WO1995003084A3 - Extracorporeal affinity adsorption devices - Google Patents

Extracorporeal affinity adsorption devices Download PDF

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Publication number
WO1995003084A3
WO1995003084A3 PCT/US1994/008043 US9408043W WO9503084A3 WO 1995003084 A3 WO1995003084 A3 WO 1995003084A3 US 9408043 W US9408043 W US 9408043W WO 9503084 A3 WO9503084 A3 WO 9503084A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracorporeal
diseases
affinity adsorption
adsorption devices
immunotherapy
Prior art date
Application number
PCT/US1994/008043
Other languages
French (fr)
Other versions
WO1995003084A2 (en
Inventor
Meir Strahilevitz
Original Assignee
Meir Strahilevitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meir Strahilevitz filed Critical Meir Strahilevitz
Priority to EP94924465A priority Critical patent/EP0710135B1/en
Priority to AU74725/94A priority patent/AU7472594A/en
Priority to DE69435170T priority patent/DE69435170D1/en
Priority to US08/464,898 priority patent/US6039946A/en
Publication of WO1995003084A2 publication Critical patent/WO1995003084A2/en
Publication of WO1995003084A3 publication Critical patent/WO1995003084A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Abstract

Extracorporeal affinity adsorption devices which are aimed at the substantial removal of two or more compounds that are etiological in the pathogenesis of diseases in man, provide effective therapeutic intervention means for these diseases. The devices are particularly suitable for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases. Extracorporeal chelation and immunotherapy for artherosclerosis, extracorporeal chelation treatment with on-line regeneration or replacement of chelant, extracorporeal immunotherapy with antibody fragments, and extracorporeal immunoadsorption utilizing antibodies bound to Protein A are also disclosed.
PCT/US1994/008043 1993-07-23 1994-07-20 Extracorporeal affinity adsorption devices WO1995003084A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP94924465A EP0710135B1 (en) 1993-07-23 1994-07-20 Extracorporeal Affinity Adsorption Devices
AU74725/94A AU7472594A (en) 1993-07-23 1994-07-20 Extracorporeal affinity adsorption devices
DE69435170T DE69435170D1 (en) 1993-07-23 1994-07-20 Extrakorporeal devices for adsorption by affinity
US08/464,898 US6039946A (en) 1993-07-23 1994-07-20 Extracorporeal affinity adsorption devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/097,378 1993-07-23
US08/097,378 US5753227A (en) 1993-07-23 1993-07-23 Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases

Publications (2)

Publication Number Publication Date
WO1995003084A2 WO1995003084A2 (en) 1995-02-02
WO1995003084A3 true WO1995003084A3 (en) 1995-03-16

Family

ID=22263054

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/008043 WO1995003084A2 (en) 1993-07-23 1994-07-20 Extracorporeal affinity adsorption devices

Country Status (6)

Country Link
US (6) US5753227A (en)
EP (1) EP0710135B1 (en)
AU (1) AU7472594A (en)
DE (1) DE69435170D1 (en)
IL (1) IL110382A (en)
WO (1) WO1995003084A2 (en)

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EP0710135A1 (en) 1996-05-08
US6569112B2 (en) 2003-05-27
US20020019603A1 (en) 2002-02-14
IL110382A0 (en) 1994-12-29
WO1995003084A2 (en) 1995-02-02
US6039946A (en) 2000-03-21
AU7472594A (en) 1995-02-20
EP0710135A4 (en) 1997-05-21
EP0710135B1 (en) 2008-11-26
US6264623B1 (en) 2001-07-24
US20040220508A1 (en) 2004-11-04
US6676622B2 (en) 2004-01-13
US20010039392A1 (en) 2001-11-08
DE69435170D1 (en) 2009-01-08
IL110382A (en) 1998-12-06

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