WO1997040129A1 - N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators - Google Patents
N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators Download PDFInfo
- Publication number
- WO1997040129A1 WO1997040129A1 PCT/US1997/004048 US9704048W WO9740129A1 WO 1997040129 A1 WO1997040129 A1 WO 1997040129A1 US 9704048 W US9704048 W US 9704048W WO 9740129 A1 WO9740129 A1 WO 9740129A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- acyl
- enzyme
- ed3a
- detergent composition
- surfactants
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/04—Carboxylic acids or salts thereof
- C11D1/10—Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
Definitions
- Ethylenediaminetriacetic acid (ED3A) and its salts have applications in the field of chelating chemistry, and may be used as a starting material in the preparation of strong chelating polymers, oil soluble chelants, surfactants and others.
- Conventional routes for the synthesis of ethylenediaminetriacetic acid were achieved via its N-benzyl derivative, which was subsequently hydrolyzed in alkaline solutions to ED3ANa 3 , thus avoiding cyclization to its 2-oxo-l ,4-piperazinediacetic acid (3KP) derivative.
- a cyanide source such as gaseous or liquid hydrogen cyanide, aqueous solutions of hydrogen cyanide or alkali metal cyanide, in stoichiometric amounts or in a slight molar excess, across this cyclic material at temperatures between 0° and 110°C, preferably between 0° and 65 °C, forms ethylenediamine N,N'-diacetic acid-N'-cyanomethyl or salts thereof (mononitrile-diacid).
- a cyanide source such as gaseous or liquid hydrogen cyanide, aqueous solutions of hydrogen cyanide or alkali metal cyanide, in stoichiometric amounts or in a slight molar excess, across this cyclic material at temperatures between 0° and 110°C, preferably between 0° and 65 °C, forms ethylenediamine N,N'-diacetic acid-N'-cyanomethyl or salts thereof (mononitrile-diacid).
- the nitrile in aqueous solutions may be spontaneously cyclized in the presence of less than 3.0 moles base: mole ED2AH 2 , the base including alkali metal or alkaline earth metal hydroxides, to form 2-oxo-l,4-piperazinediacetic acid (3KP) or salts thereof, which is the desired cyclic intermediate.
- 3KP 2-oxo-l,4-piperazinediacetic acid
- salts of ED3A are formed in excellent yield and purity.
- This patent also discloses an alternative embodiment in which the starting material is ED2AH a X b , where X is a base cation, e.g., an alkali or alkaline earth metal, a is 1 to 2, and b is 0 to 1 in aqueous solutions.
- the reaction mixture also can be acidified to ensure complete formation of carboxymethyl-2-oxopiperazine (the lactam) prior to the reaction.
- Formaldehyde is added, essentially resulting in the hydroxymethyl derivative.
- a cyanide source l-cyanomethyl-4- carboxymethyl-3-ketopiperazine (mononitrile monoacid) or a salt thereof is formed.
- HOCH 2 CN which is the reaction product of formaldehyde and cyanide, may also be employed in this method.
- this material may be hydrolyzed to 3KP. The addition of a base will open this ring structure to form the salt of ED3A.
- N-acyl ED3A derivatives discloses N-acyl ED3A derivatives and a process for producing the same.
- the production of N-acyl derivatives of ethylenediaminetriacetic acid can be accomplished according to the following general reaction scheme:
- the starting ED3A derivative can be the acid itself, or suitable salts thereof, such as alkali metal and alkaline earth metal salts, preferably sodium or potassium salts.
- n 4 to 40
- N-acyl ethylenediaminetriacetic acid derivatives such as dicarboxylic acid derivatives having the following general formula also can be produced:
- Specific examples include mono and di ED3A derivatives such as oxalyldi ED3A, oxalylmono ED3A, maleylmono ED3A, maleyldi ED3A, succinoylmono ED3A, succinoyldi ED3A, etc.
- ethylenediaminetriacetic acid (ED3A) and its salts now can be readily produced in bulk and high yield.
- Enzymes such as proteases, lipases and amylases, are commonly used to enhance the performance of fabric detergents, dish washing liquids, hard surface cleaners, drain opening fluids, etc.
- an enzyme in a detergent, it is possible to hydrolyze the proteins or starch residues on fabrics to such a degree that they become readily soluble in water.
- a more effective removal of difficult protein or starch stains including blood, mucus, and sweat, food products, etc. can be achieved.
- insoluble proteins and starches cause dirt to adhere strongly to fabrics, increasing the protein and starch solubility helps remove dirt as well.
- Commercial enzymes are produced mainly by living cells such as yeasts, and are proteinaceous in nature. Enzymes with enhanced activity for commercial use are often produced by genetic engineering.
- enzyme used depends on the detergent formulation and application conditions, especially since any given enzyme typically exhibits a maximum effectiveness at specific pH's and temperatures. Above their peak effectiveness temperature, they usually become denatured and never regain their activity. Enzymes are often denatured or deactivated by harsh surfactants such as sodium lauryl sulfate or linear alkyl benzene sulfate that are also common to detergent formulations. It is believed that this denaturing or deactivation is due to the disturbance of the three dimensional structure of the protein. Metal ions such as copper +2 , iron, nickel +2 , cobalt, etc. can also deactivate enzymes, possibly by interacting with and blocking the active site of the enzyme. It is therefore an object of the present invention to provide enzyme compatible surfactants. It is a further object of the present invention to provide detergent compositions containing an enzyme and an enzyme compatible surfactant.
- compositions including one or more enzymes and one or more surfactants provided that at least one of the surfactants is an N-acyl ethylenediaminetriacetic acid or salt thereof.
- the present inventors have found that N-acyl ED3A is highly compatible with various enzymes, and enhances their detergent effectiveness to an unexpected degree. Thue use of such surfactants with other enzyme systems, such as industrial processes, is also contemplated.
- Suitable acyl groups in the N-acyl ED3A surfactant include straight or branched aliphatic or aromatic groups containing from 1 to 40 carbon atoms, such as pentanoyl, hexanoyl, heptanoyl, octanoyl, nananoyl, decanoyl, lauroyl, myristoyl, palmitoyl, oleoyl, stearoyl and nonanoyl.
- Suitable branched acyl groups include neopentanoyl, neoheptanoyl, neodecanoyl, iso-octanoyl, iso-nananoyl and iso-tridecanoyl.
- Suitable aromatic acyl groups include benzoyl and napthoyl.
- the fatty acid chains may be substituted, such as by one or more halogen and/or hydroxyl groups.
- hydroxy-substituted fatty acids including ipurolic (3,11-dihyroxytetradecanoic), ustilic (2,15, 16-trihydroxyhexadecanoic), ambrettolic (16-hydroxy-7-hexadecanoic), ricinoleic
- Suitable halogen- substituted fatty acids include trifluoromethylbenzoyl chloride, pentadecafluoro-octanoyl chloride, pentafluoropropionoyl chloride, pentafluorobenzoyl chloride, perfluorostearoyl chloride, perfluorononamoyl chloride, perfluoroheptanoyl chloride and trifluoromethylacetyl chloride.
- the N-acyl group contains from 8 to 18 carbon atoms.
- N-acyl ED3A molecules allow for dispersion of fatty soils and thus enhance the activity of lipases against fatty soils.
- interfacial tension between the aqueous phase and the oily phase is reduced, interfacial area is increased, allowing the enzyme in the aqueous phase more surface to attack, thereby increasing the rate of reaction.
- Enhanced wetting of soils allows for more efficient attack by the enzymes, such as proteases, on deposited proteinaceous soils.
- the stability of N-acyl ED3A is not inhibited by the presence of excess electrolyte, such as sodium chloride, and multivalent hardness ions, such as Ca + + and Mg + + .
- the N-acyl ED3A is preferably used in the form of its salts, in view of their solubility. Where the N-acyl ED3A acid is first produced, it can be readily converted into salts by partial or complete neutralization of the acid with the appropriate base. The acid also can be produced from N-acyl ED3A salts by neutralization of the base with a quantitative amount of acid.
- the preferred chelating surfactants for use in the detergent compositions of the present invention are sodium and potassium lauroyI-ED3A.
- Suitable counterions include triethanolamine, diethanolamine, monoethanolamine, ammonium, isopropyl amine, N-propylamine and amino alcohols such as 2-amino-l- butanol, 2-amino-2-methyl-l,3-propane diol, 2-amino-2-me ⁇ hyl-l-propanol, 2-amino-2- ethyl- 1,3-propane diol and ⁇ ' 5(hydroxylmethyl) aminomethane.
- the N-acyl ED3A salt can be used in the detergent compositions of the present invention alone or in combination with other surfactants.
- the total amount of surfactant in the composition is between about 5 to about 30%, more preferably from about 10 to about 25%, most preferably about 12%.
- the pH of the detergent composition depends in part on the particular enzyme being used, but generally is within a range of about 7 to about 12. Suitable enzymes include proteolytic enzymes such as Alcalase * , Esperase", Savinase * , and DurazymTM, amylases such as Termamyl * , BAN, lipases such as Lipolase * , and cellulases.
- Savinase * is a serine protease having an optimum pH of 9- 11 and an optimum temperature of 55 °C.
- Avinase * for example, has an optimum pH of about 6-8 and an optimum temperature of about 60 °C.
- Lipases have the ability to decompose hydrophobic substances (such as hydrophobic triglycerides) into more hydrophilic compounds which are more easily removed by detergent action.
- detergent formulations typically comprise about 13- 25% builder, such as nitrilotriacetic acid, phosphates and zeolites. Up to about 25% bleach persalts also can be added.
- Conventional surfactants that may be used in combination with the N-acyl ED3A include anionics such as sarcosinates (including oleoyl, lauroyl and myristoyl), soluble linear alkylbenzene sulfonate, alkyl sulfate and alkyl ethoxy sulfates, sodium lauryl ether sulfate; nonionics such as alcohol ethyoxylates and alkyl polyglycosides; cationics such as C 12 -C 14 trimethyl ammonium chloride, di- tallow di-methyl ammonium chloride; and di-tallow methylamine, etc. , and many of the foregoing are often used in combination, such as a binary mixture of linear alkyl
- ingredients conventionally added to detergent compositions may be included, such as soap, dyes, perfumes, thickeners, conditioners, emollients, buffering agents, opacifiers, preservatives, optical brighteners, fabric softeners, etc.
- Enzymes Durazym 6.0 T or 0.6-1.5%
- EXAMPLE 1 Myristoyl and lauroyl ED3A acids were neutralized with aqueous sodium hydroxide to produce a 20% wt. Al solution. The resulting sodium lauroyl ED3A and sodium myristoyl ED3A were used at a concentration of 0.2% wt. Ten grams of surfactant (20%wt. Al) were added to 990 grams of distilled deionized water to produce the 0.2% wt. solution. One milliliter of protease enzyme (Savinase ' 16.0 L type EX available commercially from Novo Nordisk) was diluted to 100 ml. with distilled deionized water. 1.43 ml of the enzyme solution was then added to four of five Tergotometer cells and allowed to acclimate for 20 minutes. The cell contents were as follows: Table 1 : Cell Contents
- Cotton test swatches soiled with blood/ink/milk were placed in each cell and allowed to soak for 90 minutes. The tergotometer was activated and the swatches were washed for thirty minutes. After thirty minutes, the wash water was decanted. One liter of distilled, deionized water was then added to each cell and the cells were placed back into the tergotometer, which was then activated for 10 minutes. The water was then decanted and the test fabric was removed and placed on a piece of white cardboard. The fabric was allowed to air dry overnight.
- Myristoyl and oleoyl ED3A acids were neutralized with aqueous sodium hydroxide to produce a 20% wt. Al solution.
- a linear alkyl benzene sulfonate namely, a 40%wt Al sodium dodecylbenzene sulfonate solution (Strepantan DS-40) was diluted with distilled deionized water to produce a 20%wt Al solution.
- zeolite A 30.2 wt% sodium carbonate 20.8 wt% sodium sulfate 30.2 wt% sodium silicate 5.2 wt% cmc 1.0 wt%
- the overall detergent concentration tested was 3.5 grams of detergent/liter of water. Thus, the amount of dry detergent charged into each cell was 3.06 grams, whereas the amount of liquid surfactant charged to each cell was 2.18 grams (using 20%wt Al surfactant).
- the exact weights used are shown in Table 5 below:
- the surfactant portion of the detergent was added to each cell (containing one liter of distilled deionized water). The pH was adjusted to 8.3 with dilute NaOH. The remaining portion of the detergent was then added to the solution. The temperature of the solution in each cell was 48 °C and the pH was 10.5.
- protease enzyme Savinase* 16.0 L type EX available commercially from Novo Nordisk
- distilled deionized water 1.43 ml of the enzyme solution was then added to three of six Tergotometer cells and allowed to acclimate for 10 minutes.
- Cotton test swatches soiled with blood/ink/milk were placed in each cell and the tergotometer was activated and the swatches were washed for thirty minutes. After thirty minutes, the wash water was decanted. One liter of distilled, deionized water was then added to each cell and the cells were placed back into the tergotometer, which was then activated for 10 minutes. The water was then decanted and the test fabric was removed and placed on a piece of white cardboard. The fabric was allowed to air dry overnight.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU22116/97A AU710487B2 (en) | 1996-04-25 | 1997-03-12 | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
EP97915080A EP0914411A4 (en) | 1996-04-25 | 1997-03-12 | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
BR9708781A BR9708781A (en) | 1996-04-25 | 1997-03-12 | Surfactants of n-acyl ethylenediamino triacetic acids as stabilizing surfactants and activators compatible with enzymes |
DE0914411T DE914411T1 (en) | 1996-04-25 | 1997-03-12 | N-ACYL ETHYLENAMINE ACIDIC ACID COMPATIBLE SURFACES, STABILIZERS AND ACTIVATORS |
JP9538050A JP2000509087A (en) | 1996-04-25 | 1997-03-12 | N-acylethylenediaminetriacetic acid surfactants as enzyme-compatible surfactants, stabilizers and activators |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/637,575 US5821215A (en) | 1996-04-25 | 1996-04-25 | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
US08/637,575 | 1996-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997040129A1 true WO1997040129A1 (en) | 1997-10-30 |
Family
ID=24556533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/004048 WO1997040129A1 (en) | 1996-04-25 | 1997-03-12 | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
Country Status (10)
Country | Link |
---|---|
US (2) | US5821215A (en) |
EP (1) | EP0914411A4 (en) |
JP (1) | JP2000509087A (en) |
CN (1) | CN1216576A (en) |
AU (1) | AU710487B2 (en) |
BR (1) | BR9708781A (en) |
CA (1) | CA2249591A1 (en) |
DE (1) | DE914411T1 (en) |
ES (1) | ES2134178T1 (en) |
WO (1) | WO1997040129A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0906393A1 (en) * | 1996-04-25 | 1999-04-07 | Hampshire Chemical Corporation | Ultra mild detergent compositions |
EP0976392A1 (en) * | 1998-07-29 | 2000-02-02 | Unilever Plc | Liquid compositions comprising antioxidants and ED3A-derived chelating surfactants as stabilizers |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5821215A (en) * | 1996-04-25 | 1998-10-13 | Hampshire Chemical Corp. | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
JP2001522390A (en) * | 1997-04-24 | 2001-11-13 | チャーチ アンド ドワイト カンパニー インコーポレーテッド | Toilet flush hygiene compositions and systems, and methods of using the same |
US6280757B1 (en) * | 1997-05-22 | 2001-08-28 | The Procter & Gamble Company | Cleansing articles for skin or hair |
US6323118B1 (en) * | 1998-07-13 | 2001-11-27 | Taiwan Semiconductor For Manufacturing Company | Borderless dual damascene contact |
US6509284B1 (en) | 1999-02-26 | 2003-01-21 | Kimberly-Clark Worldwide, Inc. | Layer materials treated with surfacant-modified chelating agents |
US6433243B1 (en) | 1999-02-26 | 2002-08-13 | Kimberly-Clark Worldwide, Inc. | Water permeable porous layer materials treated with surfactant-modified cyclodextrins |
US6479150B1 (en) | 1999-02-26 | 2002-11-12 | Kimberly-Clark Worldwide, Inc. | Layer materials treated with surfactant-modified hydrophobic odor control agents |
EP1307547B1 (en) * | 2000-07-28 | 2005-10-26 | Henkel Kommanditgesellschaft auf Aktien | Novel amylolytic enzyme extracted from bacillus sp. a 7-7 (dsm 12368) and washing and cleaning agents containing this novel amylolytic enzyme |
WO2002066590A1 (en) * | 2000-12-12 | 2002-08-29 | Colgate-Palmolive Company | Grease cutting light duty liquid detergent |
US20030220211A1 (en) * | 2000-12-15 | 2003-11-27 | The Procter & Gamble Company | Methods, compositions, and articles for control of malodor produced by urea-containing body fluids |
US6852904B2 (en) | 2001-12-18 | 2005-02-08 | Kimberly-Clark Worldwide, Inc. | Cellulose fibers treated with acidic odor control agents |
US6767553B2 (en) | 2001-12-18 | 2004-07-27 | Kimberly-Clark Worldwide, Inc. | Natural fibers treated with acidic odor control/binder systems |
US20030228352A1 (en) * | 2002-06-07 | 2003-12-11 | The Procter & Gamble Company | Cleansing articles for skin or hair |
US7115551B2 (en) * | 2002-06-07 | 2006-10-03 | The Procter & Gamble Company | Cleansing articles for skin or hair |
EP1792972A1 (en) * | 2002-12-23 | 2007-06-06 | Alcon, Inc. | Use of multifuctional surface active agents to clean contact lenses |
TWI322828B (en) * | 2002-12-23 | 2010-04-01 | Alcon Inc | Use of multifunctional surface active agents to clean contact lenses |
US7172703B2 (en) * | 2003-07-18 | 2007-02-06 | Bj Services Co | Method of reclaiming a well completion brine solutions using an organic chelant |
US7144512B2 (en) * | 2003-07-18 | 2006-12-05 | Bj Services Company | Method of reclaiming brine solutions using an organic chelant |
US7678281B2 (en) * | 2003-07-18 | 2010-03-16 | Bj Services Company | Method of reclaiming brine solutions using an organic chelant |
US7674384B2 (en) * | 2003-07-18 | 2010-03-09 | Bj Services Company | Method of reclaiming brine solutions using an organic chelant |
US20100305015A1 (en) * | 2006-10-20 | 2010-12-02 | Innovation Deli Limited | Skin cleansing compositions |
EP2083067A1 (en) | 2008-01-25 | 2009-07-29 | Basf Aktiengesellschaft | Use of organic complexing agents and/or polymeric compounds containing carbonic acid groups in a liquid washing or cleaning agent compound |
US8258334B2 (en) * | 2008-11-12 | 2012-09-04 | Irix Pharmaceuticals, Inc. | N-alkanoyl-N,N′,N′-alkylenediamine trialkanoic acid esters |
GB2538498B (en) * | 2015-05-15 | 2017-12-20 | Henkel IP & Holding GmbH | Anaerobically curable (meth) acrylate compositions characterised by stabilisers with at least one glycinate group |
US10183087B2 (en) * | 2015-11-10 | 2019-01-22 | American Sterilizer Company | Cleaning and disinfecting composition |
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US4595527A (en) * | 1984-09-25 | 1986-06-17 | S. C. Johnson & Son, Inc. | Aqueous laundry prespotting composition |
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US5284972A (en) * | 1993-06-14 | 1994-02-08 | Hampshire Chemical Corp. | N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same |
US5466394A (en) * | 1994-04-25 | 1995-11-14 | The Procter & Gamble Co. | Stable, aqueous laundry detergent composition having improved softening properties |
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US5250728A (en) * | 1991-12-12 | 1993-10-05 | Hampshire Chemical Corp. | Preparation of ethylenediaminetriacetic acid |
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US5821215A (en) * | 1996-04-25 | 1998-10-13 | Hampshire Chemical Corp. | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
US5688981A (en) * | 1996-11-21 | 1997-11-18 | Hampshire Chemical Corp. | Ethylenediaminetriacetic acid and N-acyl ethylenediaminetriacetic acid silver chelating agents and surfactants |
-
1996
- 1996-04-25 US US08/637,575 patent/US5821215A/en not_active Expired - Fee Related
-
1997
- 1997-03-12 BR BR9708781A patent/BR9708781A/en unknown
- 1997-03-12 WO PCT/US1997/004048 patent/WO1997040129A1/en not_active Application Discontinuation
- 1997-03-12 DE DE0914411T patent/DE914411T1/en active Pending
- 1997-03-12 CA CA002249591A patent/CA2249591A1/en not_active Abandoned
- 1997-03-12 CN CN97194073.8A patent/CN1216576A/en active Pending
- 1997-03-12 ES ES97915080T patent/ES2134178T1/en active Pending
- 1997-03-12 EP EP97915080A patent/EP0914411A4/en not_active Withdrawn
- 1997-03-12 JP JP9538050A patent/JP2000509087A/en active Pending
- 1997-03-12 AU AU22116/97A patent/AU710487B2/en not_active Ceased
-
1998
- 1998-10-07 US US09/167,793 patent/US6057277A/en not_active Expired - Fee Related
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US4680131A (en) * | 1983-04-20 | 1987-07-14 | The Proctor & Gamble Company | Detergent compositions |
US4595527A (en) * | 1984-09-25 | 1986-06-17 | S. C. Johnson & Son, Inc. | Aqueous laundry prespotting composition |
US5284972A (en) * | 1993-06-14 | 1994-02-08 | Hampshire Chemical Corp. | N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same |
US5466394A (en) * | 1994-04-25 | 1995-11-14 | The Procter & Gamble Co. | Stable, aqueous laundry detergent composition having improved softening properties |
Non-Patent Citations (1)
Title |
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See also references of EP0914411A4 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0906393A1 (en) * | 1996-04-25 | 1999-04-07 | Hampshire Chemical Corporation | Ultra mild detergent compositions |
EP0906393A4 (en) * | 1996-04-25 | 2000-10-25 | Hampshire Chemical Corp | Ultra mild detergent compositions |
EP0976392A1 (en) * | 1998-07-29 | 2000-02-02 | Unilever Plc | Liquid compositions comprising antioxidants and ED3A-derived chelating surfactants as stabilizers |
Also Published As
Publication number | Publication date |
---|---|
AU710487B2 (en) | 1999-09-23 |
ES2134178T1 (en) | 1999-10-01 |
EP0914411A1 (en) | 1999-05-12 |
BR9708781A (en) | 1999-08-03 |
AU2211697A (en) | 1997-11-12 |
CA2249591A1 (en) | 1997-10-30 |
EP0914411A4 (en) | 2000-06-07 |
US5821215A (en) | 1998-10-13 |
JP2000509087A (en) | 2000-07-18 |
CN1216576A (en) | 1999-05-12 |
DE914411T1 (en) | 2000-06-08 |
US6057277A (en) | 2000-05-02 |
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