|Numéro de publication||US4170227 A|
|Type de publication||Octroi|
|Numéro de demande||US 05/917,877|
|Date de publication||9 oct. 1979|
|Date de dépôt||22 juin 1978|
|Date de priorité||27 déc. 1976|
|Numéro de publication||05917877, 917877, US 4170227 A, US 4170227A, US-A-4170227, US4170227 A, US4170227A|
|Inventeurs||Charles L. Feldman, Mark Hubelbank|
|Cessionnaire d'origine||Electronics For Medicine, Inc.|
|Exporter la citation||BiBTeX, EndNote, RefMan|
|Citations de brevets (6), Référencé par (42), Classifications (9), Événements juridiques (1)|
|Liens externes: USPTO, Cession USPTO, Espacenet|
This is a continuation-in-part of application Ser. No. 754,538, filed Dec. 27, 1976 now U.S. Pat. No. 4112,930.
The present invention relates in general to detecting the shift in the baseline in an electrocardiogram (ECG) and more particularly concerns a novel system using a multiple element electrode at a single measuring location with means for detecting potential differences between elements to reliably detect the occurrence of a baseline shift, thereby preventing automatic monitoring equipment from indicating an alarm condition about a patient being monitored when an alarm condition should not be indicated. The apparatus is relatively easy to fabricate and install, adds relatively little cost to the system and operates relatively reliably with little attention from maintenance personnel.
Automatic ECG monitoring systems, whether using simple rate alarms on a bedside monitor or more complex arrhythmia detectors, produce erroneous results at times because of the presence of a non-ECG artifact, consisting of a combination of high frequency "muscle noise" and lower frequency "baseline shift". The present invention is concerned with detecting baseline shift; that is, a shift in the average value of the ECG signal over a waveform portion.
The usual cause of "baseline shift" is physical manipulation of the electrodes or the skin and muscle underlying electrodes which may result from movement of an electrode, pressing of the surfaces as a result of patient movement, tugging upon the electrode lead and other causes. Good preparation of the skin surface to which the electrode is attached helps minimize baseline shift but does not eliminate it. As an example of one approach to dealing with this problem reference is made to U.S. Pat. No. 3,905,364 entitled ARTIFACT DETECTOR.
The prior art includes a number of patents on electrodes and multiple electrode systems. In the prior art multiple electrode systems, multiple electrodes or multielement electrodes are used to derive better estimates of the signal or to provide flexibility. Some multiple electrode systems are used to achieve rapid applications in emergency situations.
Prior art artifact detecting systems exemplified by Cudahy U.S. Pat. No. 3,905,364, Horth U.S. Pat. No. 3,552,386 and Vandenberg U.S. Pat. No. 3,050,841 detect artifact signals by sensing changes in the received signal out of range of a predetermined expected normal ECG from the same pair of electrodes used to derive the desired ECG signal; that is, between an electrode at a first ground or common location and an electrode at an ungrounded or uncommon location.
Holsinger U.S. Pat. No. 3,868,947 describes a multiple electrode system for artifact compensation and assumes a common mode artifact signal on the center electrodes of spaced coaxial electrode pairs in contact with the skin at spaced points with the outer annular electrode of each pair connected together and to a common ground of a differential amplifier having a pair of inputs respectively connected to respective ones of the center electrodes in a pair. This approach is of limited utility in solving the problem of detecting baseline shift because the causes of basline shift at the location of one pair of electrodes is not likely to produce the same baseline shift, if any, at a spaced pair of electrodes.
Accordingly, it is an important object of this invention to provide improved methods and means for detecting baseline shift in an ECG signal.
It is a further object of the invention to achieve the preceding object with apparatus that is relatively easy and inexpensive to fabricate and install while providing a relatively reliable indication of baseline shift with relatively little attention to the apparatus.
It is a further object of the invention to achieve one or more of the preceding objects while providing a useful signal.
It is a further object of the invention to achieve one or more of the preceding objects useful in automatic ECG monitoring systems helpful in avoiding erroneous alarm conditions.
According to the invention, there are first and second multielement electrode means attached to first and second surface portions of a patient, each electrode means having elements closely spaced but insulatedly separated, the ECG potential between the elements being negligible, there are first and second means for differentially combining, respectively, the potentials of one element from each of the multielement electrode means, and the potentials of the other element from each of the multielement electrode means, to provide first and second ECG signals, and means for differentially combining the ECG signals to provide an artifact signal representative of baseline shift.
Preferably, the first and second multielement electrode means are spaced by a distance greater than that between the elements of each of the electrode means, the distance between the elements is less than one inch, there are means for combining the ECG signals, and there is a third electrode means at a third patient surface portion, the differential combining means having a common input connected to it.
The method of the invention comprises positioning such multielement electrode portions on first and second patient surface portions, combining differentially the ECG potential of first elements from each multielement electrode and second the other elements from the multielement electrodes, to provide first and second ECG signals, and then differentially combining the two ECG signals to provide an artifact signal. Numerous other features, objects and advantages will become apparent from the following specifications when read in connection with the accompanying drawing in which:
FIG. 1 is a graphical representation of an ECG signal indicating the occurrence of baseline·shift; and
FIG. 2 is a combined block-diagram pictorial representation of an exemplary embodiment of a system according to the invention.
With reference now to the drawing and more particularly FIG. 1 thereof, there is shown a graphical representation of an ECG signal with baseline shift occurring in the interval of the third illustrated beat 11 where the baseline shifts below the normal baseline level 12.
Referring to FIG. 2, there is shown a combined block pictorial representation of a system according to the invention for detecting baseline shift. The system includes a first ground, common or reference electrode 13 at a first surface location of patient 14 being monitored, a first pair of elements 15 and 16 of a multielement electrode at a second surface location of patient 14 and a second pair of elements 17 and 18 of another multielement electrode at a third surface location of patient 14. The spacing between elements 15 and 16 and between elements 17 and 18 is significantly less than the separation between the first location and each of the second and third locations and preferably that between the second and third locations. Typical separations between elements 17 and 18 and between elements 15 and 16 is one inch or less, and they are preferably arranged so that a line connecting their centers is perpendicular to the electrical axis of the heart. The separation between elements in a multielement electrode is small enough so that the ECG potential between them is negligible and large enough so that the motion of one electrode is at least partially independent of the motion of the other. The pairs of elements may be concentric as shown in Holsinger U.S. Pat. No. 3,868,947; however, the connections to external amplifying apparatus is different and as described below.
The systems includes a first.ECG differential amplifier 21 for providing a first ECG signal on line 22, and a second ECG differential amplifier 23 for providing a second ECG signal on line 24. It also includes a differential combiner 25, which need not be an amplifier, for providing an artifact signal on line 26. Differential combiner 25 receives the signals on lines 22 and 24. ECG utilizing means 27 receives the signals on lines 22, 24 and 26 and typically provides an alarm signal only when the ECG signal characterizes an unstable condition of patient 14, such as arrhythmia or an unacceptable heartbeat rate, while preventing the occurrence of an alarm signal when an artifact signal on line 26 occurs, signifying that a condition has occurred at an associated pair of elements producing a baseline shift.
The grounded, common or reference input C of each differential amplifier 21 and 23 is connected to reference electrode 13 at the first patient surface location. It is common practice to have a reference terminal such as 13 attached to the patient and connected to one or more common terminals of the amplifying means for reducing noise. The 1 and 2 signal inputs of first ECG differential amplifier 21 are connected to electrode elements 17 and 15, respectively, the elements being selected from different multielement electrodes at different patient locations. The 1 and 2 signal inputs of the second ECG differential amplifier 23 are connected to the other elements 18 and 16, respectively, of the different multielement electrodes.
Accordingly, two nearly identical ECG signals 22 and 24 from two multielement electrodes are produced. The difference between these two parallel ECG signals, as detected by differential combiner 25, is baseline shift, creating artifact signal 26.
The specific means for utilizing the ECG signals 22 and 24 and the artifact signal 26 is not a part of the invention. For example, it is possible to use either of the ECG signals 22 and 24 or to combine the two by summation to produce the true ECG. Or ECG utilizing means 27 may include, in addition, circuitry that responds to the occurrence of an artifact signal on line 26 for providing a signal that inhibits the alarm indicating circuitry. The ECG utilizing means might also or alternatively include circuitry for combining the artifact signal with the ECG signal to effectively restore the shifted baseline substantially to the normal baseline 12.
There has been described novel apparatus and techniques for detecting a baseline shift in an ECG signal. It is evident that those skilled in the art may now make numerous modifications and uses of and departures from the specific embodiment described herein without departing from the inventive concepts. Consequently, the invention is to be construed as embracing each and every novel feature and novel combination of features present in or possessed by the apparatus and techniques herein disclosed and limited solely by the spirit and scope of the appended claims.
|Brevet cité||Date de dépôt||Date de publication||Déposant||Titre|
|US3212496 *||21 août 1962||19 oct. 1965||United Aircraft Corp||Molecular physiological monitoring system|
|US3559193 *||20 nov. 1967||26 janv. 1971||Beckman Instruments Inc||Common mode signal detection|
|US3608543 *||3 oct. 1968||28 sept. 1971||Univ Carnegie Mellon||Physiological impedance-measuring apparatus|
|US3699948 *||14 mai 1971||24 oct. 1972||Jeol Ltd||Recording device with automatic gain range changer and d.c. correction means|
|US3868947 *||16 oct. 1973||4 mars 1975||Us Government||Concentric electrode construction for an electrocardiogram transmitter|
|US3903874 *||27 août 1973||9 sept. 1975||Mediscience Technology Corp||Cardiographic signal processing means and method|
|Brevet citant||Date de dépôt||Date de publication||Déposant||Titre|
|US4537200 *||7 juil. 1983||27 août 1985||The Board Of Trustees Of The Leland Stanford Junior University||ECG enhancement by adaptive cancellation of electrosurgical interference|
|US4583553 *||15 nov. 1983||22 avr. 1986||Medicomp, Inc.||Ambulatory ECG analyzer and recorder|
|US5127401 *||9 nov. 1990||7 juil. 1992||Medtronic, Inc.||Method of and apparatus for multi-vector pacing artifact detection|
|US5269313 *||9 sept. 1991||14 déc. 1993||Sherwood Medical Company||Filter and method for filtering baseline wander|
|US5560369 *||22 sept. 1994||1 oct. 1996||Pacesetter, Inc.||Cardiac arrhythmia detection system for an implantable stimulation device and method|
|US6032072 *||30 janv. 1998||29 févr. 2000||Aspect Medical Systems, Inc.||Method for enhancing and separating biopotential signals|
|US6496715||22 nov. 2000||17 déc. 2002||Medtronic, Inc.||System and method for non-invasive determination of optimal orientation of an implantable sensing device|
|US6505067||22 nov. 2000||7 janv. 2003||Medtronic, Inc.||System and method for deriving a virtual ECG or EGM signal|
|US6512940||31 oct. 2000||28 janv. 2003||Medtronic, Inc.||Subcutaneous spiral electrode for sensing electrical signals of the heart|
|US6522915||26 oct. 2000||18 févr. 2003||Medtronic, Inc.||Surround shroud connector and electrode housings for a subcutaneous electrode array and leadless ECGS|
|US6564106||13 déc. 2000||13 mai 2003||Medtronic, Inc.||Thin film electrodes for sensing cardiac depolarization signals|
|US6584352||27 déc. 2000||24 juin 2003||Medtronic, Inc.||Leadless fully automatic pacemaker follow-up|
|US6622046||7 mai 2001||16 sept. 2003||Medtronic, Inc.||Subcutaneous sensing feedthrough/electrode assembly|
|US6631290||25 oct. 2000||7 oct. 2003||Medtronic, Inc.||Multilayer ceramic electrodes for sensing cardiac depolarization signals|
|US6728576||31 oct. 2001||27 avr. 2004||Medtronic, Inc.||Non-contact EKG|
|US7471977 *||30 juin 2004||30 déc. 2008||General Electric Company||Method and system for detecting pace pulses|
|US7835793||31 janv. 2007||16 nov. 2010||Medtronic, Inc.||Insert molded shroud for implantable plate-type electrodes|
|US7881765||1 févr. 2011||Medtronic, Inc.||Interference-fit shroud-based cardiac electrodes|
|US7925322||28 avr. 2006||12 avr. 2011||Medtronic, Inc.||Shroud-based electrodes having vented gaps|
|US8750991||19 avr. 2012||10 juin 2014||Zoll Medical Corporation||Monitoring physiological signals during external electrical stimulation|
|US9000931||30 mai 2012||7 avr. 2015||Fujitsu Limited||Noise processing apparatus|
|US9289178 *||19 juil. 2011||22 mars 2016||Samsung Electronics Co., Ltd.||Apparatus, unit measurer and method of measuring biological signal|
|US9381366||16 mars 2007||5 juil. 2016||Medtronic, Inc.||Methods and apparatus for improved IPG rate response using subcutaneous electrodes directly coupled to an implantable medical device (IMD)|
|US20060020219 *||30 juin 2004||26 janv. 2006||Zinser Richard L Jr||Method and system for detecting pace pulses|
|US20070255156 *||28 avr. 2006||1 nov. 2007||Mertz John C||Interference-fit shroud-based cardiac electrodes|
|US20070255157 *||28 avr. 2006||1 nov. 2007||Stancer Christopher C||Drug eluting shroud-based electrodes|
|US20070255158 *||28 avr. 2006||1 nov. 2007||Stancer Christopher C||Shroud-based electrodes having vented gaps|
|US20080183089 *||31 janv. 2007||31 juil. 2008||Greeninger Daniel R||Tissue ingrowth enhancement for shroud-based plate electrodes configured for chronic implantation|
|US20080183225 *||31 janv. 2007||31 juil. 2008||Adamski Thomas H||Orientation-independent implantable electrode arrays|
|US20080183233 *||31 janv. 2007||31 juil. 2008||Koch Alexandra M||Insert molded shroud for implantable plate-type electrodes|
|US20080183235 *||31 janv. 2007||31 juil. 2008||Stancer Christopher C||Insulative shroud for plate-type electrodes adapted for chronic implantation|
|US20080228234 *||16 mars 2007||18 sept. 2008||Stancer Christopher C||Methods and apparatus for improved ipg rate response using subcutaneous electrodes directly coupled to an implantable medical device (imd)|
|US20080234591 *||20 mars 2007||25 sept. 2008||Scinicariello Anthony P||Methods and apparatus for patient notification of physiologic events and device function|
|US20120232369 *||13 sept. 2012||Samsung Electronics Co., Ltd.||Apparatus, unit measurer and method of measuring biological signal|
|EP0113854A1 *||7 déc. 1983||25 juil. 1984||Siemens Aktiengesellschaft||Bifocal pacemaker with two unipolar electrodes|
|EP2508125A1 *||30 nov. 2009||10 oct. 2012||Fujitsu Limited||Noise processing device and noise processing program|
|EP2508125A4 *||30 nov. 2009||2 oct. 2013||Fujitsu Ltd||Noise processing device and noise processing program|
|WO1999038437A1||25 janv. 1999||5 août 1999||Aspect Medical Systems, Inc.||System and method for enhancing and separating biopotential signals|
|WO2002034332A1||5 oct. 2001||2 mai 2002||Medtronic, Inc.||Multilayer ceramic electrodes for sensing cardiac depolarization signals|
|WO2002034333A2||5 oct. 2001||2 mai 2002||Medtronic, Inc.||Surround shroud connector and electrode housings for a subcutaneous electrode array and leadless ecgs|
|WO2002036000A1||5 oct. 2001||10 mai 2002||Medtronic, Inc.||Subcutaneous spiral electrode for sensing electrical signals of the heart|
|WO2002098507A2||20 mars 2002||12 déc. 2002||Medtronic, Inc.||Implantable medical device with dual cell power source|
|Classification aux États-Unis||600/517|
|Classification internationale||A61B5/0408, A61B5/04|
|Classification coopérative||A61B5/04085, A61B5/7214, A61B5/04004|
|Classification européenne||A61B5/72B2D, A61B5/04J, A61B5/0408D|
|14 mai 1990||AS||Assignment|
Owner name: PPG INDUSTRIES, INC., PENNSYLVANIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:HONEYWELL INC.;REEL/FRAME:005385/0135
Effective date: 19861008