US3844286A - Releasable medicament dental carrier and method - Google Patents
Releasable medicament dental carrier and method Download PDFInfo
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- US3844286A US3844286A US00387553A US38755373A US3844286A US 3844286 A US3844286 A US 3844286A US 00387553 A US00387553 A US 00387553A US 38755373 A US38755373 A US 38755373A US 3844286 A US3844286 A US 3844286A
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- medicament
- fluoride
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
- A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
Definitions
- MEDICAMENT FIG "2 MEDICAMENT I” This invention relates to a foam carrier having a releasable medicament contained within channel portions thereof for use in dental treatment. More particularly the present invention provides a foam carrier which releases limited amounts of a medicament such as a fluoride, directly to the teeth in the oral cavity during dental treatment.
- a medicament such as a fluoride
- a variety of dental treatment devices are known in the art for treatment of diseases such as dental caries, pyorrhea, gingivitis and trench mouth. Proper treatment of these diseases requires that a medicament be in solution and in direct contact with the teeth and gums.
- prior art devices provide means for jacketing treating solutions thus requiring separate application of solution and device.
- controlled amounts of solution must be employed which is difficult in actual practice with the likelihood of spillage being significant.
- Liquid acid phosphate-fluoride solutions have been clinically employed by dentists for topical application to teeth for the purpose of preventing or reducing dental caries. Clinical studies have shown the cariesreducing effectiveness of a single application of liquid acid phosphate-fluoride preparations. in practice these solutions have been applied by the dentist who makes a wax impression of the patients teeth which is used as a mold in which the liquid acid phosphate-fluoride preparation is placed before applying the impression bring the preparation into intimate contact with the teeth. However, this practice has been found unsatisfactory in that the available liquid preparations tend to run out from the wax impression, particularly where the teeth in the lower jaw are being treated.
- a new improved dental device having a pre-disposed medicament in non-liquid state dispersed such that active portions thereof may be controllably released for dental treatment by the fluids of the oral cavity adjacent to the surfaces of the teeth, and by a slight bite pressure into the foam carrier.
- FIG. 1 illustrates in perspective the present flexible foam l-beam shape carrier as it normally appears
- FIG. 2 is a side elevational view of the present carrier into which is channeled a medicament disposed for subsequent release;
- FIG. 3 illustrates the present device in the configuration prior to introduction into the mouth of a patient
- FIG. 4 illustrates in partial section, the present device in contact with teeth and gum tissue during treatment.
- FIGS. 1 and 2 illustrate foam carrier 10 having side walls 12 and 14 joined by intermediate ridge portion 16.
- a medicament is disposed onto the foam carrier within channel portions defined by walls 20, by most any convenient means.
- the medicament may be disposed onto the channel portions of the carrier by a number of different means.
- finely divided particles of medicament may be incorporated in a soluble adhesive.
- a solution of medicament may be prepared and dried on the foam carrier.
- the present carrier may be made of open cell or closed cell foam cushioning material.
- open cell or closed cell foam cushioning material includes for example, latex, polystyrene, polyurethane or related open cell foams.
- Polyurethane foam has been 5 found to be a good open cell material for use in making the carrier and is preferred.
- the fluoride compound component must be substantially soluble in water and ionize by fluids adjacent the teeth to provide a source of fluoride ions.
- Fluoride 0 compounds which have been found satisfactory include sodium fluoride, potassium fluoride, ammonium fluoride, sodium bifluoride, potassium bifluoride, ammonium bifluoride and sodium silicofluoride.
- Other fluoride compounds including combined chemical com- 5 pounds which yield fluoride ions in dilute aqueous solu-
- the present dental carrier has a flex- 6O ible foam l-beam configuration with medicament disposed on channel portions thereof.
- the device is conveniently prepared in a continuous strip which, because of the flexibility of the foam, may be readily severed to tions may be also utilized.
- the device of this invention contains a sufficient amount of such a fluoride compound to provide about 0.25 to about 5.0 percent of fluoride ions and preferably about 1.25 percent in contact with the teeth.
- acid phosphate When acid phosphate is used, it must also be substantially water-soluble and provide the desired phosphate ions.
- acid phosphate compounds which may be used include orthophosphoric acid, monosodium phosphate, monopotassium phosphate, disodium phosphate, dipotassium phosphate, monoammonium phosphate, hemisodium phosphate and the like. It will be understood that other water soluble compounds may also be used.
- a number of antibiotics in water soluble powder form may be also incorporated in the present carrier for release when in contact with the teeth and/ or gums.
- the resultant shape of the carrier has an l-beam configuration including vertically tapering inner walls 20 which permit more effective contact with the upper teeth and gum portions during treatment.
- the device Prior to introduction of device into the mouth of a patient, the device is first configurated such as illustrated in FIG. 3.
- the treatment is illustrated in FIG. 4 where the treating process is accomplished with slight pressure of the teeth into the intermediate ridge l6 while device 10 includes solvent of the teeth for the medicament. Because carrier 10 includes the solvent, i.e., the oral fluids in limited contact with the soluble medicament within the channel portions of the carrier, the activity is effectively released for application only to the teeth and gum areas.
- the present device Because of the inexpensive nature of the present device, it may be discarded after each treatment and is expecially adaptable to home usage. Also, it will be appreciated that the present device avoids the disadvantage of multiple step treatment required in prior art devices.
- a dental device which comprises a linear flexible foam carrier having an l-beam configuration with channel portions, and a water-soluble medicament disposed on walls of said channel portions for release when in contact with oral fluids whereby the said carrier is bent to an arcuate configuration adaptable to the oral cavity of a user.
- the medicament is a fluoride containing compound which releases fluoride in contact with teeth.
- the fluoride containing compound is selected from the group consisting of sodium fluoride, potassium fluoride, ammonium fluoride, sodium bifluoride, potassium bifluoride, ammonium bifluoride and sodium silicofluoride.
- a method of treating teeth which comprises applying a medicament to channel portions of a linear flexible foam carrier having an I-beam configuration, bending the carrier to an accurate configuration and inserting the carrier into the oral cavity, and releasing medicament in contact with teeth by contact of the medicament within the channel portions with oral fluids.
Abstract
A flexible foam I-beam shaped carrier is disclosed having a medicament disposed within channel portions thereof for release during dental treatment. The present invention provides a structure for dental treatment and is especially adaptable for home usage.
Description
I Umted States Patent 1 1111 3,844,286
Cowen Oct. 29, 1974 [54] RELEASABLE MEDICAMENT DENTAL 3,618,213 11/1971 Shepherd et al 32/2 CARRIER AND METHOD 3,688,406 9/1972 Porter et al 128/260 [76] Inventor: Samuel H. Cowen, Southfield, Mich.
Primary Examiner-Richard A. Gaudet Flledi g- 10, 1973 Assistant Examinerl-lenry J. Recla [21] Appl NO: 337,553 Attorney, Agent, or FirmEugene M. Bond [52] US. Cl. 128/260, 128/136 R [57] ABSTRACT 3 A flexible foam l-beam shaped carrier is disclosed 32/2 having a medicament disposed within channel portions thereof for release during dental treatment. The pres- [56] References Cited ent invention provides a structure for dental treatment UNITED STATES PATENTS and is especially adaptable for home usage. 3,567,823 3/1971 Yamaga et a1 128/260 6 Claims, 4 Drawing Figures PATENIEBBBIZE! m4 Y 3.844.286
MEDICAMENT FIG "2 MEDICAMENT I This invention relates to a foam carrier having a releasable medicament contained within channel portions thereof for use in dental treatment. More particularly the present invention provides a foam carrier which releases limited amounts of a medicament such as a fluoride, directly to the teeth in the oral cavity during dental treatment.
A variety of dental treatment devices are known in the art for treatment of diseases such as dental caries, pyorrhea, gingivitis and trench mouth. Proper treatment of these diseases requires that a medicament be in solution and in direct contact with the teeth and gums. Typically, prior art devices provide means for jacketing treating solutions thus requiring separate application of solution and device. Also, controlled amounts of solution must be employed which is difficult in actual practice with the likelihood of spillage being significant.
More importantly, because of the requirement in prior art devices that the treating solution be separately prepared at the use location, it becomes impractical to apply such devices for home usage since such would require a patient to formulate the treating solution. Also, in instances when the patient is required to prepare the treating solution, the likelihood of either under dosage or over dosage treatments becomes significant.
Liquid acid phosphate-fluoride solutions have been clinically employed by dentists for topical application to teeth for the purpose of preventing or reducing dental caries. Clinical studies have shown the cariesreducing effectiveness of a single application of liquid acid phosphate-fluoride preparations. in practice these solutions have been applied by the dentist who makes a wax impression of the patients teeth which is used as a mold in which the liquid acid phosphate-fluoride preparation is placed before applying the impression bring the preparation into intimate contact with the teeth. However, this practice has been found unsatisfactory in that the available liquid preparations tend to run out from the wax impression, particularly where the teeth in the lower jaw are being treated.
contact is achieved between the liquid preparation and all surfaces of the teeth..
'Tt has nowEeTfWncrtnarby pracnce orrrrepres'enr invention, there is provided a new improved dental device having a pre-disposed medicament in non-liquid state dispersed such that active portions thereof may be controllably released for dental treatment by the fluids of the oral cavity adjacent to the surfaces of the teeth, and by a slight bite pressure into the foam carrier. Thus, the present device overcomes numerous difficulties and disadvantages of prior art devices which require separate application of treating solution and means for holding the solution in relation to the teeth and gums being treated.
vice with pre-determined amount of medicament in proper location is readily adaptable to home usage.
Practice of the present invention will become more apparent from the following detailed description taken in conjunction with the figures wherein:
FIG. 1 illustrates in perspective the present flexible foam l-beam shape carrier as it normally appears;
FIG. 2 is a side elevational view of the present carrier into which is channeled a medicament disposed for subsequent release;
FIG. 3 illustrates the present device in the configuration prior to introduction into the mouth of a patient;
and
FIG. 4 illustrates in partial section, the present device in contact with teeth and gum tissue during treatment.
Referring to the drawings, FIGS. 1 and 2 illustrate foam carrier 10 having side walls 12 and 14 joined by intermediate ridge portion 16. In FIG. 2, a medicament is disposed onto the foam carrier within channel portions defined by walls 20, by most any convenient means.
The medicament may be disposed onto the channel portions of the carrier by a number of different means. For example, finely divided particles of medicament may be incorporated in a soluble adhesive. Alternately, a solution of medicament may be prepared and dried on the foam carrier.
The present carrier may be made of open cell or closed cell foam cushioning material. Such material includes for example, latex, polystyrene, polyurethane or related open cell foams. Polyurethane foam has been 5 found to be a good open cell material for use in making the carrier and is preferred.
The fluoride compound component must be substantially soluble in water and ionize by fluids adjacent the teeth to provide a source of fluoride ions. Fluoride 0 compounds which have been found satisfactory include sodium fluoride, potassium fluoride, ammonium fluoride, sodium bifluoride, potassium bifluoride, ammonium bifluoride and sodium silicofluoride. Other fluoride compounds including combined chemical com- 5 pounds which yield fluoride ions in dilute aqueous solu- Generally stated, the present dental carrier has a flex- 6O ible foam l-beam configuration with medicament disposed on channel portions thereof. The device is conveniently prepared in a continuous strip which, because of the flexibility of the foam, may be readily severed to tions may be also utilized. The device of this invention contains a sufficient amount of such a fluoride compound to provide about 0.25 to about 5.0 percent of fluoride ions and preferably about 1.25 percent in contact with the teeth.
When acid phosphate is used, it must also be substantially water-soluble and provide the desired phosphate ions. Examples of such acid phosphate compounds which may be used include orthophosphoric acid, monosodium phosphate, monopotassium phosphate, disodium phosphate, dipotassium phosphate, monoammonium phosphate, hemisodium phosphate and the like. It will be understood that other water soluble compounds may also be used.
A number of antibiotics in water soluble powder form may be also incorporated in the present carrier for release when in contact with the teeth and/ or gums.
The resultant shape of the carrier has an l-beam configuration including vertically tapering inner walls 20 which permit more effective contact with the upper teeth and gum portions during treatment.
Prior to introduction of device into the mouth of a patient, the device is first configurated such as illustrated in FIG. 3.
The treatment is illustrated in FIG. 4 where the treating process is accomplished with slight pressure of the teeth into the intermediate ridge l6 while device 10 includes solvent of the teeth for the medicament. Because carrier 10 includes the solvent, i.e., the oral fluids in limited contact with the soluble medicament within the channel portions of the carrier, the activity is effectively released for application only to the teeth and gum areas.
Because of the inexpensive nature of the present device, it may be discarded after each treatment and is expecially adaptable to home usage. Also, it will be appreciated that the present device avoids the disadvantage of multiple step treatment required in prior art devices.
It will be further apparent from the foregoing that numerous variations may be made in the present invention without departing from the scope as defined.
What is claimed is:
1. A dental device which comprises a linear flexible foam carrier having an l-beam configuration with channel portions, and a water-soluble medicament disposed on walls of said channel portions for release when in contact with oral fluids whereby the said carrier is bent to an arcuate configuration adaptable to the oral cavity of a user.
2. The device of claim 1 wherein the medicament is a fluoride containing compound which releases fluoride in contact with teeth.
3. The device of claim 2 wherein the fluoride containing compound is selected from the group consisting of sodium fluoride, potassium fluoride, ammonium fluoride, sodium bifluoride, potassium bifluoride, ammonium bifluoride and sodium silicofluoride.
4. The device of claim 2 wherein the amount of medicament is sufficient to provide about 0.25 percentto about 5.0 percent by weight of fluoride ions in contact with teeth.
5. The device of claim 4 wherein the amount of medicament is about 1.25 percent by weight in contact with teeth.
6. A method of treating teeth which comprises applying a medicament to channel portions of a linear flexible foam carrier having an I-beam configuration, bending the carrier to an accurate configuration and inserting the carrier into the oral cavity, and releasing medicament in contact with teeth by contact of the medicament within the channel portions with oral fluids.
1M 05am!) STATES PATENT OFFICE CERTIFICATE CORRECTIQN- Patent No. .3 36 I i I DaredOctOberZ'QQ: lnventoflsi) Samuel H. Cowen and Jack Nater Q It is Certified that error appears in the above-identified patent and that said LetterePatent are hereby corrected as shown below:
Inventor on Letters Patent now reading: i
Samn'el H. Cowen 24513 Custis Southfield, Michigan 48075 Should be corrected to read:
Sainu'ei H. Cowen 24513.;Custis Southfield, Michigan 48075 I AND Jack Nater l220-Morse Street Royal Oak, Michigan, 48000 signed an'd sealed this 13th day of May 1975.
(sFAL) Attest:
, C. MARSHALL DANN RUTH C. MASON I Commissioner of Patents Attesting Officer and Trademarks
Claims (6)
1. A DENTAL DEVICE WHICH COMPRISES A LINEAR FLEXIBLE FOAM CARRIER HAVING AN I-BEAM CONFIGURATION WITH CHANNEL PORTIONS, AND A WATER-SOLUBLE MEDICAMENT DISPOSED ON WALLS OF SAID CHANNEL PORTIONS FOR RELEASE WHEN IN CONTACT WITH ORAL FLUIDS WHEREBY THE SAID CARRIER IS BENT TO AN ARCUATE CONFIGURATION ADAPTABLE TO THE ORAL CAVITY OF A USER.
2. The device of claim 1 wherein the medicament is a fluoride containing compound which releases fluoride in contact with teeth.
3. The device of claim 2 wherein the fluoride containing compound is selected from the group consisting of sodium fluoride, potassium fluoride, ammonium fluoride, sodium bifluoride, potassium bifluoride, ammonium bifluoride and sodium silicofluoride.
4. The device of claim 2 wherein the amount of medicament is sufficient to provide about 0.25 percent to about 5.0 percent by weight of fluoride ions in contact with teeth.
5. The device of claim 4 wherein the amount of medicament is about 1.25 percent by weight in contact with teeth.
6. A method of treating teeth which comprises applying a medicament to channel portions of a linear flexible foam carrier having an I-beam configuration, bending the carrier to an accurate configuration and inserting the carrier into the oral cavity, and releasing medicament in contact with teeth by contact of the medicament within the channel portions with oral fluids.
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US00387553A US3844286A (en) | 1973-08-10 | 1973-08-10 | Releasable medicament dental carrier and method |
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US00387553A US3844286A (en) | 1973-08-10 | 1973-08-10 | Releasable medicament dental carrier and method |
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Cited By (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3964164A (en) * | 1973-02-05 | 1976-06-22 | Hesselgren Sven Gunnar | Method of applying preventive and therapeutic agents |
EP0092329A2 (en) * | 1982-04-07 | 1983-10-26 | Bernard Paul Philippe Feinmann | Improved material and method for dentistry |
US4609348A (en) * | 1985-07-12 | 1986-09-02 | James R. Rehak | Mouth and cheek protector |
WO1989010153A1 (en) * | 1988-04-26 | 1989-11-02 | Newman Martin H | Therapeutic dental appliance |
US4892736A (en) * | 1983-10-07 | 1990-01-09 | The Forsyth Dental Infirmary For Children | Intra-pocket drug delivery devices for treatment of periodontal diseases |
US5082007A (en) * | 1990-01-24 | 1992-01-21 | Loren S. Adell | Multi-laminar mouthguards |
US5129824A (en) * | 1989-12-21 | 1992-07-14 | Keller Duane C | Method for treating periodontal disease |
USRE34196E (en) * | 1988-08-23 | 1993-03-16 | Dunhall Pharmaceuticals, Inc. | Method and material for brightening teeth |
US5234342A (en) * | 1990-03-22 | 1993-08-10 | Ultradent Products, Inc. | Sustained release method for treating teeth surfaces |
US5310563A (en) * | 1991-10-25 | 1994-05-10 | Colgate-Palmolive Company | Dental material and method for applying preventative and therapeutic agents |
EP0597933A1 (en) * | 1991-07-18 | 1994-05-25 | Gillette Canada Inc. | Dental tray |
US5376006A (en) * | 1990-03-22 | 1994-12-27 | Ultradent Products, Inc. | Dental bleaching compositions and methods for bleaching teeth surfaces |
US5406963A (en) * | 1989-03-27 | 1995-04-18 | Adell; Loren S. | Mouthguard |
US5409631A (en) * | 1990-03-22 | 1995-04-25 | Ultradent Products | Dental bleaching compositions and methods for bleaching teeth surfaces |
US5575654A (en) * | 1992-11-24 | 1996-11-19 | Fontenot; Mark G. | Apparatus and method for lightening teeth |
US5582560A (en) * | 1994-09-21 | 1996-12-10 | Magnuson; Gerald L. | Jaw exerciser |
US5851512A (en) * | 1990-03-22 | 1998-12-22 | Ultradent Products, Inc. | Dental compositions having a sticky matrix material for treating sensitive teeth |
US5855904A (en) * | 1994-11-01 | 1999-01-05 | Dong Kook Pharmaceutical Co., Ltd. | Biodegradable sustained release preparation for treating periodontitis |
US5855870A (en) * | 1990-03-22 | 1999-01-05 | Ultradent Products, Inc. | Method for treating sensitive teeth |
US5985249A (en) * | 1990-03-22 | 1999-11-16 | Ultradent Products, Inc. | Sticky dental compositions for adhering a passive-type dental tray over a person's teeth |
US6036943A (en) * | 1990-03-22 | 2000-03-14 | Ultradent Products, Inc. | Methods for treating a person's teeth using sticky dental compositions in combination with passive-type dental trays |
US6036487A (en) * | 1994-02-23 | 2000-03-14 | Fastcote Pty Ltd. | Mouthguard blank and mouthguard |
USRE37382E1 (en) | 1996-07-15 | 2001-09-18 | Alayne Yates | Gum pad for mucosal delivery of medication |
US6306370B1 (en) | 1997-05-30 | 2001-10-23 | Ultradent Products, Inc. | Compositions and methods for whitening and desensitizing teeth |
US6309625B1 (en) | 1998-11-12 | 2001-10-30 | Ultradent Products, Inc. | One-part dental compositions and methods for bleaching and desensitizing teeth |
US6322772B1 (en) * | 1999-07-22 | 2001-11-27 | Janet Margaret Wehrli | Methodology for treatment of the dental arches and periodontal tissue |
US6475471B1 (en) * | 1999-07-22 | 2002-11-05 | Janet M. Wehrli | System and method for applying oral fluid absorbing material to dental arches, with application in treatment of periodontal gum disease |
US20030059381A1 (en) * | 1997-06-06 | 2003-03-27 | Goodhart Lesle Marie | Structures and compositions increasing the stability of peroxide actives |
US6551579B2 (en) | 1997-06-06 | 2003-04-22 | The Procter & Gamble Company | Delivery systems for a tooth whitener |
US6582708B1 (en) | 2000-06-28 | 2003-06-24 | The Procter & Gamble Company | Tooth whitening substance |
WO2003092530A1 (en) * | 2002-05-03 | 2003-11-13 | Schaetzner Reinhard | Device for applying a dental treatment agent to the teeth and/or gums |
US6685923B2 (en) | 2001-01-25 | 2004-02-03 | Dentsply Research & Development Corp. | Tooth whitening material and method of whitening teeth |
US6685922B2 (en) | 2000-03-23 | 2004-02-03 | Dentsply International Inc. | Tooth whitening material and method of whitening teeth |
US6884426B2 (en) | 1997-06-06 | 2005-04-26 | The Procter & Gamble Co. | Methods for whitening teeth |
US20050095561A1 (en) * | 2002-05-03 | 2005-05-05 | Reinhard Schatzner | Device for applying dental treatment agent to teeth and/or gums |
US6949240B2 (en) | 2002-05-23 | 2005-09-27 | The Procter & Gamble Company | Tooth whitening products |
US7029690B1 (en) * | 1999-07-22 | 2006-04-18 | Clinically Clean Inc. | Oral fluid absorbing compositions and system for application thereof in a method of dental arch treatment |
US20070196287A1 (en) * | 1998-11-12 | 2007-08-23 | Ultradent Products, Inc. | Methods for bleaching and desensitizing teeth |
US20100000543A1 (en) * | 2002-11-06 | 2010-01-07 | Resmed Limited | Mask and components thereof |
US20100285424A1 (en) * | 2008-01-30 | 2010-11-11 | Burgio Paul A | Dental applicator device |
US20100326450A1 (en) * | 2009-06-30 | 2010-12-30 | Invention Dynamics, Llc | Cheek Saver |
US7955591B1 (en) | 1999-07-22 | 2011-06-07 | Wehrli Janet M | Oral fluid absorbing compositions and system for application thereof in a method of dental arch treatment and teeth recalcification |
US20120199138A1 (en) * | 2011-02-08 | 2012-08-09 | Hannapel Eric D | Orthodontic appliance shield |
FR3011477A1 (en) * | 2013-10-07 | 2015-04-10 | Charlotte Claudie Paule Wils | EXERCISE APPARATUS FOR THE LIPS AND MUSCLES OF THE ORBICULAR REGION OF THE MOUTH |
US9554976B2 (en) | 2002-09-11 | 2017-01-31 | The Procter & Gamble Company | Tooth whitening product |
US10285915B2 (en) | 2012-10-17 | 2019-05-14 | The Procter & Gamble Company | Strip for the delivery of an oral care active and methods for applying oral care actives |
IT201900018752A1 (en) | 2019-10-14 | 2021-04-14 | Alessandro Tosetti | COMPOSITION BASED ON ESSENTIAL OILS FOR DENTAL USE FOR THE TREATMENT OF PERIODONTITIS AND PERIMPLANT MUCOSITE |
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Cited By (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3964164A (en) * | 1973-02-05 | 1976-06-22 | Hesselgren Sven Gunnar | Method of applying preventive and therapeutic agents |
EP0092329A2 (en) * | 1982-04-07 | 1983-10-26 | Bernard Paul Philippe Feinmann | Improved material and method for dentistry |
EP0092329A3 (en) * | 1982-04-07 | 1984-12-05 | Bernard Paul Philippe Feinmann | Improved material and method for dentistry |
US4892736A (en) * | 1983-10-07 | 1990-01-09 | The Forsyth Dental Infirmary For Children | Intra-pocket drug delivery devices for treatment of periodontal diseases |
US4609348A (en) * | 1985-07-12 | 1986-09-02 | James R. Rehak | Mouth and cheek protector |
WO1989010153A1 (en) * | 1988-04-26 | 1989-11-02 | Newman Martin H | Therapeutic dental appliance |
US4944947A (en) * | 1988-04-26 | 1990-07-31 | Newman Martin H | Therapeutic dental appliance |
USRE34196E (en) * | 1988-08-23 | 1993-03-16 | Dunhall Pharmaceuticals, Inc. | Method and material for brightening teeth |
US5406963A (en) * | 1989-03-27 | 1995-04-18 | Adell; Loren S. | Mouthguard |
US5330357A (en) * | 1989-12-21 | 1994-07-19 | Keller Duane C | System for treating periodontal disease |
US5129824A (en) * | 1989-12-21 | 1992-07-14 | Keller Duane C | Method for treating periodontal disease |
US5082007A (en) * | 1990-01-24 | 1992-01-21 | Loren S. Adell | Multi-laminar mouthguards |
US6183251B1 (en) | 1990-03-22 | 2001-02-06 | Ultradent Products, Inc. | Scalloped dental trays for use in treating teeth with sticky dental compositions |
US6036943A (en) * | 1990-03-22 | 2000-03-14 | Ultradent Products, Inc. | Methods for treating a person's teeth using sticky dental compositions in combination with passive-type dental trays |
US5376006A (en) * | 1990-03-22 | 1994-12-27 | Ultradent Products, Inc. | Dental bleaching compositions and methods for bleaching teeth surfaces |
US5234342A (en) * | 1990-03-22 | 1993-08-10 | Ultradent Products, Inc. | Sustained release method for treating teeth surfaces |
US6086855A (en) * | 1990-03-22 | 2000-07-11 | Ultradent Products, Inc. | Methods for making scalloped dental trays for use in treating teeth with sticky dental compositions |
US5409631A (en) * | 1990-03-22 | 1995-04-25 | Ultradent Products | Dental bleaching compositions and methods for bleaching teeth surfaces |
US5985249A (en) * | 1990-03-22 | 1999-11-16 | Ultradent Products, Inc. | Sticky dental compositions for adhering a passive-type dental tray over a person's teeth |
US5855870A (en) * | 1990-03-22 | 1999-01-05 | Ultradent Products, Inc. | Method for treating sensitive teeth |
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