WO1996008229A3 - Matrix for transdermal drug delivery - Google Patents

Matrix for transdermal drug delivery Download PDF

Info

Publication number
WO1996008229A3
WO1996008229A3 PCT/US1995/012163 US9512163W WO9608229A3 WO 1996008229 A3 WO1996008229 A3 WO 1996008229A3 US 9512163 W US9512163 W US 9512163W WO 9608229 A3 WO9608229 A3 WO 9608229A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
transdermal drug
matrix
softener
macromonomer
Prior art date
Application number
PCT/US1995/012163
Other languages
French (fr)
Other versions
WO1996008229A2 (en
Inventor
James E Garbe
Daniel C Duan
Cheryl L Moore
Jamieson C Keister
Original Assignee
Minnesota Mining & Mfg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23182561&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO1996008229(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Minnesota Mining & Mfg filed Critical Minnesota Mining & Mfg
Priority to NZ293849A priority Critical patent/NZ293849A/en
Priority to DE69517816T priority patent/DE69517816T2/en
Priority to JP51043296A priority patent/JP4102901B2/en
Priority to DK95933919T priority patent/DK0781122T3/en
Priority to AU36397/95A priority patent/AU702593B2/en
Priority to EP95933919A priority patent/EP0781122B1/en
Priority to AT95933919T priority patent/ATE194281T1/en
Publication of WO1996008229A2 publication Critical patent/WO1996008229A2/en
Publication of WO1996008229A3 publication Critical patent/WO1996008229A3/en
Priority to GR20000401412T priority patent/GR3033859T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/04—Polymers provided for in subclasses C08C or C08F
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J155/00—Adhesives based on homopolymers or copolymers, obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in groups C09J123/00 - C09J153/00
    • C09J155/005—Homopolymers or copolymers obtained by polymerisation of macromolecular compounds terminated by a carbon-to-carbon double bond

Abstract

A transdermal drug delivery device involving a macromonomer-containing acrylate or methacrylate copolymer, a softener, and a drug. Also a pressure sensitive skin adhesive involving a macromonomer containing acrylate or methacrylate copolymer and a softener.
PCT/US1995/012163 1994-09-14 1995-09-12 Matrix for transdermal drug delivery WO1996008229A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NZ293849A NZ293849A (en) 1994-09-14 1995-09-12 Transdermal delivery matrix comprising a macromonomer containing acrylate or metacrylate copolymer, a softener and a drug
DE69517816T DE69517816T2 (en) 1994-09-14 1995-09-12 MATRIX FOR TRANSDERMAL ACTIVE SUBSTANCE RELEASE
JP51043296A JP4102901B2 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug introduction
DK95933919T DK0781122T3 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug delivery
AU36397/95A AU702593B2 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug delivery
EP95933919A EP0781122B1 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug delivery
AT95933919T ATE194281T1 (en) 1994-09-14 1995-09-12 TRANSDERMAL ACTIVE RELEASE MATRIX
GR20000401412T GR3033859T3 (en) 1994-09-14 2000-07-06 Matrix for transdermal drug delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30583394A 1994-09-14 1994-09-14
US08/305,833 1994-09-14

Publications (2)

Publication Number Publication Date
WO1996008229A2 WO1996008229A2 (en) 1996-03-21
WO1996008229A3 true WO1996008229A3 (en) 1996-07-25

Family

ID=23182561

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/012163 WO1996008229A2 (en) 1994-09-14 1995-09-12 Matrix for transdermal drug delivery

Country Status (14)

Country Link
US (2) US7097853B1 (en)
EP (1) EP0781122B1 (en)
JP (1) JP4102901B2 (en)
KR (1) KR100382706B1 (en)
AT (1) ATE194281T1 (en)
AU (1) AU702593B2 (en)
CA (1) CA2198390C (en)
DE (1) DE69517816T2 (en)
DK (1) DK0781122T3 (en)
ES (1) ES2147858T3 (en)
GR (1) GR3033859T3 (en)
NZ (1) NZ293849A (en)
PT (1) PT781122E (en)
WO (1) WO1996008229A2 (en)

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US7097853B1 (en) 2006-08-29
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EP0781122B1 (en) 2000-07-05
AU3639795A (en) 1996-03-29
KR970705974A (en) 1997-11-03
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WO1996008229A2 (en) 1996-03-21
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US20060099242A1 (en) 2006-05-11
JP4102901B2 (en) 2008-06-18

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