WO1997036681A1 - Device and method for multiple analyte detection - Google Patents
Device and method for multiple analyte detection Download PDFInfo
- Publication number
- WO1997036681A1 WO1997036681A1 PCT/US1997/005458 US9705458W WO9736681A1 WO 1997036681 A1 WO1997036681 A1 WO 1997036681A1 US 9705458 W US9705458 W US 9705458W WO 9736681 A1 WO9736681 A1 WO 9736681A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- die
- sample
- detection
- analyte
- chambers
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/06—Quantitative determination
- C12Q1/08—Quantitative determination using multifield media
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0642—Filling fluids into wells by specific techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00148—Test cards, e.g. Biomerieux or McDonnel multiwell test cards
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69700499T DE69700499T2 (en) | 1996-04-03 | 1997-04-02 | DEVICE AND METHOD FOR DETECTING SEVERAL ANALYZES |
EP97917816A EP0889751B1 (en) | 1996-04-03 | 1997-04-02 | Device and method for multiple analyte detection |
CA2250212A CA2250212C (en) | 1996-04-03 | 1997-04-02 | Device and method for multiple analyte detection |
JP53557597A JP4912517B2 (en) | 1996-04-03 | 1997-04-02 | Devices and methods for detection of multiple analytes |
AU26048/97A AU706862B2 (en) | 1996-04-03 | 1997-04-02 | Device and method for multiple analyte detection |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1471296P | 1996-04-03 | 1996-04-03 | |
US60/014,712 | 1996-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997036681A1 true WO1997036681A1 (en) | 1997-10-09 |
Family
ID=21767215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/005458 WO1997036681A1 (en) | 1996-04-03 | 1997-04-02 | Device and method for multiple analyte detection |
Country Status (7)
Country | Link |
---|---|
US (2) | US6126899A (en) |
EP (1) | EP0889751B1 (en) |
JP (3) | JP4912517B2 (en) |
AU (1) | AU706862B2 (en) |
CA (1) | CA2250212C (en) |
DE (1) | DE69700499T2 (en) |
WO (1) | WO1997036681A1 (en) |
Cited By (47)
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WO1999058244A1 (en) * | 1998-05-13 | 1999-11-18 | Bayer Corporation | Sample introduction device |
WO2000053318A1 (en) * | 1999-03-09 | 2000-09-14 | Biomerieux S.A. | Test sample card filled in combination with at least a buffer supply |
FR2790685A1 (en) * | 1999-03-09 | 2000-09-15 | Biomerieux Sa | Test card comprising a buffer volume to facilitate filling with a sample, useful for performing biological assays |
WO2001028684A2 (en) * | 1999-10-15 | 2001-04-26 | Pe Corporation (Ny) | System and method for filling a substrate with a liquid sample |
EP1110084A1 (en) * | 1998-08-03 | 2001-06-27 | Qualisys Diagnostics Inc. | Methods and apparatus for conducting tests |
US6329209B1 (en) | 1998-07-14 | 2001-12-11 | Zyomyx, Incorporated | Arrays of protein-capture agents and methods of use thereof |
WO2002006796A2 (en) | 2000-07-14 | 2002-01-24 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
EP1204859A2 (en) * | 1999-07-16 | 2002-05-15 | The Board Of Regents, The University Of Texas System | Method and apparatus for the delivery of samples to a chemical sensor array |
US6514750B2 (en) | 2001-07-03 | 2003-02-04 | Pe Corporation (Ny) | PCR sample handling device |
US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
US6638761B2 (en) | 2000-02-02 | 2003-10-28 | Applera Corporation | Thermal cycling device with mechanism for ejecting sample well trays |
EP1369699A1 (en) * | 1999-10-15 | 2003-12-10 | PE Corporation (NY) | System and method for filling a substrate with a liquid sample |
US6677151B2 (en) | 2002-01-30 | 2004-01-13 | Applera Corporation | Device and method for thermal cycling |
US6682942B1 (en) | 1998-07-14 | 2004-01-27 | Zyomyx, Inc. | Microdevices for screening biomolecules |
US6690467B1 (en) | 2000-05-05 | 2004-02-10 | Pe Corporation | Optical system and method for optically analyzing light from a sample |
EP1391241A1 (en) * | 1999-04-21 | 2004-02-25 | Clinical Micro Sensors | The use of microfluidic systems in the electrochemical detection of target analytes |
US6719949B1 (en) | 2000-06-29 | 2004-04-13 | Applera Corporation | Apparatus and method for transporting sample well trays |
US6744502B2 (en) | 2001-09-28 | 2004-06-01 | Pe Corporation (Ny) | Shaped illumination geometry and intensity using a diffractive optical element |
EP1524034A2 (en) * | 1996-06-28 | 2005-04-20 | Caliper Life Sciences, Inc. | Electropipettor and compensation means for electrophoretic bias |
US6897073B2 (en) | 1998-07-14 | 2005-05-24 | Zyomyx, Inc. | Non-specific binding resistant protein arrays and methods for making the same |
US6982166B2 (en) | 2002-05-16 | 2006-01-03 | Applera Corporation | Lens assembly for biological testing |
US7001496B2 (en) | 1996-06-28 | 2006-02-21 | Caliper Life Sciences, Inc. | Electropipettor and compensation means for electrophoretic bias |
US7157056B2 (en) | 1999-05-12 | 2007-01-02 | Bayer Corporation | Sample introduction device |
US7169353B1 (en) | 1999-03-09 | 2007-01-30 | Biomerieux S.A. | Apparatus enabling liquid transfer by capillary action therein |
USRE39566E1 (en) | 1999-09-29 | 2007-04-17 | Applera Corporation | Thermocycler and lifting element |
WO2007061305A2 (en) * | 2005-11-22 | 2007-05-31 | Stichting Top Institute Food And Nutrition | Sampling device for in vivo sampling of liquids from the gastrointestinal tract, process for the production thereof and mould or mask for use in the production process |
EP1252929A3 (en) * | 2000-12-29 | 2007-06-13 | The Provost Fellows and Scholars of the College of the Holy Undivided Trinity of Queen Elizabeth Near Dublin | Biochip assembly |
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US7419820B2 (en) | 2003-12-16 | 2008-09-02 | Canon Kabushiki Kaisha | Transfer sheet for transferring biologically active substance to culture plate |
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US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
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Also Published As
Publication number | Publication date |
---|---|
CA2250212A1 (en) | 1997-10-09 |
CA2250212C (en) | 2010-02-09 |
EP0889751A1 (en) | 1999-01-13 |
US6124138A (en) | 2000-09-26 |
JP4912517B2 (en) | 2012-04-11 |
JP2011177179A (en) | 2011-09-15 |
EP0889751B1 (en) | 1999-09-08 |
DE69700499T2 (en) | 2000-03-23 |
AU2604897A (en) | 1997-10-22 |
JP2009025313A (en) | 2009-02-05 |
DE69700499D1 (en) | 1999-10-14 |
JP2000508528A (en) | 2000-07-11 |
AU706862B2 (en) | 1999-06-24 |
US6126899A (en) | 2000-10-03 |
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