WO1992021327A1 - Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same - Google Patents
Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same Download PDFInfo
- Publication number
- WO1992021327A1 WO1992021327A1 PCT/US1992/004265 US9204265W WO9221327A1 WO 1992021327 A1 WO1992021327 A1 WO 1992021327A1 US 9204265 W US9204265 W US 9204265W WO 9221327 A1 WO9221327 A1 WO 9221327A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- monomer
- microspheres
- microsphere
- weight
- cell adhesion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU20168/92A AU661319B2 (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
US08/150,148 US5635215A (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
JP50046193A JP3509858B2 (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusion and injection solutions containing them |
CA002110290A CA2110290C (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
EP92911942A EP0588875B1 (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
DE69218938T DE69218938T2 (en) | 1991-05-29 | 1992-05-20 | MICROBALLS FOR THERAPEUTIC VASCULAR CAPS AND INJECTION SOLUTIONS CONTAINING THEM |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR91/06441 | 1991-05-29 | ||
FR9106441A FR2676927B1 (en) | 1991-05-29 | 1991-05-29 | MICROSPHERES FOR USE IN THERAPEUTIC VASCULAR OCCLUSIONS AND INJECTABLE SOLUTIONS CONTAINING THEM. |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1992021327A1 true WO1992021327A1 (en) | 1992-12-10 |
Family
ID=9413226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1992/004265 WO1992021327A1 (en) | 1991-05-29 | 1992-05-20 | Microspheres useful for therapeutic vascular occlusions and injectable solutions containing the same |
Country Status (11)
Country | Link |
---|---|
US (2) | US5635215A (en) |
EP (1) | EP0588875B1 (en) |
JP (1) | JP3509858B2 (en) |
AT (1) | ATE151284T1 (en) |
AU (1) | AU661319B2 (en) |
CA (1) | CA2110290C (en) |
DE (1) | DE69218938T2 (en) |
DK (1) | DK0588875T3 (en) |
ES (1) | ES2099827T3 (en) |
FR (1) | FR2676927B1 (en) |
WO (1) | WO1992021327A1 (en) |
Cited By (19)
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US6660301B1 (en) | 1998-03-06 | 2003-12-09 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
US6676971B2 (en) | 2000-03-13 | 2004-01-13 | Biocure, Inc. | Embolic compositions |
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US7070809B2 (en) | 2000-03-13 | 2006-07-04 | Biocure, Inc. | Hydrogel biomedical articles |
US20110182998A1 (en) * | 2010-01-27 | 2011-07-28 | Biosphere Medical, Inc. | Microspheres useful for therapeutic vascular embolization |
US8778333B2 (en) | 2000-03-20 | 2014-07-15 | Biosphere Medical, Inc. | Injectable microspheres for tissue construction |
US8932637B2 (en) | 2000-03-20 | 2015-01-13 | Biosphere Medical. Inc. | Injectable and swellable microspheres for tissue bulking |
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US20050049178A1 (en) * | 1999-07-06 | 2005-03-03 | Oberschwabenklinik Gmbh | Agent for the occlusion of blood vessels |
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US6855160B1 (en) | 1999-08-04 | 2005-02-15 | C. R. Bard, Inc. | Implant and agent delivery device |
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US20030212022A1 (en) * | 2001-03-23 | 2003-11-13 | Jean-Marie Vogel | Compositions and methods for gene therapy |
US7232421B1 (en) | 2000-05-12 | 2007-06-19 | C. R. Bard, Inc. | Agent delivery systems |
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US4622362A (en) * | 1981-03-30 | 1986-11-11 | California Institute Of Technology | Polyacrolein microspheres |
US4413070A (en) * | 1981-03-30 | 1983-11-01 | California Institute Of Technology | Polyacrolein microspheres |
-
1991
- 1991-05-29 FR FR9106441A patent/FR2676927B1/en not_active Expired - Lifetime
-
1992
- 1992-05-20 EP EP92911942A patent/EP0588875B1/en not_active Expired - Lifetime
- 1992-05-20 AU AU20168/92A patent/AU661319B2/en not_active Expired
- 1992-05-20 AT AT92911942T patent/ATE151284T1/en active
- 1992-05-20 CA CA002110290A patent/CA2110290C/en not_active Expired - Lifetime
- 1992-05-20 WO PCT/US1992/004265 patent/WO1992021327A1/en active IP Right Grant
- 1992-05-20 US US08/150,148 patent/US5635215A/en not_active Expired - Lifetime
- 1992-05-20 DE DE69218938T patent/DE69218938T2/en not_active Expired - Lifetime
- 1992-05-20 DK DK92911942.8T patent/DK0588875T3/en active
- 1992-05-20 ES ES92911942T patent/ES2099827T3/en not_active Expired - Lifetime
- 1992-05-20 JP JP50046193A patent/JP3509858B2/en not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/471,303 patent/US5648100A/en not_active Expired - Lifetime
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US3797485A (en) * | 1971-03-26 | 1974-03-19 | Alza Corp | Novel drug delivery device for administering drug into blood circulation in blood vessel |
US4536387A (en) * | 1982-02-12 | 1985-08-20 | Unitika Ltd. | Anti-cancer device |
US4801458A (en) * | 1985-06-24 | 1989-01-31 | Teijin Limited | Sustained release pharmaceutical plaster |
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Cited By (49)
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DE4341478C2 (en) * | 1993-12-02 | 1998-10-08 | Max Delbrueck Centrum | Antitumor therapy agents |
DE4341478A1 (en) * | 1993-12-02 | 1995-06-08 | Max Delbrueck Centrum | Antitumour compsn. comprising starch particles, cytostatic and contrast agent |
US7060298B2 (en) | 1998-03-06 | 2006-06-13 | Biosphere Medical, Inc. | Implantable particles for the treatment of gastroesophageal reflux disease |
WO1999044643A1 (en) * | 1998-03-06 | 1999-09-10 | Biosepra Medical Inc. | Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles |
US9295648B2 (en) | 1998-03-06 | 2016-03-29 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
US6335028B1 (en) | 1998-03-06 | 2002-01-01 | Biosphere Medical, Inc. | Implantable particles for urinary incontinence |
US9205053B2 (en) | 1998-03-06 | 2015-12-08 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
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Also Published As
Publication number | Publication date |
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AU2016892A (en) | 1993-01-08 |
DK0588875T3 (en) | 1997-04-28 |
JPH06508139A (en) | 1994-09-14 |
FR2676927A1 (en) | 1992-12-04 |
ATE151284T1 (en) | 1997-04-15 |
EP0588875B1 (en) | 1997-04-09 |
DE69218938D1 (en) | 1997-05-15 |
US5648100A (en) | 1997-07-15 |
CA2110290A1 (en) | 1992-12-10 |
US5635215A (en) | 1997-06-03 |
EP0588875A4 (en) | 1994-08-03 |
JP3509858B2 (en) | 2004-03-22 |
AU661319B2 (en) | 1995-07-20 |
FR2676927B1 (en) | 1995-06-23 |
EP0588875A1 (en) | 1994-03-30 |
CA2110290C (en) | 2002-02-05 |
DE69218938T2 (en) | 1997-07-31 |
ES2099827T3 (en) | 1997-06-01 |
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