US462990A - William oppenheimek - Google Patents

William oppenheimek Download PDF

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US462990A
US462990A US462990DA US462990A US 462990 A US462990 A US 462990A US 462990D A US462990D A US 462990DA US 462990 A US462990 A US 462990A
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william
oppenheimek
soluble
casing
partition
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds

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  • GAPSULE i No. 462,990. Patented Nov. 10, 18911..
  • VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE.
  • My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain ⁇ the-different kinds of Inedieine.
  • FIG. 1 is a transverse sectional view 0f a capsuleeinbodying my invention.
  • Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.
  • the capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine.
  • the Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines.
  • the inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.
  • I claim- A capsuleconsisting; ⁇ of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.

Description

(No Model.)
W. OPPENHEIMER.
GAPSULE. i No. 462,990. Patented Nov. 10, 18911..
fy/ @2 193.- @f4 j l j j i@ @f @1% Y 3 l j s @d je'g Jyf z '1 .e j o., f o
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yi 71 W j@ za'ge jfzyj 1 j j j UNITED STATES PATENT OFFICE.
VILLIAM OPPENI-IEIMER, OF LONDON, ENGLAND- CAPSULE.
SPECIFICATION forming part'of Letters Patent No. 462,990, dated November 10, 1891..
Application filed September 23, 1891l Serial No. 398,711. (No specimens.) Patented in England January 29, 1891, No.1,651.
To L ZZ whom it may concern.-
Be it known that I, WILLIAM OPPENIIEIMEE, manufacturing chemist, a subject of the Queen of Great Britain, residing at 1 and 3 Sun Street and 39 XVilsonStreet, Finsbury Square, London, England, have invented a certain new and useful Improvement in Capsules and in the preparation of the same for use, (for which I have applied for a patent in Great Britain, No. 1,651, bearing,` date January 29, 1891,) of which the followingr is a specification.
My invention relates' to those forms of medicine which are conveyed into the system intact and are only intended todissolve and intermix after being taken into the stomach or elsewhere, where they are intended to operate; and the object of my i11- vention is to improve and extend the use of such preparations by manufacturing them in the form of capsules, each having a partition dividing it into a series of chambers which contain `the-different kinds of Inedieine.
The invention is illustrated by the accompanying drawings, in Which- Figure 1 is a transverse sectional view 0f a capsuleeinbodying my invention. Figs. 2 to 20, inclusive, are similar views showing variations in the shape of the capsule.
In carrying` out my invention I make up the compound medicines as capsules, Waters,
pills, or granules 1, of any convenient form,
such as the lentil or double-convex lens or globular, semi-globular, double globular, or of any other preferred shape.
The capsules are each composed of a soluble casing or shell, Which is integral with a soluble partition or partitions 3, formed of the saine material as the shell or casing, for the purpose of dividing the soluble casing into a series of chambers 2, adapted to oontain different kinds of medicine. The Inedicines are preserved entirely separate from each other by the soluble partition or partitions 3, formed integral with the soluble easing, as before explained, and the casing and partition or partit-ions dissolve When taken internally for the purpose of liberating the medicines. The inelosed medicine may be in the form of poWder,uid,or solid, as found best suited to the required treatment.
The medicines so prepared as herein described Inay, if preferred, be dissolved or mixed in water or other suitable fluid or matter and taken as a draft.
I claim- A capsuleconsisting;` of a soluble shell or casing formed integral with a soluble partition to provide separated chambers for different kinds of medicine, said shell or casing and partition dissolving when taken internally for the purpose of liberating the medicines, substantially as described.
Dated this 16th day of June, 189l.
WILLIAM OPPENHEIMIER.
Witnesses:
GEORGE F. DOWNING, SQual'z'ty Oom, London, W. O.
JOSEPH LAKE, 17 Gracechurch Street, London, E. C.
US462990D William oppenheimek Expired - Lifetime US462990A (en)

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Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2452273A (en) * 1945-08-20 1948-10-26 Robert H Van Sant Applicator
US2473368A (en) * 1944-02-25 1949-06-14 Flintermann Gerhard Suppository
US2497212A (en) * 1945-10-31 1950-02-14 Alfonso M Donofrio Method of manufacturing capsules
US2768115A (en) * 1951-11-02 1956-10-23 Bristol Lab Inc Penicillin-aspirin tablets
US3046605A (en) * 1960-01-12 1962-07-31 American Cyanamid Co Manufacture of two-color and two-tone soft shell capsules
US3087606A (en) * 1953-10-19 1963-04-30 Minnesota Mining & Mfg Package of inter-reactive materials
US3345265A (en) * 1963-10-09 1967-10-03 Kendall & Co Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating
US3844285A (en) * 1969-08-28 1974-10-29 Commw Scient Ind Res Org Device for administration to ruminants
US3922338A (en) * 1973-07-12 1975-11-25 Choay Sa Tablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
US4198390A (en) * 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
US4563358A (en) * 1979-01-29 1986-01-07 F. B. Mercer Limited Composite food product and method for making the same
WO1987006128A1 (en) * 1986-04-07 1987-10-22 Clemetson Ab Charles Catechin coated ascorbic acid and method
US4793493A (en) * 1986-09-18 1988-12-27 Makiej Jr Walter J Multidose capsules
US4850489A (en) * 1986-07-11 1989-07-25 Hoechst Aktiengesellschaft Dispensing packs containing pharmaceutical combinations for sequential administration
US5074426A (en) * 1986-11-13 1991-12-24 Warner-Lambert Company Dividable capsule
US5314696A (en) * 1991-06-27 1994-05-24 Paulos Manley A Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
US5824338A (en) * 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
WO1999025629A1 (en) * 1997-11-17 1999-05-27 Merck & Co., Inc. Multicompartment container for combination products
US6428770B1 (en) * 1997-12-03 2002-08-06 Kao Corporation Solid preparation for oral hygiene
WO2010096558A1 (en) 2009-02-18 2010-08-26 Eyeon Particle Sciences Llc Bi-functional co-polymer use for ophthalmic and other topical and local applications
US20110003655A1 (en) * 2009-07-01 2011-01-06 Chernick Mark J Segmented High-Bounce Toy Water Ball
CN102151410A (en) * 2010-02-11 2011-08-17 马克·J·切尔尼克 Toy ball
US8920856B2 (en) 2009-10-08 2014-12-30 Intercontinental Great Brands Llc Co-extruded layered candy and gum apparatus and methods
US9060526B2 (en) 2009-01-22 2015-06-23 Intercontinental Great Brands Llc Confectionery processing
US20150258287A1 (en) * 2013-08-22 2015-09-17 Sipnose Ltd Device to deliver a predetermined amount of a substance to a natural orifice of the body
USD766014S1 (en) * 2014-03-21 2016-09-13 Jin-Young Choi Pillow for baby
US20180200685A1 (en) * 2017-01-11 2018-07-19 Roy C. Putrino Mixing device and methods thereof
USD864151S1 (en) * 2017-10-20 2019-10-22 Shenzhen Fogaap Technologies Co., Ltd. Earphones
US11116914B2 (en) 2014-11-09 2021-09-14 Sipnose Ltd. Device and method for aerosolized delivering of substance to a natural orifice of the body
US11278682B2 (en) 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US11471618B2 (en) 2014-11-09 2022-10-18 Sipnose Ltd. Adjustable dosing delivery and multi sectioned drug compartment

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2473368A (en) * 1944-02-25 1949-06-14 Flintermann Gerhard Suppository
US2452273A (en) * 1945-08-20 1948-10-26 Robert H Van Sant Applicator
US2497212A (en) * 1945-10-31 1950-02-14 Alfonso M Donofrio Method of manufacturing capsules
US2768115A (en) * 1951-11-02 1956-10-23 Bristol Lab Inc Penicillin-aspirin tablets
US3087606A (en) * 1953-10-19 1963-04-30 Minnesota Mining & Mfg Package of inter-reactive materials
US3046605A (en) * 1960-01-12 1962-07-31 American Cyanamid Co Manufacture of two-color and two-tone soft shell capsules
US3345265A (en) * 1963-10-09 1967-10-03 Kendall & Co Multiple layer tablet with calcium salt central core separated from soluble fluoride outer coating
US3844285A (en) * 1969-08-28 1974-10-29 Commw Scient Ind Res Org Device for administration to ruminants
US3922338A (en) * 1973-07-12 1975-11-25 Choay Sa Tablets containing in their mass controlled-release micro-capsules and process for manufacture of said tablets
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
US4563358A (en) * 1979-01-29 1986-01-07 F. B. Mercer Limited Composite food product and method for making the same
US4198390A (en) * 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
WO1987006128A1 (en) * 1986-04-07 1987-10-22 Clemetson Ab Charles Catechin coated ascorbic acid and method
US4850489A (en) * 1986-07-11 1989-07-25 Hoechst Aktiengesellschaft Dispensing packs containing pharmaceutical combinations for sequential administration
US4793493A (en) * 1986-09-18 1988-12-27 Makiej Jr Walter J Multidose capsules
US5074426A (en) * 1986-11-13 1991-12-24 Warner-Lambert Company Dividable capsule
US5558878A (en) * 1991-06-27 1996-09-24 Captab, L.L.C. Method for blinding a tableted medication
US5576019A (en) * 1991-06-27 1996-11-19 Captab 11C Method for blinding a medication
US5314696A (en) * 1991-06-27 1994-05-24 Paulos Manley A Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
US5824338A (en) * 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
WO1999025629A1 (en) * 1997-11-17 1999-05-27 Merck & Co., Inc. Multicompartment container for combination products
US6428770B1 (en) * 1997-12-03 2002-08-06 Kao Corporation Solid preparation for oral hygiene
US9060526B2 (en) 2009-01-22 2015-06-23 Intercontinental Great Brands Llc Confectionery processing
EP3246048A1 (en) 2009-02-18 2017-11-22 Eyeon Particle Sciences LLC Bi-functional co-polymer use for ophthalmic and other topical and local applications
WO2010096558A1 (en) 2009-02-18 2010-08-26 Eyeon Particle Sciences Llc Bi-functional co-polymer use for ophthalmic and other topical and local applications
US20110003655A1 (en) * 2009-07-01 2011-01-06 Chernick Mark J Segmented High-Bounce Toy Water Ball
US8920856B2 (en) 2009-10-08 2014-12-30 Intercontinental Great Brands Llc Co-extruded layered candy and gum apparatus and methods
CN102151410A (en) * 2010-02-11 2011-08-17 马克·J·切尔尼克 Toy ball
US20150258287A1 (en) * 2013-08-22 2015-09-17 Sipnose Ltd Device to deliver a predetermined amount of a substance to a natural orifice of the body
US11383048B2 (en) * 2013-08-22 2022-07-12 Sipnose Ltd. Device to deliver a predetermined amount of a substance to a natural orifice of the body
USD766014S1 (en) * 2014-03-21 2016-09-13 Jin-Young Choi Pillow for baby
US11116914B2 (en) 2014-11-09 2021-09-14 Sipnose Ltd. Device and method for aerosolized delivering of substance to a natural orifice of the body
US11278682B2 (en) 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US11471618B2 (en) 2014-11-09 2022-10-18 Sipnose Ltd. Adjustable dosing delivery and multi sectioned drug compartment
US20180200685A1 (en) * 2017-01-11 2018-07-19 Roy C. Putrino Mixing device and methods thereof
US10835881B2 (en) * 2017-01-11 2020-11-17 Roy C. Putrino Mixing device and methods thereof
USD864151S1 (en) * 2017-10-20 2019-10-22 Shenzhen Fogaap Technologies Co., Ltd. Earphones

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