WO1991000082A1 - Antimicrobial polymeric bisbiguanides - Google Patents
Antimicrobial polymeric bisbiguanides Download PDFInfo
- Publication number
- WO1991000082A1 WO1991000082A1 PCT/US1990/003364 US9003364W WO9100082A1 WO 1991000082 A1 WO1991000082 A1 WO 1991000082A1 US 9003364 W US9003364 W US 9003364W WO 9100082 A1 WO9100082 A1 WO 9100082A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bisbiguanides
- antimicrobial polymeric
- alkylene
- antimicrobial
- polymeric
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Antimicrobial polymeric bisbiguanides capped with alkylene pyrrolidonyl groups having formula (I), where X is C2-C4 alkylene; Y is a bivalent bridging group; and n is at least 2; and acid addition salts thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019910702020A KR920702677A (en) | 1989-07-03 | 1990-06-18 | Antimicrobial Polymer Bisbiguanides |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/374,891 US4954636A (en) | 1989-07-03 | 1989-07-03 | Antimicrobial polymeric bisbiguanides |
US374,891 | 1989-07-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1991000082A1 true WO1991000082A1 (en) | 1991-01-10 |
WO1991000082A2 WO1991000082A2 (en) | 1991-01-10 |
Family
ID=
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3428576A (en) * | 1965-11-26 | 1969-02-18 | Ici Ltd | Manufacture of polymeric diguanides |
US3468898A (en) * | 1966-05-26 | 1969-09-23 | Sterling Drug Inc | Bridged bis-biguanides and bis-guanidines |
US4022834A (en) * | 1972-03-16 | 1977-05-10 | A/S Farmaceutisk Industri | Antibacterially active hexamethylene-bis-biguanides |
US4567174A (en) * | 1984-05-07 | 1986-01-28 | Imperial Chemical Industries Plc | Bis(1-substituted biguanide) derivatives |
US4670592A (en) * | 1983-05-09 | 1987-06-02 | Imperial Chemical Industries Plc | Bisbiguanide compounds |
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3428576A (en) * | 1965-11-26 | 1969-02-18 | Ici Ltd | Manufacture of polymeric diguanides |
US3468898A (en) * | 1966-05-26 | 1969-09-23 | Sterling Drug Inc | Bridged bis-biguanides and bis-guanidines |
US4022834A (en) * | 1972-03-16 | 1977-05-10 | A/S Farmaceutisk Industri | Antibacterially active hexamethylene-bis-biguanides |
US4670592A (en) * | 1983-05-09 | 1987-06-02 | Imperial Chemical Industries Plc | Bisbiguanide compounds |
US4567174A (en) * | 1984-05-07 | 1986-01-28 | Imperial Chemical Industries Plc | Bis(1-substituted biguanide) derivatives |
Non-Patent Citations (1)
Title |
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See also references of EP0480999A4 * |
Also Published As
Publication number | Publication date |
---|---|
US4954636A (en) | 1990-09-04 |
JPH05504938A (en) | 1993-07-29 |
CA2019979A1 (en) | 1991-01-03 |
AU5957590A (en) | 1991-01-17 |
EP0480999A4 (en) | 1992-06-03 |
EP0480999A1 (en) | 1992-04-22 |
KR920702677A (en) | 1992-10-06 |
AU631444B2 (en) | 1992-11-26 |
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