
WO2021063201A1 (en) | 2019-09-30 | 2021-04-08 | 四川科伦博泰生物医药股份有限公司 | Anti-pd-1 antibody and use thereof |
WO2021072277A1 (en) | 2019-10-09 | 2021-04-15 | Stcube & Co. | Antibodies specific to glycosylated lag3 and methods of use thereof |
US10792360B1 (en) | 2019-11-21 | 2020-10-06 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies |
US11842805B2 (en) | 2019-12-02 | 2023-12-12 | Caris Mpi, Inc. | Pan-cancer platinum response predictor |
WO2021110126A1 (en) | 2019-12-04 | 2021-06-10 | 珠海泰诺麦博生物技术有限公司 | Antibody against human cytomegalovirus and use thereof |
WO2021119402A1 (en) | 2019-12-12 | 2021-06-17 | President And Fellows Of Harvard College | Compositions and methods for light-directed biomolecular barcoding |
WO2021115240A1 (en) | 2019-12-13 | 2021-06-17 | 四川科伦博泰生物医药股份有限公司 | Anti-tslp antibody and uses thereof |
WO2021126435A1 (en) | 2019-12-20 | 2021-06-24 | Novarock Biotherapeutics, Ltd. | Anti-interleukin-23 p19 antibodies and methods of use thereof |
WO2021130390A1 (en) | 2019-12-26 | 2021-07-01 | Universitat Autònoma De Barcelona | Scaffold proteins and therapeutic nanoconjugates based on nidogen |
EP3842452A1 (en) | 2019-12-26 | 2021-06-30 | Universitat Autònoma de Barcelona | Scaffold proteins and therapeutic nanoconjugates based on nidogen |
WO2021136082A1 (en) | 2020-01-02 | 2021-07-08 | 厦门大学 | Polypeptide encoded by bnlf2b gene in eb virus and detection use thereof |
WO2021156490A2 (en) | 2020-02-06 | 2021-08-12 | Vib Vzw | Corona virus binders |
WO2021163265A1 (en) | 2020-02-11 | 2021-08-19 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov- 2) |
WO2021167908A1 (en) | 2020-02-17 | 2021-08-26 | Board Of Regents, The University Of Texas System | Methods for expansion of tumor infiltrating lymphocytes and use thereof |
WO2021170540A1 (en) | 2020-02-25 | 2021-09-02 | Vib Vzw | Leucine-rich repeat kinase 2 allosteric modulators |
WO2021173674A1 (en) | 2020-02-26 | 2021-09-02 | A2 Biotherapeutics, Inc. | Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof |
WO2021195385A1 (en) | 2020-03-26 | 2021-09-30 | Vanderbilt University | HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2) |
WO2021195418A1 (en) | 2020-03-26 | 2021-09-30 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2) |
EP4356924A2 (en) | 2020-03-26 | 2024-04-24 | Vanderbilt University | Human monoclonal antibodies to severe acute respiratory syndrome coronavirus 2 (sars-cov-2) |
US11883391B2 (en) | 2020-03-31 | 2024-01-30 | Chemocentryx, Inc. | Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-IL-23 blocking antibodies |
WO2021216728A1 (en) | 2020-04-22 | 2021-10-28 | President And Fellows Of Harvard College | Isothermal methods, compositions, kits, and systems for detecting nucleic acids |
WO2021228141A1 (en) | 2020-05-15 | 2021-11-18 | 四川科伦博泰生物医药股份有限公司 | Antibody drug conjugate, preparation method therefor and use thereof |
WO2021262840A1 (en) | 2020-06-24 | 2021-12-30 | Vir Biotechnology, Inc. | Engineered hepatitis b virus neutralizing antibodies and uses thereof |
EP3939999A1 (en) | 2020-07-14 | 2022-01-19 | Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) | Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof |
WO2022013300A1 (en) | 2020-07-14 | 2022-01-20 | Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) | Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof |
WO2022047359A1 (en) | 2020-08-31 | 2022-03-03 | Berg Llc | Protein biomarkers for pancreatic cancer |
WO2022051591A2 (en) | 2020-09-04 | 2022-03-10 | Novarock Biotherapeutics, Ltd. | Nectin-4 antibodies and uses thereof |
WO2022108897A1 (en) | 2020-11-20 | 2022-05-27 | Vanderbilt University | Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan |
WO2022120378A1 (en) | 2020-12-04 | 2022-06-09 | University Of Tennessee Research Foundation | Method for diagnosing amyloid diseases |
WO2022143743A1 (en) | 2020-12-31 | 2022-07-07 | 和铂医药(苏州)有限公司 | Human lifr antigen binding protein, preparation method therefor, and application thereof |
WO2022164805A1 (en) | 2021-01-26 | 2022-08-04 | Vir Biotechnology, Inc. | Compositions and methods for treating hepatitis b virus infection |
WO2022162192A2 (en) | 2021-01-29 | 2022-08-04 | Thelper As | Therapeutic and diagnostic agents and uses thereof |
WO2022170971A1 (en) | 2021-02-09 | 2022-08-18 | 苏州宜联生物医药有限公司 | Bioactive substance conjugate, preparation method therefor and use thereof |
WO2022175532A1 (en) | 2021-02-19 | 2022-08-25 | Vib Vzw | Cation-independent mannose-6-phosphate receptor binders |
WO2022183502A1 (en) | 2021-03-05 | 2022-09-09 | 上海吉倍生物技术有限公司 | Anti-cldn6 antibody and use thereof |
WO2022192134A1 (en) | 2021-03-08 | 2022-09-15 | Immunogen, Inc. | Methods for increasing efficacy of immunoconjugates targeting adam9 for the treatment of cancer |
WO2022188652A1 (en) | 2021-03-09 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | Ror1 binding protein and use thereof |
WO2022189558A2 (en) | 2021-03-10 | 2022-09-15 | Mabylon Ag | Antibodies against tdp-43 and methods of using the same |
WO2022216798A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for the prognosis of breast cancer progression |
WO2022216841A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer |
WO2022216846A1 (en) | 2021-04-06 | 2022-10-13 | Berg Llc | Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer |
WO2022224137A1 (en) | 2021-04-19 | 2022-10-27 | Temple Therapeutics BV | Methods for detecting or treating endometrial and ovarian hyperproliferative disorders |
WO2023288046A1 (en) | 2021-07-15 | 2023-01-19 | President And Fellows Of Harvard College | Compositions and methods relating to cells with adhered particles |
WO2023016828A2 (en) | 2021-07-30 | 2023-02-16 | Vib Vzw | Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation |
WO2023081070A1 (en) | 2021-11-02 | 2023-05-11 | University Of Massachusetts | Nme2Cas9 INLAID DOMAIN FUSION PROTEINS |
WO2023089377A2 (en) | 2021-11-19 | 2023-05-25 | Mirobio Limited | Engineered pd-1 antibodies and uses thereof |
WO2023144392A1 (en) | 2022-01-28 | 2023-08-03 | Thelper As | Therapeutic and diagnostic agents and uses thereof |
EP4238988A1 (en) | 2022-03-01 | 2023-09-06 | Consejo Superior De Investigaciones Científicas | Antibodies against sars-cov-2 and uses thereof |
WO2023187407A1 (en) | 2022-04-01 | 2023-10-05 | Bradcode Limited | Human monoclonal antibodies binding to sars-cov-2 and methods of use thereof |
WO2023192976A1 (en) | 2022-04-01 | 2023-10-05 | Board Of Regents, The University Of Texas System | Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor |
WO2023196937A1 (en) | 2022-04-06 | 2023-10-12 | Larimar Therapeutics, Inc. | Frataxin-sensitive markers for monitoring frataxin replacement therapy |
WO2023196866A1 (en) | 2022-04-06 | 2023-10-12 | Mirobio Limited | Engineered cd200r antibodies and uses thereof |
WO2023240201A1 (en) | 2022-06-08 | 2023-12-14 | Larimar Therapeutics, Inc. | Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome |
WO2023239710A1 (en) | 2022-06-08 | 2023-12-14 | Onkure, Inc. | Benzopyrimidin-4(3h)-ones as pi3k inhibitors |
WO2023239940A1 (en) | 2022-06-10 | 2023-12-14 | Research Development Foundation | Engineered fcriib selective igg1 fc variants and uses thereof |
WO2024028794A1 (en) | 2022-08-02 | 2024-02-08 | Temple Therapeutics BV | Methods for treating endometrial and ovarian hyperproliferative disorders |
WO2024040020A1 (en) | 2022-08-15 | 2024-02-22 | Absci Corporation | Quantitative affinity activity specific cell enrichment |
WO2024038160A1 (en) | 2022-08-18 | 2024-02-22 | Vib Vzw | Means and methods to modulate neuron excitability |
WO2024054469A1 (en) | 2022-09-08 | 2024-03-14 | Onkure, Inc. | Isoquinolones as pi3k inhibitors |
WO2024064024A1 (en) | 2022-09-19 | 2024-03-28 | Onkure, Inc. | ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer |
WO2024064002A1 (en) | 2022-09-20 | 2024-03-28 | Onkure, Inc. | Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation |
WO2024068744A1 (en) | 2022-09-27 | 2024-04-04 | Vib Vzw | Antivirals against human parainfluenza virus |
WO2024081345A1 (en) | 2022-10-14 | 2024-04-18 | Onkure, Inc. | Benzopyrimidin-4(3h)-ones as pi3k inhibitors |
Also Published As
Publication number | Publication date |
---|---|
BE846194Q (en) | 1976-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3817837A (en) | Enzyme amplification assay | |
US3852157A (en) | Compounds for enzyme amplification assay | |
US4067774A (en) | Compounds for enzyme amplification assay | |
US4190496A (en) | Homogeneous enzyme assay for antibodies | |
US3966556A (en) | Compounds for enzyme amplification assay methadone analogs | |
US3905871A (en) | Lactam conjugates to enzymes | |
US4181650A (en) | Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids | |
US3690834A (en) | Ligand determination with spin labeled compounds by receptor displacement | |
US3966764A (en) | Ligand determination of spin labeled compounds by receptor displacement-amphetamine analogs | |
US4404366A (en) | Beta-galactosyl-umbelliferone-labeled hapten conjugates | |
US4331590A (en) | β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates | |
US3879262A (en) | Detection and determination of haptens | |
US4469797A (en) | Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives | |
US3975237A (en) | Compounds for enzyme amplification assay - - ecgonine analogs | |
US3966744A (en) | Spin labeled compounds | |
US3935074A (en) | Antibody steric hindrance immunoassay with two antibodies | |
US4203802A (en) | Inhibitable enzyme amplification assay | |
US4130462A (en) | Receptor steric hindrance immunoassay for receptor determination | |
US4376825A (en) | Enzyme amplification compounds for assays for androgens | |
US4214048A (en) | Reagent suitable for enzyme immuno assay | |
US4282325A (en) | Enzyme bound corticosteroids | |
JPS6240662B2 (en) | ||
US4207307A (en) | Simultaneous immunoassay of multiple antigens and assay for cocaine metabolites | |
US4323647A (en) | Steric hindrance enzyme immunoassay | |
US4171244A (en) | Enzyme-bound-polyidothyronine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: DEUTSCHE BANK AG, NEW YORK Free format text: ;ASSIGNOR:DADE MICROSCAN INC.;REEL/FRAME:013516/0250 Effective date: 20021001 Owner name: DEUTSCHE BANK AG, NEW YORK Free format text: SECURITY AGREEMENT;ASSIGNOR:DADE MICROSCAN INC.;REEL/FRAME:013599/0629 Effective date: 20021003 |
|
AS | Assignment |
Owner name: DEUTSCHE BANK AG, NEW YORK Free format text: SECURITY AGREEMENT;ASSIGNOR:SYVA COMPANY;REEL/FRAME:013542/0411 Effective date: 20021001 |
|
AS | Assignment |
Owner name: DADE MICROSCAN INC., ILLINOIS Free format text: RELEASE OF SECURITY INTEREST;ASSIGNOR:DEUTSCHE BANK AG, NEW YORK BRANCH;REEL/FRAME:015953/0315 Effective date: 20050426 Owner name: SYVA COMPANY, ILLINOIS Free format text: RELEASE OF SECURITY INTEREST;ASSIGNOR:DEUTSCHE BANK AG, NEW YORK BRANCH;REEL/FRAME:015953/0326 Effective date: 20050426 |