WO1989011303A1 - System for infusing a liquid into a blood vessel in particular of a human being - Google Patents

System for infusing a liquid into a blood vessel in particular of a human being Download PDF

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Publication number
WO1989011303A1
WO1989011303A1 PCT/FR1989/000234 FR8900234W WO8911303A1 WO 1989011303 A1 WO1989011303 A1 WO 1989011303A1 FR 8900234 W FR8900234 W FR 8900234W WO 8911303 A1 WO8911303 A1 WO 8911303A1
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WO
WIPO (PCT)
Prior art keywords
housing
piston
container
liquid
aforementioned
Prior art date
Application number
PCT/FR1989/000234
Other languages
French (fr)
Inventor
Jacques Adolphe Paul Soudant
Jean-Philippe René CHAUVEL
Original Assignee
Jacques Adolphe Paul Soudant
Chauvel Jean Philippe Rene
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jacques Adolphe Paul Soudant, Chauvel Jean Philippe Rene filed Critical Jacques Adolphe Paul Soudant
Publication of WO1989011303A1 publication Critical patent/WO1989011303A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags

Definitions

  • the invention relates to a system for infusing a liquid into a blood path, in particular a human being, of the type comprising a container containing said liquid, which is connected by a hose to the person under infusion, and means intended imparting to the liquid to be introduced into the blood path a predetermined pressure greater than the pressure prevailing inside said path.
  • the container is suspended at a predetermined height from a bracket mounted on a carriage which is movable on the ground, the person on an infusion being connected to the container by said flexible hose.
  • the height of the container is generally chosen so that it is at a distance of 130 cm above the point where the infusion needle enters the bloodstream. It is the column of liquid corresponding to this height which creates the perfusion pressure.
  • This known system has the major drawback of having a bulky structure which makes the movements of the person under perfusion inconvenient if not impossible in certain cases.
  • the object of the present invention is to propose a system of the type described above which is easily transportable by the person on an infusion.
  • the system according to the invention is characterized in that at least the side wall of the container is made of a flexible material and has an axially compressible configuration, the container is placed in a portable case by the person under infusion, by taking support at its end before leaving the liquid on a support wall of the housing and by its rear end closed on an axially movable surface in the housing, under the effect of a pusher device of said surface, in the direction of axial compression of the container, to drive the liquid from it.
  • the pusher device comprises spring means in the prestressed initial state which is supported by one end at the bottom of the housing and by its other end on a piston mounted axially movable in the housing and the surface opposite to the bearing surface of the spring forms the aforementioned movable surface and in that the system comprises means for adjusting the flow rate of the liquid expelled from the container when the spring is released.
  • the pusher device comprises a cartridge filled with a pressurized gas forming a source of gas spreading in the housing at a substantially constant pressure and acting on a piston mounted axially movable in the housing and whose surface opposite to that exposed to the gas constitutes the aforementioned mobile surface.
  • FIG. 1 is a view in axial section of a first embodiment of a system according to the present invention:
  • Figure 2 is a sectional view along line II-II of Figure 1;
  • Figures 3 and 4 are views in axial section, with cutaway, of two variants of the embodiment according to Figure 1;
  • Figure 5 is an axial sectional view of a second embodiment of the invention.
  • the system forming a first embodiment of the invention and shown in Figure 1 comprises a housing 1 of generally cylindrical shape closed at one end by a front wall 2 pierced in its center with an orifice 3 and capable of being closed at its other end by a hollow cylindrical member 4 which has on its external cylindrical surface a thread allowing its screwing in the end of the housing provided for this purpose with an internal thread.
  • a piston 5 is mounted axially mobile in the housing 1 and divides the internal space into two chambers of variable volume 6 and 7.
  • the chamber 6 delimited between the front wall 2 and the piston 5 houses a container 8 of generally cylindrical shape axially compressible under the effect of the displacement of the piston 5.
  • the cylindrical wall 9 of the container advantageously has an accordion configuration.
  • the container contains the infusion liquid to be discharged from the container into the bloodstream of a recipient, via a flexible tube indicated at 10 which extends inside the container through a stopper. closure 11 of the container engaged in the orifice 3 of the wall 2.
  • the chamber 7 which is delimited between the piston 5 and the closing member 4 houses a helical spring 13 which bears at one end on the bottom of the member hollow 4 and by its other end on the corresponding front surface of the piston 5.
  • the spring 13 occupies its compressed position shown .
  • the latter moves to its position shown in phantom, thereby deforming in the manner shown the cylindrical wall 9 in accordion of the container 5, which causes the liquid to flow back out of the container 8 into the pipe 10.
  • such a device essentially comprises two parallel friction rods 15 and 16 which have a substantially rectangular cross section and are in mutual friction contact by one of their malls.
  • the two rods are engaged in a groove 18 formed in the cylindrical peripheral surface of the housing 1.
  • the groove 18 extends parallel to the axis of the housing.
  • the strip 16 rests on the bottom of the groove 18 while being axially oriented in the latter. It is fixed to the cylindrical surface of the piston 5 by a fixing means 19 of any suitable nature.
  • the rod 16 is thus axially movable in the groove 18 while being driven by the piston 5.
  • the rod 17 is fixed on an element 21 for closing the groove 18.
  • This element is pivotally mounted around an axis 22 parallel to the groove and is lockable in its covering position of the groove 18 by means of rapid fixing means 23 of any suitable nature.
  • a layer 20 of an elastically compressible material has been interposed in the example shown between the friction element 17 and the closing element 21.
  • the length of the movable friction rod 16 is slightly greater than the length of the stroke of the piston 5 so that it still remains in contact with the fixed friction rod 17 over a small part of its length as indicated in the Figure 1 in broken lines, when the piston 5 occupies its end position of the rebound stroke.
  • the housing 1 is equipped with two devices 14 intended to keep the flow rate of the container 8 constant. These devices are located diametrically opposite so as to prevent the piston from jamming under the effect of the spring force 13.
  • Figure 3 shows another embodiment of the device 14.
  • the housing has an axial peripheral channel 25 through which the pipe 10 extends axially.
  • the latter is made of an elastically deformable material such as a plastic material.
  • the radially outer surface 26 of the channel 25 is inclined at a predetermined angle relative to the axis of the housing 1.
  • the channel 25 communicates with the internal space of the housing 1 by an axial slot 27.
  • This device comprises at least one roller 29, advantageously several, as in the example shown, which are freely rotatable around axes perpendicular to the longitudinal direction of the channel 25 in a support 30 which is integral with the periphery of the piston 5 and extends through the slot 27.
  • these rollers 29 are located in such a way-inside the channel 25 that the pipe 10 is engaged between the cylindrical peripheral rolling surfaces of the rollers 29 and the inclined surface 26 of the groove 25.
  • the pipe 10 In the starting position of the piston 5 , which is shown in Figure 3, the pipe 10 is highly elastically compressed, that is to say crushed and has a minimum flow section. It is easily understood that during the displacement of the piston 5 under the effect of the spring 13 in the direction of the front wall 2 of the housing 1, due to the inclination of the surface 26, the degree of crushing decreases and the cross section of flow increases.
  • the flow rate of the liquid discharged from the container 8 through the pipe 10 can be kept constant.
  • the device 28 could be in the form of a carriage provided with a number of rollers 29 juxtaposed over a length corresponding to the length of the friction rod 16 in the figure 1.
  • the surface 26 of the groove 25 extends parallel to the axis of the housing over a length corresponding to the length of the fixed friction rod 17 of FIG. 1.
  • the pipe 10 does not undergo a deformation of its cross section by the rollers 29 as a function of the displacement of the piston 5 only over a length which depends on way substantially linear displacement of the piston.
  • FIG. 5 shows a second embodiment of the system according to the invention in which the pusher device of the piston 5 is essentially formed by a cartridge 30 filled for example with pressurized air.
  • the cartridge 30 is capable of being secured to the removable closing member of the housing 1 produced in the form of a cap 31 which can be screwed onto the housing 1.
  • the cartridge has at its end opposite the piston 5 an orifice shown diagrammatically at 32 through which the pressurized air can gradually escape.
  • a pressure can be established in the space 33 between the cartridge and the piston 5 of a value suitable for pushing the piston 5 in the direction of the axial compression of the container 8.
  • the housing 1 is provided with a device 34 for regulating the pressure.
  • the device 34 whose dimensions are exaggerated for the sake of greater clarity of the representation comprises a chamber 35 which communicates with the space 33 through a channel 36 which passes through the wall of the housing 1 and is closable by a valve 37 pushed back into its closed position by a spring 38, the restoring force of which can be adjusted using an adjusting screw 39 in the external wall of the chamber 35.
  • the pressure in the chamber 33 which causes the valve 37 to open can be adjusted. It is easy to understand that the device 34 makes it possible to maintain inside the chamber 33 a pressure whose upper limit is determined by the spring 38.
  • a second device 40 for adjusting the lower pressure in the space 33 is provided on the front wall 2 of the housing.
  • This device allows a variation in the cross-section of flow of the liquid from the flexible pipe 10. It could comprise an adjustment screw 41 or be of any other suitable and known material.
  • the pressure thus kept constant will be chosen so as to obtain that the flow rate of liquid discharged from the container 8 through the pipe 10 has the desired value.
  • the cartridge 30 forming the source of the pressurized air can be produced so as to be easily refillable by equipping it, for example, with a valve device known per se, such as for example used for inflatable tires.
  • the container 8 can be produced in any other suitable known manner. It only matters that it is axially compressible.
  • any other suitable pusher device can be used to print on the piston its compression stroke of the container. One could also consider removing the piston by giving the bottom of the container sufficient rigidity so that it can replace the piston.
  • the device for maintaining constant the flow rate of the liquid discharged from the container 8 can also be produced in any other known known manner suitable for example for varying the hydraulic resistance of the pipe 10 as a function of the displacement of the piston 5 to thereby compensate for the variation in the force of the piston plunger.
  • the two adjustment devices 34, 40 for pressure in space 33 could be replaced by a regulator of the known type which would equip the outlet orifice of the cartridge.
  • the housing 1 will advantageously be made of a light material, for example by molding, to reduce its weight as much as possible. It could be provided with a strap to be easily portable for example at the waist by the person on an infusion. Thus it can move easily without being particularly hampered by the infusion system that it carries on it.
  • the dimensions of the housing depend on the volume of the container and the pusher device. They will be relatively small. For example, the diameter of the case could be of the order of 5 to 10 cm while the length could have a value of the order of 15 to 20 cm. Furthermore, it is also possible to associate with the piston 5 a movable index element making it possible to view the position of the piston relative to the housing 1.

Abstract

In the system disclosed, at least the side wall (9) of the container (8) is made of a flexible material and has an axially compressible configuration. The container (8) is placed in a housing (1) which can be carried by the person under infusion. The front end of the container for the outlet of the liquid rests on a support wall (2) of the housing (1) and its closed rear end rests on a surface (5) which moves axially in the housing (1) under the action of a pushing device (13) of said surface (5) in the direction of axial compression of the container, in order to evacuate the liquid from the latter. The invention is useful in the field of medicine.

Description

"Système pour faire une perfusion d'un liquide dans une voie sanguine notamment d'un être humain." "System for making an infusion of a liquid into a blood path, in particular of a human being."
L'invention concerne un système pour faire une perfusion d'un liquide dans une voie sanguine notamment d'un être humain, du type comprenant un récipient contenant ledit liquide, qui est relié par un tuyau à la personne sous perfusion, et des moyens destinés à conférer au liquide à introduire dans la voie sanguine une pression prédéterminée supérieure à la pression régnant à l'intérieur de ladite voie.The invention relates to a system for infusing a liquid into a blood path, in particular a human being, of the type comprising a container containing said liquid, which is connected by a hose to the person under infusion, and means intended imparting to the liquid to be introduced into the blood path a predetermined pressure greater than the pressure prevailing inside said path.
Dans des systèmes connus de ce type, le récipient est suspendu à une hauteur prédéterminée à une potence montée sur un chariot qui est mobile sur le sol, la personne sous perfusion étant reliée au récipient par ledit tuyau flexible. La hauteur du récipient est choisie généralement de façon qu'elle se trouve à une distance de 130 cm au-dessus de l'endroit où l'aiguille de perfusion pénètre dans la voie sanguine. C'est la colonne de liquide correspondant à cette hauteur qui crée la pression de perfusion.In known systems of this type, the container is suspended at a predetermined height from a bracket mounted on a carriage which is movable on the ground, the person on an infusion being connected to the container by said flexible hose. The height of the container is generally chosen so that it is at a distance of 130 cm above the point where the infusion needle enters the bloodstream. It is the column of liquid corresponding to this height which creates the perfusion pressure.
Ce système connu présente l'inconvénient majeur d'avoir une structure encombrante ce qui rend les déplacements de la personne sous perfusion peu commodes sinon impossibles dans certains cas.This known system has the major drawback of having a bulky structure which makes the movements of the person under perfusion inconvenient if not impossible in certain cases.
La présente invention a pour but de proposer un système de type décrit plus haut qui est facilement transportable par la personne sous perfusion.The object of the present invention is to propose a system of the type described above which is easily transportable by the person on an infusion.
Pour atteindre ce but, le système selon l'invention est caractérisé en ce qu'au moins la paroi latérale du récipient est réalisée en un matériau souple et présente une configuration axialement compressible, le récipient est placé dans un boîtier portable par la personne sous perfusion, en prenant appui par son extrémité avant de sortir du liquide sur une paroi d'appui du boîtier et par son extrémité arrière fermée sur une surface axialement mobile dans le boîtier, sous l'effet d'un dispositif poussoir de ladite surface, dans la direction de compression axiale du récipient, pour chasser le liquide de celle-ci.To achieve this goal, the system according to the invention is characterized in that at least the side wall of the container is made of a flexible material and has an axially compressible configuration, the container is placed in a portable case by the person under infusion, by taking support at its end before leaving the liquid on a support wall of the housing and by its rear end closed on an axially movable surface in the housing, under the effect of a pusher device of said surface, in the direction of axial compression of the container, to drive the liquid from it.
Selon une caractéristique avantageuse de l'invention, le dispositif poussoir comporte des moyens de ressort à l'état initial précontraint qui prend appui par une extrémité au fond du boîtier et par son autre extrémité sur un piston monté axialement mobile dans le boîtier et dont la surface opposée à la surface d'appui du ressort forme la surface mobile précitée et en ce que le système comprend des moyens de réglage du débit du liquide chassé du récipient lors de la détente du ressort.According to an advantageous characteristic of the invention, the pusher device comprises spring means in the prestressed initial state which is supported by one end at the bottom of the housing and by its other end on a piston mounted axially movable in the housing and the surface opposite to the bearing surface of the spring forms the aforementioned movable surface and in that the system comprises means for adjusting the flow rate of the liquid expelled from the container when the spring is released.
Selon une caractéristique de l'invention, le dispositif poussoir comprend une cartouche remplie d'un gaz sous pression formant une source de gaz se répandant dans le boîtier à une pression sensiblement constante et agissant sur un piston monté axialement mobile dans le boîtier et dont la surface opposée à celle exposée au gaz constitue la surface mobile précitée.According to a characteristic of the invention, the pusher device comprises a cartridge filled with a pressurized gas forming a source of gas spreading in the housing at a substantially constant pressure and acting on a piston mounted axially movable in the housing and whose surface opposite to that exposed to the gas constitutes the aforementioned mobile surface.
L'invention sera mieux comprise, et d'autres buts, caractéristiques, détails et avantages de celle-ci apparaîtront plus clairement au cours de la description explicative qui va suivre faite en référence aux dessins schématiques annexés donnés uniquement à titre d'exemple illustrant deux modes de réalisation de l'invention, et dans lesquels :The invention will be better understood, and other objects, characteristics, details and advantages thereof will appear more clearly during the explanatory description which follows, made with reference to the appended schematic drawings given solely by way of example illustrating two embodiments of the invention, and in which:
La figure 1 est une vue en coupe axiale d'un premier mode de réalisation d'un système selon la présente invention : La figure 2 est une vue en coupe selon la ligne II-II de la figure 1 ;FIG. 1 is a view in axial section of a first embodiment of a system according to the present invention: Figure 2 is a sectional view along line II-II of Figure 1;
Les figures 3 et 4 sont des vues en coupe axiale, avec arrachement, de deux variantes du mode de réalisation selon la figure 1 ; etFigures 3 and 4 are views in axial section, with cutaway, of two variants of the embodiment according to Figure 1; and
La figure 5 est une vue en coupe axiale d'un deuxième mode de réalisation de l'invention.Figure 5 is an axial sectional view of a second embodiment of the invention.
Le système formant un premier mode de réalisation de l'invention et représenté à la figure 1 comprend un boîtier 1 de forme générale cylindrique fermé à une extrémité par une paroi frontale 2 percée dans son centre d'un orifice 3 et susceptible d'être fermé à son autre extrémité par un organe creux cylindrique 4 qui présente sur sa surface cylindrique externe un filetage permettant son vissage dans l'extrémité du boîtier pourvu à cette fin d'un filetage interne. Un piston 5 est monté axialement mobile dans le boîtier 1 et divise l'espace interne en deux chambres de volume variable 6 et 7. La chambre 6 délimitée entre la paroi frontale 2 et le piston 5 loge un récipient 8 de forme générale cylindrique axialement compressible sous l'effet du déplacement du piston 5. Pour assurer cette compressibilité axiale, la paroi cylindrique 9 du récipient présente avantageusement une configuration en accordéon. Le récipient contient le liquide de perfusion devant être refoulé du récipient dans la voie sanguine d'une personne réceptrice, par l'intermédiaire d'un tuyau flexible indiqué en 10 qui s'étend à l'intérieur du récipient en traversant un bouchon d'obturation 11 du récipient engagé dans l'orifice 3 de la paroi 2.The system forming a first embodiment of the invention and shown in Figure 1 comprises a housing 1 of generally cylindrical shape closed at one end by a front wall 2 pierced in its center with an orifice 3 and capable of being closed at its other end by a hollow cylindrical member 4 which has on its external cylindrical surface a thread allowing its screwing in the end of the housing provided for this purpose with an internal thread. A piston 5 is mounted axially mobile in the housing 1 and divides the internal space into two chambers of variable volume 6 and 7. The chamber 6 delimited between the front wall 2 and the piston 5 houses a container 8 of generally cylindrical shape axially compressible under the effect of the displacement of the piston 5. To ensure this axial compressibility, the cylindrical wall 9 of the container advantageously has an accordion configuration. The container contains the infusion liquid to be discharged from the container into the bloodstream of a recipient, via a flexible tube indicated at 10 which extends inside the container through a stopper. closure 11 of the container engaged in the orifice 3 of the wall 2.
La chambre 7 qui est délimitée entre le piston 5 et l'organe de fermeture 4 loge un ressort hélicoïdal 13 qui prend appui à une extrémité sur le fond de l'organe creux 4 et par son autre extrémité sur la surface frontale correspondante du piston 5. Lorsque le piston occupe la position représentée en traits pleins sur la figure 1 et l'organe 4 est vissé dans le boîtier 1, le ressort 13 occupe sa position comprimée représentée. Sous l'effet de la force de pression qu'exerce ainsi le ressort sur le piston 5, ce dernier se déplace jusqu'à sa position représentée en traits mixtes en déformant ainsi de la manière représentée la paroi cylindrique 9 en accordéon du récipient 5, ce qui provoque le refoulement du liquide hors du récipient 8 dans le tuyau 10.The chamber 7 which is delimited between the piston 5 and the closing member 4 houses a helical spring 13 which bears at one end on the bottom of the member hollow 4 and by its other end on the corresponding front surface of the piston 5. When the piston occupies the position shown in solid lines in FIG. 1 and the member 4 is screwed into the housing 1, the spring 13 occupies its compressed position shown . Under the effect of the pressure force thus exerted by the spring on the piston 5, the latter moves to its position shown in phantom, thereby deforming in the manner shown the cylindrical wall 9 in accordion of the container 5, which causes the liquid to flow back out of the container 8 into the pipe 10.
Etant donné que la force exercée par le ressort 13 sur le piston 5 diminue sensiblement linéairement avec la longueur de la course de détente du ressort, le système selon l'invention est pourvu de deux dispositifs 14 permettant de maintenir sensiblement constant le débit du liquide refoulé dans le tuyau 10. Dans sa version de réalisation représentée aux figures 1 et 2, un tel dispositif comprend essentiellement deux baguettes parallèles de friction 15 et 16 qui présentent une section transversale sensiblement rectangulaire et sont en contact de friction mutuel par l'une de leurs grandes surfaces. Les deux baguettes sont engagées dans une rainure 18 pratiquée dans la surface périphérique cylindrique du boîtier 1. La rainure 18 s'étend parallèlement à l'axe du boîtier. La baguette 16 repose sur le fond de la rainure 18 en étant axialement orientée dans celle-ci. Elle est fixée à la surface cylindrique du piston 5 par un moyen de fixation 19 de toute nature appropriée. La baguette 16 est ainsi mobile axialement dans la rainure 18 en étant entraînée par le piston 5. La baguette 17 est fixée sur un élément 21 de fermeture de la rainure 18. Cet élément est monté pivotant autour d'un axe 22 parallèle à la rainure et est verroulllable dans sa position de recouvrement de la rainure 18 à l'aide de moyens de fixation rapide 23 de toute nature appropriée. Pour assurer un contact pressé entre les baguettes 16 et 17, on a interposé dans l'exemple représenté entre l'élément de friction 17 et l'élément de fermeture 21 une couche 20 en un matériau élastiquement compressible. La longueur de la baguette de friction mobile 16 est légèrement supérieure à la longueur de la course du piston 5 de façon qu'elle reste encore en contact avec la baguette de friction fixe 17 sur une faible partie de sa longueur comme cela est indiqué à la figure 1 en traits interrompus, lorsque le piston 5 occupe sa position de fin de course de détente.Since the force exerted by the spring 13 on the piston 5 decreases appreciably linearly with the length of the rebound stroke of the spring, the system according to the invention is provided with two devices 14 making it possible to maintain the flow of the discharged liquid substantially constant in the pipe 10. In the embodiment shown in Figures 1 and 2, such a device essentially comprises two parallel friction rods 15 and 16 which have a substantially rectangular cross section and are in mutual friction contact by one of their malls. The two rods are engaged in a groove 18 formed in the cylindrical peripheral surface of the housing 1. The groove 18 extends parallel to the axis of the housing. The strip 16 rests on the bottom of the groove 18 while being axially oriented in the latter. It is fixed to the cylindrical surface of the piston 5 by a fixing means 19 of any suitable nature. The rod 16 is thus axially movable in the groove 18 while being driven by the piston 5. The rod 17 is fixed on an element 21 for closing the groove 18. This element is pivotally mounted around an axis 22 parallel to the groove and is lockable in its covering position of the groove 18 by means of rapid fixing means 23 of any suitable nature. To ensure pressed contact between the strips 16 and 17, a layer 20 of an elastically compressible material has been interposed in the example shown between the friction element 17 and the closing element 21. The length of the movable friction rod 16 is slightly greater than the length of the stroke of the piston 5 so that it still remains in contact with the fixed friction rod 17 over a small part of its length as indicated in the Figure 1 in broken lines, when the piston 5 occupies its end position of the rebound stroke.
Au lieu d'articuler l'élément de fermeture 21 au boîtier 1, on pourrait également tout simplement la réaliser sous forme d'une baguette amovible susceptible d'être fixée sur le boîtier par exemple par des vis.Instead of hinging the closing element 21 to the housing 1, it could also simply be produced in the form of a removable rod capable of being fixed to the housing, for example by screws.
Dans l'exemple représenté, le boîtier 1 est équipé de deux dispositifs 14 destinés à maintenir constant le débit du récipient 8. Ces dispositifs sont situés diamétralement opposés de façon à empêcher un effet de coincement du piston sous l'effet de la force du ressort 13.In the example shown, the housing 1 is equipped with two devices 14 intended to keep the flow rate of the container 8 constant. These devices are located diametrically opposite so as to prevent the piston from jamming under the effect of the spring force 13.
La figure 3 montre une autre version de réalisation du dispositif 14. De façon similaire, le boîtier comporte un canal périphérique axial 25 à travers lequel s'étend axialement le tuyau 10. Celui-ci est réalisé en un matériau élastiquement déformable tel qu'un matériau plastique. La surface radialement extérieure 26 du canal 25 est inclinée selon un angle prédéterminé par rapport à l'axe du boîtier 1. Le canal 25 communique avec l'espace interne du boîtier 1 par une fente axiale 27. En 28 on reconnaît sur la figure 3 un dispositif de variation de la section d'écoulement du tuyau 10. Ce dispositif comprend au moins un galet 29, avantageusement plusieurs comme dans l'exemple représenté, qui sont montés librement rotatifs autour d'axes perpendiculaires à la direction longitudinale du canal 25 dans un support 30 qui est solidaire de la périphérie du piston 5 et s'étend à travers la fente 27. ces galets 29 sont situés de telle manière-à l'intérieur du canal 25 que le tuyau 10 soit en prise entre les surfaces périphériques cylindriques de roulement des galets 29 et la surface 26 inclinée de la rainure 25. Dans la position de départ du piston 5, qui est représentée à la figure 3, le tuyau 10 est fortement élastiquement comprimé, c'est-à-dire écrasé et présente une section d'écoulement minimale. On comprend aisément que lors du déplacement du piston 5 sous l'effet du ressort 13 en direction de la paroi frontale 2 du boîtier 1, en raison de l'inclinaison de la surface 26, le degré d'écrasement diminue et la section d'écoulement augmente. Par un choix approprié de l'inclinaison de la surface 26 et de façon générale, en conférant à celle-ci une allure appropriée, le débit du liquide refoulé du récipient 8 à travers le tuyau 10 peut être maintenu constant.Figure 3 shows another embodiment of the device 14. Similarly, the housing has an axial peripheral channel 25 through which the pipe 10 extends axially. The latter is made of an elastically deformable material such as a plastic material. The radially outer surface 26 of the channel 25 is inclined at a predetermined angle relative to the axis of the housing 1. The channel 25 communicates with the internal space of the housing 1 by an axial slot 27. At 28 we recognize in Figure 3 a device for varying the flow section of the pipe 10. This device comprises at least one roller 29, advantageously several, as in the example shown, which are freely rotatable around axes perpendicular to the longitudinal direction of the channel 25 in a support 30 which is integral with the periphery of the piston 5 and extends through the slot 27. these rollers 29 are located in such a way-inside the channel 25 that the pipe 10 is engaged between the cylindrical peripheral rolling surfaces of the rollers 29 and the inclined surface 26 of the groove 25. In the starting position of the piston 5 , which is shown in Figure 3, the pipe 10 is highly elastically compressed, that is to say crushed and has a minimum flow section. It is easily understood that during the displacement of the piston 5 under the effect of the spring 13 in the direction of the front wall 2 of the housing 1, due to the inclination of the surface 26, the degree of crushing decreases and the cross section of flow increases. By an appropriate choice of the inclination of the surface 26 and in general, by giving the latter an appropriate appearance, the flow rate of the liquid discharged from the container 8 through the pipe 10 can be kept constant.
Dans une autre version de réalisation représentée à la figure 4, le dispositif 28 pourrait être réalisé sous forme d'un chariot pourvu d'un certain nombre de galets 29 juxtaposés sur une longueur correspondante à la longueur de la baguette de friction 16 à la figure 1. Dans ce cas, la surface 26 de la rainure 25 s'étend parallèlement à 1'axe du boîtier sur une longueur correspondant à la longueur de la baguette de friction fixe 17 de la figure 1. Au-delà de cette partie, jusqu'au niveau de la paroi frontale 2 du boîtier 1, elle est en retrait de façon à ce que le tuyau 10 ne subisse une déformation de sa section transversale par les galets 29 en fonction du déplacement du piston 5 que sur une longueur qui dépend de façon sensiblement linéaire du déplacement du piston.In another embodiment shown in Figure 4, the device 28 could be in the form of a carriage provided with a number of rollers 29 juxtaposed over a length corresponding to the length of the friction rod 16 in the figure 1. In this case, the surface 26 of the groove 25 extends parallel to the axis of the housing over a length corresponding to the length of the fixed friction rod 17 of FIG. 1. Beyond this part, up to 'at the front wall 2 of the housing 1, it is set back so that the pipe 10 does not undergo a deformation of its cross section by the rollers 29 as a function of the displacement of the piston 5 only over a length which depends on way substantially linear displacement of the piston.
En 42 on a représenté des contre-galets par lesquels le chariot prend appui sur la paroi radialement interne de la rainure, par exemple, de part et d'autre de la fente 27.At 42 there are shown counter-rollers by which the carriage bears on the radially internal wall of the groove, for example, on either side of the slot 27.
La figure 5 montre un deuxième mode de réalisation du système selon l'invention où le dispositif poussoir du piston 5 est formé essentiellement par une cartouche 30 remplie par exemple de l'air sous pression. La cartouche 30 est susceptible d'être solidarisée de l'organe de fermeture amovible du boîtier 1 réalisé sous forme d'un chapeau 31 pouvant être vissé sur le boîtier 1. La cartouche présente à son extrémité en regard du piston 5 un orifice représenté schématiquement en 32 à travers lequel l'air sous pression puisse s'échapper progressivement. Ainsi, une pression peut s'établir dans l'espace 33 entre la cartouche et le piston 5 d'une valeur appropriée pour pousser le piston 5 dans la direction de la compression axiale du récipient 8.FIG. 5 shows a second embodiment of the system according to the invention in which the pusher device of the piston 5 is essentially formed by a cartridge 30 filled for example with pressurized air. The cartridge 30 is capable of being secured to the removable closing member of the housing 1 produced in the form of a cap 31 which can be screwed onto the housing 1. The cartridge has at its end opposite the piston 5 an orifice shown diagrammatically at 32 through which the pressurized air can gradually escape. Thus, a pressure can be established in the space 33 between the cartridge and the piston 5 of a value suitable for pushing the piston 5 in the direction of the axial compression of the container 8.
Pour maintenir constante la pression dans l'espace 33, le boîtier 1 est pourvu d'un dispositif 34 de régulation de la pression. Dans l'exemple représenté, le dispositif 34 dont les dimensions sont exagérées dans un souci de plus grande clarté de la représentation comprend une chambre 35 qui communique avec l'espace 33 à travers un canal 36 qui traverse la paroi du boîtier 1 et est obturable par un clapet 37 repoussé dans sa position d'obturation par un ressort 38 dont la force de rappel est réglable à l'aide d'une vis de réglage 39 dans la paroi externe de la chambre 35. Ainsi la pression dans la chambre 33 qui provoque l'ouverture du clapet 37 peut être ajustée. On comprend aisément que le dispositif 34 permet de maintenir à l'intérieur de la chambre 33 une pression dont la limite supérieure est déterminée par le ressort 38.To keep the pressure in the space 33 constant, the housing 1 is provided with a device 34 for regulating the pressure. In the example shown, the device 34 whose dimensions are exaggerated for the sake of greater clarity of the representation comprises a chamber 35 which communicates with the space 33 through a channel 36 which passes through the wall of the housing 1 and is closable by a valve 37 pushed back into its closed position by a spring 38, the restoring force of which can be adjusted using an adjusting screw 39 in the external wall of the chamber 35. Thus the pressure in the chamber 33 which causes the valve 37 to open can be adjusted. It is easy to understand that the device 34 makes it possible to maintain inside the chamber 33 a pressure whose upper limit is determined by the spring 38.
Un deuxième dispositif de réglage 40 de la pression inférieure dans l'espace 33 est prévu sur la paroi frontale 2 du boîtier. Ce dispositif permet une variation de la section transversale d'écoulement du liquide du tuyau flexible 10. Il pourrait comprendre une vis de réglage 41 ou être de tout autre matière appropriée et connue.A second device 40 for adjusting the lower pressure in the space 33 is provided on the front wall 2 of the housing. This device allows a variation in the cross-section of flow of the liquid from the flexible pipe 10. It could comprise an adjustment screw 41 or be of any other suitable and known material.
La pression ainsi maintenue constante sera choisie de façon à obtenir que le débit de liquide refoulé du récipient 8 à travers le tuyau 10, présente la valeur souhaitée.The pressure thus kept constant will be chosen so as to obtain that the flow rate of liquid discharged from the container 8 through the pipe 10 has the desired value.
Concernant la cartouche 30 formant la source de l'air sous pression, elle peut être réalisée de façon à être facilement rechargeable en l'équipant par exemple d'un dispositif à soupape connu en soi, tel que par exemple utilisé pourdes pneus gonflables.As regards the cartridge 30 forming the source of the pressurized air, it can be produced so as to be easily refillable by equipping it, for example, with a valve device known per se, such as for example used for inflatable tires.
Il est à noter que de nombreuses modifications peuvent être apportées au système selon l'invention qui est représenté. Ainsi le récipient 8 peut être réalisé de toute autre manière connue appropriée. Il importe seulement qu'il soit axialement compressible. De plus, tout autre dispositif poussoir approprié peut être utilisé pour imprimer au piston sa course de compression du récipient. On pourrait aussi envisager de supprimer le piston en donnant au fond du récipient une rigidité suffisante pour qu'il puisse remplacer le piston. Le dispositif pour maintenir constant le débit du liquide refoulé du récipient 8 peut également être réalisé de toute autre manière connue appropriée par exemple pour -faire varier la résistance hydraulique du tuyau 10 en fonction du déplacement du piston 5 pour compenser ainsi la variation de la force du moyen poussoir du piston. Les deux dispositifs de réglage 34, 40 de pression dans l'espace 33 pourraient être remplacés par un détendeur du type connu qui équiperait l'orifice de sortie de la cartouche.It should be noted that many modifications can be made to the system according to the invention which is shown. Thus the container 8 can be produced in any other suitable known manner. It only matters that it is axially compressible. In addition, any other suitable pusher device can be used to print on the piston its compression stroke of the container. One could also consider removing the piston by giving the bottom of the container sufficient rigidity so that it can replace the piston. The device for maintaining constant the flow rate of the liquid discharged from the container 8 can also be produced in any other known known manner suitable for example for varying the hydraulic resistance of the pipe 10 as a function of the displacement of the piston 5 to thereby compensate for the variation in the force of the piston plunger. The two adjustment devices 34, 40 for pressure in space 33 could be replaced by a regulator of the known type which would equip the outlet orifice of the cartridge.
Bien entendu, on pourrait également remplacer le ressort 13 des figures 1 et 2 par un certain nombre de ressorts montés en parallèle. Il est aussi envisageable d'utiliser d'autres types de ressorts que des ressorts hélicoïdaux.Of course, one could also replace the spring 13 of Figures 1 and 2 by a number of springs mounted in parallel. It is also conceivable to use other types of springs than helical springs.
Le boîtier 1 sera avantageusement réalisé en un matériau léger, par exemple par moulage, pour réduire au maximum son poids. Il pourrait être pourvu d'une sangle pour être facilement portable par exemple à la taille par la personne sous perfusion. Ainsi celle-ci peut se déplacer aisément sans être particulièrement gênée par le système de perfusion qu'elle porte sur elle.The housing 1 will advantageously be made of a light material, for example by molding, to reduce its weight as much as possible. It could be provided with a strap to be easily portable for example at the waist by the person on an infusion. Thus it can move easily without being particularly hampered by the infusion system that it carries on it.
Les dimensions du boîtier sont fonction du volume du récipient et du dispositif poussoir. Elles seront relativement faibles. Par exemple, le diamètre du boîtier pourrait être de l'ordre de 5 à 10 cm tandis que la longueur pourrait avoir une valeur de l'ordre de 15 à 20 cm. Par ailleurs, il est également possible d'associer au piston 5 un élément formant index mobile permettant de visualiser la position du piston relativement au boîtier 1. The dimensions of the housing depend on the volume of the container and the pusher device. They will be relatively small. For example, the diameter of the case could be of the order of 5 to 10 cm while the length could have a value of the order of 15 to 20 cm. Furthermore, it is also possible to associate with the piston 5 a movable index element making it possible to view the position of the piston relative to the housing 1.

Claims

Revendications. Claims.
1. Système pour faire une perfusion d'un liquide tel qu'un sérum dans une voie sanguine notamment d'un être humain, du type comprenant un récipient (8) contenant ledit liquide, qui est relié par un tuyau:à la personne, présente une configuration axialement compressible dont au moins la paroi latérale (9) est réalisée en un matériau souple et est placée dans un boîtier (1) portable par la personne sous perfusion, en prenant appui par son extrémité avant de sortie du liquide sur une paroi d'appui (2) du boîtier (1) et par son extrémité arrière fermée sur une surface (5) axialement mobile dans le boîtier (1), sous l'effet d'un dispositif poussoir (13, 30) de ladite surface (5) dans la direction de compression axiale du récipient, pour déplacer le liquide hors dudit récipient dans la voie sanguine précitée, caractérisé en ce que le dispositif poussoir comporte des moyens propulseurs (13, 30) qui sont interposés entre ledit piston (5) et le fond (4) du boîtier (1) et en ce que le système comprend des moyens de réglage (14) du débit du liquide chassé du récipient, lors de la course de compression du piston (5).1. System for making an infusion of a liquid such as a serum into a blood path, in particular of a human being, of the type comprising a container (8) containing said liquid, which is connected by a hose : to the person, has an axially compressible configuration of which at least the side wall (9) is made of a flexible material and is placed in a case (1) portable by the person on an infusion, taking support by its front end of the liquid outlet on a wall support (2) of the housing (1) and by its rear end closed on a surface (5) axially movable in the housing (1), under the effect of a pusher device (13, 30) of said surface ( 5) in the direction of axial compression of the container, to move the liquid out of said container in the aforementioned blood path, characterized in that the pusher device comprises propellant means (13, 30) which are interposed between said piston (5) and the bottom (4) of the case r (1) and in that the system comprises means (14) for adjusting the flow rate of the liquid expelled from the container, during the compression stroke of the piston (5).
2. Système selon la revendication 1, caractérisé en ce que le dispositif poussoir comporte des moyens de ressorts (13) à l'état initial précontraint, qui prennent appui par une extrémité au fond (4) du boîtier (1) et par l'autre extrémité sur le piston (5) précité.2. System according to claim 1, characterized in that the pusher device comprises spring means (13) in the pre-stressed initial state, which bear by one end at the bottom (4) of the housing (1) and by the other end on the aforementioned piston (5).
3. Système selon la revendication 2, caractérisé en ce que les moyens de réglage (14) comportent au moins un dispositif à baguettes de friction en contact de friction mutuel, dont l'une (16) est solidaire du piston mobile (5), tandis que l'autre (17) est solidaire du boîtier, la surface de contact des baguettes diminuant progressivement lors du déplacement de compression axiale du récipient (8), du piston (5).3. System according to claim 2, characterized in that the adjustment means (14) comprise at least one device with friction rods in mutual friction contact, one of which (16) is integral with the movable piston (5), while the other (17) is integral with the housing, the contact surface of the rods gradually decreasing during the compression displacement axial of the container (8), of the piston (5).
4. Système selon la revendication 2, caractérisé en ce que les moyens de réglage (14) comportent un dispositif de diminution progressive de la résistance hydraulique du conduit d'écoulement du liquide de perfusion hors du récipient (8) vers la voie sanguine précitée, lors du déplacement du piston (5) vers sa position de compression du récipient (8).4. System according to claim 2, characterized in that the adjustment means (14) comprise a device for progressive reduction of the hydraulic resistance of the flow conduit for the perfusion liquid out of the container (8) towards the aforementioned blood path, when the piston (5) moves to its container compression position (8).
5. Système selon la revendication 4, caractérisé en ce que le conduit précité est un tuyau (10) en un matériau élastiquement déformable et en ce que le dispositif (14) de variation de la résistance hydraulique précitée est formée par des moyens de variations de la section transversale dudit tuyau (10), avantageusement formé par au moins un galet (29) monté rotatif dans un chariot solidaire du piston (5), le tuyau étant pris entre ledit galet (39) et une surface d'appui solidaire du boîtier (1) située à une distance dudit galet qui varie en fonction du déplacement du piston.5. System according to claim 4, characterized in that the aforementioned conduit is a pipe (10) in an elastically deformable material and in that the device (14) for varying the aforementioned hydraulic resistance is formed by means of variations of the cross section of said pipe (10), advantageously formed by at least one roller (29) rotatably mounted in a carriage secured to the piston (5), the pipe being taken between said roller (39) and a bearing surface secured to the housing (1) located at a distance from said roller which varies as a function of the displacement of the piston.
6. Système selon la revendication 1, caractérisé en ce que le dispositif poussoir comprend une cartouche (30) remplie d'un gaz sous pression formant une source de gaz se répandant dans le boîtier (1) à une pression sensiblement constante et agissant sur un piston (5) monté axialement mobile dans le boîtier et dont la surface opposée à celle exposée au gaz constitute la surface mobile précitée.6. System according to claim 1, characterized in that the pusher device comprises a cartridge (30) filled with a pressurized gas forming a source of gas spreading in the housing (1) at a substantially constant pressure and acting on a piston (5) mounted axially movable in the housing and whose surface opposite to that exposed to the gas constitutes the aforementioned movable surface.
7. Système selon la revendication 5, caractérisé en ce que le dispositif de réglage est formé par des moyens (34, 40) de régulation de la pression agissant à l'intérieur du boîtier (l) sur le piston (5).7. System according to claim 5, characterized in that the adjustment device is formed by means (34, 40) for regulating the pressure acting inside the housing (l) on the piston (5).
8. Système selon la revendication 6 ou 7, caractérisé en ce que la cartouche précitée (30) est rechargeable.8. System according to claim 6 or 7, characterized in that the aforementioned cartridge (30) is refillable.
9. Système selon l'une des revendications 1 à 5, caractérisé en ce que les moyens de ressort comportent un ou plusieurs ressorts hélicoïdaux (13) montés en parallèle.9. System according to one of claims 1 to 5, characterized in that the spring means comprise one or more helical springs (13) mounted in parallel.
10. Système selon l'une des revendications 1 à 5 ou 9, caractérisé en ce que le fond (4) sur lequel prennent appui les moyens de ressort est formé par un corps creux de logement dudit moyen ressort, qui est susceptible d'être vissé dans l'extrémité correspondante du boîtier (1).10. System according to one of claims 1 to 5 or 9, characterized in that the bottom (4) on which the spring means bear is formed by a hollow housing of said spring means, which is capable of being screwed into the corresponding end of the housing (1).
il. Système selon l'une des revendications précédentes, caractérisé en ce que le boîtier est pourvu de moyens permettant à la personne de le porter avantageusement autour de la taille, tel qu'une sangle. he. System according to one of the preceding claims, characterized in that the housing is provided with means allowing the person to wear it advantageously around the waist, such as a strap.
PCT/FR1989/000234 1988-05-17 1989-05-17 System for infusing a liquid into a blood vessel in particular of a human being WO1989011303A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR88/06595 1988-05-17
FR8806595A FR2631551A1 (en) 1988-05-17 1988-05-17 SYSTEM FOR PERFUSION OF A LIQUID INTO A BLOOD PATH, PARTICULARLY OF A HUMAN BEING

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WO (1) WO1989011303A1 (en)

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GB2304584A (en) * 1995-08-23 1997-03-26 Graham Cameron Grant Infusion device comprising a collapsible bag and a movable wall
DE19907744A1 (en) * 1999-02-23 2000-08-24 Backes Claus H Unit for intracorporal injections comprises a space for a bag with the injection medium, and a device allowing the bag to be subjected directly or indirectly to a pressurized fluid
US6406458B1 (en) 1995-08-09 2002-06-18 Premetec Ab Pressure infusion apparatus
WO2016174099A1 (en) * 2015-04-28 2016-11-03 Sanofi-Aventis Deutschland Gmbh Flexible container for an injection device

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US4447232A (en) * 1982-05-21 1984-05-08 Repro-Med Systems, Inc. Spring-operated liquid-dispensing device
WO1986003978A1 (en) * 1985-01-07 1986-07-17 Baxter Travenol Laboratories, Inc. Infusor having a distal flow regulator

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US3902635A (en) * 1973-03-05 1975-09-02 Walter J Jinotti Fluid dispensing apparatus
DE3517927C1 (en) * 1985-05-18 1986-07-24 B. Braun Melsungen Ag, 3508 Melsungen Infusion pump
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US3685697A (en) * 1969-01-17 1972-08-22 Lear Siegler Inc Portable infusion pump
US3625401A (en) * 1969-11-20 1971-12-07 John Vaden Terry Pump for blood plasma and the like
GB2054381A (en) * 1979-06-11 1981-02-18 Unisearch Ltd Infusion device
US4447232A (en) * 1982-05-21 1984-05-08 Repro-Med Systems, Inc. Spring-operated liquid-dispensing device
WO1986003978A1 (en) * 1985-01-07 1986-07-17 Baxter Travenol Laboratories, Inc. Infusor having a distal flow regulator

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406458B1 (en) 1995-08-09 2002-06-18 Premetec Ab Pressure infusion apparatus
GB2304584A (en) * 1995-08-23 1997-03-26 Graham Cameron Grant Infusion device comprising a collapsible bag and a movable wall
DE19907744A1 (en) * 1999-02-23 2000-08-24 Backes Claus H Unit for intracorporal injections comprises a space for a bag with the injection medium, and a device allowing the bag to be subjected directly or indirectly to a pressurized fluid
WO2016174099A1 (en) * 2015-04-28 2016-11-03 Sanofi-Aventis Deutschland Gmbh Flexible container for an injection device
US11224690B2 (en) 2015-04-28 2022-01-18 Sanofi-Aventis Deutschland Gmbh Flexible container for an injection device

Also Published As

Publication number Publication date
EP0372049A1 (en) 1990-06-13
FR2631551A1 (en) 1989-11-24

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