WO1992013502A1 - Artificial heart valve - Google Patents
Artificial heart valve Download PDFInfo
- Publication number
- WO1992013502A1 WO1992013502A1 PCT/ES1992/000014 ES9200014W WO9213502A1 WO 1992013502 A1 WO1992013502 A1 WO 1992013502A1 ES 9200014 W ES9200014 W ES 9200014W WO 9213502 A1 WO9213502 A1 WO 9213502A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- valve
- ring
- masts
- pericardium
- veils
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
Definitions
- the invention relates to a new artificial cardiac valve for replacing the human valves that are sick or dysfunctional and which is part of the group of biological valve substitutes or "bioprostheses" also called valvular Xenografts, that is, valves made of biological tissues. and in this case with caliper peri ⁇ cardio treated with glutaraldehyde and fixed on a flexible reinforcement composed of a polymer called Celcon.
- Ionescu-Shiley pericardium biopró ⁇ esis which was the name under which they were commercialized, were of very low thrombogenicide, probably due to their excellent hydrodynamics, and it was not necessary to administer anticoagulants for life as was the case with other biological valves. implanted in nitral position or with mechanical valve substitutes.
- Esxudios made by the inventor (Biologic * Bioprosthetic Valves, Yorke Medical Books, ⁇ 986) have clinically proven this beneficial aspect.
- an artificial heart valve comprising a flexible reinforcement composed of a valve ring and masts that rise from the ring and define breasts between them, with shell or scallop being the part of the ring corresponding to each breast; opening and closing veils of the valve that are fixed to said armature and which are sized in such a way that said masts are projected beyond the cusp; a coating or forage of pericardium applied to said reinforcement; and some means of fixing the valve to the patient's heart tissue.
- the reinforcement is made of a copolymer of high fatigue resistance acetate, specifically the polymer called Celcon, and has between five and six holes in each breast and in the masts to fix each pre-selected veil of tissue in them.
- the means for fixing the valve consist of a silicone rubber ring, specifically Silastic, covered with tubular polyester fabric, specifically Dacron, to pass the sutures of the patient's ring and implant So the valve.
- the pericardium coating is based on calf pericardial tissue treated with purified glutaraldehyde in a solution buffered with phosphate salt at pH 7.4, without pressure, and has a thickness of ⁇ 6 to 22 mm.
- the valve of the invention has been subjected to various operating tests.
- Figure 1 illustrates the valve armature of the invention
- Figure 2 shows the lining of the armature with treated calf pericardium
- Figure 3 is a sagittal section of the valve of the invention
- Figure 4 shows the valve already assembled with the pericardial veils
- Figure 5 illustrates the internal projection of the valve with the semicircular shape of the three breasts covered with pericardium.
- the valve of the invention includes a reinforcement of a high-strength acetate copolymer, known as Celcon, which is integrated by a valve ring. 1 and some 2 masts that rise from the ring and define breasts between them, being practiced in each breast and in the masts between five and six holes 3 to fix in them each pre-selected veil 4 of pericardial tissue and according to the valve sizes .
- Figure 1 shows the scallop or shell shape of the ring for each breast of the valve.
- FIG. 2 shows a veil 4 separated from the valve, while the veils applied to the valve are shown in dashed lines.
- A the fixation of the pericardium to the masts 2 of the armor, as well as the inner lining or forage, and with B each veil 4 of pre-selected pericardium is shown to be fixed to the masts 2.
- B each veil 4 of pre-selected pericardium is shown to be fixed to the masts 2.
- Fig. 3 the veal peritonum of veil 4 has been designated with A, with B the fixation of the peri ⁇ cardio to the armor, with C the fabric-coated valve ring, with D the sili rubber suture ring - Cona (Silastic) lined with tubular polyester fabric (Dacron) to pass the sutures of the patient's ring and thus implant the valve, and with E the pericardium already fixed to the reinforcement.
- Figure 4 shows in A and B the veils 4 already fixed at the base and along the scallop and the masts 2 of the armor. All the pericardial tissue of the veils is treated with purified glutaraldehyde in phosphate salt buffered solution at pH 7.4 and without Zion.
- Figure 5 illustrates the semi-circular shape of the three sinuses of the valve with an inner pericardium lining that has been designated with 5 and which, as stated, has been applied by sewing to the hard shell.
- each pericardial veil ranges between 0.3 70.45 ⁇ im for valves with outside diameters of 19 to 23 mm, between 0 , 42 and 0.52 mm for valves with outside diameters from 25 to 29 mm and between 0.50 and 0.62 mm for valves with outside diameters from 3 to 33 mm. Therefore, the sizes of the valves to be implanted range from 19 mm in external diameter, including the Dacron coating, and 33 mm.
- the projection from the base of the valve to the top of the masts of the armor with the veils already mounted is, in millimeters, 7 for size 19 »8 for sizes 21 and 23, 9 for size 25, 10 for sizes 27 and 29 and 11 for sizes 3 and 33- Coated inside diameters, in millimeters, are 15 for size 19, 17 for size 21, 19 for size 23, 21 for size 25, 23 for size 27, 25 for size 29, 27 for size 3 and 9 for size 33.
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR929204120A BR9204120A (en) | 1991-02-07 | 1992-02-06 | ARTIFICIAL HEART VALVE |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9100324A ES2028611A6 (en) | 1991-02-07 | 1991-02-07 | Artificial heart valve. |
ESP9100324 | 1991-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1992013502A1 true WO1992013502A1 (en) | 1992-08-20 |
Family
ID=8271120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES1992/000014 WO1992013502A1 (en) | 1991-02-07 | 1992-02-06 | Artificial heart valve |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0532719A1 (en) |
AU (1) | AU1261292A (en) |
BR (1) | BR9204120A (en) |
CA (1) | CA2080138A1 (en) |
ES (1) | ES2028611A6 (en) |
WO (1) | WO1992013502A1 (en) |
Cited By (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5449385A (en) * | 1991-05-08 | 1995-09-12 | Nika Health Products Limited | Support for a heart valve prosthesis |
US5716399A (en) * | 1995-10-06 | 1998-02-10 | Cardiomend Llc | Methods of heart valve repair |
US6102944A (en) * | 1997-03-27 | 2000-08-15 | Edwards Lifesciences Corporation | Methods of tissue heart valve assembly |
US6425902B1 (en) | 2001-05-04 | 2002-07-30 | Cardiomend Llc | Surgical instrument for heart valve reconstruction |
US6598307B2 (en) | 1999-11-17 | 2003-07-29 | Jack W. Love | Device and method for assessing the geometry of a heart valve |
US6869444B2 (en) * | 2000-05-22 | 2005-03-22 | Shlomo Gabbay | Low invasive implantable cardiac prosthesis and method for helping improve operation of a heart valve |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
US8460373B2 (en) | 2002-12-20 | 2013-06-11 | Medtronic, Inc. | Method for implanting a heart valve within an annulus of a patient |
US8641757B2 (en) | 2010-09-10 | 2014-02-04 | Edwards Lifesciences Corporation | Systems for rapidly deploying surgical heart valves |
US8696742B2 (en) | 2009-06-26 | 2014-04-15 | Edwards Lifesciences Corporation | Unitary quick-connect prosthetic heart valve deployment methods |
US8747463B2 (en) | 2003-08-22 | 2014-06-10 | Medtronic, Inc. | Methods of using a prosthesis fixturing device |
US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
US8986374B2 (en) | 2010-05-10 | 2015-03-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9005279B2 (en) | 2010-11-12 | 2015-04-14 | Shlomo Gabbay | Beating heart buttress and implantation method to prevent prolapse of a heart valve |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
US9125741B2 (en) | 2010-09-10 | 2015-09-08 | Edwards Lifesciences Corporation | Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves |
US9155617B2 (en) | 2004-01-23 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic mitral valve |
US9248016B2 (en) | 2009-03-31 | 2016-02-02 | Edwards Lifesciences Corporation | Prosthetic heart valve system |
US9314334B2 (en) | 2008-11-25 | 2016-04-19 | Edwards Lifesciences Corporation | Conformal expansion of prosthetic devices to anatomical shapes |
US9370418B2 (en) | 2010-09-10 | 2016-06-21 | Edwards Lifesciences Corporation | Rapidly deployable surgical heart valves |
US9439762B2 (en) | 2000-06-01 | 2016-09-13 | Edwards Lifesciences Corporation | Methods of implant of a heart valve with a convertible sewing ring |
US9468527B2 (en) | 2013-06-12 | 2016-10-18 | Edwards Lifesciences Corporation | Cardiac implant with integrated suture fasteners |
US9504566B2 (en) | 2014-06-20 | 2016-11-29 | Edwards Lifesciences Corporation | Surgical heart valves identifiable post-implant |
US9549816B2 (en) | 2014-04-03 | 2017-01-24 | Edwards Lifesciences Corporation | Method for manufacturing high durability heart valve |
US9554901B2 (en) | 2010-05-12 | 2017-01-31 | Edwards Lifesciences Corporation | Low gradient prosthetic heart valve |
US9554903B2 (en) | 2005-05-24 | 2017-01-31 | Edwards Lifesciences Corporation | Rapid deployment prosthetic heart valve |
US9603553B2 (en) | 2009-10-27 | 2017-03-28 | Edwards Lifesciences Corporation | Methods of measuring heart valve annuluses for valve replacement |
US9629717B2 (en) | 2001-10-11 | 2017-04-25 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9919137B2 (en) | 2013-08-28 | 2018-03-20 | Edwards Lifesciences Corporation | Integrated balloon catheter inflation system |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US10058425B2 (en) | 2013-03-15 | 2018-08-28 | Edwards Lifesciences Corporation | Methods of assembling a valved aortic conduit |
US10080653B2 (en) | 2015-09-10 | 2018-09-25 | Edwards Lifesciences Corporation | Limited expansion heart valve |
USD846122S1 (en) | 2016-12-16 | 2019-04-16 | Edwards Lifesciences Corporation | Heart valve sizer |
US10307249B2 (en) | 2014-04-30 | 2019-06-04 | Edwards Lifesciences Corporation | Holder and deployment system for surgical heart valves |
US10441415B2 (en) | 2013-09-20 | 2019-10-15 | Edwards Lifesciences Corporation | Heart valves with increased effective orifice area |
US10456246B2 (en) | 2015-07-02 | 2019-10-29 | Edwards Lifesciences Corporation | Integrated hybrid heart valves |
US10456245B2 (en) | 2016-05-16 | 2019-10-29 | Edwards Lifesciences Corporation | System and method for applying material to a stent |
US10463485B2 (en) | 2017-04-06 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve holders with automatic deploying mechanisms |
USD867594S1 (en) | 2015-06-19 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10543080B2 (en) | 2011-05-20 | 2020-01-28 | Edwards Lifesciences Corporation | Methods of making encapsulated heart valves |
US10667904B2 (en) | 2016-03-08 | 2020-06-02 | Edwards Lifesciences Corporation | Valve implant with integrated sensor and transmitter |
US10695170B2 (en) | 2015-07-02 | 2020-06-30 | Edwards Lifesciences Corporation | Hybrid heart valves adapted for post-implant expansion |
US10722316B2 (en) | 2013-11-06 | 2020-07-28 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US10799353B2 (en) | 2017-04-28 | 2020-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve with collapsible holder |
USD908874S1 (en) | 2018-07-11 | 2021-01-26 | Edwards Lifesciences Corporation | Collapsible heart valve sizer |
US11007058B2 (en) | 2013-03-15 | 2021-05-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
US11135057B2 (en) | 2017-06-21 | 2021-10-05 | Edwards Lifesciences Corporation | Dual-wireform limited expansion heart valves |
US11337805B2 (en) | 2018-01-23 | 2022-05-24 | Edwards Lifesciences Corporation | Prosthetic valve holders, systems, and methods |
US11554012B2 (en) | 2019-12-16 | 2023-01-17 | Edwards Lifesciences Corporation | Valve holder assembly with suture looping protection |
US11690709B2 (en) | 2015-09-02 | 2023-07-04 | Edwards Lifesciences Corporation | Methods for securing a transcatheter valve to a bioprosthetic cardiac structure |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0073624A1 (en) * | 1981-08-24 | 1983-03-09 | McNeilab, Inc. | Method for preparing tissue heart valve |
EP0084395B1 (en) * | 1982-01-20 | 1986-08-13 | Martin Morris Black | Artificial heart valves |
EP0125393B1 (en) * | 1980-11-03 | 1987-12-09 | Shiley Incorporated | Prosthetic heart valve |
EP0179562B1 (en) * | 1984-09-28 | 1989-07-12 | The University of Glasgow, University Court | A heart valve prosthesis |
EP0155245B1 (en) * | 1984-03-16 | 1990-05-02 | SORIN BIOMEDICA S.p.A. | Cardiac valve prosthesis with valve flaps of biological tissues |
-
1991
- 1991-02-07 ES ES9100324A patent/ES2028611A6/en not_active Expired - Lifetime
-
1992
- 1992-02-06 AU AU12612/92A patent/AU1261292A/en not_active Abandoned
- 1992-02-06 CA CA 2080138 patent/CA2080138A1/en not_active Abandoned
- 1992-02-06 WO PCT/ES1992/000014 patent/WO1992013502A1/en not_active Application Discontinuation
- 1992-02-06 EP EP19920904900 patent/EP0532719A1/en not_active Withdrawn
- 1992-02-06 BR BR929204120A patent/BR9204120A/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0125393B1 (en) * | 1980-11-03 | 1987-12-09 | Shiley Incorporated | Prosthetic heart valve |
EP0073624A1 (en) * | 1981-08-24 | 1983-03-09 | McNeilab, Inc. | Method for preparing tissue heart valve |
EP0084395B1 (en) * | 1982-01-20 | 1986-08-13 | Martin Morris Black | Artificial heart valves |
EP0155245B1 (en) * | 1984-03-16 | 1990-05-02 | SORIN BIOMEDICA S.p.A. | Cardiac valve prosthesis with valve flaps of biological tissues |
EP0179562B1 (en) * | 1984-09-28 | 1989-07-12 | The University of Glasgow, University Court | A heart valve prosthesis |
Cited By (118)
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US5449385A (en) * | 1991-05-08 | 1995-09-12 | Nika Health Products Limited | Support for a heart valve prosthesis |
US6129758A (en) * | 1995-10-06 | 2000-10-10 | Cardiomend Llc | Products and methods for circulatory system valve repair |
US5716399A (en) * | 1995-10-06 | 1998-02-10 | Cardiomend Llc | Methods of heart valve repair |
US6102944A (en) * | 1997-03-27 | 2000-08-15 | Edwards Lifesciences Corporation | Methods of tissue heart valve assembly |
US6585766B1 (en) | 1997-03-27 | 2003-07-01 | Edwards Lifesciences Corporation | Cloth-covered stents for tissue heart valves |
US6945997B2 (en) | 1997-03-27 | 2005-09-20 | Edwards Lifesciences Corporation | Heart valves and suture rings therefor |
US8518108B2 (en) | 1997-03-27 | 2013-08-27 | Edwards Lifesciences Corporation | Contoured heart valve suture rings |
US6598307B2 (en) | 1999-11-17 | 2003-07-29 | Jack W. Love | Device and method for assessing the geometry of a heart valve |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US6869444B2 (en) * | 2000-05-22 | 2005-03-22 | Shlomo Gabbay | Low invasive implantable cardiac prosthesis and method for helping improve operation of a heart valve |
US9439762B2 (en) | 2000-06-01 | 2016-09-13 | Edwards Lifesciences Corporation | Methods of implant of a heart valve with a convertible sewing ring |
US10238486B2 (en) | 2000-06-01 | 2019-03-26 | Edwards Lifesciences Corporation | Heart valve with integrated stent and sewing ring |
US6425902B1 (en) | 2001-05-04 | 2002-07-30 | Cardiomend Llc | Surgical instrument for heart valve reconstruction |
US11166810B2 (en) | 2001-10-11 | 2021-11-09 | Edwards Lifesciences Pvt, Inc. | Implantable prosthetic valve |
US10052203B2 (en) | 2001-10-11 | 2018-08-21 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9937039B2 (en) | 2001-10-11 | 2018-04-10 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9629717B2 (en) | 2001-10-11 | 2017-04-25 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US11123182B2 (en) | 2001-10-11 | 2021-09-21 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US10595991B2 (en) | 2002-12-20 | 2020-03-24 | Medtronic, Inc. | Heart valve assemblies |
US8460373B2 (en) | 2002-12-20 | 2013-06-11 | Medtronic, Inc. | Method for implanting a heart valve within an annulus of a patient |
US9333078B2 (en) | 2002-12-20 | 2016-05-10 | Medtronic, Inc. | Heart valve assemblies |
US8747463B2 (en) | 2003-08-22 | 2014-06-10 | Medtronic, Inc. | Methods of using a prosthesis fixturing device |
US9155617B2 (en) | 2004-01-23 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic mitral valve |
US10085836B2 (en) | 2004-01-23 | 2018-10-02 | Edwards Lifesciences Corporation | Prosthetic mitral valve |
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US10231646B2 (en) | 2009-10-27 | 2019-03-19 | Edwards Lifesciences Corporation | Device for measuring an aortic valve annulus in an expanded condition |
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Also Published As
Publication number | Publication date |
---|---|
CA2080138A1 (en) | 1992-08-08 |
ES2028611A6 (en) | 1992-07-01 |
AU1261292A (en) | 1992-09-07 |
EP0532719A1 (en) | 1993-03-24 |
BR9204120A (en) | 1993-06-08 |
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