WO1993022987A3 - Gel composition for implant and method - Google Patents

Gel composition for implant and method Download PDF

Info

Publication number
WO1993022987A3
WO1993022987A3 PCT/US1993/004748 US9304748W WO9322987A3 WO 1993022987 A3 WO1993022987 A3 WO 1993022987A3 US 9304748 W US9304748 W US 9304748W WO 9322987 A3 WO9322987 A3 WO 9322987A3
Authority
WO
WIPO (PCT)
Prior art keywords
implant
gel composition
composition
prostheses
fillers
Prior art date
Application number
PCT/US1993/004748
Other languages
French (fr)
Other versions
WO1993022987A2 (en
Inventor
Daiva Kristina Tautvydas
Mannarsamy Balasubramanian
R Martin Emanuele
Original Assignee
Cytrx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytrx Corp filed Critical Cytrx Corp
Publication of WO1993022987A2 publication Critical patent/WO1993022987A2/en
Publication of WO1993022987A3 publication Critical patent/WO1993022987A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00902Material properties transparent or translucent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/12Mammary prostheses and implants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924Material characteristic

Abstract

In accordance with the present invention, a composition and method is provided for a biocompatible filler for prostheses. The composition and method relate to certain polyoxyethylene/polyoxypropylene block copolymers which have gelling properties at body temperature and are ideally suited for use as fillers for a soft tissue prosthesis such as a breast implant.
PCT/US1993/004748 1992-05-20 1993-05-19 Gel composition for implant and method WO1993022987A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88626492A 1992-05-20 1992-05-20
US886,264 1992-05-20

Publications (2)

Publication Number Publication Date
WO1993022987A2 WO1993022987A2 (en) 1993-11-25
WO1993022987A3 true WO1993022987A3 (en) 1994-01-20

Family

ID=25388732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/004748 WO1993022987A2 (en) 1992-05-20 1993-05-19 Gel composition for implant and method

Country Status (3)

Country Link
US (1) US5407445A (en)
AU (1) AU4381793A (en)
WO (1) WO1993022987A2 (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117176A (en) * 1993-11-15 2000-09-12 Applied Elastomerics, Inc. Elastic-crystal gel
US5634943A (en) * 1990-07-12 1997-06-03 University Of Miami Injectable polyethylene oxide gel implant and method for production
US6251137B1 (en) 1994-03-23 2001-06-26 Mcghan Medical Corporation Synthetic triglyceride filler material for surgically implanted prostheses
US6290723B1 (en) 1994-06-14 2001-09-18 Winston A. Andrews Method of making a synthetic triglyceride filler material
US5632774A (en) * 1995-01-17 1997-05-27 Babian; Hamik In-the-shell hydration to make implant filler material and prosthesis employing same
US5941909A (en) * 1995-02-14 1999-08-24 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
US5658329A (en) * 1995-02-14 1997-08-19 Mentor Corporation Filling material for soft tissue implant prostheses and implants made therewith
JPH11501847A (en) * 1995-03-15 1999-02-16 アクシュネット カンパニー Flexible shoe structure and gel composition for the structure
US5955159A (en) * 1995-03-15 1999-09-21 Acushnet Company Conforming shoe construction using gels and method of making the same
US5939157A (en) * 1995-10-30 1999-08-17 Acushnet Company Conforming shoe construction using gels and method of making the same
US5985383A (en) * 1995-03-15 1999-11-16 Acushnet Company Conforming shoe construction and gel compositions therefor
US6312466B1 (en) * 1995-05-22 2001-11-06 Board Of Regents, University Of Texas System Prosthesis containing a solution of polyethylene glycol
US5662708A (en) * 1995-08-08 1997-09-02 Novamed Medical Products Manufacturing, Inc. Rheologically modified and osmotically balanced fill material for implant
US5766704A (en) * 1995-10-27 1998-06-16 Acushnet Company Conforming shoe construction and gel compositions therefor
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
WO1998032433A1 (en) * 1997-01-24 1998-07-30 Medlogic Global Corporation Conformable structures
US6443986B1 (en) 1998-03-12 2002-09-03 Coloplast Corp Self-forming prosthetic device and method of making the same
AU2904999A (en) * 1998-03-12 1999-09-27 Coloplast Corporation Self-forming partial breast prosthesis and a method of making the same
DE69922050T2 (en) * 1999-02-05 2005-11-10 The Regents Of The University Of California, Oakland THERMOREVERSIBLES POLYMER FOR INTRALUMENAL IMPLANTS
US6974480B2 (en) 2001-05-03 2005-12-13 Synthes (Usa) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US6719794B2 (en) * 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
GB0116341D0 (en) * 2001-07-04 2001-08-29 Smith & Nephew Biodegradable polymer systems
GB0202233D0 (en) * 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
AU2003261651A1 (en) * 2002-09-09 2004-03-29 Hb Medicals Corporation Novel implantable artificial breast silicon shell
EP1596765A2 (en) * 2003-02-10 2005-11-23 Smith & Nephew, Inc. Resorbable devices
US20040241200A1 (en) * 2003-05-19 2004-12-02 Daniel Winn Personal care products that do not contain tetramer and/or pentamer cyclomethicones
GB0317192D0 (en) * 2003-07-19 2003-08-27 Smith & Nephew High strength bioresorbable co-polymers
GB0329654D0 (en) * 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US7951880B2 (en) * 2004-12-10 2011-05-31 University Of Iowa Research Foundation Compositions for breast implant filling and methods of use
DK1877002T3 (en) 2005-04-25 2013-05-27 G & G Biotechnology Ltd LIGHT WEIGHT IMPLANT PORTABLE DEVICE
CA2619571A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
US8062282B2 (en) * 2006-02-13 2011-11-22 Fossa Medical, Inc. Methods and apparatus for temporarily occluding body openings
WO2007103276A2 (en) 2006-03-03 2007-09-13 Smith & Nephew, Inc. Systems and methods for delivering a medicament
BRPI0622149A2 (en) * 2006-10-10 2014-07-08 Aortech Biomaterials Pty Ltd SOFT FABRIC IMPLANT
CN101594831B (en) * 2006-11-30 2011-09-14 史密夫和内修有限公司 Fiber reinforced composite material
JP5416090B2 (en) * 2007-04-18 2014-02-12 スミス アンド ネフュー ピーエルシー Expansion molding of shape memory polymer
DE602008006181D1 (en) * 2007-04-19 2011-05-26 Smith & Nephew Inc GRAFT FIXATION
EP2142227B1 (en) 2007-04-19 2012-02-29 Smith & Nephew, Inc. Multi-modal shape memory polymers
US20090157180A1 (en) * 2007-12-18 2009-06-18 Steven Schraga Medical implant containing detection enhancing agent and method for detecting content leakage
EP2641566A1 (en) * 2008-06-30 2013-09-25 Allergan, Inc. Fillable prosthetic implant with gel-like properties
US20100100115A1 (en) * 2008-10-20 2010-04-22 Wilson-Cook Medical Inc. Foam filled intragastric balloon for treating obesity
US9339371B2 (en) 2010-01-18 2016-05-17 G & G Biotechnology Ltd Lightweight breast implant material
WO2014191523A2 (en) * 2013-05-29 2014-12-04 Therakine Biodelivery Gmbh Hydrophilic microparticles, drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
BR112017019431B1 (en) 2015-03-12 2022-11-08 G & G Biotechnology Ltd PROTEIN IMPLANT WITH A COMPOSITE OF A BASE MATERIAL AND AN ADDITIVE MATERIAL

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4995882A (en) * 1989-08-28 1991-02-26 Washington University Radiolucent breast implant
US5120816A (en) * 1987-12-02 1992-06-09 Tyndale Plains-Hunter Ltd. Hydrophilic polyurethanes of improved strength

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3293663A (en) * 1963-08-12 1966-12-27 Dow Corning Surgically implantable human breast prosthesis
US3683424A (en) * 1970-01-30 1972-08-15 William J Pangman Surgically implantable compound breast prosthesis
US3665520A (en) * 1970-10-07 1972-05-30 Medical Eng Corp Surgically implantable breast prosthesis
US3681787A (en) * 1971-03-26 1972-08-08 Moxness Products Inc Implantable breast prosthesis filled with gels of different densities
US3919724A (en) * 1974-06-07 1975-11-18 Medical Eng Corp Implantable prosthesis having a self-sealing valve
US4143428A (en) * 1976-12-16 1979-03-13 Cohen I Kelman Saline fill of silicone prosthesis during mammaplasty augmentation
US4095295A (en) * 1977-03-28 1978-06-20 Douglas Lake Adjustable, fluid-filled breast implant
GB2041377B (en) * 1979-01-22 1983-09-28 Woodroof Lab Inc Bio compatible and blood compatible materials and methods
SE426908B (en) * 1979-02-19 1983-02-21 Polar Plastik Hb BROWN IMPLANT PROVIDED TO BE OPERATED UNDER THE FEMALE BROWN
US4433440A (en) * 1979-02-26 1984-02-28 Cohen I Kelman Prosthesis formed by inner and outer inflatable containers
US4298997A (en) * 1979-10-23 1981-11-10 Rybka F James Device for inhibiting the formation of fibrous capsular contractures in silicone breast implants and method
US4650487A (en) * 1980-10-27 1987-03-17 Memorial Hospital For Cancer And Allied Diseases Multi-lumen high profile mammary implant
US4740208A (en) * 1980-11-21 1988-04-26 Cavon Joseph F Cast gel implantable prosthesis
US4840628A (en) * 1980-11-21 1989-06-20 Cavon Joseph F Non-enveloped gel prosthesis
US4298998A (en) * 1980-12-08 1981-11-10 Naficy Sadeque S Breast prosthesis with biologically absorbable outer container
US4773909A (en) * 1981-10-06 1988-09-27 Memorial Hospital For Cancer And Allied Diseases Multi-lumen high profile mammary implant
US4820302A (en) * 1982-04-22 1989-04-11 Sterling Drug Inc. Bio compatible and blood compatible materials and methods
US4610690A (en) * 1983-02-22 1986-09-09 Mentor Corporation Rupture resistant prosthesis with bonded surface layer and method of forming same
DE3329733A1 (en) * 1983-08-17 1985-03-07 Johannes Dr.med. 6500 Mainz Reinmüller PLASTIC IMPLANT
US4573999A (en) * 1983-10-14 1986-03-04 Netto Daniel J Human breast prosthesis
US4772285A (en) * 1984-05-09 1988-09-20 The Board Of Trustees Of The Leland Stanford Junior University Collagen coated soft tissue prostheses
GB8418772D0 (en) * 1984-07-24 1984-08-30 Geistlich Soehne Ag Chemical substances
US4648880A (en) * 1984-08-30 1987-03-10 Daniel Brauman Implantable prosthetic devices
US4963150B1 (en) * 1984-08-30 1994-10-04 Daniel Brauman Implantable prosthetic device
US4820303A (en) * 1984-08-30 1989-04-11 Daniel Brauman Implantable prosthetic devices
US4731081A (en) * 1984-09-11 1988-03-15 Mentor Corporation Rupture-resistant prosthesis with creasable shell and method of forming same
US4795463A (en) * 1984-10-03 1989-01-03 Baylor College Of Medicine Labeled breast prosthesis and methods for detecting and predicting rupture of the prosthesis
US4636213A (en) * 1985-01-24 1987-01-13 Pakiam Anthony I Implantable prosthesis
US4769036A (en) * 1985-07-17 1988-09-06 Jamal Modir Reconstructive mammary prosthesis
US4702917A (en) * 1985-11-18 1987-10-27 Research Triangle Institute Porous bioabsorbable polyesters
US4772284A (en) * 1986-03-27 1988-09-20 Collagenix Corporation Breast prosthesis with improved biocompatibility and method of making the same
AU593267B2 (en) * 1986-07-22 1990-02-08 Paul O'keeffe Implantable fabric pouch for mammary prothesis
US4822741A (en) * 1987-05-04 1989-04-18 Banes Albert J Biocompatible polyorganosiloxane composition for cell culture apparatus
US4839280A (en) * 1987-05-04 1989-06-13 Banes Albert J Apparatus for applying stress to cell cultures
NL8701548A (en) * 1987-07-01 1989-02-01 Tno POLYMER NETWORK, METHOD FOR THE PREPARATION THEREOF, THE USE THEREOF FOR CLADING AND / OR IMPREGNATING OR FOR MANUFACTURING EYE LENSES, AND FORMED PROPERTIES, WHOLLY OR FROM AN EXISTINGLY PROVEN POLISH.
US4912141A (en) * 1987-07-28 1990-03-27 Kronman Joseph H Fibrous and cartilaginous tissue replacement
US4902511A (en) * 1987-07-28 1990-02-20 Kronman Joseph H Fibrous and cartilaginous tissue replacement
US4790848A (en) * 1987-11-27 1988-12-13 Dow Corning Wright Breast prosthesis with multiple lumens
US4955909A (en) * 1989-01-31 1990-09-11 Bioplasty, Inc. Textured silicone implant prosthesis
US5067965A (en) * 1990-03-20 1991-11-26 Bioplasty, Inc. Bio-osmotic gel for implant prostheses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120816A (en) * 1987-12-02 1992-06-09 Tyndale Plains-Hunter Ltd. Hydrophilic polyurethanes of improved strength
US4995882A (en) * 1989-08-28 1991-02-26 Washington University Radiolucent breast implant

Also Published As

Publication number Publication date
AU4381793A (en) 1993-12-13
WO1993022987A2 (en) 1993-11-25
US5407445A (en) 1995-04-18

Similar Documents

Publication Publication Date Title
WO1993022987A3 (en) Gel composition for implant and method
EP0895785A3 (en) Filling material for soft tissue implant prostheses and implants made therewith
BR9407419A (en) Improved soft tissue implant
AU2676795A (en) Soft implantable surgical prosthesis for increasing or restoring the volume of soft tissues, in particular a breast prosthesis and method of manufacture
AU3677793A (en) Gel-filled implants
HK1012588A1 (en) Filling material for soft tissue implant prostheses and implants made therewith
IL124798A0 (en) Bioactive load bearing bone bonding compositions
DE3378303D1 (en) Polymeric acrylic prosthesis
CA2057277A1 (en) Biodegradable biocompatible anti-displacement device for prosthetic bone joints
AUPO185796A0 (en) Ocular socket prosthesis
CA2104231A1 (en) Oblong acetabular cup
CA2158638A1 (en) A Composition and a Method for Tissue Augmentation
WO2002039889A3 (en) Implantable orthopedic support apparatus and method for making same
CA2183263A1 (en) Improved process for fixation of calcification-resistant biological tissue
CA2446573A1 (en) Surgical implant containing a resorbable radiopaque marker
DE69531859D1 (en) Bioumbaubare collagentransplantat prothese
DK333184D0 (en) DENTAL IMPLANTATION BODY
CA2138270A1 (en) Prosthetic Devices Having Enhanced Osteogenic Properties
UA56989C2 (en) PHYSIOLOGICALLY ACTIVE PEG-CONJUGATE OF a-INTERFERON, A METHOD FOR PREPARING THE SAME, A PHARMACEUTICAL COMPOSITION BASED THEREON AND A METHOD FOR TREATMENT OR PROPHYLAXIS OF IMMUNOMODULAR DISEASES
CA2057044A1 (en) Bio-osmotic gel for implant protheses
GR3034761T3 (en) Methods of enhancing wound healing and tissue repair.
Duman et al. Reconstruction of contour and anterior wall defects of frontal bone with a porous polyethylene implant
AU5960201A (en) Supplementary endo-capsular lens and method of implantation
AU6697100A (en) A device for dental implantation
GB2246957B (en) Artificial acetabular implants,artificial hip joint,and parts thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AT AU BB BG BR CA CH CZ DE DK ES FI GB HU JP KP KR LK LU MG MN MW NL NO NZ PL PT RO RU SD SE SK UA VN

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AT AU BB BG BR CA CH CZ DE DK ES FI GB HU JP KP KR LK LU MG MN MW NL NO NZ PL PT RO RU SD SE SK UA VN

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: CA

122 Ep: pct application non-entry in european phase