US3916892A - Phlebotomy needle system incorporating means to add anticoagulant and wash liquid - Google Patents
Phlebotomy needle system incorporating means to add anticoagulant and wash liquid Download PDFInfo
- Publication number
- US3916892A US3916892A US464835A US46483574A US3916892A US 3916892 A US3916892 A US 3916892A US 464835 A US464835 A US 464835A US 46483574 A US46483574 A US 46483574A US 3916892 A US3916892 A US 3916892A
- Authority
- US
- United States
- Prior art keywords
- blood
- cannula
- auxiliary
- hub
- anticoagulant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
- A61M1/3646—Expelling the residual body fluid after use, e.g. back to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/84—Drainage tubes; Aspiration tips
- A61M1/85—Drainage tubes; Aspiration tips with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S604/00—Surgery
- Y10S604/903—Medical container with material agitation means
Definitions
- ABSTRACT A phlebotomy needle system providing means to introduce anticoagulant into blood immediately after it is discharged from the needle cannula into a blood transfer tube and to coat the walls of the tube with a thin film of anticoagulant up until at least that point where the anticoagulant is thoroughly mixed through the blood. Means are also provided within the same system for backflowing a wash solution into the needle.
- the needle systems presently used in the pheresis procedure are hooked up with an array of fitments and tubulationssuch that there are various discontinuities on the walls of the internal blood passage between the point of the cannula of the needle and the junction of the passage with the admission point of an anticoagulant which is added to the blood. It is well known that many of the discontinuities in the surface of a passageway for whole blood which has not been treated with an anticoagulant tend to initiate a clotting reaction which, over a brief period of time, will build up a clot of sufficient size torestrict blood flow.
- Still another primary object of this invention is to provide a phlebotomy needle system with such fitments and tubulation which incorporate directly therein means to introduce a saline wash solution through said needle when blood is notbeing carried through the needle.
- the cannula is fitted at the discharge end with a tapered hub positioned to allow a short free length of the cannula to extend beyond the hub.
- the hub makes a removable liquid-tight friction fit with one end of a socket member which has a central chamber.
- a central channel and two auxiliary side channels extend through the other end of the hub into the central chamber.
- the central channel is sized to permit a blood-transfer tubing to be inserted therein and bonded to the socket.
- the two auxiliary side channels have tubings inserted in them and these tubings are in turn bonded to the socket member.
- an anticoagulant is introduced through the tubing in one of the auxiliary channels it is caused to flow through the annular fluid passage to be mixed with the blood immediately as it is discharged from the cannula and to form a film along the inner wall of the blood-transfer tubing.
- a saline wash solution may be introduced through the tubing in the other of the auxiliary channels to flow through the annular fluid passage and enter the discharge end of the cannula.
- FIG. 1 is a general view of the needle system of this invention showing the auxiliary tubings attached to a source of an anticoagulant and a source of a saline wash solution;
- FIG. 2 is a side elevatidnal view of one embodiment of a needle of the needle system of this invention illustrating the use of a stainless steel cannula;
- FIG. 3 is a cross section of the needle of FIG. 2 taken through plane 33 of FIG. 2;
- FIG. 4 is a cross section of another embodiment of a needle of the needle system of this invention illustrating the use of a flexible cannula having a rigid lancet;
- FIG. 5 is a longitudinal cross section of the socket member of this invention showing the hub of the needle in fully engaged position
- FIG. 6 is a longitudinal cross section of the socket member of FIG. 5 taken through plane 6 6 of FIG. 4;
- FIG. 7 is a top plan view of the socket member-without tubulations; and I FIG. 8 is a cross section of the socket member of FIG. 5 taken through plane 88 of FIG. 5.
- the phlebotomy needle of this invention is illustrated in FIG. 1 with its harness attached to a source of anticoagulant a source of saline solution and a blood reservoir in the form of a centrifuge rotor.
- the needle 10 is comprised of a cannula 11, a hub 12 and a gripping member 13 affixed to the hub.
- the needle is shown to be partially withdrawn from its aseptic cover 14 which is not part of this invention.
- Hub 12 is engaged with a socket member 16 to which the blood-transfer tubing 17, the. anticoagulant tubing 18 and saline solution tubing 19 are affixed. Hub 16 and tubings 17, 18 and 19 make up the harness generally indicated at 20.
- Anticoagulant tubing 18 is shown to be connected to an anticoagulant source 21, and saline solution tubing to a saline solution source 22.
- Pinch clamps 23 and 24 are provided to control the flow of the anticoagulant and saline solution, respectively.
- the liquids are gravity fed. It is, of course, within the scope of this invention to use any other means to cause the anticoagulant and the saline solutions to flow in their respective tubings and to use means other thanpinch clamps to control their flow. The actual means by which these liquids are introduced into and pumped through the tubulations is not part ofthis invention.
- the blood transfer tubing is shown to be connected to a reservoir 25, such as a centrifuge rotor of a system similar to that shown in US. Pat. No. 3,145,713.
- FIGS. 2-4 Two embodiments of needles suitable for use in the needle system of this invention are shown in side elevationaland crosssectional views in FIGS. 2-4.
- FIGS. 2-4 Two embodiments of needles suitable for use in the needle system of this invention are shown in side elevationaland crosssectional views in FIGS. 2-4.
- the same reference numerals are used to identify the same elements of the apparatus.
- the end 28 of the lancet which extends just beyond the inlet end of cannula 25 is configured to gain ready access to the interior of the vein and provide for the insertion of flexible cannula 25 into the vein, and the end 29 of the lancet which extends beyond the discharge end of cannula 25 is bonded to a needle cap 32 which is configured to fit over hub 12. Subsequent to making the venipuncture, cap 32 is removed while pressure is supplied to the vein, thus withdrawing the lancet and opening the passage in flexible cannula 25.
- the term cannula" is therefore hereinafter used in its broadest sense to designate either a rigid or flexible tubing member.
- the cannula 11 of FIGS. 2 and 3 is shown as an exemplary cannula.
- the hub 12 typically formed of a haemocompatible molded plastic such as polycarbonate, is fitted onto the discharge end of the cannula and bonded thereto by ultrasonic insertion or by a suitable adhesive.
- Hub 12 has a tapered section 30, the diameter decreasing toward the discharge end of cannula l1, and a straight section 31.
- the gripping member 13 (or 13a in FIG. 4) is attached to straight section 31.
- a short length of cannula 11 or 25 extends beyond the tapered section of the hub.
- gripping member 13 or 13a is of a flat configuration designed to give the doctor or nurse performing the venipuncture a firm grip on the needle and a means for sensing needle orientation.
- the socket member 16 through which the needle is removably attached to the harness, is shown in several views in FIGS. 5 8.
- This socket like the hub 12 is molded of a suitable haemocompatible synthetic resin material such as a polycarbonate. Socket 16 is formed to have a needle-engaging section 35, shown in the drawings to have an external taper with the diameter increasing toward the discharge end of cannula l1, and a tubulation-engaging section 36 of a generally elliptical configuration-as seen in FIGS. 7 and 8.
- Needle-engaging section 35 has a hub-engaging passage 37 having a tapered configuration, the diameter of the internal walls of the passage decreasing toward the internal opening 38 which terminates in central chamber 39 within the socket member.
- the degree of taper of passage 37 corresponds to that of hub section 30 so that when the needle is affixed to the socket, the surface of hub section 30 makes a liquidtight friction fit with the wall of hub-engaging-passage 37 of the socket member.
- Tubulation section 36 of the socket member (shown in top plan-view of FIG. 7 and in cross-section in FIG. 8) is configured to accept and hold blood-transfer tubing 17 axially aligned with cannula 11 and'the two auxiliary tubings 18 and .19 for anticoagulant and saline solution on either side.
- a central channel 40 defined by wall 41 which terminates internally in the socket in a lip 42, serves to receive and holdblood-transfer tubing 17.
- This tubing is seated on lip 42 and is bonded to the socket member such as by solvent bonding around en- 1, trance 43 of channel 40.
- the location of the lip seat '42 should be such as to position blood-transfer tubing 17 so that the free end of cannula 11 extends into it to define an annular liquid passageway 44.
- the socket member has a wall 45, merging into one side of wall 41, to define channel 46'terminating in a lip 47 to receive and seat anticoagulant tubing 18 which is bonded at 48 to the socket. Liquid communication between tubing 18 and central chamber 39 is by way of channel 49.
- the socket member has a wall 50, merging into the other side of wall 41, to define channel 51 terminating in a lip 52 to receive and seat saline solution tubing 19 whichis bonded at 53 to the socket. Liquid communication between tubing 19 and central chamber 39 is by way of channel 54.
- the anticoagulant is available for mixing with 'the blood (the flow of which is indicated by the solid arrows?) immediately upon its discharge from cannula IL
- This flow pattern of the anticoagulant which is, of course, around the entire surface of cannula 1.1, also provides a continuous film of anticoagulant aroundthe entire surface of the inner wall of tubulation l7 up to at least a point where the anticoagulant is thoroughly mixed with the blood. This means that the unanticoagulated blood never comes into contact with any discontinuities in the transfer system which could give rise .to clotting. Hence a free flow of blood is insured throughout the pheresis procedure. l
- the flow of saline wash solution is begun supporting means within said socket member by which th e inlet end of said blood transfer tubeissupported in position-to surround said discharge end of said cannula to define an annular passage therebetweenproviding communicationbetween said centralchamber and said blood transfer tube, afirst auxiliarytransfer tube, and means by which thedischarge end of said first auxiliary means by which the discharge end of said second auxilcommunication with said annular passage dle without the need for replacing the socket and the tubulation connections as well.
- a phlebotomy needle system suitable for with drawing blood from a donor and delivering said blood to a reservoir through a blood transfer tube, including a needle cannula and hub affixed thereto and having tubulation means for introducing an anticoagulant into said blood as it is transferred to said reservoir, the improvement comprising a socket member removably 6 iary transfer tube is supported in said socket member whereby said second auxiliary transfer tube is in fluid through said central chamber.
- a phlebotomy needle system including a needle cannula suitable for withdrawing blood from a donor and having tubulation means for introducing an-anticoagulant into said blood as it is transferred to a reservoir, the improvement comprising a. a tapered hub fit over the discharge end of said cannula of said needle to allow a short length of said discharge end to extend beyond said hub; and
- a first side channel having affixed therein a first auxiliary tubing in fluid communication through said central chamber with said annular fluid passage, whereby when an anticoagulant is introduced through said first auxiliary tubing it is mixed with said blood before it encounters any surface beyond said discharge end of said cannula.
- a phlebotomy needle system particularly suited for use in a pheresis procedure, comprising in combination a. a needle comprising a cannula and a hub which includes a tapered section, and is affixed to said cannula to allow a short free length of the discharge end of said cannula to extend beyond said hub;
- a primary tubing adapted to transfer blood and two auxiliary tubings adapted to transfer an anticoagulant and a wash solution;
- a socket member removably engaged with said hub, having a central chamber and holding the ends of said primary and auxiliary tubings in relation to the discharge end of said cannula whereby said free length of said cannula-extends through said central chamber into said primary tubing to define an annular passage providing fluid communication between said central chamber and said primary tubing and said auxiliary tubings are in fluid communication with said annular path through said central chamber.
- a phlebotomy needle system in accordance with claim 5 including gripper means affixed to said hub.
- a phlebotomy needle system in accordance with claim 5 including a source of an anticoagulant connected to one of said auxiliary tubings and a saline wash solution connected to the other of said auxiliary tubings and means to-control the flow of said anticoagulant and said wash solution through said tubings.
Abstract
Description
Claims (15)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US464835A US3916892A (en) | 1974-04-29 | 1974-04-29 | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
CA223,450A CA1056682A (en) | 1974-04-29 | 1975-04-01 | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
DE19752517311 DE2517311A1 (en) | 1974-04-29 | 1975-04-18 | PHLEBOTOMY NEEDLE SYSTEM |
JP50049857A JPS50149174A (en) | 1974-04-29 | 1975-04-25 | |
GB17615/75A GB1490165A (en) | 1974-04-29 | 1975-04-28 | Phlebotomy needle arrangements |
IT68083/75A IT1032772B (en) | 1974-04-29 | 1975-04-28 | PHLEBOTOMIC NEEDLE DEVICE FOR BLOOD COLLECTION |
FR7513219A FR2268537A1 (en) | 1974-04-29 | 1975-04-28 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US464835A US3916892A (en) | 1974-04-29 | 1974-04-29 | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
Publications (1)
Publication Number | Publication Date |
---|---|
US3916892A true US3916892A (en) | 1975-11-04 |
Family
ID=23845432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US464835A Expired - Lifetime US3916892A (en) | 1974-04-29 | 1974-04-29 | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
Country Status (7)
Country | Link |
---|---|
US (1) | US3916892A (en) |
JP (1) | JPS50149174A (en) |
CA (1) | CA1056682A (en) |
DE (1) | DE2517311A1 (en) |
FR (1) | FR2268537A1 (en) |
GB (1) | GB1490165A (en) |
IT (1) | IT1032772B (en) |
Cited By (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4086924A (en) * | 1976-10-06 | 1978-05-02 | Haemonetics Corporation | Plasmapheresis apparatus |
US4280496A (en) * | 1979-02-16 | 1981-07-28 | Baxter Travenol Laboratories, Inc. | Phlebotomy needle assembly |
US4585435A (en) * | 1984-05-31 | 1986-04-29 | The Telescope Folding Furniture Co., Inc. | Extension set for drug delivery |
US4601697A (en) * | 1982-10-29 | 1986-07-22 | Miles Laboratories, Inc. | Long indwelling double bore catheter |
WO1986004818A1 (en) * | 1985-02-26 | 1986-08-28 | Baxter Travenol Laboratories, Inc. | Fluid transfer system |
US4713057A (en) * | 1984-02-27 | 1987-12-15 | Medical College Of Ohio | Mechanical assist device for inserting catheters |
US4855064A (en) * | 1988-01-13 | 1989-08-08 | Viratec, Inc. | Apparatus and method for decontaminating virus-infected body fluids |
US4892518A (en) * | 1987-12-04 | 1990-01-09 | Biocontrol Technology, Inc. | Hemodialysis |
US4929242A (en) * | 1986-11-26 | 1990-05-29 | Baxter International Inc. | Solution and method for maintaining patency of a catheter |
US4954129A (en) * | 1988-07-25 | 1990-09-04 | Abbott Laboratories | Hydrodynamic clot flushing |
US5009634A (en) * | 1989-01-11 | 1991-04-23 | The University Of Virginia Alumni Patents Foundation | Metabolic catheter |
US5049393A (en) * | 1986-01-07 | 1991-09-17 | Baylor College Of Medicine | Anti-thrombogenic elastomer and objects and prostheses made therefrom |
WO1992011891A1 (en) * | 1990-12-28 | 1992-07-23 | Abbott Laboratories | Patency maintenance system |
US5195967A (en) * | 1992-02-18 | 1993-03-23 | Nakao Naomi L | Anticlotting device and method for use with IV catheters |
US5295953A (en) * | 1992-05-26 | 1994-03-22 | Hemagen/Pfc | Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient |
US5312361A (en) * | 1991-09-13 | 1994-05-17 | Zadini Filiberto P | Automatic cannulation device |
US5421812A (en) * | 1992-03-04 | 1995-06-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in tubing system |
US5639382A (en) * | 1991-12-23 | 1997-06-17 | Baxter International Inc. | Systems and methods for deriving recommended storage parameters for collected blood components |
US5676841A (en) * | 1991-12-23 | 1997-10-14 | Baxter International Inc. | Blood processing systems and methods which monitor citrate return to the donor |
US5676645A (en) * | 1992-03-04 | 1997-10-14 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems |
US5681273A (en) * | 1991-12-23 | 1997-10-28 | Baxter International Inc. | Systems and methods for predicting blood processing parameters |
US5690835A (en) * | 1991-12-23 | 1997-11-25 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
US5730883A (en) * | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US5759413A (en) * | 1995-06-07 | 1998-06-02 | Baxter International Inc. | Systems and method for estimating platelet counts using a spleen mobilization function |
US5762791A (en) * | 1995-08-09 | 1998-06-09 | Baxter International Inc. | Systems for separating high hematocrit red blood cell concentrations |
US5817042A (en) * | 1992-03-04 | 1998-10-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in vivos and in tubing systems |
US5833866A (en) * | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing |
US6007725A (en) * | 1991-12-23 | 1999-12-28 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
US6251284B1 (en) | 1995-08-09 | 2001-06-26 | Baxter International Inc. | Systems and methods which obtain a uniform targeted volume of concentrated red blood cells in diverse donor populations |
US20030018357A1 (en) * | 2001-05-09 | 2003-01-23 | Luthra Ajay K. | Wound closure system and methods |
US6527957B1 (en) | 1995-08-09 | 2003-03-04 | Baxter International Inc. | Methods for separating, collecting and storing red blood cells |
US20040186414A1 (en) * | 2003-02-03 | 2004-09-23 | Maurice Behague | Collection bag system with preformed loop |
WO2007049092A1 (en) * | 2005-10-27 | 2007-05-03 | Gambro Lundia Ab | Extracorporeal blood set |
US20080167577A1 (en) * | 2006-12-29 | 2008-07-10 | Weilbacher Eugene E | Vented phlebotomy needle with flashback chamber |
US20090088617A1 (en) * | 2007-09-27 | 2009-04-02 | Tyco Healthcare Group Lp | Phlebotomy Needle with Shape Memory Alloy Flashback Sensor |
US20100168643A1 (en) * | 2007-09-05 | 2010-07-01 | Gambro Lundia Ab | Infusion site for improved mixing of fluids |
US8986238B2 (en) | 2012-08-15 | 2015-03-24 | Cyclone Medtech, Inc. | Systems and methods for salvaging red blood cells for autotransfusion |
WO2015179329A1 (en) * | 2014-05-19 | 2015-11-26 | Walk Vascular, Llc | Systems and methods for removal of blood and thrombotic material |
US9248221B2 (en) | 2014-04-08 | 2016-02-02 | Incuvate, Llc | Aspiration monitoring system and method |
US9433427B2 (en) | 2014-04-08 | 2016-09-06 | Incuvate, Llc | Systems and methods for management of thrombosis |
CN107475094A (en) * | 2017-08-11 | 2017-12-15 | 河南科技大学第附属医院 | A kind of haemocyte separating pipe and separation method |
US10226263B2 (en) | 2015-12-23 | 2019-03-12 | Incuvate, Llc | Aspiration monitoring system and method |
US10561440B2 (en) | 2015-09-03 | 2020-02-18 | Vesatek, Llc | Systems and methods for manipulating medical devices |
US10702292B2 (en) | 2015-08-28 | 2020-07-07 | Incuvate, Llc | Aspiration monitoring system and method |
US11497521B2 (en) | 2008-10-13 | 2022-11-15 | Walk Vascular, Llc | Assisted aspiration catheter system |
US11510689B2 (en) | 2016-04-06 | 2022-11-29 | Walk Vascular, Llc | Systems and methods for thrombolysis and delivery of an agent |
US11540847B2 (en) | 2015-10-09 | 2023-01-03 | Incuvate, Llc | Systems and methods for management of thrombosis |
US11653945B2 (en) | 2007-02-05 | 2023-05-23 | Walk Vascular, Llc | Thrombectomy apparatus and method |
US11678905B2 (en) | 2018-07-19 | 2023-06-20 | Walk Vascular, Llc | Systems and methods for removal of blood and thrombotic material |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4110454B2 (en) * | 2002-05-17 | 2008-07-02 | 日立工機株式会社 | Cell washing centrifuge |
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US2638897A (en) * | 1951-01-18 | 1953-05-19 | Edward J Poitras | Flared exit phlebotomy needle |
US2804075A (en) * | 1955-11-14 | 1957-08-27 | Ruth O Borden | Non-clogging surgical aspirator |
US3217711A (en) * | 1963-08-01 | 1965-11-16 | Abbott Lab | Valve apparatus for sequentially administering parenteral fluid from separate sources |
US3610226A (en) * | 1968-02-27 | 1971-10-05 | Anthony M Albisser | A double lumen cannula for blood sampling |
US3675891A (en) * | 1970-09-18 | 1972-07-11 | Voys Inc Le | Continuous catheter flushing apparatus |
-
1974
- 1974-04-29 US US464835A patent/US3916892A/en not_active Expired - Lifetime
-
1975
- 1975-04-01 CA CA223,450A patent/CA1056682A/en not_active Expired
- 1975-04-18 DE DE19752517311 patent/DE2517311A1/en not_active Withdrawn
- 1975-04-25 JP JP50049857A patent/JPS50149174A/ja active Pending
- 1975-04-28 GB GB17615/75A patent/GB1490165A/en not_active Expired
- 1975-04-28 IT IT68083/75A patent/IT1032772B/en active
- 1975-04-28 FR FR7513219A patent/FR2268537A1/fr not_active Withdrawn
Patent Citations (5)
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US2638897A (en) * | 1951-01-18 | 1953-05-19 | Edward J Poitras | Flared exit phlebotomy needle |
US2804075A (en) * | 1955-11-14 | 1957-08-27 | Ruth O Borden | Non-clogging surgical aspirator |
US3217711A (en) * | 1963-08-01 | 1965-11-16 | Abbott Lab | Valve apparatus for sequentially administering parenteral fluid from separate sources |
US3610226A (en) * | 1968-02-27 | 1971-10-05 | Anthony M Albisser | A double lumen cannula for blood sampling |
US3675891A (en) * | 1970-09-18 | 1972-07-11 | Voys Inc Le | Continuous catheter flushing apparatus |
Cited By (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2392663A1 (en) * | 1976-10-06 | 1978-12-29 | Haemonetics Corp | |
US4086924A (en) * | 1976-10-06 | 1978-05-02 | Haemonetics Corporation | Plasmapheresis apparatus |
US4280496A (en) * | 1979-02-16 | 1981-07-28 | Baxter Travenol Laboratories, Inc. | Phlebotomy needle assembly |
US4601697A (en) * | 1982-10-29 | 1986-07-22 | Miles Laboratories, Inc. | Long indwelling double bore catheter |
US4713057A (en) * | 1984-02-27 | 1987-12-15 | Medical College Of Ohio | Mechanical assist device for inserting catheters |
US4585435A (en) * | 1984-05-31 | 1986-04-29 | The Telescope Folding Furniture Co., Inc. | Extension set for drug delivery |
WO1986004818A1 (en) * | 1985-02-26 | 1986-08-28 | Baxter Travenol Laboratories, Inc. | Fluid transfer system |
US4786286A (en) * | 1985-02-26 | 1988-11-22 | Baxter Travenol Laboratories, Inc. | Fluid transfer system |
US5049393A (en) * | 1986-01-07 | 1991-09-17 | Baylor College Of Medicine | Anti-thrombogenic elastomer and objects and prostheses made therefrom |
US4929242A (en) * | 1986-11-26 | 1990-05-29 | Baxter International Inc. | Solution and method for maintaining patency of a catheter |
US4892518A (en) * | 1987-12-04 | 1990-01-09 | Biocontrol Technology, Inc. | Hemodialysis |
US4855064A (en) * | 1988-01-13 | 1989-08-08 | Viratec, Inc. | Apparatus and method for decontaminating virus-infected body fluids |
US4954129A (en) * | 1988-07-25 | 1990-09-04 | Abbott Laboratories | Hydrodynamic clot flushing |
US5009634A (en) * | 1989-01-11 | 1991-04-23 | The University Of Virginia Alumni Patents Foundation | Metabolic catheter |
WO1992011891A1 (en) * | 1990-12-28 | 1992-07-23 | Abbott Laboratories | Patency maintenance system |
US5205818A (en) * | 1990-12-28 | 1993-04-27 | Abbott Laboratories | Patency maintenance system |
US5312361A (en) * | 1991-09-13 | 1994-05-17 | Zadini Filiberto P | Automatic cannulation device |
US5833866A (en) * | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing |
US5730883A (en) * | 1991-12-23 | 1998-03-24 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US6207063B1 (en) | 1991-12-23 | 2001-03-27 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US6059979A (en) * | 1991-12-23 | 2000-05-09 | Baxter International Inc. | Blood processing systems and methods using apparent hematocrit as a process control parameter |
US5639382A (en) * | 1991-12-23 | 1997-06-17 | Baxter International Inc. | Systems and methods for deriving recommended storage parameters for collected blood components |
US5676841A (en) * | 1991-12-23 | 1997-10-14 | Baxter International Inc. | Blood processing systems and methods which monitor citrate return to the donor |
US6007725A (en) * | 1991-12-23 | 1999-12-28 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
US5681273A (en) * | 1991-12-23 | 1997-10-28 | Baxter International Inc. | Systems and methods for predicting blood processing parameters |
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Also Published As
Publication number | Publication date |
---|---|
CA1056682A (en) | 1979-06-19 |
IT1032772B (en) | 1979-06-20 |
JPS50149174A (en) | 1975-11-29 |
DE2517311A1 (en) | 1975-11-06 |
GB1490165A (en) | 1977-10-26 |
FR2268537A1 (en) | 1975-11-21 |
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