WO1998019626A3 - Method and device for continuous intralumenal delivery of bioactive substances - Google Patents

Method and device for continuous intralumenal delivery of bioactive substances Download PDF

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Publication number
WO1998019626A3
WO1998019626A3 PCT/US1997/020686 US9720686W WO9819626A3 WO 1998019626 A3 WO1998019626 A3 WO 1998019626A3 US 9720686 W US9720686 W US 9720686W WO 9819626 A3 WO9819626 A3 WO 9819626A3
Authority
WO
WIPO (PCT)
Prior art keywords
disk
tether
penetration
continuous
body lumen
Prior art date
Application number
PCT/US1997/020686
Other languages
French (fr)
Other versions
WO1998019626A2 (en
Inventor
Aaron V Kaplan
Original Assignee
Localmed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Localmed Inc filed Critical Localmed Inc
Priority to AU70003/98A priority Critical patent/AU7000398A/en
Publication of WO1998019626A2 publication Critical patent/WO1998019626A2/en
Publication of WO1998019626A3 publication Critical patent/WO1998019626A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Abstract

A method for the controlled release of a bioactive agent to a body lumen comprises forming percutaneous penetration to the lumen. An eluting element (10) comprising a bioerodible disk (12) is introduced through the tissue penetration with a tether (14) attached to the disk (12) passing outwardly through the penetration. The disk (12) may be secured within the body lumen by taping or otherwise attaching the tether to the patient's skin. The bioactive agent is released into the body lumen, which may be a blood vessel, as the disk erodes over time. Preferably, the tether (14) is also bioerodible and is resorbed as the tissue penetration heals.
PCT/US1997/020686 1996-11-05 1997-11-04 Method and device for continuous intralumenal delivery of bioactive substances WO1998019626A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU70003/98A AU7000398A (en) 1996-11-05 1997-11-04 Method and device for continuous intralumenal delivery of bioactive substances

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74176296A 1996-11-05 1996-11-05
US08/741,762 1996-11-05

Publications (2)

Publication Number Publication Date
WO1998019626A2 WO1998019626A2 (en) 1998-05-14
WO1998019626A3 true WO1998019626A3 (en) 1998-09-17

Family

ID=24982077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/020686 WO1998019626A2 (en) 1996-11-05 1997-11-04 Method and device for continuous intralumenal delivery of bioactive substances

Country Status (2)

Country Link
AU (1) AU7000398A (en)
WO (1) WO1998019626A2 (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699788A (en) * 1984-08-20 1987-10-13 Trustees Of Boston University Angiogenic factor methods of extraction and method for producing angiogenesis
US4744364A (en) * 1987-02-17 1988-05-17 Intravascular Surgical Instruments, Inc. Device for sealing percutaneous puncture in a vessel
US4790819A (en) * 1987-08-24 1988-12-13 American Cyanamid Company Fibrin clot delivery device and method
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US5108421A (en) * 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5292332A (en) * 1992-07-27 1994-03-08 Lee Benjamin I Methods and device for percutanceous sealing of arterial puncture sites
US5391183A (en) * 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US5443481A (en) * 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699788A (en) * 1984-08-20 1987-10-13 Trustees Of Boston University Angiogenic factor methods of extraction and method for producing angiogenesis
US4744364A (en) * 1987-02-17 1988-05-17 Intravascular Surgical Instruments, Inc. Device for sealing percutaneous puncture in a vessel
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4790819A (en) * 1987-08-24 1988-12-13 American Cyanamid Company Fibrin clot delivery device and method
US5391183A (en) * 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US5108421A (en) * 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5292332A (en) * 1992-07-27 1994-03-08 Lee Benjamin I Methods and device for percutanceous sealing of arterial puncture sites
US5443481A (en) * 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites

Also Published As

Publication number Publication date
AU7000398A (en) 1998-05-29
WO1998019626A2 (en) 1998-05-14

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