WO1997012545A3 - Apparatus and method for measuring an induced perturbation to determine a physiological parameter - Google Patents

Apparatus and method for measuring an induced perturbation to determine a physiological parameter Download PDF

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Publication number
WO1997012545A3
WO1997012545A3 PCT/US1996/015820 US9615820W WO9712545A3 WO 1997012545 A3 WO1997012545 A3 WO 1997012545A3 US 9615820 W US9615820 W US 9615820W WO 9712545 A3 WO9712545 A3 WO 9712545A3
Authority
WO
WIPO (PCT)
Prior art keywords
physiological parameter
patient
noninvasive sensor
blood vessel
hemoparameter
Prior art date
Application number
PCT/US1996/015820
Other languages
French (fr)
Other versions
WO1997012545A2 (en
WO1997012545B1 (en
Inventor
Richard G Caro
Mark H Sher
Bryan P Flaherty
Original Assignee
Vital Insite Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/228,213 external-priority patent/US5590649A/en
Application filed by Vital Insite Inc filed Critical Vital Insite Inc
Priority to JP51439897A priority Critical patent/JP3703496B2/en
Priority to DE69618654T priority patent/DE69618654T2/en
Priority to AU72532/96A priority patent/AU7253296A/en
Priority to AT96934010T priority patent/ATE211371T1/en
Priority to EP96934010A priority patent/EP0855874B1/en
Publication of WO1997012545A2 publication Critical patent/WO1997012545A2/en
Publication of WO1997012545A3 publication Critical patent/WO1997012545A3/en
Publication of WO1997012545B1 publication Critical patent/WO1997012545B1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02133—Measuring pressure in heart or blood vessels by using induced vibration of the blood vessel

Abstract

A monitor for determining a patient's physiological parameter includes a calibration device configured to provide a calibration signal representative of the patient's physiological parameter. An exciter is positioned over a blood vessel of the patient for inducing a transmitted exciter waveform into the patient. A noninvasive sensor is positioned over the blood vessel, where the noninvasive sensor is configured to sense a hemoparameter and to generate a noninvasive sensor signal representative of the hemoparameter containing a component of a physiological parameter waveform and a component of a received exciter waveform. In this context, a hemoparameter is defined as any physiological parameter related to vessel blood such as pressure, flow, volume, velocity, blood vessel wall motion, blood vessel wall position and other related parameters. A processor is configured to determine a relationship between a property of the received exciter waveform and a property of the physiological parameter. The processor is connected to receive the calibration signal and the noninvasive sensor signal, and the processor is configured to process the calibration signal and the noninvasive sensor signal to determine the physiological parameter. In the preferred embodiment, the physiological parameter measured is blood pressure, however, the present invention can also be used to analyze and track other physiological parameters such as vascular wall compliance, strength of ventricular contractions, vascular resistance, fluid volume, cardiac output, myocardial contractility and other related parameters.
PCT/US1996/015820 1994-04-15 1996-10-02 Apparatus and method for measuring an induced perturbation to determine a physiological parameter WO1997012545A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP51439897A JP3703496B2 (en) 1994-04-15 1996-10-02 Apparatus and method for measuring induced perturbations and measuring physiological parameters
DE69618654T DE69618654T2 (en) 1994-04-15 1996-10-02 DEVICE AND METHOD FOR MEASURING AN INDUCED FAULT TO DETERMINE THE BLOOD PRESSURE
AU72532/96A AU7253296A (en) 1994-04-15 1996-10-02 Apparatus and method for measuring an induced perturbation to determine a physiological parameter
AT96934010T ATE211371T1 (en) 1994-04-15 1996-10-02 DEVICE AND METHOD FOR MEASURING AN INDUCED DISRUPTION TO DETERMINE BLOOD PRESSURE
EP96934010A EP0855874B1 (en) 1994-04-15 1996-10-02 Apparatus and method for measuring an induced perturbation to determine a physiological parameter

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/228,213 US5590649A (en) 1994-04-15 1994-04-15 Apparatus and method for measuring an induced perturbation to determine blood pressure
US551995P 1995-10-03 1995-10-03
US60/005,519 1995-11-22
US08/556,547 US5810734A (en) 1994-04-15 1995-11-22 Apparatus and method for measuring an induced perturbation to determine a physiological parameter
US08/556,547 1995-11-22

Publications (3)

Publication Number Publication Date
WO1997012545A2 WO1997012545A2 (en) 1997-04-10
WO1997012545A3 true WO1997012545A3 (en) 1997-05-09
WO1997012545B1 WO1997012545B1 (en) 1997-07-31

Family

ID=27357897

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/015820 WO1997012545A2 (en) 1994-04-15 1996-10-02 Apparatus and method for measuring an induced perturbation to determine a physiological parameter

Country Status (8)

Country Link
US (2) US5810734A (en)
EP (1) EP0855874B1 (en)
JP (1) JP3703496B2 (en)
AT (1) ATE211371T1 (en)
AU (1) AU7253296A (en)
CA (1) CA2233865A1 (en)
DE (1) DE69618654T2 (en)
WO (1) WO1997012545A2 (en)

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