US5702343A - Cardiac reinforcement device - Google Patents

Cardiac reinforcement device Download PDF

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Publication number
US5702343A
US5702343A US08/720,556 US72055696A US5702343A US 5702343 A US5702343 A US 5702343A US 72055696 A US72055696 A US 72055696A US 5702343 A US5702343 A US 5702343A
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US
United States
Prior art keywords
jacket
heart
cardiac
reinforcement device
epicardial surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US08/720,556
Inventor
Clifton A. Alferness
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mardil Inc
Original Assignee
Acorn Cardiovascular Inc
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Publication date
Application filed by Acorn Cardiovascular Inc filed Critical Acorn Cardiovascular Inc
Priority to US08/720,556 priority Critical patent/US5702343A/en
Assigned to ACORN MEDICAL, INC. reassignment ACORN MEDICAL, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ALFERNESS, CLIFTON A.
Priority to US08/935,440 priority patent/US6126590A/en
Priority to US08/935,723 priority patent/US6077218A/en
Priority to PCT/US1997/017898 priority patent/WO1998014136A1/en
Priority to CA002451964A priority patent/CA2451964A1/en
Priority to AU47450/97A priority patent/AU723460B2/en
Priority to NZ506663A priority patent/NZ506663A/en
Priority to DE29724206U priority patent/DE29724206U1/en
Priority to NZ515821A priority patent/NZ515821A/en
Priority to DE69731890T priority patent/DE69731890T2/en
Priority to NZ335051A priority patent/NZ335051A/en
Priority to AT97909962T priority patent/ATE284180T1/en
Priority to EP97909962A priority patent/EP0930856B1/en
Priority to CA002267104A priority patent/CA2267104C/en
Priority to ARP970104536A priority patent/AR013611A1/en
Publication of US5702343A publication Critical patent/US5702343A/en
Application granted granted Critical
Assigned to ACORN CARDIOVASCULAR, INC. reassignment ACORN CARDIOVASCULAR, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ACORN MEDICAL, INC.
Priority to US09/376,812 priority patent/US6165121A/en
Priority to US09/483,466 priority patent/US6165122A/en
Priority to US09/696,651 priority patent/US6375608B1/en
Priority to US10/084,806 priority patent/US6544168B2/en
Priority to US10/367,346 priority patent/US6893392B2/en
Priority to US10/668,918 priority patent/US7166071B2/en
Priority to US10/668,528 priority patent/US20040059181A1/en
Priority to US10/668,460 priority patent/US7163507B2/en
Priority to US10/672,227 priority patent/US7255674B2/en
Priority to US10/672,226 priority patent/US7261684B2/en
Priority to US10/794,320 priority patent/US7278964B2/en
Priority to US10/810,099 priority patent/US7351200B2/en
Priority to US11/469,224 priority patent/US20070004962A1/en
Priority to US11/750,623 priority patent/US20070225547A1/en
Assigned to MARDIL, INC. reassignment MARDIL, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ACORN CARDIOVASCULAR, INC.
Assigned to MARDIL, INC. reassignment MARDIL, INC. CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNMENT DOCUMENT A COPY OF WHICH WAS INCOMPLETE WHEN SUBMITTED PREVIOUSLY RECORDED ON REEL 026558 FRAME 0507. ASSIGNOR(S) HEREBY CONFIRMS THE COMPLETENESS OF THE ATTACHED ASSIGNMENT DOCUMENT. Assignors: ACORN CARDIOVASCULAR, INC.
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Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2478Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
    • A61F2/2481Devices outside the heart wall, e.g. bags, strips or bands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/161Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel mechanically acting upon the outside of the patient's blood vessel structure, e.g. compressive structures placed around a vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/247Positive displacement blood pumps
    • A61M60/253Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • A61M60/465Details relating to driving for devices for mechanical circulatory actuation
    • A61M60/47Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2478Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
    • A61F2/2481Devices outside the heart wall, e.g. bags, strips or bands
    • A61F2002/2484Delivery devices therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0003Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having an inflatable pocket filled with fluid, e.g. liquid or gas

Definitions

  • the present invention is generally directed to a device and method for reinforcement of the cardiac wall.
  • the invention is particularly suited for the treatment of cardiac disease which result in atrial or ventricular dilation.
  • the invention provides reinforcement of the cardiac wall during diastolic chamber filling to prevent or reduce cardiac dilation in patients known to have experienced such dilation or who have a predisposition for such dilation occurring in the future.
  • the cardiac reinforcement structure is typically applied to the epicardial surface of the heart.
  • Cardiac dilation occurs with different forms of cardiac disease, including heart failure.
  • the dilation may be localized to only a portion of the heart.
  • hypertrophic cardiomyopathy there is typically increased resistance to filling of the left ventricle with concomitant dilation of the left atria.
  • dilated cardiomyopathy the dilation is typically of the left ventricle with resultant failure of the heart as a pump.
  • dilated cardiomyopathy involves the majority of the heart.
  • Drugs are sometimes employed to assist in treating problems associated with cardiac dilation.
  • digoxin increases the contractility of the cardiac muscle and thereby causes enhanced emptying of the dilated cardiac chambers.
  • some drugs for example, beta-blocking drugs, decrease the contractility of the heart and thus increase the likelihood of dilation.
  • Other drugs including angiotensin-converting enzyme inhibitors such as enalopril help to reduce the tendency of the heart to dilate under the increased diastolic pressure experienced when the contractility of the heart muscle decreases. Many of these drugs, however, have side effects which make them undesirable for long-term use.
  • a cardiac reinforcement device includes a biomedical material which can be applied to the epicardial surface of the heart and which expands to a predetermined size that is selected to constrain cardiac expansion beyond a predetermined limit.
  • a biomedical material suitable for a cardiac reinforcement device can be an elastic or non-elastic mesh or non-mesh material.
  • a cardiac reinforcement device is a biomedical material in the form of a patch.
  • the size of the patch is selected to locally constrain cardiac expansion.
  • a cardiac reinforcement device is a biomedical material shaped as a jacket with a predetermined size selected for the jacket to surround the epicardial surface of the heart and circumferentially constrain cardiac expansion.
  • a cardiac reinforcement jacket may be applied to the epicardial surface via a minimally invasive procedure such as thorascopy.
  • a cardiac reinforcement jacket can include a securing arrangement for securing the jacket to the epicardial surface of the heart.
  • the cardiac reinforcement jacket can also include a mechanism for selectively adjusting the predetermined size of the jacket around the epicardial surface of the heart.
  • the adjustment mechanism can include a slot having opposing lateral edges which when pulled together decrease the volumetric size of the jacket.
  • a selective size adjustment mechanism can include an inflatable member mounted between the jacket and the epicardial surface of the heart. Inflation of the inflatable member provides for reduction in the volumetric size of the jacket.
  • a cardiac reinforcement device of the invention can be used to treat cardiomyopathy or to reduce the diastolic volume of the heart.
  • FIG. 1 is a frontal view of one embodiment of a cardiac reinforcement patch.
  • FIG. 2 is a perspective view of the cardiac reinforcement patch of FIG. 1 in place on the epicardium of a heart.
  • FIG. 3 is a perspective view of one embodiment of a cardiac reinforcement jacket according to the invention.
  • FIG. 4 is a second embodiment of a cardiac reinforcement jacket according to the invention.
  • FIG. 5 is a perspective view of the embodiment of the cardiac reinforcement jacket shown in FIG. 3 in place around the heart.
  • FIG. 6 is a schematic cross sectional view of one embodiment of a mechanism for selectively adjusting the predetermined size of a cardiac reinforcement jacket.
  • FIG. 7 is a perspective view of a placement tool which can be used for applying a cardiac reinforcement jacket.
  • FIG. 8 is a perspective view of a placement tool being employed to place a cardiac reinforcement jacket over the heart.
  • the present invention is directed to reinforcement of the heart wall during diastolic filling of a chamber of the heart.
  • the invention is particularly suited for use in cardiomyopathies where abnormal dilation of one or more chambers of the heart is a component of the disease.
  • cardiac chamber refers to the left or right atrium or the left or right ventricle.
  • myocardium refers to the cardiac muscle comprising the contractile walls of the heart.
  • endocardial surface refers to the inner walls of the heart.
  • endocardial surface refers to the outer walls of the heart.
  • the heart is enclosed within a double walled sac known as the pericardium.
  • the inner layer of the pericardial sac is the visceral pericardium or epicardium.
  • the outer layer of the pericardial sac is the parietal pericardium.
  • a cardiac reinforcement device limits the outward expansion of the heart wall during diastolic chamber filling beyond a predetermined size.
  • the expansion constraint applied to the heart by a CRD is predetermined by the physician based on, for example, cardiac output performance or cardiac volume.
  • a CRD according to the present disclosure provides cardiac reinforcement during diastole.
  • a CRD is made from a biomedical material which can be applied to the epicardial surface of the heart.
  • a biomedical material is a material which is physiologically inert to avoid rejection or other negative inflammatory response.
  • a CRD can be prepared from an elastic or substantially non-elastic biomedical material.
  • the biomedical material can be inflexible, but is preferably sufficiently flexible to move with the expansion and contraction of the heart without impairing systolic function.
  • the biomedical material should, however, constrain cardiac expansion, during diastolic filling of the heart, to a predetermined size.
  • suitable biomedical materials include perforate and non-perforate materials.
  • Perforate materials include, for example, a mesh such as a polypropylene or polyester mesh.
  • Non-perforate materials include, for example, silicone rubber.
  • a biomedical material suitable for a device of the invention generally has a lower compliance than the heart wall. Even though the biomedical material is less compliant than the heart wall, some limited expansion of an elastic biomedical material can occur during cardiac filling.
  • the biomedical material can be substantially non-elastic.
  • substantially non-elastic refers to a material which constrains cardiac expansion during diastole at a predetermined size, but which has substantially no elastic properties.
  • a CRD advantageous to a CRD according to the present disclosure is cardiac reinforcement which is provided during diastole. Moreover, a CRD as disclosed herein does not provide cardiac assistance through active pumping of the heart.
  • a cardiac reinforcement device provides for local constraint of the heart wall during cardiac expansion.
  • a CRD is a "patch” that provides reinforcement of the heart wall at a localized area, such as a cardiac aneurysm or at an area of the myocardium which has been damaged due to myocardial infarction.
  • predetermined size of the patch means that the size of the patch is selected to cover an area of the epicardial surface of the heart in need of reinforcement without completely surrounding the circumference of the heart.
  • a CRD patch can be prepared from the biomedical materials described above.
  • the patch is an open mesh material.
  • a CRD patch can be applied to the epicardial surface of the heart over or under the parietal pericardium.
  • a patch is typically applied to the epicardial surface by suturing around the periphery of the patch.
  • the peripheral edge of the patch can include a thickened "ring" or other reinforcement to enhance the strength of the patch at the point of suture attachment to the epicardium.
  • a patch is applied to the epicardium through a thoracotomy or other incision providing sufficient exposure of the heart.
  • a CRD is a jacket that circumferentially surrounds the epicardial surface of the heart.
  • a CRD jacket When applied to the heart, a CRD jacket can be placed over or under the parietal pericardium.
  • predetermined size refers to the predetermined expansion limit of the jacket which circumferentially constrains cardiac expansion during diastolic filling of the heart.
  • a physician could measure cardiac output and adjust the jacket size to an optimal size for the desired effect.
  • the optimal size is the "predetermined size"
  • the predetermined size can be adjusted for size reduction as the cardiac size is reduced.
  • the CRD jacket is a coneshaped tube, having a base broader than the apex, which generally conforms to the external geometry of the heart.
  • the base of the jacket When applied to the epicardial surface of the heart, the base of the jacket is oriented towards the base of the heart, and the apex of the jacket is oriented towards the apex of the heart.
  • the base of the jacket includes an opening for applying the jacket by passing the jacket over the epicardial surface of the heart.
  • the apical end of the jacket can be a continuous surface which covers the apex of the heart.
  • the apex of the jacket can have an opening through which the apex of the heart protrudes.
  • a cardiac reinforcement jacket is not an inflatable device that surrounds the heart. Rather, the device is typically a single layer of biomedical material. In one embodiment discussed below, an inflatable member can be included with the device, but the inflatable member serves to reduce the volume within a localized region of the jacket and does not follow the entire jacket to surround the epicardial surface of the heart.
  • the CRD jacket can be secured to the epicardium by a securing arrangement mounted at the base of the jacket.
  • a suitable securing arrangement includes, for example, a circumferential attachment device, such as a cord, suture, band, adhesive or shape memory element which passes around the circumference of the base of the jacket. The ends of the attachment device can be fastened together to secure the jacket in place.
  • the base of the jacket can be reinforced for suturing the base of the jacket to the epicardium.
  • a CRD jacket can include a mechanism for selectively adjusting the size of the jacket.
  • a mechanism for selectively adjusting the volumetric size of the jacket theoretically provides for a "one size fits all" device. More importantly, however, an adjustable jacket provides the ability to titrate (readjust) the amount of cardiac reinforcement by graded reduction in jacket size as therapeutic reduction of cardiac expansion occurs.
  • a mechanism for selectively adjusting the size of the jacket can include a slot which opens at the base of the jacket and extends toward the apex end of the CRD. If the apex end of the CRD jacket is open, the apical extent of the slot can be continuous with the apex opening.
  • the slot includes opposing lateral edges. By adjusting the proximity of the opposing lateral edges, the overall size of the jacket can be varied. Moving the opposing edges of the slot closer together narrows the slot and reduces the volumetric size of the jacket.
  • the opposing edges of the slot can be fastened together at a predetermined proximity by, for example, one or more lateral attachment devices, such as a cord, suture, band, adhesive or shape memory element attached to each lateral edge.
  • a mechanism for selectively adjusting the size of the jacket can be an inflatable member.
  • the inflatable member is mounted between the jacket and the epicardium.
  • the volumetric size of the jacket can be reduced by inflating the inflatable member through an inflation port with, for example, a gas or liquid.
  • the predetermined size of the jacket can then be reduced by inflating the inflatable member within the jacket.
  • the size of the inflatable member is preferably maintained until therapeutic response causes a need for further inflation.
  • the inflation of the inflatable member provides a reduction in the predetermined size of the jacket by a fixed increase in volume of the inflatable member.
  • the inflatable member is not rhythmically inflated and deflated to provide assistance to cardiac contraction during systole.
  • the biomedical material of the invention can be radioluscent or radiopaque.
  • the material of the jacket can be made radiopaque by inclusion of radiopaque markers for identification of the outside surface of the heart, the expansion slot or inflation port.
  • radiopaque means causing the CRD to be visible on x-ray or fluoroscopic viewing.
  • Suitable radiopaque markers include, for example, platinum wires, titanium wires and stainless steel wires.
  • cardiac disease includes diseases in which dilation of one of the chambers of the heart is a component of the disease. Examples include heart failure or cardiomyopathy.
  • Heart failure can occur as a result of cardiac dilation due to ventricular hypertrophy or secondary to, for example, valvular incompetency, valvular insufficiency or valvular stenosis.
  • Cardiomyopathy according to the invention, can be primary or secondary to infection, ischemia, metabolic disease, genetic disorders, etc.
  • constraint of cardiac expansion by a device of the invention can provide reduced cardiac dilation.
  • Reduced cardiac dilation can cause reduction in the problems associated with cardiac dilation such as arrhythmias and valvular leakage.
  • selective reduction of the predetermined size of the jacket also provides continued reinforcement for the size reduced heart.
  • a CRD jacket can also be used to measure cardiac performance.
  • the CRD jacket is rendered radiopaque by use of a radiographic marker.
  • the radiographic markers are distributed throughout the jacket over the surface of the heart. By evaluation of the markers relative to one another with each heart beat, cardiac performance may be measured. As such, evaluation of cardiac performance may assist in adjusting the predetermined size of a CRD jacket.
  • a CRD as described herein can be applied to the epicardium of a heart through a thoracotomy or through a minimally invasive procedure.
  • a CRD placement tool can be used to apply the CRD over the epicardium of the heart through a thorascopic incision.
  • a CRD placement tool includes a cannula, a stiff rod or wire and a guide tube.
  • the wire is threaded through the guide tube which is passed around the circumference of the base of the jacket. The CRD with wire and guide tube passed through the base opening are then passed into the cannula.
  • the cannula is of sufficient length and diameter to enclose the CRD, wire and guide tube during passage of the placement tool through a thorascopic incision.
  • the placement tool is passed into the thoracic cavity and positioned at a point near the apex of the heart.
  • the wire and guide tube are pushed out of the cannula away from the operator.
  • the wire and guide tube sufficiently expand the opening of the base of the CRD jacket to pass over the epicardial surface of the heart.
  • the wire, guide tube and cannula can be removed.
  • a second incision can then be made to provide access for suitable surgical instruments to secure or adjust the size of the CRD.
  • FIG. 1 is a frontal view of one embodiment of a cardiac reinforcement patch 1.
  • the CRD patch 1 shown here is a mesh biomedical material 2 having a thickened peripheral ring 3 which reinforces the peripheral edge 4 of the patch for attachment of the patch to the epicardial surface of the heart.
  • FIG. 2. is a perspective view of a CRD patch 10 in place on the epicardial surface of a heart 11, for example, over a cardiac aneurysm (not shown) of the heart.
  • the patch 10 is sized to cover the extent of the cardiac aneurysm and is placed on the epicardial surface of the heart 11.
  • the thorax is surgically opened and the region of the heart 11 with the aneurysm (not shown) is located and exposed.
  • the patch 10 is placed over the aneurysm and sutured in place around the periphery 12 of the patch to provide sufficient constraint to prevent further dilation of the aneurysm.
  • FIG. 3 is a perspective view of one embodiment of a CRD jacket 15 according to the invention.
  • the jacket 15 is a mesh material 16, and includes a circumferential attachment device 17 at the base end 18 of the CRD jacket.
  • the apex end 24 of the jacket 15 is closed.
  • the jacket 15 shown also includes a slot 19 having opposing lateral edges 20 and 21, and fasteners (e.g. lateral attachment device 22 and 23) for selectively adjusting the volumetric size of the jacket 15.
  • the CRD jacket 15 shown also includes radiopaque markers 25 for visualizing the surface of the heart through radiographic study.
  • FIG. 4 is an alternative embodiment of a CRD jacket 30. Similar to the embodiment shown in FIG. 3, the embodiment of FIG. 4 includes a base end 31 and an apex 32 end. The base end includes a circumferential attachment device 33 for securing the CRD jacket 30 to the heart.
  • the CRD jacket 30 of FIG. 4 also includes a slot 34 having opposing lateral edges 35, 36. The lateral edges 35, 36 are shown pulled together at 37 by a lateral attachment device 38, for example, a suture.
  • the embodiment shown in FIG. 4 has an opening 39 at the apex end 32 of the CRD jacket 30.
  • FIG. 5. is a perspective view of a CRD jacket 40 around a heart 41.
  • a circumferential attachment device 43 which secures the CRD jacket 40 near the base of the heart 44.
  • a slot 45 is shown with opposing lateral edges 46, 47 fastened together by a lateral attachment device 48.
  • the CRD jacket 40 has an opening 49 at the apical end 50 of the jacket. The apex of the heart 51 protrudes through the opening 49 at the apical end 50 of the jacket 40.
  • the device can provide a way of applying a graded constraint around the outside of the heart 41 to reduce cardiac dilation over time.
  • the jacket would be placed over the heart 41 as shown, either over or under the parietal pericardium (not shown).
  • the circumferential attachment device 43 and lateral attachment device 48 would then be tightened to cause a constraining effect on the outside of the heart.
  • lateral attachment cords 48 is made of an elastic material, such as silicone rubber
  • surface pressure exerted on the epicardial surface of the heart varies as a function of the amount of dilation of the heart. This variable pressure has the effect of reducing the cardiac dilation to a certain point and then stopping because the surface pressure drops to a negligible amount.
  • the amount of constraint or reduction in dilation that is accomplished over time and the resultant cardiac performance may be monitored radiographically using techniques known in the art, for example fluoroscopy, by observing radiographic markers (FIG. 4, 25), if present.
  • FIG. 6 is a schematic cross sectional view of an alternative embodiment of an arrangement for selectively adjusting the predetermined size of a jacket 53.
  • an inflatable member 54 is inserted within the jacket 53 between the jacket 53 and the epicardial surface 55 of the heart 56.
  • the inflatable member 54 includes a filling apparatus 57 for entry of a fluid (liquid or gas) to inflate the inflatable member 54 and reduce the predetermined size of the jacket 53.
  • FIG. 7 is a perspective view of a placement tool 60 which can be used for placement of a CRD jacket 61 around the epicardium of the heart. As shown here, the base end of the jacket 62 is held open by guide tube 63 through which is passed a wire or stiffening rod 64. The wire 64 can be removed from the guide tube 63 by pulling on the wire extraction grip 66.
  • the placement tool 60 includes a cannula 65 which encloses the jacket 61, guide tube 63 and wire 64 during insertion of the tool into a thorascopic incision.
  • FIG. 8 is a perspective view of a placement tool 70 being employed to place a jacket 71 over the heart 72 on the outside of the parietal pericardium 73.
  • the placement tool 70 is guided through a small incision in the thorax and the jacket 71 is maneuvered into position over the heart 72.
  • the wire 74 which is passed through the guide tube 75 around the base 76 of the jacket 71, is extracted from the guide tube 75 by pulling on the wire extraction grip 77.
  • the guide tube 75 is then extracted by pulling on the guide tube extraction grip 78.
  • the cannula 79 is removed from the chest and the circumferential attachment cord (not shown in this view), and the lateral attachment cord 80 can be fastened to secure the jacket 71.

Abstract

The present disclosure is directed to a cardiac reinforcement device (CRD) and method for the treatment of cardiomyopathy. The CRD provides for reinforcement of the walls of the heart by constraining cardiac expansion, beyond a predetermined limit, during diastolic expansion of the heart. A CRD of the invention can be applied to the epicardium of the heart to locally constrain expansion of the cardiac wall or to circumferentially constrain the cardiac wall during cardiac expansion.

Description

BACKGROUND OF THE INVENTION
The present invention is generally directed to a device and method for reinforcement of the cardiac wall. The invention is particularly suited for the treatment of cardiac disease which result in atrial or ventricular dilation. The invention provides reinforcement of the cardiac wall during diastolic chamber filling to prevent or reduce cardiac dilation in patients known to have experienced such dilation or who have a predisposition for such dilation occurring in the future. The cardiac reinforcement structure is typically applied to the epicardial surface of the heart.
Cardiac dilation occurs with different forms of cardiac disease, including heart failure. In some cases, such as post-myocardial infarction, the dilation may be localized to only a portion of the heart. In other cases, such as hypertrophic cardiomyopathy, there is typically increased resistance to filling of the left ventricle with concomitant dilation of the left atria. In dilated cardiomyopathy, the dilation is typically of the left ventricle with resultant failure of the heart as a pump. In advanced cases, dilated cardiomyopathy involves the majority of the heart.
With each type of cardiac dilation, there are associated problems ranging from arrhythmias which arise due to the stretch of myocardial cells, to leakage of the cardiac valves due to enlargement of the valvular annulus. Devices to prevent or reduce dilation and thereby reduce the consequences of dilation have not been described. Patches made from low porosity materials, for example Dacron™, have been used to repair cardiac ruptures and septal defects, but the use of patches to support the cardiac wall where no penetrating lesion is present has not been described.
Drugs are sometimes employed to assist in treating problems associated with cardiac dilation. For example, digoxin increases the contractility of the cardiac muscle and thereby causes enhanced emptying of the dilated cardiac chambers. On the other hand, some drugs, for example, beta-blocking drugs, decrease the contractility of the heart and thus increase the likelihood of dilation. Other drugs including angiotensin-converting enzyme inhibitors such as enalopril help to reduce the tendency of the heart to dilate under the increased diastolic pressure experienced when the contractility of the heart muscle decreases. Many of these drugs, however, have side effects which make them undesirable for long-term use.
Accordingly, there is a need for a device that can reduce or prevent cardiac dilation and reduce the problems associated with such dilation.
SUMMARY OF THE INVENTION
The present invention is directed to a device and method for reinforcement of the cardiac wall. According to the invention, a cardiac reinforcement device includes a biomedical material which can be applied to the epicardial surface of the heart and which expands to a predetermined size that is selected to constrain cardiac expansion beyond a predetermined limit. A biomedical material suitable for a cardiac reinforcement device can be an elastic or non-elastic mesh or non-mesh material.
In one embodiment, a cardiac reinforcement device is a biomedical material in the form of a patch. The size of the patch is selected to locally constrain cardiac expansion.
In another embodiment, a cardiac reinforcement device is a biomedical material shaped as a jacket with a predetermined size selected for the jacket to surround the epicardial surface of the heart and circumferentially constrain cardiac expansion. In one embodiment, a cardiac reinforcement jacket may be applied to the epicardial surface via a minimally invasive procedure such as thorascopy.
A cardiac reinforcement jacket can include a securing arrangement for securing the jacket to the epicardial surface of the heart. The cardiac reinforcement jacket can also include a mechanism for selectively adjusting the predetermined size of the jacket around the epicardial surface of the heart. The adjustment mechanism can include a slot having opposing lateral edges which when pulled together decrease the volumetric size of the jacket. In an alternative embodiment, a selective size adjustment mechanism can include an inflatable member mounted between the jacket and the epicardial surface of the heart. Inflation of the inflatable member provides for reduction in the volumetric size of the jacket.
A cardiac reinforcement device of the invention can be used to treat cardiomyopathy or to reduce the diastolic volume of the heart.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a frontal view of one embodiment of a cardiac reinforcement patch.
FIG. 2 is a perspective view of the cardiac reinforcement patch of FIG. 1 in place on the epicardium of a heart.
FIG. 3 is a perspective view of one embodiment of a cardiac reinforcement jacket according to the invention.
FIG. 4 is a second embodiment of a cardiac reinforcement jacket according to the invention.
FIG. 5 is a perspective view of the embodiment of the cardiac reinforcement jacket shown in FIG. 3 in place around the heart.
FIG. 6 is a schematic cross sectional view of one embodiment of a mechanism for selectively adjusting the predetermined size of a cardiac reinforcement jacket.
FIG. 7 is a perspective view of a placement tool which can be used for applying a cardiac reinforcement jacket.
FIG. 8 is a perspective view of a placement tool being employed to place a cardiac reinforcement jacket over the heart.
DETAILED DESCRIPTION
The present invention is directed to reinforcement of the heart wall during diastolic filling of a chamber of the heart. The invention is particularly suited for use in cardiomyopathies where abnormal dilation of one or more chambers of the heart is a component of the disease.
As used herein, "cardiac chamber" refers to the left or right atrium or the left or right ventricle. The term "myocardium" refers to the cardiac muscle comprising the contractile walls of the heart. The term "endocardial surface" refers to the inner walls of the heart. The term "epicardial surface " refers to the outer walls of the heart.
The heart is enclosed within a double walled sac known as the pericardium. The inner layer of the pericardial sac is the visceral pericardium or epicardium. The outer layer of the pericardial sac is the parietal pericardium.
According to the present invention, a cardiac reinforcement device (CRD) limits the outward expansion of the heart wall during diastolic chamber filling beyond a predetermined size. The expansion constraint applied to the heart by a CRD is predetermined by the physician based on, for example, cardiac output performance or cardiac volume. In contrast to known ventricular assist devices which provide cardiac assistance during systole, a CRD according to the present disclosure provides cardiac reinforcement during diastole.
A CRD is made from a biomedical material which can be applied to the epicardial surface of the heart. As used herein, a "biomedical material" is a material which is physiologically inert to avoid rejection or other negative inflammatory response. A CRD can be prepared from an elastic or substantially non-elastic biomedical material. The biomedical material can be inflexible, but is preferably sufficiently flexible to move with the expansion and contraction of the heart without impairing systolic function. The biomedical material should, however, constrain cardiac expansion, during diastolic filling of the heart, to a predetermined size. Examples of suitable biomedical materials include perforate and non-perforate materials. Perforate materials include, for example, a mesh such as a polypropylene or polyester mesh. Non-perforate materials include, for example, silicone rubber.
A biomedical material suitable for a device of the invention generally has a lower compliance than the heart wall. Even though the biomedical material is less compliant than the heart wall, some limited expansion of an elastic biomedical material can occur during cardiac filling.
In an alternative embodiment, the biomedical material can be substantially non-elastic. According to this embodiment, the term "substantially non-elastic" refers to a material which constrains cardiac expansion during diastole at a predetermined size, but which has substantially no elastic properties.
Regardless if the biomedical material is elastic or non-elastic, advantageous to a CRD according to the present disclosure is cardiac reinforcement which is provided during diastole. Moreover, a CRD as disclosed herein does not provide cardiac assistance through active pumping of the heart.
I. CRD Patch
In one embodiment, a cardiac reinforcement device (CRD) provides for local constraint of the heart wall during cardiac expansion. According to this embodiment, a CRD is a "patch" that provides reinforcement of the heart wall at a localized area, such as a cardiac aneurysm or at an area of the myocardium which has been damaged due to myocardial infarction. When discussing a "patch", "predetermined size" of the patch means that the size of the patch is selected to cover an area of the epicardial surface of the heart in need of reinforcement without completely surrounding the circumference of the heart.
A CRD patch can be prepared from the biomedical materials described above. In a preferred embodiment, the patch is an open mesh material.
A CRD patch can be applied to the epicardial surface of the heart over or under the parietal pericardium. A patch is typically applied to the epicardial surface by suturing around the periphery of the patch. The peripheral edge of the patch can include a thickened "ring" or other reinforcement to enhance the strength of the patch at the point of suture attachment to the epicardium. Generally, a patch is applied to the epicardium through a thoracotomy or other incision providing sufficient exposure of the heart.
II. CRD Jacket
In another embodiment, a CRD is a jacket that circumferentially surrounds the epicardial surface of the heart. When applied to the heart, a CRD jacket can be placed over or under the parietal pericardium.
A CRD applied to the epicardium is fitted to a "predetermined size" for limitation of cardiac expansion. According to a jacket embodiment, "predetermined size" refers to the predetermined expansion limit of the jacket which circumferentially constrains cardiac expansion during diastolic filling of the heart. In practice, for example, a physician could measure cardiac output and adjust the jacket size to an optimal size for the desired effect. In this example, the optimal size is the "predetermined size" In one embodiment, the predetermined size can be adjusted for size reduction as the cardiac size is reduced.
In one embodiment, the CRD jacket is a coneshaped tube, having a base broader than the apex, which generally conforms to the external geometry of the heart. When applied to the epicardial surface of the heart, the base of the jacket is oriented towards the base of the heart, and the apex of the jacket is oriented towards the apex of the heart. Typically, the base of the jacket includes an opening for applying the jacket by passing the jacket over the epicardial surface of the heart. The apical end of the jacket can be a continuous surface which covers the apex of the heart. Alternatively, the apex of the jacket can have an opening through which the apex of the heart protrudes.
A cardiac reinforcement jacket, as disclosed herein, is not an inflatable device that surrounds the heart. Rather, the device is typically a single layer of biomedical material. In one embodiment discussed below, an inflatable member can be included with the device, but the inflatable member serves to reduce the volume within a localized region of the jacket and does not follow the entire jacket to surround the epicardial surface of the heart.
In one embodiment, the CRD jacket can be secured to the epicardium by a securing arrangement mounted at the base of the jacket. A suitable securing arrangement includes, for example, a circumferential attachment device, such as a cord, suture, band, adhesive or shape memory element which passes around the circumference of the base of the jacket. The ends of the attachment device can be fastened together to secure the jacket in place. Alternatively, the base of the jacket can be reinforced for suturing the base of the jacket to the epicardium.
Various sized CRD jackets can be prepared such that different sized jackets are used for different predetermined cardiac expansion sizes or expansion ranges. Alternatively, a CRD jacket can include a mechanism for selectively adjusting the size of the jacket. A mechanism for selectively adjusting the volumetric size of the jacket theoretically provides for a "one size fits all" device. More importantly, however, an adjustable jacket provides the ability to titrate (readjust) the amount of cardiac reinforcement by graded reduction in jacket size as therapeutic reduction of cardiac expansion occurs.
A mechanism for selectively adjusting the size of the jacket can include a slot which opens at the base of the jacket and extends toward the apex end of the CRD. If the apex end of the CRD jacket is open, the apical extent of the slot can be continuous with the apex opening. The slot includes opposing lateral edges. By adjusting the proximity of the opposing lateral edges, the overall size of the jacket can be varied. Moving the opposing edges of the slot closer together narrows the slot and reduces the volumetric size of the jacket. The opposing edges of the slot can be fastened together at a predetermined proximity by, for example, one or more lateral attachment devices, such as a cord, suture, band, adhesive or shape memory element attached to each lateral edge.
In another embodiment, a mechanism for selectively adjusting the size of the jacket can be an inflatable member. According to this embodiment, the inflatable member is mounted between the jacket and the epicardium. The volumetric size of the jacket can be reduced by inflating the inflatable member through an inflation port with, for example, a gas or liquid. As cardiac expansion volume responds to cardiac constraint by size reduction, the predetermined size of the jacket can then be reduced by inflating the inflatable member within the jacket. Once inflated, the size of the inflatable member is preferably maintained until therapeutic response causes a need for further inflation. According to the invention, the inflation of the inflatable member provides a reduction in the predetermined size of the jacket by a fixed increase in volume of the inflatable member. The inflatable member is not rhythmically inflated and deflated to provide assistance to cardiac contraction during systole.
The biomedical material of the invention can be radioluscent or radiopaque. In one embodiment, the material of the jacket can be made radiopaque by inclusion of radiopaque markers for identification of the outside surface of the heart, the expansion slot or inflation port. As used herein, radiopaque means causing the CRD to be visible on x-ray or fluoroscopic viewing. Suitable radiopaque markers include, for example, platinum wires, titanium wires and stainless steel wires.
A CRD according to the present disclosure provides a new method for the treatment of cardiac disease. As used herein, cardiac disease includes diseases in which dilation of one of the chambers of the heart is a component of the disease. Examples include heart failure or cardiomyopathy. Heart failure can occur as a result of cardiac dilation due to ventricular hypertrophy or secondary to, for example, valvular incompetency, valvular insufficiency or valvular stenosis. Cardiomyopathy, according to the invention, can be primary or secondary to infection, ischemia, metabolic disease, genetic disorders, etc.
It is foreseen that constraint of cardiac expansion by a device of the invention can provide reduced cardiac dilation. Reduced cardiac dilation can cause reduction in the problems associated with cardiac dilation such as arrhythmias and valvular leakage. As reduction of cardiac dilation occurs, selective reduction of the predetermined size of the jacket also provides continued reinforcement for the size reduced heart.
A CRD jacket can also be used to measure cardiac performance. According to this embodiment, the CRD jacket is rendered radiopaque by use of a radiographic marker. The radiographic markers are distributed throughout the jacket over the surface of the heart. By evaluation of the markers relative to one another with each heart beat, cardiac performance may be measured. As such, evaluation of cardiac performance may assist in adjusting the predetermined size of a CRD jacket.
A CRD as described herein can be applied to the epicardium of a heart through a thoracotomy or through a minimally invasive procedure. For a minimally invasive procedure a CRD placement tool can be used to apply the CRD over the epicardium of the heart through a thorascopic incision. According to this embodiment, a CRD placement tool includes a cannula, a stiff rod or wire and a guide tube. For placement of a CRD, the wire is threaded through the guide tube which is passed around the circumference of the base of the jacket. The CRD with wire and guide tube passed through the base opening are then passed into the cannula. The cannula is of sufficient length and diameter to enclose the CRD, wire and guide tube during passage of the placement tool through a thorascopic incision. The placement tool is passed into the thoracic cavity and positioned at a point near the apex of the heart. When in position, the wire and guide tube are pushed out of the cannula away from the operator. Once outside the cannula, the wire and guide tube sufficiently expand the opening of the base of the CRD jacket to pass over the epicardial surface of the heart. When the CRD jacket is in position over the epicardial surface, the wire, guide tube and cannula can be removed. A second incision can then be made to provide access for suitable surgical instruments to secure or adjust the size of the CRD.
The invention will now be further described by reference to the drawings.
FIG. 1 is a frontal view of one embodiment of a cardiac reinforcement patch 1. The CRD patch 1 shown here is a mesh biomedical material 2 having a thickened peripheral ring 3 which reinforces the peripheral edge 4 of the patch for attachment of the patch to the epicardial surface of the heart.
FIG. 2. is a perspective view of a CRD patch 10 in place on the epicardial surface of a heart 11, for example, over a cardiac aneurysm (not shown) of the heart. In one preferred embodiment, the patch 10 is sized to cover the extent of the cardiac aneurysm and is placed on the epicardial surface of the heart 11. In practice, the thorax is surgically opened and the region of the heart 11 with the aneurysm (not shown) is located and exposed. The patch 10 is placed over the aneurysm and sutured in place around the periphery 12 of the patch to provide sufficient constraint to prevent further dilation of the aneurysm.
FIG. 3 is a perspective view of one embodiment of a CRD jacket 15 according to the invention. According to the embodiment shown, the jacket 15 is a mesh material 16, and includes a circumferential attachment device 17 at the base end 18 of the CRD jacket. The apex end 24 of the jacket 15 is closed. The jacket 15 shown also includes a slot 19 having opposing lateral edges 20 and 21, and fasteners (e.g. lateral attachment device 22 and 23) for selectively adjusting the volumetric size of the jacket 15. The CRD jacket 15 shown also includes radiopaque markers 25 for visualizing the surface of the heart through radiographic study.
FIG. 4 is an alternative embodiment of a CRD jacket 30. Similar to the embodiment shown in FIG. 3, the embodiment of FIG. 4 includes a base end 31 and an apex 32 end. The base end includes a circumferential attachment device 33 for securing the CRD jacket 30 to the heart. The CRD jacket 30 of FIG. 4 also includes a slot 34 having opposing lateral edges 35, 36. The lateral edges 35, 36 are shown pulled together at 37 by a lateral attachment device 38, for example, a suture. In contrast to the embodiment shown in FIG. 3, the embodiment shown in FIG. 4 has an opening 39 at the apex end 32 of the CRD jacket 30.
FIG. 5. is a perspective view of a CRD jacket 40 around a heart 41. According to the embodiment shown, at the base 42 of the jacket 40, there is a circumferential attachment device 43 which secures the CRD jacket 40 near the base of the heart 44. A slot 45, is shown with opposing lateral edges 46, 47 fastened together by a lateral attachment device 48. In the embodiment shown, the CRD jacket 40 has an opening 49 at the apical end 50 of the jacket. The apex of the heart 51 protrudes through the opening 49 at the apical end 50 of the jacket 40.
Still referring to FIG. 5, in a preferred embodiment, if one or more of the lateral attachment device 48 are made of an elastic material, such as silicone rubber, the device can provide a way of applying a graded constraint around the outside of the heart 41 to reduce cardiac dilation over time. In practice, the jacket would be placed over the heart 41 as shown, either over or under the parietal pericardium (not shown). The circumferential attachment device 43 and lateral attachment device 48 would then be tightened to cause a constraining effect on the outside of the heart.
In a preferred embodiment, if one or more of the lateral attachment cords 48 is made of an elastic material, such as silicone rubber, surface pressure exerted on the epicardial surface of the heart varies as a function of the amount of dilation of the heart. This variable pressure has the effect of reducing the cardiac dilation to a certain point and then stopping because the surface pressure drops to a negligible amount. The amount of constraint or reduction in dilation that is accomplished over time and the resultant cardiac performance may be monitored radiographically using techniques known in the art, for example fluoroscopy, by observing radiographic markers (FIG. 4, 25), if present.
FIG. 6 is a schematic cross sectional view of an alternative embodiment of an arrangement for selectively adjusting the predetermined size of a jacket 53. According to this embodiment, an inflatable member 54 is inserted within the jacket 53 between the jacket 53 and the epicardial surface 55 of the heart 56. The inflatable member 54 includes a filling apparatus 57 for entry of a fluid (liquid or gas) to inflate the inflatable member 54 and reduce the predetermined size of the jacket 53.
FIG. 7 is a perspective view of a placement tool 60 which can be used for placement of a CRD jacket 61 around the epicardium of the heart. As shown here, the base end of the jacket 62 is held open by guide tube 63 through which is passed a wire or stiffening rod 64. The wire 64 can be removed from the guide tube 63 by pulling on the wire extraction grip 66. The placement tool 60 includes a cannula 65 which encloses the jacket 61, guide tube 63 and wire 64 during insertion of the tool into a thorascopic incision.
FIG. 8 is a perspective view of a placement tool 70 being employed to place a jacket 71 over the heart 72 on the outside of the parietal pericardium 73. The placement tool 70 is guided through a small incision in the thorax and the jacket 71 is maneuvered into position over the heart 72. Once the jacket 71 is in proper position, the wire 74, which is passed through the guide tube 75 around the base 76 of the jacket 71, is extracted from the guide tube 75 by pulling on the wire extraction grip 77. The guide tube 75 is then extracted by pulling on the guide tube extraction grip 78. The cannula 79 is removed from the chest and the circumferential attachment cord (not shown in this view), and the lateral attachment cord 80 can be fastened to secure the jacket 71.
The above specification and drawings provide a description of a cardiac reinforcement device and method of using on the heart. Since many embodiments of the invention can be made without departing from the spirit and scope of the invention, the invention resides in the claims hereinafter appended.

Claims (14)

What is claimed is:
1. A cardiac reinforcement device, said device comprising:
a jacket of a biomedical material which can be applied to the epicardial surface of the heart and which expands to a predetermined size, said predetermined size selected to surround the epicardial surface of the heart and circumferentially constrain cardiac expansion beyond a predetermined limit, said jacket comprising:
(i) a base end, said base end having an opening for applying said jacket to the epicardial surface of the heart by passing said jacket over the epicardial surface of the heart such that when applied to said epicardial surface, said base end of said jacket is oriented toward the base of the heart; and (ii) a slot for selectively adjusting said predetermined size of said jacket, said slot having opposing lateral edges which decrease said predetermined size of said jacket by moving said opposing lateral edges together.
2. The cardiac reinforcement device according to claim 1 including a lateral attachment device for fastening together said lateral opposing edges of said slot.
3. The cardiac reinforcement device according to claim 1 further comprising an inflatable member mounted between said jacket and the epicardial surface for selectively adjusting said predetermined size of said jacket.
4. The cardiac reinforcement device according to claim 1 wherein said biomedical material is an open mesh material.
5. The cardiac reinforcement device according to claim 1 wherein said biomedical material is a polyester mesh.
6. The cardiac reinforcement device according to claim 1 wherein said biomedical material is silicon rubber.
7. The cardiac reinforcement device according to claim 1 wherein said biomedical material includes a radiopaque marker.
8. The cardiac reinforcement device according to claim 7 wherein said radiopaque marker is a platinum wire.
9. A cardiac reinforcement device, said device comprising:
a jacket of a biomedical material which can be applied to the epicardial surface of the heart and which expands to a predetermined size, said predetermined size selected to surround the epicardial surface of the heart and circumferentially constrain cardiac expansion beyond a predetermined limit, said jacket comprising:
(i) a base end, said base end having an opening for applying said jacket to the epieardial surface of the heart by passing said jacket over the epicardial surface of the heart such that when applied to said epicardial surface, said base end of said jacket is oriented toward the base of the heart; and
(ii) an inflatable member mounted between said jacket and the epicardial surface of the heart for selectively adjusting said predetermined size of said jacket.
10. The cardiac reinforcement device according to claim 9 wherein said biomedical material is an open mesh material.
11. The cardiac reinforcement device according to claim 9 wherein said biomedical material is a polyester mesh.
12. The cardiac reinforcement device according to claim 9 wherein said biomedical material is silicon rubber.
13. The cardiac reinforcement device according to claim 9 wherein said biomedical material includes a radiopaque marker.
14. The cardiac reinforcement device according to claim 13 wherein said radiopaque marker is a platinum wire.
US08/720,556 1996-10-02 1996-10-02 Cardiac reinforcement device Expired - Lifetime US5702343A (en)

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US08/720,556 US5702343A (en) 1996-10-02 1996-10-02 Cardiac reinforcement device
US08/935,440 US6126590A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device
US08/935,723 US6077218A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device
NZ515821A NZ515821A (en) 1996-10-02 1997-10-01 Method for reinforcement of cardiac wall
NZ335051A NZ335051A (en) 1996-10-02 1997-10-01 Heart volume limiting device
AU47450/97A AU723460B2 (en) 1996-10-02 1997-10-01 Heart volume limiting device
NZ506663A NZ506663A (en) 1996-10-02 1997-10-01 Heart volume limiting device of cone shape and open cells
DE29724206U DE29724206U1 (en) 1996-10-02 1997-10-01 Device for restricting the heart volume
PCT/US1997/017898 WO1998014136A1 (en) 1996-10-02 1997-10-01 Heart volume limiting device
DE69731890T DE69731890T2 (en) 1996-10-02 1997-10-01 DEVICE FOR LIMITING THE HEART VOLUME
CA002451964A CA2451964A1 (en) 1996-10-02 1997-10-01 Heart volume limiting device
AT97909962T ATE284180T1 (en) 1996-10-02 1997-10-01 DEVICE FOR LIMITING HEART VOLUME
EP97909962A EP0930856B1 (en) 1996-10-02 1997-10-01 Heart volume limiting device
CA002267104A CA2267104C (en) 1996-10-02 1997-10-01 Heart volume limiting device
ARP970104536A AR013611A1 (en) 1996-10-02 1997-10-02 A CARDIAC REINFORCEMENT DEVICE
US09/376,812 US6165121A (en) 1996-10-02 1999-08-18 Cardiac reinforcement device
US09/483,466 US6165122A (en) 1996-10-02 2000-01-14 Cardiac reinforcement device
US09/696,651 US6375608B1 (en) 1996-10-02 2000-10-25 Cardiac reinforcement device
US10/084,806 US6544168B2 (en) 1996-10-02 2002-02-25 Cardiac reinforcement device
US10/367,346 US6893392B2 (en) 1996-10-02 2003-02-13 Cardiac reinforcement device
US10/668,460 US7163507B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,918 US7166071B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,528 US20040059181A1 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/672,226 US7261684B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/672,227 US7255674B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/794,320 US7278964B2 (en) 1996-10-02 2004-03-05 Cardiac reinforcement device
US10/810,099 US7351200B2 (en) 1996-10-02 2004-03-26 Cardiac reinforcement device
US11/469,224 US20070004962A1 (en) 1996-10-02 2006-08-31 Cardiac support device with differential compliance
US11/750,623 US20070225547A1 (en) 1996-10-02 2007-05-18 Collapsible delivery tool for cardiac support device

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US08/935,723 Continuation US6077218A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device

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US08/720,556 Expired - Lifetime US5702343A (en) 1996-10-02 1996-10-02 Cardiac reinforcement device
US08/935,723 Expired - Lifetime US6077218A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device
US08/935,440 Expired - Lifetime US6126590A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device
US09/376,812 Expired - Lifetime US6165121A (en) 1996-10-02 1999-08-18 Cardiac reinforcement device
US09/483,466 Expired - Lifetime US6165122A (en) 1996-10-02 2000-01-14 Cardiac reinforcement device
US09/696,651 Expired - Lifetime US6375608B1 (en) 1996-10-02 2000-10-25 Cardiac reinforcement device
US10/084,806 Expired - Fee Related US6544168B2 (en) 1996-10-02 2002-02-25 Cardiac reinforcement device
US10/367,346 Expired - Fee Related US6893392B2 (en) 1996-10-02 2003-02-13 Cardiac reinforcement device
US10/668,460 Expired - Fee Related US7163507B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,528 Abandoned US20040059181A1 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,918 Expired - Fee Related US7166071B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/672,227 Expired - Fee Related US7255674B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/672,226 Expired - Fee Related US7261684B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/794,320 Expired - Fee Related US7278964B2 (en) 1996-10-02 2004-03-05 Cardiac reinforcement device
US10/810,099 Expired - Fee Related US7351200B2 (en) 1996-10-02 2004-03-26 Cardiac reinforcement device
US11/750,623 Abandoned US20070225547A1 (en) 1996-10-02 2007-05-18 Collapsible delivery tool for cardiac support device

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US08/935,440 Expired - Lifetime US6126590A (en) 1996-10-02 1997-09-23 Cardiac reinforcement device
US09/376,812 Expired - Lifetime US6165121A (en) 1996-10-02 1999-08-18 Cardiac reinforcement device
US09/483,466 Expired - Lifetime US6165122A (en) 1996-10-02 2000-01-14 Cardiac reinforcement device
US09/696,651 Expired - Lifetime US6375608B1 (en) 1996-10-02 2000-10-25 Cardiac reinforcement device
US10/084,806 Expired - Fee Related US6544168B2 (en) 1996-10-02 2002-02-25 Cardiac reinforcement device
US10/367,346 Expired - Fee Related US6893392B2 (en) 1996-10-02 2003-02-13 Cardiac reinforcement device
US10/668,460 Expired - Fee Related US7163507B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,528 Abandoned US20040059181A1 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/668,918 Expired - Fee Related US7166071B2 (en) 1996-10-02 2003-09-23 Cardiac reinforcement device
US10/672,227 Expired - Fee Related US7255674B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/672,226 Expired - Fee Related US7261684B2 (en) 1996-10-02 2003-09-26 Cardiac reinforcement device
US10/794,320 Expired - Fee Related US7278964B2 (en) 1996-10-02 2004-03-05 Cardiac reinforcement device
US10/810,099 Expired - Fee Related US7351200B2 (en) 1996-10-02 2004-03-26 Cardiac reinforcement device
US11/750,623 Abandoned US20070225547A1 (en) 1996-10-02 2007-05-18 Collapsible delivery tool for cardiac support device

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AR (1) AR013611A1 (en)
AT (1) ATE284180T1 (en)
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Cited By (221)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998029041A1 (en) * 1997-01-02 1998-07-09 Myocor, Inc. Heart wall tension reduction apparatus and method
WO1998058598A1 (en) * 1997-06-21 1998-12-30 Hans Haindl Bag for at least partially enveloping a heart
WO1999044534A1 (en) * 1998-03-05 1999-09-10 The University Of Cincinnati Device and method for restructuring heart chamber geometry
US5961440A (en) * 1997-01-02 1999-10-05 Myocor, Inc. Heart wall tension reduction apparatus and method
WO1999052470A1 (en) * 1998-04-10 1999-10-21 Cardio Technologies, Inc. Cardiac remodeling and reinforcement device
WO1999056655A1 (en) * 1998-05-01 1999-11-11 Correstore, Inc. Anterior segment coronary restoration apparatus and method
WO2000002500A1 (en) 1998-07-13 2000-01-20 Acorn Cardiovascular, Inc. Cardiac disease treatment device and method
WO2000016700A1 (en) * 1998-09-21 2000-03-30 Myocor, Inc. External stress reduction device and method
US6045497A (en) * 1997-01-02 2000-04-04 Myocor, Inc. Heart wall tension reduction apparatus and method
WO2000018320A1 (en) * 1998-09-30 2000-04-06 The University Of Cincinnati Device and method for restructuring heart chamber geometry
WO2000028918A1 (en) 1998-11-18 2000-05-25 Acorn Cardiovascular, Inc. Defibrillating cardiac constraint
WO2000028912A1 (en) * 1998-11-18 2000-05-25 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion
US6077214A (en) * 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
WO2000036995A2 (en) * 1998-12-21 2000-06-29 Corset, Inc. Method and apparatus for reinforcement of the heart ventricles
US6085754A (en) * 1998-07-13 2000-07-11 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US6086527A (en) * 1998-04-02 2000-07-11 Scimed Life Systems, Inc. System for treating congestive heart failure
WO2000045735A1 (en) 1999-02-02 2000-08-10 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
US6110100A (en) * 1998-04-22 2000-08-29 Scimed Life Systems, Inc. System for stress relieving the heart muscle and for controlling heart function
US6125852A (en) * 1993-02-22 2000-10-03 Heartport, Inc. Minimally-invasive devices and methods for treatment of congestive heart failure
US6165121A (en) * 1996-10-02 2000-12-26 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6174279B1 (en) 1999-09-21 2001-01-16 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
WO2001003608A1 (en) 1999-07-07 2001-01-18 Acorn Cardiovascular, Inc. Cardiac reinforcement devices and methods
US6179791B1 (en) 1999-09-21 2001-01-30 Acorn Cardiovascular, Inc. Device for heart measurement
US6193648B1 (en) 1999-09-21 2001-02-27 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
US6221103B1 (en) 1996-01-02 2001-04-24 The University Of Cincinnati Device and method for restructuring heart chamber geometry
US6221104B1 (en) 1998-05-01 2001-04-24 Cor Restore, Inc. Anterior and interior segment cardiac restoration apparatus and method
US6234960B1 (en) * 1998-09-30 2001-05-22 A-Med Systems, Inc. Heart stabilizer apparatus
US6260552B1 (en) 1998-07-29 2001-07-17 Myocor, Inc. Transventricular implant tools and devices
WO2001050981A1 (en) 2000-01-14 2001-07-19 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
WO2001067985A1 (en) * 2000-03-10 2001-09-20 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
WO2001085061A2 (en) 2000-05-10 2001-11-15 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
WO2001091667A2 (en) 2000-05-31 2001-12-06 Cardioclasp, Inc. Devices and methods for assisting natural heart function
US6328689B1 (en) * 2000-03-23 2001-12-11 Spiration, Inc., Lung constriction apparatus and method
WO2001095832A2 (en) 2000-06-12 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
WO2001095831A2 (en) 2000-06-12 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
WO2001095830A2 (en) 2000-06-13 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6332893B1 (en) 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
US6343605B1 (en) 2000-08-08 2002-02-05 Scimed Life Systems, Inc. Percutaneous transluminal myocardial implantation device and method
WO2002013726A2 (en) 2000-08-17 2002-02-21 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
EP1078601A3 (en) * 1999-08-24 2002-05-22 Spiration, Inc. Lung volume reduction apparatus
WO2002043617A2 (en) 2000-12-01 2002-06-06 Acorn Cardiovascular, Inc. Apparatus and method for delivery of cardiac constraint jacket
US6402781B1 (en) 2000-01-31 2002-06-11 Mitralife Percutaneous mitral annuloplasty and cardiac reinforcement
US6406420B1 (en) 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6416554B1 (en) * 1999-08-24 2002-07-09 Spiration, Inc. Lung reduction apparatus and method
WO2002064035A1 (en) 2001-02-09 2002-08-22 Acorn Cardiovascular, Inc. Device for heart measurement
US20020133143A1 (en) * 2001-02-28 2002-09-19 Gregory Murphy Ventricular restoration shaping apparatus and method of use
US6463332B1 (en) 1999-09-17 2002-10-08 Core Medical, Inc. Method and system for pericardial enhancement
US20030028077A1 (en) * 1998-07-13 2003-02-06 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6537198B1 (en) 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6540659B1 (en) 2000-11-28 2003-04-01 Abiomed, Inc. Cardiac assistance systems having bi-directional pumping elements
US6544167B2 (en) 1998-05-01 2003-04-08 Correstore, Inc. Ventricular restoration patch
US6547821B1 (en) 1998-07-16 2003-04-15 Cardiothoracic Systems, Inc. Surgical procedures and devices for increasing cardiac output of the heart
US6547716B1 (en) * 2000-11-28 2003-04-15 Abiomed, Inc. Passive cardiac restraint systems having multiple layers of inflatable elements
WO2003037217A1 (en) * 2001-10-31 2003-05-08 Paracor Medical, Inc. Heart failure treatment device
US6564094B2 (en) 2000-12-22 2003-05-13 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6569082B1 (en) 1999-08-10 2003-05-27 Origin Medsystems, Inc. Apparatus and methods for cardiac restraint
WO2003043507A2 (en) 2001-11-19 2003-05-30 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US6572534B1 (en) 2000-09-14 2003-06-03 Abiomed, Inc. System and method for implanting a cardiac wrap
US6585635B1 (en) 1999-09-17 2003-07-01 Core Medical, Inc. Method and system for pericardial modification
US6587734B2 (en) 1998-11-04 2003-07-01 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
US6592619B2 (en) 1996-01-02 2003-07-15 University Of Cincinnati Heart wall actuation device for the natural heart
US20030139645A1 (en) * 2002-01-23 2003-07-24 Adelman Thomas G. Rotational freedom for a body organ
US6602182B1 (en) 2000-11-28 2003-08-05 Abiomed, Inc. Cardiac assistance systems having multiple fluid plenums
US20030149336A1 (en) * 2002-02-04 2003-08-07 Foley Frederick J. Organ manipulation assistance during surgical procedure
US20030163191A1 (en) * 1999-08-09 2003-08-28 Nikolic Serjan D. Method for improving cardiac function
US6612978B2 (en) 1999-12-22 2003-09-02 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US6616596B1 (en) 2000-11-28 2003-09-09 Abiomed, Inc. Cardiac assistance systems having multiple layers of inflatable elements
US6622730B2 (en) 2001-03-30 2003-09-23 Myocor, Inc. Device for marking and aligning positions on the heart
US20030181940A1 (en) * 2001-02-28 2003-09-25 Gregory Murphy Ventricular restoration shaping apparatus and method of use
US6626821B1 (en) 2001-05-22 2003-09-30 Abiomed, Inc. Flow-balanced cardiac wrap
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
WO2003094800A2 (en) 2002-05-10 2003-11-20 Scimed Life Systems, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US20030229260A1 (en) * 2002-06-05 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support device with tension indicator
US20030229261A1 (en) * 2002-06-06 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support devices and methods of producing same
WO2003103538A1 (en) * 2002-06-07 2003-12-18 Acorn Cardiovascular, Inc. Cardiac support device
US20040010180A1 (en) * 2002-05-16 2004-01-15 Scorvo Sean K. Cardiac assist system
US20040015039A1 (en) * 2002-07-16 2004-01-22 The University Of Cincinnati Modular power system and method for a heart wall actuation system for the natural heart
US20040015041A1 (en) * 2002-07-18 2004-01-22 The University Of Cincinnati Protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
US6682475B2 (en) 2002-06-11 2004-01-27 Acorn Cardiovascular, Inc. Tension indicator for cardiac support device and method therefore
US6685620B2 (en) 2001-09-25 2004-02-03 The Foundry Inc. Ventricular infarct assist device and methods for using it
US20040034271A1 (en) * 2002-08-19 2004-02-19 The University Of Cincinnati Heart wall actuation system for the natural heart with shape limiting elements
US6695769B2 (en) 2001-09-25 2004-02-24 The Foundry, Inc. Passive ventricular support devices and methods of using them
US20040059180A1 (en) * 2002-09-23 2004-03-25 The University Of Cincinnati Basal mounting cushion frame component to facilitate extrinsic heart wall actuation
US6723038B1 (en) 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6723041B2 (en) 2001-09-10 2004-04-20 Lilip Lau Device for treating heart failure
US20040106986A1 (en) * 2001-05-21 2004-06-03 Cid Cardiovascular Innovation Design Ab Surgical marker and an implant
US20040111101A1 (en) * 1999-08-10 2004-06-10 Chin Albert K. Endoscopic subxiphoid surgical procedures
US6749598B1 (en) 1999-01-11 2004-06-15 Flowmedica, Inc. Apparatus and methods for treating congestive heart disease
US20040138521A1 (en) * 2003-01-10 2004-07-15 Grabek James R. Myocardial constraint
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US20040176658A1 (en) * 2003-03-03 2004-09-09 Mcmurray Brian Warp knit fabrics useful for medical articles and methods of making same
US20040193138A1 (en) * 2003-03-26 2004-09-30 Levin Howard R. Method and system to treat and prevent myocardial infarct expansion
US6808483B1 (en) 2000-10-03 2004-10-26 Paul A. Spence Implantable heart assist devices and methods
US6810882B2 (en) 2001-01-30 2004-11-02 Ev3 Santa Rosa, Inc. Transluminal mitral annuloplasty
US20040243170A1 (en) * 2001-09-05 2004-12-02 Mitta Suresh Method and device for percutaneous surgical ventricular repair
US20040249408A1 (en) * 2001-09-05 2004-12-09 Chase Medical, Lp Method and device for endoscopic surgical ventricular repair
US6846296B1 (en) 2000-09-14 2005-01-25 Abiomed, Inc. Apparatus and method for detachably securing a device to a natural heart
US20050059854A1 (en) * 2003-09-16 2005-03-17 Acorn Cardiovascular, Inc. Apparatus and method for applying cardiac support device
US20050095268A1 (en) * 2000-06-12 2005-05-05 Acorn Cardiovascular, Inc. Cardiac wall tension relief with cell loss management
WO2005046520A2 (en) 2003-11-07 2005-05-26 Mayo Foundation For Medical Education And Research Device and method for treating congestive heart failure
US20050131277A1 (en) * 1997-01-02 2005-06-16 Myocor, Inc. Heart wall tension reduction apparatus and method
US20050192474A1 (en) * 2004-03-01 2005-09-01 Acorn Cardiovascular, Inc. Seam closure device and methods
WO2005097002A1 (en) 2004-04-05 2005-10-20 Edwards Lifesciences Ag Remotely adjustable coronary sinus implant
US20060004249A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Systems and methods for sizing cardiac assist device
US20060004247A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Systems and methods for assisting cardiac valve coaptation
US20060004248A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Magnetic capture and placement for cardiac assist device
US6989028B2 (en) 2000-01-31 2006-01-24 Edwards Lifesciences Ag Medical system and method for remodeling an extravascular tissue structure
US7011682B2 (en) 2000-01-31 2006-03-14 Edwards Lifesciences Ag Methods and apparatus for remodeling an extravascular tissue structure
US20060074373A1 (en) * 2000-06-12 2006-04-06 Acorn Cordiovascular, Inc. Cardiac wall tension relief device and method
US7060023B2 (en) 2001-09-25 2006-06-13 The Foundry Inc. Pericardium reinforcing devices and methods of using them
US20060135912A1 (en) * 2003-03-26 2006-06-22 G&L Consulting, Llc Biodegradable pericardia constraint system and method
US20060149348A1 (en) * 2003-11-27 2006-07-06 Bernd Vogel Compression sleeve
US20060155160A1 (en) * 2003-06-09 2006-07-13 Melvin David B Actuation mechanisms for a heart actuation device
US20060155159A1 (en) * 2003-06-09 2006-07-13 Melvin David B Power system for a heart actuation device
US20060178551A1 (en) * 2003-06-09 2006-08-10 Melvin David B Securement system for a heart actuation device
US20060189840A1 (en) * 2005-02-18 2006-08-24 Acorn Cardiovascular, Inc. Transmyocardial delivery of cardiac wall tension relief
US20060209020A1 (en) * 2005-03-18 2006-09-21 Asustek Computer Inc. Mobile phone with a virtual keyboard
US7112219B2 (en) 2002-11-12 2006-09-26 Myocor, Inc. Devices and methods for heart valve treatment
US20060217774A1 (en) * 1996-08-19 2006-09-28 Mower Morton M Cardiac contractile augmentation device and method therefor
US7122019B1 (en) 2000-11-28 2006-10-17 Flowmedica Inc. Intra-aortic renal drug delivery catheter
US7146226B2 (en) 2003-11-07 2006-12-05 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7158839B2 (en) 2003-11-07 2007-01-02 Paracor Medical, Inc. Cardiac harness for treating heart disease
US7181272B2 (en) 2002-04-22 2007-02-20 Medtronic, Inc. Cardiac restraint with electrode attachment sites
US20070043257A1 (en) * 2005-08-16 2007-02-22 The Brigham And Women's Hospital, Inc. Cardiac restraint
US7189203B2 (en) 2002-11-15 2007-03-13 Paracor Medical, Inc. Cardiac harness delivery device and method
US7214180B2 (en) 1999-08-10 2007-05-08 Origin Medsystems, Inc. Method for cardiac restraint
US7229405B2 (en) 2002-11-15 2007-06-12 Paracor Medical, Inc. Cardiac harness delivery device and method of use
US7247134B2 (en) 2002-11-12 2007-07-24 Myocor, Inc. Devices and methods for heart valve treatment
US20070208214A1 (en) * 2006-03-03 2007-09-06 Acorn Cardiovascular, Inc. Delivery tool for cardiac support device
US7282024B2 (en) 2004-01-12 2007-10-16 Paracor Medical, Inc. Cardiac harness having interconnected strands
US7288096B2 (en) 2003-01-17 2007-10-30 Origin Medsystems, Inc. Apparatus for placement of cardiac defibrillator and pacer
US7291105B2 (en) 2003-07-10 2007-11-06 Paracor Medical, Inc. Self-anchoring cardiac harness
US7293433B1 (en) 2004-03-02 2007-11-13 Atex Technologies, Inc. Warp knit fabrics useful for medical articles and methods of making same
US20080021266A1 (en) * 2006-04-19 2008-01-24 Laham Roger J Pericardial reinforcement device
US7341584B1 (en) 2003-05-30 2008-03-11 Thomas David Starkey Device and method to limit filling of the heart
US20080071134A1 (en) * 2004-09-22 2008-03-20 Shay Dubi In Vivo Device for Assisting and Improving Diastolic Ventricular Function
US20080071133A1 (en) * 2003-10-31 2008-03-20 Shay Dubi In Vivo for Improving Diastolic Ventricular Function
US20080091057A1 (en) * 2006-10-11 2008-04-17 Cardiac Pacemakers, Inc. Method and apparatus for passive left atrial support
EP1920789A1 (en) * 2006-11-11 2008-05-14 Universitätsklinikum Hamburg-Eppendorf Pouch-like construct comprising mammalian tissue
US7381182B2 (en) 2001-09-07 2008-06-03 Mardil, Inc. Method and apparatus for external heart stabilization
US7399271B2 (en) 2004-01-09 2008-07-15 Cardiokinetix, Inc. Ventricular partitioning device
US20080312492A1 (en) * 1998-10-09 2008-12-18 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence function
US20080319255A1 (en) * 2007-06-21 2008-12-25 Acorn Cardiovascular, Inc. Pericardial space imaging for cardiac support device implantation
US7485089B2 (en) 2002-09-05 2009-02-03 Paracor Medical, Inc. Cardiac harness
US7510576B2 (en) 2001-01-30 2009-03-31 Edwards Lifesciences Ag Transluminal mitral annuloplasty
US20090177028A1 (en) * 2008-01-04 2009-07-09 Anthony John White Non-blood contact cardiac compression device, for augmentation of cardiac function by timed cyclic tensioning of elastic cords in an epicardial location
US7582051B2 (en) 2005-06-10 2009-09-01 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US7587247B2 (en) 2005-08-01 2009-09-08 Paracor Medical, Inc. Cardiac harness having an optimal impedance range
US7597698B2 (en) 1999-08-10 2009-10-06 Maquet Cardiovascular Llc Apparatus and method for endoscopic encirclement of pulmonary veins for epicardial ablation
US7641608B1 (en) 2006-09-26 2010-01-05 Acorn Cardiovascular, Inc. Sectional cardiac support device and method of delivery
US7651462B2 (en) 2006-07-17 2010-01-26 Acorn Cardiovascular, Inc. Cardiac support device delivery tool with release mechanism
US7674222B2 (en) 1999-08-09 2010-03-09 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US7715918B2 (en) 2005-10-18 2010-05-11 University Of Cincinnati Muscle energy converter with smooth continuous tissue interface
US7736299B2 (en) 2002-11-15 2010-06-15 Paracor Medical, Inc. Introducer for a cardiac harness delivery
US7757692B2 (en) 2001-09-11 2010-07-20 Spiration, Inc. Removable lung reduction devices, systems, and methods
US7762943B2 (en) 2004-03-03 2010-07-27 Cardiokinetix, Inc. Inflatable ventricular partitioning device
US7766961B2 (en) 2003-06-05 2010-08-03 Angio Dynamics, Inc. Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens
US7771401B2 (en) 2006-06-08 2010-08-10 Angiodynamics, Inc. Selective renal cannulation and infusion systems and methods
US7780628B1 (en) 1999-01-11 2010-08-24 Angiodynamics, Inc. Apparatus and methods for treating congestive heart disease
US7850729B2 (en) 2002-07-18 2010-12-14 The University Of Cincinnati Deforming jacket for a heart actuation device
US7862500B2 (en) 2002-08-01 2011-01-04 Cardiokinetix, Inc. Multiple partitioning devices for heart treatment
US20110034954A1 (en) * 2007-04-13 2011-02-10 Pacesetter, Inc. Sutureless reinforcement for and method of treating a myocardial infarction
US7887477B2 (en) 1999-08-09 2011-02-15 Cardiokinetix, Inc. Method of improving cardiac function using a porous membrane
US7897086B2 (en) 2004-08-05 2011-03-01 Cardiokinetix, Inc. Method of making a laminar ventricular partitioning device
US7914503B2 (en) 2002-09-20 2011-03-29 Angio Dynamics Method and apparatus for selective material delivery via an intra-renal catheter
US20110081423A1 (en) * 2009-07-29 2011-04-07 Weldon Norman R Tissue Stabilization for Heart Failure
US7922648B1 (en) * 2006-02-14 2011-04-12 Pacesetter, Inc. Myocardial infarction patch for minimally invasive implant
US20110092761A1 (en) * 2008-02-11 2011-04-21 Corassist Cardiovascular Ltd. Ventricular function assisting devices and methods of use thereof
US7942931B2 (en) 2002-02-21 2011-05-17 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US7976454B2 (en) 2002-01-07 2011-07-12 Paracor Medical, Inc. Cardiac harness
US7993325B2 (en) 2002-09-20 2011-08-09 Angio Dynamics, Inc. Renal infusion systems and methods
US8021385B2 (en) 2002-03-20 2011-09-20 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
US8079368B2 (en) 2003-04-08 2011-12-20 Spiration, Inc. Bronchoscopic lung volume reduction method
US20110313436A1 (en) * 2003-01-27 2011-12-22 Corassist Cardiovascular Ltd. In vivo device for improving diastolic ventricular function
US8092363B2 (en) 2007-09-05 2012-01-10 Mardil, Inc. Heart band with fillable chambers to modify heart valve function
US8100821B2 (en) 2006-06-29 2012-01-24 Mardil, Inc. Low friction delivery tool for a cardiac support device
US8136230B2 (en) 2007-10-12 2012-03-20 Spiration, Inc. Valve loader method, system, and apparatus
US8192478B2 (en) 1999-08-09 2012-06-05 Cardiokinetix, Inc. System for improving cardiac function
US8192351B2 (en) 2007-08-13 2012-06-05 Paracor Medical, Inc. Medical device delivery system having integrated introducer
US8246539B2 (en) 2006-05-19 2012-08-21 Mardil, Inc. Pericardium management method for intra-pericardial surgical procedures
US8246671B2 (en) 1999-08-09 2012-08-21 Cardiokinetix, Inc. Retrievable cardiac devices
US8377114B2 (en) 1999-08-09 2013-02-19 Cardiokinetix, Inc. Sealing and filling ventricular partitioning devices to improve cardiac function
US8398537B2 (en) 2005-06-10 2013-03-19 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US8454708B2 (en) 2006-03-31 2013-06-04 Spiration, Inc. Articulable anchor
US8518011B2 (en) 2004-03-04 2013-08-27 Angiodynamics, Inc. Sheath for use in peripheral interventions
US8529430B2 (en) 2002-08-01 2013-09-10 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US8585678B2 (en) 2002-09-20 2013-11-19 Angiodynamics, Inc. Method and apparatus for intra-aortic substance delivery to a branch vessel
WO2014046065A1 (en) 2012-09-21 2014-03-27 国立大学法人大阪大学 Advanced heart failure treatment material as myocardial/cardiovascular regeneration device
US8685044B2 (en) 2001-11-28 2014-04-01 Aptus Endosystems, Inc. Systems and methods for attaching a prosthesis with a body lumen or hollow organ
US8690897B2 (en) 2001-11-28 2014-04-08 Aptus Endosystems, Inc. Devices, systems, and methods for prosthesis delivery and implantation, including the use of a fastener tool
US8790242B2 (en) 2009-10-26 2014-07-29 Cardiokinetix, Inc. Ventricular volume reduction
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
JP2014140456A (en) * 2013-01-23 2014-08-07 Olympus Corp Treatment apparatus for heart
USD717954S1 (en) 2013-10-14 2014-11-18 Mardil, Inc. Heart treatment device
US8974527B2 (en) 2003-08-08 2015-03-10 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US8986336B2 (en) 2001-10-25 2015-03-24 Spiration, Inc. Apparatus and method for deployment of a bronchial obstruction device
US9023065B2 (en) 2001-11-28 2015-05-05 Aptus Endosystems, Inc. Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ
US9051550B2 (en) 2009-04-09 2015-06-09 Arizona Board Of Regents, On Behalf Of The University Of Arizona Cellular seeding and co-culture of a three dimensional fibroblast construct
US9078660B2 (en) 2000-08-09 2015-07-14 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US20160038287A1 (en) * 2013-03-14 2016-02-11 The United States Of America As Represented By The Secretary Department Of Health And Human Services Devices and methods for treating functional tricuspid valve regurgitation
US9320503B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
US9320589B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Endovascular aneurysm repair system
US9332992B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Method for making a laminar ventricular partitioning device
US9332993B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US9370425B2 (en) 2012-10-12 2016-06-21 Mardil, Inc. Cardiac treatment system and method
US9693865B2 (en) 2013-01-09 2017-07-04 4 Tech Inc. Soft tissue depth-finding tool
US9694121B2 (en) 1999-08-09 2017-07-04 Cardiokinetix, Inc. Systems and methods for improving cardiac function
US9737403B2 (en) 2006-03-03 2017-08-22 Mardil, Inc. Self-adjusting attachment structure for a cardiac support device
US9907547B2 (en) 2014-12-02 2018-03-06 4Tech Inc. Off-center tissue anchors
US9968353B2 (en) 2001-06-04 2018-05-15 Medtronic Vascular, Inc. Catheter based fastener implantation apparatus and methods
US10058323B2 (en) 2010-01-22 2018-08-28 4 Tech Inc. Tricuspid valve repair using tension
US10064696B2 (en) 2000-08-09 2018-09-04 Edwards Lifesciences Corporation Devices and methods for delivering an endocardial device
US10098770B2 (en) 2001-11-28 2018-10-16 Medtronic Vascular, Inc. Endovascular aneurysm devices, systems, and methods
US10194905B2 (en) 2001-11-28 2019-02-05 Medtronic Vascular, Inc. Devices, systems, and methods for endovascular staple and/or prosthesis delivery and implantation
US10238491B2 (en) 2010-01-22 2019-03-26 4Tech Inc. Tricuspid valve repair using tension
US10307147B2 (en) 1999-08-09 2019-06-04 Edwards Lifesciences Corporation System for improving cardiac function by sealing a partitioning membrane within a ventricle
US10751183B2 (en) 2014-09-28 2020-08-25 Edwards Lifesciences Corporation Apparatuses for treating cardiac dysfunction
CN111921027A (en) * 2020-07-16 2020-11-13 中南大学 Flexible ventricular assist device
US10898330B2 (en) 2017-03-28 2021-01-26 Edwards Lifesciences Corporation Positioning, deploying, and retrieving implantable devices
US11109974B2 (en) * 2017-09-13 2021-09-07 Diaxamed, Llc Cardiac treatment system and method

Families Citing this family (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045771A1 (en) * 1997-01-02 2003-03-06 Schweich Cyril J. Heart wall tension reduction devices and methods
EP2111800B1 (en) 1998-07-29 2016-06-15 Edwards Lifesciences AG Transventricular implant tools and devices
US6695768B1 (en) * 1999-03-30 2004-02-24 Robert A. Levine Adjustable periventricular ring/ring like device/method for control of ischemic mitral regurgitation and congestive heart disease
US20060229491A1 (en) * 2002-08-01 2006-10-12 Cardiokinetix, Inc. Method for treating myocardial rupture
US20030187461A1 (en) * 1999-08-10 2003-10-02 Chin Albert K. Releasable guide and method for endoscopic cardiac lead placement
US20030187460A1 (en) * 1999-08-10 2003-10-02 Chin Albert K. Methods and apparatus for endoscopic cardiac surgery
US6607547B1 (en) 1999-08-25 2003-08-19 Origin Medsystems, Inc. Longitudinal dilator and method
US7526342B2 (en) * 1999-08-10 2009-04-28 Maquet Cardiovascular Llc Apparatus for endoscopic cardiac mapping and lead placement
US20060287574A1 (en) * 1999-08-25 2006-12-21 Chin Albert K Longitudinal dilator
US6365734B1 (en) * 1999-10-21 2002-04-02 Pohang University Of Science And Technology Foundation Cucurbituril derivatives, their preparation methods and uses
US6514290B1 (en) 2000-03-31 2003-02-04 Broncus Technologies, Inc. Lung elastic recoil restoring or tissue compressing device and method
ITPC20000013A1 (en) 2000-04-13 2000-07-13 Paolo Ferrazzi INTROVENTRICULAR DEVICE AND RELATED METHOD FOR THE TREATMENT AND CORRECTION OF MYOCARDIOPATHIES.
US20030023132A1 (en) * 2000-05-31 2003-01-30 Melvin David B. Cyclic device for restructuring heart chamber geometry
US6616684B1 (en) * 2000-10-06 2003-09-09 Myocor, Inc. Endovascular splinting devices and methods
US6572627B2 (en) * 2001-01-08 2003-06-03 Shlomo Gabbay System to inhibit and/or control expansion of anatomical features
US6923646B2 (en) * 2001-04-18 2005-08-02 Air Techniques, Inc. Process and apparatus for treating an exhaust stream from a dental operatory
AU2011213723B2 (en) * 2001-04-27 2015-02-05 Satterfield, Richard Prevention of myocardial infarction induced ventricular expansion and remodeling
US20040064014A1 (en) * 2001-05-31 2004-04-01 Melvin David B. Devices and methods for assisting natural heart function
US6860847B2 (en) * 2001-07-10 2005-03-01 Spiration, Inc. Constriction device viewable under X ray fluoroscopy
US20030055486A1 (en) * 2001-09-19 2003-03-20 Adams John M. Vascular reinforcement device and method
US7174896B1 (en) 2002-01-07 2007-02-13 Paracor Medical, Inc. Method and apparatus for supporting a heart
US6540666B1 (en) 2002-01-08 2003-04-01 Heart Care Associates, Llc Adaptive device for supporting cardiac function during diastolic dysfunction and method therefor
CA2483905C (en) 2002-05-09 2011-01-25 Tyco Healthcare Group Lp Endoscopic organ retractor and method of using the same
JP4468165B2 (en) * 2002-05-09 2010-05-26 タイコ ヘルスケア グループ エルピー Organ retractor and method using the same
US20030233022A1 (en) * 2002-06-12 2003-12-18 Vidlund Robert M. Devices and methods for heart valve treatment
US7814055B2 (en) * 2002-08-28 2010-10-12 Apple Inc. Method of managing a calendar and a computer system for implementing that method
JP4429167B2 (en) * 2002-10-04 2010-03-10 タイコ ヘルスケア グループ エルピー Endoscope retractor
US20050059855A1 (en) * 2002-11-15 2005-03-17 Lilip Lau Cardiac harness delivery device and method
US20070255093A1 (en) * 2002-11-15 2007-11-01 Lilip Lau Cardiac harness delivery device and method
US7198595B2 (en) * 2003-03-26 2007-04-03 Pavad Medical, Inc. Cardiac apparatus including electroactive polymer actuators and methods of using the same
US20050283042A1 (en) * 2003-03-28 2005-12-22 Steve Meyer Cardiac harness having radiopaque coating and method of use
US20040249242A1 (en) * 2003-03-28 2004-12-09 Lilip Lau Multi-panel cardiac harness
US7513867B2 (en) * 2003-07-16 2009-04-07 Kardium, Inc. Methods and devices for altering blood flow through the left ventricle
US20050013870A1 (en) * 2003-07-17 2005-01-20 Toby Freyman Decellularized extracellular matrix of conditioned body tissues and uses thereof
US20050026151A1 (en) * 2003-07-17 2005-02-03 Voyta John C. Simultaneous generation of multiple chemiluminescent signals on solid supports
US20050020871A1 (en) * 2003-07-21 2005-01-27 Piergiorgio Tozzi Artificial contractile tissue
WO2005027797A1 (en) * 2003-09-23 2005-03-31 Ersin Erek A mitral web apparatus for mitral valve insufficiencies
US20080064917A1 (en) * 2003-10-15 2008-03-13 Eli Bar Amplification-Based Cardiac Assist Device
US20050171589A1 (en) * 2003-11-07 2005-08-04 Lilip Lau Cardiac harness and method of delivery by minimally invasive access
US20070106336A1 (en) * 2003-11-07 2007-05-10 Alan Schaer Cardiac harness assembly for treating congestive heart failure and for pacing/sensing
US20050137673A1 (en) * 2003-11-07 2005-06-23 Lilip Lau Cardiac harness having electrodes and epicardial leads
US20070106359A1 (en) * 2003-11-07 2007-05-10 Alan Schaer Cardiac harness assembly for treating congestive heart failure and for pacing/sensing
US20070055091A1 (en) * 2004-12-02 2007-03-08 Lilip Lau Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US20050148814A1 (en) * 2004-01-05 2005-07-07 Fischi Michael C. Muscle function augmentation
US20050267556A1 (en) * 2004-05-28 2005-12-01 Allan Shuros Drug eluting implants to prevent cardiac apoptosis
US20060009675A1 (en) * 2004-07-08 2006-01-12 Steven Meyer Self-anchoring cardiac harness for treating the heart and for defibrillating and/or pacing/sensing
US7402134B2 (en) * 2004-07-15 2008-07-22 Micardia Corporation Magnetic devices and methods for reshaping heart anatomy
US7285087B2 (en) * 2004-07-15 2007-10-23 Micardia Corporation Shape memory devices and methods for reshaping heart anatomy
ATE552806T1 (en) * 2004-12-09 2012-04-15 Ami Gmbh GASTRIC BAND TO TREAT OBESITY
US20060129026A1 (en) * 2004-12-15 2006-06-15 Joshua Wallin Apparatus and method for mounting a cardiac harness on the heart
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7722529B2 (en) * 2004-12-28 2010-05-25 Palo Alto Investors Expandable vessel harness for treating vessel aneurysms
CA2878309C (en) * 2005-02-04 2017-11-21 Ams Research Corporation Surgical implants and related methods and systems
US7756308B2 (en) * 2005-02-07 2010-07-13 Stereotaxis, Inc. Registration of three dimensional image data to 2D-image-derived data
US20060199995A1 (en) * 2005-03-02 2006-09-07 Venkataramana Vijay Percutaneous cardiac ventricular geometry restoration device and treatment for heart failure
US7320665B2 (en) 2005-03-02 2008-01-22 Venkataramana Vijay Cardiac Ventricular Geometry Restoration Device and Treatment for Heart Failure
US20060200170A1 (en) * 2005-03-07 2006-09-07 Ernest Aranyi Specimen retrieval apparatus and method of use
US20060200169A1 (en) * 2005-03-07 2006-09-07 Kevin Sniffin Specimen retrieval apparatus and method of use
US7547310B2 (en) * 2005-03-29 2009-06-16 Tyco Healthcare Group Lp Specimen retrieval apparatus
US7670346B2 (en) * 2005-03-29 2010-03-02 Tyco Healthcare Group Lp Specimen retrieval apparatus
US20060247672A1 (en) * 2005-04-27 2006-11-02 Vidlund Robert M Devices and methods for pericardial access
US7621866B2 (en) * 2005-05-31 2009-11-24 Ethicon, Inc. Method and device for deployment of a sub-pericardial sack
US20100280493A1 (en) * 2005-06-23 2010-11-04 Asha Nayak Methods and Systems for Treating Injured Cardiac Tissue
US20070172472A1 (en) * 2005-06-23 2007-07-26 Asha Nayak Methods and Systems for Treating Injured Cardiac Tissue
US20070093748A1 (en) * 2005-06-23 2007-04-26 Medtronic Vascular, Inc. Methods and systems for treating injured cardiac tissue
US20070032696A1 (en) * 2005-07-22 2007-02-08 Sieu Duong Cardiac harness delivery device
US20070043416A1 (en) * 2005-08-19 2007-02-22 Cardiac Pacemakers, Inc. Implantable electrode array
US8875312B2 (en) * 2005-10-18 2014-11-04 Supreme Elastic Corporation Modular cut and abrasion resistant protective garment and protective garment system
US7402813B2 (en) * 2005-12-13 2008-07-22 Spectrum Dynamics Llc Lens system for nuclear medicine gamma ray camera
US20070178137A1 (en) * 2006-02-01 2007-08-02 Toby Freyman Local control of inflammation
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US20070265658A1 (en) * 2006-05-12 2007-11-15 Aga Medical Corporation Anchoring and tethering system
US20070287883A1 (en) * 2006-06-07 2007-12-13 Lilip Lau Apparatus and method for pulling a cardiac harness onto a heart
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US7877142B2 (en) * 2006-07-05 2011-01-25 Micardia Corporation Methods and systems for cardiac remodeling via resynchronization
US7837610B2 (en) 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
US20090012354A1 (en) * 2007-07-06 2009-01-08 The General Hospital Corporation D/B/A Massachusetts General Hospital System and method for intraventricular treatment
US20090048480A1 (en) * 2007-08-13 2009-02-19 Paracor Medical, Inc. Cardiac harness delivery device
EP2217153B1 (en) 2007-10-19 2021-03-03 Ancora Heart, Inc. Systems for cardiac remodeling
US20090281372A1 (en) * 2008-05-06 2009-11-12 Paracor Medical, Inc. Cardiac harness assembly for treating congestive heart failure and for defibrillation and/or pacing/sensing
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
US9370341B2 (en) 2008-10-23 2016-06-21 Covidien Lp Surgical retrieval apparatus
US20100274227A1 (en) * 2009-02-13 2010-10-28 Alexander Khairkhahan Delivery catheter handle cover
CN101554334B (en) * 2009-05-08 2011-03-23 周晓辉 Active hydraulic ventricular attaching support system
DE102009043795B4 (en) 2009-09-30 2017-10-19 AdjuCor GmbH Cardiac assist device and method for its control
WO2011041571A2 (en) 2009-10-01 2011-04-07 Kardium Inc. Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve
US8585712B2 (en) 2010-02-03 2013-11-19 Covidien Lp Surgical retrieval apparatus
US9113848B2 (en) 2010-02-03 2015-08-25 Covidien Lp Surgical retrieval apparatus
US8486087B2 (en) 2010-05-03 2013-07-16 Covidien Lp System and method for removing excised tissue
US9050066B2 (en) 2010-06-07 2015-06-09 Kardium Inc. Closing openings in anatomical tissue
US20130102835A1 (en) * 2010-06-29 2013-04-25 University Of Virginia Patent Foundation Anisotropic reinforcement and related method thereof
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
US9005215B2 (en) 2010-10-04 2015-04-14 Covidien Lp Specimen retrieval apparatus
US8777961B2 (en) 2010-10-04 2014-07-15 Covidien Lp Surgical retrieval apparatus
US8579914B2 (en) 2010-12-17 2013-11-12 Covidien Lp Specimen retrieval device
US8734464B2 (en) 2011-01-06 2014-05-27 Covidien Lp Surgical retrieval apparatus for thoracic procedures
US8696641B1 (en) * 2011-03-10 2014-04-15 Archie B. Williams, III Male incontinence containment device
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
US8795291B2 (en) 2011-04-29 2014-08-05 Covidien Lp Specimen retrieval device
EP2559410B1 (en) 2011-08-18 2013-12-25 A.M.I. Agency for Medical Innovations GmbH Device for treating obesity
US8968329B2 (en) 2011-10-19 2015-03-03 Covidien Lp Surgical retrieval apparatus for thoracic procedures
US9993229B2 (en) 2011-11-08 2018-06-12 Covidien Lp Specimen retrieval device
US8906036B2 (en) 2011-11-21 2014-12-09 Covidien Lp Surgical retrieval apparatus
US9549747B2 (en) 2012-01-23 2017-01-24 Covidien Lp Reusable surgical retrieval apparatus with disposable cartridge assembly
US9220824B2 (en) 2013-01-08 2015-12-29 AdjuCor GmbH Implanting cardiac devices
DE102013200148A1 (en) 2013-01-08 2014-07-10 AdjuCor GmbH Plug system for a cardiac assist device
DE102013200154A1 (en) * 2013-01-08 2014-07-10 AdjuCor GmbH A heart support device having a shell and first and second sheaths
DE102013200151A1 (en) 2013-01-08 2014-07-10 AdjuCor GmbH Heart support device with markings
JP6430411B2 (en) 2013-03-01 2018-11-28 コヴィディエン リミテッド パートナーシップ Sample collection device with pouch stop
US9592067B2 (en) 2013-06-14 2017-03-14 Covidien Lp Specimen retrieval device including a reusable shaft with interchangeable pouch
US9987031B2 (en) 2013-06-14 2018-06-05 Covidien Lp Specimen retrieval device including an integrated sliding grasper
CA2921042A1 (en) 2013-08-23 2015-02-26 Covidien Lp Specimen retrieval device
WO2017161080A1 (en) 2016-03-17 2017-09-21 Rugart Eric S Organ enclosures for inhibiting tumor invasion and detecting organ pathology
US10076462B2 (en) 2016-04-27 2018-09-18 Radial Medical, Inc. Adaptive compression therapy systems and methods
US10653400B2 (en) 2017-08-07 2020-05-19 Covidien Lp Specimen retrieval device
US11065051B2 (en) 2017-11-03 2021-07-20 Covidien Lp Specimen retrieval device
US10973543B2 (en) 2018-01-10 2021-04-13 Covidien Lp Dual wall tissue extraction bag
US10874386B2 (en) 2018-01-24 2020-12-29 Covidien Lp Specimen retrieval device
US11730459B2 (en) 2018-02-22 2023-08-22 Covidien Lp Specimen retrieval devices and methods
CA3093711A1 (en) * 2018-03-23 2019-09-26 Unity Health Toronto Device, method, and kit for perihepatic packing
US11083443B2 (en) 2018-04-24 2021-08-10 Covidien Lp Specimen retrieval device
US11045176B2 (en) 2018-05-18 2021-06-29 Covidien Lp Specimen retrieval device
US11134932B2 (en) 2018-08-13 2021-10-05 Covidien Lp Specimen retrieval device
US11730480B2 (en) 2018-09-14 2023-08-22 Covidien Lp Method and apparatus for accessing matter disposed within an internal body vessel
US11191559B2 (en) 2018-09-19 2021-12-07 Covidien Lp Specimen retrieval device
EP3789077B1 (en) 2019-02-26 2022-08-31 iCorNet Laboratory Co., Ltd. Cardiac support net and implantable defibrillator
US11344300B2 (en) 2019-03-26 2022-05-31 Covidien Lp Specimen capture stapler
US11172915B2 (en) 2019-04-24 2021-11-16 Covidien Lp Specimen retrieval devices with selective bag release
US11064984B2 (en) 2019-05-07 2021-07-20 Covidien Lp Specimen containment device
US11246578B2 (en) 2019-05-15 2022-02-15 Covidien Lp Tissue collection bags with inner surface pouches
US11426151B2 (en) 2019-06-04 2022-08-30 Covidien Lp Bag closure for specimen retrieval device
US11446015B2 (en) 2019-10-30 2022-09-20 Covidien Lp Specimen retrieval bag

Citations (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983863A (en) * 1975-06-02 1976-10-05 American Hospital Supply Corporation Heart support for coronary artery surgery
US4048990A (en) * 1976-09-17 1977-09-20 Goetz Robert H Heart massage apparatus
SU1009457A1 (en) * 1981-07-15 1983-04-07 Проблемная Лаборатория "Вспомогательного Кровообращения" Благовещенского Медицинского Института Artificial pericardium
US4403604A (en) * 1982-05-13 1983-09-13 Wilkinson Lawrence H Gastric pouch
US4428375A (en) * 1982-02-16 1984-01-31 Ellman Barry R Surgical bag for splenorrhaphy
JPS60203250A (en) * 1984-03-29 1985-10-14 日本ゼオン株式会社 Patch for heart operation
US4630597A (en) * 1984-04-30 1986-12-23 Adrian Kantrowitz Dynamic aortic patch for thoracic or abdominal implantation
US4690134A (en) * 1985-07-01 1987-09-01 Snyders Robert V Ventricular assist device
US4821723A (en) * 1987-02-27 1989-04-18 Intermedics Inc. Biphasic waveforms for defibrillation
JPH01145066A (en) * 1987-09-16 1989-06-07 Phillip H Evans Method and apparatus for mechanically reinforcing heart
US4878890A (en) * 1986-10-15 1989-11-07 Ethicon, Inc. Perihepatic prosthesis
US4936857A (en) * 1987-02-23 1990-06-26 Kulik Yaroslav P Prosthetic pericardium
US4957477A (en) * 1986-05-22 1990-09-18 Astra Tech Ab Heart assist jacket and method of using it
US4973300A (en) * 1989-09-22 1990-11-27 Pioneering Technologies, Inc. Cardiac sling for circumflex coronary artery surgery
US4976730A (en) * 1988-10-11 1990-12-11 Kwan Gett Clifford S Artificial pericardium
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5131905A (en) * 1990-07-16 1992-07-21 Grooters Ronald K External cardiac assist device
US5186711A (en) * 1989-03-07 1993-02-16 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US5256132A (en) * 1992-08-17 1993-10-26 Snyders Robert V Cardiac assist envelope for endoscopic application
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
US5356432A (en) * 1993-02-05 1994-10-18 C. R. Bard, Inc. Implantable mesh prosthesis and method for repairing muscle or tissue wall defects
US5383840A (en) * 1992-07-28 1995-01-24 Vascor, Inc. Biocompatible ventricular assist and arrhythmia control device including cardiac compression band-stay-pad assembly
US5385156A (en) * 1993-08-27 1995-01-31 Rose Health Care Systems Diagnostic and treatment method for cardiac rupture and apparatus for performing the same
US5429584A (en) * 1990-11-09 1995-07-04 Mcgill University Cardiac assist method and apparatus
US5507117A (en) * 1993-05-28 1996-04-16 County Line Limited Partnership, L.L.C. Tree stand
US5524633A (en) * 1991-11-25 1996-06-11 Advanced Surgical, Inc. Self-deploying isolation bag

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US393863A (en) * 1888-12-04 Sleigh
US4827932A (en) * 1987-02-27 1989-05-09 Intermedics Inc. Implantable defibrillation electrodes
DE3708248A1 (en) * 1987-03-13 1988-09-22 Herion Werke Kg 2-WAY VALVE
JP2736895B2 (en) * 1988-06-08 1998-04-02 旭光学工業株式会社 Step exposure equipment
JPH02271829A (en) 1989-04-13 1990-11-06 Tanaka Kikinzoku Kogyo Kk Electrode for deciding myocardial infarction
US5057117A (en) * 1989-04-27 1991-10-15 The Research Foundation Of State University Of New York Method and apparatus for hemostasis and compartmentalization of a bleeding internal bodily organ
US5042463A (en) * 1990-05-23 1991-08-27 Siemens-Pacesetter, Inc. Patch electrode for heart defibrillator
US5150716A (en) * 1991-01-28 1992-09-29 Emile Franssen System for diagnosis and staging of dementia by neurologic examination
US5313905A (en) * 1991-05-09 1994-05-24 Calderon Albert A Twin wing sailing yacht
US5150706A (en) * 1991-08-15 1992-09-29 Cox James L Cooling net for cardiac or transplant surgery
US5192314A (en) * 1991-12-12 1993-03-09 Daskalakis Michael K Synthetic intraventricular implants and method of inserting
CA2089999A1 (en) 1992-02-24 1993-08-25 H. Jonathan Tovey Resilient arm mesh deployer
US5352184A (en) * 1992-03-12 1994-10-04 Uresil Corporation Reservoir for enclosing and retrieving body specimens
CA2098896C (en) * 1992-06-30 2005-03-29 H. Jonathan Tovey Specimen retrieval pouch and method for use
JP2960819B2 (en) * 1992-07-29 1999-10-12 シャープ株式会社 Optical pickup device
US5290132A (en) * 1993-02-11 1994-03-01 General Motors Corporation Plastic flash screw clip arrangement
DE4406951A1 (en) * 1994-03-03 1995-09-07 Bayer Ag Superabsorbent polymers
US5507779A (en) * 1994-04-12 1996-04-16 Ventritex, Inc. Cardiac insulation for defibrillation
US5603337A (en) * 1994-12-05 1997-02-18 Jarvik; Robert Two-stage cardiomyoplasty
US5647380A (en) * 1995-06-07 1997-07-15 W. L. Gore & Associates, Inc. Method of making a left ventricular assist device
US5800528A (en) * 1995-06-13 1998-09-01 Abiomed R & D, Inc. Passive girdle for heart ventricle for therapeutic aid to patients having ventricular dilatation
US5713954A (en) * 1995-06-13 1998-02-03 Abiomed R&D, Inc. Extra cardiac ventricular assist device
DE29517393U1 (en) * 1995-11-03 1996-02-01 Hohmann Claas Dr Med Pericardial prosthesis
US5702343A (en) * 1996-10-02 1997-12-30 Acorn Medical, Inc. Cardiac reinforcement device
US6050936A (en) * 1997-01-02 2000-04-18 Myocor, Inc. Heart wall tension reduction apparatus
EP0991373B1 (en) * 1997-06-21 2004-09-15 Acorn Cardiovascular, Inc. Bag for at least partially enveloping a heart
US6042707A (en) * 1998-05-22 2000-03-28 Cvc Products, Inc. Multiple-coil electromagnet for magnetically orienting thin films

Patent Citations (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983863A (en) * 1975-06-02 1976-10-05 American Hospital Supply Corporation Heart support for coronary artery surgery
US4048990A (en) * 1976-09-17 1977-09-20 Goetz Robert H Heart massage apparatus
SU1009457A1 (en) * 1981-07-15 1983-04-07 Проблемная Лаборатория "Вспомогательного Кровообращения" Благовещенского Медицинского Института Artificial pericardium
US4428375A (en) * 1982-02-16 1984-01-31 Ellman Barry R Surgical bag for splenorrhaphy
US4403604A (en) * 1982-05-13 1983-09-13 Wilkinson Lawrence H Gastric pouch
JPS60203250A (en) * 1984-03-29 1985-10-14 日本ゼオン株式会社 Patch for heart operation
US4630597A (en) * 1984-04-30 1986-12-23 Adrian Kantrowitz Dynamic aortic patch for thoracic or abdominal implantation
US4690134A (en) * 1985-07-01 1987-09-01 Snyders Robert V Ventricular assist device
US4957477A (en) * 1986-05-22 1990-09-18 Astra Tech Ab Heart assist jacket and method of using it
US4878890A (en) * 1986-10-15 1989-11-07 Ethicon, Inc. Perihepatic prosthesis
US4936857A (en) * 1987-02-23 1990-06-26 Kulik Yaroslav P Prosthetic pericardium
US4821723A (en) * 1987-02-27 1989-04-18 Intermedics Inc. Biphasic waveforms for defibrillation
JPH01145066A (en) * 1987-09-16 1989-06-07 Phillip H Evans Method and apparatus for mechanically reinforcing heart
US4976730A (en) * 1988-10-11 1990-12-11 Kwan Gett Clifford S Artificial pericardium
US5186711A (en) * 1989-03-07 1993-02-16 Albert Einstein College Of Medicine Of Yeshiva University Hemostasis apparatus and method
US4973300A (en) * 1989-09-22 1990-11-27 Pioneering Technologies, Inc. Cardiac sling for circumflex coronary artery surgery
US5087243A (en) * 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5131905A (en) * 1990-07-16 1992-07-21 Grooters Ronald K External cardiac assist device
US5429584A (en) * 1990-11-09 1995-07-04 Mcgill University Cardiac assist method and apparatus
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
US5524633A (en) * 1991-11-25 1996-06-11 Advanced Surgical, Inc. Self-deploying isolation bag
US5383840A (en) * 1992-07-28 1995-01-24 Vascor, Inc. Biocompatible ventricular assist and arrhythmia control device including cardiac compression band-stay-pad assembly
US5256132A (en) * 1992-08-17 1993-10-26 Snyders Robert V Cardiac assist envelope for endoscopic application
US5356432A (en) * 1993-02-05 1994-10-18 C. R. Bard, Inc. Implantable mesh prosthesis and method for repairing muscle or tissue wall defects
US5356432B1 (en) * 1993-02-05 1997-02-04 Bard Inc C R Implantable mesh prosthesis and method for repairing muscle or tissue wall defects
US5507117A (en) * 1993-05-28 1996-04-16 County Line Limited Partnership, L.L.C. Tree stand
US5385156A (en) * 1993-08-27 1995-01-31 Rose Health Care Systems Diagnostic and treatment method for cardiac rupture and apparatus for performing the same

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
David A. Kass et al., "Reverse Remodeling From Cardiomyoplasty in Human Heart Failure, External Constraint Versus Active Assist", Circulation 91(9): 2314-2318 (May 1, 1995).
David A. Kass et al., Reverse Remodeling From Cardiomyoplasty in Human Heart Failure, External Constraint Versus Active Assist , Circulation 91(9): 2314 2318 (May 1, 1995). *
Howard R. Levin et al., "Reversal of Chronic Ventricular Dilation in Patients With End-Stage Cardiomyopathy by Prolonged Mechanical Unloading", Circulation 91 (11): 2717-2720 (Jun. 1, 1995).
Howard R. Levin et al., Reversal of Chronic Ventricular Dilation in Patients With End Stage Cardiomyopathy by Prolonged Mechanical Unloading , Circulation 91 (11): 2717 2720 (Jun. 1, 1995). *
Jay N. Cohn, "The Management of Chronic Heart Failure", The New Eng. J. of Med., 335(7): 490-498 (Aug. 15, 1996).
Jay N. Cohn, The Management of Chronic Heart Failure , The New Eng. J. of Med ., 335(7): 490 498 (Aug. 15, 1996). *

Cited By (534)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6125852A (en) * 1993-02-22 2000-10-03 Heartport, Inc. Minimally-invasive devices and methods for treatment of congestive heart failure
US7361191B2 (en) 1996-01-02 2008-04-22 The University Of Cincinnati Heart wall actuation device for the natural heart
US20020022880A1 (en) * 1996-01-02 2002-02-21 Melvin David B. Device and method for restructuring heart chamber geometry
US6520904B1 (en) 1996-01-02 2003-02-18 The University Of Cincinnati Device and method for restructuring heart chamber geometry
US6592619B2 (en) 1996-01-02 2003-07-15 University Of Cincinnati Heart wall actuation device for the natural heart
US6221103B1 (en) 1996-01-02 2001-04-24 The University Of Cincinnati Device and method for restructuring heart chamber geometry
US20040024286A1 (en) * 1996-01-02 2004-02-05 The University Of Cincinnati Heart wall actuation device for the natural heart
US20060217774A1 (en) * 1996-08-19 2006-09-28 Mower Morton M Cardiac contractile augmentation device and method therefor
US6165122A (en) * 1996-10-02 2000-12-26 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6165121A (en) * 1996-10-02 2000-12-26 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6375608B1 (en) * 1996-10-02 2002-04-23 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6544168B2 (en) 1996-10-02 2003-04-08 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US20030149333A1 (en) * 1996-10-02 2003-08-07 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US20040059181A1 (en) * 1996-10-02 2004-03-25 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US20040059182A1 (en) * 1996-10-02 2004-03-25 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7351200B2 (en) 1996-10-02 2008-04-01 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7278964B2 (en) 1996-10-02 2007-10-09 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7261684B2 (en) 1996-10-02 2007-08-28 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US20040171909A1 (en) * 1996-10-02 2004-09-02 Acron Cardiovascular, Inc. Cardiac reinforcement device
US7255674B2 (en) 1996-10-02 2007-08-14 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US20040181124A1 (en) * 1996-10-02 2004-09-16 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7166071B2 (en) 1996-10-02 2007-01-23 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6893392B2 (en) 1996-10-02 2005-05-17 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7163507B2 (en) 1996-10-02 2007-01-16 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US7189199B2 (en) 1997-01-02 2007-03-13 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6406420B1 (en) 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6165119A (en) * 1997-01-02 2000-12-26 Myocor, Inc. Heart wall tension reduction apparatus and method
US7695425B2 (en) 1997-01-02 2010-04-13 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US6332864B1 (en) 1997-01-02 2001-12-25 Myocor, Inc. Heart wall tension reduction apparatus
US6165120A (en) * 1997-01-02 2000-12-26 Myocor, Inc. Heart wall tension reduction apparatus and method
US20050131277A1 (en) * 1997-01-02 2005-06-16 Myocor, Inc. Heart wall tension reduction apparatus and method
US6332863B1 (en) 1997-01-02 2001-12-25 Myocor, Inc. Heart wall tension reduction kit
US6793618B2 (en) 1997-01-02 2004-09-21 Myocor, Inc. Heart wall tension reduction apparatus
US6045497A (en) * 1997-01-02 2000-04-04 Myocor, Inc. Heart wall tension reduction apparatus and method
US8267852B2 (en) 1997-01-02 2012-09-18 Edwards Lifesciences, Llc Heart wall tension reduction apparatus and method
US6050936A (en) * 1997-01-02 2000-04-18 Myocor, Inc. Heart wall tension reduction apparatus
US6755777B2 (en) 1997-01-02 2004-06-29 Myocor, Inc. Heart wall tension reduction apparatus and method
US6514194B2 (en) 1997-01-02 2003-02-04 Myocor, Inc. Heart wall tension reduction apparatus and method
US8460173B2 (en) 1997-01-02 2013-06-11 Edwards Lifesciences, Llc Heart wall tension reduction apparatus and method
WO1998029041A1 (en) * 1997-01-02 1998-07-09 Myocor, Inc. Heart wall tension reduction apparatus and method
US7883539B2 (en) 1997-01-02 2011-02-08 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
US6162168A (en) * 1997-01-02 2000-12-19 Myocor, Inc. Heart wall tension reduction apparatus
US6629921B1 (en) 1997-01-02 2003-10-07 Myocor, Inc. Heart wall tension reduction apparatus and method
US6059715A (en) * 1997-01-02 2000-05-09 Myocor, Inc. Heart wall tension reduction apparatus
US5961440A (en) * 1997-01-02 1999-10-05 Myocor, Inc. Heart wall tension reduction apparatus and method
US6589160B2 (en) 1997-01-02 2003-07-08 Myocor Inc Heart wall tension reduction apparatus
US6261222B1 (en) 1997-01-02 2001-07-17 Myocor, Inc. Heart wall tension reduction apparatus and method
US6645139B2 (en) 1997-06-21 2003-11-11 Acorn Cardiovascular Inc. Bag for at least partially enveloping a heart
US6416459B1 (en) 1997-06-21 2002-07-09 Acorn Cardiovascular Inc. Bag for at least partially enveloping a heart
WO1998058598A1 (en) * 1997-06-21 1998-12-30 Hans Haindl Bag for at least partially enveloping a heart
US8226711B2 (en) 1997-12-17 2012-07-24 Edwards Lifesciences, Llc Valve to myocardium tension members device and method
US8187323B2 (en) 1997-12-17 2012-05-29 Edwards Lifesciences, Llc Valve to myocardium tension members device and method
US6332893B1 (en) 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
WO1999044534A1 (en) * 1998-03-05 1999-09-10 The University Of Cincinnati Device and method for restructuring heart chamber geometry
AU752832B2 (en) * 1998-03-05 2002-10-03 University Of Cincinnati, The Device and method for restructuring heart chamber geometry
US6409760B1 (en) 1998-03-05 2002-06-25 University Of Cincinnati Device and method for restructuring heart chamber geometry
US6190408B1 (en) 1998-03-05 2001-02-20 The University Of Cincinnati Device and method for restructuring the heart chamber geometry
US6280377B1 (en) 1998-04-02 2001-08-28 Scimed Life Systems, Inc. System for treating congestive heart failure
US6086527A (en) * 1998-04-02 2000-07-11 Scimed Life Systems, Inc. System for treating congestive heart failure
AU758285B2 (en) * 1998-04-10 2003-03-20 Robert V. Snyders Cardiac remodeling and reinforcement device
WO1999052470A1 (en) * 1998-04-10 1999-10-21 Cardio Technologies, Inc. Cardiac remodeling and reinforcement device
US6095968A (en) * 1998-04-10 2000-08-01 Cardio Technologies, Inc. Reinforcement device
US6494825B1 (en) * 1998-04-22 2002-12-17 Scimed Life Systems, Inc. System for stress relieving the heart muscle and for controlling heart function
US6110100A (en) * 1998-04-22 2000-08-29 Scimed Life Systems, Inc. System for stress relieving the heart muscle and for controlling heart function
US6439237B1 (en) 1998-05-01 2002-08-27 Correstore, Inc. Anterior segment coronary restoration apparatus and method
US20020198603A1 (en) * 1998-05-01 2002-12-26 Correstore, Inc. Anterior segment ventricular restoration apparatus and method
US6544167B2 (en) 1998-05-01 2003-04-08 Correstore, Inc. Ventricular restoration patch
WO1999056655A1 (en) * 1998-05-01 1999-11-11 Correstore, Inc. Anterior segment coronary restoration apparatus and method
US20060258900A1 (en) * 1998-05-01 2006-11-16 Buckberg Gerald D Anterior Segment Ventricular Restoration Apparatus and Method
US20100081869A1 (en) * 1998-05-01 2010-04-01 Buckberg Gerald D Ventricular Restoration Patch
US6450171B1 (en) 1998-05-01 2002-09-17 Correstore, Inc. Anterior and inferior segment ventricular restoration apparatus and method
US7594886B2 (en) 1998-05-01 2009-09-29 Correstore Llc Method of using ventricular restoration patch
US7914438B2 (en) 1998-05-01 2011-03-29 Correstore Llc Ventricular restoration patch
US20040181126A1 (en) * 1998-05-01 2004-09-16 Buckberg Gerald D. Anterior and inferior segment ventricular restoration apparatus and method
US20030191538A1 (en) * 1998-05-01 2003-10-09 Buckberg Gerald D. Method of using ventricular restoration patch
US7056280B2 (en) 1998-05-01 2006-06-06 Correstore, Inc. Anterior segment ventricular restoration apparatus and method
US20050119520A1 (en) * 1998-05-01 2005-06-02 Buckberg Gerald D. Method of using ventricular restoration patch
US6221104B1 (en) 1998-05-01 2001-04-24 Cor Restore, Inc. Anterior and interior segment cardiac restoration apparatus and method
US7758494B2 (en) * 1998-05-01 2010-07-20 Correstore, Inc. Anterior segment ventricular restoration apparatus and method
US6024096A (en) * 1998-05-01 2000-02-15 Correstore Inc Anterior segment ventricular restoration apparatus and method
US6837247B2 (en) 1998-05-01 2005-01-04 Correstore, Inc. Method of using ventricular restoration patch
US7275546B2 (en) 1998-05-01 2007-10-02 Buckberg Gerald D Anterior and inferior segment ventricular restoration apparatus and method
US7578784B2 (en) * 1998-07-13 2009-08-25 Acorn Cardiovasculas, Inc. Cardiac support device with differential expansion
US20060235265A1 (en) * 1998-07-13 2006-10-19 Acorn Cardiovascular, Inc. Cardiac support device with anti-fibrosis coating
AU745832B2 (en) * 1998-07-13 2002-04-11 Acorn Cardiovascular, Inc. Cardiac disease treatment device and method
US6582355B2 (en) 1998-07-13 2003-06-24 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US20060111607A1 (en) * 1998-07-13 2006-05-25 Acorn Cardiovascular, Inc. Cardiac support with metallic structure
US20040181121A1 (en) * 1998-07-13 2004-09-16 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20040181123A1 (en) * 1998-07-13 2004-09-16 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6896652B2 (en) 1998-07-13 2005-05-24 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6085754A (en) * 1998-07-13 2000-07-11 Acorn Cardiovascular, Inc. Cardiac disease treatment method
US7575547B2 (en) 1998-07-13 2009-08-18 Acorn Cardiovascular, Inc. Cardiac support device with anti-fibrosis coating
US20040181122A1 (en) * 1998-07-13 2004-09-16 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7022064B2 (en) 1998-07-13 2006-04-04 Acorn Cardiovascular, Inc. Cardiac support with controlled ventricular pressure
US20030028077A1 (en) * 1998-07-13 2003-02-06 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7651461B2 (en) 1998-07-13 2010-01-26 Acorn Cardiovascular, Inc. Cardiac support with metallic structure
US7025719B2 (en) 1998-07-13 2006-04-11 Acorn Cardiovascular, Inc. Metallic cardiac support device
US6997865B2 (en) 1998-07-13 2006-02-14 Acorn Cardiovascular, Inc. Cardiac support device with anti-fibrosis lining
WO2000002500A1 (en) 1998-07-13 2000-01-20 Acorn Cardiovascular, Inc. Cardiac disease treatment device and method
US7153258B2 (en) 1998-07-13 2006-12-26 Acorn Cardiovascular, Inc. Cardiac support disease with anti-fibrosis coating
US6537203B1 (en) 1998-07-13 2003-03-25 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6547821B1 (en) 1998-07-16 2003-04-15 Cardiothoracic Systems, Inc. Surgical procedures and devices for increasing cardiac output of the heart
US7361137B2 (en) * 1998-07-16 2008-04-22 Cardiothoracic Systems, Inc. Surgical procedures and devices for increasing cardiac output of the heart
US20080161638A1 (en) * 1998-07-16 2008-07-03 Taylor Charles S Sergical procedures and devices for increasing cardiac output of the heart
US20050143620A1 (en) * 1998-07-29 2005-06-30 Myocor, Inc. Stress reduction apparatus and method
US6908424B2 (en) 1998-07-29 2005-06-21 Myocor, Inc. Stress reduction apparatus and method
US7722523B2 (en) 1998-07-29 2010-05-25 Edwards Lifesciences Llc Transventricular implant tools and devices
US6077214A (en) * 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
US6402680B2 (en) 1998-07-29 2002-06-11 Myocor, Inc. Stress reduction apparatus and method
US8439817B2 (en) 1998-07-29 2013-05-14 Edwards Lifesciences, Llc Chordae capturing methods for stress reduction
US6746471B2 (en) 1998-07-29 2004-06-08 Myocor, Inc. Transventricular implant tools and devices
US6260552B1 (en) 1998-07-29 2001-07-17 Myocor, Inc. Transventricular implant tools and devices
US6264602B1 (en) 1998-07-29 2001-07-24 Myocor, Inc. Stress reduction apparatus and method
WO2000006027A3 (en) * 1998-07-29 2001-11-08 Myocor Inc Heart stress reduction apparatus and method
US7981020B2 (en) 1998-07-29 2011-07-19 Edwards Lifesciences Llc Transventricular implant tools and devices
US6808488B2 (en) 1998-09-21 2004-10-26 Myocor, Inc. External stress reduction device and method
US6183411B1 (en) 1998-09-21 2001-02-06 Myocor, Inc. External stress reduction device and method
US6402679B1 (en) 1998-09-21 2002-06-11 Myocor, Inc. External stress reduction device and method
WO2000016700A1 (en) * 1998-09-21 2000-03-30 Myocor, Inc. External stress reduction device and method
US8579798B2 (en) 1998-09-21 2013-11-12 Edwards Lifesciences, Llc External cardiac stress reduction method
WO2000018320A1 (en) * 1998-09-30 2000-04-06 The University Of Cincinnati Device and method for restructuring heart chamber geometry
US6558319B1 (en) 1998-09-30 2003-05-06 A-Med Systems, Inc. Heart stabilizer apparatus
US6234960B1 (en) * 1998-09-30 2001-05-22 A-Med Systems, Inc. Heart stabilizer apparatus
US6685627B2 (en) 1998-10-09 2004-02-03 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US7390293B2 (en) 1998-10-09 2008-06-24 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence function
US8715156B2 (en) 1998-10-09 2014-05-06 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence function
US20080312492A1 (en) * 1998-10-09 2008-12-18 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence function
US6876887B2 (en) 1998-11-04 2005-04-05 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
US20050171590A1 (en) * 1998-11-04 2005-08-04 Acorn Cardiovascular, Inc. Cardiomyopathy treatment device with electrode therapy
US6587734B2 (en) 1998-11-04 2003-07-01 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
WO2000028912A1 (en) * 1998-11-18 2000-05-25 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion
US6370429B1 (en) 1998-11-18 2002-04-09 Acorn Cardiovascular, Inc. Defibrillating cardiac constraint
US6169922B1 (en) * 1998-11-18 2001-01-02 Acorn Cardiovascular, Inc. Defibrillating cardiac jacket with interwoven electrode grids
WO2000028918A1 (en) 1998-11-18 2000-05-25 Acorn Cardiovascular, Inc. Defibrillating cardiac constraint
US6230714B1 (en) 1998-11-18 2001-05-15 Acorn Cardiovascular, Inc. Cardiac constraint with prior venus occlusion methods
US6567699B2 (en) * 1998-11-18 2003-05-20 Acorn Cardiovascular, Inc. Defibrillating cardiac constraint
WO2000036995A3 (en) * 1998-12-21 2000-11-09 Corset Inc Method and apparatus for reinforcement of the heart ventricles
WO2000036995A2 (en) * 1998-12-21 2000-06-29 Corset, Inc. Method and apparatus for reinforcement of the heart ventricles
US6432039B1 (en) * 1998-12-21 2002-08-13 Corset, Inc. Methods and apparatus for reinforcement of the heart ventricles
US6749598B1 (en) 1999-01-11 2004-06-15 Flowmedica, Inc. Apparatus and methods for treating congestive heart disease
US7780628B1 (en) 1999-01-11 2010-08-24 Angiodynamics, Inc. Apparatus and methods for treating congestive heart disease
WO2000045735A1 (en) 1999-02-02 2000-08-10 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
US6155972A (en) * 1999-02-02 2000-12-05 Acorn Cardiovascular, Inc. Cardiac constraint jacket construction
WO2001003608A1 (en) 1999-07-07 2001-01-18 Acorn Cardiovascular, Inc. Cardiac reinforcement devices and methods
US6241654B1 (en) 1999-07-07 2001-06-05 Acorn Cardiovasculr, Inc. Cardiac reinforcement devices and methods
US9872767B2 (en) 1999-08-09 2018-01-23 Edwards Lifesciences Corporation Retrievable cardiac devices
US7674222B2 (en) 1999-08-09 2010-03-09 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US10307147B2 (en) 1999-08-09 2019-06-04 Edwards Lifesciences Corporation System for improving cardiac function by sealing a partitioning membrane within a ventricle
US6852076B2 (en) 1999-08-09 2005-02-08 Cardiokinetix, Inc. Method for improving cardiac function
US8192478B2 (en) 1999-08-09 2012-06-05 Cardiokinetix, Inc. System for improving cardiac function
US8657873B2 (en) 1999-08-09 2014-02-25 Cardiokinetix, Inc. System for improving cardiac function
US8377114B2 (en) 1999-08-09 2013-02-19 Cardiokinetix, Inc. Sealing and filling ventricular partitioning devices to improve cardiac function
US9694121B2 (en) 1999-08-09 2017-07-04 Cardiokinetix, Inc. Systems and methods for improving cardiac function
US8747454B2 (en) 1999-08-09 2014-06-10 Cardiokinetix, Inc. System for improving cardiac function
US7279007B2 (en) 1999-08-09 2007-10-09 Cardioklnetix, Inc. Method for improving cardiac function
US8257428B2 (en) 1999-08-09 2012-09-04 Cardiokinetix, Inc. System for improving cardiac function
US8246671B2 (en) 1999-08-09 2012-08-21 Cardiokinetix, Inc. Retrievable cardiac devices
US9017394B2 (en) 1999-08-09 2015-04-28 Cardiokinetix, Inc. Retrievable cardiac devices
US7887477B2 (en) 1999-08-09 2011-02-15 Cardiokinetix, Inc. Method of improving cardiac function using a porous membrane
US8672827B2 (en) 1999-08-09 2014-03-18 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US8388672B2 (en) 1999-08-09 2013-03-05 Cardiokinetix, Inc. System for improving cardiac function by sealing a partitioning membrane within a ventricle
US10307253B2 (en) 1999-08-09 2019-06-04 Edwards Lifesciences Corporation System for improving cardiac function by sealing a partitioning membrane within a ventricle
US8500795B2 (en) 1999-08-09 2013-08-06 Cardiokinetix, Inc. Retrievable devices for improving cardiac function
US7303526B2 (en) 1999-08-09 2007-12-04 Cardiokinetix, Inc. Device for improving cardiac function
US20030163191A1 (en) * 1999-08-09 2003-08-28 Nikolic Serjan D. Method for improving cardiac function
US8500790B2 (en) 1999-08-09 2013-08-06 Cardiokinetix, Inc. Retrievable cardiac devices
US20040111101A1 (en) * 1999-08-10 2004-06-10 Chin Albert K. Endoscopic subxiphoid surgical procedures
US7597698B2 (en) 1999-08-10 2009-10-06 Maquet Cardiovascular Llc Apparatus and method for endoscopic encirclement of pulmonary veins for epicardial ablation
US6569082B1 (en) 1999-08-10 2003-05-27 Origin Medsystems, Inc. Apparatus and methods for cardiac restraint
US7264587B2 (en) 1999-08-10 2007-09-04 Origin Medsystems, Inc. Endoscopic subxiphoid surgical procedures
US7214180B2 (en) 1999-08-10 2007-05-08 Origin Medsystems, Inc. Method for cardiac restraint
US6416554B1 (en) * 1999-08-24 2002-07-09 Spiration, Inc. Lung reduction apparatus and method
EP1078601A3 (en) * 1999-08-24 2002-05-22 Spiration, Inc. Lung volume reduction apparatus
US6463332B1 (en) 1999-09-17 2002-10-08 Core Medical, Inc. Method and system for pericardial enhancement
US6585635B1 (en) 1999-09-17 2003-07-01 Core Medical, Inc. Method and system for pericardial modification
US6193648B1 (en) 1999-09-21 2001-02-27 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
WO2001021070A1 (en) 1999-09-21 2001-03-29 Acorn Cardiovascular, Inc. Device for heart measurement
WO2001021099A1 (en) 1999-09-21 2001-03-29 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
WO2001021098A1 (en) 1999-09-21 2001-03-29 Acorn Cardiovascular, Inc. Cardiac constraint with draw string tensioning
US6179791B1 (en) 1999-09-21 2001-01-30 Acorn Cardiovascular, Inc. Device for heart measurement
US6174279B1 (en) 1999-09-21 2001-01-16 Acorn Cardiovascular, Inc. Cardiac constraint with tension indicator
US6702732B1 (en) 1999-12-22 2004-03-09 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US6612978B2 (en) 1999-12-22 2003-09-02 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US6663558B2 (en) 1999-12-23 2003-12-16 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US6579226B2 (en) 2000-01-14 2003-06-17 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US20060155165A1 (en) * 2000-01-14 2006-07-13 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US6293906B1 (en) 2000-01-14 2001-09-25 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US20050197528A1 (en) * 2000-01-14 2005-09-08 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US20040186342A1 (en) * 2000-01-14 2004-09-23 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
WO2001050981A1 (en) 2000-01-14 2001-07-19 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US7819797B2 (en) 2000-01-14 2010-10-26 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US7419466B2 (en) * 2000-01-14 2008-09-02 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US6881185B2 (en) 2000-01-14 2005-04-19 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US6689048B2 (en) 2000-01-14 2004-02-10 Acorn Cardiovascular, Inc. Delivery of cardiac constraint jacket
US6706065B2 (en) 2000-01-31 2004-03-16 Ev3 Santa Rosa, Inc. Endoluminal ventricular retention
US7988726B2 (en) 2000-01-31 2011-08-02 Edward Lifesciences Llc Percutaneous mitral annuloplasty with cardiac rhythm management
US6402781B1 (en) 2000-01-31 2002-06-11 Mitralife Percutaneous mitral annuloplasty and cardiac reinforcement
US6989028B2 (en) 2000-01-31 2006-01-24 Edwards Lifesciences Ag Medical system and method for remodeling an extravascular tissue structure
US6709456B2 (en) 2000-01-31 2004-03-23 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty with hemodynamic monitoring
US7507252B2 (en) 2000-01-31 2009-03-24 Edwards Lifesciences Ag Adjustable transluminal annuloplasty system
DE10103955B4 (en) * 2000-01-31 2016-07-21 Edwards Lifesciences Ag Percutaneous mitral cannulation and cardiac reinforcement
US7935146B2 (en) 2000-01-31 2011-05-03 Edwards Lifesciences Ag Percutaneous mitral annuloplasty with hemodynamic monitoring
US6537314B2 (en) 2000-01-31 2003-03-25 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty and cardiac reinforcement
US7011682B2 (en) 2000-01-31 2006-03-14 Edwards Lifesciences Ag Methods and apparatus for remodeling an extravascular tissue structure
US7296577B2 (en) 2000-01-31 2007-11-20 Edwards Lifescience Ag Transluminal mitral annuloplasty with active anchoring
WO2001067985A1 (en) * 2000-03-10 2001-09-20 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US7124493B2 (en) 2000-03-10 2006-10-24 Paracor Medical, Inc. Method of manufacturing a cardiac harness
US6612979B2 (en) 2000-03-10 2003-09-02 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US7077802B2 (en) * 2000-03-10 2006-07-18 Paracor Medical, Inc. Expandable cardiac harness for treating congestive heart failure
US7081086B2 (en) 2000-03-10 2006-07-25 Paracor Medical, Inc. Expandable cardiac harness for treating congestive heart failure
US7238152B2 (en) * 2000-03-10 2007-07-03 Paracor Medical, Inc. Self-adjusting expandable cardiac harness for treating congestive heart failure
US6602184B2 (en) 2000-03-10 2003-08-05 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US7097611B2 (en) 2000-03-10 2006-08-29 Paracor Medical, Inc. Expandable cardiac harness for treating congestive heart failure
US20040162463A1 (en) * 2000-03-10 2004-08-19 Lilip Lau Expandable cardiac harness for treating congestive heart failure
US6595912B2 (en) 2000-03-10 2003-07-22 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US7410461B2 (en) 2000-03-10 2008-08-12 Paracor Medical, Inc. Cardiac treatment apparatus
US20050102016A1 (en) * 2000-03-10 2005-05-12 Lilip Lau Expandable cardiac harness for treating congestive heart failure
US6682474B2 (en) 2000-03-10 2004-01-27 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
US7189202B2 (en) 2000-03-10 2007-03-13 Paracor Medical, Inc. Self-sizing cardiac harness for treating congestive heart failure
US7044905B2 (en) 2000-03-21 2006-05-16 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6537198B1 (en) 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US20050043745A1 (en) * 2000-03-23 2005-02-24 Alferness Clifton A. Tissue resection device, system, and method
US6790172B2 (en) 2000-03-23 2004-09-14 Spiration, Inc. Tissue resection device, system and method
US6485407B2 (en) * 2000-03-23 2002-11-26 Spiration, Inc. Tissue resection device, system and method
US6328689B1 (en) * 2000-03-23 2001-12-11 Spiration, Inc., Lung constriction apparatus and method
US7615000B2 (en) 2000-03-23 2009-11-10 Spiration, Inc. Tissue resection device, system, and method
USRE45921E1 (en) 2000-03-23 2016-03-15 Spiration, Inc. Tissue resection device, system, and method
US6908426B2 (en) 2000-05-10 2005-06-21 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
WO2001085061A2 (en) 2000-05-10 2001-11-15 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6425856B1 (en) 2000-05-10 2002-07-30 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20040133069A1 (en) * 2000-05-10 2004-07-08 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7252632B2 (en) 2000-05-10 2007-08-07 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20110196196A1 (en) * 2000-05-10 2011-08-11 Mardil, Inc. Cardiac disease treatment and device
US9005109B2 (en) * 2000-05-10 2015-04-14 Mardil, Inc. Cardiac disease treatment and device
US7938768B2 (en) 2000-05-10 2011-05-10 Mardil, Inc. Cardiac disease treatment and device
WO2001085061A3 (en) * 2000-05-10 2002-05-30 Acorn Cardiovascular Inc Cardiac disease treatment and device
WO2001091667A2 (en) 2000-05-31 2001-12-06 Cardioclasp, Inc. Devices and methods for assisting natural heart function
US20050004428A1 (en) * 2000-06-12 2005-01-06 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7618364B2 (en) 2000-06-12 2009-11-17 Acorn Cardiovascular, Inc. Cardiac wall tension relief device and method
US20060074373A1 (en) * 2000-06-12 2006-04-06 Acorn Cordiovascular, Inc. Cardiac wall tension relief device and method
WO2001095832A2 (en) 2000-06-12 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6902522B1 (en) 2000-06-12 2005-06-07 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20080125622A1 (en) * 2000-06-12 2008-05-29 Acorn Cardiovascular, Inc Cardiac wall tension relief with cell loss management
WO2001095831A2 (en) 2000-06-12 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6730016B1 (en) 2000-06-12 2004-05-04 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7326174B2 (en) 2000-06-12 2008-02-05 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20050095268A1 (en) * 2000-06-12 2005-05-05 Acorn Cardiovascular, Inc. Cardiac wall tension relief with cell loss management
US6951534B2 (en) 2000-06-13 2005-10-04 Acorn Cardiovascular, Inc. Cardiac support device
US20100185050A1 (en) * 2000-06-13 2010-07-22 Acorn Cardiovascular, Inc. Compliant cardiac support device
US20120136201A1 (en) * 2000-06-13 2012-05-31 Mardil, Inc. Cardiac support device
US6902524B2 (en) 2000-06-13 2005-06-07 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US8801598B2 (en) * 2000-06-13 2014-08-12 Mardil, Inc. Cardiac support device
US8109868B2 (en) * 2000-06-13 2012-02-07 Mardil, Inc. Cardiac support device
US20100274075A1 (en) * 2000-06-13 2010-10-28 Acorn Cardiovascular, Inc. Cardiac support device
WO2001095830A2 (en) 2000-06-13 2001-12-20 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6682476B2 (en) 2000-06-13 2004-01-27 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US20110166413A1 (en) * 2000-06-13 2011-07-07 Mardil, Inc. Compliant cardiac support device
US20050228217A1 (en) * 2000-06-13 2005-10-13 Acorn Cardiovascular, Inc. Compliant cardiac support device
US6482146B1 (en) 2000-06-13 2002-11-19 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6343605B1 (en) 2000-08-08 2002-02-05 Scimed Life Systems, Inc. Percutaneous transluminal myocardial implantation device and method
US10064696B2 (en) 2000-08-09 2018-09-04 Edwards Lifesciences Corporation Devices and methods for delivering an endocardial device
US9078660B2 (en) 2000-08-09 2015-07-14 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US7214181B2 (en) 2000-08-17 2007-05-08 Acorn Cardiovascular, Inc. Septum attached ventricular support
US20030199733A1 (en) * 2000-08-17 2003-10-23 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6572533B1 (en) 2000-08-17 2003-06-03 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
WO2002013726A2 (en) 2000-08-17 2002-02-21 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6846296B1 (en) 2000-09-14 2005-01-25 Abiomed, Inc. Apparatus and method for detachably securing a device to a natural heart
US6572534B1 (en) 2000-09-14 2003-06-03 Abiomed, Inc. System and method for implanting a cardiac wrap
US6808483B1 (en) 2000-10-03 2004-10-26 Paul A. Spence Implantable heart assist devices and methods
US20050113632A1 (en) * 2000-10-03 2005-05-26 Paul A. Spence Implantable heart assist devices and methods
US7766812B2 (en) 2000-10-06 2010-08-03 Edwards Lifesciences Llc Methods and devices for improving mitral valve function
US9198757B2 (en) 2000-10-06 2015-12-01 Edwards Lifesciences, Llc Methods and devices for improving mitral valve function
US6723038B1 (en) 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
US6547716B1 (en) * 2000-11-28 2003-04-15 Abiomed, Inc. Passive cardiac restraint systems having multiple layers of inflatable elements
US6540659B1 (en) 2000-11-28 2003-04-01 Abiomed, Inc. Cardiac assistance systems having bi-directional pumping elements
US6616596B1 (en) 2000-11-28 2003-09-09 Abiomed, Inc. Cardiac assistance systems having multiple layers of inflatable elements
US6602182B1 (en) 2000-11-28 2003-08-05 Abiomed, Inc. Cardiac assistance systems having multiple fluid plenums
US7122019B1 (en) 2000-11-28 2006-10-17 Flowmedica Inc. Intra-aortic renal drug delivery catheter
US6755779B2 (en) * 2000-12-01 2004-06-29 Acorn Cardiovascular, Inc. Apparatus and method for delivery of cardiac constraint jacket
WO2002043617A3 (en) * 2000-12-01 2002-08-15 Acorn Cardiovascular Inc Apparatus and method for delivery of cardiac constraint jacket
WO2002043617A2 (en) 2000-12-01 2002-06-06 Acorn Cardiovascular, Inc. Apparatus and method for delivery of cardiac constraint jacket
US6564094B2 (en) 2000-12-22 2003-05-13 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US6810882B2 (en) 2001-01-30 2004-11-02 Ev3 Santa Rosa, Inc. Transluminal mitral annuloplasty
US7510576B2 (en) 2001-01-30 2009-03-31 Edwards Lifesciences Ag Transluminal mitral annuloplasty
WO2002064035A1 (en) 2001-02-09 2002-08-22 Acorn Cardiovascular, Inc. Device for heart measurement
US6575921B2 (en) 2001-02-09 2003-06-10 Acorn Cardiovascular, Inc. Device for heart measurement
US20020133054A1 (en) * 2001-02-28 2002-09-19 Gregory Murphy Sizing apparatus and method for use during ventricular restoration
US6994093B2 (en) 2001-02-28 2006-02-07 Chase Medical, L.P. Ventricular restoration shaping apparatus and method of use
US6681773B2 (en) 2001-02-28 2004-01-27 Chase Medical, Inc. Kit and method for use during ventricular restoration
US6959711B2 (en) 2001-02-28 2005-11-01 Chase Medical, L.P. Kit and method for use during ventricular restoration
US20030181940A1 (en) * 2001-02-28 2003-09-25 Gregory Murphy Ventricular restoration shaping apparatus and method of use
US20020133143A1 (en) * 2001-02-28 2002-09-19 Gregory Murphy Ventricular restoration shaping apparatus and method of use
US20020133182A1 (en) * 2001-02-28 2002-09-19 Gregory Murphy Kit and method for use during ventricular restoration
US6702763B2 (en) 2001-02-28 2004-03-09 Chase Medical, L.P. Sizing apparatus and method for use during ventricular restoration
US6622730B2 (en) 2001-03-30 2003-09-23 Myocor, Inc. Device for marking and aligning positions on the heart
US20040106986A1 (en) * 2001-05-21 2004-06-03 Cid Cardiovascular Innovation Design Ab Surgical marker and an implant
US6626821B1 (en) 2001-05-22 2003-09-30 Abiomed, Inc. Flow-balanced cardiac wrap
US9968353B2 (en) 2001-06-04 2018-05-15 Medtronic Vascular, Inc. Catheter based fastener implantation apparatus and methods
US20040249408A1 (en) * 2001-09-05 2004-12-09 Chase Medical, Lp Method and device for endoscopic surgical ventricular repair
US20040243170A1 (en) * 2001-09-05 2004-12-02 Mitta Suresh Method and device for percutaneous surgical ventricular repair
US7485088B2 (en) 2001-09-05 2009-02-03 Chase Medical L.P. Method and device for percutaneous surgical ventricular repair
US8715160B2 (en) 2001-09-07 2014-05-06 Mardil, Inc. Method and apparatus for external stabilization of the heart
US9289298B2 (en) 2001-09-07 2016-03-22 Mardil, Inc. Method and apparatus for external stabilization of the heart
US8092367B2 (en) 2001-09-07 2012-01-10 Mardil, Inc. Method for external stabilization of the base of the heart
US8128553B2 (en) 2001-09-07 2012-03-06 Mardil, Inc. Method and apparatus for external stabilization of the heart
US10292821B2 (en) 2001-09-07 2019-05-21 Phoenix Cardiac Devices, Inc. Method and apparatus for external stabilization of the heart
US7381182B2 (en) 2001-09-07 2008-06-03 Mardil, Inc. Method and apparatus for external heart stabilization
US7435213B2 (en) 2001-09-10 2008-10-14 Paracor Medical, Inc. Device for treating heart failure
US7422558B2 (en) 2001-09-10 2008-09-09 Paracor Medical, Inc. Device for treating heart failure
US6723041B2 (en) 2001-09-10 2004-04-20 Lilip Lau Device for treating heart failure
US7381181B2 (en) 2001-09-10 2008-06-03 Paracor Medical, Inc. Device for treating heart failure
US8974484B2 (en) 2001-09-11 2015-03-10 Spiration, Inc. Removable lung reduction devices, systems, and methods
US8414655B2 (en) 2001-09-11 2013-04-09 Spiration, Inc. Removable lung reduction devices, systems, and methods
US7757692B2 (en) 2001-09-11 2010-07-20 Spiration, Inc. Removable lung reduction devices, systems, and methods
US7354396B2 (en) 2001-09-25 2008-04-08 The Foundry, Inc. Passive ventricular support devices and methods of using them
US6685620B2 (en) 2001-09-25 2004-02-03 The Foundry Inc. Ventricular infarct assist device and methods for using it
US20070073100A1 (en) * 2001-09-25 2007-03-29 The Foundry Inc. Pericardium reinforcing devices and methods for using them
US20090299133A1 (en) * 2001-09-25 2009-12-03 The Foundry, Llc Ventricular infarct assist device and methods for using it
US20040260144A1 (en) * 2001-09-25 2004-12-23 The Foundry, Inc. Ventricular infarct assist device and methods for using it
US7060023B2 (en) 2001-09-25 2006-06-13 The Foundry Inc. Pericardium reinforcing devices and methods of using them
US6695769B2 (en) 2001-09-25 2004-02-24 The Foundry, Inc. Passive ventricular support devices and methods of using them
US8986336B2 (en) 2001-10-25 2015-03-24 Spiration, Inc. Apparatus and method for deployment of a bronchial obstruction device
US7276021B2 (en) 2001-10-31 2007-10-02 Paracor Medical, Inc. Heart failure treatment device and method
US7404793B2 (en) 2001-10-31 2008-07-29 Paracor Medical, Inc. Heart failure treatment device and method
WO2003037217A1 (en) * 2001-10-31 2003-05-08 Paracor Medical, Inc. Heart failure treatment device
WO2003043507A2 (en) 2001-11-19 2003-05-30 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US9023065B2 (en) 2001-11-28 2015-05-05 Aptus Endosystems, Inc. Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ
US10194905B2 (en) 2001-11-28 2019-02-05 Medtronic Vascular, Inc. Devices, systems, and methods for endovascular staple and/or prosthesis delivery and implantation
US10299791B2 (en) 2001-11-28 2019-05-28 Medtronic Vascular, Inc. Endovascular aneurysm repair system
US10357230B2 (en) 2001-11-28 2019-07-23 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
US10098770B2 (en) 2001-11-28 2018-10-16 Medtronic Vascular, Inc. Endovascular aneurysm devices, systems, and methods
US9744021B2 (en) 2001-11-28 2017-08-29 Medtronic Vascular, Inc. Devices, systems, and methods for prosthesis delivery and implantation, including the use of a fastener tool
US9320503B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
US10595867B2 (en) 2001-11-28 2020-03-24 Medtronic Vascular, Inc. Systems and methods for attaching a prosthesis within a body lumen or hollow organ
US9320589B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Endovascular aneurysm repair system
US9320591B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, systems, and methods for prosthesis delivery and implantation, including the use of a fastener tool
US8685044B2 (en) 2001-11-28 2014-04-01 Aptus Endosystems, Inc. Systems and methods for attaching a prosthesis with a body lumen or hollow organ
US8690897B2 (en) 2001-11-28 2014-04-08 Aptus Endosystems, Inc. Devices, systems, and methods for prosthesis delivery and implantation, including the use of a fastener tool
US9808250B2 (en) 2001-11-28 2017-11-07 Medtronic Vascular, Inc. Systems and methods for attaching a prosthesis within a body lumen or hollow organ
US7976454B2 (en) 2002-01-07 2011-07-12 Paracor Medical, Inc. Cardiac harness
US7678145B2 (en) 2002-01-09 2010-03-16 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US8506624B2 (en) 2002-01-09 2013-08-13 Edwards Lifesciences, Llc Devices and methods for heart valve treatment
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US7077862B2 (en) 2002-01-09 2006-07-18 Myocor, Inc. Devices and methods for heart valve treatment
US8070805B2 (en) 2002-01-09 2011-12-06 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US20030139645A1 (en) * 2002-01-23 2003-07-24 Adelman Thomas G. Rotational freedom for a body organ
US20030149336A1 (en) * 2002-02-04 2003-08-07 Foley Frederick J. Organ manipulation assistance during surgical procedure
US6951533B2 (en) * 2002-02-04 2005-10-04 Iotek, Inc. Organ manipulation assistance during surgical procedure
US7942931B2 (en) 2002-02-21 2011-05-17 Spiration, Inc. Device and method for intra-bronchial provision of a therapeutic agent
US8926647B2 (en) 2002-03-20 2015-01-06 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US8177805B2 (en) 2002-03-20 2012-05-15 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US8021385B2 (en) 2002-03-20 2011-09-20 Spiration, Inc. Removable anchored lung volume reduction devices and methods
US7181272B2 (en) 2002-04-22 2007-02-20 Medtronic, Inc. Cardiac restraint with electrode attachment sites
US20050004425A1 (en) * 2002-05-10 2005-01-06 Banik Michael S. Electroactive polymer based artificial sphincters and artificial muscle patches
US7566297B2 (en) 2002-05-10 2009-07-28 Boston Scientific Scimed, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
WO2003094800A2 (en) 2002-05-10 2003-11-20 Scimed Life Systems, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US7128707B2 (en) 2002-05-10 2006-10-31 Boston Scientific Scimed, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US8100819B2 (en) 2002-05-10 2012-01-24 Boston Scientific Scimed, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US6921360B2 (en) 2002-05-10 2005-07-26 Boston Scientific Scimed. Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US6749556B2 (en) 2002-05-10 2004-06-15 Scimed Life Systems, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US20050256367A1 (en) * 2002-05-10 2005-11-17 Banik Michael S Electroactive polymer based artificial sphincters and artificial muscle patches
US20090259315A1 (en) * 2002-05-10 2009-10-15 Boston Scientific Scimed, Inc. Electroactive polymer based artificial sphincters and artificial muscle patches
US20040010180A1 (en) * 2002-05-16 2004-01-15 Scorvo Sean K. Cardiac assist system
US20030229260A1 (en) * 2002-06-05 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support device with tension indicator
US20030229261A1 (en) * 2002-06-06 2003-12-11 Acorn Cardiovascular, Inc. Cardiac support devices and methods of producing same
WO2003103538A1 (en) * 2002-06-07 2003-12-18 Acorn Cardiovascular, Inc. Cardiac support device
US6682475B2 (en) 2002-06-11 2004-01-27 Acorn Cardiovascular, Inc. Tension indicator for cardiac support device and method therefore
US20040015039A1 (en) * 2002-07-16 2004-01-22 The University Of Cincinnati Modular power system and method for a heart wall actuation system for the natural heart
US7081084B2 (en) 2002-07-16 2006-07-25 University Of Cincinnati Modular power system and method for a heart wall actuation system for the natural heart
US20040015041A1 (en) * 2002-07-18 2004-01-22 The University Of Cincinnati Protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
WO2004008941A3 (en) * 2002-07-18 2004-07-08 Univ Cincinnati A protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
WO2004008941A2 (en) * 2002-07-18 2004-01-29 The University Of Cincinnati A protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
US20060009676A1 (en) * 2002-07-18 2006-01-12 The University Of Cincinnati Protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
US7662085B2 (en) 2002-07-18 2010-02-16 Cardioenergetics, Inc. Protective sheath apparatus and method for use with a heart wall actuation system for the natural heart
US7850729B2 (en) 2002-07-18 2010-12-14 The University Of Cincinnati Deforming jacket for a heart actuation device
US9592123B2 (en) 2002-08-01 2017-03-14 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US8529430B2 (en) 2002-08-01 2013-09-10 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US7862500B2 (en) 2002-08-01 2011-01-04 Cardiokinetix, Inc. Multiple partitioning devices for heart treatment
US8827892B2 (en) 2002-08-01 2014-09-09 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US20050250976A1 (en) * 2002-08-19 2005-11-10 The University Of Cincinnati Heart wall actuation system for the natural heart with shape limiting elements
US6988982B2 (en) 2002-08-19 2006-01-24 Cardioenergetics Heart wall actuation system for the natural heart with shape limiting elements
US20040034271A1 (en) * 2002-08-19 2004-02-19 The University Of Cincinnati Heart wall actuation system for the natural heart with shape limiting elements
US7485089B2 (en) 2002-09-05 2009-02-03 Paracor Medical, Inc. Cardiac harness
US7993325B2 (en) 2002-09-20 2011-08-09 Angio Dynamics, Inc. Renal infusion systems and methods
US7914503B2 (en) 2002-09-20 2011-03-29 Angio Dynamics Method and apparatus for selective material delivery via an intra-renal catheter
US8585678B2 (en) 2002-09-20 2013-11-19 Angiodynamics, Inc. Method and apparatus for intra-aortic substance delivery to a branch vessel
US8012121B2 (en) 2002-09-20 2011-09-06 Angiodynamics, Inc. Method and apparatus for selective material delivery via an intra-renal catheter
US20040059180A1 (en) * 2002-09-23 2004-03-25 The University Of Cincinnati Basal mounting cushion frame component to facilitate extrinsic heart wall actuation
US7112219B2 (en) 2002-11-12 2006-09-26 Myocor, Inc. Devices and methods for heart valve treatment
US7247134B2 (en) 2002-11-12 2007-07-24 Myocor, Inc. Devices and methods for heart valve treatment
US7666224B2 (en) 2002-11-12 2010-02-23 Edwards Lifesciences Llc Devices and methods for heart valve treatment
US7189203B2 (en) 2002-11-15 2007-03-13 Paracor Medical, Inc. Cardiac harness delivery device and method
US7338435B2 (en) 2002-11-15 2008-03-04 Paracor Medical, Inc. Cardiac harness delivery device and method
US7572219B2 (en) 2002-11-15 2009-08-11 Paracor Medical, Inc. Cardiac harness delivery device and method
US7736299B2 (en) 2002-11-15 2010-06-15 Paracor Medical, Inc. Introducer for a cardiac harness delivery
US7361139B2 (en) 2002-11-15 2008-04-22 Paracor Medical, Inc. Cardiac harness delivery device and method
US7229405B2 (en) 2002-11-15 2007-06-12 Paracor Medical, Inc. Cardiac harness delivery device and method of use
US7500946B2 (en) 2002-11-15 2009-03-10 Paracor Medical, Inc. Cardiac harness delivery device and method
US20040138521A1 (en) * 2003-01-10 2004-07-15 Grabek James R. Myocardial constraint
US7288096B2 (en) 2003-01-17 2007-10-30 Origin Medsystems, Inc. Apparatus for placement of cardiac defibrillator and pacer
US20110313436A1 (en) * 2003-01-27 2011-12-22 Corassist Cardiovascular Ltd. In vivo device for improving diastolic ventricular function
US20040176658A1 (en) * 2003-03-03 2004-09-09 Mcmurray Brian Warp knit fabrics useful for medical articles and methods of making same
US20040193138A1 (en) * 2003-03-26 2004-09-30 Levin Howard R. Method and system to treat and prevent myocardial infarct expansion
US20060135912A1 (en) * 2003-03-26 2006-06-22 G&L Consulting, Llc Biodegradable pericardia constraint system and method
US7883500B2 (en) 2003-03-26 2011-02-08 G&L Consulting, Llc Method and system to treat and prevent myocardial infarct expansion
US8079368B2 (en) 2003-04-08 2011-12-20 Spiration, Inc. Bronchoscopic lung volume reduction method
US7341584B1 (en) 2003-05-30 2008-03-11 Thomas David Starkey Device and method to limit filling of the heart
US7766961B2 (en) 2003-06-05 2010-08-03 Angio Dynamics, Inc. Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens
US20060178551A1 (en) * 2003-06-09 2006-08-10 Melvin David B Securement system for a heart actuation device
US7658705B2 (en) 2003-06-09 2010-02-09 Cardioenergetics, Inc. Actuation mechanisms for a heart actuation device
US20060155160A1 (en) * 2003-06-09 2006-07-13 Melvin David B Actuation mechanisms for a heart actuation device
US7753837B2 (en) 2003-06-09 2010-07-13 The University Of Cincinnati Power system for a heart actuation device
US20060155159A1 (en) * 2003-06-09 2006-07-13 Melvin David B Power system for a heart actuation device
US7291105B2 (en) 2003-07-10 2007-11-06 Paracor Medical, Inc. Self-anchoring cardiac harness
US9622752B2 (en) 2003-08-08 2017-04-18 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US8974527B2 (en) 2003-08-08 2015-03-10 Spiration, Inc. Bronchoscopic repair of air leaks in a lung
US7235042B2 (en) 2003-09-16 2007-06-26 Acorn Cardiovascular, Inc. Apparatus and method for applying cardiac support device
US20050059854A1 (en) * 2003-09-16 2005-03-17 Acorn Cardiovascular, Inc. Apparatus and method for applying cardiac support device
US7824325B2 (en) * 2003-10-31 2010-11-02 Corassist Cardiovascular Ltd. In vivo for improving diastolic ventricular function
US20080071133A1 (en) * 2003-10-31 2008-03-20 Shay Dubi In Vivo for Improving Diastolic Ventricular Function
US7225036B2 (en) 2003-11-07 2007-05-29 Paracor Medical, Inc Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7155295B2 (en) 2003-11-07 2006-12-26 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7146226B2 (en) 2003-11-07 2006-12-05 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7187984B2 (en) 2003-11-07 2007-03-06 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7164952B2 (en) 2003-11-07 2007-01-16 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7158839B2 (en) 2003-11-07 2007-01-02 Paracor Medical, Inc. Cardiac harness for treating heart disease
US7149588B2 (en) 2003-11-07 2006-12-12 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
WO2005046520A2 (en) 2003-11-07 2005-05-26 Mayo Foundation For Medical Education And Research Device and method for treating congestive heart failure
US20060149348A1 (en) * 2003-11-27 2006-07-06 Bernd Vogel Compression sleeve
US8388616B2 (en) * 2003-11-27 2013-03-05 Endosmart Gesellschaft Für Medizintechnik MbH Compression sleeve
US7399271B2 (en) 2004-01-09 2008-07-15 Cardiokinetix, Inc. Ventricular partitioning device
US7282024B2 (en) 2004-01-12 2007-10-16 Paracor Medical, Inc. Cardiac harness having interconnected strands
US20050192474A1 (en) * 2004-03-01 2005-09-01 Acorn Cardiovascular, Inc. Seam closure device and methods
US7297104B2 (en) 2004-03-01 2007-11-20 John Vanden Hoek Seam closure device and methods
US7293433B1 (en) 2004-03-02 2007-11-13 Atex Technologies, Inc. Warp knit fabrics useful for medical articles and methods of making same
US7762943B2 (en) 2004-03-03 2010-07-27 Cardiokinetix, Inc. Inflatable ventricular partitioning device
US7976455B2 (en) 2004-03-03 2011-07-12 Cardiokinetix, Inc. Inflatable ventricular partitioning device
US8518011B2 (en) 2004-03-04 2013-08-27 Angiodynamics, Inc. Sheath for use in peripheral interventions
WO2005097002A1 (en) 2004-04-05 2005-10-20 Edwards Lifesciences Ag Remotely adjustable coronary sinus implant
US20060004247A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Systems and methods for assisting cardiac valve coaptation
US7601117B2 (en) * 2004-06-30 2009-10-13 Ethicon, Inc. Systems and methods for assisting cardiac valve coaptation
US7731650B2 (en) 2004-06-30 2010-06-08 Ethicon, Inc. Magnetic capture and placement for cardiac assist device
US20060004248A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Magnetic capture and placement for cardiac assist device
US20060004249A1 (en) * 2004-06-30 2006-01-05 Ethicon Incorporated Systems and methods for sizing cardiac assist device
US7897086B2 (en) 2004-08-05 2011-03-01 Cardiokinetix, Inc. Method of making a laminar ventricular partitioning device
US9332992B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Method for making a laminar ventricular partitioning device
US9332993B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US20080071134A1 (en) * 2004-09-22 2008-03-20 Shay Dubi In Vivo Device for Assisting and Improving Diastolic Ventricular Function
US8636642B2 (en) 2004-09-22 2014-01-28 Corassist Cardiovascular Ltd. In vivo device for assisting and improving diastolic ventricular function
US20060189840A1 (en) * 2005-02-18 2006-08-24 Acorn Cardiovascular, Inc. Transmyocardial delivery of cardiac wall tension relief
US20060209020A1 (en) * 2005-03-18 2006-09-21 Asustek Computer Inc. Mobile phone with a virtual keyboard
US8398537B2 (en) 2005-06-10 2013-03-19 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US7582051B2 (en) 2005-06-10 2009-09-01 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US7587247B2 (en) 2005-08-01 2009-09-08 Paracor Medical, Inc. Cardiac harness having an optimal impedance range
US20070043257A1 (en) * 2005-08-16 2007-02-22 The Brigham And Women's Hospital, Inc. Cardiac restraint
US7715918B2 (en) 2005-10-18 2010-05-11 University Of Cincinnati Muscle energy converter with smooth continuous tissue interface
US7922648B1 (en) * 2006-02-14 2011-04-12 Pacesetter, Inc. Myocardial infarction patch for minimally invasive implant
US20070208214A1 (en) * 2006-03-03 2007-09-06 Acorn Cardiovascular, Inc. Delivery tool for cardiac support device
US8870744B2 (en) 2006-03-03 2014-10-28 Mardil, Inc. Cardiac support device delivery tool with independently movable arms
US10806580B2 (en) 2006-03-03 2020-10-20 Mardil, Inc. Self-adjusting attachment structure for a cardiac support device
US9737403B2 (en) 2006-03-03 2017-08-22 Mardil, Inc. Self-adjusting attachment structure for a cardiac support device
US7727142B2 (en) 2006-03-03 2010-06-01 Acorn Cardiovascular, Inc. Delivery tool for cardiac support device
US20100268019A1 (en) * 2006-03-03 2010-10-21 Acorn Cardiovascular, Inc. Cadiac support device delivery tool with independently movable arms
US8454708B2 (en) 2006-03-31 2013-06-04 Spiration, Inc. Articulable anchor
US8647392B2 (en) 2006-03-31 2014-02-11 Spiration, Inc. Articulable anchor
US9198669B2 (en) 2006-03-31 2015-12-01 Spiration, Inc. Articulable anchor
US20080021266A1 (en) * 2006-04-19 2008-01-24 Laham Roger J Pericardial reinforcement device
US9259318B2 (en) 2006-04-19 2016-02-16 Beth Israel Deaconess Medical Center Pericardial reinforcement device
US8246539B2 (en) 2006-05-19 2012-08-21 Mardil, Inc. Pericardium management method for intra-pericardial surgical procedures
US7771401B2 (en) 2006-06-08 2010-08-10 Angiodynamics, Inc. Selective renal cannulation and infusion systems and methods
US8100821B2 (en) 2006-06-29 2012-01-24 Mardil, Inc. Low friction delivery tool for a cardiac support device
US9737404B2 (en) 2006-07-17 2017-08-22 Mardil, Inc. Cardiac support device delivery tool with release mechanism
US8617051B2 (en) 2006-07-17 2013-12-31 Mardil, Inc. Cardiac support device delivery tool with release mechanism
US7651462B2 (en) 2006-07-17 2010-01-26 Acorn Cardiovascular, Inc. Cardiac support device delivery tool with release mechanism
US10307252B2 (en) 2006-07-17 2019-06-04 Mardil, Inc. Cardiac support device delivery tool with release mechanism
US7641608B1 (en) 2006-09-26 2010-01-05 Acorn Cardiovascular, Inc. Sectional cardiac support device and method of delivery
US20080091057A1 (en) * 2006-10-11 2008-04-17 Cardiac Pacemakers, Inc. Method and apparatus for passive left atrial support
EP1920789A1 (en) * 2006-11-11 2008-05-14 Universitätsklinikum Hamburg-Eppendorf Pouch-like construct comprising mammalian tissue
WO2008058917A1 (en) * 2006-11-11 2008-05-22 Universitätsklinikum Hamburg-Eppendorf Pouch-like construct for preventing heart distension
US10500051B2 (en) 2006-11-11 2019-12-10 Universitatsklinikum Hamburg-Eppendorf Pouch-like construct for preventing heart distension
US20100167373A1 (en) * 2006-11-11 2010-07-01 Universitatsklinikum Hamburg-Eppendorf Pouch-Like Construct for Preventing Heart Distension
US20110034954A1 (en) * 2007-04-13 2011-02-10 Pacesetter, Inc. Sutureless reinforcement for and method of treating a myocardial infarction
US8718746B2 (en) 2007-06-21 2014-05-06 Mardil, Inc. Pericardial space imaging for cardiac support device implantation
US10159781B2 (en) 2007-06-21 2018-12-25 Mardil, Inc. Pericardial space imaging for cardiac support device implantation
US20080319255A1 (en) * 2007-06-21 2008-12-25 Acorn Cardiovascular, Inc. Pericardial space imaging for cardiac support device implantation
US8192351B2 (en) 2007-08-13 2012-06-05 Paracor Medical, Inc. Medical device delivery system having integrated introducer
US8092363B2 (en) 2007-09-05 2012-01-10 Mardil, Inc. Heart band with fillable chambers to modify heart valve function
USRE46927E1 (en) 2007-09-05 2018-07-03 Mardil, Inc. Heart band with fillable chambers to modify heart valve function
US8136230B2 (en) 2007-10-12 2012-03-20 Spiration, Inc. Valve loader method, system, and apparatus
US8043301B2 (en) 2007-10-12 2011-10-25 Spiration, Inc. Valve loader method, system, and apparatus
US9326873B2 (en) 2007-10-12 2016-05-03 Spiration, Inc. Valve loader method, system, and apparatus
US20090177028A1 (en) * 2008-01-04 2009-07-09 Anthony John White Non-blood contact cardiac compression device, for augmentation of cardiac function by timed cyclic tensioning of elastic cords in an epicardial location
US8523755B2 (en) * 2008-02-11 2013-09-03 Corassist Cardiovascular Ltd. Ventricular function assisting devices and methods of use thereof
US20110092761A1 (en) * 2008-02-11 2011-04-21 Corassist Cardiovascular Ltd. Ventricular function assisting devices and methods of use thereof
US11345894B2 (en) 2009-04-09 2022-05-31 Arizona Board Of Regents On Behalf Of The University Of Arizona Cellular seeding and co-culture of a three dimensional fibroblast construct
US9976123B2 (en) 2009-04-09 2018-05-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Cellular seeding and co-culture of a three dimensional fibroblast construct
US9051550B2 (en) 2009-04-09 2015-06-09 Arizona Board Of Regents, On Behalf Of The University Of Arizona Cellular seeding and co-culture of a three dimensional fibroblast construct
US9044570B2 (en) 2009-07-29 2015-06-02 Tangio, Inc. Medical devices to facilitate tissue stabilization for heart failure
US8496911B2 (en) 2009-07-29 2013-07-30 Vatrix CHF, Inc. Tissue stabilization for heart failure
US20110081423A1 (en) * 2009-07-29 2011-04-07 Weldon Norman R Tissue Stabilization for Heart Failure
US9039597B2 (en) 2009-10-26 2015-05-26 Cardiokinetix, Inc. Ventricular volume reduction
US8790242B2 (en) 2009-10-26 2014-07-29 Cardiokinetix, Inc. Ventricular volume reduction
US10028835B2 (en) 2009-10-26 2018-07-24 Edwards Lifesciences Corporation Ventricular volume reduction
US9364327B2 (en) 2009-10-26 2016-06-14 Cardiokinetix, Inc. Ventricular volume reduction
US10238491B2 (en) 2010-01-22 2019-03-26 4Tech Inc. Tricuspid valve repair using tension
US10058323B2 (en) 2010-01-22 2018-08-28 4 Tech Inc. Tricuspid valve repair using tension
US10433963B2 (en) 2010-01-22 2019-10-08 4Tech Inc. Tissue anchor and delivery tool
US8795241B2 (en) 2011-05-13 2014-08-05 Spiration, Inc. Deployment catheter
WO2014046065A1 (en) 2012-09-21 2014-03-27 国立大学法人大阪大学 Advanced heart failure treatment material as myocardial/cardiovascular regeneration device
US9597436B2 (en) 2012-09-21 2017-03-21 Osaka University Advanced heart failure treatment material as myocardial/cardiovascular regeneration device
US9421101B2 (en) 2012-10-12 2016-08-23 Mardil, Inc. Cardiac treatment system
US9421102B2 (en) 2012-10-12 2016-08-23 Mardil, Inc. Cardiac treatment system and method
US11517437B2 (en) 2012-10-12 2022-12-06 Diaxamed, Llc Cardiac treatment system
US11406500B2 (en) 2012-10-12 2022-08-09 Diaxamed, Llc Cardiac treatment system and method
US9844437B2 (en) 2012-10-12 2017-12-19 Mardil, Inc. Cardiac treatment system and method
US9370425B2 (en) 2012-10-12 2016-06-21 Mardil, Inc. Cardiac treatment system and method
US10064723B2 (en) 2012-10-12 2018-09-04 Mardil, Inc. Cardiac treatment system and method
US10405981B2 (en) 2012-10-12 2019-09-10 Mardil, Inc. Cardiac treatment system
US10420644B2 (en) 2012-10-12 2019-09-24 Mardil, Inc. Cardiac treatment system and method
US9693865B2 (en) 2013-01-09 2017-07-04 4 Tech Inc. Soft tissue depth-finding tool
US10449050B2 (en) 2013-01-09 2019-10-22 4 Tech Inc. Soft tissue depth-finding tool
EP2949274A4 (en) * 2013-01-23 2016-11-02 Olympus Corp Heart treatment device
JP2014140456A (en) * 2013-01-23 2014-08-07 Olympus Corp Treatment apparatus for heart
US20160038287A1 (en) * 2013-03-14 2016-02-11 The United States Of America As Represented By The Secretary Department Of Health And Human Services Devices and methods for treating functional tricuspid valve regurgitation
US9987135B2 (en) * 2013-03-14 2018-06-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Devices and methods for treating functional tricuspid valve regurgitation
USD717954S1 (en) 2013-10-14 2014-11-18 Mardil, Inc. Heart treatment device
US10751183B2 (en) 2014-09-28 2020-08-25 Edwards Lifesciences Corporation Apparatuses for treating cardiac dysfunction
US11690720B2 (en) 2014-09-28 2023-07-04 Edwards Lifesciences Corporation Systems and methods for treating cardiac dysfunction
US9907547B2 (en) 2014-12-02 2018-03-06 4Tech Inc. Off-center tissue anchors
US10898330B2 (en) 2017-03-28 2021-01-26 Edwards Lifesciences Corporation Positioning, deploying, and retrieving implantable devices
US11109974B2 (en) * 2017-09-13 2021-09-07 Diaxamed, Llc Cardiac treatment system and method
CN111921027B (en) * 2020-07-16 2022-02-22 中南大学 Flexible ventricular assist device
CN111921027A (en) * 2020-07-16 2020-11-13 中南大学 Flexible ventricular assist device

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