WO1994024944A1 - Method, device and apparatus for reversible contraceptive sterilization - Google Patents

Method, device and apparatus for reversible contraceptive sterilization Download PDF

Info

Publication number
WO1994024944A1
WO1994024944A1 PCT/CZ1993/000013 CZ9300013W WO9424944A1 WO 1994024944 A1 WO1994024944 A1 WO 1994024944A1 CZ 9300013 W CZ9300013 W CZ 9300013W WO 9424944 A1 WO9424944 A1 WO 9424944A1
Authority
WO
WIPO (PCT)
Prior art keywords
blocking body
fallopian tube
flexible
sterilization
mandren
Prior art date
Application number
PCT/CZ1993/000013
Other languages
French (fr)
Inventor
Bohdan Babinec
Radim Uzel
Original Assignee
Bohdan Babinec
Radim Uzel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bohdan Babinec, Radim Uzel filed Critical Bohdan Babinec
Priority to AU38868/93A priority Critical patent/AU3886893A/en
Priority to PCT/CZ1993/000013 priority patent/WO1994024944A1/en
Publication of WO1994024944A1 publication Critical patent/WO1994024944A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/1219—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices expandable in contact with liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/20—Vas deferens occluders; Fallopian occluders
    • A61F6/22—Vas deferens occluders; Fallopian occluders implantable in tubes
    • A61F6/225—Vas deferens occluders; Fallopian occluders implantable in tubes transcervical

Definitions

  • the invention realates to a method, device and apparatus for reversible contraceptive sterilization.
  • the sterilization technique that has been applied up to this time and methods how it was applied constituted in reality an irreversible sterilization method.
  • This method consisted e.g. in a ligation of the fallopian tubes through the abdominal wall either by laparotomy or by laparoscopy. Apart from the necessity to perform this relatively serious surgical intervention in anesthesia, this method is dis ⁇ advantageous mainly for its irreversibility as the woman is not able to conceive and be a true mother for ever. The same consequence has also if the sterilization is carried out by the diathermocoagulation of the fallopian tubes using a laparoscope. Again it is a relatively complicated opera ⁇ tion in anesthesia which is expensive and potentially dange ⁇ rous for the woman.
  • barrier methods of contraception are known that use a pessary of various design. Their substantial disadvan ⁇ tage is that the pessary is necessary to be inserted before each intercourse what substantially limits the probability to apply this method. In addition to it, not every woman is able to learn how to insert a pessary reliably. A certain number of women also have allergy to the rubber material used to make a pessary. This allergy can also be observed in cases when the man uses a condom. This method of contra ⁇ ception is considered by the man as a complication and makes the woman dependant on man's behaviour in contraception.
  • the intra-utherine contraceptive devices inserted into the uterine cavity by physicians are known to be used. But this method is not a reliable contraception in all cases as it is not one hundred percent effective. In addition to it, this method brings about dangerous side-effects, especially inflamations and bleedings.
  • the method according to the invention consists in inserting a device according to the invention into each fallopian tube using preferably the apparatus according to the invention.
  • the device closes the fallopian tube and is left there for the desired selected sterilization time.
  • the device consists of a blocking body provided with a mani ⁇ pulation thread.
  • the device in the application of the method according to the invention it is preferable to insert the device by means of the apparatus for reversible contraceptive sterilization according to the invention.
  • This apparatus consists of a flexible catheter with a flexible mandren inserted into it.
  • the above mentioned device is inserted into the flexible catheter in front of the flexible mandren and is inserted by the apparatus into one fallopian tube and deposited there. The method is then repeated for the other fallopian tube using another piece of the device.
  • the method of the reversible contraceptive sterilization according to the invention makes possible to sterilize by a simple operation.
  • the sterility lasts for the desired time that can be even very long, in reality unlimited, but it is terminable at any time.
  • the device for the reversible contraceptive sterilization is inert when introduced into an organism, causes no side-effects and if applied in both fallopian tubes the sterilization is reliable to one hundred percent.
  • the apparatus for the reversible contraceptive sterilization according to the invention per itts a simple, quick and undemanding sterilization.
  • the invention is further illustrated by means of the accom ⁇ panied drawings where the Figure 1 shows the method accor ⁇ ding to the invention in its first phase, the Figure 2 shows the next phase, the Figure 3 shows the device inserted by the method according to the invention, the Figure 4 shows section through the apparatus used to carry out the method according to the invention and the Figure 5 shows a detailed enlarged section through the device used in the application of the method according to the invention.
  • the method according to the invention is carried out accor ⁇ ding to the Figures 1, 2 and 3 using the apparatus according to the Figure 4 and the device according to the Figure 5.
  • a flexible catheter 1 is used with a flexible mandren 3_ run ⁇ ning through its axial opening 2.
  • the maximal external dia ⁇ meter of the flexible catheter 1 has to correspond to its possibility to be inserted into the orifice of the fallopian tube.
  • the internal diameter of the flexible catheter 1 has to be such as to make possible to deposit the blocking body 4. in it ( Figure 4, 5) at least at its end.
  • the blocking body 4. has preferrably the shape of a short rod or cylinder with rounded tips.
  • the manipulation thread J> is fastened in the blocking body 4. and led out of it.
  • the mani ⁇ pulation thread !5 which is preferrably made from Mersilk, is fastened in the blocking body 4. for example so that it is provided with knots ⁇ _ by which it is fastened in the blocking body 4. during its moulding, e.g. by casting or injection moulding into a mould with the inserted thread £5.
  • the manipulation thread 5. can be fixed also by other methods, e.g. so that its cross-section is increased during the blocking body 4. production.
  • the blocking body 4. is preferably made from hydrophile swellable gel, but another material can also be used if it is indifferent to the organism.
  • the method according to the invention is carried out so that using a not shown hysteroscope inserted into the utherine cavity 1_ the flexible cathetre 1 with the blocking body 4. deposited in its axial cavity 2 at the end of the flexible mandren 3_ is inserted into the orifice of the fallopian tube 8_.
  • this flexible cathetre 1 has been inserted through the vagina 9_ and the utherine cavity 1_ into the fallopian tube 8. orifice (Fig. 1) you start to pull the flexible catheter 1 out and at the same time you hold the blocking body 4. by the flexible mandren 3_ in its place, resp. you push it by the mandren 3_ with some feeling into the fallo ⁇ pian tube 8. so that you do not feel any resistance.
  • the blocking body 4. has to remain in the place to which it was transported.
  • the flexible catheter 1 is removed from the utherine cavity 1_ an( * subsequently also the flexible mandren 3_, respectively the removal of the flexible catheter 1 and the flexible mandren 3_ is carried out subse ⁇ quently after the flexible catheter 1 has been pulled out of the fallopian tube 8. and the blocking body 4. in simultane ⁇ ously held in its place. Thereafter, the flexible mandren 2 can be pulled out together with the partially pulled out flexible catheter 1.
  • the blocking body 4. from a hydrophilic swelling gel swells so that it completely closes the passage to the fallopian tube 8. as it comes into contact with the fallopian tube 8_ wall.
  • the blocking body 4. remains in the fallopian tube 8_ for the desired time and reliably prevents the passage of spermatozoons to an ovum as it closes the passage through the fallopian tube 8_.
  • Correct introduction of the blocking body 4. can be checked by X-raying or by sonografy if the blocking body 4 contains an admixture of a detectable compound, e.g. of baryum sulphate.
  • a detectable compound e.g. of baryum sulphate.
  • the blocking body 4 is pulled out by pulling on the manipulation thread £5. The same is carried out also in the other fallopian tube 8. and the other blocking body 4. is also pulled out.

Abstract

A method of the reversible contraceptive sterilization where a blocking device is inserted into the fallopian tubes, that closes the passage through the fallopian tube and is left there for the desired sterilization time, and an apparatus to carry out this method where a blocking body (4) is placed in a flexible catheter (1) in front of the flexible mandren (3) inserted in the flexible catheter (1) and a device to carry out the method according to invention, formed by the blocking body (4) provided with the manipulation thread (5).

Description

Method, Device and Apparatus for Reversible Contraceptive Sterilization
Field of the Art
The invention realates to a method, device and apparatus for reversible contraceptive sterilization.
Prior Art
The sterilization technique that has been applied up to this time and methods how it was applied constituted in reality an irreversible sterilization method. This method consisted e.g. in a ligation of the fallopian tubes through the abdominal wall either by laparotomy or by laparoscopy. Apart from the necessity to perform this relatively serious surgical intervention in anesthesia, this method is dis¬ advantageous mainly for its irreversibility as the woman is not able to conceive and be a true mother for ever. The same consequence has also if the sterilization is carried out by the diathermocoagulation of the fallopian tubes using a laparoscope. Again it is a relatively complicated opera¬ tion in anesthesia which is expensive and potentially dange¬ rous for the woman.
Also, some barrier methods of contraception are known that use a pessary of various design. Their substantial disadvan¬ tage is that the pessary is necessary to be inserted before each intercourse what substantially limits the posibility to apply this method. In addition to it, not every woman is able to learn how to insert a pessary reliably. A certain number of women also have allergy to the rubber material used to make a pessary. This allergy can also be observed in cases when the man uses a condom. This method of contra¬ ception is considered by the man as a complication and makes the woman dependant on man's behaviour in contraception.
Also, the intra-utherine contraceptive devices inserted into the uterine cavity by physicians are known to be used. But this method is not a reliable contraception in all cases as it is not one hundred percent effective. In addition to it, this method brings about dangerous side-effects, especially inflamations and bleedings.
Application of the hormonal drugs for the purpose of contraception requires a regular administration to guarantee the necessary effectiveness. In a number of cases it is necessary to take into accout certain unwanted side effects and consequences that can often manifest only after a long time and that can effect detrimentally on woman health.
Therefore, it can be concluded that the existing methods and means to carry out contraception or sterilization are always in some way disadvantageous. Either the irreversible steri¬ lization is caused that prevents conception for ever, and can be a difficult and serious operation at the same time as it causes permanent blocking of the fallopian tubes, or the applied contraception method brings about a possibility of complications and side-effects. Also, many contraceptive methods are not one hundred percent effective. Summary of the Invention
The above mentioned drawbacks of the already known methods are nearly completely eliminated if the method, device and apparatus for reversible contraceptive sterilization according to the invention are used.
The method according to the invention consists in inserting a device according to the invention into each fallopian tube using preferably the apparatus according to the invention. The device closes the fallopian tube and is left there for the desired selected sterilization time.
The device consists of a blocking body provided with a mani¬ pulation thread.
In the application of the method according to the invention it is preferable to insert the device by means of the apparatus for reversible contraceptive sterilization according to the invention. This apparatus consists of a flexible catheter with a flexible mandren inserted into it. The above mentioned device is inserted into the flexible catheter in front of the flexible mandren and is inserted by the apparatus into one fallopian tube and deposited there. The method is then repeated for the other fallopian tube using another piece of the device.
The method of the reversible contraceptive sterilization according to the invention makes possible to sterilize by a simple operation. The sterility lasts for the desired time that can be even very long, in reality unlimited, but it is terminable at any time. The device for the reversible contraceptive sterilization is inert when introduced into an organism, causes no side-effects and if applied in both fallopian tubes the sterilization is reliable to one hundred percent.
The apparatus for the reversible contraceptive sterilization according to the invention per itts a simple, quick and undemanding sterilization.
Brief Description of the Drawings
The invention is further illustrated by means of the accom¬ panied drawings where the Figure 1 shows the method accor¬ ding to the invention in its first phase, the Figure 2 shows the next phase, the Figure 3 shows the device inserted by the method according to the invention, the Figure 4 shows section through the apparatus used to carry out the method according to the invention and the Figure 5 shows a detailed enlarged section through the device used in the application of the method according to the invention.
Preferred Embodiment of the Invention
The method according to the invention is carried out accor¬ ding to the Figures 1, 2 and 3 using the apparatus according to the Figure 4 and the device according to the Figure 5.
A flexible catheter 1 is used with a flexible mandren 3_ run¬ ning through its axial opening 2. The maximal external dia¬ meter of the flexible catheter 1 has to correspond to its possibility to be inserted into the orifice of the fallopian tube. The internal diameter of the flexible catheter 1 has to be such as to make possible to deposit the blocking body 4. in it (Figure 4, 5) at least at its end.
The blocking body 4. has preferrably the shape of a short rod or cylinder with rounded tips. The manipulation thread J> is fastened in the blocking body 4. and led out of it. The mani¬ pulation thread !5, which is preferrably made from Mersilk, is fastened in the blocking body 4. for example so that it is provided with knots §_ by which it is fastened in the blocking body 4. during its moulding, e.g. by casting or injection moulding into a mould with the inserted thread £5. The manipulation thread 5. can be fixed also by other methods, e.g. so that its cross-section is increased during the blocking body 4. production. The blocking body 4. is preferably made from hydrophile swellable gel, but another material can also be used if it is indifferent to the organism.
The method according to the invention is carried out so that using a not shown hysteroscope inserted into the utherine cavity 1_ the flexible cathetre 1 with the blocking body 4. deposited in its axial cavity 2 at the end of the flexible mandren 3_ is inserted into the orifice of the fallopian tube 8_. When this flexible cathetre 1, has been inserted through the vagina 9_ and the utherine cavity 1_ into the fallopian tube 8. orifice (Fig. 1) you start to pull the flexible catheter 1 out and at the same time you hold the blocking body 4. by the flexible mandren 3_ in its place, resp. you push it by the mandren 3_ with some feeling into the fallo¬ pian tube 8. so that you do not feel any resistance. The blocking body 4. has to remain in the place to which it was transported.
Thereafter, the flexible catheter 1 is removed from the utherine cavity 1_ an(* subsequently also the flexible mandren 3_, respectively the removal of the flexible catheter 1 and the flexible mandren 3_ is carried out subse¬ quently after the flexible catheter 1 has been pulled out of the fallopian tube 8. and the blocking body 4. in simultane¬ ously held in its place. Thereafter, the flexible mandren 2 can be pulled out together with the partially pulled out flexible catheter 1. Within a relatively short time, about one day, the blocking body 4. from a hydrophilic swelling gel swells so that it completely closes the passage to the fallopian tube 8. as it comes into contact with the fallopian tube 8_ wall.
The same method is applied also to the other fallopian tube 8_ if it is functional. Thereafter, the manipulation thread 5 is shortened to the necessary length.
The blocking body 4. remains in the fallopian tube 8_ for the desired time and reliably prevents the passage of spermatozoons to an ovum as it closes the passage through the fallopian tube 8_.
Correct introduction of the blocking body 4. can be checked by X-raying or by sonografy if the blocking body 4 contains an admixture of a detectable compound, e.g. of baryum sulphate.
If it is decided to terminate the sterilization to restore fertility the blocking body 4 is pulled out by pulling on the manipulation thread £5. The same is carried out also in the other fallopian tube 8. and the other blocking body 4. is also pulled out.
The commercial use of this invention will be constituted by any production of the apparatus and/or the device for the purpose to use them in carrying out the invented method.

Claims

C l a i m s
1. A method of the reversible contraceptive sterilization characterized in that the blocking body that closes the passage through the fallopian tube is inserted there and left there for the decided sterilization time.
2. The method according to claim 1, characterized in that the inserted blocking body is removed from the fallopian tube to restore fertility.
3. The method according to claim 1, characterized in that the blocking body dilates spontaneously after insertion into the fallopian tube and closes the passage through the fallopian tube.
4. The method according to claim 1, characterized in that after insertion of the blocking body made with admixture of a sonographically or by X-rays detectable compound into the fallopian tube the insertion is checked by X-rays or sonographically.
5. The method according to claim 1, characterized in that the blocking body from hydrophilic swelling gel is inserted into the fallopian tube.
6. The method according to claim 1, characterized in that after insertion of a hysteroscope the flexible cathetre with the blocking body is inserted into the orifice of the fallopian tube, the blocking body is pushed and/or hold in the fallopian tube by the flexible mandren and when the flexible catheter and flexible mandren are pulled out the blocking body is left in the fallopian tube and by swelling closes the passage through it.
7. An apparatus for reversible contraceptive sterilization to be used in carrying out the method according to claim 1, characterized in that the blocking body (4) is deposited in the flexible catheter (1) in front of the flexible mandren (3) introduced into the flexible catheter (1) .
8. The apparatus according to claim 7, characterized in that the blocking body (4) is deposited in the end of the axial opening (2) of the flexible catheter (1) .
9. A device for the reversible contraceptive steriliza¬ tion determined to carry out the method according to claim 1, characterized in that it is formed by the blocking body (4) provided with the manipulation thread (5) .
10. The device according to claim 9, characterized in that the manipulation thread (5) is fixed in the blocking body (4) and led out of it.
11. The device according to claim 10, characterized in that the manipulation thread (5) is fixed in the blocking body (4) by knots (6) made on it.
12. The device according to claim 10, characterized in that the manipulation thread (5) is fixed in the blocking body (4) by its increased cross-section.
13. The device according to claim 9, characterized in that the blocking body (4) is made as a rod from hydrophile swellable -gel.
14. The device according to claim 9, characterized in that the blocking body (4) is made as a cylinder from hydrofile swellable gel.
15. The device according to claim 9, characterized in that the blocking body (4) is provided with a sonographical¬ ly or by X-rays detectable compound.
PCT/CZ1993/000013 1993-04-23 1993-04-23 Method, device and apparatus for reversible contraceptive sterilization WO1994024944A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU38868/93A AU3886893A (en) 1993-04-23 1993-04-23 Method, device and apparatus for reversible contraceptive sterilization
PCT/CZ1993/000013 WO1994024944A1 (en) 1993-04-23 1993-04-23 Method, device and apparatus for reversible contraceptive sterilization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CZ1993/000013 WO1994024944A1 (en) 1993-04-23 1993-04-23 Method, device and apparatus for reversible contraceptive sterilization

Publications (1)

Publication Number Publication Date
WO1994024944A1 true WO1994024944A1 (en) 1994-11-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CZ1993/000013 WO1994024944A1 (en) 1993-04-23 1993-04-23 Method, device and apparatus for reversible contraceptive sterilization

Country Status (2)

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WO (1) WO1994024944A1 (en)

Cited By (15)

* Cited by examiner, † Cited by third party
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WO1998026737A1 (en) * 1996-12-18 1998-06-25 Ovion, Inc. Contraceptive system and method of use
US6096052A (en) * 1998-07-08 2000-08-01 Ovion, Inc. Occluding device and method of use
US6679266B2 (en) 1995-06-07 2004-01-20 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
JP2007521081A (en) * 2003-06-27 2007-08-02 エイエムエス・リサーチ・コーポレーション Method and apparatus for occlusion of body lumens and / or delivery of therapeutic agents
US7686020B2 (en) 1995-06-07 2010-03-30 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US7934504B2 (en) 1999-08-23 2011-05-03 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US8562628B2 (en) 2006-04-03 2013-10-22 Conceptus, Inc. Linear motion delivery system for female sterilization device
US9034053B2 (en) 2004-02-25 2015-05-19 Femasys Inc. Methods and devices for conduit occlusion
US9220880B2 (en) 2004-02-25 2015-12-29 Femasys Inc. Methods and devices for delivery of compositions to conduits
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US9402762B2 (en) 2004-02-25 2016-08-02 Femasys Inc. Methods and devices for conduit occlusion
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
US9713549B2 (en) 2004-02-02 2017-07-25 Bayer Healthcare Llc Contraceptive with permeable and impermeable components
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
CN109907870A (en) * 2019-03-22 2019-06-21 佘彩芹 The hollow contraceptive device of Pear-Shaped

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US8733361B2 (en) 1995-06-07 2014-05-27 Bayer Essure Inc. Occlusion devices and methods
US8356599B2 (en) 1995-06-07 2013-01-22 Conceptus, Inc. Occlusion devices and methods
US8327852B2 (en) 1995-06-07 2012-12-11 Conceptus, Inc. Occlusion devices and methods
US8171936B2 (en) 1995-06-07 2012-05-08 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
US6679266B2 (en) 1995-06-07 2004-01-20 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
US8066007B2 (en) 1995-06-07 2011-11-29 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and their delivery
US7686020B2 (en) 1995-06-07 2010-03-30 Conceptus, Inc. Contraceptive transcervical fallopian tube occlusion devices and methods
EP1438939A3 (en) * 1996-12-18 2004-08-04 Ovion, Inc. Contraceptive system
US7073504B2 (en) 1996-12-18 2006-07-11 Ams Research Corporation Contraceptive system and method of use
AU726548B2 (en) * 1996-12-18 2000-11-09 Bayer Essure, Inc. Contraceptive system and method of use
US6432116B1 (en) 1996-12-18 2002-08-13 Ovion, Inc. Occluding device and method of use
EP1438938A3 (en) * 1996-12-18 2004-08-04 Ovion, Inc. Contraceptive system
US7398780B2 (en) 1996-12-18 2008-07-15 Ams Research Corporation Contraceptive system and method of use
JP2008080141A (en) * 1996-12-18 2008-04-10 Ams Research Corp Contraceptive system
WO1998026737A1 (en) * 1996-12-18 1998-06-25 Ovion, Inc. Contraceptive system and method of use
US8733360B2 (en) 1997-09-24 2014-05-27 Bayer Essure Inc. Occlusion devices and methods
US8613282B2 (en) 1997-09-24 2013-12-24 Conceptus, Inc. Occlusion devices and methods
US6096052A (en) * 1998-07-08 2000-08-01 Ovion, Inc. Occluding device and method of use
US8584679B2 (en) 1999-08-23 2013-11-19 Conceptus, Inc. Deployment actuation system
US9597224B2 (en) 1999-08-23 2017-03-21 Bayer Healthcare Llc Deployment actuation system
US8381733B2 (en) 1999-08-23 2013-02-26 Conceptus, Inc. Deployment actuation system
US8079364B2 (en) 1999-08-23 2011-12-20 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
US8695604B2 (en) 1999-08-23 2014-04-15 Bayer Essure Inc. Deployment actuation system
US7934504B2 (en) 1999-08-23 2011-05-03 Conceptus, Inc. Deployment actuation system for intrafallopian contraception
JP2007521081A (en) * 2003-06-27 2007-08-02 エイエムエス・リサーチ・コーポレーション Method and apparatus for occlusion of body lumens and / or delivery of therapeutic agents
US9713549B2 (en) 2004-02-02 2017-07-25 Bayer Healthcare Llc Contraceptive with permeable and impermeable components
US9034053B2 (en) 2004-02-25 2015-05-19 Femasys Inc. Methods and devices for conduit occlusion
US10111687B2 (en) 2004-02-25 2018-10-30 Femasys, Inc. Methods and devices for conduit occlusion
US9308023B2 (en) 2004-02-25 2016-04-12 Femasys Inc. Methods and devices for conduit occlusion
US9402762B2 (en) 2004-02-25 2016-08-02 Femasys Inc. Methods and devices for conduit occlusion
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