WO1995031226A1 - Thin wall catheter having enhanced torqueability characteristics - Google Patents
Thin wall catheter having enhanced torqueability characteristics Download PDFInfo
- Publication number
- WO1995031226A1 WO1995031226A1 PCT/IB1995/000120 IB9500120W WO9531226A1 WO 1995031226 A1 WO1995031226 A1 WO 1995031226A1 IB 9500120 W IB9500120 W IB 9500120W WO 9531226 A1 WO9531226 A1 WO 9531226A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- intravascular catheter
- tubular body
- weight
- catheter
- peba
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/049—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0098—Catheters; Hollow probes having a strain relief at the proximal end, e.g. sleeve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/0069—Tip not integral with tube
Definitions
- the present invention relates to intravascular catheters, and more particularly to a diagnostic catheter having a relatively small outside diameter for its relatively large diameter internal lumen and which possesses excellent pushability and torqueability characteristics.
- angiography procedures are used to view the patency of selected blood vessels.
- a diagnostic catheter having a desired distal end curvature configuration is introduced into the femoral artery using the
- the catheter must have sufficient strength in the longitudinal direction so as not to kink or fold as it is advanced through the vascular system. It must also possess a lubricous core lumen to facilitate passage of a guidewire or possibly another catheter therethrough.
- a diagnostic catheter possess a relatively large lumen to allow fluids, such as radiopaque contrast fluid to be injected therethrough and out the distal end so that the area of the vascular system under investigation can be viewed fluoroscopically.
- the Jang et al. U.S. Patent 4,898,591 describes a diagnostic catheter having a tubular body formed from inner and outer tubular layers, there being a strengthening braid interposed between the inner and outer layers.
- Each of the inner and outer layers is formed from a blend of a nylon and an ester-linked polyether-polyamide copolymer.
- the present invention is deemed to be an advance over the prior art as represented by the Jang et al. patent in that it provides a diagnostic catheter having a minimal O.D. and a maximal I.D. while still maintaining the necessary torqueability and pushability characteristics.
- a diagnostic catheter having, for example, a 4 Fr O.D. but with an internal lumen that is as large as the internal lumen of a 5 Fr catheter that is currently commercially available.
- a 6 Fr catheter made in accordance with the present invention possesses an internal lumen that is about equal to that of a commercially-available 7 Fr catheter.
- a diagnostic intravascular catheter having an elongated tubular body with a proximal end, a distal end and a lumen extending therebetween where the tubular body is formed with an inner layer consisting essentially of an unmodified polyamide polymer, preferably Nylon-12.
- unmodified polyamide polymer refers to the fact that nothing is added to the polymer matrix that tends to substantially change its physical properties, such as copolymers, polymer blends, miscible polymers in relation to polyamide-based polymer matrices or polymer performance enhancers which would substantially change the physical properties of the polymer.
- Nylon- 12 is hydrophobic meaning that it does not absorb moisture and swell.
- a reinforcing sleeve Surrounding this inner layer is a reinforcing sleeve that extends from the proximal end of the tubular body toward the distal end.
- the sleeve may comprise braided filaments and may constrict the inner layer, creating microscopic bumps on the wall surface defining the lumen, effectively decreasing the contact area between an inserted guidewire and the wall surface.
- An outer layer including a blend of a polyether block amide having a predetermined diameter hardness in the range of from about 50 Shore D to 75 Shore D and preferably a radiopaque filler material (BaS0 4 ) , covers the inner layer and the reinforcing sleeve and provides an outer diameter to the tubular body in the range of from 3-8 Fr.
- a radiopaque filler material BaS0 4
- affixed to the distal end of the tubular body member is a soft-tip member, which may be molded from a blend of resins such that the soft tip exhibits a hardness that is less than about 45 Shore D.
- the intravascular catheter may also incorporate a non-braided tubular stem member that is interposed between and bonded to both the tubular body and the soft-tip member.
- the stem member itself preferably comprises a single layer of a copolymer of polyamide and PEBA whose Shore hardness is in the range of from 25D to 72D. It may have a uniform or tapered outer diameter.
- the catheter of the present invention generally incorporates a ring or band formed from a suitable metal or from a high temperature resistant plastic, such as polyimide sold under the trademark, KAPTON. This thin ring captures the ends of the wires comprising the braid, preventing them from fraying or otherwise distorting as a thermal bonding of a soft-tip or a tubular stem member takes place.
- Figure 1 is a perspective view of a diagnostic catheter constructed in accordance with the present invention
- Figure 2 is a cross-sectional view of the catheter of Figure 1 taken along the line 2-2;
- Figure 3 is a cross-sectional view taken through the stem member of the catheter along the line 3-3 in Figure 1,*
- Figure 4 is a longitudinal cross-sectional view taken along the line 4-4 which passes through the joint between the tubular body stock and the stem member,* and
- Figure 5 is a longitudinal cross-sectional view taken through the distal end portion of the catheter along the line 5-5 in Figure 1. Description of the Preferred Embodiment
- a diagnostic catheter comprising the present invention. It includes an elongated tubular body 12 having a proximal end 14, a distal end 16 and a lumen 18 extending therebetween.
- a molded plastic hub 20 having a Luer fitting 22 at its proximal end and flared wings 24 projecting radially from the diametrically opposed sides thereof to facilitate twisting of the catheter.
- An elastomeric sleeve 26 surrounds the proximal end portion of the tubular body 12 and functions as a strain relief member.
- the sleeve 26 is preferably roughened or knurled to facilitate gripping and rotation thereof using a three-finger catheter engagement.
- the length of the tubular body 12 will typically be 3-1/2 to 4 feet in length and will have an outside diameter that is generally uniform over this length and will come in various sizes from, say, 3 Fr to 8 Fr.
- the tubular body 12 is formed with an inner layer 28 which is preferably an unmodified polyamide, such as Nylon-12 ® .
- an inner layer 28 which is preferably an unmodified polyamide, such as Nylon-12 ® .
- Nylon-12 is found not to absorb ⁇ moisture and, hence, will not change in dimension when immersed in saline, body fluids and/or contrast media liquid.
- the inner layer 12 preferably has a wall thickness in the range of from 0.001 to 0.008 inch with 0.0025 ⁇ 0.0005 inch being preferred.
- a braided sleeve of metal wires 30 is formed about the inner layer 28. More particularly, the inner layer 28 will typically be extruded over a polyacetal mandrel, and following extrusion, is braided using stainless steel braid wire. Any one of a number of braid patterns may be used including, without limitation, staggered 2-over- 2-under or staggered 1-over-1-under.
- the braid angle may be adjusted to range anywhere from 20° to 60° from the perpendicular plane of the catheter.
- the braid wire diameter may fall in the range of from 0.0010 to 0.0030 inches.
- an outer layer 32 is extruded onto the assembly.
- the outer layer may comprise polyether block amide (PEBA) of a predetermined durometer hardness in the range from about 50 Shore D to 75 Shore D and preferably contains a radiopaque filler, such as barium sulfate BaS0 4 .
- PEBA polyether block amide
- the outer layer 32 totally embeds the braided sleeve and the die used with the extruder will provide a predetermined wall thickness yielding an outer diameter to the tubular body that is selected to be anywhere in the range of from 3 Fr to 8 Fr.
- the outer layer may comprise a blend of polyether block amides that exhibit differing durometers to yield a catheter body having a desired stiffness characteristic or "feel".
- the outer layer 32 may also be a blend of polyamide and PEBA.
- the outer layer may be a blend including, say, 63.8% by weight of a 72D PEBA having 36% BaS0 4 added as a radiopaque filler and 0.2% by weight of a pigment to provide a desired color to the tubular body.
- the outer layer may comprise a blend of 19.3% by weight polyamide, 44.5% of 70D PEBA and 36% by weight of BaS0 4 again with 0.2% by weight of a pigment added for color.
- a tubular stem member 34 is thermally bonded to the distal end portion of the braided tubular body 12.
- the braided tubular body has its outer layer or jacket 32 ground to a bevel as at 36.
- beveling the distal end portion 16 of the tubular body 12 greater surface area is provided for effecting attachment of the stem member 34.
- the grinding operation used to create the bevel reduces the thickness of the outer jacket relative to the ends of the wires 30 comprising the braided sleeve, it has been found expedient to provide a band or ring 38 of a non-penetrable material surrounding the free ends of the braid wires.
- the heating required to effect a thermal bond between the tubular body 12 and the jacket 34 can cause the frayed ends of the braid to warp or bend to the point where they can penetrate through the inner layer 28 into the lumen 18 or through the thickness of the tubular stem 34.
- the band 38 confines those ends during heating, preventing such undesired wall penetration.
- the band of non-penetrable material may comprise a metal, such as tantalum, titanium, iridium, gold, silver, stainless steel and alloys of such materials.
- a suitable high temperature polymers such as polyimide, e.g., KAPTON, can be used to constrain the free ends of the braid wires from penetrating the interior or exterior wall of the catheter during thermal bonding re-flow procedures.
- the stem member 34 may comprise a blend of PEBA ranging from, say, 25D to 72D with a polyamide, such as Nylon-12, along with a radiopaque filler, e.g., barium sulfate, being added, along with a desired pigment.
- PEBA polyamide
- a radiopaque filler e.g., barium sulfate
- a soft-tip member 40 which may be bonded to the distal end portion of the stem member 34.
- a suitable low durometer (25D - 40D) PEBA can be used.
- a PEBA blend with 15% to 45% by weight of radiopaque filler, such as BaS0 4/ may be used.
- a resin blend consisting of 48.6% 25D PEBA, 32.4% 40D PEBA, 15% BaS0 4 and 4% Ti0 2 pigment has been found to provide a soft, atraumatic tip. That tip may be formed by injection molding the material onto the distal end of the stem member 34.
- the soft-tip 40 may be injection molded directly onto a distal end portion of the braided tubular body 12 with a impenetrable ring 38 again being used to confine the braiding wire ends as the soft tip is being formed.
- An 8 Fr diagnostic catheter constructed in accordance with the present invention may have a lumen as large as 0.076 inches, again having the desirable properties expected by most cardiologists as far as its ability to be manipulated through the application of longitudinal and rotational forces at the proximal end portion of the catheter.
- intravascular catheter in accordance with the present invention can be manufactured to have a variety of different distal end shaped configurations to suit the desires of different cardiologists.
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MXPA/A/1996/005630A MXPA96005630A (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter that has improved the characteristics of tors |
CA002189135A CA2189135C (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter having enhanced torqueability characteristics |
AU16706/95A AU688858B2 (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter having enhanced torqueability characteristics |
EP95908358A EP0759788B1 (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter having enhanced torqueability characteristics |
AT95908358T ATE308351T1 (en) | 1994-05-18 | 1995-02-27 | THIN WALLED CATHETER WITH IMPROVED TORSION CHARACTERISTICS |
DE69534565T DE69534565T2 (en) | 1994-05-18 | 1995-02-27 | Thin-walled catheter with improved torsional properties |
JP7529480A JP2950995B2 (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter with enhanced torque characteristics |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/245,428 | 1994-05-18 | ||
US08/245,428 US5403292A (en) | 1994-05-18 | 1994-05-18 | Thin wall catheter having enhanced torqueability characteristics |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995031226A1 true WO1995031226A1 (en) | 1995-11-23 |
Family
ID=22926612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB1995/000120 WO1995031226A1 (en) | 1994-05-18 | 1995-02-27 | Thin wall catheter having enhanced torqueability characteristics |
Country Status (8)
Country | Link |
---|---|
US (3) | US5403292A (en) |
EP (1) | EP0759788B1 (en) |
JP (1) | JP2950995B2 (en) |
AT (1) | ATE308351T1 (en) |
AU (1) | AU688858B2 (en) |
CA (1) | CA2189135C (en) |
DE (1) | DE69534565T2 (en) |
WO (1) | WO1995031226A1 (en) |
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Also Published As
Publication number | Publication date |
---|---|
DE69534565D1 (en) | 2005-12-08 |
DE69534565T2 (en) | 2006-06-14 |
EP0759788A1 (en) | 1997-03-05 |
MX9605630A (en) | 1998-05-31 |
CA2189135C (en) | 2001-06-12 |
ATE308351T1 (en) | 2005-11-15 |
EP0759788B1 (en) | 2005-11-02 |
CA2189135A1 (en) | 1995-11-23 |
JPH09506026A (en) | 1997-06-17 |
AU1670695A (en) | 1995-12-05 |
AU688858B2 (en) | 1998-03-19 |
JP2950995B2 (en) | 1999-09-20 |
US5725513A (en) | 1998-03-10 |
US5599325A (en) | 1997-02-04 |
US5403292A (en) | 1995-04-04 |
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