WO1997032970A1 - Modified rapid expansion methods ('modified-rem') for in vitro propagation of t lymphocytes - Google Patents
Modified rapid expansion methods ('modified-rem') for in vitro propagation of t lymphocytes Download PDFInfo
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- WO1997032970A1 WO1997032970A1 PCT/US1997/003293 US9703293W WO9732970A1 WO 1997032970 A1 WO1997032970 A1 WO 1997032970A1 US 9703293 W US9703293 W US 9703293W WO 9732970 A1 WO9732970 A1 WO 9732970A1
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- cell
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- rapid expansion
- rem
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
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- Wood Science & Technology (AREA)
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- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
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DE69739951T DE69739951D1 (en) | 1996-03-04 | 1997-03-03 | MODIFIED QUICK-REINFORCEMENT METHOD ('MODIFIED-REM') FOR THE IN VITRO REPRODUCTION OF T-LYMPHOCYTES |
US08/793,707 US6316257B1 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods (“modified-REM”) for in vitro propagation of T lymphocytes |
AT97914841T ATE476496T1 (en) | 1996-03-04 | 1997-03-03 | MODIFIED RAPID DEVELOPMENT METHOD ('MODIFIED-REM') FOR THE IN VITRO PRODUCTION OF T-LYMPHOCYTES |
IL12588497A IL125884A0 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes |
JP53187797A JP2002516562A (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion method for in vitro expansion of T lymphocytes ("modified REM") |
AU21947/97A AU726198B2 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods ("modified-REM") for in vitro propagation of T lymphocytes |
EP97914841A EP0904350B1 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods ("modified-rem") for in vitro propagation of t lymphocytes |
US09/956,581 US6890753B2 (en) | 1996-03-04 | 2001-09-17 | Modified rapid expansion methods(“modified-REM”) for in vitro propagation of T lymphocytes |
US11/078,897 US20050164387A1 (en) | 1996-03-04 | 2005-03-10 | Modified rapid expansion methods ("modified-REM") for in vitro propagation of T lymphocytes |
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US61071096A | 1996-03-04 | 1996-03-04 | |
US08/610,710 | 1996-03-04 |
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US08/793,707 A-371-Of-International US6316257B1 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods (“modified-REM”) for in vitro propagation of T lymphocytes |
US09/956,581 Continuation US6890753B2 (en) | 1996-03-04 | 2001-09-17 | Modified rapid expansion methods(“modified-REM”) for in vitro propagation of T lymphocytes |
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Publication Number | Publication Date |
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WO1997032970A1 true WO1997032970A1 (en) | 1997-09-12 |
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PCT/US1997/003293 WO1997032970A1 (en) | 1996-03-04 | 1997-03-03 | Modified rapid expansion methods ('modified-rem') for in vitro propagation of t lymphocytes |
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AU (1) | AU726198B2 (en) |
CA (1) | CA2247131A1 (en) |
IL (1) | IL125884A0 (en) |
WO (1) | WO1997032970A1 (en) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0953351A2 (en) * | 1998-04-09 | 1999-11-03 | Teruaki Sekine | Medicaments containing, as the main ingredient, allogenic activated-CD4+ cells and method for producing the same |
WO2002014481A1 (en) * | 2000-08-16 | 2002-02-21 | Takara Bio Inc. | Method of extensive culture of antigen-specific cytotoxic t cells |
WO2003016511A1 (en) * | 2001-08-15 | 2003-02-27 | Takara Bio Inc. | Method of extended culture for antigen-specific cytotoxic t lumphocytes |
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Also Published As
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AU726198B2 (en) | 2000-11-02 |
IL125884A0 (en) | 1999-04-11 |
CA2247131A1 (en) | 1997-09-12 |
AU2194797A (en) | 1997-09-22 |
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