US3833002A - Apparatus for aiding severed nerves to join - Google Patents

Apparatus for aiding severed nerves to join Download PDF

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US3833002A
US3833002A US00395906A US39590673A US3833002A US 3833002 A US3833002 A US 3833002A US 00395906 A US00395906 A US 00395906A US 39590673 A US39590673 A US 39590673A US 3833002 A US3833002 A US 3833002A
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tube
small
stem
discrete areas
faster
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J Palma
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/1128Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/30Surgical pincettes without pivotal connections
    • A61B2017/306Surgical pincettes without pivotal connections holding by means of suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30032Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in absorbability or resorbability, i.e. in absorption or resorption time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30235Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/003Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time

Definitions

  • Severed nerves in the human body sometimes grow and heal after the nerve ends are brought into alignment and close proximity, or direct contact, with each other.
  • the present invention is directed to aiding severed nerve ends to join by holding them end-to-end inside a slow-dissolving tube that, however, has small, discrete areas that dissolve relatively soon to leave small open ings which permit body fluids to contact the nerve ends inside the tube and promote the growth and healing process.
  • Another object of this invention is to provide such an apparatus which comprises a slow-dissolving tube for receiving the severed nerve ends which has small, discrete areas that dissolve much sooner than the rest of the tube so as to provide openings that enable body fluids to contact the nerve ends inside the tube.
  • FIG. I is a perspective view of a surgical tube in accordance with a first embodiment of the present invention.
  • FIG. 2 is a perspective view showing the FIG. 1 tube between two severed nerve ends that are to be joined;
  • FIG. 3 is a perspective view, partly broken away for clarity, showing the severed nerve ends inserted into the tube;
  • FIG. 4 is a longitudinal section taken along the line 4-4 in FIG. 3;
  • FIG. 5 is a view similar to FIG. 3 and showing the tube after its small, discrete, fast-dissolving areas have dissolved in the body, but before the slow-dissolving principal part of the tube has dissolved;
  • FIG. 6 is a perspective view of a second, T-shaped embodiment of the present surgical tube having a transverse stem for applying vacuum to the interior of the tube where the severed nerve ends are received;
  • FIG. 7 is a longitudinal section taken along the line 7-7 in FIG. 6;
  • FIG. 8 is a perspective view of a Y-shaped surgical tube receiving the severed nerve ends, with a transverse stem as one leg of the Y, in accordance with a third embodiment of this invention.
  • FIG. 9 is a longitudinal section through the FIG. 8 surgical tube
  • FIG. 10 is a perspective view of a different form of generally Y-shaped surgical tube in accordance with a fourth embodiment of this invention.
  • FIG. 11 is a longitudinal section through the FIG. 10 tube
  • FIG. 12 is a perspective view of a fifth embodiment of the present surgical tube, having aligned, transverse inlet and outlet stems;
  • FIG. 13 is an enlarged longitudinal section through a wall of a surgical tube which has small, discrete areas which dissolve relatively rapidly because they are thin, in accordance with another embodiment of this invention.
  • the surgical tube shown there is a cylindrical tube having open opposite ends 21 and 22 into which the severed nerve ends 23 and 24 can be inserted slidably.
  • the inside diameter of the tube is slightly greater than the diameter of the nerve ends to permit such slidable insertion to be performed quickly and easily.
  • the opposite ends of the tube preferably are sealed with medical sealing material, as shown at 25 and 26 in FIG. 3 and 4.
  • the tube 20 has a wall thickness and a composition, such as animal tissue, such that it is dissolved, absorbed or digested in the human body relatively slowly. For example, it may take six months for the complete wall thickness of the tube to be completely dissolved.
  • the tube 20 is provided with small, localized, discrete areas that are dissolved, absorbed or digested by the body much more rapidly than the principal part of the tube.
  • these localized areas may dissolve completely in about 24 hours.
  • these small, discrete areas are provided by discrete particles 27 of a relatively fast-dissolving material, such as sugar which are embedded in the tube wall and occupy the full thickness of the tube wall at these small areas. After a relatively short time in the body, these particles dissolve completely, leaving small discrete openings 27a in the surgical tube, as shown in FIG. 5. These small, discrete openings permit the passage of body fluids into contact with the nerve ends inside the tube to enhance the healing action as the severed nerve ends gradually join together. After this healing process is fully completed, or substantially so, the principal material of the surgical tube 20 also dissolves completely in the body.
  • a relatively fast-dissolving material such as sugar which are embedded in the tube wall and occupy the full thickness of the tube wall at these small areas.
  • the fast-dissolving, small, discrete areas of the surgical tube may be provided by thin-walled web portions of the tube.
  • the tube wall 30 may have indentations or recesses 31 and 32 in its outside and inside faces, leaving only a thin web 33 between them that will dissolve much more rapidly than the full-thickness remainder of the tube.
  • a recess or identation 34 may be formed in only one face of the tube, leaving only a fast-dissolving thin web 35 behind it. It is to be understood that these thin web, fast-dissolving portions of the tube are made of the same material as the slowdissolving much thicker remainder of the tube; they dissolve faster simply because they are thinner.
  • the present surgical tube may be T-shaped, with a transverse, serrated stem 40 midway between its opposite ends.
  • This stem has a central passage 41 communicating with the interior of the tube where the nerve ends are received.
  • the stem may be attached to a hose, indicated in phantom at 42 in FIG. 7, to enable vacuum to be applied to the interior of the tube while the nerve ends 23 and 24 are being inserted, so as to draw them into direct contact or close proximity with each other.
  • the nerve-receiving opposite ends 21 and 22 of the tube are sealed by medical sealing material and 26, and after removal of the vacuum hose 42 at the end of the stem may be closed by such sealing material, also.
  • the stem 40 is of the same construction as the tube proper, being composed primarily of a slow-dissolving material and having small, discrete particles 27 of the fast-dissolving material.
  • FIGS. 8 and 9 show another embodiment of this surgical tube in which the severed nerve ends are received in straight legs 20a and 20b of the tube which are inclined at an obtuse angle to each other.
  • the transverse, serrated stem 40 is joined to these legs 20a and 20b at the intersection between them so as to provide with them a Y-shaped surgical tube.
  • Both legs 20a and 20b and the stem 40 have small, discrete particles 27 of the fastdissolving material embedded in them.
  • FIGS. 10 and 11 show another embodiment which is generally similar to that of FIGS. 8 and 9, except that it has opposite, nerve end-receiving legs 20c and 20d which curve toward each other and merge together smoothly where the stem 40 is connected to them. Both legs 20c and 20d and the stem 40 have small, discrete particles 27 of the fast-dissolving material embedded in them.
  • FIG. 12 shows yet another embodiment whose configuration is as disclosed and claimed in my copending US. pat. application, Ser. No. 258,737, filed June 1, I972, now US. Pat. No. 3,786,8l7.
  • straight tube 20 is provided with two longitudinally spaced, transverse stems and 51 having central passages 52 and 53, respectively. which communicate with the nerve ends that are inserted into the opposite ends 21 and 22 of the tube.
  • One of these stems serves as an inlet and the other as an outlet for filling the interior of the tube with a suitable healing ambience or substance that enhances the healing and joining together of the nerve ends during the period immediately following the insertion of the nerve ends into the tube.
  • Both stems 50 and 51 and the remainder of the tube 20 contain small discrete particles of the fast-dissolving material.
  • the tube ends 21 and 22 are sealed with medical sealing material after the severed nerve ends have been inserted and before the healing ambience is added. After the healing ambience has been added, the open ends of the stems 50 and 51 may be squeezed closed or closed by medical sealing material.
  • all or part of the surgical tube may have the small, discrete faster-dissolving areas provided by thin web portions of the tube wall or stem wall, in place of the particles 27 of a faster-dissolving material different from the material of which the tube is primarily composed.
  • the slow-dissolving main body of the tube may consist of layers which dissolve successively.
  • Apparatus for aiding severed nerves to join comprising a tube having open opposite ends into which the nerve ends can be inserted, said tube being composed principally of a material that dissolves slowly in the body and having small discrete areas therein which dissolve in the body substantially faster than the remainder of the tube to provide small openings for the passage of body fluids into contact with the nerve ends inside the tube, said small, discrete areas being provided by embedded bodies of a different material than the principal material of the tube which dissolves in the body faster than the principal material of the tube.
  • a surgical tube for aiding severed nerves to join together said tube being dimensioned to receive the nerve ends in its opposite ends and throughout most of its extent having a wall thickness and a composition effective to prevent the tube from completely dissolving in the body for several days, the improvement which comprises:
  • said last mentioned means comprising small, discrete web portions of the tube wall which are substantially thinner radially than the remainder of the tube wall.

Abstract

A surgical tube for aiding severed nerves to join, composed primarily of a slow-dissolving material and having small, discrete areas which dissolve faster. These discrete areas may be provided by particles of a different, faster-dissolving material that are embedded in the tube wall, or by a greatly reduced thickness of the tube wall itself at these areas.

Description

United States Patent Palma 1 1 Sept. 3, 1974 [54] APPARATUS FOR AIDING SEVERED 3,683,926 8/1972 Suzuki 128/334 R N V o O 3,786,817 l/l974 Palma 128/334 R [76] Inventor: James R. Palma, 1502 Curry Rd., FO EIGN TE TS OR APPLICATIONS Schenec dy, NY. 12306 591,509 8/1947 Great Britain 128/334 R l [22] Filed: Sept. 10, 1973 Primary Examiner-Lucie H. Laudenslager [21] APPI' 395,906 Attorney, Agent, or Firm-Oltman and Flynn [52] US. Cl. 128/334 R, 128/346 57 ABSTRACT [51] Int. Cl A61b 17/04 [58] Field of Search 128/334 C 334 R 346 A surg1cal tube for aiding severed nerves to 10m, com- 128 /3 49 DIG posed primarily of a slow-dissolving material and having small, discrete areas which dissolve faster. These [56] References Cited discrete areas may be provided by particles of a different, faster-dissolving material that are embedded in UNITED STATES PATENTS the tube wall, or by a greatly reduced thickness of the IBdOWGII g tube wall itself at these areas yng 3,587,586 6/1971 Kronenthal 4. 128/334 R 7 Claims, 13 Drawing Figures PATENIH'JSEP 31am SHEET 1 0F 2 FIG.7
3,ess;002
PATENTEI] SEP 3 I974 mraura FIG. 13
APPARATUS FOR AIDING SEVERED NERVES TO JOIN BACKGROUND OF THE INVENTION Severed nerves in the human body sometimes grow and heal after the nerve ends are brought into alignment and close proximity, or direct contact, with each other.
In US. Pat. No. 2,127,903 to Bowen, it has been proposed to heal a severed nerve by suturing the nerve ends and anchoring a sheath of absorbable animal membrane around them.
SUMMARY OF THE INVENTION The present invention is directed to aiding severed nerve ends to join by holding them end-to-end inside a slow-dissolving tube that, however, has small, discrete areas that dissolve relatively soon to leave small open ings which permit body fluids to contact the nerve ends inside the tube and promote the growth and healing process.
Accordingly, it is a principal object of this invention to provide a novel and improved apparatus for aiding severed nerve ends to join.
Another object of this invention is to provide such an apparatus which comprises a slow-dissolving tube for receiving the severed nerve ends which has small, discrete areas that dissolve much sooner than the rest of the tube so as to provide openings that enable body fluids to contact the nerve ends inside the tube.
Further objects and advantages of this invention will be apparent from the following detailed description of several presently-preferred embodiments, shown in the accompanying drawings in which:
FIG. I is a perspective view of a surgical tube in accordance with a first embodiment of the present invention;
FIG. 2 is a perspective view showing the FIG. 1 tube between two severed nerve ends that are to be joined;
FIG. 3 is a perspective view, partly broken away for clarity, showing the severed nerve ends inserted into the tube;
FIG. 4 is a longitudinal section taken along the line 4-4 in FIG. 3;
FIG. 5 is a view similar to FIG. 3 and showing the tube after its small, discrete, fast-dissolving areas have dissolved in the body, but before the slow-dissolving principal part of the tube has dissolved;
FIG. 6 is a perspective view of a second, T-shaped embodiment of the present surgical tube having a transverse stem for applying vacuum to the interior of the tube where the severed nerve ends are received;
FIG. 7 is a longitudinal section taken along the line 7-7 in FIG. 6;
FIG. 8 is a perspective view of a Y-shaped surgical tube receiving the severed nerve ends, with a transverse stem as one leg of the Y, in accordance with a third embodiment of this invention;
FIG. 9 is a longitudinal section through the FIG. 8 surgical tube;
FIG. 10 is a perspective view of a different form of generally Y-shaped surgical tube in accordance with a fourth embodiment of this invention;
FIG. 11 is a longitudinal section through the FIG. 10 tube;
FIG. 12 is a perspective view of a fifth embodiment of the present surgical tube, having aligned, transverse inlet and outlet stems; and
FIG. 13 is an enlarged longitudinal section through a wall of a surgical tube which has small, discrete areas which dissolve relatively rapidly because they are thin, in accordance with another embodiment of this invention.
Before explaining in detail the disclosed embodiments of the present invention, it is to be understood that the invention is not limited in its application to the details of the particular arrangements shown since the invention is capable of other embodiments. Also, the terminology used herein is for the purpose of description and not of limitation. I
DETAILED DESCRIPTION Referring first to FIGS. 1-4, the surgical tube shown there is a cylindrical tube having open opposite ends 21 and 22 into which the severed nerve ends 23 and 24 can be inserted slidably. The inside diameter of the tube is slightly greater than the diameter of the nerve ends to permit such slidable insertion to be performed quickly and easily. After the nerve ends are inserted into the tube, the opposite ends of the tube preferably are sealed with medical sealing material, as shown at 25 and 26 in FIG. 3 and 4.
For most of its extent the tube 20 has a wall thickness and a composition, such as animal tissue, such that it is dissolved, absorbed or digested in the human body relatively slowly. For example, it may take six months for the complete wall thickness of the tube to be completely dissolved.
In accordance with the present invention, the tube 20 is provided with small, localized, discrete areas that are dissolved, absorbed or digested by the body much more rapidly than the principal part of the tube. For example, these localized areas may dissolve completely in about 24 hours.
In the embodiment of FIGS. 15, these small, discrete areas are provided by discrete particles 27 of a relatively fast-dissolving material, such as sugar which are embedded in the tube wall and occupy the full thickness of the tube wall at these small areas. After a relatively short time in the body, these particles dissolve completely, leaving small discrete openings 27a in the surgical tube, as shown in FIG. 5. These small, discrete openings permit the passage of body fluids into contact with the nerve ends inside the tube to enhance the healing action as the severed nerve ends gradually join together. After this healing process is fully completed, or substantially so, the principal material of the surgical tube 20 also dissolves completely in the body.
As shown in FIG. 13, the fast-dissolving, small, discrete areas of the surgical tube may be provided by thin-walled web portions of the tube. For example, the tube wall 30 may have indentations or recesses 31 and 32 in its outside and inside faces, leaving only a thin web 33 between them that will dissolve much more rapidly than the full-thickness remainder of the tube. Alternatively or additionally, a recess or identation 34 may be formed in only one face of the tube, leaving only a fast-dissolving thin web 35 behind it. It is to be understood that these thin web, fast-dissolving portions of the tube are made of the same material as the slowdissolving much thicker remainder of the tube; they dissolve faster simply because they are thinner.
As shown in FIGS. 6 and 7, the present surgical tube may be T-shaped, with a transverse, serrated stem 40 midway between its opposite ends. This stem has a central passage 41 communicating with the interior of the tube where the nerve ends are received. The stem may be attached to a hose, indicated in phantom at 42 in FIG. 7, to enable vacuum to be applied to the interior of the tube while the nerve ends 23 and 24 are being inserted, so as to draw them into direct contact or close proximity with each other. After this has been done, the nerve-receiving opposite ends 21 and 22 of the tube are sealed by medical sealing material and 26, and after removal of the vacuum hose 42 at the end of the stem may be closed by such sealing material, also.
The stem 40 is of the same construction as the tube proper, being composed primarily of a slow-dissolving material and having small, discrete particles 27 of the fast-dissolving material.
FIGS. 8 and 9 show another embodiment of this surgical tube in which the severed nerve ends are received in straight legs 20a and 20b of the tube which are inclined at an obtuse angle to each other. The transverse, serrated stem 40 is joined to these legs 20a and 20b at the intersection between them so as to provide with them a Y-shaped surgical tube. Both legs 20a and 20b and the stem 40 have small, discrete particles 27 of the fastdissolving material embedded in them.
FIGS. 10 and 11 show another embodiment which is generally similar to that of FIGS. 8 and 9, except that it has opposite, nerve end-receiving legs 20c and 20d which curve toward each other and merge together smoothly where the stem 40 is connected to them. Both legs 20c and 20d and the stem 40 have small, discrete particles 27 of the fast-dissolving material embedded in them.
FIG. 12 shows yet another embodiment whose configuration is as disclosed and claimed in my copending US. pat. application, Ser. No. 258,737, filed June 1, I972, now US. Pat. No. 3,786,8l7. In this embodiment straight tube 20 is provided with two longitudinally spaced, transverse stems and 51 having central passages 52 and 53, respectively. which communicate with the nerve ends that are inserted into the opposite ends 21 and 22 of the tube. One of these stems serves as an inlet and the other as an outlet for filling the interior of the tube with a suitable healing ambience or substance that enhances the healing and joining together of the nerve ends during the period immediately following the insertion of the nerve ends into the tube. Both stems 50 and 51 and the remainder of the tube 20 contain small discrete particles of the fast-dissolving material. The tube ends 21 and 22 are sealed with medical sealing material after the severed nerve ends have been inserted and before the healing ambience is added. After the healing ambience has been added, the open ends of the stems 50 and 51 may be squeezed closed or closed by medical sealing material.
It is to be understood that in each of the embodiments of FIGS. 6I2, as well as in the embodiment of FIGS. 1-5, all or part of the surgical tube may have the small, discrete faster-dissolving areas provided by thin web portions of the tube wall or stem wall, in place of the particles 27 of a faster-dissolving material different from the material of which the tube is primarily composed. The slow-dissolving main body of the tube may consist of layers which dissolve successively.
I claim:
1. Apparatus for aiding severed nerves to join comprising a tube having open opposite ends into which the nerve ends can be inserted, said tube being composed principally of a material that dissolves slowly in the body and having small discrete areas therein which dissolve in the body substantially faster than the remainder of the tube to provide small openings for the passage of body fluids into contact with the nerve ends inside the tube, said small, discrete areas being provided by embedded bodies of a different material than the principal material of the tube which dissolves in the body faster than the principal material of the tube.
, 2. Apparatus according to claim 1, wherein said tube has a transverse stem leading into its interior between its ends, said stem having small, discrete areas therein which dissolve in the body substantially faster than the remainder of the tube.
3. Apparatus according to claim 2, wherein said small, discrete areas in said stem are provided by em bedded bodies of a different material which dissolves in the body faster than the principal material of the tube.
4. Apparatus according to claim 2, wherein said tube and stem together are substantially T-shaped.
5. Apparatus according to claim 2, wherein said tube and stem together are substantially Y-shaped.
6. Apparatus according to claim 1, wherein said tube has a transverse inlet stem and a transverse outlet stem spaced from said inlet stern along the length of the tube and both communicating with the interior of the tube, said stems both having small discrete areas therein which dissolve in the body substantially faster than the remainder of the tube.
7. In a surgical tube for aiding severed nerves to join together, said tube being dimensioned to receive the nerve ends in its opposite ends and throughout most of its extent having a wall thickness and a composition effective to prevent the tube from completely dissolving in the body for several days, the improvement which comprises:
means providing small, discrete areas in the tube wall which dissolve in the body substantially faster than the remainder of the tube to leave small openings permitting body fluids to pass into contact with the nerve ends inside the tube,
said last mentioned means comprising small, discrete web portions of the tube wall which are substantially thinner radially than the remainder of the tube wall.

Claims (7)

1. Apparatus for aiding severed nerves to join comprising a tube having open opposite ends into which the nerve ends can be inserted, said tube being composed principally of a material that dissolves slowly in the body and having small discrete areas therein which dissolve in the body substantially faster than the remainder of the tube to provide small openings for the passage of body fluids into contact with the nerve ends inside the tube, said small, discrete areas being provided by embedded bodies of a different material than the principal material of the tube which dissolves in the body faster than the principal material of the tube.
2. Apparatus according to claim 1, wherein said tube has a transverse stem leading into its interior between its ends, said stem having small, discrete areas therein which dissolve in the body substantially faster than the remainder of the tube.
3. Apparatus according to claim 2, wherein said small, discrete areas in said stem are provided by embedded bodies of a different material which dissolves in the body faster than the principal material of the tube.
4. Apparatus according to claim 2, wherein said tube and stem together are substantially T-shaped.
5. Apparatus according to claim 2, wherein said tubE and stem together are substantially Y-shaped.
6. Apparatus according to claim 1, wherein said tube has a transverse inlet stem and a transverse outlet stem spaced from said inlet stem along the length of the tube and both communicating with the interior of the tube, said stems both having small discrete areas therein which dissolve in the body substantially faster than the remainder of the tube.
7. In a surgical tube for aiding severed nerves to join together, said tube being dimensioned to receive the nerve ends in its opposite ends and throughout most of its extent having a wall thickness and a composition effective to prevent the tube from completely dissolving in the body for several days, the improvement which comprises: means providing small, discrete areas in the tube wall which dissolve in the body substantially faster than the remainder of the tube to leave small openings permitting body fluids to pass into contact with the nerve ends inside the tube, said last mentioned means comprising small, discrete web portions of the tube wall which are substantially thinner radially than the remainder of the tube wall.
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Cited By (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916905A (en) * 1973-11-09 1975-11-04 William E Kuhn Method and means for the repair of severed peripheral nerves
US4013078A (en) * 1974-11-25 1977-03-22 Feild James Rodney Intervertebral protector means
US4306561A (en) * 1979-11-05 1981-12-22 Ocean Trading Co., Ltd. Holding apparatus for repairing severed nerves and method of using the same
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US3916905A (en) * 1973-11-09 1975-11-04 William E Kuhn Method and means for the repair of severed peripheral nerves
US4013078A (en) * 1974-11-25 1977-03-22 Feild James Rodney Intervertebral protector means
US4306561A (en) * 1979-11-05 1981-12-22 Ocean Trading Co., Ltd. Holding apparatus for repairing severed nerves and method of using the same
US4350160A (en) * 1979-11-14 1982-09-21 Kolesov Evgeny V Instrument for establishing vascular anastomoses
US4501029A (en) * 1982-04-22 1985-02-26 Mcminn Derek J W Tendon repair
WO1984003035A1 (en) * 1983-02-02 1984-08-16 Minnesota Mining & Mfg Absorbable nerve repair device and method
US4623355A (en) * 1984-03-16 1986-11-18 Sawruk Stephen D Prosthetic axon
US4778467A (en) * 1984-04-25 1988-10-18 The University Of Utah Prostheses and methods for promoting nerve regeneration and for inhibiting the formation of neuromas
US4662884A (en) * 1984-04-25 1987-05-05 University Of Utah Research Foundation Prostheses and methods for promoting nerve regeneration
JPS62144663A (en) * 1985-12-17 1987-06-27 アライド・コ−ポレ−シヨン Transplanting accessory comprising living body re-absorbable polymer
EP0226061A3 (en) * 1985-12-17 1988-07-20 Allied Corporation High molecular weight bioresorbable polymers and implantation devices thereof
EP0226061A2 (en) * 1985-12-17 1987-06-24 United States Surgical Corporation High molecular weight bioresorbable polymers and implantation devices thereof
JPH0552749B2 (en) * 1985-12-17 1993-08-06 Allied Signal Inc
EP0261833A3 (en) * 1986-09-09 1990-07-18 American Biointerface Corporation Apparatus for mammalian nerve regeneration
EP0261833A2 (en) * 1986-09-09 1988-03-30 American BioInterface Corporation Apparatus for mammalian nerve regeneration
US5019087A (en) * 1986-10-06 1991-05-28 American Biomaterials Corporation Nerve regeneration conduit
WO1988004557A1 (en) * 1986-12-17 1988-06-30 Allied Corporation Implantable devices having hydrophobic component
WO1988006866A1 (en) * 1987-03-13 1988-09-22 Brown University Research Foundation, Inc. Piezolectric nerve guidance channels
AU606410B2 (en) * 1987-03-13 1991-02-07 Brown University Research Foundation Piezoelectric nerve guidance channels
US5030225A (en) * 1987-03-13 1991-07-09 Brown University Research Foundation Electrically-charged nerve guidance channels
US4877029A (en) * 1987-03-30 1989-10-31 Brown University Research Foundation Semipermeable nerve guidance channels
US4878913A (en) * 1987-09-04 1989-11-07 Pfizer Hospital Products Group, Inc. Devices for neural signal transmission
JPH02502416A (en) * 1987-11-20 1990-08-02 ハイデルベルク モトール ゲゼルシャフト ミット ベシュレンクテル ハフツング ゲゼルシャフト フュール エネルギーコンヴェルテル high current switch
WO1989010728A1 (en) * 1988-05-09 1989-11-16 Massachusetts Institute Of Technology Prosthesis for promotion of nerve regeneration
US5011486A (en) * 1988-11-18 1991-04-30 Brown University Research Foundation Composite nerve guidance channels
EP0370917A2 (en) * 1988-11-23 1990-05-30 Claude Proulx Splint-like element for use in end-to-end nerve suture
EP0370917A3 (en) * 1988-11-23 1991-07-17 Claude Proulx Splint-like element for use in end-to-end nerve suture
US5350388A (en) * 1989-03-07 1994-09-27 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US5026381A (en) * 1989-04-20 1991-06-25 Colla-Tec, Incorporated Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit
US5354305A (en) * 1991-09-26 1994-10-11 United States Surgical Corporation Nerve repair device
FR2685628A1 (en) * 1991-12-30 1993-07-02 Berque Jean OPTICAL FIBER (S) DEVICE FOR THE REPAIR OF LESED NERVOUS FIBERS.
WO1993012724A1 (en) * 1991-12-30 1993-07-08 Jean Berque Optical fibre device intended to the repair of damaged nerve fibres
US6106556A (en) * 1994-12-02 2000-08-22 Omeros Medical Systems, Inc. Tendon and ligament repair system
US5800544A (en) * 1994-12-02 1998-09-01 Omeros Medical Systems, Inc. Tendon and ligament repair system
US6080192A (en) * 1994-12-02 2000-06-27 Omeros Medical Systems, Inc. Tendon and ligament repair system
WO1997006752A1 (en) * 1995-08-16 1997-02-27 Frank Lampe Endoprosthesis, in particular an artificial hip joint
US6071312A (en) * 1995-08-16 2000-06-06 Lampe; Frank Endoprosthesis, in particular an artificial hip joint
WO1997011724A1 (en) * 1995-09-27 1997-04-03 Biocon Oy Biodegradable implant manufactured of polymer-based material and a method for manufacturing the same
US6228111B1 (en) 1995-09-27 2001-05-08 Bionx Implants Oy Biodegradable implant manufactured of polymer-based material and a method for manufacturing the same
US6808530B2 (en) * 1996-07-26 2004-10-26 Karolinska Innovations Ab Medical device for treatment of a gap or defect in the central nerve system
US20040215218A1 (en) * 1999-12-23 2004-10-28 Omeros Corporation Tendon repair using internal reinforcing member
US6740100B2 (en) 1999-12-23 2004-05-25 Omeros Corporation Tendon repair using adhesive
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US20040111140A1 (en) * 2001-01-11 2004-06-10 Thomas Stieglitz Sieve electrode which can be connected to a nerve stump
US6908470B2 (en) * 2001-01-11 2005-06-21 Fraunhofer-Gesellschaft Zur Foderung Der Angewandten Forschung E.V. Sieve electrode which can be connected to a nerve stump
DE10205997A1 (en) * 2002-02-14 2003-09-04 Hm Medical Engineering Gmbh Joint element, in particular suitable for connecting vessel or nerve sections, enveloped by barbed sleeve
FR2836817A1 (en) * 2002-03-11 2003-09-12 Ind Tech Res Inst A bioresorbable conduit with multiple channels for medical use in the regeneration of damaged or severed nerves has a hollow porous tube within which is a folded or spiral film of bioresorbable filling material with an irregular surface
US7147647B2 (en) 2002-04-26 2006-12-12 Medtronic, Inc. Sintered titanium tube for the management of spinal cord injury
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US20080300691A1 (en) * 2003-11-05 2008-12-04 Texas Scottish Rite Hospital For Children Biomimetic Synthetic Nerve Implant Casting Device
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