WO1991007928A1 - Angioplasty stent for use with a catheter - Google Patents

Angioplasty stent for use with a catheter Download PDF

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Publication number
WO1991007928A1
WO1991007928A1 PCT/GB1990/001805 GB9001805W WO9107928A1 WO 1991007928 A1 WO1991007928 A1 WO 1991007928A1 GB 9001805 W GB9001805 W GB 9001805W WO 9107928 A1 WO9107928 A1 WO 9107928A1
Authority
WO
WIPO (PCT)
Prior art keywords
stent
catheter
artery
tube
balloon
Prior art date
Application number
PCT/GB1990/001805
Other languages
French (fr)
Inventor
Martin Terry Rothman
Original Assignee
Martin Terry Rothman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martin Terry Rothman filed Critical Martin Terry Rothman
Publication of WO1991007928A1 publication Critical patent/WO1991007928A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts

Definitions

  • Angioplasty stent for use with a catheter
  • the present invention relates to catheters for insertion into the human body.
  • catheters for different medical purposes and the present invention is particularly concerned with the use of so-called balloon-type catheters which are used to flatten the interior of a diseased artery in order to increase the internal cross-section of the artery at the point where it would otherwise be constricted by a diseased area or plaque.
  • a known treatment involves inserting a balloon catheter into the artery, expanding the balloon at the point of the diseased area to thus compress that diseased area into the wall of the artery. The balloon is then deflated and the catheter withdrawn from within the patient.
  • stent which consists essentially of a fine wire element, made of stainless steel or the like, which is used to, as it were, shore-up the above-mentioned projecting diseased portions.
  • the "stent” has to be in a collapsed state in order to enable it to be inserted into the artery.
  • the collapsed “stent” is then expanded, once it is in the desired position, in order to shore-up the aforesaid diseased portion.
  • One way of expanding the “stent” is to mount it on a balloon which can be inflated by remote control from the end of the catheter which is outside the patient's body. Such a “stent” is sometimes referred to as being “balloon expandable”.
  • An alternative method employs a so-called “self-expanding stent".
  • the "stent” is collapsed onto a centre tube under tension and held in the collapsed state by a sleeve.
  • the sleeve containing the collapsed "stent” is inserted into the patient's artery to bring the "stent” into the vicinity of the diseased area.
  • the sleeve is then withdrawn to expose the collapsed "stent” which can thus expand as a result of its having been collapsed under tension and contained by the sleeve.
  • the expanded “stent” pushes the aforementioned diseased portions back into * the wall of the artery and holds them there.
  • the “stent” remains permanently in the patient's artery.
  • the present invention is concerned with providing an alternative to the above known arrangements, which alternative will be simpler to use, have a wider application of use and in addition have the advantage of not leaving the "stent" permanently embedded in the artery wall.
  • a catheter for flattening the interior wall of an artery or other organ includes the following combination of features:
  • the "stent” comprises an element which in its contracted state is substantially linear to fit in the catheter tube but which when free of the catheter tube adopts an expanded hollow configuration whereby it can press against the interior surface of an artery but still allow blood flow through the artery.
  • Figure 1 is a partial cross-sectional view showing the use of a prior art catheter for flattening a diseased area formed on the inside of a patient's artery;
  • Figure 2 is a view similar to Figure 1 showing the insertion of one embodiment of a catheter according to the present invention into the patient's artery shown in Figure 1;
  • Figure 3 is a view similar to Figure 2 showing a later stage of the insertion of the embodiment shown in Figure 2;
  • Figure 4 is a view similar to Figures 2 and 3 showing the final stage of the insertion of the "stent" of Figure 2 with it in its operative position within a patient's artery;
  • Figure 5 is a view similar to Figure 2 showing the insertion of a second embodiment of a catheter according to the present invention into the patient's artery shown in Figure 1.
  • Figure 1 shows the use of a known type of so-called balloon catheter used to flatten a diseased area within a patient's artery.
  • the artery 1 has a diseased area indicated by A which has the effect of restricting blood flow through the artery.
  • the balloon is inflated by feeding liquid into it through a lumen formed in the catheter or through an annular space formed around the outside of the catheter.
  • the method of inserting the balloon catheter into the artery involves the use of a lead wire 3a.
  • the lead wire 3a is first inserted into the artery, the catheter carrying the balloon then being slid along the wire to the position shown.
  • the lead wire 3a could be incorporated into the catheter.
  • such action will have the desired effect of more or less permanently compressing the diseased area A into the wall of the artery 1 and thus increasing the cross-section of the artery at that point to enable blood flow to be improved.
  • fragments of the diseased portion A shown as a in Figure 2 fall back, as it were, into the artery passage 4 when the balloon 3 is deflated and withdrawn.
  • a catheter according to one embcdiiront of the present invention is shown in Figure 2 and comprises a tube 5 containing a "stent" element 6 carried on the distal end of a very thin wire 7 which extends to the other proximal end of the catheter tube 5.
  • the preferred material for the "stent" element 6 and the wire 7 is stainless steel, tantalum, or a nylon type polymer.
  • a substantially straight lead portion 6a of the "stent" is at the extreme distal end to assist the insertion of the catheter into the patient's artery.
  • This lead portion 6a is typically 1 to 3 cm long.
  • the catheter tube 5 containing the "stent" element 6 is inserted into the patient's artery 1 as illustrated in Figure 2.
  • the diameter of the coiled configuration is substantially larger than the internal diameter of the catheter tube 5.
  • stents having a range of diameters would be provided for different applications. Typically the range could be of 2 to 4.5 mm diameter in0.5 ir steps.
  • the catheter tube 5 can then be withdrawn from the patient's artery 1 to leave the "stent" element 6 in the position shown in Figure 4, in which the expanded coils of the "stent” element 6 hold the portions a of the diseased area A back against the wall of the artery 1.
  • a range of different sizes of "stent” would be provided, both in terms of coil diameter and axial length of the coiled portion. Typically the latter could be in the range 1 to 3 cm.
  • the "stent" 6 presents the minimum resistance to the flow of blood through the artery, whilst at the same time ensuring that the diseased area A and in particular the portions a , do not impede that flow.
  • FIG 5 shows a second embodiment of the present invention in which the coiled temporary "stent" 6 is used in conjunction with a balloon catheter 3 of the type already shown in Figure 1.
  • the "stent” is incorporated into such a catheter instead of being used completely separately from the balloon catheter.
  • the balloon catheter would be operated, as shown in Figure 1, to flatten the diseased portion A of the wall of the artery 1.
  • the balloon would then be deflated and withdrawn together with the catheter tube to thus expose or release the coiled "stent" 6 to enable it to adopt the expanded configuration shown in Figures 3 and 4.
  • the "stent" of the present invention unlike those of the prior art, is not intended to be permanently left in the patient's artery.

Abstract

A ''stent'' (6) for use in conjunction with a balloon type catheter (2), in order to shore-up tissue (A) which has been damaged by use of the balloon type catheter (2), is characterised in that it comprises a coil-like spring member which is contained in a substantially linear stressed condition within the catheter (2) for transport to the diseased area (A) and which when released from the catheter (2) adopts a coiled configuration (6b) to hold the damaged tissue (A) in place whilst at the same time allowing blood flow.

Description

Angioplasty stent for use with a catheter
The present invention relates to catheters for insertion into the human body.
There are many designs of catheters for different medical purposes and the present invention is particularly concerned with the use of so-called balloon-type catheters which are used to flatten the interior of a diseased artery in order to increase the internal cross-section of the artery at the point where it would otherwise be constricted by a diseased area or plaque.
A known treatment involves inserting a balloon catheter into the artery, expanding the balloon at the point of the diseased area to thus compress that diseased area into the wall of the artery. The balloon is then deflated and the catheter withdrawn from within the patient.
Whilst in many cases the compressed diseased area will remain compressed and thus leave the artery relatively open for the flow of blood, there are occasions when upon extraction of the deflated balloon portions of the diseased area fall back into the passageway of the artery to thereby continue to obstruct it whilst still being connected to the internal wall of the artery.
There are a number of known approaches to dealing with this particular problem.
One approach is to use a so-called "stent" which consists essentially of a fine wire element, made of stainless steel or the like, which is used to, as it were, shore-up the above-mentioned projecting diseased portions.
There are a number of known ways in which the so-called "stent" can be inserted into the artery and brought into an operative position in relation to the diseased portion.
Clearly, the "stent" has to be in a collapsed state in order to enable it to be inserted into the artery. There are different ways in which the collapsed "stent" is then expanded, once it is in the desired position, in order to shore-up the aforesaid diseased portion. One way of expanding the "stent" is to mount it on a balloon which can be inflated by remote control from the end of the catheter which is outside the patient's body. Such a "stent" is sometimes referred to as being "balloon expandable".
An alternative method employs a so-called "self-expanding stent". In this arrangement, the "stent" is collapsed onto a centre tube under tension and held in the collapsed state by a sleeve. The sleeve containing the collapsed "stent" is inserted into the patient's artery to bring the "stent" into the vicinity of the diseased area. The sleeve is then withdrawn to expose the collapsed "stent" which can thus expand as a result of its having been collapsed under tension and contained by the sleeve.
With these known arrangements, the expanded "stent" pushes the aforementioned diseased portions back into * the wall of the artery and holds them there. The "stent" remains permanently in the patient's artery.
The present invention is concerned with providing an alternative to the above known arrangements, which alternative will be simpler to use, have a wider application of use and in addition have the advantage of not leaving the "stent" permanently embedded in the artery wall.
According to the present invention, a catheter for flattening the interior wall of an artery or other organ includes the following combination of features:
a) a balloon catheter or simple catheter tube;
b) a "stent" contained within a) in a stressed collapsed condition, the tube a) and "stent" being movable axially with respect to one another to progressively bring the "stent" outside the tube, the "stent" then being radially expandable;
characterised in that the "stent" comprises an element which in its contracted state is substantially linear to fit in the catheter tube but which when free of the catheter tube adopts an expanded hollow configuration whereby it can press against the interior surface of an artery but still allow blood flow through the artery.
How the invention may be carried out will now be described in more detail, but by way of example only, with reference to the accompanying drawings in which:
Figure 1 is a partial cross-sectional view showing the use of a prior art catheter for flattening a diseased area formed on the inside of a patient's artery;
Figure 2 is a view similar to Figure 1 showing the insertion of one embodiment of a catheter according to the present invention into the patient's artery shown in Figure 1;
Figure 3 is a view similar to Figure 2 showing a later stage of the insertion of the embodiment shown in Figure 2;
Figure 4 is a view similar to Figures 2 and 3 showing the final stage of the insertion of the "stent" of Figure 2 with it in its operative position within a patient's artery; and
Figure 5 is a view similar to Figure 2 showing the insertion of a second embodiment of a catheter according to the present invention into the patient's artery shown in Figure 1. Figure 1 shows the use of a known type of so-called balloon catheter used to flatten a diseased area within a patient's artery.
The artery 1 has a diseased area indicated by A which has the effect of restricting blood flow through the artery.
In order to improve the blood flow, it is known to insert a catheter 2 provided with a balloon device 3, into the artery 1 and to inflate the balloon device
(as illustrated in Figure 1) in order to press the diseased area A back into the wall of the artery 1.
The balloon is inflated by feeding liquid into it through a lumen formed in the catheter or through an annular space formed around the outside of the catheter.
The method of inserting the balloon catheter into the artery involves the use of a lead wire 3a. The lead wire 3a is first inserted into the artery, the catheter carrying the balloon then being slid along the wire to the position shown. Alternatively, the lead wire 3a could be incorporated into the catheter. In most cases such action will have the desired effect of more or less permanently compressing the diseased area A into the wall of the artery 1 and thus increasing the cross-section of the artery at that point to enable blood flow to be improved. However, in a minority of cases, although the majority of the diseased portion A may be so compressed, fragments of the diseased portion A, shown as a in Figure 2, fall back, as it were, into the artery passage 4 when the balloon 3 is deflated and withdrawn.
It is with this problem that the present invention is concerned.
A catheter according to one embcdiiront of the present invention is shown in Figure 2 and comprises a tube 5 containing a "stent" element 6 carried on the distal end of a very thin wire 7 which extends to the other proximal end of the catheter tube 5. The preferred material for the "stent" element 6 and the wire 7 is stainless steel, tantalum, or a nylon type polymer.
In the position shown in Figure 2, the "stent" element
6 is in a stressed condition where it lies substantially linearly within the catheter tube 5. A substantially straight lead portion 6a of the "stent" is at the extreme distal end to assist the insertion of the catheter into the patient's artery. This lead portion 6a is typically 1 to 3 cm long.
The catheter tube 5 containing the "stent" element 6 is inserted into the patient's artery 1 as illustrated in Figure 2.
Further axial movement of the catheter 5 towards the right, in the drawings, brings the distal end of the catheter tube 5 into the vicinity of the diseased area A, as shown in Figure 3. In that position the proximal end of the wire 7 is moved to the right (as viewed in the drawings) in order to in turn move the "stent" element 6 out of the distal end of a catheter tube.5.
As soon as any further portion of the "stent" element 6 becomes free of the catheter tube 5, as the latter is slid to the left as viewed in the drawings, its built in stress will cause it to adopt a coiled configuration as shown at 6b in Figure 3, due to the stress previously built into the wire comprising the "stent" .
The diameter of the coiled configuration is substantially larger than the internal diameter of the catheter tube 5.
In practice "stents" having a range of diameters would be provided for different applications. Typically the range could be of 2 to 4.5 mm diameter in0.5 ir steps.
The catheter tube 5 can then be withdrawn from the patient's artery 1 to leave the "stent" element 6 in the position shown in Figure 4, in which the expanded coils of the "stent" element 6 hold the portions a of the diseased area A back against the wall of the artery 1.
As indicated earlier, a range of different sizes of "stent" would be provided, both in terms of coil diameter and axial length of the coiled portion. Typically the latter could be in the range 1 to 3 cm.
Because of the fine diameter of the wire making up the "stent" element 6 and because of the expanded diameter of its coils, the "stent" 6 presents the minimum resistance to the flow of blood through the artery, whilst at the same time ensuring that the diseased area A and in particular the portions a , do not impede that flow.
Figure 5 shows a second embodiment of the present invention in which the coiled temporary "stent" 6 is used in conjunction with a balloon catheter 3 of the type already shown in Figure 1. In other words, the "stent" is incorporated into such a catheter instead of being used completely separately from the balloon catheter.
With this arrangement the balloon catheter would be operated, as shown in Figure 1, to flatten the diseased portion A of the wall of the artery 1. The balloon would then be deflated and withdrawn together with the catheter tube to thus expose or release the coiled "stent" 6 to enable it to adopt the expanded configuration shown in Figures 3 and 4.
The "stent" of the present invention, unlike those of the prior art, is not intended to be permanently left in the patient's artery.
With the designs of "stent" described above and illustrated in the drawings, it is possible to effect a quick temporary, as it were repair, to the internal wall of the artery 1 whilst either the tissue of the artery heals or whilst a further treatment of the condition is prepared.
Although a specific configuration and construction of "stent" has been illustrated and described, variations could be made within the scope of the present invention.
The essence of the present invention is that, unlike known "stents", the operative element of the "stent" relies on its in-built "memory" to return from its collapsed constrained configuration to its relatively unstressed expanded configuration i.e. a separate mechanism for expanding the "stent" is not required. Within this concept, clearly a number of constructions of "stent" could be employed, of which that illustrated is only one.

Claims

CLAIMS :
1. A catheter for flattening the interior wall of aft artery or other organ includes the following combination of features:
a) a balloon catheter or simple catheter tube;
b) a "stent" contained within a) in a stressed collapsed condition, the tube a) and "stent" being movable axially with respect to one another to progressively bring the "stent" outside the tube, the "stent" then being radially expandable;
characterised in that the "stent" comprises an element which in its contracted state is substantially linear to fit in the catheter tube but which when free of the catheter tube adopts an expanded hollow configuration whereby it can press against the interior surface of an artery but still allow blood flow through the artery.
2. A catheter as claimed in claim 1, in which the operative element of the "stent" comprises a coil spring.
3. A catheter as claimed in claim 2, in which the coil spring is formed on one end of a fine wire adapted to pass the length of the catheter tube.
4. The "stent" as defined in any one of claims 1 to 3 separate from the catheter.
5. A catheter substantially as hereinbefore described with reference to and as shown in Figures 2 to 4 of the accompanying drawings.
6. A "stent" substantially as hereinbefore described with reference to and as shown in Figures 2 to 4 of the accompanying drawings.
PCT/GB1990/001805 1989-11-24 1990-11-22 Angioplasty stent for use with a catheter WO1991007928A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8926551A GB2238245B (en) 1989-11-24 1989-11-24 Catheters
GB8926551.6 1989-11-24

Publications (1)

Publication Number Publication Date
WO1991007928A1 true WO1991007928A1 (en) 1991-06-13

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Application Number Title Priority Date Filing Date
PCT/GB1990/001805 WO1991007928A1 (en) 1989-11-24 1990-11-22 Angioplasty stent for use with a catheter

Country Status (2)

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GB (1) GB2238245B (en)
WO (1) WO1991007928A1 (en)

Cited By (12)

* Cited by examiner, † Cited by third party
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EP0556850A1 (en) * 1992-02-21 1993-08-25 Mintec Inc Intraluminal stent
US5405380A (en) * 1992-10-12 1995-04-11 Schneider (Europe) A.G. Catheter with a vascular support
US5603327A (en) * 1993-02-01 1997-02-18 Endosonics Corporation Ultrasound catheter probe
US5609627A (en) * 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
WO1997027808A1 (en) * 1996-02-02 1997-08-07 Regents Of The University Of California Clot capture coil
US5665115A (en) * 1992-02-21 1997-09-09 Boston Scientific Technology, Inc. Intraluminal stent
US5725571A (en) * 1992-02-03 1998-03-10 Schneider (Europe) A.G. Catheter with a stent
US6010530A (en) * 1995-06-07 2000-01-04 Boston Scientific Technology, Inc. Self-expanding endoluminal prosthesis
AU2006203116B2 (en) * 1996-02-02 2009-05-28 The Regents Of The University Of California Clot capture coil
US7618449B2 (en) 2002-06-12 2009-11-17 Mitral Interventions Method and apparatus for tissue connection
US7758624B2 (en) 2000-11-13 2010-07-20 C. R. Bard, Inc. Implant delivery device
US9656047B1 (en) 2014-12-05 2017-05-23 Anchor Endovascular, Inc. Anchor device for use with catheters

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US5725571A (en) * 1992-02-03 1998-03-10 Schneider (Europe) A.G. Catheter with a stent
US5766237A (en) * 1992-02-21 1998-06-16 Boston Scientific Technologies, Inc. Method of reinforcing a body vessel using a intraluminal stent
US5405377A (en) * 1992-02-21 1995-04-11 Endotech Ltd. Intraluminal stent
US7534256B2 (en) 1992-02-21 2009-05-19 Boston Scientific Scimed, Inc. Intraluminal stent and graft
EP0556850A1 (en) * 1992-02-21 1993-08-25 Mintec Inc Intraluminal stent
US6174328B1 (en) 1992-02-21 2001-01-16 Boston Scientific Technology, Inc. Intraluminal stent and graft
US5665115A (en) * 1992-02-21 1997-09-09 Boston Scientific Technology, Inc. Intraluminal stent
US5683448A (en) * 1992-02-21 1997-11-04 Boston Scientific Technology, Inc. Intraluminal stent and graft
US5405380A (en) * 1992-10-12 1995-04-11 Schneider (Europe) A.G. Catheter with a vascular support
US5626602A (en) * 1992-10-12 1997-05-06 Schneider (Europe) A.G. Catheter with a vascular support
US6283920B1 (en) 1993-02-01 2001-09-04 Endosonics Corporation Ultrasound transducer assembly
US5603327A (en) * 1993-02-01 1997-02-18 Endosonics Corporation Ultrasound catheter probe
US5938615A (en) * 1993-02-01 1999-08-17 Endosonics Corporation Ultrasound catheter probe
US6123673A (en) * 1993-02-01 2000-09-26 Endosonics Corporation Method of making an ultrasound transducer assembly
US5779644A (en) * 1993-02-01 1998-07-14 Endosonics Coporation Ultrasound catheter probe
US6962567B2 (en) 1993-02-01 2005-11-08 Volcano Therapeutics, Inc. Ultrasound transducer assembly
US5609627A (en) * 1994-02-09 1997-03-11 Boston Scientific Technology, Inc. Method for delivering a bifurcated endoluminal prosthesis
US6010530A (en) * 1995-06-07 2000-01-04 Boston Scientific Technology, Inc. Self-expanding endoluminal prosthesis
EP1642540A1 (en) * 1996-02-02 2006-04-05 The Regents Of The University Of California Clot capture coil
US8608754B2 (en) 1996-02-02 2013-12-17 The Regents Of The University Of California Clot capture coil
US6485497B2 (en) 1996-02-02 2002-11-26 The Regents Of The University Of California Method of using a clot capture coil
US6530935B2 (en) 1996-02-02 2003-03-11 Regents Of The University Of California, The Clot capture coil and method of using the same
US6692509B2 (en) 1996-02-02 2004-02-17 Regents Of The University Of California Method of using a clot capture coil
US6692508B2 (en) 1996-02-02 2004-02-17 The Regents Of The University Of California Method of using a clot capture coil
AU733395B2 (en) * 1996-02-02 2001-05-10 Regents Of The University Of California, The Clot capture coil
WO1997027808A1 (en) * 1996-02-02 1997-08-07 Regents Of The University Of California Clot capture coil
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
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GB2238245A (en) 1991-05-29
GB2238245B (en) 1994-04-20
GB8926551D0 (en) 1990-01-17

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