US3871772A - Eye examining instrument aligning means and method therefor - Google Patents

Eye examining instrument aligning means and method therefor Download PDF

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US3871772A
US3871772A US353648A US35364873A US3871772A US 3871772 A US3871772 A US 3871772A US 353648 A US353648 A US 353648A US 35364873 A US35364873 A US 35364873A US 3871772 A US3871772 A US 3871772A
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eye
instrument
image forming
optical axis
forming means
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Charles R Munnerlyn
Robert C Moore
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Cooper Companies Inc
Tropel Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A61B3/152—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for aligning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/26—Measuring arrangements characterised by the use of optical techniques for measuring angles or tapers; for testing the alignment of axes
    • G01B11/27—Measuring arrangements characterised by the use of optical techniques for measuring angles or tapers; for testing the alignment of axes for testing the alignment of axes

Definitions

  • Such an eye 351/16 356/153 172 viewer is associated with an eye examining instrument for aligning and positioning the instrument relative to [56] References Cited the eye by in w r tse th f h instrument on the eye and the centering of the image UNITED STATES PATENTS of the eye in the field of view of the eye viewer.
  • the invention involves recognition of the advantages of a way to view the eye with infra red light invisible to the eye and not producing reflex reactions.
  • the invention also proposes use of an infra red eye viewer for aligning an eye examining instrument, and the invention aims at simplicity, economy, reliability, and practicality in an eye viewer suitable for many purposes.
  • the inventive eye viewer uses a source of infra red light directed on the eye, an image intensifier, means for focusing reflected infra red light from the eye on the image intensifier, and means for viewing the image intensifier for observing a visible image of the eye.
  • a viewer is combined with an eye-examining instrument for observing the alignment of the instrument with the eye being examined, and the invention includes an instrument alignment method involving focusing the re flected infra red light from the eye on an image intensifier off the axis of the instrument and viewing the image of the eye for adjusting the alignment and spacing of the instrument.
  • FIG. 1 is a schematic view of an eye viewer according to the invention
  • FIG. 2 is a schematic, elevational view of a preferred embodiment of the inventive eye viewer associated with an eye examining instrument
  • FIG. 3 is a schematic elevational view of another preferred embodiment of the inventive eye viewer associated with an eye examining instrument.
  • FIG. 4 is a view of an eye through the inventive eye viewer.
  • FIG. 1 A simplified, schematic form of the inventive viewer is shown in FIG. 1 and includes a housing 11 holding a source of infra red light 13. Light from source 13 passes'through a lens 14 that can include a filter and is then directed outward by beam splitter 15. Reflected light passes back through beam splitter 15 and is focused by lens 16 on image intensifier 17 which is viewed through an eyepiece 18.
  • a lens 14 that can include a filter and is then directed outward by beam splitter 15.
  • Reflected light passes back through beam splitter 15 and is focused by lens 16 on image intensifier 17 which is viewed through an eyepiece 18.
  • infra red light directed onto an eye is not visible to the eye being examined, and reflected infra red light from the eye being examined would not be visible to the examiner except that the inventive eye viewer makes this possible through use of image intensifier 17.
  • a basic viewer such as simplified in FIG. 1 can be used in association with other eye examining equipment as illustrated in FIGS. 2 and 3.
  • Eye examining instrument 20 of FIG. 2 can be any through eyepiece 23, and onto eye 22.
  • Instrument 20 is adjustable on x, y and z axes as shown by the arrows for registering optical axis 21 accurately with eye 22 and spacing eye 22 accurately from eyepiece 23.
  • the inventive eye viewer 25 is supported on instrument 20 and includes an eyepiece 26 for viewing an image intensifier 27 on which an image of eye 22 is focused by objective 28 receiving light from mirror 29 through aperture plate 30.
  • This arrangement uses reflected infra red light from eye 22 off optical axis 21 to make an image of eye 22 visible to an observer 31.
  • the field of view of image intensifier 27 is fixed by objective 28, mirror 29, and aperture plate 30 relative to instrument 20 so that the field of view of image intensifier 27 intersects optical axis 21 at the region where eye 22 should be positioned for proper alignment and spacing from instrument 20 and eyepiece 23.
  • the region of eye 22 illuminated by light from the optical system of instrument 20 can be viewed by observer 31 via image intensifier 27, and instrument 20 can be moved transversely to axis 21 until the illumieye-examining instrument that would benefit from use nated area is centered on the pupil of eye 22. This ensures that eye 22 is centered on optical axis 21.
  • the distance of eye 22 from eyepiece 23 can also be adjusted by centering the image of eye 22 in the field of view of image intensifier 27. If eye 22 is too close to eyepiece 23, the upper region of eye 22 will be centered in the field of view of image intensifier 27, and if eye 22 is spaced too far from eyepiece 23, the lower region of eye 22 will be centered inthe field of view of image intensifier 27.
  • an appropriate axial adjustment of instrument 20 can then be made to center eye 22 in the field of view of image intensifier 27 for perfect spacing as well as alignment of eye 22 relative to instrument 20.
  • a horizontal mark 32 is preferably centered on or adjacent image intensifier 27 so that instrument 20 can be adjusted axially to center line 32 through the viewed image 33 of an eye 32 as shown in FIG. 4. With line 32 centered on eye image 33 as illustrated, and the illumination from instrument 20 observed as centered on the pupil of eye image 33, instrument 20 is accurately aligned and positioned relative to eye 22.
  • an eye viewer can view the eye from below or from the side as easily as from above to accomplish the same aligning and positioning.
  • Instrument 40 of FIG. 3 is similar to instrument 20 in having an optical path 41 registered with eye 42 through eyepiece 43. Infra red light reflected from eye 42 travels back along optical path 41 for detection by instrument 40, and eye viewer 35 is movable transversely of optical path 41 for aligning instrument 40.
  • a mirror or beam splitter 36 is movable into and retractable out of optical path 41, and viewer 35 and element 36 can be positioned as illustrated to intercept infra red light reflected from eye 42. Reflected light diverted by beam splitter or mirror 36 is focused by objective 37 on image intensifier 38 and viewed through eyepiece 39 by observer 34.
  • Instrument 40 can be moved on an .r or y axis to center the illumination from instrument 40 on the pupil of eye 42. After alignment, viewer 35 is retracted to withdraw mirror or beam splitter 36 from optical path 41 to allow examination of eye 42.
  • the arrangement of FIG. 3 is somewhat simpler than FIG. 2 but cannot determine the spacing of eye 42 from eyepiece 43.
  • An eye viewer for aligning the optical axis of an eye examining instrument with an eye and spacing said instrument a predetermined distance from said eye, said viewer comprising:
  • the viewer of claim 1 including a mark fixed relative to said image forming means to aid in said centering of said eye in said field of view of said image forming means.

Abstract

An eye viewer uses a source of infra red light directed on the eye, an image intensifier, means for focusing reflected infra red light from the eye on the image intensifier, and means for viewing the image intensifier for observing a visible image of the eye. Such an eye viewer is associated with an eye examining instrument for aligning and positioning the instrument relative to the eye by viewing the centering of the light from the instrument on the eye and the centering of the image of the eye in the field of view of the eye viewer.

Description

United States Patent 1191 1111 3,871,772 Munnerlyn et a1. [4 Mar. 18, 1975 [54] EYE EXAMINING INSTRUMENT ALIGNING 3,518,005 6/1970 Weber 356/172 X MEANS AND METHOD THEREFOR 3,572,909 3/1971 Van Patten 351/9 X g 3,600,098 8/1971 Mohrman 351/6 X [75] Inventors: Charles R- Munnerly Falrport; 3,640,610 2/1972 Nupuf 351/39 x Robert C. Moore, Rochester, both of Primary Examiner-Paul A. Sacher [73] Assignee: Tropel, lnc., Fairport, NY. g kf Agent Firmcumpstom Shaw &
tep ens [22] Filed: Apr. 23, 1973 [21] Appl. No; 353,648 [57] ABSTRACT An eye viewer uses a source of infra red light directed 52 us. c1 356/153, 351/1 351/6, the image intensifier means for focusing 351/13 351/39 556/172 reflected infra red light from the eye on the image in- [511 Int CL Golb 11/27, 3/00 tensifier, and means for viewing the image intensifier [58] Field of Search 350/2. 351/], 6, 9 13, for observing a visible image of the eye. Such an eye 351/16 356/153 172 viewer is associated with an eye examining instrument for aligning and positioning the instrument relative to [56] References Cited the eye by in w r tse th f h instrument on the eye and the centering of the image UNITED STATES PATENTS of the eye in the field of view of the eye viewer. 2,536,305 1/1951 Morton 351/9 3,407,302 10/1968 Bouwers 350/2 X 3 Claims, 4 Drawing Figures I I 1 29 (O 1 50 EYE EXAMINING INSTRUMENT 23 PATENTEU MR1 81975 EYE EXAMlNING INSTRUMENT 36 EYE EXAMININGYINSTRUMENT EYE EXAMINING INSTRUMENT ALIGNING MEANS AND METHOD THEREFOR THE INVENTIVE IMPROVEM ENT Many different instruments and examination procedures require viewing of the eye, and yet the visible light .used in illuminating the eye is also visible to the eye being examined, and causes various problems including constriction of the pupil of the eye. The invention involves recognition of the advantages of a way to view the eye with infra red light invisible to the eye and not producing reflex reactions. The invention also proposes use of an infra red eye viewer for aligning an eye examining instrument, and the invention aims at simplicity, economy, reliability, and practicality in an eye viewer suitable for many purposes.
SUMMARY OF THE INVENTION The inventive eye viewer uses a source of infra red light directed on the eye, an image intensifier, means for focusing reflected infra red light from the eye on the image intensifier, and means for viewing the image intensifier for observing a visible image of the eye. Such a viewer is combined with an eye-examining instrument for observing the alignment of the instrument with the eye being examined, and the invention includes an instrument alignment method involving focusing the re flected infra red light from the eye on an image intensifier off the axis of the instrument and viewing the image of the eye for adjusting the alignment and spacing of the instrument.
DRAWINGS FIG. 1 is a schematic view of an eye viewer according to the invention;
FIG. 2 is a schematic, elevational view ofa preferred embodiment of the inventive eye viewer associated with an eye examining instrument;
FIG. 3 is a schematic elevational view of another preferred embodiment of the inventive eye viewer associated with an eye examining instrument; and
FIG. 4 is a view of an eye through the inventive eye viewer.
DETAILED DESCRIPTION A simplified, schematic form of the inventive viewer is shown in FIG. 1 and includes a housing 11 holding a source of infra red light 13. Light from source 13 passes'through a lens 14 that can include a filter and is then directed outward by beam splitter 15. Reflected light passes back through beam splitter 15 and is focused by lens 16 on image intensifier 17 which is viewed through an eyepiece 18.
The infra red light directed onto an eye is not visible to the eye being examined, and reflected infra red light from the eye being examined would not be visible to the examiner except that the inventive eye viewer makes this possible through use of image intensifier 17. A basic viewer such as simplified in FIG. 1 can be used in association with other eye examining equipment as illustrated in FIGS. 2 and 3.
Eye examining instrument 20 of FIG. 2 can be any through eyepiece 23, and onto eye 22. Instrument 20 is adjustable on x, y and z axes as shown by the arrows for registering optical axis 21 accurately with eye 22 and spacing eye 22 accurately from eyepiece 23.
The inventive eye viewer 25 is supported on instrument 20 and includes an eyepiece 26 for viewing an image intensifier 27 on which an image of eye 22 is focused by objective 28 receiving light from mirror 29 through aperture plate 30. This arrangement uses reflected infra red light from eye 22 off optical axis 21 to make an image of eye 22 visible to an observer 31. The field of view of image intensifier 27 is fixed by objective 28, mirror 29, and aperture plate 30 relative to instrument 20 so that the field of view of image intensifier 27 intersects optical axis 21 at the region where eye 22 should be positioned for proper alignment and spacing from instrument 20 and eyepiece 23.
The region of eye 22 illuminated by light from the optical system of instrument 20 can be viewed by observer 31 via image intensifier 27, and instrument 20 can be moved transversely to axis 21 until the illumieye-examining instrument that would benefit from use nated area is centered on the pupil of eye 22. This ensures that eye 22 is centered on optical axis 21. The distance of eye 22 from eyepiece 23 can also be adjusted by centering the image of eye 22 in the field of view of image intensifier 27. If eye 22 is too close to eyepiece 23, the upper region of eye 22 will be centered in the field of view of image intensifier 27, and if eye 22 is spaced too far from eyepiece 23, the lower region of eye 22 will be centered inthe field of view of image intensifier 27. An appropriate axial adjustment of instrument 20 can then be made to center eye 22 in the field of view of image intensifier 27 for perfect spacing as well as alignment of eye 22 relative to instrument 20. To aid in centering the image of the eye in the field of view of intensifier 27, a horizontal mark 32 is preferably centered on or adjacent image intensifier 27 so that instrument 20 can be adjusted axially to center line 32 through the viewed image 33 of an eye 32 as shown in FIG. 4. With line 32 centered on eye image 33 as illustrated, and the illumination from instrument 20 observed as centered on the pupil of eye image 33, instrument 20 is accurately aligned and positioned relative to eye 22. Of course an eye viewer can view the eye from below or from the side as easily as from above to accomplish the same aligning and positioning.
Instrument 40 of FIG. 3 is similar to instrument 20 in having an optical path 41 registered with eye 42 through eyepiece 43. Infra red light reflected from eye 42 travels back along optical path 41 for detection by instrument 40, and eye viewer 35 is movable transversely of optical path 41 for aligning instrument 40. A mirror or beam splitter 36 is movable into and retractable out of optical path 41, and viewer 35 and element 36 can be positioned as illustrated to intercept infra red light reflected from eye 42. Reflected light diverted by beam splitter or mirror 36 is focused by objective 37 on image intensifier 38 and viewed through eyepiece 39 by observer 34.
Instrument 40 can be moved on an .r or y axis to center the illumination from instrument 40 on the pupil of eye 42. After alignment, viewer 35 is retracted to withdraw mirror or beam splitter 36 from optical path 41 to allow examination of eye 42. The arrangement of FIG. 3 is somewhat simpler than FIG. 2 but cannot determine the spacing of eye 42 from eyepiece 43.
Persons wishing to practice the invention should remember that other embodiments and variations can be adapted to particular circumstances. Even though one point of view is necessarily chosen in describing and defining the invention, this should not inhibit broader or related embodiments going beyond the semantic orientation of this application but falling within the spirit of the invention. For example, those skilled in the art will understand the various arrangements of mirrors, beam splitters, focusing lenses, eyepieces, and other optical elements cooperating with an image intensifier for viewing an eye illuminated by infrared light for various purposes.
I claim:
1. An eye viewer for aligning the optical axis of an eye examining instrument with an eye and spacing said instrument a predetermined distance from said eye, said viewer comprising:
a. a source of radiant energy;
b. means for directing a beam of said radiant energy on said eye along said optical axis;
c. means mounted on said instrument off said optical axis for forming a viewable image from said radiant energy;
(1. means for focusing radiant energy reflected from said eye at an acute angle from said optical axis and onto said image forming means so the field of view of said image forming means intersects said optical axis at said predetermined distance from said eye;
e. means for adjusting said instrument transversely of said eye for centering said radiant energy beam on said eye as viewed in said image forming means to align said beam with said eye; and
f. means for adjusting said instrument in the direction LII LII
of said optical axis to center said image of said eye in said field of view of said image forming means for spacing said instrument said predetermined distance from said eye.
2. The viewer of claim 1 including a mark fixed relative to said image forming means to aid in said centering of said eye in said field of view of said image forming means.
3. A method of aligning and spacing an instrument relative to an eye for objectively measuring the refractive error of said eye by directing a beam of radiant energy along an optical axis onto said eye and monitoring the radiant energy reflected from the retina of said eye back along said optical axis, said aligning and spacing method comprising:
a. gathering radiant energy reflected from said eye at an acute angle from said optical axis;
b. focusing said gathered reflected radiant energy on an image forming means;
c. fixing the field of view of said image forming means to intersect said optical axis of said instrument at a predetermined distance from said instrument;
d. viewing the image of said eye formed by said image forming means;
e. adjusting said instrument transversely of said eye until said radiant energy beam is centered on said eye as observed on said image forming means; and
f. adjusting the spacing of said instrument from said eye by moving said instrument and said image forming means together until said image of said eye is centered in said field viewed by said image forming means.

Claims (3)

1. An eye viewer for aligning the optical axis of an eye examining instrument with an eye and spacing said instrument a predetermined distance from said eye, said viewer comprising: a. a source of radiant energy; b. means for directing a beam of said radiant energy on said eye along said optical axis; c. means mounted on said instrument off said optical axis for forming a viewable image from said radiant energy; d. means for focusing radiant energy reflected from said eye at an acute angle from said optical axis and onto said image forming means so the field of view of said image forming means intersects said optical axis at said predetermined distance from said eye; e. means for adjusting said instrument transversely of said eye for centering said radiant energy beam on said eye as viewed in said image forming means to align said beam with said eye; and f. means for adjusting said instrument in the direction of said optical axis to center said image of said eye in said field of view of said image forming means for spacing said instrument said predetermined distance from said eye.
2. The viewer of claim 1 including a mark fixed relative to said image forming means to aid in said centering of said eye in said field of view of said image forming means.
3. A method of aligning and spacing an instrument relative to an eye for objectively measuring the refractive error of said eye by directing a beam of radiant energy along an optical axis onto said eye and monitoring the radiant energy reflected from the retina of said eye back along said optical axis, said aligning and spacing method comprising: a. gathering radiant energy reflected from said eye at an acute angle from said optical axis; b. focusing said gathered reflected radiant energy on an image forming means; c. fixing the field of view of said image forming means to intersect said optical axis of said instrument at a predetermined distance from said instrument; d. viewing the image of said eye formed by said image forming means; e. adjusting said instrument transversely of said eye until said radiant energy beam is centered on said eye as observed on said image forming means; and f. adjusting the spacing of said instrument from said eye by moving said instrument and said image forming means together until said image of said eye is centered in said field viewed by said image forming means.
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Cited By (20)

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JPS53126792A (en) * 1977-04-12 1978-11-06 Canon Kk Ophthalmologic device having alignment system
US4180323A (en) * 1977-09-30 1979-12-25 American Optical Corporation Alignment system and ophthalmic instrument incorporating the same
JPS5542624A (en) * 1978-09-20 1980-03-26 Canon Kk Automatic eye refraction measuring system
US4196979A (en) * 1976-10-16 1980-04-08 Canon Kabushiki Kaisha Method and device for detecting distance between eye-examining instrument and eye
JPS5554934A (en) * 1979-10-26 1980-04-22 Canon Kk Automatic ocular refraction meter
US4253743A (en) * 1977-05-17 1981-03-03 Canon Kabushiki Kaisha Eye testing instrument
US4277150A (en) * 1977-08-24 1981-07-07 Tokyo Kogaku Kikai Kabushiki Kaisha Eye refractmeter
US4306778A (en) * 1978-11-13 1981-12-22 Tokyo Kogaku Kikai Kabushiki Kaisha Eye refractmeters using infrared rays
US4364646A (en) * 1979-03-13 1982-12-21 Nippon Kogaku K.K. Position adjusting device for ophthalmologic instrument
US4397182A (en) * 1981-03-31 1983-08-09 The Babcock & Wilcox Company Method of aligning a water level indicator having a remote and a local readout display
US4407572A (en) * 1980-06-12 1983-10-04 Humphrey Instruments, Inc. Keratometer
US4923297A (en) * 1986-06-23 1990-05-08 Eyedentify, Inc. Optical alignment system
EP0437504A1 (en) * 1988-10-04 1991-07-24 Allergan Humphery Range detector for eye instrument having interrogating beam.
EP0589825A2 (en) * 1992-09-25 1994-03-30 OPTIKO SCIENTIFIC Ltd. Ophthalmologic examination and/or treatment apparatus
US5585873A (en) * 1991-10-11 1996-12-17 Alcon Laboratories, Inc. Automated hand-held keratometer
WO1998048691A1 (en) * 1997-04-25 1998-11-05 Matthew Colvard Method for observing the eye in minimal light
WO1999059485A1 (en) * 1998-05-18 1999-11-25 Abbott Laboratories Removal of stratum corneum by means of light
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
US20030060718A1 (en) * 1999-09-10 2003-03-27 Akorn, Inc. Indocyanine green (ICG) compositions and related methods of use

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Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196979A (en) * 1976-10-16 1980-04-08 Canon Kabushiki Kaisha Method and device for detecting distance between eye-examining instrument and eye
JPS5843090B2 (en) * 1977-04-12 1983-09-24 キヤノン株式会社 Ophthalmological device with adjustment system
JPS53126792A (en) * 1977-04-12 1978-11-06 Canon Kk Ophthalmologic device having alignment system
US4252420A (en) * 1977-04-12 1981-02-24 Canon Kabushiki Kaisha Ophthalmoscopical apparatus provided with adjustment system
US4253743A (en) * 1977-05-17 1981-03-03 Canon Kabushiki Kaisha Eye testing instrument
US4277150A (en) * 1977-08-24 1981-07-07 Tokyo Kogaku Kikai Kabushiki Kaisha Eye refractmeter
US4180323A (en) * 1977-09-30 1979-12-25 American Optical Corporation Alignment system and ophthalmic instrument incorporating the same
JPS5542624A (en) * 1978-09-20 1980-03-26 Canon Kk Automatic eye refraction measuring system
JPS6153052B2 (en) * 1978-09-20 1986-11-15 Canon Kk
US4306778A (en) * 1978-11-13 1981-12-22 Tokyo Kogaku Kikai Kabushiki Kaisha Eye refractmeters using infrared rays
US4364646A (en) * 1979-03-13 1982-12-21 Nippon Kogaku K.K. Position adjusting device for ophthalmologic instrument
JPS6159134B2 (en) * 1979-10-26 1986-12-15 Canon Kk
JPS5554934A (en) * 1979-10-26 1980-04-22 Canon Kk Automatic ocular refraction meter
US4407572A (en) * 1980-06-12 1983-10-04 Humphrey Instruments, Inc. Keratometer
US4397182A (en) * 1981-03-31 1983-08-09 The Babcock & Wilcox Company Method of aligning a water level indicator having a remote and a local readout display
US4923297A (en) * 1986-06-23 1990-05-08 Eyedentify, Inc. Optical alignment system
EP0437504A1 (en) * 1988-10-04 1991-07-24 Allergan Humphery Range detector for eye instrument having interrogating beam.
EP0437504A4 (en) * 1988-10-04 1992-10-28 Allergan Humphery Range detector for eye instrument having interrogating beam
US5793468A (en) * 1991-10-11 1998-08-11 Metaphase Corporation Automated hand-held keratometer
US5585873A (en) * 1991-10-11 1996-12-17 Alcon Laboratories, Inc. Automated hand-held keratometer
US5450144A (en) * 1992-09-25 1995-09-12 Optiko Scientific Ltd. Ophthalmologic examination and/or treatment apparatus including illuminator and magnifier assembly
EP0589825A3 (en) * 1992-09-25 1995-02-22 Optiko Scient Ltd Ophthalmologic examination and/or treatment apparatus.
EP0589825A2 (en) * 1992-09-25 1994-03-30 OPTIKO SCIENTIFIC Ltd. Ophthalmologic examination and/or treatment apparatus
WO1998048691A1 (en) * 1997-04-25 1998-11-05 Matthew Colvard Method for observing the eye in minimal light
WO1999059485A1 (en) * 1998-05-18 1999-11-25 Abbott Laboratories Removal of stratum corneum by means of light
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