WO1994019043A1 - Medicament presentation - Google Patents

Medicament presentation Download PDF

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Publication number
WO1994019043A1
WO1994019043A1 PCT/EP1994/000513 EP9400513W WO9419043A1 WO 1994019043 A1 WO1994019043 A1 WO 1994019043A1 EP 9400513 W EP9400513 W EP 9400513W WO 9419043 A1 WO9419043 A1 WO 9419043A1
Authority
WO
WIPO (PCT)
Prior art keywords
inner container
medicament
vapour
dispenser
liquid
Prior art date
Application number
PCT/EP1994/000513
Other languages
French (fr)
Inventor
Nigel Colin Theobald
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Priority to AU62048/94A priority Critical patent/AU6204894A/en
Publication of WO1994019043A1 publication Critical patent/WO1994019043A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/54—Cards, coupons, or other inserts or accessories
    • B65D75/56—Handles or other suspension means
    • B65D75/563—Integral handles or suspension means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/38—Articles or materials enclosed in two or more wrappers disposed one inside the other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/52—Details
    • B65D2575/54—Cards, coupons, or other inserts or accessories
    • B65D2575/56—Handles or other suspension means
    • B65D2575/565—Handles or other suspension means means explicitly used for suspending

Definitions

  • the present invention relates to means for presentation of medicaments, in particular to a form of packaging and dispensing volatile liquid medicaments such as decongestant inhalation products.
  • Decongestant inhalation products are highly volatile at room temperature. They are designed to be applied to a fabric substrate such as bed clothes or * the clothing of the wearer prior to use so the volatile aromatic vapour produced can be inhaled by the user over a length of time.
  • a fabric substrate such as bed clothes or * the clothing of the wearer prior to use so the volatile aromatic vapour produced can be inhaled by the user over a length of time.
  • medicaments are often sticky, and messy to apply to a fabric substrate. It would be advantageous to present the medicament in a form which allows slow release of vapour without the need to soil bed clothes or the like with the medicament.
  • the present invention provides a dispenser for administering a volatile liquid medicament comprising an inner container adapted to hold the liquid medicament, said inner container being permeable to vapour from the medicament, but substantially impermeable to the liquid medicament, and an outer container within which the first retaining means has been sealed, the outer container being impermeable to the medicament as liquid or vapour.
  • the dispenser comprises an absorbent solid substrate within the inner container onto which the liquid medicament is absorbed.
  • the absorbent solid may be a woven or non-woven fabric, a synthetic or natural sponge, a foamed plastics material or paper, preferably tissue paper.
  • the inner container comprises a semi- permeable membrane over all or a portion of its surface.
  • the inner container may comprise a plastics material impermeable to aromatic liquids [e.g. polyvinylchloride (PVC) or a polyolefin] which is microperforated to allow passage of the vapour.
  • PVC polyvinylchloride
  • polyolefin polyolefin
  • the outer container preferably comprises a plastics material which may be a single material which is impermeable to the vapour of the volatile medicament, or it may comprise a composite of (a) a supporting layer of a plastics material which may on its own be permeable to the vapour but which has sufficient strength to protect the dispenser during manufacture, transport and display and (b) a layer or coating of a material which is impermeable to the vapour of the volatile medicament on the surface of the supporting layer which forms the inner surface of the outer container.
  • the supporting layer may be a polyolefin homopolymer or copolymer or a polyvinylchloride homopolymer or copolymer.
  • the impermeable layer may be formed by laminating a separate layer of impermeable material such as a plastics material (e.g. polyvinylidenechloride polymer) or metal (e.g. an aluminium) film to the supporting layer or by coating the supporting layer with an impermeable coating e.g of polyvinylidenechloride polymer, aluminium, aluminium oxide or silicon oxide.
  • a plastics material e.g. polyvinylidenechloride polymer
  • metal e.g. an aluminium
  • an impermeable coating e.g of polyvinylidenechloride polymer, aluminium, aluminium oxide or silicon oxide.
  • the material from which the outer container is made is one which can be sealed to itself by the application of heat or high frequency welding.
  • the outer container is manufactured from two sheets which are sealed together around their periphery either by heat sealing or by the use of adhesive to enclose the inner container.
  • the outer container is formed by a backing member of a rigid plastics material which is impermeable to the liquid medicament and to the vapour thereof and a vapour- impermeable film sealed to the backing member enclosing the inner container.
  • the inner container may also be formed by the backing member and a liquid-medicament- impermeable film sealed to the backing member to enclose either the liquid medicament or a substrate impregnated with the liquid medicament.
  • the medicament may comprise any liquid medicament which is volatile at room temperature, more preferably a decongestant inhalation product used for treating the symptoms of cold or flu, most preferably the medicament is an aromatic mixture of essential oils and spices such as pine oil, cinnamon oil and menthol for example that available from the applicant under the trade mark Karvol.
  • a decongestant inhalation product used for treating the symptoms of cold or flu
  • the medicament is an aromatic mixture of essential oils and spices such as pine oil, cinnamon oil and menthol for example that available from the applicant under the trade mark Karvol.
  • the single dose of liquid medicament is from about 0.1 ml to about 5 ml, more preferably from about 0.5 ml to about 2 ml, most preferably about 1 ml.
  • the medicament presentation of the present invention may be useful for other volatile liquid medicaments that are staining, are irritating to the skin, or noxious in some other way, the vapour of which is nevertheless therapeutic.
  • the inner container may further comprise a means for attaching the inner container to an object.
  • the attaching means may be an adhesive means such as an adhesive patch located on the outer surface of the inner container for attachment of the pack to a surface.
  • the attaching means may be an engagement means mounted on or integral to the inner container such as a hook shaped portion of the inner container.
  • the backing member may be shaped, for example as a hook to provide the attachment means.
  • the attachment means provides a means to locate the dispenser near to the patient for example by attachment to the bed or cot rail so that the medicament vapour diffuses slowly from the inner container.
  • the medicament vapour can be inhaled by the patient for example when asleep to provide a long lasting effect.
  • a further advantage of the pack of the present invention is that the rate of diffusion of the medicament vapour from the pack may be controlled by the nature of the absorbent substrate and permeability of the inner container.
  • the dispensers of the present invention may be manufactured by impregnating a solid substrate with the liquid medicament and sealing the impregnated substrate inside the inner container.
  • the impregnated substrate may be placed between two sheets of a plastics material which is impermeable to the liquid medicament and the sheets sealed around their periphery to enclose the substrate inside the inner container. At least one of the sheets should be permeable to the vapour of the medicament.
  • the substrate may be placed inside a pouch of a vapour-permeable plastics material which is subsequently sealed at its open end to enclose the substrate.
  • the substrate may be impregnated before it is placed inside the pouch or after the substrate has been inserted.
  • the liquid medicament may be placed in the pouch prior to the insertion of the substrate.
  • the impregnated substrate inside the inner container is then placed inside the outer container.
  • the outer container may be formed from two sheets of plastics material which are sealed around their periphery or it may be a pouch sealed on three sides into which the inner container is placed prior to sealing the outer container.
  • the dispenser may be assembled by placing a substrate impregnated with the liquid medicament on the backing member, placing a film of vapour-permeable material over the substrate and sealing that film to the backing member around its periphery to form an inner container and then placing a film of vapour-impermeable material over the inner container and sealing it around its periphery to the backing member.
  • the outer container prevents leakage of either vapour or liquid medicament.
  • the outer container is opened, which allows the medicament vapour to diffuse slowly through the inner container, to be inhaled by the user.
  • the medicament liquid remains within the inner container absorbed onto the substrate.
  • Figure 1 is a plan view of a first embodiment of the present invention
  • Figure 2 is a cross-sectional view of a second embodiment of the present invention
  • Figure 3 is a plan view of the second embodiment shown in Figure 2.
  • the dispenser shown in Figure 1 contains a single dose of a Karvol (RTM) liquid decongestant inhalation product.
  • the impregnated substrate is located between two sheets 2,3 of a microperforated plastics material which are sealed together around their periphery, for example by heat sealing, to form an inner container enclosing the impregnated substrate.
  • the inner container is then placed between two sheets 4,5 of material which are impermeable to the vapour of the medicament and which are sealed around their periphery to prevent any loss of medicament vapour until the seal is broken by the user.
  • the sealing may be performed by heat sealing or radio frequency welding. If the sheets have a coating or film of aluminium then the sealing must be performed by the use of an adhesive. To use the dispenser, the seal of the outer container is broken and the inner container is removed. This allows the volatile, aromatic Karvol (RTM) vapour to diffuse slowly from the inner container to be inhaled by the user.
  • RTM volatile, aromatic Karvol
  • a substrate 11 impregnated with a volatile liquid medicament is located on a backing member 10 which is made of a material which is impervious to the liquid medicament and to the vapour of the medicament.
  • the backing member 10 is made from a rigid plastics material.
  • the impregnated substrate 11 is retained in position by a vapour permeable film 12 which is sealed around its periphery to the backing member 10 by a seal 13.
  • a further film 14 of vapour impermeable material is sealed to the backing member 10 by a peripheral seal 15 which is located outside the seal 13.
  • the further film may be provided with areas of weakness
  • the seal 15 may be such that the further film 14 can be removed from the backing member
  • the backing member 10 is shaped in the form of a hook 16 to enable the dispenser to be hung near the patient for example on the rail of a child's cot.

Abstract

A dispenser for administering a volatile liquid medicament comprises an inner container (2, 3) adapted to hold the liquid medicament (1), said inner container (2, 3) being permeable to vapour from the medicament (1), but substantially impermeable to the liquid medicament (1), and an outer container (4, 5) within which the first retaining means (2, 3), has been sealed, the outer container (4, 5) being impermeable to the medicament (1) as liquid or vapour.

Description

MEDICAMENT PRESENTATION
The present invention relates to means for presentation of medicaments, in particular to a form of packaging and dispensing volatile liquid medicaments such as decongestant inhalation products.
Decongestant inhalation products (for example those available commercially under the registered trademark Karvol) are highly volatile at room temperature. They are designed to be applied to a fabric substrate such as bed clothes or* the clothing of the wearer prior to use so the volatile aromatic vapour produced can be inhaled by the user over a length of time. However, such medicaments are often sticky, and messy to apply to a fabric substrate. It would be advantageous to present the medicament in a form which allows slow release of vapour without the need to soil bed clothes or the like with the medicament.
The present invention provides a dispenser for administering a volatile liquid medicament comprising an inner container adapted to hold the liquid medicament, said inner container being permeable to vapour from the medicament, but substantially impermeable to the liquid medicament, and an outer container within which the first retaining means has been sealed, the outer container being impermeable to the medicament as liquid or vapour.
Preferably the dispenser comprises an absorbent solid substrate within the inner container onto which the liquid medicament is absorbed. The absorbent solid may be a woven or non-woven fabric, a synthetic or natural sponge, a foamed plastics material or paper, preferably tissue paper.
Preferably the inner container comprises a semi- permeable membrane over all or a portion of its surface. The inner container may comprise a plastics material impermeable to aromatic liquids [e.g. polyvinylchloride (PVC) or a polyolefin] which is microperforated to allow passage of the vapour.
The outer container preferably comprises a plastics material which may be a single material which is impermeable to the vapour of the volatile medicament, or it may comprise a composite of (a) a supporting layer of a plastics material which may on its own be permeable to the vapour but which has sufficient strength to protect the dispenser during manufacture, transport and display and (b) a layer or coating of a material which is impermeable to the vapour of the volatile medicament on the surface of the supporting layer which forms the inner surface of the outer container. The supporting layer may be a polyolefin homopolymer or copolymer or a polyvinylchloride homopolymer or copolymer. The impermeable layer may be formed by laminating a separate layer of impermeable material such as a plastics material (e.g. polyvinylidenechloride polymer) or metal (e.g. an aluminium) film to the supporting layer or by coating the supporting layer with an impermeable coating e.g of polyvinylidenechloride polymer, aluminium, aluminium oxide or silicon oxide. Preferably the material from which the outer container is made is one which can be sealed to itself by the application of heat or high frequency welding. In one preferred embodiment the outer container is manufactured from two sheets which are sealed together around their periphery either by heat sealing or by the use of adhesive to enclose the inner container. In another embodiment, the outer container is formed by a backing member of a rigid plastics material which is impermeable to the liquid medicament and to the vapour thereof and a vapour- impermeable film sealed to the backing member enclosing the inner container. The inner container may also be formed by the backing member and a liquid-medicament- impermeable film sealed to the backing member to enclose either the liquid medicament or a substrate impregnated with the liquid medicament.
The medicament may comprise any liquid medicament which is volatile at room temperature, more preferably a decongestant inhalation product used for treating the symptoms of cold or flu, most preferably the medicament is an aromatic mixture of essential oils and spices such as pine oil, cinnamon oil and menthol for example that available from the applicant under the trade mark Karvol.
Preferably the single dose of liquid medicament is from about 0.1 ml to about 5 ml, more preferably from about 0.5 ml to about 2 ml, most preferably about 1 ml.
As well as being useful for decongestant inhalation products the medicament presentation of the present invention may be useful for other volatile liquid medicaments that are staining, are irritating to the skin, or noxious in some other way, the vapour of which is nevertheless therapeutic.
Where the inner container of the dispenser of the invention is removed from the outer container before use, the inner container may further comprise a means for attaching the inner container to an object. The attaching means may be an adhesive means such as an adhesive patch located on the outer surface of the inner container for attachment of the pack to a surface. The attaching means may be an engagement means mounted on or integral to the inner container such as a hook shaped portion of the inner container. In embodiments in which the inner container is attached to a rigid backing member is provided with attachment means, for example the backing member may be shaped, for example as a hook to provide the attachment means.
The attachment means provides a means to locate the dispenser near to the patient for example by attachment to the bed or cot rail so that the medicament vapour diffuses slowly from the inner container. Thus the medicament vapour can be inhaled by the patient for example when asleep to provide a long lasting effect.
A further advantage of the pack of the present invention is that the rate of diffusion of the medicament vapour from the pack may be controlled by the nature of the absorbent substrate and permeability of the inner container.
The dispensers of the present invention may be manufactured by impregnating a solid substrate with the liquid medicament and sealing the impregnated substrate inside the inner container. The impregnated substrate may be placed between two sheets of a plastics material which is impermeable to the liquid medicament and the sheets sealed around their periphery to enclose the substrate inside the inner container. At least one of the sheets should be permeable to the vapour of the medicament. Alternatively the substrate may be placed inside a pouch of a vapour-permeable plastics material which is subsequently sealed at its open end to enclose the substrate. The substrate may be impregnated before it is placed inside the pouch or after the substrate has been inserted. In an alternative, the liquid medicament may be placed in the pouch prior to the insertion of the substrate. The impregnated substrate inside the inner container is then placed inside the outer container. The outer container may be formed from two sheets of plastics material which are sealed around their periphery or it may be a pouch sealed on three sides into which the inner container is placed prior to sealing the outer container.
In embodiments in which the outer container is formed by a film attached to a rigid backing member, the dispenser may be assembled by placing a substrate impregnated with the liquid medicament on the backing member, placing a film of vapour-permeable material over the substrate and sealing that film to the backing member around its periphery to form an inner container and then placing a film of vapour-impermeable material over the inner container and sealing it around its periphery to the backing member.
Before use the outer container prevents leakage of either vapour or liquid medicament. In use the outer container is opened, which allows the medicament vapour to diffuse slowly through the inner container, to be inhaled by the user. The medicament liquid remains within the inner container absorbed onto the substrate.
Specific embodiments of the invention will now be described with reference to the accompanying drawings in which:-
Figure 1 is a plan view of a first embodiment of the present invention, Figure 2 is a cross-sectional view of a second embodiment of the present invention, and
Figure 3 is a plan view of the second embodiment shown in Figure 2.
The dispenser shown in Figure 1 contains a single dose of a Karvol (RTM) liquid decongestant inhalation product. The impregnated substrate is located between two sheets 2,3 of a microperforated plastics material which are sealed together around their periphery, for example by heat sealing, to form an inner container enclosing the impregnated substrate. The inner container is then placed between two sheets 4,5 of material which are impermeable to the vapour of the medicament and which are sealed around their periphery to prevent any loss of medicament vapour until the seal is broken by the user. If the outer container is made of a plastics material such as a polyvinylchloride polymer coated on what will be the inner surface of the outer container with a further plastics material such as a polyvinylidene chloride polymer, the sealing may be performed by heat sealing or radio frequency welding. If the sheets have a coating or film of aluminium then the sealing must be performed by the use of an adhesive. To use the dispenser, the seal of the outer container is broken and the inner container is removed. This allows the volatile, aromatic Karvol (RTM) vapour to diffuse slowly from the inner container to be inhaled by the user.
In the embodiment shown in Figures 2 and 3, a substrate 11 impregnated with a volatile liquid medicament is located on a backing member 10 which is made of a material which is impervious to the liquid medicament and to the vapour of the medicament. Preferably the backing member 10 is made from a rigid plastics material. The impregnated substrate 11 is retained in position by a vapour permeable film 12 which is sealed around its periphery to the backing member 10 by a seal 13. A further film 14 of vapour impermeable material is sealed to the backing member 10 by a peripheral seal 15 which is located outside the seal 13.
The further film may be provided with areas of weakness
(not shown) which allow a central portion of the further film 14 to be removed to allow the medicament vapour to escape. Alternatively the seal 15 may be such that the further film 14 can be removed from the backing member
10. The backing member 10 is shaped in the form of a hook 16 to enable the dispenser to be hung near the patient for example on the rail of a child's cot.

Claims

1. A dispenser for administering a volatile liquid medicament comprising an inner container adapted to hold the liquid medicament, said inner container being permeable to vapour from the medicament, but substantially impermeable to the liquid medicament, and an outer container within which the first retaining means has been sealed, the outer container being impermeable to the medicament as liquid or vapour.
2. A dispenser as claimed in claim 1 in which an absorbent substrate for the liquid medicament is provided within the inner container.
3. A dispenser according to any preceding claim, in which the absorbent substrate is a fabric, a synthetic or natural sponge, a foamed plastics woven or non-woven material or paper.
4. A dispenser according to claim 3, in which the substrate is tissue paper.
5. A dispenser as claimed in any preceding claim in which the inner container comprises over all or part of its surface a microperforated plastics material.
6. A dispenser as claimed in claims 1 to 5 in which the inner container is formed from two sheets of vapour- permeable but liquid-impermeable material sealed together around their periphery to enclose the liquid medicament and the outer container is formed from two sheets of vapour-impermeable material sealed together around their periphery to enclose the inner container.
7. A dispenser as claimed in claim 6 in which the inner container is provided with attachment means.
8. A dispenser as claimed in any preceding claim in which the inner container is formed by sealing a film of vapour permeable material around its periphery to a rigid plastics backing member to enclose the liquid medicament and the outer container is formed by sealing a film of vapour impermeable material around its periphery to the backing member to enclose the inner container.
9. A dispenser as claimed in claim 8 in which the backing member is provided with attachment means.
10. A dispenser as claimed in any preceding claim wherein the liquid medicament is a liquid decongestant inhalation product comprising an aromatic mixture of pine oil, cinnamon oil and menthol.
PCT/EP1994/000513 1993-02-22 1994-02-18 Medicament presentation WO1994019043A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU62048/94A AU6204894A (en) 1993-02-22 1994-02-18 Medicament presentation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939303538A GB9303538D0 (en) 1993-02-22 1993-02-22 Medicament presentation
GB9303538.4 1993-02-22

Publications (1)

Publication Number Publication Date
WO1994019043A1 true WO1994019043A1 (en) 1994-09-01

Family

ID=10730840

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1994/000513 WO1994019043A1 (en) 1993-02-22 1994-02-18 Medicament presentation

Country Status (4)

Country Link
AU (1) AU6204894A (en)
GB (1) GB9303538D0 (en)
WO (1) WO1994019043A1 (en)
ZA (1) ZA941194B (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0701845A1 (en) * 1994-09-15 1996-03-20 Parker Medical Associates Custom body protective pad with cure-retarding storage system
EP0782431A1 (en) * 1994-09-02 1997-07-09 Barry James Murchie Baby's breathing aid
EP0792652A1 (en) * 1996-02-29 1997-09-03 S.C. Johnson & Son, Inc. Vapour release device
GB2359025A (en) * 2000-02-08 2001-08-15 Jennifer Albrighton Decongestant dispenser
WO2003006315A2 (en) * 2001-07-11 2003-01-23 Medical Express (Uk) Ltd Packaging for a fluid composition
WO2003103550A2 (en) * 2002-06-08 2003-12-18 Ian Robert Thomson Delivery system for a medicament or well-being enhancing composition
WO2007092634A2 (en) * 2006-02-09 2007-08-16 Christy Frank L Nasal comfort devices and methods
WO2009043592A2 (en) * 2007-10-03 2009-04-09 Gerard Hayes A multi - oil nasal and oral inhaler system
EP2145643A1 (en) 2008-07-19 2010-01-20 Markus Storz Portioned medicine
DE102011000223A1 (en) 2011-01-19 2012-07-19 Acuros GmbH, Berlin Device for releasing a volatile active substance, method for producing such a device and its use
EP3325063B1 (en) * 2015-07-20 2022-10-05 Medical Developments International Limited Inhaler device for inhalable liquids

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US2630802A (en) * 1950-09-20 1953-03-10 Tops Plastics Inc Inhaler and method of constructing it
EP0019010A1 (en) * 1979-05-10 1980-11-26 Sy Hyman Article for the dispersion of a volatile substance and an article of manufacture comprising a plurality of said articles
EP0131759A2 (en) * 1983-07-18 1985-01-23 Dr. Werner Freyberg, Chemische Fabrik, Delitia Nachf. Bags for insecticides
EP0290856A2 (en) * 1987-05-15 1988-11-17 FARMITALIA CARLO ERBA S.r.l. Signalling and repelling water soluble powder container

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2630802A (en) * 1950-09-20 1953-03-10 Tops Plastics Inc Inhaler and method of constructing it
EP0019010A1 (en) * 1979-05-10 1980-11-26 Sy Hyman Article for the dispersion of a volatile substance and an article of manufacture comprising a plurality of said articles
EP0131759A2 (en) * 1983-07-18 1985-01-23 Dr. Werner Freyberg, Chemische Fabrik, Delitia Nachf. Bags for insecticides
EP0290856A2 (en) * 1987-05-15 1988-11-17 FARMITALIA CARLO ERBA S.r.l. Signalling and repelling water soluble powder container

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0782431A1 (en) * 1994-09-02 1997-07-09 Barry James Murchie Baby's breathing aid
EP0782431A4 (en) * 1994-09-02 1998-11-18 Barry James Murchie Baby's breathing aid
EP0701845A1 (en) * 1994-09-15 1996-03-20 Parker Medical Associates Custom body protective pad with cure-retarding storage system
EP0792652A1 (en) * 1996-02-29 1997-09-03 S.C. Johnson & Son, Inc. Vapour release device
GB2359025A (en) * 2000-02-08 2001-08-15 Jennifer Albrighton Decongestant dispenser
WO2003006315A2 (en) * 2001-07-11 2003-01-23 Medical Express (Uk) Ltd Packaging for a fluid composition
WO2003006315A3 (en) * 2001-07-11 2003-05-08 Medical Express Uk Ltd Packaging for a fluid composition
US7784710B2 (en) 2002-06-08 2010-08-31 Ian Robert Thomson Delivery system for a medicament or well-being enhancing composition
WO2003103550A3 (en) * 2002-06-08 2004-02-26 Ian Robert Thomson Delivery system for a medicament or well-being enhancing composition
JP2005528955A (en) * 2002-06-08 2005-09-29 トムソン，イアン，ロバート Drug / health enhancer administration device
WO2003103550A2 (en) * 2002-06-08 2003-12-18 Ian Robert Thomson Delivery system for a medicament or well-being enhancing composition
WO2007092634A2 (en) * 2006-02-09 2007-08-16 Christy Frank L Nasal comfort devices and methods
WO2007092634A3 (en) * 2006-02-09 2008-01-17 Frank L Christy Nasal comfort devices and methods
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ZA941194B (en) 1994-09-21
AU6204894A (en) 1994-09-14
GB9303538D0 (en) 1993-04-07

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