WO1996025194A1 - Medication and apparatus and method of applying medication - Google Patents

Medication and apparatus and method of applying medication Download PDF

Info

Publication number
WO1996025194A1
WO1996025194A1 PCT/GB1996/000292 GB9600292W WO9625194A1 WO 1996025194 A1 WO1996025194 A1 WO 1996025194A1 GB 9600292 W GB9600292 W GB 9600292W WO 9625194 A1 WO9625194 A1 WO 9625194A1
Authority
WO
WIPO (PCT)
Prior art keywords
medication
mousse
foam
injuries
dispenser
Prior art date
Application number
PCT/GB1996/000292
Other languages
French (fr)
Inventor
William Nevil Heaton Johnson
Michael Paul Baylis
Original Assignee
Durand Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Durand Limited filed Critical Durand Limited
Publication of WO1996025194A1 publication Critical patent/WO1996025194A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams

Definitions

  • THIS INVENTION relates to medication for application to external injuries such as burns, scalds, cuts or abrasions or for application to legs affected by varicose veins, etc.
  • the invention also relates to apparatus for and a method of applying medication to external injuries.
  • apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
  • a medication for application to external injuries comprising any of the following alone or in combination:
  • the medication additionally comprises a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
  • a wool alcohol ointment and/or white soft paraphine petroleum jelly
  • a medication according to the second aspect of the invention is incorporated in a dispenser according to the first aspect of the invention for dispensing thereby in the form of a mousse or foam.
  • a dressing for external injuries including a moisture permeable pad impregnated with a medicament according to the second aspect of the invention.
  • a dispensing apparatus in the form of a pressurised container with a manually operable dispensing valve, known per se , the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually, the liquid is dispensed from the dispenser in the form of a foam or mousse.
  • the dispenser preferably has a suitable nozzle to facilitate application of the foam or mousse to a desired wound location.
  • the dispenser may be supplied with a plurality of interchangeable nozzles appropriate to different injuries or treatment situations.
  • one such nozzle may have a wide flat outlet for dispensing a wide ribbon of the foam or mousse
  • another nozzle may have an outlet in the form of a narrow bore for dispensing a fine strand of the foam or mousse
  • another nozzle may have an outlet in the form of a wider bore for dispensing a more substantial body of foam or mousse
  • a preferred medication comprises a mixture, with wool alcohols ointment and white soft paraphine, of a mixture of oils and other ingredients, referred to below, for convenience, as "Mixture A" and constituted as follows:-
  • Mixture A set out above is a concentrate and is not intended to be applied to the body in that concentrated form but only in dilution with a matrix material such as the wool alcohols ointment and white soft paraphine mixture referred to.
  • the medication described above is incorporated in a pressurised foam dispenser
  • the medication may also be supplied in jars in the conventional way.
  • the medication may be used to impregnate a moisture- permeable pad of a sticking plaster or other dressing, the sticking plaster or dressing, with the medication- impregnated pad being stored, in sterile condition, in a sealed package until required.
  • forms of medication other than that recited above may, in accordance with the invention, be dispensed in the form of a mousse or foam, including medications which are not strictly speaking liquid at the temperature, but for example in the form of a gel, such as petroleum jelly and medicaments having a petroleum jelly base.
  • the material dispensed in the form of a foam or mousse may be such that, after application, it will cure to form a flexible protective foam covering over the site of the injury, thereby serving as a substitute for a sticking plaster or dressing.
  • different medications may be supplied in similar dispensers embodying the invention, and the medications may be coloured to indicate the kind of medication used.
  • a setting medication may be of one colour; a medication specifically intended for burns may be of a different colour, and so on.
  • the container is pressurised by an appropriate propellant and foaming agent selected so as to be non-injurious to the patient and so as to be compatible with the medication.
  • the propellant or foaming agent may be, or include, a component having healing properties, for example, oxygen or carbon dioxide, for example, depending upon the treatment requirements.
  • the medication may also, if desired, incorporate a local anaesthetic.
  • the propellant may also act as the foaming agent.
  • the propellant and foaming agent may be distinct from one another.
  • the medication may incorporate a bleeding retarder or styptic.
  • a suitable medication in the form of a mousse to external injuries has various advantages. For example, it can be applied without contact of anything but the mousse with the injury and serves to cover the injury rapidly and thereby exclude germs etc.
  • Such a procedure has particular advantages, for example, in treating minor cuts and abrasions in small children or rashes such as "nappy rash", since the injury need not be touched and there is less chance of hurting the child.
  • the concealment of the injury by the mousse tends to minimise the child's alarm at the sight of the injury and provides reassurance.
  • a mousse also has advantages in more serious situations, as, for example, where injured persons are trapped so that an injury is not readily accessible for the application of normal wound dressings etc.
  • the dispenser may be fitted with a substantially elongate nozzle or nozzle extension which can readily be extended through relatively small openings to allow medication to be applied to injuries which can be seen but not readily reached by more conventional means, so that such medication can be applied, as a first-aid measure, even before trapped injured persons can be freed.

Abstract

Apparatus for applying medication to an external injury comprises a pressurised container of a liquid medicament under pressure of a propellant and incorporating a foaming agent. Upon depression of a manually operable valve fitted with a nozzle, the medicament is discharged from the nozzle in the form of a foam or mousse, directly onto the injury.

Description

Title: "Medication and apparatus and method of applying medication"
THIS INVENTION relates to medication for application to external injuries such as burns, scalds, cuts or abrasions or for application to legs affected by varicose veins, etc. The invention also relates to apparatus for and a method of applying medication to external injuries.
According to a first aspect of the invention there is provided apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
According to a second aspect of the invention there is provided a medication for application to external injuries, the medication comprising any of the following alone or in combination:
Eucalyptus oil
Menthol
Salicylic acid
Resorcinol
Chlorobutol
Methyl salicylate
Phenol
Oil citronella
Oil cloves
Industrial methylated spirit
Glacial acetic acid
Lignocaine alkaloid Preferably the medication additionally comprises a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
In a preferred embodiment of the invention, a medication according to the second aspect of the invention is incorporated in a dispenser according to the first aspect of the invention for dispensing thereby in the form of a mousse or foam.
According to a further aspect of the invention there is provided a dressing for external injuries including a moisture permeable pad impregnated with a medicament according to the second aspect of the invention.
In a preferred embodiment of the invention, a dispensing apparatus is provided in the form of a pressurised container with a manually operable dispensing valve, known per se , the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually, the liquid is dispensed from the dispenser in the form of a foam or mousse.
The dispenser preferably has a suitable nozzle to facilitate application of the foam or mousse to a desired wound location. Indeed, the dispenser may be supplied with a plurality of interchangeable nozzles appropriate to different injuries or treatment situations. For example, one such nozzle may have a wide flat outlet for dispensing a wide ribbon of the foam or mousse, another nozzle may have an outlet in the form of a narrow bore for dispensing a fine strand of the foam or mousse, another nozzle may have an outlet in the form of a wider bore for dispensing a more substantial body of foam or mousse, and so on. A preferred medication comprises a mixture, with wool alcohols ointment and white soft paraphine, of a mixture of oils and other ingredients, referred to below, for convenience, as "Mixture A" and constituted as follows:-
Mixture A
Eucalyptus oil 260 ml
Menthol 66 g
Salicylic acid 20 g
Resorcinol 56 g
Chlorobutol 240 g
Methyl salicylate (not Lin. Meth. Sal) 128 ml
Phenol crystals 160 g
Oil citronella 200 ml
Oil cloves 160 g
Industrial eths 472 ml
Glacial acetic acid 48 ml
Lignocaine alkaloid 400 g
The above quantities produce 2 litres of mixture A. Mixture A above was used in preparation of an ointment having the composition set out below:-
Mixture A 125 ml
Wool Alcohols Ointment 1 kg W.S.P. 4 kg
In preparation of the ointment, the 125 ml of Mixture A was mixed with about 300 grams of wool alcohol ointment (warmed if necessary) and shaken until the components "gelled" together. The remainder of the above- noted ingredients was added and the whole mixed thoroughly. It will be appreciated that Mixture A set out above is a concentrate and is not intended to be applied to the body in that concentrated form but only in dilution with a matrix material such as the wool alcohols ointment and white soft paraphine mixture referred to.
Whilst, in the preferred embodiment of the invention, the medication described above is incorporated in a pressurised foam dispenser, the medication may also be supplied in jars in the conventional way. Alternatively, the medication may be used to impregnate a moisture- permeable pad of a sticking plaster or other dressing, the sticking plaster or dressing, with the medication- impregnated pad being stored, in sterile condition, in a sealed package until required.
It will be appreciated that forms of medication other than that recited above may, in accordance with the invention, be dispensed in the form of a mousse or foam, including medications which are not strictly speaking liquid at the temperature, but for example in the form of a gel, such as petroleum jelly and medicaments having a petroleum jelly base.
It is also possible for the material dispensed in the form of a foam or mousse to be such that, after application, it will cure to form a flexible protective foam covering over the site of the injury, thereby serving as a substitute for a sticking plaster or dressing. If desired, different medications may be supplied in similar dispensers embodying the invention, and the medications may be coloured to indicate the kind of medication used. For example, a setting medication may be of one colour; a medication specifically intended for burns may be of a different colour, and so on. When the medication is supplied in a mousse- dispensing container, the container is pressurised by an appropriate propellant and foaming agent selected so as to be non-injurious to the patient and so as to be compatible with the medication. In appropriate cases, the propellant or foaming agent may be, or include, a component having healing properties, for example, oxygen or carbon dioxide, for example, depending upon the treatment requirements. The medication may also, if desired, incorporate a local anaesthetic. It will be appreciated that the propellant may also act as the foaming agent. However, the propellant and foaming agent may be distinct from one another.
The medication may incorporate a bleeding retarder or styptic.
Application of a suitable medication in the form of a mousse to external injuries has various advantages. For example, it can be applied without contact of anything but the mousse with the injury and serves to cover the injury rapidly and thereby exclude germs etc. Such a procedure has particular advantages, for example, in treating minor cuts and abrasions in small children or rashes such as "nappy rash", since the injury need not be touched and there is less chance of hurting the child. Furthermore the concealment of the injury by the mousse tends to minimise the child's alarm at the sight of the injury and provides reassurance.
Application in the form of a mousse also has advantages in more serious situations, as, for example, where injured persons are trapped so that an injury is not readily accessible for the application of normal wound dressings etc. For such situations the dispenser may be fitted with a substantially elongate nozzle or nozzle extension which can readily be extended through relatively small openings to allow medication to be applied to injuries which can be seen but not readily reached by more conventional means, so that such medication can be applied, as a first-aid measure, even before trapped injured persons can be freed.

Claims

1. Apparatus for applying medication to an external injury comprising a dispenser adapted to dispense medication, in the form of a mousse or foam, directly onto such injuries.
2. A medication for application to external injuries, the medication comprising any of the following alone or in combination:
Eucalyptus oil
Menthol
Salicylic acid
Resorcinol
Chlorobutol
Methyl salicylate
Phenol
Oil citronella
Oil cloves
Industrial methylated spirit
Glacial acetic acid
Lignocaine alkaloid
3. The medication of claim 2 additionally comprising a wool alcohol ointment and/or white soft paraphine (petroleum jelly) .
4. Apparatus according to claim 1 including a medication according to claim 2 or claim 3 within said dispenser for dispensing said medication in the form of a mousse of foam.
5. A dressing for external injuries including a moisture permeable pad impregnated with a medicament according to claim 2 or claim 3.
6. Apparatus according to claim 1 or claim 4 comprising a pressurised container with a manually operable dispensing valve, the container containing a quantity of a liquid medicament under pressure of a propellant and incorporating a foaming agent whereby when the valve is operated manually the liquid is dispensed from the dispenser in the form of a foam or mousse.
7. Apparatus according to claim 6 including a nozzle for application of the foam or mousse to a desired wound location.
8. Apparatus according to claim 7, including a plurality of interchangeable nozzles appropriate to different injuries or treatment situations.
PCT/GB1996/000292 1995-02-17 1996-02-12 Medication and apparatus and method of applying medication WO1996025194A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9503119.1A GB9503119D0 (en) 1995-02-17 1995-02-17 Medication and apparatus and method of applying medication
GB9503119.1 1995-02-17

Publications (1)

Publication Number Publication Date
WO1996025194A1 true WO1996025194A1 (en) 1996-08-22

Family

ID=10769765

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1996/000292 WO1996025194A1 (en) 1995-02-17 1996-02-12 Medication and apparatus and method of applying medication

Country Status (2)

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GB (1) GB9503119D0 (en)
WO (1) WO1996025194A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2353214A (en) * 1999-07-06 2001-02-21 Cooper John Philip Topical Composition
WO2002062420A1 (en) * 2001-01-22 2002-08-15 SØRENSEN, Svein Photodynamic stimulation device and methods
USRE38919E1 (en) 1993-06-23 2005-12-13 Btg International Limited Injectable microfoam containing a sclerosing agent
US7025290B2 (en) 1999-05-26 2006-04-11 Btg International Limited Generation of therapeutic microfoam
US7731986B2 (en) 2003-11-17 2010-06-08 Btg International Ltd. Therapeutic foam
US7842282B2 (en) 2000-11-24 2010-11-30 Btg International Limited Generation of therapeutic microfoam
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8263580B2 (en) 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
US8629128B2 (en) 2005-06-01 2014-01-14 Stiefel West Coast, Llc Vitamin formulation
US8703827B2 (en) 2005-05-13 2014-04-22 Btg International Ltd. Therapeutic foam

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0395329A2 (en) * 1989-04-26 1990-10-31 Smith Kline & French Laboratories Limited composition in the form of a foam containing 5-aminosalicylic acid for intra-rectal administration
EP0423695A2 (en) * 1989-10-19 1991-04-24 Sterling Drug Inc. Aerosol composition for topical medicament
US5059187A (en) * 1988-11-30 1991-10-22 Dey Laboratories, Inc. Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution
WO1992011839A1 (en) * 1991-01-08 1992-07-23 Leonard Mackles Anhydrous aerosol
US5143717A (en) * 1987-12-30 1992-09-01 Code Blue Medical Corporation Burn foam and delivery system
US5322683A (en) * 1989-05-01 1994-06-21 Leonard Mackles Anhydrous aerosol foam

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143717A (en) * 1987-12-30 1992-09-01 Code Blue Medical Corporation Burn foam and delivery system
US5059187A (en) * 1988-11-30 1991-10-22 Dey Laboratories, Inc. Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution
EP0395329A2 (en) * 1989-04-26 1990-10-31 Smith Kline & French Laboratories Limited composition in the form of a foam containing 5-aminosalicylic acid for intra-rectal administration
US5322683A (en) * 1989-05-01 1994-06-21 Leonard Mackles Anhydrous aerosol foam
EP0423695A2 (en) * 1989-10-19 1991-04-24 Sterling Drug Inc. Aerosol composition for topical medicament
WO1992011839A1 (en) * 1991-01-08 1992-07-23 Leonard Mackles Anhydrous aerosol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE40640E1 (en) 1993-06-23 2009-02-17 Btg International Ltd. Injectable microfoam containing a sclerosing agent
USRE38919E1 (en) 1993-06-23 2005-12-13 Btg International Limited Injectable microfoam containing a sclerosing agent
US8263580B2 (en) 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
US8091801B2 (en) 1999-05-26 2012-01-10 Btg International Limited Generation of therapeutic microfoam
US7025290B2 (en) 1999-05-26 2006-04-11 Btg International Limited Generation of therapeutic microfoam
US7604185B2 (en) 1999-05-26 2009-10-20 Btg International Ltd. Generation of therapeutic microfoam
US7357336B2 (en) 1999-05-26 2008-04-15 Btg International Limited Generation of therapeutic microfoam
GB2353214A (en) * 1999-07-06 2001-02-21 Cooper John Philip Topical Composition
US7842283B2 (en) 2000-11-24 2010-11-30 Btg International Limited Generation of therapeutic microfoam
US7842282B2 (en) 2000-11-24 2010-11-30 Btg International Limited Generation of therapeutic microfoam
WO2002062420A1 (en) * 2001-01-22 2002-08-15 SØRENSEN, Svein Photodynamic stimulation device and methods
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US7763269B2 (en) 2003-11-17 2010-07-27 Btg International Ltd. Therapeutic foam
US7731986B2 (en) 2003-11-17 2010-06-08 Btg International Ltd. Therapeutic foam
US8323677B2 (en) 2003-11-17 2012-12-04 Btg International Ltd. Therapeutic foam
US8703827B2 (en) 2005-05-13 2014-04-22 Btg International Ltd. Therapeutic foam
US8629128B2 (en) 2005-06-01 2014-01-14 Stiefel West Coast, Llc Vitamin formulation

Also Published As

Publication number Publication date
GB9503119D0 (en) 1995-04-05

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