WO1997013448A3 - Device for determining blood glucose level - Google Patents

Device for determining blood glucose level Download PDF

Info

Publication number
WO1997013448A3
WO1997013448A3 PCT/DE1996/001971 DE9601971W WO9713448A3 WO 1997013448 A3 WO1997013448 A3 WO 1997013448A3 DE 9601971 W DE9601971 W DE 9601971W WO 9713448 A3 WO9713448 A3 WO 9713448A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
eye
measurement radiation
retina
concentration
Prior art date
Application number
PCT/DE1996/001971
Other languages
German (de)
French (fr)
Other versions
WO1997013448A2 (en
Inventor
Gerhard Mueller
Original Assignee
Laser & Med Tech Gmbh
Gerhard Mueller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laser & Med Tech Gmbh, Gerhard Mueller filed Critical Laser & Med Tech Gmbh
Priority to DE29623431U priority Critical patent/DE29623431U1/en
Publication of WO1997013448A2 publication Critical patent/WO1997013448A2/en
Publication of WO1997013448A3 publication Critical patent/WO1997013448A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14558—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters by polarisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

The proposed device for determining blood glucose level comprises the following elements: a light source (3) for producing a measurement radiation used to illuminate a part (2) of the body using a wavelength for which the optical properties of the body part (2) depend on the concentration of the blood component in question; a light detector (10) for detecting the measurement radiation which has been attenuated in the body part (2) to a degree dependent on the said concentration; and an evaluation unit (12) for determining the concentration of the blood component as a function of the radiation detected. The illuminated body part is an eye (2) and the light detector (10) for measuring the reflected light is set up in the path of the radiation reflected or back scattered in the anterior chamber (1) of the eye. A focusing system (6) is mounted between the light source (3) and the illuminated eye (2) to prevent damage to the retina by the measurement radiation. The focusing system focuses the measurement radiation in the anterior chamber (1) of the eye in such a way that the radiation nearer to the retina is substantially blocked by the iris (7), and/or the selected wavelength of the measurement radiation lies within the absorption range of the aqueous humour in order to prevent damage to the retina.
PCT/DE1996/001971 1995-10-14 1996-10-14 Device for determining blood glucose level WO1997013448A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE29623431U DE29623431U1 (en) 1995-10-14 1996-10-14 Device for determining blood glucose

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19538372.9 1995-10-14
DE1995138372 DE19538372A1 (en) 1995-10-14 1995-10-14 Non-invasive glucose measurement

Publications (2)

Publication Number Publication Date
WO1997013448A2 WO1997013448A2 (en) 1997-04-17
WO1997013448A3 true WO1997013448A3 (en) 1997-05-29

Family

ID=7774914

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1996/001971 WO1997013448A2 (en) 1995-10-14 1996-10-14 Device for determining blood glucose level

Country Status (2)

Country Link
DE (2) DE19538372A1 (en)
WO (1) WO1997013448A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836979T2 (en) * 1997-11-12 2007-11-08 Lightouch Medical, Inc. METHOD FOR NON-INVASIVE ANALYTIC MEASUREMENT
ATE225142T1 (en) 1998-07-07 2002-10-15 Lightouch Medical Inc TISSUE MODULATION METHOD FOR QUANTITATIVE NON-INVASIVE IN VIVO SPECTROSCOPIC ANALYSIS OF TISSUE
US6494576B1 (en) 1999-09-30 2002-12-17 L'esperance, Jr. Francis A. Method and apparatus for spectrophotometry of the eye
DE10027100C2 (en) 2000-05-31 2002-08-08 Klaus Mueller-Dethlefs Method and device for detecting substances in body fluids
GB2407378B (en) 2003-10-24 2006-09-06 Lein Applied Diagnostics Ltd Ocular property measuring apparatus and method therefor
GB2409033C (en) 2003-12-12 2006-05-24 Lein Applied Diagnostics Ltd Extended focal region measuring apparatus and method
GB2451443B (en) 2007-07-30 2012-12-26 Lein Applied Diagnostics Ltd Optical measurement apparatus and method therefor
GB2457302B (en) 2008-02-11 2013-04-10 Lein Applied Diagnostics Ltd Measurement apparatus and method therefor
JP2017038681A (en) * 2015-08-18 2017-02-23 富士ゼロックス株式会社 Optical measurement device, and light irradiation and reception method
WO2018083112A1 (en) * 2016-11-01 2018-05-11 Universiteit Maastricht Device for performing measurements of the chemical composition of the anterior eye as well as an integrated optical unit for implementation therein

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963019A (en) * 1974-11-25 1976-06-15 Quandt Robert S Ocular testing method and apparatus
US4720191A (en) * 1985-11-19 1988-01-19 Carl-Zeiss-Stiftung Method and apparatus for light span microscopic dark-field display of objects
US4756305A (en) * 1986-09-23 1988-07-12 Mateik William J Eye training device
WO1992010131A1 (en) * 1990-12-14 1992-06-25 Georgia Tech Research Corporation Non-invasive blood glucose measurement system
WO1993001745A1 (en) * 1991-07-17 1993-02-04 Georgia Tech Research Corporation Measuring molecular change in the ocular lens
WO1993007801A1 (en) * 1991-10-17 1993-04-29 Scientific Generics Limited Method and apparatus for non-invasive blood analyte determination
EP0589191A1 (en) * 1992-09-04 1994-03-30 Edward W. Stark Non-invasive glucose measurement method and apparatus
EP0603658A1 (en) * 1992-12-19 1994-06-29 Boehringer Mannheim Gmbh Device for in-vivo determination of an optical property of the liquid of the aqueous humor of the eye

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963019A (en) * 1974-11-25 1976-06-15 Quandt Robert S Ocular testing method and apparatus
US4720191A (en) * 1985-11-19 1988-01-19 Carl-Zeiss-Stiftung Method and apparatus for light span microscopic dark-field display of objects
US4756305A (en) * 1986-09-23 1988-07-12 Mateik William J Eye training device
WO1992010131A1 (en) * 1990-12-14 1992-06-25 Georgia Tech Research Corporation Non-invasive blood glucose measurement system
WO1993001745A1 (en) * 1991-07-17 1993-02-04 Georgia Tech Research Corporation Measuring molecular change in the ocular lens
WO1993007801A1 (en) * 1991-10-17 1993-04-29 Scientific Generics Limited Method and apparatus for non-invasive blood analyte determination
EP0589191A1 (en) * 1992-09-04 1994-03-30 Edward W. Stark Non-invasive glucose measurement method and apparatus
EP0603658A1 (en) * 1992-12-19 1994-06-29 Boehringer Mannheim Gmbh Device for in-vivo determination of an optical property of the liquid of the aqueous humor of the eye

Also Published As

Publication number Publication date
DE19538372A1 (en) 1997-04-17
WO1997013448A2 (en) 1997-04-17
DE29623431U1 (en) 1998-07-02

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