US6564101B1 - Electrical system for weight loss and laparoscopic implanation thereof - Google Patents
Electrical system for weight loss and laparoscopic implanation thereof Download PDFInfo
- Publication number
- US6564101B1 US6564101B1 US09/601,585 US60158500A US6564101B1 US 6564101 B1 US6564101 B1 US 6564101B1 US 60158500 A US60158500 A US 60158500A US 6564101 B1 US6564101 B1 US 6564101B1
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- Prior art keywords
- controller
- stomach
- electrical
- individual
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
Definitions
- the present invention relates generally to the field of weight loss devices and more particular to the field of electrical devices employed in the treatment of seriously overweight human beings.
- the treatment of obesity has taken many different forms. Among these is the use of prescription or non-prescription drugs or other ingestible preparations designed to suppress the appetite or to induce satiety.
- Another type of treatment comprises dietary menus selected to reduce caloric intake, often in combination with a regimen of exercise.
- the treatment of obesity has included more radical techniques such as stapling or re-sectioning of the stomach or wiring the jaws shut.
- 5,540,730 discloses an apparatus and method of treating motility disorders by selectively stimulating a patient's vagus nerve to modulate electrical activity of the nerve and to thereby cause a selective release or suppression of excitatory or inhibitory transmitters
- One embodiment employs the manual or automatic activation of an implanted device for selective modulation.
- none of the aforementioned devices is totally satisfactory for effective treatment of eating disorders.
- the present invention is directed to an electrical system to directly stimulate the stomach wall to create a sensation of satiety since normally distended “full stomach” stretch receptors of the stomach wall send the message of being full or satiated. More particularly, the present invention relies upon the use of implanted leads, similar to heart pacemaker leads, to directly stimulate the stretch receptors generally found in the wall of the upper portion, or fundus, of the stomach.
- the electrical stimulator leads are generally implanted using open or laparoscopic techniques and/or by endoscopic techniques with local anesthesia, thus making the effective utilization of the device of the present invention far easier and less burdensome to the patient than with the extensive major surgical procedures required using other known techniques.
- a method for controlling the body weight of seriously overweight individuals which utilizes the system taught is also disclosed.
- FIG. 1 is a schematic representation of an electrical system of the invention.
- FIG. 2 is another schematic representation of the electrical system of the invention showing the leads implanted on the fundus of the stomach.
- FIG. 1 is a schematic representation of one embodiment of the weight control system of the invention.
- An electrical signal generator/controller, or gastric pacer, 10 has two or more connecting wires 12 , each one of which wires 12 terminates in an attachment lead 14 .
- the number of connecting wires 12 and attachments leads 14 is variable and will depend upon various conditions and circumstances, such as the size of an individual's stomach and the degree to which the individual's appetite is to be suppressed. In its simplest form two leads (minimum) will be implanted on or in the stomach wall.
- Pacer 10 may have conventional circuitry designed to generate low voltage, direct electrical pulses in the range of from about 50 millivolts to 10 volts, an amperage of from about 10 to 500 amps, a programmable pulse width of from about 0.1 to 10 msec, and a duration of from about 10 seconds to about 180 minutes, with possible use of constant output or ramped output stimulation.
- pacer 10 Preferably pacer 10 generates an electrical signal of from about 50 millivolts to about 5 volts, an amperage of from about 10 to 500 amps, and a pulse width of from about 0.1 to 1.0 msec for from about 10 seconds to about 120 minutes or more or substantially continuous low voltage stimulation with varying periodicity, in any case as a patient's specific physiology, anatomy, and/or psychology would require.
- Pacer 10 will preferably have a timing mechanism that will allow the timing and duration of the pulses to be varied or regulated as intended.
- pacer 10 could be programmed to generate pulses of about 500 millivolts, an amperage of about 50 amps, and a pulse width of about 1 msec over 30 to 120 minutes for 2 or 3 preset times of the day.
- pacer 10 could be designed to provide an electronic electric pulse “on demand”, that is, when activated by the individual and/or gastric wall contraction activated by hunger.
- an electronic electric pulse “on demand” that is, when activated by the individual and/or gastric wall contraction activated by hunger.
- there are effectively six parameters for the electrical signal namely, voltage, amperage, pulse width, ramp, duration and periodicity.
- Pacer 10 can also have a single pulse function.
- pacer 10 is located exterior to the patient on a halter or other supporting structure.
- pacer 10 could be implantable subcutaneously or within muscle sheaths.
- pacer 10 could comprise a timer for periods of programmable stimulations during a 24 hour period, i.e., daily stimulations of the stretch receptors of the stomach, for the duration of the period of stimulation necessary to give the subject the feeling of satiety which may vary among subjects.
- Gastric pacers 10 may be clipped on a patient's belt, or implanted under the skin or muscle of abdominal area during the procedure. Such pacers, not unlike cardiac pacers, can be adjusted to the patient's needs by pacing system analyzers or pacemaker pulse monitors.
- a hand-held device (not shown) which, when positioned over the skin where pacer 10 is placed under skin or muscle, would have the capacity to effect changes in several parameters by radio frequency programming (i.e., changes in amperage, voltage, pulse width, frequency/min and periodicity/24 hr and ramping).
- radio frequency programming i.e., changes in amperage, voltage, pulse width, frequency/min and periodicity/24 hr and ramping.
- the source of the electrical power for pacer 10 is preferably one or more batteries to be located within the pacer.
- the pulse (gastric stimulation) generators would have batteries which could be replaceable or rechargeable.
- pacer 10 could be electrically connected to a transformer or other power source, which may also be controlled by a transmitter with radio frequency 16 .
- hand-held device or another external device may have the ability to recharge pacer 10 .
- the implantable leads are shown attached to the exterior wall of the stomach 16 in an area known as the fundus, or upper stomach wall.
- This area of the stomach is preferred since it is rich in stretch receptors.
- the leads can be implanted using anyone of a number of techniques, such as, for example, conventional surgery through a standard incision or laparoscopic surgery or under a local anesthetic. Obviously laparoscopic surgery would be preferred due to reduced trauma to the patient, potential complications, less hospital time, and overall less complications.
- Generator/controller 10 After implantation the generator/controller is activated, and stimulating electrical signals are sent to the leads, thereby effecting the stretch receptors located in the fundus of the stomach wall.
- Generator/controller 10 can be manually operated in an on/off mode or may be programmed to automatically generate an electrical signal over a period of time either in an intermittent or a continuous fashion.
- generator/controller 10 will be provided with means to program the device to allow it to generate electronic pulses at predetermined intervals. Similarly it is contemplated that the pulse generator/controller will be provided with means to program the device to allow it to generate electrical signals of varying intensities at various intervals over a predetermined time interval.
- An adult male dog was fitted with a system according to the invention.
- Two implantable leads were implanted to the fundus of the dog's stomach.
- the implantable leads were connected by standard insulated copper wires to a generator/controller comprising a standard timing/pulsing controlled device.
- a 9V battery provided sufficient electrical charge.
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/601,585 US6564101B1 (en) | 1998-02-02 | 1999-02-02 | Electrical system for weight loss and laparoscopic implanation thereof |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7342198P | 1998-02-02 | 1998-02-02 | |
PCT/US1999/002249 WO1999038563A1 (en) | 1998-02-02 | 1999-02-02 | Electrical system for weight loss and laparoscopic implantation thereof |
US09/601,585 US6564101B1 (en) | 1998-02-02 | 1999-02-02 | Electrical system for weight loss and laparoscopic implanation thereof |
Publications (1)
Publication Number | Publication Date |
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US6564101B1 true US6564101B1 (en) | 2003-05-13 |
Family
ID=22113597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/601,585 Expired - Lifetime US6564101B1 (en) | 1998-02-02 | 1999-02-02 | Electrical system for weight loss and laparoscopic implanation thereof |
Country Status (3)
Country | Link |
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US (1) | US6564101B1 (en) |
AU (1) | AU2492699A (en) |
WO (1) | WO1999038563A1 (en) |
Cited By (85)
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US20030018367A1 (en) * | 2001-07-23 | 2003-01-23 | Dilorenzo Daniel John | Method and apparatus for neuromodulation and phsyiologic modulation for the treatment of metabolic and neuropsychiatric disease |
US20030060857A1 (en) * | 2000-09-27 | 2003-03-27 | Perrson Bruce J. | Electrode designs and methods of use for cardiovascular reflex control devices |
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US20040010303A1 (en) * | 2001-09-26 | 2004-01-15 | Cvrx, Inc. | Electrode structures and methods for their use in cardiovascular reflex control |
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